LOCUS       NZ_CP048397            21083 bp    DNA     linear   CON 08-MAY-2024
DEFINITION  Streptomyces sp. S4.7 chromosome, complete genome.
ACCESSION   NZ_CP048397
VERSION     NZ_CP048397.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. S4.7
  ORGANISM  Streptomyces sp. S4.7
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7920066)
  AUTHORS   Bekiesch,P., Zehl,M., Domingo-Contreras,E., Martin,J.,
            Perez-Victoria,I., Reyes,F., Kaplan,A., Ruckert,C., Busche,T.,
            Kalinowski,J. and Zotchev,S.
  TITLE     Viennamycins: new lipopeptides produced by Streptomyces sp. S4.7
            isolated from the rhizosphere of Edelweiss (Leontopodium nivale
            subsp. alpinum)
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7920066)
  AUTHORS   Bekiesch,P., Zehl,M., Domingo-Contreras,E., Martin,J.,
            Perez-Victoria,I., Reyes,F., Kaplan,A., Ruckert,C., Busche,T.,
            Kalinowski,J. and Zotchev,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-FEB-2020) CeBiTec, Uni Bielefeld, Sequenz 1, Bielefeld
            33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8; canu v. 1.6
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 57.8x
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_010384365.1-RS_2024_05_06
            Annotation Date                   :: 05/06/2024 10:27:30
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,027
            CDSs (total)                      :: 6,939
            Genes (coding)                    :: 6,650
            CDSs (with protein)               :: 6,650
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 289
            CDSs (without protein)            :: 289
            Pseudo Genes (ambiguous residues) :: 0 of 289
            Pseudo Genes (frameshifted)       :: 103 of 289
            Pseudo Genes (incomplete)         :: 223 of 289
            Pseudo Genes (internal stop)      :: 23 of 289
            Pseudo Genes (multiple problems)  :: 52 of 289
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:05:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6686715
            Orig. end                         :: 6707798
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP048397.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Zotchev Lab, University of
            Vienna, Austria.
            Annotated using prokka v1.11 from http://www.vicbioinformatics.com.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21083
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="22"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21083
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21083
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11083](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11083)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(965..978)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.38"
                     /tool="antismash"
     misc_feature    complement(995..1010)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.87"
                     /tool="antismash"
     gene            1184..2974
                     /locus_tag="SSPS47_RS29675"
                     /old_locus_tag="SSPS47_30085"
     CDS             1184..2974
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009327013.1"
                     /locus_tag="SSPS47_RS29675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_30085"
                     /product="sensor histidine kinase"
                     /protein_id="WP_164253620.1"
                     /transl_table=11
                     /translation="MVRVEAPMNDQASPTVRALLLSAALMATATAVVVVLVADAARIPV
                     AAYGAVVTVLVTWGAVEIARRGQATRASHVRYGHQVAFLERRIAEHDSQSVRLGKELMP
                     LAIHQLRRGNSPQEVMNVIVDGDERYRELPDSQRALLRAILDIVDDEEAMRESAQRSFV
                     NIARRVQSLVHQQASELREMEEHHGRNPEVFDDLLRIDHGTALIGRLADSVAVLGKARP
                     GRQWPRPVPLFSVLRGAMSRILEYQRVDLHSIAKVAIVGTAVEPLIHACAELLDNATRY
                     SPPQTRVHVTAVEVQTGIAIEIEDGGVSLSEEARTRAERMLAQAQAGVDLNDLGESPRL
                     GMAVVGRLCQMYNLQVSLRQSAYGGVRAVLVVPRDVVTTGPAPGIAHGIGASAMGTGGT
                     ELPEMRRPRTADAAPAAAIGRTPGRGSGAPASNPAPAPAAVPAPRPATGPVRSAPVRAA
                     MEDDVPVVTEWTANGLPQRRSRGRAPLGSHNIVRTPAPQRSNATSAGTPGTTGAPGAPG
                     TSNGTGEAGKPGPGIWLEAFTKAVSGDPHPQGPSTGTTGTTGVTGTTGVTDATGAGDAP
                     PDLPGERGESDDMWGKGDLK"
     gene            2971..3378
                     /locus_tag="SSPS47_RS29680"
                     /old_locus_tag="SSPS47_30090"
     CDS             2971..3378
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018491940.1"
                     /locus_tag="SSPS47_RS29680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_30090"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_164253621.1"
                     /transl_table=11
                     /translation="MIQQRANLDWLLKELADGVPQVQQIVVLSADGLRIARHGGDPDVA
                     DRLAAACAGLQSLAAAVAAEIPMSDGRMRLVVIEVSGGFFYLMEAGTGAYLAVLADETV
                     DAGLVGARMRDMVVRIGAHLTSPPRHDGQTG"
     gene            3375..3746
                     /locus_tag="SSPS47_RS29685"
                     /old_locus_tag="SSPS47_30095"
     CDS             3375..3746
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964953.1"
                     /locus_tag="SSPS47_RS29685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_30095"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_164253622.1"
                     /transl_table=11
                     /translation="MTPPRRERRLPGADVGDPERLYVITGGPDGAERASLDLVTMIVAR
                     GAPSPTVPPEQAAILRLCGAPLSVAELSAYLRLPFSVVTALLTDLLTTDLVESRAPVAR
                     AALPDRSLLEAVMHGLQKL"
     gene            3727..4338
                     /locus_tag="SSPS47_RS29690"
                     /old_locus_tag="SSPS47_30100"
     CDS             3727..4338
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003947184.1"
                     /locus_tag="SSPS47_RS29690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_30100"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_164253623.1"
                     /transl_table=11
