LOCUS       NZ_CP048397            21239 bp    DNA     linear   CON 08-MAY-2024
DEFINITION  Streptomyces sp. S4.7 chromosome, complete genome.
ACCESSION   NZ_CP048397
VERSION     NZ_CP048397.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. S4.7
  ORGANISM  Streptomyces sp. S4.7
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7920066)
  AUTHORS   Bekiesch,P., Zehl,M., Domingo-Contreras,E., Martin,J.,
            Perez-Victoria,I., Reyes,F., Kaplan,A., Ruckert,C., Busche,T.,
            Kalinowski,J. and Zotchev,S.
  TITLE     Viennamycins: new lipopeptides produced by Streptomyces sp. S4.7
            isolated from the rhizosphere of Edelweiss (Leontopodium nivale
            subsp. alpinum)
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7920066)
  AUTHORS   Bekiesch,P., Zehl,M., Domingo-Contreras,E., Martin,J.,
            Perez-Victoria,I., Reyes,F., Kaplan,A., Ruckert,C., Busche,T.,
            Kalinowski,J. and Zotchev,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-FEB-2020) CeBiTec, Uni Bielefeld, Sequenz 1, Bielefeld
            33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8; canu v. 1.6
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 57.8x
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_010384365.1-RS_2024_05_06
            Annotation Date                   :: 05/06/2024 10:27:30
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,027
            CDSs (total)                      :: 6,939
            Genes (coding)                    :: 6,650
            CDSs (with protein)               :: 6,650
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 289
            CDSs (without protein)            :: 289
            Pseudo Genes (ambiguous residues) :: 0 of 289
            Pseudo Genes (frameshifted)       :: 103 of 289
            Pseudo Genes (incomplete)         :: 223 of 289
            Pseudo Genes (internal stop)      :: 23 of 289
            Pseudo Genes (multiple problems)  :: 52 of 289
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:05:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5907972
            Orig. end                         :: 5929211
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP048397.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Zotchev Lab, University of
            Vienna, Austria.
            Annotated using prokka v1.11 from http://www.vicbioinformatics.com.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21239
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="17"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21239
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21239
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11239](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11239
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(483..1442)
                     /locus_tag="SSPS47_RS26330"
                     /old_locus_tag="SSPS47_26635"
     CDS             complement(483..1442)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144156.1"
                     /locus_tag="SSPS47_RS26330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_26635"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_164253125.1"
                     /transl_table=11
                     /translation="MPHTQPTRHAQQTQHTQQTQEITLGDVTITRVEETHGPIMPADQF
                     FPDLPEQAWKDHRETLVPDHLGAEDTMVHAAMQTWVLRSEGRIILVDTGVGNDKSRPAV
                     ASWDRLSLDYLGNLARAGVRPEDVDLVINTHLHVDHVGWNTRLSDGTWIPTFPNADYLM
                     PRADLEFWNPANNPNITGGVNENVFEDSVAPVHAAGLTLLWEGSHRIDANLRLDAAPGH
                     TPGSSVITLTSGADRAVFAGDLLHTPLQIMEPEHNSCFCEDPVGSRVTRRRILGWAADN
                     NALLIPAHLSGHGAAEVRREGRKFAIEGWAPFTPYTHA"
     misc_feature    complement(1474..1487)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.86"
                     /tool="antismash"
     gene            complement(1512..2573)
                     /locus_tag="SSPS47_RS26335"
                     /old_locus_tag="SSPS47_26640"
     CDS             complement(1512..2573)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015034169.1"
                     /locus_tag="SSPS47_RS26335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_26640"
                     /product="hypothetical protein"
                     /protein_id="WP_239065051.1"
                     /transl_table=11
                     /translation="MPENSEGIMLKKLSTAAVTTAVTLTVSVAGLAPATATSTTSETGT
                     SARAAQSAGAASAGTTSATGTVDNARTVAHFDLAKGQLPENVALSPGGTAYVTFAAARQ
                     IARVTPSGTTRILATLPEPADGGIHTPVLGFALTTGIVRAHDGTLYVLYATGTDVLTGL
                     WRLRPGGEPRRIAPLPAGGLPNGLALDPRTRTLYITDSVLGVIWTVPTTGGTPSAWSTG
                     PELASTGSLGANGLKIHRGAVWATNLDKGTLLRIPVLPGGRAGRVQTRATGLAGIDDFD
                     FTGRGDHVLATLNGPSEVALVRRDGTHSTVLTAADGLRSPTSVALRGDRVYVLSAAYTT
                     AEDPNLVLAHLKD"
     gene            complement(2673..3608)
                     /locus_tag="SSPS47_RS26340"
                     /old_locus_tag="SSPS47_26645"
     CDS             complement(2673..3608)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016640005.1"
                     /locus_tag="SSPS47_RS26340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_26645"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_164253126.1"
                     /transl_table=11
                     /translation="MNGKSRLGEFLRTRRSQLSPDEAEVPTYGERRRVPGLRREELALL
                     AGVSASYYARLEQGHSMNASPEVLDAIARALRLDESERLHLLDLARSAKPRGRGRRPAP
                     ERVTEATGQLLDALADVPAIVVGRRSDVLAWNRLGHALFAGHLDPGAPDLPDQRPNMAR
                     LVFLDAHTRELYTHWPSKARAVVGNLRMVAGQYPEDSALHALVGELSAKSEDFASLWAD
                     HRVKACTVADYEMRHPLVGALTVTQQTLNVGPGPTVVVATTRAGSPSRTTLALLAEVAT
                     EAGATAATAAPATAAAPAASSRPGNRVSDS"
     gene            complement(3795..4517)
                     /locus_tag="SSPS47_RS26345"
                     /old_locus_tag="SSPS47_26650"
     CDS             complement(3795..4517)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016473292.1"
                     /locus_tag="SSPS47_RS26345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_26650"
                     /product="cation transporter"
                     /protein_id="WP_164255025.1"
                     /transl_table=11
