LOCUS       NZ_CP048397            21041 bp    DNA     linear   CON 08-MAY-2024
DEFINITION  Streptomyces sp. S4.7 chromosome, complete genome.
ACCESSION   NZ_CP048397
VERSION     NZ_CP048397.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. S4.7
  ORGANISM  Streptomyces sp. S4.7
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7920066)
  AUTHORS   Bekiesch,P., Zehl,M., Domingo-Contreras,E., Martin,J.,
            Perez-Victoria,I., Reyes,F., Kaplan,A., Ruckert,C., Busche,T.,
            Kalinowski,J. and Zotchev,S.
  TITLE     Viennamycins: new lipopeptides produced by Streptomyces sp. S4.7
            isolated from the rhizosphere of Edelweiss (Leontopodium nivale
            subsp. alpinum)
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7920066)
  AUTHORS   Bekiesch,P., Zehl,M., Domingo-Contreras,E., Martin,J.,
            Perez-Victoria,I., Reyes,F., Kaplan,A., Ruckert,C., Busche,T.,
            Kalinowski,J. and Zotchev,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-FEB-2020) CeBiTec, Uni Bielefeld, Sequenz 1, Bielefeld
            33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8; canu v. 1.6
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 57.8x
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_010384365.1-RS_2024_05_06
            Annotation Date                   :: 05/06/2024 10:27:30
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,027
            CDSs (total)                      :: 6,939
            Genes (coding)                    :: 6,650
            CDSs (with protein)               :: 6,650
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 289
            CDSs (without protein)            :: 289
            Pseudo Genes (ambiguous residues) :: 0 of 289
            Pseudo Genes (frameshifted)       :: 103 of 289
            Pseudo Genes (incomplete)         :: 223 of 289
            Pseudo Genes (internal stop)      :: 23 of 289
            Pseudo Genes (multiple problems)  :: 52 of 289
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:05:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5138659
            Orig. end                         :: 5159700
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP048397.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Zotchev Lab, University of
            Vienna, Austria.
            Annotated using prokka v1.11 from http://www.vicbioinformatics.com.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21041
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="13"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21041
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21041
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11041](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11041
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    533..548
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.43"
                     /tool="antismash"
     gene            complement(713..970)
                     /locus_tag="SSPS47_RS23080"
                     /old_locus_tag="SSPS47_23360"
     CDS             complement(713..970)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018563321.1"
                     /locus_tag="SSPS47_RS23080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_23360"
                     /product="WhiB family transcriptional regulator"
                     /protein_id="WP_004937597.1"
                     /transl_table=11
                     /translation="MDWRHNAVCREEDPELFFPIGNTGPALLQIEEAKAVCRRCPVMEQ
                     CLQWALESGQDSGVWGGLSEDERRAMKRRAARNRARNATA"
     misc_feature    1013..1028
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     misc_feature    complement(1014..1025)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
     misc_feature    1189..1198
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 15.86"
                     /tool="antismash"
     gene            complement(1288..2256)
                     /locus_tag="SSPS47_RS23085"
                     /old_locus_tag="SSPS47_23365"
     CDS             complement(1288..2256)
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127486.1"
                     /locus_tag="SSPS47_RS23085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_23365"
                     /product="diacylglycerol kinase family protein"
                     /protein_id="WP_164252707.1"
                     /transl_table=11
                     /translation="MRALLVVNPAATTTSARTRDVLIHALASEMKLEAVTTEYRGHARD
                     LGRRAADSEDIEMVVALGGDGTVNEVVNGLLHGGPDPDRLPRLAVVPGGSTNVFARALG
                     LPNDAVEATGAILDALSNRSERTVGLGLAAGTPGTDDESVPARWFTFCAGLGFDAGVVG
                     RVEQHRERGKRSTHALYVRQVVRQFIDEPHRRRGMITLERPGEKPVTDLVLSIVCNTAP