                     /translation="MDSRSSDTITGPRSGDVLPTTATSAVKVVIVGGFGVGKTTMVGSV
                     SEIRPLTTEETMTQAGVGVDDNSGVESKTATTVAMDFGRISISEQLVLYLFGTPGQERF
                     WFLWNGLFEGALGAVVLVDTRRLEVSFDVIGRLEERGVPFVVAVNTFPDAPSHPVEALR
                     TALDLPDEVPMVDCDARLRSSSRDVLLTLMRYLHSLALPA"
     gene            4413..>5255
                     /locus_tag="SSPS47_RS29695"
                     /old_locus_tag="SSPS47_30105"
                     /pseudo=""
     CDS             4413..>5255
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015579617.1"
                     /locus_tag="SSPS47_RS29695"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_30105"
                     /product="cytochrome P450"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTTPYSHRPGTDDHAAPPPGCPAHGLVADAFGDHLAPSGLRRLYG
                     PEAERDPMGLYEKLRAEHGSVAPVLLHGDVPAWLVLGHSENLHMTRTPSQFSRDSRRWR
                     AVNDGSVPPDHPLAPIFTWQPICVFADGADHERLRGAVTDSIGRIDHRGVRRFINRYSN
                     RLVNDFCQDGRADLVSRFAEHLPMMVMAQILGMPEEYNERLVESARDMIKGTETAVESN
                     AYVMAALDRLVARRRAAPDEDFASWLVEHPAGLTDAEVAQHLRLVLIAAFETTANLIAN
                     "
     misc_feature    complement(5264..5280)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.47"
                     /tool="antismash"
     misc_feature    5425..5439
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.08"
                     /tool="antismash"
     misc_feature    5427..5443
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.65"
                     /tool="antismash"
     gene            5493..6611
                     /locus_tag="SSPS47_RS29700"
                     /old_locus_tag="SSPS47_30110"
     CDS             5493..6611
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010636347.1"
                     /locus_tag="SSPS47_RS29700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_30110"
                     /product="site-specific integrase"
                     /protein_id="WP_203557829.1"
                     /transl_table=11
                     /translation="MGGNRLAPGAVGLHLVGDLPLLRPDEQVFTAMLDGWRNQQLARNL
                     AFSTIEGREKVVRAFVRHADTFPWAWSPQMVDEWLGDLRSVRHLRRSTLRNYQGSVRSF
                     CSFITDPAYGWAVTCEERFGAHPVQVVHEWNTAVHVEEAEADPSKRAFTRQELQAFFDH
                     ADDQVGRVRGRGRKGWLPAFRDAMLFKTAYAFGLRRNETRMLDSVDFGRNPEGPEFGEY
                     GVLYVRHGKAKKGSPPKRRSVLTVFDWSAEILQQWNEEVRPLFPTAGSGALWPSERSAR
                     VGFSQMNTRFTTYRDALGLDDGLDFHSFRRSYVTHLIEKGMDARFVQEQVGHEHASTTA
                     IYTCVSSDFRTRTLRRALDATMQAALRPARRA"
     gene            6611..6946
                     /locus_tag="SSPS47_RS29705"
                     /old_locus_tag="SSPS47_30115"
     CDS             6611..6946
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007500847.1"
                     /locus_tag="SSPS47_RS29705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_30115"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_164251158.1"
                     /transl_table=11
                     /translation="MKRQVSYQWRLREVMATRGIFAASDLSPLLAERGIELSSVQVWRL
                     VTQTPERLSLPVLAALCDILDVTPTDLIATRAENVAPRRTAASGGADVVDLANTIRPKR
                     ARITPDS"
     gene            7138..8439
                     /locus_tag="SSPS47_RS29710"
                     /old_locus_tag="SSPS47_30120"
     CDS             7138..8439
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010636349.1"
                     /locus_tag="SSPS47_RS29710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_30120"
                     /product="site-specific integrase"
                     /protein_id="WP_239064878.1"
                     /transl_table=11
                     /translation="MAGTAICRDCAGISRDFFCDRCGFEGLLLGGRLCERCTLSDQLTA
                     LLDDGTGCIHPQLIPLHQLLVSLDRPKSRLIWLRNRQVPALLRDLATGTVPLTHDAIQA
                     LPNWRTAAYLRDLLMDSGVLPHLDRRLLLFERWLAQRIATTADTEHARILQHFATWHQL
                     RKLRAKAAKGPLGTSTTQECRQQITQAGAFLVWLAARHVALSACTQTDLDAWHAEKYAT
                     RRPAQAFLRWCMETRRMPRLIIPNHPTTNPHPMGQHQRVTALQRVLADDSTALRVRVAA
                     CLVLLFAQPVSRIVRMTTDDVLRDGQCVTLRLGDPPTPAPEPVADLLLDYLQALPASTP
                     AINQNSPWLFPGRRASQPMNPATLRDALRKLGIPVEKGRTSAIRQLVLQAPAPVIAQAL
                     GYHDKSTTRIANDAGAPWKNYAPGDHNRRSPRLR"
     gene            complement(8460..9071)
                     /locus_tag="SSPS47_RS29715"
                     /old_locus_tag="SSPS47_30125"
     CDS             complement(8460..9071)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019432370.1"
                     /locus_tag="SSPS47_RS29715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_30125"
                     /product="amino acid transporter"
                     /protein_id="WP_164254546.1"
                     /transl_table=11
                     /translation="MTRLRAPFGRWDPASLSEVVARFSGLESCWWVAGGFAIELAVGRR
                     IRSHGDIDVLLLRRDQLVAQQALSGWQWWAADPPGSLRPWALDEVLSLEVHDIWCRPGP
                     DDPWRIQIMIDESCGQEWVSRRDPRVRRPISMLGMTSADGVPFLALDVQLYYKAKTPRP
                     KDEEDFDAALPVLTDQQRSWLVDAISKTYGPHPWIKRLQA"
     gene            <9205..9942
                     /locus_tag="SSPS47_RS29720"
                     /old_locus_tag="SSPS47_30130"
                     /pseudo=""
     CDS             <9205..9942
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018491942.1"
                     /locus_tag="SSPS47_RS29720"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_30130"
                     /product="cytochrome P450"
                     /pseudo=""
                     /transl_table=11
                     /translation="RMVLTDPRFRAQLSGGHMTLPEAVEQTLWDEPPFTTIFGRWAVGD
                     TELGGQRIKAGDALVVGIAAANVDPVVRPDVKASMQGNRAHLAFSGGPHECPGQDIGRA
                     IADTGIDALLLRLPDLQLAVPEADLRWSASLMSRHLQELPVTFAARSPQDVAGPPSATP
                     GHAPRTEWQVESPRPVPAQGASGAFAVPSPARPAGSPSVTTSEAPSAAPSAPPNPAGAI
                     PAQRGPGAPARAWRTVVRWWRGY"
     gene            complement(10001..11083)
                     /locus_tag="SSPS47_RS29725"
                     /old_locus_tag="SSPS47_30135"