                     /translation="MAGEISLGPAPSRREALARRVRLLVGATIGYNVIEAIVALTAGSM
                     ASSSALVGFGLDSIVEVSSAAAVAWQFSAREHAVREAREKKALRVIAVSFFALATFVTA
                     DAVRALAGGGEAESSVPGIVLAALSLAIMPFLSAAQRRAGRELGSASAVADSKQTLLCT
                     YLSAVLLAGLVANAALGWSWADPVAALVIAAIAVKEGREAWRGDNCCAPAGPSSPKADG
                     NPPARSEDACGCAQGCAC"
     gene            complement(4517..4852)
                     /locus_tag="SSPS47_RS26350"
                     /old_locus_tag="SSPS47_26655"
     CDS             complement(4517..4852)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011029058.1"
                     /locus_tag="SSPS47_RS26350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_26655"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_164253127.1"
                     /transl_table=11
                     /translation="MLNLASEIEVLARFGRALADPIRCQLLLALRAAPAYPSDLADAIG
                     VSRTRLSNHLACLRDCGLVVAVPEGRRTRYELADPRLGHALDDLRTAVVAVAEDVTCAD
                     AEEKGCC"
     gene            5077..5445
                     /locus_tag="SSPS47_RS26355"
                     /old_locus_tag="SSPS47_26660"
     CDS             5077..5445
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998562.1"
                     /locus_tag="SSPS47_RS26355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_26660"
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="WP_147875249.1"
                     /transl_table=11
                     /translation="MRRLGDLEAEIMDCLWKWGRPATVREVVDDINTRRPAAYTTVMTV
                     ASILHGKGWLTRQKQGQAWLYTPVRSREAYSAALMEDALGASQDRPAALAHFVERMSDD
                     EVAALRQALRAVGRDVEP"
     gene            5442..5909
                     /locus_tag="SSPS47_RS36290"
     CDS             5442..5909
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SSPS47_RS36290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_343234905.1"
                     /transl_table=11
                     /translation="MNAAPALLGYAAAVGVLAPRVMLRSAWPHRAPVPAATVWFALALS
                     FSVCAALGALHLATPGAHLHGILYSCGAALGVGPPDAGAVRSLDVAVSVAVPAAQVAAF
                     TYHVLRARAARARHREISTGWAGRRRGWAPRCWSTRPRPPTACRAAVLGSW"
     gene            5846..6346
                     /locus_tag="SSPS47_RS36295"
     CDS             5846..6346
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013594.4"
                     /locus_tag="SSPS47_RS36295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="M56 family metallopeptidase"
                     /protein_id="WP_343234906.1"
                     /transl_table=11
                     /translation="MLEHAPPAAYCLPGRRFRIVVSSGAVELLSDAEIAAVVAHERVHI
                     AGRHHLLLAAARSFAVVFPGVPLARHAGQQIPLLLEMAADDGALHLHPQRTLATAMFEM
                     ASAGAVPKGALSAGGHTVHVRLRRILAPARRTHPAFRITVAGVAALLPLLPLLVACPPE
                     PAA"
     misc_feature    5895..5897
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            6556..7002
                     /locus_tag="SSPS47_RS26365"
                     /old_locus_tag="SSPS47_26675"
     CDS             6556..7002
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637105.1"
                     /locus_tag="SSPS47_RS26365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_26675"
                     /product="hypothetical protein"
                     /protein_id="WP_164253128.1"
                     /transl_table=11
                     /translation="MFGRKKKPNDLNDLMAQLRPDLSRESLGVGPDFPGVAPNPLLSSD
                     ARKRNAELRTGALALGVLVDWREVKGNPRVVLMFDVETAGGISFRGIADEDLTITELTR
                     LAPGQTLPVRCRPAVMDHCVALARDADPAHVQQLSDEIASRKRT"
     gene            complement(7064..>7667)
                     /locus_tag="SSPS47_RS26370"
                     /pseudo=""
     CDS             complement(7064..>7667)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019766672.1"
                     /locus_tag="SSPS47_RS26370"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="NlpC/P60 family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="LKQYLSQQRALQQQRARAGEQLTALQETRKELGSKKKEIQGKLAK
                     AQSLLNSLSAEERDERAAKEERVNRDSDRVDLGNEASASQRGAAAFAAAKSRVGMRTYG
                     EPPARTRSTAPD"
     gene            7663..7785
                     /locus_tag="SSPS47_RS36040"
     CDS             7663..7785
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SSPS47_RS36040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_275405173.1"
                     /transl_table=11
                     /translation="MSVAYDGNRYSFSAVPEGKYSFRDGDNKWRVAGYKYRTCG"
     gene            8056..8310
                     /locus_tag="SSPS47_RS26375"
     CDS             8056..8310
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SSPS47_RS26375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_164253129.1"
                     /transl_table=11
                     /translation="MAPSSTANTSTPPPPSTDDRPGHEGDDARRHSPFAASRPRAPGRR
                     SKGVLVPVNALLDAPTPTKTYGEVPGTTARKVHDKAQNS"
     gene            8489..9895
                     /locus_tag="SSPS47_RS26380"
                     /old_locus_tag="SSPS47_26690"
     CDS             8489..9895
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018535204.1"
                     /locus_tag="SSPS47_RS26380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_26690"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_164253130.1"
                     /transl_table=11
                     /translation="MTVEADRESVLARASGQQSLATAAARNLATIAKSVPQMQETSSRW
                     LMRMLPWVDVRGGTYRVNRRLSHTVGDGRVPFVQTGGRVAVVPAGLRELPALREYGDEA
                     VLDELAGRCEQVEFAPGAVLARAGDVRDRVFLLAHGRVDKVGTGPYGEDTGLDVLADGA
                     YFGDESLTVADAVWDCTFRATTACTVLVLSRRDVDNVAARDDSLRGHLGAALPRQRTNA
                     YGEAAIDLSAGHVGEPQVPHTYVDYELRPREYGLSIAQTVLKVHSRVADLFNDPMNQTE
                     QQLRLTLEALRERQEYELVNNKEFGLLSNCDHAQRLQPHDGAPTPDDMDELLSRRRGSK
                     FFLAHPRAIAAFGRECSRRGLLMEPVDVNGHHVPSWRGVPIYPCGKIPVSEARTTSIMC
                     MRTGEDDQGVIGLRQTGIPDEIEPSLSVRFTGIDEQAIISYLVTAHYSAAVLVPDALGI
                     LENVEVGRRH"
     gene            10001..11239
                     /locus_tag="SSPS47_RS26385"
                     /old_locus_tag="SSPS47_26695"
     CDS             10001..11239
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018835845.1"