                     YSYLGNRPLYASPGASFDTALDVLGLSKLSTPAVARYATQLLNSTPDRGPHGRHAVSLH
                     DLTDFTLQSKVPLPFQMDGDHLGLRTSVTFTGVRRALRVIV"
     gene            2360..2788
                     /locus_tag="SSPS47_RS23090"
                     /old_locus_tag="SSPS47_23370"
     CDS             2360..2788
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657893.1"
                     /locus_tag="SSPS47_RS23090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_23370"
                     /product="hypothetical protein"
                     /protein_id="WP_203557902.1"
                     /transl_table=11
                     /translation="MSSSERNTTDPSPRPGRLTAAAACAGLEALALVVGGVYMLAMGLL
                     GRPDSPQQAEMGGITLIALAVIPLLAARGLLLRRAWSRGPALVTQIMALPVAWTLLRSS
                     GPLIPAGIALAVVAGTALVLLVNPTTTEALGIRGRDSA"
     gene            complement(3083..3967)
                     /locus_tag="SSPS47_RS23095"
                     /old_locus_tag="SSPS47_23375"
     CDS             complement(3083..3967)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010072101.1"
                     /locus_tag="SSPS47_RS23095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_23375"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_187280057.1"
                     /transl_table=11
                     /translation="MPSGIPEQQARPHPVDGLDGRTAGAEQAQAERAATMSEHRQHDPH
                     DRSGARAMFIELRKLPEDSPERALLRNQLVRMHLPLVEHLARRFRNRGEPLDDLTQVAT
                     IGLIKSVDRFDPERGVEFSTYATPTVVGEIKRHFRDKGWAVRVPRRLQELRLSLTTATA
                     ELSQQHGRSPTVHELAERLGISEEEVLEGLESANAYSTLSLDVPDTDDESPAVADTLGS
                     EDEALESVEYRESLKPLLEDLPPREKRILLLRFFGNMTQSQIAQEVGISQMHVSRLLAR
                     TLAQLREKLLVEE"
     gene            complement(4054..4467)
                     /locus_tag="SSPS47_RS23100"
                     /old_locus_tag="SSPS47_23380"
     CDS             complement(4054..4467)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966375.1"
                     /locus_tag="SSPS47_RS23100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_23380"
                     /product="anti-sigma regulatory factor"
                     /protein_id="WP_023538758.1"
                     /transl_table=11
                     /translation="MSQIAGEPGTQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDE
                     IEDLRIAVDEACAILLQQAVPGSVLSCVFRLIDDSLEVTVSAPTTDGRAPERDTFAWTV
                     LSALAGKVDATVADDRTVAISLYKQRGAGPGPA"
     gene            complement(4719..4979)
                     /locus_tag="SSPS47_RS23105"
     CDS             complement(4719..4979)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966374.1"
                     /locus_tag="SSPS47_RS23105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_147873919.1"
                     /transl_table=11
                     /translation="MSECQHVADLPRPEPEPLSGTCLECEASGSHHVQLRLCLVCGHVG
                     CCDSSPHRHASRHFRDTGHPVMRSFEPGETWRWCFPDGSIV"
     gene            5015..6613
                     /locus_tag="SSPS47_RS23110"
                     /old_locus_tag="SSPS47_23385"
     CDS             5015..6613
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521043.1"
                     /locus_tag="SSPS47_RS23110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_23385"
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_164252708.1"
                     /transl_table=11
                     /translation="MDPLQLIALVAGSAVIAAAGRRTPVPAPLLLVTAGLGAAYVPGVP
                     SYVLDPHIVLPLLLPPLLHTAAVESSYLDLRANVRAVGLLSVGYVLFATLVVGYLAYLF
                     IPEMSLTAALVLGAVIAPPDAVAATAIARKLGLPSRITTILQGESLVNDATAITAFKVA
                     LAAAVGEGASWAGGIGEFALASLGGIGMGLVLMVPLHWLRTHLREALLLNTLSLLIPFV
                     AYAAAEQVGASGVLAVVVVGLYLGHRSWQVDFATRLQEQAVWKMVSFLLESVVFALIGL
                     QLPYVLKGLGSYGGMEVAGYAVGVFVTVVVVRYIWVFPATFVPRLLSKRIREREPDTNW
                     KAPLVVGWAGMRGVVSLAIAFSIPLTTHDGDAFPTRNLVLFLTFTTVIATLVVQGLTLP
                     TLIRLLKLPGRDSYAETLAEAQAQSRASVAAEQRLDELLADERNALAEPLADRLRNVLE
                     RRRNSVWERLGTVNELTGESADRTYQRLSREMIGVERDVFVTLRDERRIDDEMLRTLLR
                     RLDLEEAVAYREETG"
     gene            complement(6592..7572)
                     /locus_tag="SSPS47_RS23115"
                     /old_locus_tag="SSPS47_23390"
     CDS             complement(6592..7572)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004937622.1"
                     /locus_tag="SSPS47_RS23115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_23390"
                     /product="pyridoxal-phosphate dependent enzyme"
                     /protein_id="WP_164252709.1"