     CDS             complement(10001..11083)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="SSPS47_RS29725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_30135"
                     /product="terpene synthase family protein"
                     /protein_id="WP_164253625.1"
                     /sec_met_domain="T1TS (E-value: 5.3e-73, bitscore: 245.5,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTCVEEQVLSQQLPAVPFYCPVEPAVHPGVDVLNDLTVDWMLRQN
                     LDTDERQRKRLAVCDFGGLTAWTMPYGRLEPLTLMAKFHAVLFSLDDGVCDETDATADL
                     MAQETSRILRAVEAPAANSRADSPHAAALRALRTELERYASPQQLRRWTDAMRVYTSGL
                     VWEASWRRSPELPSLNDYITLWMRAIGMAPSTAMIEIVGGFSVRDEELADPRVQALTEM
                     AWTLVSWDNDLYSRNKELLRAGDDLNLIDVLCQELGCEPREALRHAVAMRDRVMVLHGR
                     LGEQVLVDASDELRGYIEGLGQFVRGHLDWASGCPRYWVPSGPAAEPGGWWKPDPSDAG
                     REPLPIPTISWWWEQLAVSD"
     misc_feature    complement(11169..11183)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.43"
                     /tool="antismash"
     gene            complement(11467..13071)
                     /locus_tag="SSPS47_RS29730"
                     /old_locus_tag="SSPS47_30140"
     CDS             complement(11467..13071)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017944278.1"
                     /locus_tag="SSPS47_RS29730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_30140"
                     /product="CAP domain-containing protein"
                     /protein_id="WP_164253626.1"
                     /transl_table=11
                     /translation="MSSPFKTSVVKEAQAGDRSALDRLGHESLPLVHQLVGHALHGHPE
                     VDATARDTVRHALAGLDGLRRPADFRSHLAITAVARIREHADYVYDLTLPRPDFDFVDL
                     MISRLGLSGQHREVAEATRWVDREHHALVALWWLETAGELTRPEVAAALAANSQQVEAR
                     IARMRHELDTARAVVRALSAQPPCVLLEQLVGGWDGVPSPLWRERMARHTYDCTVCSGY
                     AAELAPADTLVAGLALVPVGDRRAPTAASRSGGFGGGAPNSVSSGVSRSVSSDGSRTGA
                     RDALRRDRRAKRRRAVTVTAAVAALLTAGGVAQLVASDRDKDESRASTAVEPEALEPKS
                     AASPSAKSPSPSPSRTSASPSPSPTRSPSKKAAEPSRSAPAPRPSTAGPAPKPDPTPPA
                     DDPKPGGGGGLADQVTTLVNSERSKAGCGPVNANSQLGTAALHHSEDMAAKGYFDHNSP
                     DGKDPGDRITAAGYDWSTYGENIARGQQTATQVMEGWMKSPGHRANILNCAFKEIGVGV
                     HEGSGGPWWTQAFGARG"
     gene            13376..14407
                     /gene="tdh"
                     /locus_tag="SSPS47_RS29735"
                     /old_locus_tag="SSPS47_30145"
     CDS             13376..14407
                     /EC_number="1.1.1.103"
                     /GO_function="GO:0008743 - L-threonine 3-dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006567 - threonine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="tdh"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014153308.1"
                     /locus_tag="SSPS47_RS29735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_30145"
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="WP_164253627.1"
                     /sec_met_domain="ADH_N (E-value: 4.2e-31, bitscore: 105.7,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.9e-23, bitscore:
                     81.6, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKALVKLTAEPGLRLTDVPEPEAGPADVLIKVLRTGICGTDLHIR
                     AWDGWARQAVEAPRVLGHEFVGEVASVGADVQDIAVGDLVSGEGHLVCGKCRNCLAGRR
                     HLCRSTVGLGVGRDGAFAEYVALPASNVWVHRAPVDLDIAAIFDPFGNAVHTALTFPLV
                     GEDVLITGAGPIGIMAAAVARHAGARNVAVTDVSPERLEIARKVGATLALDVSAPGTGI
                     AEAQRRLGLKEGFDIGLEMSGRPEAMRDMVDNMTHGGRIAMLGLPASEFAVDWAKIVTS
                     MITVKGIYGREMYETWYAMTVLLEGGLDLAPVITGSYGYEDFDTAFDEAAKATGGKIIL
                     NWA"
     gene            14483..15664
                     /locus_tag="SSPS47_RS29740"
                     /old_locus_tag="SSPS47_30150"
     CDS             14483..15664
                     /EC_number="2.3.1.29"
                     /GO_function="GO:0008890 - glycine C-acetyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (41-383). E-value:
                     3.1e-72. Score: 235.6. Matches aSDomain:
                     nrpspksdomains_SSPS47_RS29740_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1109: 8-amino-7-oxononanoate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007494053.1"
                     /locus_tag="SSPS47_RS29740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_30150"
                     /product="glycine C-acetyltransferase"
                     /protein_id="WP_164253628.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 3.6e-70, bitscore:
                     235.6, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYASVRDDLRATLDEIRDAGLFKPERVINTPQNASVSVASGDVLN
                     FCANNYLGLADHPDVVAAAKDALDRWGYGMASVRFICGTQEVHKELERRLSSFLGQEDT
                     ILYSSCFDANGGVFETLLGPEDAVISDALNHASIIDGVRLSKARRLRYANRDLAELEAR
                     LKESQDARRRLVVTDGVFSMDGYVAPLAEICDLADRYDAMVMVDDSHAVGFVGPGGRGT
                     PELHGVMDRVDIITGTLGKALGGASGGYVAARCEIVALLRQRSRPYLFSNSLAPVIAAA
                     SIKVLDLLESADGLRERLKANTALFRTQMTAAGFEILPGDHAIAPVMIGDAAEAGRMAE
                     LLLERGVYVIGFSYPVVPMGQARIRVQLSAAHSTEDVRRAVAAFVDARDALKG"
     aSDomain        14606..15631
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SSPS47_RS29740_Aminotran_1_2.1"
                     /evalue="3.10E-72"
                     /label="SSPS47_RS29740_Aminotran_1_2.1"
                     /locus_tag="SSPS47_RS29740"
                     /protein_end="383"
                     /protein_start="41"
                     /score="235.6"
                     /tool="antismash"
                     /translation="DVLNFCANNYLGLADHPDVVAAAKDALDRWGYGMASVRFICGTQE
                     VHKELERRLSSFLGQEDTILYSSCFDANGGVFETLLGPEDAVISDALNHASIIDGVRLS
                     KARRLRYANRDLAELEARLKESQDARRRLVVTDGVFSMDGYVAPLAEICDLADRYDAMV
                     MVDDSHAVGFVGPGGRGTPELHGVMDRVDIITGTLGKALGGASGGYVAARCEIVALLRQ
                     RSRPYLFSNSLAPVIAAASIKVLDLLESADGLRERLKANTALFRTQMTAAGFEILPGDH
                     AIAPVMIGDAAEAGRMAELLLERGVYVIGFSYPVVPMGQARIRVQLSAAHSTEDVRRAV