                     /locus_tag="SSPS47_RS26385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_26695"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_239065052.1"
                     /sec_met_domain="T1TS (E-value: 4.6e-55, bitscore: 186.4,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRTSGADGPQSAWHGPPPARPPVLPTAQALPAPPPSPALERLLA
                     GPAGLGTAAARAFHPLGPSEEKDQPTDRDTAGRTDAGTGTDSGSDTSGDTAVRIPPLYC
                     PDALRDDPALGEEVNNRLVDWAEEIGIFTGRLERLRSHQFGRLFMLAHPDCDDPDRLMA
                     AARCGLAEWSVDDHWVDEGDDTEPELLGSRLAMTHAVVDPVRLPARYLAQFEEVVSQQP
                     VLRAFRSSLAHLSGIASTTQMARLRHELAVMFVGYGQEAEWRNSGRRPAVWEYLLHRYE
                     NAFYPCMVLIDPVGGYELPAREFADPTVRRTYLYAGMANVLLNDVYSMAKEDPGDTNLP
                     NLIATEDNCSLQEAVDRTAAIHDELMHTVEADCAVLAAAGSPQLRRYLAGLWAWMGGSK
                     QWHATSPRYRTAS"
     misc_feature    complement(11307..11321)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.16"
                     /tool="antismash"
     misc_feature    complement(11318..11331)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.43"
                     /tool="antismash"
     gene            11321..12178
                     /locus_tag="SSPS47_RS26390"
                     /old_locus_tag="SSPS47_26700"
     CDS             11321..12178
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016433228.1"
                     /locus_tag="SSPS47_RS26390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_26700"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_203557931.1"
                     /transl_table=11
                     /translation="MTIQNTTAHPLRSLYQKSVANYWNQERNPVNLRLGEVDGIYHHHY
                     GIGDVDRSALDGPEETRQERLTAELHRLECAQADLLMSHLGDITPADRLMDSGSGRGGS
                     SFVAHSRFGCQVDGVSISETQVAFANGQAEERGVDDNVRFHLKNMLHTGFESDTFQAIW
                     NNESTMYVDLALLFPEYARLLKHGGRYVTITGCYNDAYGLPSRAVSEINAHYICSIHPR
                     SKYFKEMAANRLVPVSVVDLTAATIPYWELRAESPLATGIEQAFLDAYKDGSFQYLLIA
                     ADKV"
     gene            complement(12250..12765)
                     /locus_tag="SSPS47_RS26395"
                     /old_locus_tag="SSPS47_26705"
     CDS             complement(12250..12765)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020548019.1"
                     /locus_tag="SSPS47_RS26395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_26705"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_164253132.1"
                     /transl_table=11
                     /translation="MDPDNLDEPRVRRATASDWPALAGIDSLAATGDGARRDSIRRWCE
                     RGAVLMAQAPSAPHGPSSPLGYAVLEYTFFEQGFLTLLMAAPNARRRGVGTQLLRAAET
                     TCATPKLFTSTNASNHAMRRLLSHAGWQRTGILHGLDEGDPELFYLCPRTRPFNDLSQT
                     GTSTAFPA"
     gene            12925..13248
                     /locus_tag="SSPS47_RS26400"
                     /old_locus_tag="SSPS47_26710"
     CDS             12925..13248
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012377589.1"
                     /locus_tag="SSPS47_RS26400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_26710"
                     /product="hypothetical protein"
                     /protein_id="WP_239065053.1"
                     /transl_table=11
                     /translation="MGVELRAVSGGVGGGVGKAGVRVAVVGAVAGAALLPAGAAQANVV
                     GIGNAVFGNTCVQDGVGARSEGATVAGSGLGGGNQAGPPLSLPRNHCGTSGIVCTALFR
                     ASV"
     gene            complement(13360..13677)
                     /locus_tag="SSPS47_RS26405"
     CDS             complement(13360..13677)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SSPS47_RS26405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_164253133.1"
                     /transl_table=11
                     /translation="MAVTGFSYAGEAAVGQRERDLGVQGGQGGEDVAVDEVFGKGADAV
                     RGLGEGADLADDPVPDVTVVVDDRRLGPGVPGAEEVRVGVVEIQAGDVPAADPAAATPA
                     R"
     misc_feature    complement(13702..13715)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.9"
                     /tool="antismash"
     gene            13705..13950
                     /locus_tag="SSPS47_RS26410"
                     /old_locus_tag="SSPS47_26715"
     CDS             13705..13950
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SSPS47_RS26410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SSPS47_26715"
                     /product="hypothetical protein"
                     /protein_id="WP_164253134.1"
                     /transl_table=11
                     /translation="MIIHEELAGPALGGTTEAREGALTRLLRATGGPAPSVAAGIPPPR
                     TEGAVDDLAVGIGRELFTPAHERLLRHHSALLHDRA"
     gene            complement(14017..15780)
                     /locus_tag="SSPS47_RS26415"
                     /old_locus_tag="SSPS47_26720"
     CDS             complement(14017..15780)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044496.1"
                     /locus_tag="SSPS47_RS26415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_26720"
                     /product="protein kinase"
                     /protein_id="WP_239065054.1"
                     /sec_met_domain="Pkinase (E-value: 7.5e-42, bitscore:
                     142.1, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDELRPQDPARIGVWQILARLGAGGMGQVYLGRSPGGRLVAVKVI
                     HDEISDHPESLARFRREAATMETVRSPYTAQLIEASLDASPYWLATEYVPGPTLRGAVT
                     GSGPFPPESALRLFAALAEGLATVHVHGVTHRDLKPQNVILAPQGPQLIDFGIARGLEQ
                     TLLTQVGMAPGTPGYAAPEVLLRNEVGPAADVFALGATIAFAATGRPPYGGGEASAVSY
                     RTVHEDINLAGVRDDLAALIRCCVAKDPAERPGLAAVIAGCAVDSALAADAHYRSVARD
                     AEAVPKGVPEDAPEPGTAVEPEAEPTPGHGPEAEPAPARWGYDETTPHPSPDRQPPPAT
                     RPRRRKGWLAVCALGLVVPLGLWLFPREDDGKDTEAGSTTVATTSGPTAKNDTEKGTKT
                     DAKDDAKDDPAQGPPDHIVNDRVSQDRWALSDDPQQASQGIGFCDLGSTADSSPPTDMQ
                     SSVSHTTGSGTATAAFRRKNAGKGKRPAPYYVSVGIRPPHETDRATGRPLKSVGKGVGF
                     TTKPVDLYSKWSSGGTIKFQYPDDFQAHFGARTVDAIPVSDDPGDWTVVLYHVEGGPTK
                     YTSIVCNGFHA"
     gene            complement(16214..17146)
                     /locus_tag="SSPS47_RS26420"
                     /old_locus_tag="SSPS47_26725"