                     /sec_met_domain="PALP (E-value: 1.4e-17, bitscore: 62.7,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPEALDLAALRPRLPSPLRTVEDERFTRRGVRLLLKRDDLIHTA
                     LPGNKWRKLEPNLRAASGGGHLALLTFGGAYSNHLRATAAAGRLLGFATVGVVRGDELA
                     TRPLNPSLAACAADGMRLRFLDRATYRRKTEPSVLREILETAANGLAVPRERVYVVPEG
                     GSNSLAARGCTALGRELRGAADVVGVACGTGGTLAGLAAGLAPGQRAVGFPVLKGGFLA
                     GEVRALQLAAFGGPRGDWSLDERFHGGGYARTTPAADDFADDFEDRHGLPVERLYVAKM
                     LHGLTTLAEEGAFPPGSTVAAVVTGRPPDPAEGDGGDCGQPVSSR"
     gene            complement(7616..8194)
                     /locus_tag="SSPS47_RS23120"
                     /old_locus_tag="SSPS47_23395"
     CDS             complement(7616..8194)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030135.1"
                     /locus_tag="SSPS47_RS23120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_23395"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_164254889.1"
                     /transl_table=11
                     /translation="MSASSFIRALKNEGLTVVEVGDWRTHNRNHVGPWGPVHGVMMHHT
                     VTKGTANTVRICRDGYAGLPGPLCHGVISKDGRVHLVGYGRANHAGSGDDDVLRAVIAE
                     KTLPPDNEANTDGNRHFYGFECENLGDGKDPWPAVQVEAMEAAAAAVCRVHNWNGPSVI
                     GHLEWQPGKIDPRGVSMGGLRRRIDERLK"
     gene            8474..9880
                     /locus_tag="SSPS47_RS23125"
                     /old_locus_tag="SSPS47_23400"
     CDS             8474..9880
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061505.1"
                     /locus_tag="SSPS47_RS23125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_23400"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_147873916.1"
                     /transl_table=11
                     /translation="MSVGDEVRTVEPPSQQSLGTAAARNLATTTKSAPQMQEITSRWLL
                     RMLPWVQVQGGTYRVNRRLSYSVGDGRVTFVQTGDRVEVIPAELGELPAFRDFEDEEVL
                     AELANRCEQQEFAPGQTVAAAGGPADRVYLLAHGKVEKVGEGPYGDETVLEVLADGAYF
                     GDQALVDEEATWQYTARAATACTVLVLSRQDVLNLAERAQSLRGHLDALASIPAQRTNK
                     YGEAAIELSAGHVGEAVVPHTFVDYEGAPREYELSVAQTVLKVHSRVADLYNQPMNQTE
                     QQLRLTVEALRERQEHELVNNREFGLLNNCDYGQRLQPHDGAPTPDDMDELLSRRRGSK
                     MFLAHPRAIAAFGRECNKRGLNPATVEVGGHHVPAWRGVPIFPCNKIPVSDARTTSIIC
                     MRTGESEQGVIGLQQSGIPDEIEPSMSVRFMGIDEQAIISYLVTAYYSAAILVPDALGV
                     LENVEVSRWR"
     misc_feature    9908..9922
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 24.03"
                     /tool="antismash"
     gene            10001..11041
                     /locus_tag="SSPS47_RS23130"
                     /old_locus_tag="SSPS47_23405"
     CDS             10001..11041
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018892050.1"
                     /locus_tag="SSPS47_RS23130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_23405"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_203557904.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.8e-59, bitscore:
                     198.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSTDAATDGHEAVALLERSRSVVQPELRAAVESLPPAVRRVARY
                     HFGWERADGSPVAGGAGKAIRPALVLAAAQALGGEPHRAVPAAVAVELAHNFTLLHDDV
                     IDEDPTRRHRPTAWTVFGTTDAIIAGDALQALAMRLLAEDRHPASSPAAVRLTDCVIEL
                     CAGQQADCALELRGPNDVSLDECLTMAMAKTGALLGTSCALGALYADSGDEEVAALDAF
                     GREAGLAFQLIDDLIGIWGDPDRTGKPAGADLVAHKKSLPVVAALVSGHPAAEELADLY
                     LRPMDEAAVARAASAVERAGGRDWAQEQAADRMSRAVQQLAGAVPDLTRAGDLLALAEY
                     VTRRTR"
     gene            11199..11777
                     /locus_tag="SSPS47_RS23135"
                     /old_locus_tag="SSPS47_23410"
     CDS             11199..11777
                     /GO_function="GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973718.1"
                     /locus_tag="SSPS47_RS23135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_23410"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_164252711.1"
                     /transl_table=11
                     /translation="MRKLSYFVAASIDGFIGDPSGEAAFFTRFVDEEFLDFLKSEYPET
                     LPTHGRRPLGLDHLENKQFDTVIQGRRSYDLALKDGVTSPYAHMRQLVASRTLASPDPA
                     VEIVSGDLDARIRELKREDGLGIYLCGGANLAAQLIEEVDELVVKAYPLILGSGMPMFG
                     TEFALTEFELESHRAFGNGVVVRTYGRKR"
     misc_feature    11215..11235
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.83"
                     /tool="antismash"
     gene            11868..12308
                     /locus_tag="SSPS47_RS23140"
                     /old_locus_tag="SSPS47_23415"
     CDS             11868..12308