                     AA"
     gene            15755..16669
                     /locus_tag="SSPS47_RS29745"
                     /old_locus_tag="SSPS47_30155"
     CDS             15755..16669
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017948338.1"
                     /locus_tag="SSPS47_RS29745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_30155"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_164253629.1"
                     /transl_table=11
                     /translation="MIDPRRLRILRAVADHRTVTAAAAALYLTPSAVSQQLAALEQETG
                     HALLTRSGRGVRLTAAGEILLTHAHEVLAQLERAEAELAAYAGGAAGEVTVAAFATGIA
                     EVLAPAVAHLADSDPGIRVRVRDSEGDESLPLLLDGQADVALAVEYRGAPTEDDPRLSR
                     VPLYAEPFDAVLPEGHPLRHEIEVPLAGLSDSDWISPYPGNPCHEVMRLACELAGFEPR
                     LVHSSDDFRAVVALAGAGAGVALVPRSALRGMELKGTVVRPVSGPPATRRVFAAVRRGA
                     EHHPLIRPVLDALTESASGLTTG"
     gene            16996..17730
                     /locus_tag="SSPS47_RS29750"
                     /old_locus_tag="SSPS47_30160"
     CDS             16996..17730
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004992180.1"
                     /locus_tag="SSPS47_RS29750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_30160"
                     /product="D-Ala-D-Ala carboxypeptidase family
                     metallohydrolase"
                     /protein_id="WP_239065107.1"
                     /transl_table=11
                     /translation="MFRSALHTSLALVMISAGAIVGATVTAGPAHAASDCGQPITGLPL
                     QQGSQGTSVERLQIRVAGFVDSGEVLSADGVYGGRTKEAVRKFQAQYGLQADGIAGSRT
                     VDKIYALQDSDCTPIHFSYAEWNKCNSTWSGGAVSASAAKANARRSMWKLEALRQKLGG
                     NPIQISSGFRSNSCNEAVGGVSGSRHTYGDAADMPGTQTWRCKLHNGAKSSGFREILGQ
                     GFTGHNDHTHVGMTGSRQWHGC"
     gene            17756..19075
                     /locus_tag="SSPS47_RS29755"
                     /old_locus_tag="SSPS47_30165"
     CDS             17756..19075
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024808.4"
                     /locus_tag="SSPS47_RS29755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_30165"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_164253630.1"
                     /transl_table=11
                     /translation="MSRRSFLGAGAFTVLGAGAAGCDSGAGGDTTATEPLLALVPEDGT
                     TRIHAATVSRFNKSPAKARAEATAELRDAPASSYDRVLDRALDGDRGPDLLFTWSAGAI
                     RVSAEEHRLVDLYNLTEDYPEFGERLLPGVLEGCAVNHRPFGIPVRGTRPVVLFYHRAL
                     FADLGLQPPATWSDLKKAGARLRAANVVPVALAGSDPAAAARWLEYLVERIGGPGVADR
                     VRSGDHGAWSDRTVLRAAQEVISLLDSGSFGDGVGGGEAATDSEAAALLAGGRAGLLLA
                     ESAQHAELARKFPVFTDKHLGWVPFPTVERGRGKPESLLGTPAGYLTVSERTENRLAAV
                     ALLKEFTGTEHSEALLRAGDVPATTTAAKLLDHAPNPEFTRFQYELVRKAPNYTVSWER
                     AVHPAWRDPMLTEVGDLFAGRSTAREFSEAMRRVELPVAR"
     gene            complement(19110..20228)
                     /locus_tag="SSPS47_RS29760"
                     /old_locus_tag="SSPS47_30170"
     CDS             complement(19110..20228)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SSPS47_RS29760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SSPS47_30170"
                     /product="hypothetical protein"
                     /protein_id="WP_164253631.1"
                     /transl_table=11
                     /translation="MSDAPNDDALYAALPDADLLKALAPYATRGGGTVADAGRLRDVTR
                     RQLVRCEVVRFTERRGETQRTAFGTKDLSALPLYEGAIADHRLTPPEEPGRVTLLRAHS
                     HRLVPCPCDNGTMRCASCCGSGRHDCTCRNEPPACGLCLDVAPCTECEKSGGRRTRTVK
                     ARPAATGPRATAPGAPRITCALCGTSEAACRGCSGRGRVRCPHCEGRGRETCARCSGRG
                     VGPHDVCGGKGSLTHWVEGTVAYTHEKASLSLPAPDWPDKVRERLAAARWRRQEVPADG
                     AVPSGVHGTHRAAVANHLAHRNAELSRRVTLETCPLARVELTGDPNRVFHVFPGDRSLE
                     VVATLSNRLKRRLIAAGAVIVIVVVLIVRLVA"
ORIGIN
        1 ttcgtgttcc ggatgccgaa ggccgtgccg cggtcgccgg ggaaccgggc gtcgacggtc
       61 gagcagtgcc gcgcgaacgc cggcgacttc agccccgcgc ggccgaacac cgcgaggtcg
      121 tacgccgacg acacctgccc gggctcgtcg tagccgtccg gcgagaccac gcgggtgtcg
      181 cgggcgccca gctcctccgc cttggcctgc atctgtctga tggtcgattt ccagccgccg
      241 ttcatcccgg cgaggacccg cacggcgtcg ttgcccgagc tgaggaagac accccgccac
      301 agatcggcca cgtcgtacgt ctgcccggcg gtgattccca ccatgctgct gccggcgccg
      361 atccccgcca gatcggcccg ggtcacgctg tgccgggtgc ccgaggggat ccggggcagc
      421 gcggtgacgg cgaacagggt cttgagcgtg ctggcgggcg gcagcgcgcg gtgcgcgttg
      481 tgggcggcga gcaccgcgcc cgtgcgcgcg tcggcgacga cccaggagag ggcggagaca
      541 tccttgggag gcgcgggcgc gcccgatgtc gcgcgcacgt gggtgccggg ccggtacagc
      601 agggaggggt cggcccgcga gagcgcgtcg gcggtggagg ccgcggcgct cgcggcggtg
      661 gccatgggta cggacgccgc cgccggaaca acggccagca gaccggccag accggtggtc
      721 agggccatgg agcgggccaa cgagggatgc gggagccatc tgatgatcat tcagtcaccg
      781 tagaaacggg cgccgccccg cgcacggccg cctgagccga ccggaggtat ccccgtccga
      841 cgccgccccc gcctccttcg gcgtgtcggc gagccttgcg ggcgtggccg acggggcggg
      901 tccggccggt cggtcccccc gcgctcgcca agggtacaag gcgccgcaat tcgaacaggt
      961 gtcgtcactg agcgtgccgt tcgcgcggcg ctccgtgcaa aacgcgcgag tctatgcctg
     1021 ccgggccggt ccccgcacgg ggttggtgaa tatgccgttg agcactttcg cccgcactag
     1081 gctctcgcgg agcgcaccga gttgatacgg aatcaggcgc ttgttcccat ctgccgcaat
     1141 agtttcgaat acccgaccct gaatcgatcg ccagagggct tacatggttc gtgttgaagc
     1201 accgatgaat gatcaagcgt caccaaccgt tcgcgcgctt ctgctctccg ccgccctgat
     1261 ggcgacggcg acggccgtcg tcgtggtcct cgtcgccgac gccgcccgga ttccggtcgc
     1321 ggcgtacggc gcggtcgtca ccgtcctcgt cacctggggg gccgtggaga tcgcccggcg
     1381 gggccaggcg acgcgcgcgt cgcatgtgcg gtacgggcac caagtcgcct tcctggaaag
     1441 gcgtatcgcc gagcacgaca gccagagcgt gcgcctcggc aaggaactga tgccgctcgc
     1501 catccaccag ctccgccggg ggaactcgcc ccaggaggtc atgaacgtca tcgtcgacgg
     1561 cgacgagcgc taccgcgaac tccccgactc gcagcgcgcg ttgctccgcg cgatcctcga
     1621 catcgtcgac gacgaggagg ccatgcgtga gtccgcgcag cgctccttcg tcaacatcgc
     1681 ccgacgcgtc cagtccctcg tgcaccaaca ggccagcgaa ctgcgcgaga tggaggagca