     CDS             complement(16214..17146)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (12-216). E-value: 3.3e-28.
                     Score: 90.6. Matches aSDomain:
                     nrpspksdomains_SSPS47_RS26420_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010273300.1"
                     /locus_tag="SSPS47_RS26420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_26725"
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_164253136.1"
                     /sec_met_domain="ADH_N (E-value: 1.2e-06, bitscore: 27.0,
                     seeds: 66, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRAVRYDRYGAVDVLYVADVARPAPAADEVVVEVVAAGLNPGEI
                     GVREGLAHAIWPATFPSGQGSDLAGEVVAVGSAVSTPTIGAQVIGFTNRRAAQADYVAV
                     PADQVTPKPAAVGWDVAGSLFVAGTTAYAAVRAVGAEPGETVALSAAAGGVGSLAVQLL
                     RRQGVRVLAVAGEANHEWLASLGAMPIGYGEGIEGVEEQLRAAAPEGVDAFIDTYGSGH
                     VELAMRLGVAPVRINTIIDFPAAKKFGTKSDGNMAAARADVLAELAALVAEGAISVAVS
                     ATYPVEQVREAYAELARPHSRGKIVLRMR"
     aSDomain        complement(16499..17110)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SSPS47_RS26420_PKS_ER.1"
                     /evalue="3.30E-28"
                     /label="SSPS47_RS26420_PKS_ER.1"
                     /locus_tag="SSPS47_RS26420"
                     /protein_end="216"
                     /protein_start="12"
                     /score="90.6"
                     /tool="antismash"
                     /translation="VDVLYVADVARPAPAADEVVVEVVAAGLNPGEIGVREGLAHAIWP
                     ATFPSGQGSDLAGEVVAVGSAVSTPTIGAQVIGFTNRRAAQADYVAVPADQVTPKPAAV
                     GWDVAGSLFVAGTTAYAAVRAVGAEPGETVALSAAAGGVGSLAVQLLRRQGVRVLAVAG
                     EANHEWLASLGAMPIGYGEGIEGVEEQLRAAAPEGVDAFID"
     CDS_motif       complement(16661..16720)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SSPS47_RS26420_0001"
                     /evalue="4.00E-03"
                     /label="PKSI-ER_m5"
                     /locus_tag="SSPS47_RS26420"
                     /protein_end="162"
                     /protein_start="142"
                     /score="10.0"
                     /tool="antismash"
                     /translation="GETVALSAAAGGVGSLAVQL"
     gene            complement(17202..18065)
                     /locus_tag="SSPS47_RS26425"
                     /old_locus_tag="SSPS47_26730"
     CDS             complement(17202..18065)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009082043.1"
                     /locus_tag="SSPS47_RS26425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_26730"
                     /product="oxidoreductase"
                     /protein_id="WP_164253137.1"
                     /transl_table=11
                     /translation="MTTTVSGGTLTPAEGLTISRMGYGAMQLAGPCVFGPPKDPGQAVA
                     VLREAVALGVTHIDTSDFYGPTVVNELIREALHPYPADLHIVTKVGGRRSADGGWFSSL
                     EPADLKVQVQENLLHLGLDVLDVVNLRMDAEGASTDSLAEPFGALAELREQGLIRHLGL
                     SGVSDAQLTEAESIAPVVTVQNLYNLANRSDDALVDRCAAENIAFAAFFPLGGFSPLQS
                     ETLTSVAARLNASPQQVALAWLLRRSATTVLIPGTSSVGHLRENIAAAELRLPADAVAE
                     LDAIAG"
     gene            complement(18215..18739)
                     /locus_tag="SSPS47_RS26430"
     CDS             complement(18215..18739)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018488489.1"
                     /locus_tag="SSPS47_RS26430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="discoidin domain-containing protein"
                     /protein_id="WP_239065055.1"
                     /transl_table=11
                     /translation="MLILLAVGIWFALPHLAGLFGVAKEETGKPESVPPAECRASGAAK
                     GHPAGAAVDGFNNRYWAPKETGDGIGEFLECDFAQPVRLTKLIVFSGTSARKDEFLTQA
                     RPAGITVLLTSRDGELTTRTVRLRDQAGEQTFDLRGSETVRARFTVNSAYGTGEGRRIA
                     VAEVEFFGRRP"
     gene            complement(19312..19920)
                     /locus_tag="SSPS47_RS26435"
                     /old_locus_tag="SSPS47_26740"
     CDS             complement(19312..19920)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018099783.1"
                     /locus_tag="SSPS47_RS26435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_26740"
                     /product="phage tail protein"
                     /protein_id="WP_164253139.1"
                     /transl_table=11
                     /translation="MRAAVPGLPTPHPLIDQLPAVYLEQDFLRRFLDALDEVLAPLLLT
                     IDNVPAYLDHRTAPDDFLDWLAGWVAVEPHEDSPTDHRRTAVRGAVARHARRGTLGGLA
                     EAVRLETGTEPEIAESGGTAWSTSPNTPLPGRPVPWVTIRVRAAEGRPLDRVRLEELID
                     TEVPAHVGFSLELLPPDRDGDGNRNGNGDGDTGVGGAEG"
ORIGIN
        1 ggcgaagccc gtaccgtcgt acagcgccga acgcgtcgag cccgcgacga agccgccacc
       61 gtgcacgaaa accatcaccg gcaggccgcc gcccgcctcc tccggtgtcc agaggctcac
      121 cgtgaggaag tcctccccac ggctccaacc ggccccgaag tagggggaca tgtccacacc
      181 gccgagtcgg cgtccggact gaggggcgtt cggccccggc acggtcgcgt ccctcacctc
      241 gtgccacgag tcgtgcggcc ggggcgcctc gaaccggccg gccccggtgg gaggagcggc
      301 gtacgggatg ttcaggaagg agaggactcc gtcccgacga cggccgcgga cagcgccctg
      361 cgccgtggtg gcgacgggat cggcccgacg gttcgcgggg gtggtggggt gatggggcac
      421 tgcctcggcc tctctgtcgt ggcggtccgt gagtgggggt tcgcgggtgt caggcgtgag
      481 tgtcaggcgt gggtgtacgg cgtgaacggg gcccagccct cgatggcgaa cttccgtccc
      541 tcgcgccgca cttcggccgc accgtggcca ctcaggtgcg cggggatcag cagcgcgttg
      601 ttgtcggccg cccagcccag aatcctgcgg cgggtcacgc gggagccgac ggggtcctcg
      661 cagaagcagc tgttgtgctc gggctccatg atctggagcg gggtgtgcag caggtcgccg
      721 gcgaacaccg cgcggtccgc ccctgaggtc agggtgatca cgctggaacc gggcgtgtgt
      781 ccgggcgccg cgtccagacg cagattggcg tcgatacggt ggctgccttc ccacaacagg
      841 gtcagacccg cggcgtggac gggggcgacg ctgtcctcga agacgttctc gttgacacca
      901 ccggtgatgt tcggattgtt cgccgggttc cagaactcga ggtcggcccg gggcatcagg
      961 tagtcggcgt tggggaacgt gggtatccat gtgccgtcgc tcagccgggt gttccagccg
     1021 acgtggtcga cgtgcagatg ggtgttgatc acgaggtcga catcctcggg ccgtacaccg
     1081 gcacgggcga gattgccgag gtagtcgagg ctcagccggt cccaggaggc cacggcgggg
     1141 cgggacttgt cgttgccgac gccggtgtcg acgaggatga tcctgccctc gctgcgcagc
     1201 acccaggtct gcatcgcggc gtggaccatg gtgtcctcgg cgcccagatg gtcgggaacg
     1261 agtgtctcgc ggtggtcctt ccacgcctgc tcgggcaggt ccgggaagaa ttggtccgcc