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015036104.1"
                     /locus_tag="SSPS47_RS23140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_23415"
                     /product="DUF6304 family protein"
                     /protein_id="WP_164252712.1"
                     /transl_table=11
                     /translation="MTAESTESWAGWYRDRRGAEPIAISADGRQVRTHIRGVAYEGADF
                     SVLEPTEAGGVLSSCVLEWDIPMPVSAGGTVQQATLSCLLTLGERPAGTPSGRAELSLT
                     LRCGGAAYESGIVGGGFRDALDRIKRQLPDDTEFEGRILVNA"
     gene            complement(12530..13183)
                     /gene="snpA"
                     /locus_tag="SSPS47_RS23145"
                     /old_locus_tag="SSPS47_23420"
     CDS             complement(12530..13183)
                     /EC_number="3.4.24.77"
                     /codon_start=1
                     /gene="snpA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018845525.1"
                     /locus_tag="SSPS47_RS23145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_23420"
                     /product="snapalysin"
                     /protein_id="WP_147873912.1"
                     /transl_table=11
                     /translation="MRYPKTAVSAICGISLAFATALTAAPVAAAAPTSDAPTTSYAAYE
                     GSAADTAATKAFYQAVMKSVAEKRAANPGALAVTVVYDASGAPSFAGQIASSTQIWNSA
                     VSNVQLQQGSNADFTYEEGNDPRGSYASTDGHGRGYIFLDYAQNQQYDSLRVTAHETGH
                     VLGLPDNYTAPCSKLMSGGGPGPSCTNSQPDAAERSEVNSLWANGFTAALAKAS"
     gene            13386..14417
                     /locus_tag="SSPS47_RS23150"
                     /old_locus_tag="SSPS47_23425"
     CDS             13386..14417
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003953996.1"
                     /locus_tag="SSPS47_RS23150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_23425"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_164252713.1"
                     /transl_table=11
                     /translation="MELEVRHLRALCAIADAGSLHKAARQLGMSQPSLTTQLRRIENSL
                     GAELFSRERTGCRPTLLGHSVLSRARPLIAGMAVLVSEARAAADRSAGPRLRIGSTASR
                     ALAGWLRRLRERLPGTDISLQMDVSANALLREVAGGGLDVAFVHEVEGCQLRVPPGLDR
                     RVLVEREPQFISLARDHPAAGRPVVELADLASDRWMIDPTVDGEWDGLRRVLSDAGLNP
                     PVLHGDYLTASSLIAVGEAIAPCQPTSVPREDMVVRPLRDDPLGVRLLLFSRPGAYEGA
                     GIASSGTSPDADRAGDGDGDGPGGAEVYADLEAAYREAALQAGVYRQWLTRNKSPLLHA
                     PAA"
     gene            14502..14882
                     /locus_tag="SSPS47_RS23155"
                     /old_locus_tag="SSPS47_23430"
     CDS             14502..14882
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018890808.1"
                     /locus_tag="SSPS47_RS23155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_23430"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_164252714.1"
                     /transl_table=11
                     /translation="MSPPVPTGDELVRVLATLSNPHRLRVVAALAGGRNYVSRLARELD
                     ISRALLQVHLKKLEAAGLVTSRLELSEDGKAMKFYEVNAFAVVLTPQDIVTAVQTLSSQ
                     SSQSSRSSRSSQKDERDEKGAT"
     gene            14882..15154
                     /locus_tag="SSPS47_RS23160"
                     /old_locus_tag="SSPS47_23435"
     CDS             14882..15154
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SSPS47_RS23160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SSPS47_23435"
                     /product="hypothetical protein"
                     /protein_id="WP_147873909.1"
                     /transl_table=11
                     /translation="MDDEQAWQEVIGAIGLFAILLIVVTLTLWHFTVGRRAREVRADEN
                     EYRQLAAQAVEGQRRTEKQLADLGRQLTDLQSRTGSLERILKDVE"
     gene            15286..17562
                     /locus_tag="SSPS47_RS23165"
                     /old_locus_tag="SSPS47_23440"
     CDS             15286..17562
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035: MMPL domain-containing transport protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014180855.1"
                     /locus_tag="SSPS47_RS23165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_23440"
                     /product="MMPL family transporter"
                     /protein_id="WP_164252715.1"
                     /transl_table=11
                     /translation="MLRRIKSERAGLVESVAGWSARNRTAAIAAWLLLVVIAVMSGSLF
                     PGEEARATDPGEAGRGQRMVSAQDAGDSIRENVMIRAGAGAAPATRRAATKDLVAALRA
                     VPDAVRDVGSPLGAHGGRWVSGDGMADLVTFEIAGPDAEFGAHRQAADAAVEKVTRQHP
                     GARVDQAGDSSLASAVDDVIKSDMRRAETTSLPLTVVILLVVFGSLAAAGIPLLLSATA
                     VAAAFGLLDTLGRWVPFNSAASAIVLLIGMAVGIDYSLFHLRRIREERAAGHPVQEALR