     1741 ccacggccgc aatcccgagg tcttcgacga cctgctgcgc atcgaccacg gcaccgccct
     1801 catcgggcgg ctcgccgaca gtgtcgccgt actcggcaag gcccgtcccg gacgccaatg
     1861 gccccggccc gtaccgctgt tcagcgtgct gcgtggtgcg atgtcccgga tcctggagta
     1921 ccagcgagtc gatctgcact cgatcgccaa ggtcgccatc gtcggtacgg cggtcgagcc
     1981 gctgatccac gcgtgcgccg aactcctcga caacgccacc cgttactcgc ccccgcagac
     2041 gcgcgtccac gtgaccgccg tcgaggtgca gaccggtatc gcgatcgaga tcgaggacgg
     2101 cggcgtcagc ctcagcgaag aggcacggac gcgggcggag cggatgctcg cgcaggcgca
     2161 ggccggtgtc gatctcaacg atctcggtga gagcccgcgg ctcggcatgg ccgtcgtcgg
     2221 ccggctctgc cagatgtaca acctccaggt ctcgctgagg cagtccgcgt acggaggcgt
     2281 gcgcgccgtc ctcgtcgtac cgcgcgacgt ggtcaccaca gggcccgcgc ccggtatcgc
     2341 ccacggcatc ggcgcgtccg cgatgggcac cggcggcacc gagctgcccg agatgcgccg
     2401 cccgcgcacc gcggacgccg cgcctgccgc cgccatcggc cgcacgccgg gccgggggag
     2461 cggggccccg gcctcgaacc ccgcgcccgc cccggccgcc gttcccgcgc cccgcccggc
     2521 caccggcccg gtgcggtcgg cgccggtcag ggccgccatg gaggacgacg tccccgtcgt
     2581 caccgagtgg acggcgaacg gccttccgca gcgccgcagc cgtggcaggg ccccgctggg
     2641 ctcgcacaac atcgtgcgga caccggcgcc gcagcgttcg aacgcgacct ccgccggtac
     2701 tccggggacg accggcgctc cgggcgcgcc cggcacctct aacggcaccg gggaagcggg
     2761 gaaacccggc cccggcatct ggctcgaagc attcaccaag gcggtcagcg gcgacccgca
     2821 cccgcagggg ccgtcgaccg gcaccacggg cactaccggc gtcacaggca cgacaggcgt
     2881 cacagatgcg acaggcgcgg gcgacgcgcc gccggacctg cccggcgagc gcggggaatc
     2941 agacgacatg tggggcaagg gggacctgaa gtgatccagc agcgtgccaa cttggactgg
     3001 ctgctcaagg agctcgcgga cggcgttccg caggtccagc agatcgtcgt gctctccgcc
     3061 gacggactgc ggatcgccag acacggtgga gaccccgacg tcgccgaccg tctcgccgcc
     3121 gcctgcgcgg gacttcagag cctcgccgcc gccgtcgccg ccgaaatccc gatgagcgac
     3181 ggccggatga ggctcgtcgt catcgaagtg agcggcggat tcttctactt gatggaagcg
     3241 ggtaccggcg cctacctcgc cgtactcgcc gacgagacgg tggacgccgg actcgtcggc
     3301 gcccggatgc gtgacatggt cgtccggatc ggcgcccatc tgacgagtcc gccgcggcac
     3361 gacgggcaga ccggatgact cctccccgac gagaacgcag gctgcccggg gcggacgtgg
     3421 gggaccccga acggctgtac gtgatcacgg gtggcccgga cggcgccgag cgcgcctcgc
     3481 tcgacctcgt caccatgatc gtggctcgcg gggccccctc gccgacggtg ccgcccgaac
     3541 aggccgccat cctgcggctc tgcggggcgc cgctgtccgt ggccgagctc tcggcgtacc
     3601 tcaggctgcc gttcagcgtg gtgacggcgc tgctgaccga cctcctcacg accgatctgg
     3661 tcgagtcccg agcgcccgtc gcccgcgccg cactccccga caggtccctt ctcgaagcgg
     3721 tgatgcatgg actccagaag ctctgacacg atcacaggac ccaggagcgg ggacgtactt
     3781 cccaccacgg cgacatccgc ggtgaaggtc gtgatcgtgg gcggattcgg ggtcggcaag
     3841 accaccatgg tcgggtcggt gagcgagatc cgcccgctca ccaccgagga gaccatgacc
     3901 caggccggcg tcggcgtgga cgacaactcc ggggtcgaga gcaagaccgc caccaccgtc
     3961 gccatggact tcggccggat cagcatcagc gagcaactgg tgctctacct cttcggcacc
     4021 cccggccagg aacgcttctg gttcctctgg aacgggctct tcgagggggc gctcggcgcc
     4081 gtcgtcctcg tcgacacccg gcgcctcgaa gtcagcttcg acgtgatcgg gcggctggag
     4141 gagcgcggcg tgccgttcgt cgtcgcggtc aacaccttcc ccgacgcacc gagccatccc
     4201 gtcgaggcgc tgcgcaccgc gctcgacctg ccggacgagg tgccgatggt cgactgcgac
     4261 gcgcggctgc ggtcgtcgag ccgcgacgtc ctgctgaccc tcatgcgcta tctgcactcg
     4321 ctggcgctgc cggcctgaac ccctcccggc ccgaacccac ttgaggcccg gccccctacc
     4381 ggcccgatcc ccctcccatc cctggagtga ccgtgacaac gccctattcg caccggccgg
     4441 gaacggacga ccacgccgca ccgccgccgg gctgcccggc ccacggactg gtcgccgacg
     4501 ccttcggcga ccacctggcg ccctccgggc tgcgacggct ctacggcccc gaggccgaga
     4561 gggaccccat gggcctgtac gagaagctgc gcgccgagca cggctcggtg gcaccggtcc
     4621 tgctgcacgg tgacgtaccg gcctggctgg ttctcggcca cagcgagaac ctgcacatga
     4681 cgcgcacccc gtcccagttc tcgcgggact cccgacgctg gcgcgcggtc aacgacggca
     4741 gcgtgccgcc cgaccacccc ctcgcgccca tcttcacctg gcagcccatc tgcgtcttcg
     4801 cggacggcgc cgaccacgag cggctgcggg gcgccgtcac cgactcgatc ggccggatcg
     4861 accaccgggg cgtacggcgt ttcatcaacc gctacagcaa ccggctcgtc aacgacttct
     4921 gccaggacgg cagggccgac ctcgtcagcc gtttcgccga gcacctgccg atgatggtga
     4981 tggcccagat cctcggcatg cccgaggagt acaacgaacg gctggtcgag tcggcccgcg
     5041 acatgatcaa gggcaccgag acggccgtcg agagcaacgc gtatgtgatg gcggccctgg
     5101 accggctggt ggcgcgccgc cgggcggcgc ccgacgagga cttcgcgagc tggctcgtcg
     5161 agcacccggc cgggctcacg gacgcggagg tcgcccagca tctgcgactg gtgctcatcg
     5221 cggcgttcga gaccacggcc aacctcatcg ccaatgtgct aagtggccgc aatttcatca
     5281 gatgcaacac tgcggttggg gtgcatatca acagccgcct tccccctatg tcctggtcag
     5341 caccctgtgc gggttcggtg tggatggctc gccgggccgc ttgagatgcg gcgaatgcga
     5401 gccggcatgc cttctgagct gggaacttgt caggtgatta catctgatga aagattcctt
     5461 cgtctgatgt aggcggcgga gggtagtcat tcgtgggtgg gaacaggctc gcgccggggg
     5521 ctgttgggct gcacctggta ggtgacctgc cgctgctgcg gccggacgag caggtgttca
     5581 cggcgatgct ggacggctgg cgcaaccagc agctcgcgcg gaacctggcg ttctccacga
     5641 tcgagggccg ggagaaggtg gtacgcgcct tcgtccggca cgcggacacg ttcccctggg
     5701 cctggtcgcc gcagatggtc gacgagtggc tgggcgacct gcggtcggta cggcacctgc
     5761 gccgttccac actccgcaac taccagggat cggtccggtc cttctgctcc ttcatcaccg
     5821 atcccgccta cggatgggcg gtgacctgcg aggagcgttt cggcgcccac ccggtgcagg
     5881 tggtgcacga gtggaacacc gcggtgcacg tggaggaagc cgaggcagac cccagtaaac
     5941 gggccttcac ccggcaggag ttgcaggcgt tcttcgacca cgccgacgac caggtcggca
     6001 gggtccgcgg ccggggccgc aagggctggc tgcccgcatt ccgcgacgcg atgctgttca
     6061 agaccgcgta cgccttcggc ctgcgccgca acgagacgcg gatgctggac tcggtcgact
     6121 tcggacgcaa ccccgaaggt cctgagttcg gcgagtacgg cgtcctctac gtccgccacg
     6181 ggaaggcgaa gaagggctcg ccgcccaaac gccgcagtgt gctgaccgtc ttcgactggt
     6241 cggcggagat cctccagcag tggaacgagg aggtacgtcc gctgtttccc accgccggct
     6301 ccggggctct gtggccgtcg gagcgatcgg cccgggtcgg cttctcccag atgaacaccc
     6361 ggttcaccac ctaccgggac gccctcggcc tggacgacgg actcgacttc cactccttcc
     6421 gcaggtccta cgtcacccac ctgatcgaga agggcatgga cgcccggttc gtccaggaac
     6481 aggtcgggca cgaacacgca tccacgaccg cgatctacac atgcgtgtcc tccgacttcc