     1321 ggcatgatcg ggccgtgcgt ctcttcgacg cgggtgatgg tgacatcgcc caaggtgatc
     1381 tcttgagtct gctgagtgtg ctgcgtctgc tgcgcgtgcc gagtgggctg ggtgtgcggc
     1441 atggttgttc cgttccgggg ttgctgacgc ggacgtacgt atgtacggat ggacggtcgg
     1501 accgtgcggt ctcagtcctt cagatgggcg aggacgaggt tggggtcttc ggcagtggtg
     1561 taggcggcgc tcaggacgta gaccctgtcg ccgcgcagcg ccaccgaggt ggggctccgg
     1621 agcccgtcgg cggcggtcag gaccgtggag tgggtgccgt cgcgtcgtac gagcgccacc
     1681 tcgctcgggc cgttgagggt ggccaggaca tggtcgccgc ggccggtgaa gtcgaagtcg
     1741 tcgatgccgg ccaggccggt ggcccgggtc tgcacgcggc cggcgcgtcc gccggggagg
     1801 acggggatgc gcaggagggt gcccttgtcg aggttggtgg cccacaccgc gccccggtgg
     1861 atcttcaggc cgttggcgcc gagggatccg gtggaggcca gttcggggcc ggtggaccag
     1921 gcgctggggg tgccgcccgt ggtggggacg gtccagatga cgccgaggac ggagtccgtg
     1981 atgtagaggg tgcgggtacg ggggtcgagg gccaggccgt tggggaggcc gcctgcgggc
     2041 agcggcgcga tgcggcgcgg ttcgccgccg gggcgcaggc gccacagacc cgtgaggacg
     2101 tcggtgccgg tggcgtacag cacgtaaagc gtgccgtcgt gggcccggac gatgccggtg
     2161 gtcagggcga agcccaggac cggggtgtgg attccgccgt cggccggctc gggcagtgtg
     2221 gccaggatcc gggtggtgcc gctgggggtg acccgggcga tctgacgggc ggcggcgaag
     2281 gtgacgtacg cggtgccacc gggggacagc gcgacgttct ccggcaactg ccccttggcg
     2341 aggtcgaagt gcgcgacggt ccgggcgttg tccacggtgc ctgtcgcgga cgtggttcct
     2401 gcggacgcgg cccccgcgga ctgggccgct ctcgcggacg tgcctgtctc ggacgtggtg
     2461 gaagtggctg tcgcgggagc gaggccggcc accgacaccg tgagggtgac cgcggtggtg
     2521 acggcggccg tggagagctt cttcaacatg atgccttcgc tgttttcggg catgcggcag
     2581 cggtacgcag acgcgtgagg ggtgttgggc ggctcccgcc cgggagtggg cggggcgtgg
     2641 ccggggttgg gaccggtgct tcgggtagga ggtcagctgt cgctgacgcg gttccccggt
     2701 cgcgacgagg cggccggggc ggctgcggtg gccggggcgg ccgtggcggc cgtagcgccg
     2761 gcctcggtgg cgacctcggc gagcagggcc agggtcgtac gggaagggga gccggccctg
     2821 gtggtggcga ccacgacggt ggggcccggc ccgacgttca gggtctgctg ggtgacggtc
     2881 agcgctccga cgagcgggtg ccgcatctcg tagtcggcga cggtgcacgc cttgacgcgg
     2941 tggtcggccc acagcgaggc gaagtcctcg ctcttcgcgc tcagttcacc caccagcgcg
     3001 tgcagtgcgg agtcctccgg gtactgcccc gccaccatcc gcaggttccc caccaccgcc
     3061 ctggccttgc tcggccagtg cgtgtacagc tcgcgggtgt gggcatcgag gaacaccagc
     3121 cttgccatgt tggggcgttg gtccggcagg tccggggccc cggggtccag atgtccggcg
     3181 aacagcgcgt ggccgagccg gttccacgcc agtacgtccg agcgcctgcc gaccacgatc
     3241 gcgggaacgt cggccagcgc gtccagcagc tgaccggtcg cctccgtcac ccgctccggc
     3301 gcgggccgcc ggcccctgcc acggggcttg gcggaccggg ccaggtcgag cagatgcaga
     3361 cgctcggact cgtcgagccg cagagcccgc gcgatcgcgt ccagcacctc cggcgaggcg
     3421 ttcatcgaat gcccctgttc gagccgggcg tagtacgaag cactcacccc cgccagcagc
     3481 gccagttcct cccgccgcaa ccccggcacc cggcggcgct ccccgtaggt gggcacctcc
     3541 gcctcgtcgg ggctcagttg ggagcgccgt gtccggagaa actccccgag ccgcgatttt
     3601 ccgttcatgg gcccgagtat gtgccgcccc gaaaaccccc gcctctccct gccggggata
     3661 ggtacgggcg ggagtggctg cccccccggg accggcggac cgggagcggg agggccgacc
     3721 gtcgacaccg cctgccgggc gtcgcgaact cccgcctgtc gggtgtcgcg cactcccgcc
     3781 tcgctggcgg aggttcagca ggcgcacccc tgcgcgcagc cgcaggcgtc ctcggaccgc
     3841 gcaggtgggt tgccgtccgc cttcgggctg ctcggaccgg ccggtgcgca gcagttgtcg
     3901 ccgcgccacg cctcgcggcc ctccttgacc gcgatcgcgg ctatgacgag tgcggcgacg
     3961 gggtcggccc aggaccagcc gagggcggcg ttggccacca ggcccgccag gagtacggcc
     4021 gacagatagg tgcacagcag cgtctgcttc gagtccgcga ccgcggacgc cgaccccaac
     4081 tcccggccgg cccgcctctg cgcggcggac aggaacggca tgatcgccag cgacagcgcc
     4141 gccagcacga tgcccgggac ggacgactcc gcctcgccgc cgcccgccag tgcccggacc
     4201 gcgtccgccg tcacgaacgt cgcgagcgcg aagaacgaca ccgcgatgac ccgcagcgcc
     4261 ttcttctcgc gcgcttcgcg cacggcgtgc tcacgggccg agaactgcca ggccaccgcc
     4321 gccgccgagg agacctcgac gatggagtcc aggccgaatc ccaccagtgc ggaggacgat
     4381 gccatcgacc ccgccgtgag ggcgacgatc gcctcgatca cgttgtagcc gatggttgcc
     4441 ccgaccagca gccgtacgcg ccgggccagc gcctcacggc gcgaaggcgc cgggccgagc
     4501 gatatctccc cggccatcag cagcagccct tctcctcggc gtccgcgcac gtgacgtcct
     4561 cggcgacggc caccacggcc gtacgcaggt cgtcgagcgc gtgccccagg cgggggtccg
     4621 cgagttcgta ccgggtacgg cgcccctcgg gcaccgccac caccagcccg cagtcgcgca
     4681 ggcacgccag atggttcgac aggcgtgtcc gggagacgcc gatggcgtcg gccaggtcgg
     4741 acgggtacgc gggagccgcc cgcagggcga gcagcaactg gcaccggatc ggatcggcga
     4801 gggcgcggcc gaaccgggcc agcacctcga tttcggacgc gagattcagc acggtgacga
     4861 cggtacatgg aatcctgaat tcatgaaacc atggacaatg agtggacccg tgcgacggtc
     4921 tgggcctccg cgtccagggc gctccgacct tcctcgtgga cggggccggc cgcgagccat
     4981 cggtcgtgcc ggttgcgcac cggggcacgc ctacgatggt ccggcgggcc acggcgcgga
     5041 agacgggcgc ggcagacggc ggaaggaact gcggaagtgc ggcggttggg ggacctggag
     5101 gccgagatca tggactgtct gtggaagtgg ggaaggcccg ccaccgttcg tgaggtggtc
     5161 gacgacatca acacacgccg ccccgccgcc tacacgactg tcatgacggt ggcttcgatt
     5221 ctccacggca aggggtggct gaccaggcag aagcagggcc aggcatggct ctacaccccg
     5281 gtgcgcagcc gggaggcgta ctcggccgca ctgatggagg acgcgctggg agcgagccag
     5341 gaccgcccgg ccgccctggc gcacttcgtg gaacgcatgt cggacgacga agtggccgcg
     5401 ctgcgccagg cgttgcgggc cgtcggccgc gacgtcgaac cgtgaacgcg gctccggcgc
     5461 tgctcggata cgccgctgcc gtgggcgtac tcgcgccgcg cgtgatgctg cgttccgcgt
     5521 ggccgcaccg ggcgccggtg ccggccgcca ccgtgtggtt cgcgctcgcc ctctccttct
     5581 ccgtgtgtgc cgccctcggc gcactgcacc tcgcgacgcc cggcgctcat ctgcacggca
     5641 tcctctattc gtgcggcgcg gcactggggg tcgggccgcc cgacgccggc gcggtgcgga
     5701 gcctggacgt cgccgtctcg gtggccgtgc cggcggctca ggtggccgcc ttcacgtatc
     5761 acgtactgcg cgcccgcgcg gctcgtgccc ggcaccgcga gatctcgaca gggtgggccg
     5821 gccgtcggcg cggctgggcg ccacggtgct ggagcacgcg cccccggccg cctactgcct
     5881 gccgggccgc cgttttagga tcgtggtgag cagcggcgcc gtcgaactgc tctccgacgc
     5941 cgagatcgca gccgtcgtgg cgcacgaacg ggtccacatc gccggccgtc accatcttct
     6001 gctcgcggcg gcacggtcct tcgccgtcgt gttcccggga gtgccgctgg cccggcacgc
     6061 ggggcagcag attcccctgc tgctggagat ggcggccgac gacggcgccc tgcacctcca
     6121 tccccaacgg accctggcca ccgcgatgtt cgagatggcc tcggcgggcg cggtcccgaa
     6181 gggcgcgctc tcggctgggg ggcacacggt gcacgtacgg ctgcgccgga tactggcgcc
     6241 cgcacgccgt acgcacccgg cgttccggat cacggtggcc ggggttgccg cgctgttgcc