                     IASRTSGHAVLVSGLTVMVCMTGLLFTGVDVFKGLTLGTVLVVALAVLGSVTALPALVA
                     ALGDRVDLGRIPWLGRRRTAAGRSRLWTAVAGHVVRRPLLTGGVAALLLAVMALPAFGM
                     HLQDATQIQSLPRGVSAAADAGARMQQVFPGVTTPARVVVSADGPEIRAAADRLHEQAA
                     RSDGALREPITMVPVGEVLVIRVPLAGAGTDPRSEQALEFLRERALPATVGAVEGVDRV
                     EVAVAGRTAMPYDFTRQVNARTPLVFAFVLVLAFVLLAVAFRSLALPLVSIALNLLSIG
                     AAYGVLVAVFQGGRLESLLDFNAYGGVVSWLPLFMFIILFGLSMDYHIFILSRIRERWT
                     GSPGGRDASHEAIVGGIAASAGVVTGAAAIMVGVFSVFTTLSSIEYKMLGTGMAVAILI
                     DATVVRGVLLPASLTLLGDRAWTMPGRWGRGGSGSSAGRHEYGASTERAWSRANPTASG
                     KIPRP"
     gene            complement(17484..18062)
                     /locus_tag="SSPS47_RS23170"
                     /old_locus_tag="SSPS47_23445"
     CDS             complement(17484..18062)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003982936.1"
                     /locus_tag="SSPS47_RS23170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_23445"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_239065323.1"
                     /transl_table=11
                     /translation="MTPGARRALDAASRLFYERGIHAVGVDLIAAEAGVTKKTLYDRFG
                     SKEQIVVEYLAGRDERWRAFLDERLAAAPPSPAEHVLAVFAASRDWVAENGSRGCSMVN
                     AHAEIDDPEHPAYAVITGQKAWMLELFTTLAREVTAPGEAIGSEAADRLARTLMLLHEG
                     ALVAHGLGIFPDAVGFARDQARSVLAPYS"
     gene            18234..19166
                     /locus_tag="SSPS47_RS23175"
                     /old_locus_tag="SSPS47_23450"
     CDS             18234..19166
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089165.1"
                     /locus_tag="SSPS47_RS23175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_23450"
                     /product="DMT family transporter"
                     /protein_id="WP_164252717.1"
                     /transl_table=11
                     /translation="MNLLLAVAFVLCWSSGFIGAKLGAGSADAVTVLMWRFLPLALVLG
                     AVAVTRARAAWRGLTARDVLRQCVIGALSQSGYLLTVYYAIQLGVSSGTTALIDGTQPL
                     VAGALAGPLLRSHVSGRQWLGLCLGVTGVLVVTSADAAAAQGVEPWAYGVPFLGMLSLV
                     AATFLESRSRTVVAPSVAMTIHCGTSAVVFTALAAAAGAAVPPAETSFWVAVGWLVVLA
                     TFGGYGLYWLVLRRSGVMRVNTLMFLMAPVTAVWGAIMFGEPFGPSTAAGLAVALLAVV
                     VVRGGAARTAPGGNSGDVPARRADNGTWV"
     gene            19235..19663
                     /locus_tag="SSPS47_RS23180"
                     /old_locus_tag="SSPS47_23455"
     CDS             19235..19663
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005478015.1"
                     /locus_tag="SSPS47_RS23180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_23455"
                     /product="RidA family protein"
                     /protein_id="WP_164252718.1"
                     /transl_table=11
                     /translation="MVRRRVVPALFPPPGYAHAAVVETDRRLAFLAGSVPLDKDGTLVG
                     PGDFAAQTEQVLANLETALRAVGSDLDRVVTTDVYVVSSDPADLSRVWDVVHASGLTTG
                     PHTSTLLGVGCLGYTGQLVEITAVAEVAEAEDLALPAG"
     gene            complement(19800..20672)
                     /locus_tag="SSPS47_RS23185"
                     /old_locus_tag="SSPS47_23460"
     CDS             complement(19800..20672)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007821000.1"
                     /locus_tag="SSPS47_RS23185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_23460"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_164252719.1"
                     /transl_table=11
                     /translation="MSMSTQFTRTAEPLTGPRVGELPWIEDAGQVAPRDARELSKVFFQ
                     QLQVLEEGTHEYQYARNTLIEMNLSLVRFAAQRFRNRDDQLEDIVQVGTIGLIKAIDRF
                     ELSREVEFTSFAVPYIVGEIKRFFRDTSWAVHVPRRLQELRIQLARAKDQLAVRLDREP
                     TVRELAEHLKLSEEEIIEGLIAANGYNSDSLDLPADSGTGAPGRSGASVADFVGACDPA
                     MELVEDFHSLAPLLSTLDERERQILELRYGQELTQSQIGERFGVSQMQISRILARTLAK
                     LRDGMLADG"
     misc_feature    complement(20666..20680)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.3"
                     /tool="antismash"
     misc_feature    21019..21034
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.59"
                     /tool="antismash"
ORIGIN
        1 gctttctcag aatctggacg aacgggtcga gttcgacgag atcgccgacc gggtgctcgc
       61 gatggtgtcg gagatctcac ccggcaagac ggtccgccgg acgggccggt tcgggattct
      121 ggacgcggag gtggcgacgc ccctgtccat ggtcctcacc gagatcctgc agaacgcgct
      181 ggagcacgcc ttcgcgacgg gggagcgcgg cacggtcgag gtgcacgccg tccgaagcgg
      241 cgggaccttg cccaaacgcc ccgccgacga aggccgttcg gatgcccggc tgctcatcac
      301 cgtccaggac gacgggcgcg gactgcccga gggcttcgac ccgcgacggg ccggcaatct