     6541 gcacccgcac cctgcgcaga gcgttggacg cgacgatgca ggccgctctg cggccggcga
     6601 ggagggcttg atgaaacgcc aggtcagcta ccagtggcga ctgcgcgagg tgatggccac
     6661 ccgcggcatc ttcgccgcct ccgacctctc cccgctgctc gccgaacgcg gcatcgagct
     6721 gtcctcggtc caggtctggc gcctggtcac ccagactccc gaacggctct ccctgccggt
     6781 cctggccgcg ctctgcgaca tcctcgacgt cacccccacc gacctgatcg ccacccgggc
     6841 cgagaacgtc gccccgcgcc gcaccgccgc ctccggcggc gccgacgtcg tggacctggc
     6901 caacaccatc cggcccaagc gcgcccggat cacccccgac tcgtgagccc ggcctacgac
     6961 agccgcgaga aatacgagcg gtggcacata cgcacctgcg cacgctgcgg ccgccgcgca
     7021 gccaagtccg cgaactggtc agacggacct atctgccgca cctgctatga acgggccacg
     7081 cgggaccgag gccgctgccc cggctgcaaa accgagcggc tgcttcccgg ccgcaacgtg
     7141 gcgggaaccg cgatctgccg ggattgcgca ggcatcagcc gcgacttctt ctgcgaccgc
     7201 tgcggcttcg agggcctact cctgggcgga cggctctgcg aacgctgcac cctctccgac
     7261 cagctcaccg ccctcctgga cgacggcacc ggctgcatcc acccacagtt gatcccgctg
     7321 caccagcttc tggtgagcct ggaccgtccg aagagtcggc ttatctggct ccgcaaccgg
     7381 caagtcccgg cactcctgcg agacctcgcc accggaacag tgccactcac acacgacgcc
     7441 atccaggccc tgccgaactg gcggaccgcc gcctacctgc gcgacctgct catggacagc
     7501 ggcgtcctgc ctcacctcga ccggcgactc cttctgttcg agcggtggct cgcccagcga
     7561 atcgccacca ccgccgacac cgaacacgcc cgcatactcc agcacttcgc cacctggcac
     7621 cagcttcgca agctccgagc caaggcggcc aagggcccgt tgggcacgag tacgacgcag
     7681 gaatgccgcc agcagatcac ccaggctggt gccttcctgg tctggctcgc cgcccggcac
     7741 gtcgcgctga gcgcctgcac ccagaccgat ctcgatgcct ggcacgcgga gaagtacgcc
     7801 acccggcgac ctgcccaggc gttcttgcga tggtgcatgg agacccgccg gatgccgcgg
     7861 ctgatcatcc cgaaccaccc gaccaccaac ccccacccga tgggccaaca ccagcgcgtc
     7921 accgccctgc aacgggtcct cgccgacgac agcaccgcgc tgagagtccg ggtcgcggcc
     7981 tgtctggtcc tgctgttcgc ccaacccgtc agccgcatcg ttcgcatgac caccgacgac
     8041 gttctccgcg acggccagtg cgtcacactc cgccttggcg acccgcccac tccagcccct
     8101 gagccggtgg ccgacctcct gctcgactac ctccaagcgc tgcccgccag cacccccgcc
     8161 atcaaccaga actcgccctg gctgttcccc ggtcgccgag cgagccagcc catgaacccc
     8221 gccaccctgc gcgacgcact acgaaaactc ggcatccctg tcgagaaagg ccgcacctcg
     8281 gccattcgcc agctcgtcct ccaggccccg gcgcccgtca tcgcccaggc actgggctac
     8341 cacgacaaga gcaccacccg catcgccaac gacgccggag ccccctggaa gaactacgca
     8401 cccggcgacc acaaccggcg atctccacgg ctccggtgag gcaccggccg accgtgagat
     8461 tacgcctgca ggcgcttgat ccaagggtga ggtccgtacg tcttggagat cgcatcgacg
     8521 agccagcttc gctgctgatc cgtgagcacg ggcagcgcag cgtcgaagtc ctcttcgtcc
     8581 ttgggccgag gtgtcttggc tttgtagtag agctgcacgt ccagggcgag aaagggaaca
     8641 ccgtcagccg aggtcatccc cagcatgctg atcggcctac gcacccgggg gtcacgccgt
     8701 gacacccatt cctggccgca ggactcgtcg atcatgatct ggatacgcca gggatcgtcg
     8761 ggcccgggcc ggcaccagat gtcgtgaact tccagcgaca agacctcgtc caacgcccac
     8821 ggacgcaggc ttcccggtgg atcggcggcc caccattgcc agcccgacag agcctgctgg
     8881 gccacgagct gatcacgccg cagcaacagg acatcgatgt ccccatggct ccggattcgg
     8941 cggcccaccg cgagctcgat cgcgaagccc ccagccaccc accagcagga ctccaagccg
     9001 gagaacctcg cgacaacctc gctcagagag gcgggatccc acctgccaaa cggagcccgg
     9061 agacgtgtca tgccgctcat tctcccgtgg ctgcccttga gccgacgcac accactgttg
     9121 atcacgagca gtaacagaca cgagagccga aaggccgtca ggttcaggaa caccgactac
     9181 tcgataaacg actcttacca gtcccgcatg gtcctcaccg acccgcggtt ccgtgcccag
     9241 ctcagcggtg gtcatatgac gctccccgag gcggtcgagc agacgctctg ggacgagccg
     9301 ccgttcacca ccatcttcgg ccggtgggcg gtcggcgaca cggagctggg cgggcagcgg
     9361 atcaaggcgg gtgacgcgct ggtcgtcggg atcgccgcgg ccaacgtcga cccggtggta
     9421 cggccggacg tgaaggcctc catgcagggc aaccgcgccc atctggcctt cagcggcggg
     9481 ccgcacgaat gcccgggtca ggacatcggg cgcgcgatcg ccgacacggg gatcgacgcg
     9541 ctgctgctac gactgcccga ccttcaactg gccgtgccgg aggcggactt gcgctggtcg
     9601 gcgtcgctca tgtcacggca cctccaggag ctgccggtga cgttcgccgc gcgttcgccg
     9661 caggacgtcg ccggaccgcc ctcggccacg ccggggcacg cgccgcgcac cgagtggcag
     9721 gtggagtcgc cgcggccggt gcctgcgcag ggcgcatccg gcgccttcgc cgtaccgtcg
     9781 ccggcacgcc ccgccgggtc cccgtcggtc accacgtccg aggcgccgtc cgccgccccg
     9841 tccgctccgc cgaatccggc cggggcgatc ccggcgcagc gcgggcccgg cgcgccggcg
     9901 cgtgcgtggc ggaccgtggt gcgctggtgg cggggttact gagccgggtc tccggcggat
     9961 gtgggcggct gaggcctggt gagatgggag cggccggagg tcagtcgctg acggccagct
    10021 gctcccacca ccaggagatc gtggggatcg gcagcggctc ccggccggcg tcggaggggt
    10081 cgggcttcca ccagccgccc ggctccgccg ccggacccga cggcacccag tagcgcggac
    10141 agcccgacgc ccagtcgaga tggccccgca cgaactgccc caacccctcg atgtagccgc
    10201 gcagttcgtc gctcgcgtcc acgagcacct gctcgccgag ccggccgtgc agcaccatca
    10261 cccggtcccg catcgccacc gcgtgcctca gcgcctcgcg cggctcgcag cccagttcct
    10321 ggcagagcac gtcgatcaga ttgagatcgt cgcccgcccg cagcagttcc ttgttccggg
    10381 agtagaggtc gttgtcccag ctgaccagcg tccaggccat ctcggtgagc gcctggacgc
    10441 gcgggtcggc caactcctcg tcccgtacgg agaatccgcc gacaatctcg atcatcgccg
    10501 tggacggcgc catccctatg gcccgcatcc acagggtgat gtagtcgttc agtgacggca
    10561 gttcggggct ccggcgccag gacgcctccc acacgagacc cgaggtgtac acccgcatgg
    10621 cgtccgtcca gcggcgcagc tgctgcgggg acgcgtaccg ctccagctcc gtccgcaggg
    10681 cgcgcagcgc ggcggcgtgc ggggagtcgg cgcgggagtt ggcggccggg gcctcgaccg
    10741 cgcgcaggat gcgggaggtc tcctgtgcca tcaggtcggc cgtggcgtcc gtctcgtcgc
    10801 agacaccgtc gtcgagcgag aagagcacgg cgtggaactt ggccatcagg gtgaggggtt
    10861 cgagtctccc gtacggcatc gtccaggcgg tgagtccgcc gaagtcacag acggcgaggc
    10921 gcttgcgctg ccgctcgtcg gtgtccagat tctgacgcag catccagtcc acggtcaggt
    10981 cgttgaggac gtcgacgccg ggatgtacgg ccggttccac cgggcagtag aacggcacgg
    11041 ccgggagctg ctgggacagc acctgttcct cgacgcacgt catgaccggc ctcctgggaa
    11101 agctgtgggc gcagggcggg ttcggtgaga atctggtgcg gtgcggtgtg aggcggcggt
    11161 tgtacgagtg gagcgtatat gcccatgacg gttcgtcaac aacagggcaa ctgatccgtt
    11221 cgtggccgga tttgagcatg tgtggagtgg ccgggaccat tcggagcggc cgtccggccg
    11281 ggcccccacg tcagggccgt accggcgtta ccgcccgccg aggggagcga tcggttccgg
    11341 tggcgcccgc tcgaccggat cgatcctgac tgagaacaca ctgatcgtga tccgtacgtc