     6301 gctgctgccc ctgctggtcg cctgcccgcc ggaaccggcg gcttaggacg tgtctggcga
     6361 aggttgagcg ttctggctgg aactctggtc ccgtgtcgcg ttttcagctc tcgacaagtc
     6421 cgtccgcgac cgcagacggc gaccccatcg ggacggggcg atgcgacggt ggtcgggaat
     6481 ggccgcgccg tacaatcgcg gtgagggcga agcgccaggc cgagattccg gcaccggtgt
     6541 gagggagggg tccggatgtt cggtcggaag aagaagccca acgatctgaa cgatctgatg
     6601 gcgcagctca ggcccgacct gagtcgggaa tcgctcggcg tcgggcccga cttcccgggc
     6661 gtcgccccga acccgctcct gagcagtgat gcacgcaagc gcaatgcgga actgcgtacg
     6721 ggggcgcttg cgctcggcgt tctcgtcgac tggcgggagg tcaagggcaa tccacgcgtg
     6781 gtcctgatgt tcgacgtgga gaccgccggc ggcatctcgt tccgcggtat cgcagacgaa
     6841 gacctcacga tcaccgagct cacccgactc gccccaggac agacgttgcc cgtgcgctgc
     6901 cggccggccg tcatggacca ctgcgtcgcc cttgcccggg acgcggaccc cgcccacgtg
     6961 cagcagctct ctgacgagat cgcgagccgc aagcggacct gacccgaagc catcggccgg
     7021 atccctgggc cctgcccggc ggatcttcgc ggcccgacac accctagagg cgtacgcccc
     7081 acatgaacgg cgtgccgctg cgcgcgatcg actcgtagcg cacctgggcg ccgggcttcg
     7141 gggagtggag gatctggccg ttcccgggta gaagccgaca tggctcagat cgctgcgcat
     7201 gatgacgagg tcgcccggct tgagcgcgct ccgggagttg atccgggtgc cgacattcgc
     7261 ctgggcctgg gacgtacggg gtatggagac gccggcctgc tggaacgccc aggacgtcag
     7321 tccggagcag tcgaacgagt tcgggccggt ggctccccat acgtacgcat gccgacccgg
     7381 ctcttcgccg ccgcgaaggc cgccgcgccg cgctgtgacg cgctggcctc gttgccgagg
     7441 tcgacacggt cgctgtcgcg gttcacccgc tcctccttcg ccgcccgctc gtcacgctcc
     7501 tcggcgctca gcgagttgag gagcgactgg gccttcgcca gcttgccctg gatctccttc
     7561 ttcttgctcc ccagctcctt acgggtctcc tggagcgccg tcaactgctc gccggcccgc
     7621 gcccgctgct gctgaagcgc acgctgctgg gacaggtact gcttgagcgt cgcctacgac
     7681 ggcaacaggt acagcttctc ggccgtcccg gaaggcaagt actccttccg ggacggagac
     7741 aacaagtggc gggtcgcggg ctacaaatac cgcacctgcg gctgacgcct gtccgaccct
     7801 gcgcgcctga ccgactcggt gcgcgccgcc ccggtggcgg ctgacccgcc gatggtgtgc
     7861 caagtacggg ggagcggccc gggggtgaat cccccgggcc ggccgcgttg gtcacgcgga
     7921 ccgccgcgga cgcgcgggct cggcccgtac tcccgtcctc ggtgtggttc gaaggtcact
     7981 tcgttcgagt cctcggcacg ctcgaacgcg ccggtgaagc cccggttctg ccggccgccg
     8041 tcacccttgt cggtgatggc tccctcgtcg acggcgaaca cgtcgacacc gccaccaccg
     8101 tcgaccgacg accgccccgg ccacgagggc gacgacgccc ggcgtcattc gccgttcgca
     8161 gcgtcgcgac cccgcgcacc tgggagacgg agcaagggcg tcctggtccc ggtcaacgcc
     8221 ttgctggacg cgccgacccc gacaaagacg tacggcgagg tgccggggac cacggccagg
     8281 aaggtccacg acaaggccca gaacagctga ccgggcgttc gggccgtccc ggggcgttgc
     8341 cgctgtggac atttgtgcgg ggaaacgtca ctgctggccg ggtaccccac tcgccgtcag
     8401 cgcattcacg tcctttcgtg tgatgacagg tgaagtaggc acgagggagg gtgattcggc
     8461 gtacctacag gagggccgag gatcacctat gaccgttgaa gccgaccggg aatccgtact
     8521 ggcgcgggcg tccgggcagc agagtctggc gacggcagcc gcgcggaatc tggcgacgat
     8581 cgcgaagtcc gttccgcaga tgcaggagac ctcgtcgcgg tggctgatga ggatgctgcc
     8641 gtgggtggat gtgcggggtg gcacctaccg ggtgaaccgg cggttgagtc acacggtggg
     8701 cgacgggcgt gtgccgttcg tgcagaccgg cgggcgggtc gcggtcgtcc ccgccgggct
     8761 gcgggagctg cccgcgctca gggagtacgg cgacgaggcg gtgctggacg agctggccgg
     8821 ccgctgtgag caggtcgagt tcgcaccggg cgcggtgctg gcccgggccg gtgacgtgcg
     8881 ggaccgtgtc ttcctgctgg cgcacggccg cgtcgacaag gtcggcaccg ggccctacgg
     8941 cgaggacacc ggtctggacg tcctggccga cggcgcctac ttcggcgacg agtccctcac
     9001 cgtcgcggac gcggtctggg actgcacctt ccgagccacc accgcctgca cggtgctggt
     9061 gctctcccgc agggacgtcg acaacgtcgc cgcacgcgac gactccctgc gcggccatct
     9121 cggcgcggcg ctcccgaggc agcgcaccaa cgcgtacggc gaggccgcga tcgacctctc
     9181 ggccggacat gtgggtgagc cacaggtccc gcacacctac gtggactacg agctgaggcc
     9241 gcgcgagtac gggctctcca tcgcgcagac ggtcctgaag gtccacagcc gtgtcgcgga
     9301 cctcttcaac gatccgatga accagaccga gcagcaactc cggctcaccc ttgaggcgtt
     9361 gcgcgagcgc caggagtacg aactcgtcaa caacaaggag ttcgggctgc tcagcaactg
     9421 cgaccacgcg cagcgcctcc agccccacga cggggctccc acccccgacg acatggacga
     9481 actcctctcg cgtcggcgcg gcagcaagtt cttcctcgcc cacccgcgtg ccatcgccgc
     9541 gttcggccgt gagtgcagca gacgcggcct gctcatggag ccggtggacg tcaacggcca
     9601 tcacgtgccc tcctggcgcg gcgtgccgat ctatccgtgc gggaagatcc ccgtcagcga
     9661 ggcccgtacg acctcgatca tgtgtatgcg tacgggggag gacgaccagg gtgtgatcgg
     9721 gctgcggcag acgggcatcc cggacgagat cgagccgagc ctgtcggtgc ggttcaccgg
     9781 catcgacgag caggcgatca tctcctacct cgtcaccgcc cactactccg cggcggttct
     9841 cgttcccgac gctctcggca tcctggagaa cgtcgaagtc ggccgccggc actgacacct
     9901 gccccctgcg ccccatcctg ccccgcgtcg gcccggcccg cgaacccccg ggccgtcagc
     9961 gggcgcgtca acctgccccc gtccgaaagg ttcctcacgc atgacccgaa ccagcggggc
    10021 cgacggccct cagtcggcgt ggcatggacc accgcccgca cgtccaccgg tcctccccac
    10081 ggcccaggcc ctgccggctc cgcccccttc cccggcgctc gaaagactgc tggccggccc
    10141 cgccgggctg ggcacggccg cggcccgtgc ctttcacccc ctcggcccgt cggaggagaa
    10201 ggatcagccg accgaccggg acacggccgg acgcacggac gcgggtacgg gcaccgactc
    10261 gggtagcgac accagtggcg acacggcggt gcgcatcccg cccctgtact gccccgacgc
    10321 cctgcgggac gaccccgccc tcggggagga ggtcaacaac cgcctggtcg actgggccga
    10381 ggagatcggg atcttcaccg ggcgcctcga acgcctgcgc tcacaccagt tcgggcgcct
    10441 gttcatgctc gcccatcccg actgcgacga ccccgaccgc ctgatggccg ccgcccgctg
    10501 cggactcgct gagtggtccg tggacgacca ctgggtcgac gaaggcgacg acacggagcc
    10561 cgaactcctc ggttcccgcc tggcgatgac ccacgcggtg gtcgaccccg tccgcctccc
    10621 cgcccgctat ctcgcgcagt tcgaggaggt cgtgagtcaa caacccgtcc tgcgcgcctt
    10681 ccggtccagc ctcgcccatc tctccgggat cgccagcacc actcaaatgg cgcgcctgcg
    10741 acacgagttg gccgtcatgt tcgtcggata cggacaggaa gccgaatggc gcaacagcgg
    10801 tcgcaggccc gcggtgtggg agtacctgct gcaccgctac gagaacgcct tctacccctg
    10861 catggtgctg atcgacccgg tcggtggtta cgaactgccc gcccgggagt tcgccgatcc
    10921 caccgtgcgg cgcacctacc tctacgcggg catggcaaac gtcctgctca acgacgtcta
    10981 ttcgatggcc aaggaagatc ccggagacac caacctgccc aacctcatcg ccaccgagga
    11041 caactgctcg ctgcaagaag ccgtcgaccg cacggcggcc atccacgacg aactcatgca
    11101 caccgtcgag gcggactgcg ccgttctggc ggcggcaggc tccccccaac tgcgccggta
    11161 tctggcgggc ctgtgggcgt ggatgggcgg cagcaaacag tggcacgcga ccagcccccg
    11221 gtatcggaca gcttcgtgac ggcgcccgat gacccgtagc cgggcagacc cgcgaagccg