      361 gggtctgcag atcgtacgaa ccctggtgga aggggagttg ggcggcggtt tcgacatgct
      421 tccgggccag gaacggggca ctcgggtgat cctcgacatc ccggtcgagc cgcacaagta
      481 accggagccg gcccgtcctt cgggccgtcc gctccgcacc ggccgactct tcttcacagc
      541 attctcaccg tggcccgcac agcaacgagc cccggaccgt ggtgacggtc cggggctcgg
      601 cctcaagctc tatgacgttt gcgcatcggg gggtactgcg cgctgcggct cgggggcggg
      661 gttatacgta cacgctgtac gcgccgccgt gctcaaggtc tgtggcgggg gctcaggcgg
      721 tcgcgttacg cgcccggttg cgagcggcac gacgcttcat ggcgcggcgc tcgtcctcgc
      781 tgaggccacc ccagacaccc gagtcctggc cggactcgag cgcccactgc aggcactgct
      841 ccatgacggg gcagcgacgg cagacggcct tggcttcctc gatctgcagc agcgcaggac
      901 cggtgttgcc gatggggaag aagagctccg ggtcttcctc gcggcaaacg gcgttgtgac
      961 gccagtccat ggctgctacc tctcttggtg ttacgtgcgg aatgcttgtg aatgtgaacg
     1021 ctttcacgaa tcccccgaca agggaagggc cgactcccag atgaactggt gtggtcctgg
     1081 tttgaggagg gggttctggc gctcagcgga ggccggtgat gcgggccgtc ccgagcgcca
     1141 tgtagagatt cgcaaacctc ggctgcggat acaacccctt caggaaagtt ttttttgatt
     1201 cctcggtgtc gactcggtca cagccgtact tccatggggt ggatgccagc ctaaacgttc
     1261 gagtgaaagg actttcccca cttccactca cacaatcaca cgcagtgcac ggcgtacgcc
     1321 tgtgaacgtc acgctagttc gcagtcccag gtggtcgccg tccatctgga agggcagtgg
     1381 gaccttcgat tgcaaggtga agtcggtcag gtcgtgcagg gaaaccgcgt gcctgccgtg
     1441 cggaccccga tcgggggtcg aattgagcaa ctgcgtcgca taacgagcca ccgcgggagt
     1501 cgacagcttg ctcagtccga gcacgtccag agcggtgtcg aacgaggcgc ccggcgacgc
     1561 gtacagcgga cgattgccca ggtaggagta gggagccgtg ttgcagacta tggacagcac
     1621 gaggtccgtg accggcttct cgccggggcg ctcaagggtg atcatgccgc gccggcgatg
     1681 aggctcgtcg atgaactgcc ttaccacctg gcgcacatag agcgcgtgcg tcgatcgctt
     1741 accgcgctcc cggtgttgtt cgactcggcc gaccactccg gcgtcgaatc ccagacccgc
     1801 gcagaaagtg aaccagcgtg cgggaaccga ttcgtcgtcc gtacccggag taccggccgc
     1861 cagtcccaga ccgacagtgc gttcgctccg gttactcagc gcgtccagaa tggcgccggt
     1921 cgcctccacg gcgtcattcg gcagcccgag cgcacgcgcg aagacattcg tcgaaccgcc
     1981 cggcacgaca gccagccgtg gcagccggtc ggggtccgga ccgccgtgca gaaggccgtt
     2041 gacgacctcg ttgaccgtgc cgtcaccgcc gagtgcgacg accatctcga tgtcctcgga
     2101 gtccgccgcg cgccgtccca gatcccgggc gtgcccccgg tactcggtcg tcaccgcctc
     2161 cagcttcatc tcgctggcca gcgcgtggat gagtacgtcg cgtgtgcggg cactggtggt
     2221 ggttgctgcc ggattgacca caaggagtgc gcgcatacgg aggagattac cggccacgga
     2281 cgcctgcccc ctccccgggc gggccgtgcc ccctccgggg gcccgccggt caccggggac
     2341 cggccgctac cctgctgggg tgagcagcag tgagcggaac accaccgacc cgagcccgcg
     2401 cccagggcga ctgaccgcgg cggcggcctg cgcgggcctc gaagccctcg cgctcgtcgt
     2461 cggtggcgtg tacatgctcg cgatgggtct cctcgggcgg cccgacagcc cgcagcaggc
     2521 cgagatgggc ggcatcaccc tcatcgccct cgccgtcatc ccgctgctcg ccgcccgcgg
     2581 actgctgctg cgccgcgcct ggagccgcgg ccccgcgctc gtcacccaga tcatggcgct
     2641 gcccgtcgcc tggacgctgc tgcgctccag cggcccgctg atcccggccg ggatcgcgct
     2701 cgcggtggtg gccgggacgg cgctggtcct gctggtcaac ccgacgacca ccgaagcact
     2761 cggcatccgg ggccgggaca gcgcgtaggc cgtgtccgga aagtcccgcc tggccgacgg
     2821 cgcctggcac ggcacatcgc cgcgttgtcg gagtcggccg agtacggccg gtagcgaccg
     2881 gtcctccgcc ttgcgatgca ccgaaccggc cgccgcgggc cccgccccgc gggcggacgg
     2941 cgccgcattc cggactcccc aggccgtggc cgggggtgtc ctcaatcgtc ggacggggtc
     3001 gaaatgagcc cgtccggcga ctgagggcga accatccacc gggcgggcgg tgagaccgcc
     3061 ccggccgcgg cccgagggcc cgtcactcct ccacgagcag cttctcgcgc agctgcgcca
     3121 gcgtccgtgc cagcagccgc gagacgtgca tctgggagat gccgacctcc tgcgcgatct
     3181 gcgactgcgt catgttgccg aagaagcgca gcagcagaat ccgcttctcc cgcggcggca
     3241 gatcctccag caggggcttc agcgactcgc ggtactcgac gctctccagc gcctcgtcct
     3301 ccgagccgag cgtgtccgcc accgccgggg actcgtcgtc cgtgtccggg acgtccagcg
     3361 acagcgtgct gtacgcgttg gccgactcca gcccttcgag gacctcttcc tcggagatgc
     3421 cgagacgctc cgccagctcg tgcaccgtcg gcgaacggcc gtgctgctgc gagagttcgg
     3481 ccgtagccgt cgtcagcgac agccgcaact cctggagacg gcgcggcacc cgcaccgccc
     3541 agcccttgtc acggaagtgc cgcttgatct cgccgacgac cgtgggagtg gcgtacgtcg
     3601 agaactcgac acctcgctcc ggatcgaacc ggtccaccga cttgatcagg ccgatcgtcg
     3661 cgacctgcgt cagatcgtcc agcggctcgc cgcggttgcg gaaccggcgg gccagatgct
     3721 ccacgagcgg cagatgcatc cgcaccagct gattgcgcag cagcgcccgt tcgggagagt
     3781 cctccggcag cttgcgcagc tcgatgaaca tcgcccgcgc cccgctgcgg tcatgtgggt
     3841 cgtgttgcct gtgctcgctc atcgtggccg cccgctctgc ctgcgcctgc tccgccccgg
     3901 ccgtccggcc gtcaagcccg tccaccggat ggggccgggc ctgttgctcc ggaatgcccg
     3961 acggcatgag cgccggatcc gccggaacct catgcccttc gcgcggatcc tgtgggaccc
     4021 gctcctcgtc acgcaccgga ccgtccccgt tcctcacgcc ggcccgggtc ccgcgccgcg