    11401 acggtcaggt ggccgggcgg gacgaagtgc gtgggctctg tgagcccctc gccactcgcc
    11461 ccgccgtcag ccgcgcgcgc cgaacgcctg ggtccaccac ggcccgccgg acccctcatg
    11521 gacgccgaca ccgatctcct tgaaagcgca gttcagtatg ttggcccggt ggccggggct
    11581 cttcatccag ccctccatca cctgggtggc cgtctgctgg ccccgcgcga tgttctcgcc
    11641 gtaggtggac cagtcgtagc ccgccgccgt gatgcggtcg ccggggtcct tgccgtccgg
    11701 actgttgtgg tcgaagtagc ccttggccgc catgtcctcg gagtggtgca gcgcggcggt
    11761 gcccaactgt gagttggcat tgaccgggcc gcaaccggcc ttggaacgct cggagttgac
    11821 gagggtggtg acctggtcgg cgaggccgcc gccaccgccc ggcttggggt cgtccgccgg
    11881 cggtgtcgga tcgggcttgg gggccggacc ggcggtggag ggacgcgggg cgggagccga
    11941 cctgctcggc tcggccgcct tcttggacgg cgaacgggtc ggtgagggcg acgggctcgc
    12001 gctggtgcgc gagggggagg ggctggggga cttggcgctg gggctcgccg cggacttggg
    12061 ctccagcgcc tccggttcga cggcggtcga cgcgcgtgac tcgtccttgt cccggtcgct
    12121 cgcgacgagc tgggcgacgc caccggcggt gagcagcgcg gcgacggccg cggtcacggt
    12181 gacggcgcgg cgccgcttcg cccgccggtc gcggcgcagg gcgtccctgg cgccggtacg
    12241 actcccgtcg ctcgaaacac tcctcgaaac gccgcttgaa acgctgttcg gagcgccgcc
    12301 gccgaagcca ccgctccgcg aggcggcggt cggagcccgg cggtcgccca ccggcaccag
    12361 cgcgagaccg gccaccaggg tgtcggcggg cgccagttcg gccgcgtacc cggagcagac
    12421 cgtgcagtcg tacgtgtgcc gggccatgcg ctcgcgccag agcggggacg gtacgccgtc
    12481 ccagccgccg acgagttgtt ccagcaggac gcacggcggc tgcgccgaca gcgcgcggac
    12541 gaccgcgcga gcggtgtcca gctcgtgccg cattcgcgcg atccgcgctt ccacctgctg
    12601 ggagttggcg gccagggcgg cggcgacctc gggccgggtg agttcaccgg cggtctccag
    12661 ccaccacagt gccacgagcg cgtggtgttc ccggtcgacc cagcgcgtgg cctcggcgac
    12721 ctcccggtgc tggccggaga gcccgagacg gctgatcatc agatcgacga agtcgaagtc
    12781 ggggcggggg agggtgaggt cgtacacgta gtccgcgtgc tcacggatcc gggcgaccgc
    12841 ggtgatggcc aggtgcgagc ggaagtccgc cgggcggcgc agcccgtcga gaccggcgag
    12901 tgcgtggcgc accgtgtcgc gcgccgtcgc gtccacctcc ggatggccgt gcagggcgtg
    12961 gccgacgagc tgatggacaa gcggcagcga ctcatggccg agccggtcga gcgccgaccg
    13021 gtccccggcc tgcgcctcct tgaccaccga ggtcttgaac ggactgctca cgctgtctca
    13081 ctcccactcg ttactcgcgg tgggcaccga tggtaagggg aacggcgggc ccgcaccccc
    13141 ttgatggcgc acgcggcgcc gcacaagtgg gcgaattcat atccggccac ccgtccggat
    13201 cctgacggac tcctgttcgg cgtgaagctc agctgtcgcc ccgcttaaga aatcctcgat
    13261 ggactgaacg gtcacggcgg cggcagattg gtgccgacac cgatcggtgc cgctcgcgtc
    13321 acgcacccgc gtgcctccgc gtgtccgcgc acccgcaccg cctggagccg ccccgatgaa
    13381 ggcacttgtg aagctgacgg ccgagccggg gctccggctc accgatgtgc ccgagccgga
    13441 ggccggcccc gcggacgtac tcatcaaggt cctgcgcacc ggcatctgcg gcaccgatct
    13501 gcacatccgc gcgtgggacg gctgggcccg gcaggcggtc gaggcgccgc gtgtcctcgg
    13561 ccacgagttc gtcggcgagg tcgcgtccgt cggcgccgac gtccaggaca tcgccgtcgg
    13621 cgatctcgtg agcggcgaag ggcatctggt ctgcggcaaa tgtcgtaact gtctggccgg
    13681 gcggaggcat ctgtgccgca gcacggtcgg actcggcgtc ggccgtgacg gcgctttcgc
    13741 cgagtacgtc gcgctgcccg cgtcgaacgt atgggtccac cgcgcaccgg tggacctcga
    13801 catcgcggcc atcttcgacc cgttcggcaa cgccgtgcac accgcgctca ccttccccct
    13861 ggtcggcgag gacgtgctga tcaccggcgc cggcccgatc ggcatcatgg cggcggccgt
    13921 cgcccggcac gcgggcgcgc gcaacgtcgc cgtcaccgac gtcagccccg agcgcctgga
    13981 gatcgcccgc aaggtcggcg ccacgctcgc gctcgacgtc tcggcccccg gcaccggcat
    14041 cgccgaggca cagcgacggc tcggtctcaa ggaaggcttc gacatcggcc tggagatgtc
    14101 cggccgcccc gaggcgatgc gcgacatggt cgacaacatg acgcacggcg gccggatcgc
    14161 catgctgggc ctgcccgcct ccgagttcgc ggtggactgg gcgaagatcg tgacctcgat
    14221 gatcacggtg aagggcatct acggccgcga gatgtacgag acgtggtacg cgatgacggt
    14281 gctgctcgaa ggcggtctcg acctcgcgcc cgtcatcacc ggcagctacg gctacgagga
    14341 cttcgacacc gccttcgacg aggcggccaa ggccaccggc ggaaagatca tcctcaactg
    14401 ggcctgatcg cgccgggccc gatcctcgtg ggcccgccca gcacccctcg ccccgacaca
    14461 ctcttcccac cgggagcccc gtatgtacgc gtccgtccgc gacgacctcc gcgccaccct
    14521 cgacgagatc cgcgacgccg gtctcttcaa gcccgagcgc gtgatcaaca ccccgcagaa
    14581 cgcctccgtc tccgtcgcct ccggtgacgt cctcaacttc tgcgccaaca actacctcgg
    14641 cctcgccgac caccccgacg tcgtcgccgc ggccaaggac gcgctcgacc ggtggggcta
    14701 cggcatggcc tccgtacgct tcatctgcgg cacccaggag gtccacaagg agctggagcg
    14761 gcggctctcc tcgttcctcg gccaggagga cacgatcctc tactcctcct gcttcgacgc
    14821 caacggcggt gtcttcgaga cccttctcgg ccccgaggac gcggtcatct ccgacgcgct
    14881 caaccacgcc agcatcatcg acggcgtccg gctgtccaag gcccgccgac tgcgctacgc
    14941 caaccgtgac ctcgccgagc tcgaagcgcg cctcaaggag tcgcaggacg cgcgccgccg
    15001 tctcgtcgtc accgacggcg tcttctccat ggacggctac gtcgcgcccc tcgccgagat
    15061 ctgcgacctc gccgaccgct acgacgccat ggtgatggtc gacgactcgc acgccgtcgg
    15121 cttcgtcggc cccggcggcc ggggcacccc cgaactgcac ggcgtgatgg accgcgtcga
    15181 catcatcacc ggcacgctcg gcaaggcact cggcggcgcg tccggcggct acgtcgccgc
    15241 gcgctgcgag atcgtcgccc tgctgcgcca gcggtcgcgc ccgtacctct tctccaactc
    15301 cctcgccccg gtcatcgccg cggcctcgat caaggttctc gacctgctgg agagcgccga
    15361 cgggctccgc gagcggctga aggcgaacac ggccctcttc cgtacgcaga tgacggcggc
    15421 cggattcgag atcctgcccg gtgaccacgc catcgccccc gtcatgatcg gcgacgccgc
    15481 cgaggccggg cggatggcgg agctgctgct ggagcgcggg gtctacgtga tcggcttctc
    15541 gtaccccgtc gtaccgatgg gccaggcgcg catccgggtc cagctgtcgg cggcgcattc
    15601 gaccgaggac gtccggcggg cggtggcggc gttcgtcgac gcgcgcgacg cactcaaggg
    15661 ctgagaccgc cgggccgggg gagcgcgagg ccgaacggcg ccgggtccgg cacgcgccgg
    15721 gcccgaaacc gccgtggcct ggcaggatgg gcgcgtgatc gacccccggc gcctgcgcat
    15781 cctgcgagcc gtggcggacc accgcacggt gaccgccgcg gccgccgcgc tgtatctgac
    15841 cccgtccgcc gtctcccagc agctcgccgc actggagcag gagaccggcc acgcgctgct
    15901 gacccgcagc ggcaggggcg tacgcctgac ggcggccggg gagatcctgc tcacacacgc
    15961 ccacgaggtc ctcgcgcagc tggagcgggc cgaggcggag ctggcggcgt acgcgggcgg
    16021 ggcggccggt gaggtcaccg tcgccgcgtt cgccacgggg atcgccgagg tgctggcccc
    16081 ggccgtcgcg cacctcgccg actcggaccc gggcatccgc gtacgggtac gggactccga
    16141 gggcgacgag agcctgccgc tgctcctcga cggccaggcg gacgtggcgc tggccgtcga
    16201 gtaccggggc gcgcccaccg aggacgaccc ccgcctgtcg cgcgtgccgc tgtacgccga