    11281 tgaacccgca ttcccttaac cccttatgaa agagatgtcc atgaccattc agaacaccac
    11341 cgcccacccc ctgcgcagcc tctaccagaa gtccgtggcc aattactgga accaggagcg
    11401 gaaccccgtc aacctccgcc tcggcgaggt cgacggcatc taccaccacc actacggcat
    11461 cggtgacgtg gaccggtccg ccctcgacgg ccccgaggag acccggcagg agcgcctcac
    11521 ggccgaactc caccgcctcg aatgcgcgca ggccgatctg ctgatgagcc acctcggcga
    11581 catcaccccg gccgaccgcc tcatggactc cggctcgggg cgcggcggca gcagtttcgt
    11641 cgcccacagc cgcttcggct gccaggtcga cggcgtttcc atctccgaga cccaggtcgc
    11701 cttcgccaac ggccaggccg aggaacgcgg cgtcgacgac aatgtccgct tccacctcaa
    11761 gaacatgctg cacaccggct tcgagagcga caccttccag gccatctgga acaacgagag
    11821 caccatgtac gtggacctgg ccctcctgtt ccccgagtac gccaggctcc tcaagcacgg
    11881 tggccgctac gtcaccatca ccggctgcta caacgacgcg tacggactgc cgtcccgcgc
    11941 cgtcagcgag atcaacgccc actacatctg cagcattcat ccgcgcagca agtacttcaa
    12001 ggagatggcc gccaaccgcc tcgtccccgt cagcgtcgtc gacctgaccg cggcgaccat
    12061 cccgtactgg gaactgcgcg ccgagtcccc cctggccacc ggtatcgagc aggccttcct
    12121 ggacgcctac aaggacggca gcttccagta tctgctgatc gcggcggaca aggtctgacc
    12181 gccggccaca ggtagccgga gagcgacagc catcgtcgca aggaggggta cgagcggcag
    12241 gggcgggctc tacgccggga atgccgtcga agtgcccgtc tgcgaaaggt cgttgaacgg
    12301 acgagtgcgc gggcagaggt agaagagttc ggggtctcct tcgtcgagac cgtggagaat
    12361 ccccgtccgt tgccagcccg cgtggctcag tagccggcgc atggcgtggt tcgaggcgtt
    12421 cgtcgaggtg aacagcttcg gggttgcgca cgtggtctcg gcggcccgga ggagttgggt
    12481 tcccacgcct cgccggcggg cgttcggcgc ggccatcagg agggtgagga agccctgctc
    12541 gaagaaggtg tactccagca ccgcgtagcc cagagggctc gacgggccgt gcggcgcgga
    12601 cggggcctgg gccatcagga ccgcgccgcg ttcgcaccag cgccggatgc tgtcccgccg
    12661 tgcgccgtcg cccgtcgccg cgagggagtc gatcccggcc agcgccggcc agtccgaggc
    12721 ggtcgcgcgt ctcacccggg gttcatcgag gttgtcggga tccatgcgac ccatcgtggc
    12781 agcgggtacg gagtgcgcac gagcgtgtcg gagccgtcgc cgcgcagttg accgggtgcg
    12841 gccggacgaa tcgagtccgg cacgctctgt ggcaggtgac cgggaccgtg tgtcccctgg
    12901 tgatgccggg acgaaggagg agcgatgggc gtggagttgc gggcggtgag cggcggcgtc
    12961 ggcggcggtg tgggcaaggc gggcgtgcgg gtcgccgtgg tgggtgcggt ggccggggcg
    13021 gcgctccttc cggcgggtgc cgcgcaggcg aacgtcgtcg ggatcgggaa cgcggtgttc
    13081 ggcaacacct gcgtccagga cggggtgggc gcgcggtccg agggcgccac ggtggccggc
    13141 agcggactcg ggggcggcaa ccaggccgga ccgccgctga gcctgccgcg caaccactgc
    13201 ggcaccagcg gcatcgtatg caccgccctg ttcagggcgt ccgtctgatc cgaaagtccg
    13261 aagggcggtg cgggcggcgg gagttcagca ggatggtggt gagcggaccg gccccggtgg
    13321 ccggggtcga ggcacaggcg gtcacggagc tgctggccct cagcgggcgg gcgttgccgc
    13381 tgctggatca gctgctggta cgtcaccggc ctggatctcc acaacgccga cgcggacctc
    13441 ctccgcacct ggcacacccg gtcccagccg ccgatcgtct accaccaccg tgacatccgg
    13501 gaccggatca tcagccagat ccgcgccctc tcccagcccg cggaccgcgt cggctccctt
    13561 cccgaacacc tcgtctaccg cgacatcctc gccaccctgc ccaccctgga cgccaagatc
    13621 acgctcgcgc tgaccgaccg cggcttcccc ggcatacgag aagcccgtca cggccactgg
    13681 ctgctccacc acccggcggt ctgcgtgatc atccacgagg aactcgcagg tcccgctctc
    13741 ggcggcacca ccgaggccag ggaaggggcc ctcacccggc tgctgcgcgc cacaggcggt
    13801 cccgccccct ccgtggcggc gggcatcccc ccgccccgta cggagggcgc tgtcgacgat
    13861 ctcgcggtgg gcatcgggcg tgagttgttc actcccgcac acgaacgact cctccgccac
    13921 cacagcgccc tgctgcacga tcgcgcatga caccacgcaa cgtgcacgga ggtgctgttc
    13981 gacatgagga caccggccgg cgcgtggacg tgagagctac gcgtggaagc cgttgcacac
    14041 gatggacgtg tacttcgtgg gtccgccctc gacgtggtaa agcaccacgg tccagtcgcc
    14101 cggatcgtca ctcaccggga tcgcgtcgac ggtccgcgcg ccgaagtggg cctggaagtc
    14161 gtcggggtac tggaacttga tcgtgccgcc cgaggaccac ttggagtaga gatcgacggg
    14221 tttggtggtg aagccgacac ccttccccac cgacttgagg ggacgcccgg tggcgcggtc
    14281 ggtctcgtgc ggaggacgta tcccgacgga gacgtagtac ggcgcggggc gctttccctt
    14341 tccggcgttc ttgcggcgga aggccgccgt ggcggtgccc gagccggtgg tgtgcgagac
    14401 ggaggactgc atgtccgtcg gcggtgagga gtcggcggta ctgcccaggt cgcagaagcc
    14461 gatgccctgg gacgcctgtt gcggatcgtc cgacagggcc caacggtcct gcgagacacg
    14521 gtcgttcacg atgtggtccg gtgggccctg cgccggatcg tccttcgcgt catccttcgc
    14581 gtcggtcttc gtacccttct ctgtgtcgtt cttggcggtc ggcccggatg tggtggcgac
    14641 ggtcgtgctg cccgcctcgg tgtccttgcc gtcgtcctcc cgggggaaca gccagagccc
    14701 caacggcacg acgagcccca gcgcgcacac cgcgagccag cccttgcgac gtctcggccg
    14761 ggtggcgggg ggcggctgac ggtccggcga ggggtgcggg gtggtctcgt cgtatcccca
    14821 gcgcgccggc gcgggctcgg cttcgggccc gtgaccggga gttggctccg cttcgggctc
    14881 aaccgcggtt ccgggctccg gcgcgtcctc gggtacgccc ttgggtacgg cttcggcgtc
    14941 gcgggccacc gaccggtagt gcgcgtccgc cgccagcgcg gagtccaccg cgcatcccgc
    15001 gatcacggcg gccaacccgg gccgttcagc ggggtccttg gcgacgcagc accggatcag
    15061 cgcggccagg tcgtcccgta cgcccgccag gttgatgtcc tcgtgaacgg tccggtagct
    15121 caccgccgag gcctctccgc caccgtaggg aggccgtccg gtcgcggcga aggcgatcgt
    15181 cgctcccaga gcgaagacgt ccgccgccgg gccgacctcg ttacggagga gaacctcggg
    15241 cgctgcgtac ccgggggttc ccggtgccat cccgacctgg gtgaggagcg tctgctcaag
    15301 tccccgggcg atgccgaagt cgatcagctg cggtccctgc ggcgcgagga tgacgttctg
    15361 cggtttcagg tcccggtgcg tgacgccgtg gacatggacc gtggccagcc cctcggcgag
    15421 cgcggcgaac agccgcagcg cgctctcggg cgggaacggg ccgctcccgg tgacggcgcc
    15481 gcgcagtgtg ggtcccggca cgtactcggt ggccagccag tacggggagg cgtcgagcga
    15541 cgcctcgatc aactgggcgg tgtagggact gcgtacggtc tccatggtcg cggcttcccg
    15601 ccggaaccgg gccagtgact ccggatggtc actgatctcg tcgtggatca ccttcaccgc
    15661 caccagccgg ccgcccggcg aacggccgag atacacctgt cccatgccgc ccgcgccgag
    15721 ccgggcgagt atctgccata cgcctattcg cgcgggatct tggggtcgca gctcatccac
    15781 ggcacgactt tgccacatcc gggcctccgg cggacggcga ggaatgtacc aggaacgtac
    15841 taacgccctt cgctggtgga ggtgttgggg cccgagcggg acggcgacgc cgggcacccg
    15901 gccgaacgtg ccgagtcggg tacggcgcgg gtgcgcgtgg tgagcgagcc gtgcgcgacc
    15961 gccggcggcg gcggcgcggc ggcggggagg tgcggtgcgt ctccgacgac cttcccggtc
    16021 gctacggccg cgcgacggcc cggcctcctg atcgcacgcc ccgcaccggc tgaccagatg
    16081 cgctggctgg agttgaccca ccggttggtg agggcggctg ataccggcag gagcgcgccg
    16141 gacctccgac cccgcgcggc gggcggcacc gacgcagggc ctgcgcggcg acaccagccg
    16201 ccccgccgcc cggtcagcgc atccgtagga cgatcttccc ccggctgtgc ggccgggcga