     4081 ttgtttgtac aggctgatgg cgaccgtgcg gtcgtcggcg accgtcgcgt cgaccttgcc
     4141 cgcgagcgcc gagagcacgg tccacgcgaa cgtgtcacgc tccggcgcgc gcccgtccgt
     4201 cgtcggcgcc gagacggtca cttcgaggga gtcgtcgatg agccggaaca cacagctgag
     4261 gacggagccc ggtacggcct gttggagcag gatcgcgcag gcctcgtcga ccgcgatgcg
     4321 caggtcctcg atctcgtcga gggtgaagtc caagcgtgct gccaggccgg ccgtagccgt
     4381 acggagcacg gacaggtagg cacccgcagc gggcagccgg acttccacga agtcctgggt
     4441 cccgggctcg cctgcgatct gggacaccct cacctccaag gtggcacaag cttctcaagg
     4501 gctccgggaa gggaaacccc ggagctcgcg ttacgtggtc ggcacggagc cggtctggac
     4561 tggcgacgct atcgcgatcc atggtcccgt gtcgcaggga cccccgggcc ggcaccgacc
     4621 ggtcgattac tcatagtagg catatgagca cggacagtgg ctagaggtgt gcgggaacca
     4681 attacgaaga accggcggag ggttgacgta cccagggctc agacgatcga accgtcgggg
     4741 aagcaccaac gccacgtctc accgggctcg aagctacgca tcacggggtg ccccgtatcc
     4801 ctgaaatgac gtgaggcgtg ccggtgcggt gacgagtcgc agcacccgac atggccgcag
     4861 accagacaga gccgaagctg tacgtggtgg ctgcccgaag cctcgcactc caggcaggtc
     4921 ccgctcagcg gctcgggttc ggggcgtggg aggtcggcaa cgtgctggca ctcactcatg
     4981 atggccagat tacgacgcta ggggaggacg tgggatggac ccgttgcagc tgatcgccct
     5041 ggtggcggga agcgcggtga tcgccgcagc gggccgaagg acgcccgttc cggccccgct
     5101 gctccttgtc acggctggac tcggcgcagc gtacgtgccg ggcgtgccca gctacgtact
     5161 cgacccgcac atcgtccttc ccctgctgct gccgcccctg ctgcacacgg ccgccgtgga
     5221 gagctcctat ctggacctgc gggccaatgt gcgggccgtc ggcctgctct ccgtgggata
     5281 cgtcctcttc gcgacgctcg tcgtcggcta tctcgcctat ctgttcatcc ccgagatgtc
     5341 gctgaccgcc gccctggtgc tcggcgccgt catcgcgccg ccggatgcgg tcgccgccac
     5401 cgcgatcgcc cgcaaactgg ggctgcccag ccggatcacg accatcctcc agggtgagtc
     5461 gctggtgaac gacgcgaccg cgatcaccgc gttcaaggtg gcgctcgcgg cggccgtcgg
     5521 ggaaggcgcg agctgggccg gcgggatcgg cgagttcgcg ctggcctccc tgggaggcat
     5581 cggaatgggc ctcgtgctga tggtgccgct ccactggctc cgcacgcatc tgcgggaggc
     5641 gctcctcctg aacaccctct cgctgctcat cccgttcgtc gcctacgcgg cggccgaaca
     5701 ggtgggtgcc tcgggggtgc tggccgtcgt cgtggtcggg ctctacctcg gacaccggtc
     5761 ctggcaggtc gacttcgcga cccggctcca ggagcaggcc gtgtggaaga tggtgtcctt
     5821 cctcctggag tccgtggtct tcgccctgat cgggctccag ctcccctatg tactgaaggg
     5881 gctcggctcc tacgggggaa tggaggtcgc cggttacgcc gtcggggtgt tcgtcaccgt
     5941 cgtcgtggtc cgctacatct gggtcttccc ggccaccttc gtgccgcgcc tgctgtcgaa
     6001 gcggatcagg gagcgagaac cggacacgaa ctggaaggcg ccgctggtcg tcggctgggc
     6061 cggcatgcgc ggtgtggtgt cgctggccat cgccttctcc atcccgctga ccacgcacga
     6121 cggcgacgcc ttcccgaccc gcaatctcgt cctcttcctg acgttcacca ccgtcatcgc
     6181 caccctggtc gtccagggcc tcacgctgcc gacgctgatc cggctgctga agctgccggg
     6241 gcgcgacagc tacgccgaga cgctggccga ggcgcaggcg cagagccggg cgtcggtggc
     6301 ggcggaacaa cggctcgacg aactgctcgc cgacgaacgc aacgccctgg ccgaaccgtt
     6361 ggcggaccgg ctccgcaacg tcctggagcg gcggcggaac tcggtgtggg agcggctcgg
     6421 cacggtcaac gaactgaccg gcgaatccgc cgaccgcacc tatcagcggc tgtccaggga
     6481 gatgatcggc gtcgaacggg acgttttcgt gacgctgcgc gacgagcggc ggatcgatga
     6541 cgagatgctg cggacgctgc tgcgcaggct ggatctggag gaggccgtgg cctaccgcga
     6601 ggagaccggc tgaccgcagt cgccgccgtc gccttcggcc gggtccggag ggcggccggt
     6661 gacgacggcg gcgaccgtgc tgccgggcgg gaaggcgccc tcctcggcga gggtggtcag
     6721 cccgtggagc atcttcgcca cgtagaggcg ctcgaccggg agcccgtgcc ggtcctcgaa
     6781 gtcgtcggcg aagtcgtcgg cggcgggtgt cgtacgggcg tagccgccgc cgtggaagcg
     6841 ctcgtccaga ctccagtcgc cccgggggcc gccgaaggcg gccagctgga gggcgcggac
     6901 ctccccggcc aggaagccgc ccttcagcac ggggaagccg acggcgcgct gccccggggc
     6961 gagaccggcg gccaggcccg cgagggtgcc gccggtgccg caggcgacac ccaccacgtc
     7021 ggccgccccg cgcagctccc gcccgagggc cgtacagccc cgcgcggcaa gggagttgct
     7081 gccgccctcc gggacgacgt agacacgctc gcggggcacc gcgagcccgt tggcggccgt
     7141 ctccaggatc tccctcagta cggagggctc ggtcttacgg cgataggtcg cccggtcgag
     7201 gaagcgcagc cgcatgccgt cggcggcgca cgcggcgagt gacgggttca gggggcgggt
     7261 ggccagctcg tcgccccgta cgacgccgac cgtcgcgaag ccgagcagcc ggcccgcggc
     7321 ggcggtggcg cgcagatggt tggagtacgc gcctccgaag gtgagcaggg cgaggtgacc
     7381 gccgccggag gcggcccgca ggttgggttc gagcttccgc cacttgttgc ccggcagggc
     7441 ggtgtggatc aggtcgtccc gcttgagcag cagccgtacg ccgcggcggg tgaagcgctc
     7501 gtcctcgacg gtccgcaggg gtgacggcag ccgtggccgc agggcggcga ggtcgagcgc
     7561 ttccggagtc acccgtccat tgtcgcgccg gtgaatgccg gccggcccgg ccgctctact
     7621 tcagacgttc gtcgatgcgc cgccgcaggc cccccatcga gacgccgcgc gggtcgatct
     7681 tgcccggctg ccactccagg tggccgatga ccgagggacc gttccagttg tggacgcggc
     7741 agacggcggc ggccgcggcc tccatggctt ccacctggac cgccggccac gggtccttgc