    16261 gccgttcgac gcggttctgc ccgaggggca cccgctgcgc cacgagatcg aggtgccgct
    16321 cgccgggctt tcggacagcg actggatcag cccgtacccg ggcaacccct gccacgaagt
    16381 gatgcgcctc gcctgcgagt tggccggttt cgaaccacgc ctcgtgcact cctcggacga
    16441 cttccgcgcg gtggtcgccc tggccggcgc gggtgcgggg gtggcgctcg tgccgcgctc
    16501 ggcgctgcgc gggatggagc tgaagggcac ggtcgtacgc ccggtgtccg gcccgcccgc
    16561 cacccgccgg gtcttcgcgg cggtccgcag gggcgcggag caccacccgc tgatccgccc
    16621 ggtcctggac gcgctcacgg agtcggcgtc gggcctgacg acgggctgag caccccgccg
    16681 ccgaccgccg gacgcgcctg ccacccgtcc ggtcaccact cccccttccc ccatgtacgg
    16741 ggcccgctcc ttgtggggcg aacgaccgtc acactccgcg atcgagccgg attaccgtgc
    16801 tcgtcgtacg aggccgacac cggtcgtcgg ggcgcgtgac cgacaccggg cggggagtcg
    16861 ccatgaccag gcgcgccccc gctctcgccg ccctgaccgg cgcccgcgac gtggaggcgc
    16921 gtccggtccg gccgcgcggc cggaccggac gcgcctccgc tgtgcacgaa ccgcccctac
    16981 gacacaggag tcgccatgtt cagaagcgcg ctgcacacat cgctcgcact cgtcatgatc
    17041 tcggccggcg caatcgtcgg tgcgacggtc accgccggtc ccgcgcacgc cgcgtccgac
    17101 tgtggccagc cgatcaccgg cctgcccttg cagcagggca gccagggcac ctcggtggag
    17161 cgcctgcaga tccgtgtcgc cgggttcgtg gacagcggcg aagtgctctc ggccgacggg
    17221 gtctacggcg ggcgcaccaa agaggcggtc cgtaagttcc aggcgcagta cggccttcag
    17281 gccgacggga tcgccggcag ccggaccgtc gacaagatct acgcgctgca ggactcggac
    17341 tgcacgccca tccacttctc ctacgccgag tggaacaagt gcaactccac ctggtcgggc
    17401 ggcgcggttt cggcgtccgc cgccaaggcc aacgcgcgca ggagcatgtg gaagctggag
    17461 gcgctgcgcc agaagctcgg cggcaacccg atccagatct ccagcggatt ccgctcgaac
    17521 agctgcaacg aggccgtggg cggtgtcagc ggcagccggc acacctacgg ggacgccgcg
    17581 gacatgccgg gcacacagac ctggcgctgc aagctccaca acggcgccaa gagctccggc
    17641 ttcagggaga ttctcggcca gggcttcacg ggacacaacg accacaccca tgtgggcatg
    17701 accggctcac gtcagtggca cggttgctga gagaggcgac gacccgatcg tgtccatgag
    17761 cagacgaagc ttcctcggcg ccggcgcgtt caccgtgctc ggcgccggtg cggccgggtg
    17821 cgactcgggc gccggcggcg acaccacggc caccgagcct ctcctcgccc tcgttcccga
    17881 ggacggcacc acgcggatcc acgcggcgac ggtcagccgc ttcaacaagt cgccggccaa
    17941 ggcgcgagca gaggcgaccg ccgagctgcg cgacgccccg gcgtcgtcgt acgaccgcgt
    18001 gcttgacagg gcactggacg gcgaccgcgg cccggacctc ctcttcacct ggagcgcggg
    18061 agccatccgc gtctcggccg aggagcaccg gctggtcgac ctctacaacc tcaccgagga
    18121 ctaccccgag ttcggcgaga ggctgctgcc cggtgtcctg gagggctgcg ccgtcaacca
    18181 ccgccccttc ggcatccccg tccgcggcac ccggcccgtc gtcctgttct accatcgcgc
    18241 cctgttcgcg gatctcggcc tccaaccgcc cgccacctgg tcggatctga agaaggccgg
    18301 agcccggctg cgcgccgcga acgtcgtacc cgtcgcgctg gccggatccg atcccgccgc
    18361 ggcggcgagg tggctggagt acctggtgga gcgcatcggc ggccccgggg tcgcggaccg
    18421 tgtccggtcc ggggaccacg gcgcgtggag cgaccggacc gtgctgcggg cggcgcagga
    18481 ggtcatctcc ctgctcgaca gcggttcgtt cggcgacggc gtcggcggcg gcgaggccgc
    18541 caccgacagc gaggccgccg cccttctcgc cgggggccgg gccgggctgc tcctcgcgga
    18601 gtccgcgcag cacgcggagc tcgcccggaa gttccccgtg ttcaccgaca agcacctggg
    18661 gtgggtgccg ttcccgacgg tcgagcgggg cagggggaag ccggagagtc tgctgggcac
    18721 cccggccggt tatctgacgg tgagcgagcg caccgagaac cggctggccg ccgtcgccct
    18781 gctgaaggag ttcaccggta cggaacacag cgaggctctg ctgcgggccg gcgacgtccc
    18841 cgccacgacc accgcggcga agctgctcga ccacgcgccg aatccggagt tcacacgatt
    18901 ccagtacgaa ctggtacgga aggccccgaa ctacaccgtc agctgggaga gagccgtaca
    18961 cccggcgtgg cgcgatccca tgctcaccga ggtgggcgac ctgttcgccg ggcggtccac
    19021 ggcacgggag ttcagcgagg cgatgcggcg cgtggaactg cccgtggcgc ggtgagcgcg
    19081 gccggtggga cgttcggaac cgacaggact caggcgacca gccgcacgat caggaccacc
    19141 acgatcacga tgaccgcccc cgccgcgatc agtcggcgtt tcagccggtt cgagagggtc
    19201 gcgacgacct ccaggctccg gtcgcccggg aagacgtgga agacccggtt cggatcgccg
    19261 gtcagctcca cccgggccag cgggcaggtt tcgagggtca cccgccggga cagctccgcg
    19321 ttccggtggg ccaggtggtt ggccacggcg gcccggtgcg tgccgtggac accggagggc
    19381 accgcgccgt cggcggggac ttcctggcgc cgccagcggg cggcggccag ccgctcgcgg
    19441 accttgtcgg gccagtcggg cgcgggcagc gacaaggagg ccttctcgtg cgtgtacgcg
    19501 acggtgccct ccacccagtg ggtgaggctg cccttgccgc cgcacacgtc gtgcgggccg
    19561 acgccccgcc ccgagcagcg cgcgcacgtc tcccggcccc ggccctcgca gtgcgggcac
    19621 cggacccggc cccgccccga gcagccgcga caggcggcct cggaggtacc gcacagcgcg
    19681 caggtgatcc gcggggcgcc gggcgccgtg gcgcgcggac cggtcgcggc ggggcgcgcc
    19741 ttcaccgtac gcgtccggcg tccgccgctc ttctcgcact ccgtgcaggg ggcgacgtcc
    19801 aggcacagac cgcacgcggg cggctcgttg cggcaggtgc agtcgtgccg gccgctgccg
    19861 cagcaactgg cgcaccgcat cgtgccgttg tcgcacgggc agggcacgag ccggtgggag
    19921 tgcgcacgga gcagggtgac cctgcccggc tcctcgggcg gcgtcagccg gtggtccgcg
    19981 atggcaccct cgtaaagagg aagcgccgac agatccttcg taccgaaggc ggtccgctgt
    20041 gtctcgccgc gccgctcggt gaagcggacg acctcgcagc gcaccaactg cctgcgcgtg
    20101 acgtcccgga gccggcccgc gtcggccacc gttccgccgc ccctggtcgc gtacggggcg
    20161 agcgccttga gaaggtccgc gtcgggcagc gcggcgtaca gggcgtcgtc gttcggtgcg
    20221 tcggacatgg gcgtgtctcg tccctcctcc ggcgcgcggc gacgccgcgc ggatcgcagg
    20281 ttaggactgt tgccgaccca ccatcaagag ggcggtgcga gacacgggcc ggcggggcgg
    20341 atgggtgccc ggcacttccg tacgccggtt tcccacccgc cccgcgggcc ccgtgagcgc
    20401 cctacgacag caggttcggt gccgcccggt ccagcaccga accgacgcgt tcccaggtct
    20461 ccatgtcccg tgtcaccgag gggagttcgg ggccgtcgcc ggtcttccag gtggtggcga
    20521 tcgcgaccgg gtcctcgccg ctggcggccg acgccgccag cgccgccgcg cccagggcga
    20581 ccagctcgcc gctctccggc acgatcaccg gccgcccgga gaggcgccgt acggtctcca
    20641 cccacgtacg gccctgggcg ccgccgccca ccagacgcag cggccggttc gccgcctcgg
    20701 ggtccgccgg gtcgaggccg caggcgcgca ggacctcgtc cagcgcccgc aggaccgtgt
    20761 acgccgcgcc ctcgtaggcc gcgccgagca actgctgcgg cgtcgtgtcg tgccgcaggc
    20821 ccgtcagcag gccggcggag gtcggcagat cgggggtgcg ttcgccgtcg aggtacggca
    20881 gcagcaccgc ctcgccgccg ggcgccacgt cctcgcggtc cagccgcagc agttcggcga
    20941 ccttgtcgac ggcgagcgtg cagttcaggg tgcagccgag cggcaggaac gtgccgtcgg
    21001 ccgccgcgaa cccggacagc gcggccgagg ccggcctggt gcgggtggcg gcgaagacgg
    21061 tgcccgacgt gccgaggctc agt
//