    16261 gctccgcgta cgcctcccgg acctgctcga cggggtacgt ggcgctgacg gcgacgctga
    16321 tcgcgccctc ggcgaccagc gccgcgagct cggccaggac gtccgcgcgg gccgcggcca
    16381 tgttcccgtc gctcttggtg ccgaacttct tcgcggcggg gaagtcgatg atcgtgttga
    16441 tgcgtacggg ggcgacgccc agcctcatgg cgagttcgac gtggccgctt ccgtaggtgt
    16501 cgatgaacgc gtccacgcct tcgggcgccg ccgcacgaag ctgctcctcg acaccctcga
    16561 tgccctcgcc gtacccgatc ggcatcgcgc cgagggaggc gagccactcg tgattggcct
    16621 cgcccgcgac agcgaggacc cgcacgccct gacggcggag gagctggacg gcgagggagc
    16681 ccaccccgcc cgcggcggcg ctgagcgcga ccgtctcgcc gggctcggcc ccgaccgccc
    16741 ggacggcggc gtacgcggtg gtgcccgcca cgaacaggga ccccgccacg tcccagccga
    16801 cagcggcggg cttgggcgtc acctggtccg cggggacggc gacgtaatcc gcctgcgccg
    16861 cgcgccggtt ggtgaacccg atcacctgcg cgccgatcgt gggtgtggac acggcgctgc
    16921 ccacggcgac gacctcgccc gcgaggtcac tgccctgacc ggagggaaaa gtggcaggcc
    16981 agatggcgtg cgcgagcccc tcgcgtaccc cgatctcgcc ggggttgagc cccgccgcca
    17041 ccacttcgac gacgacttcg tcggcggccg gggcgggtct ggctacgtcg gcgacgtaca
    17101 ggacgtcgac cgcgccgtac cggtcgtagc ggacggctct gggcatgcga gtactccttc
    17161 gggctggtcg ggacggccgg gcgggactct gcggaaacgg cctagccggc gatggcgtcg
    17221 agttcggcga ccgcgtcggc cggcaggcgc agctcggccg cggcgatgtt ctcccgcagg
    17281 tggccgacgg aagaggtgcc cgggatcagg acggtggtgg ccgagcgccg gagcagccag
    17341 gcgagcgcga cctgctgcgg tgaggcgttc aggcgcgcgg cgaccgacgt cagggtctcg
    17401 gactgcaacg ggctgaaacc gccgagggga aagaacgcgg cgaaggcgat gttctcggcc
    17461 gcgcagcggt ccaccagggc gtcgtccgac cggttggcga ggttgtatag gttctggacg
    17521 gtcacgacag gcgcgatgga ctccgcctcg gtcagctggg cgtcggagac gccgctgagg
    17581 ccgaggtggc ggatcaggcc ctgctcgcgc agctcggcca gcgcgccgaa cggctcggcg
    17641 agggagtcgg tggaggcacc ctcggcgtcc atgcggaggt tgaccacatc gaggacgtcc
    17701 aggcccaggt ggagcagatt ctcctggacc tggaccttca ggtcggcggg ctccagcgac
    17761 gagaaccagc cgccgtcggc gctgcggcgc ccgccgacct tggtgacgat gtgcaggtcg
    17821 gcggggtagg ggtgcagggc ttccctgatc agttcgttga cgacggtggg accgtagaag
    17881 tcgctggtgt cgatgtgcgt gaccccgagc gcgaccgcct cgcgcagtac ggcgacagcc
    17941 tgtccggggt ccttcggcgg tccgaagaca caggggcccg ccagttgcat ggctccgtaa
    18001 cccatccggc tgatcgtgag accctccgcc ggggtgaggg ttccgccgga aacggtggtg
    18061 gtcatgtcgc gccttccttc ttctctctcg cctgccggac agatcatcca gggcatacag
    18121 gatgacttgc ccatttctca gctttcctcc ccgcgtgatg atctcggctg taggccgatc
    18181 cggcgcgatt ccgcagccgc cgggcggcgg tccgtcacgg tcggcggccg aagaactcga
    18241 cctccgccac ggcgatccgg cggccctccc cggtgccgta cgccgagttg acggtgaacc
    18301 tggcccgtac ggtctccgag ccgcgcagat cgaaggtctg ctcacccgcc tggtcccgca
    18361 gccggaccgt acgggtggtc agctcgccgt cccgcgaggt cagcagcacg gtgatcccgg
    18421 ccgggcgggc ctgtgtgagg aactcgtcct tgcgtgcgga ggtccccgag aacacgatca
    18481 gcttcgtcag ccgcaccggc tgcgcgaagt cgcactccag gaactccccg ataccgtccc
    18541 cggtctcctt cggcgcccag taacggttgt tgaacccgtc gacggccgcg cccgccggat
    18601 ggcctttcgc ggcgccggag gcgcggcact cggcgggcgg taccgactcg ggcttccccg
    18661 tctcctcctt cgcgacgccg aacagccccg ccagatgggg gagcgcgaac cagatcccca
    18721 ccgccagcag gatcagcacg atcggcagac cgatccgggg cctctgccat ccgcgtcgtg
    18781 ggcgtgtccc cgccacgggg gactgccggg ggccgcgagt gaggagccgg cgccaccacg
    18841 gcgggcggat cgcggggggc ggacccgggt ccaggaggag tgcgcagcgg acgcagagcg
    18901 tgcggtcggg ggtgttctcc gtacggcagt gggggcagac gaccggagtc ccggcgccgg
    18961 cgggcggcgt cggcggctcc gcgacagcgg ggcgggtatc cgggtccgac cacgcgtcgg
    19021 ggccgggcgc ggcccggtcc gcgctctcgc cggggcgtct gggcgcgccg accgtggagg
    19081 gcgggggagc ggagtccgga ggtgtggtcg ggggcggggg tacggacggt cccccagccg
    19141 cagcggatgg ctccgccaca cgcggcgccg ggtcgggcgc ggccccggcc tccgccgccg
    19201 gagccggggg cgcagtcgaa gacccctcgt ccggctccca cgcgaggaac gcctcgcacg
    19261 acgcacagaa ctcccgcccc ggcgcgttcc ggtgcccgca cgtctcgcag atcacccctc
    19321 cgcacccccc acgccggtgt ccccgtcccc gtttccgttc ctgtttccgt ctccgtccct
    19381 gtccggcggc aggagttcca gcgagaaccc gacgtgtgcc gggacctccg tgtcgatcag
    19441 ctcctccagc cgcacccggt ccaggggtcg gccttcggcg gccctgaccc ggatcgtcac
    19501 ccaggggacg ggccgacccg gcagcggcgt gttcgggctc gtcgaccagg cggtgccgcc
    19561 gctctcggcg atctccggct ccgtgcccgt ctccagccgg accgcttcgg ccagtccgcc
    19621 cagcgttccg cgccgcgcgt gccgggccac ggccccgcgt acggcggtcc tgcgatggtc
    19681 cgtggggctg tcctcgtgcg gctcgaccgc gacccagccg gccagccagt cgaggaagtc
    19741 gtccggggcg gtgcggtggt ccagatacgc gggcacgttg tcgatcgtca gcaggagcgg
    19801 ggccaggact tcgtccagcg cgtcgaggaa gcgccgcagg aagtcctgtt ccaggtagac
    19861 ggcgggcagt tggtcgatca gggggtgcgg cgtcggcagg ccggggacgg cggcacgcat
    19921 cggatcaggc tcctctcacc cggagttggt gttcgtagct gaagaccagc gcgtgccggt
    19981 ccagcgggat cttcgtggtc gcgtcggtac gttcaccggt ctccggatcg gcgcggtaga
    20041 gccgtacgtc ctccaccagg tccacgcccg gcacccgttg cagcacggcg aacgcctcac
    20101 ccgactggac cggccgaccg aacggccacc cctgaccggc cgggccgccg gtgagcgggt
    20161 tgaagtaccc gtacagtgcg gacagcgccg tctcccgcac cctctcgacc acggctccgc
    20221 gctccgcctg caccgacgcg acgacggtga cgccctggta gaacggcggc ccgaccgcca
    20281 gccgggtacc gatgggccgc cgtgcgttca gatgctccga gatcagggcg agcgtctgcg
    20341 cgggcgggac gagttcgccg aactcgatcc ggccccgcac gtcgccgcgt ccggcgggca
    20401 cgatgagcag ccgcaccccg cccgcgtcgc tcccgctccc ctcactgccg cccgtgccgc
    20461 ctccacccgc cttgccttcg cccgcacttc ggccaccggc cgccgccgcg gcgccgtccc
    20521 cggtcctgtc gtccttcgcg tccgcccgga tgcagtgcac gcgcgccgcg tccggggcga
    20581 tctcgcgcgc cagcagttcg tagtcgtgcg ggacgaccgc ccggtgcagc gtccgcagcg
    20641 tcatcggccc gcgcacccgg gcgctgtcga cgctctcgcc gtcgaccccg ccgagcgcgg
    20701 gccgccggtt ctccacccgc gccacgtacg ggatcgcgcc ccgcaggacc cgcagcgtgg
    20761 accgcgcgac attgccgcgc agcccgccgc ccgtgcggta cgaccgcacg cggacggtgg
    20821 cgcccttcac cggcacccgg ccgtagtagc ggatgccgcc gtcccgttcc cgtaccgcgg
    20881 ggccgaactc cacccgcccg gagttcgcgt ccagcgtgac atgccggtcc tcgggcccgg
    20941 agtgtgcgaa gtcgtccacg cgggtccacc gttcggcgtc cgcccccgcc ccgggaccgg
    21001 tcacctcgac cacgaactca ccgggcacca cgggcggccg ggccagcccg aaggcctggc
    21061 ccggcactcc ctcggcctgc cccagcacct cgtcggtgac ggtctcggcg tgctcggccg
    21121 ggacggtcgc gccgaccgtg aacgcggtga ccccgcggac caccggcggt gccacgtacg
    21181 tcggctggcc cggctccgcc tcgatcagcc ggcagcgcag ccagcccccg gtccgccgc
//