     7801 cgtcgcccag gttctcgcac tcgaagccgt agaagtgtct gttgccgtcg gtgttggcct
     7861 cgttgtccgg cggcagggtc ttctcggcga tcaccgcgcg caggacgtcg tcgtcgccgc
     7921 tgcccgcgtg gttggcccgg ccgtagccga cgagatggac tctgccgtcc ttggagatga
     7981 cgccgtggca cagcggcccc ggcagccccg cgtacccgtc acggcagatg cggacggtgt
     8041 tcgcggtgcc cttggtgacc gtgtggtgca tcatcacgcc gtggaccggg ccccagggcc
     8101 ccacgtggtt gcggttgtgc gtacgccagt cgccgacctc gacgaccgtc agaccctcgt
     8161 tcttcagcgc acggatgaag ctgctcgcag acatgggtgt ggccatggcc gcctcctgac
     8221 cggtggatgt ggagcgttgt gcatcggttc tcttcgctgg cctcttaccc ggacacgacg
     8281 gagtggacca tcgattcgca cgccgtacga gccgatccgg tcactttcgg ccgagcgtga
     8341 gccgtggatg acagaagccg taaacgtgcc ccgactgcgg agatccagtc ccactcattt
     8401 gtgtgatggc gcgacaacta cacgtgatgc aaagcttttc acgcaggtca gcccatgatc
     8461 gagagggaga ttcatgtcgg ttggtgacga ggtccgtacg gtggagcccc cttcccagca
     8521 gagtctggga acggccgcgg cgcggaacct ggcgaccacc acgaagtcgg cgccacagat
     8581 gcaggagatc acctcgcggt ggctgctgcg gatgctgccc tgggtgcagg tgcagggcgg
     8641 tacgtaccgg gtcaaccgtc ggctcagcta ttcggtcggc gacgggcgtg tgacgttcgt
     8701 gcagacgggc gaccgggtgg aggtcattcc ggcggagctg ggtgagctgc cggcgttccg
     8761 tgacttcgag gacgaggagg tgctggccga actggcgaac cgctgcgagc agcaggagtt
     8821 cgccccgggc cagaccgtgg ccgcggccgg tggcccggcg gaccgggtgt acctgctggc
     8881 gcacggcaag gtggagaagg tcggcgaggg gccctacggg gacgagacgg tgctcgaagt
     8941 cctcgccgac ggggcgtact tcggggatca ggcgctggtg gacgaggagg ccacctggca
     9001 gtacacggca cgcgcggcca cggcgtgcac cgtgctggtg ctgagccggc aggacgtgct
     9061 gaacctcgcg gagcgggcgc agtcgctgcg gggccatctg gacgcgctgg cgtccattcc
     9121 cgcgcagcgg accaacaagt acggcgaggc ggcgatcgag ctgtccgccg gccatgtcgg
     9181 cgaggcggtg gtgccccata cgttcgtgga ctacgagggg gcgccgcggg agtacgagct
     9241 gagcgtcgcg cagaccgtac tgaaggtcca cagcagggtc gccgacctct acaaccagcc
     9301 gatgaaccag accgagcagc agttgcggct cacggtcgag gcgctgcgcg agcgccagga
     9361 gcacgagctg gtgaacaacc gcgagttcgg cctgctgaac aactgcgact acggccagcg
     9421 gctccagccg cacgacggcg ctccgacccc cgacgacatg gacgagctgc tgtcccgccg
     9481 ccgcggttcg aagatgttcc tcgcgcaccc gcgggccatc gccgccttcg gccgtgagtg
     9541 caacaagcgg gggctcaatc cggccacggt ggaggtcggg ggccaccatg tgccggcctg
     9601 gcgcggtgtg ccgatcttcc cctgcaacaa gatcccggtc tcggacgccc ggacgacctc
     9661 gatcatctgt atgcgtacgg gcgagagcga gcagggcgtc atcgggctcc agcagagcgg
     9721 catcccggac gagatcgagc ccagcatgtc ggtccggttc atgggcatcg acgagcaggc
     9781 gatcatctcg tacctggtca ccgcctacta ctcggcggcg attctcgtgc cggacgccct
     9841 cggcgtcctg gagaacgtgg aagtgagccg ctggcggtga cgtgacctga gcgacgtctc
     9901 cgggtggggg ccgtccgtcc gtacggcggc cgggccccac ccggtacgcg cctgtcgtcc
     9961 accggttccc cagcccgccg cagaggaagt gaccgtgacc atgaccagca cggatgccgc
    10021 caccgatggc catgaggccg tggcgctcct ggagcgcagc cgtagcgtcg tccaacccga
    10081 actgcgcgcg gccgtcgagt cgttgccccc ggccgtacgc cgtgtcgcga gatatcactt
    10141 cggctgggag cgggccgacg gctcacccgt ggcgggcggt gcggggaagg cgatcaggcc
    10201 cgccctggta ctcgcggcag cacaggcact cggcggagag ccgcaccgtg ccgtaccggc
    10261 ggcggtcgcc gtggagctgg cgcacaactt caccctgctg cacgacgacg tcatcgacga
    10321 ggacccgacg cgaagacacc ggcccacggc ctggacggtc ttcggcacca ccgacgcgat
    10381 catcgccggc gacgccctcc aggcgctggc gatgcggctg ctggccgagg accgccatcc
    10441 ggcctcgtcc ccggcggccg tgcggctcac cgactgcgtc atcgagctgt gcgccggaca
    10501 gcaggcggac tgcgcgctgg agctgcgcgg gccgaacgac gtctcgctgg acgagtgtct
    10561 gacgatggcg atggccaaga ccggtgcgct gctgggcact tcgtgcgccc tcggcgcgct
    10621 gtacgcggac tccggcgacg aggaggtcgc ggcgctcgac gccttcgggc gcgaggccgg
    10681 gctggccttc cagctcatcg acgatctgat cgggatctgg ggtgaccccg accgtacggg
    10741 caagccggcc ggtgcggatc tggtcgccca caagaagtcg ctgccggttg tcgccgcgct
    10801 ggtctcgggc catccggccg ccgaggagct ggcggatctc tatctgcggc cgatggacga
    10861 ggcggccgtg gcgcgcgcgg cttcggcggt cgagcgggcc ggcggacgtg actgggcgca
    10921 ggagcaggcg gcggaccgga tgtcccgggc ggtccagcaa ctggccggag ccgtcccgga
    10981 tctgacaagg gcgggtgatc ttctggccct cgccgagtac gtcacgcgcc gcacgcggta
    11041 ggccggcgcg cgggccgcga tcgggggcag gcaaaagacc ttgcgtaacc actacaggtg
    11101 aagcactatg gatggagtgg taaaggccgc gcaccccgga tgtgctccgg gcggcggcca
    11161 ttggcatctt ctgtcgccca tcgcaaaaga ggacaggctt gcgcaagctc agctatttcg
    11221 tcgccgcgtc gatcgacggt ttcatcggcg accccagtgg tgaggctgct ttcttcaccc
    11281 gcttcgtgga cgaggagttc ctcgacttcc tcaagagcga gtatccggag accctgccga
    11341 cgcacggccg ccgtccgctc ggtctcgacc acctggagaa caagcagttc gacaccgtca
    11401 tccagggccg gcgcagctac gacctggcgc tgaaggacgg tgtcaccagt ccgtacgcgc
    11461 acatgcgcca gctcgtggcg tcgcggaccc tcgcgagccc cgacccggcc gtggagatcg
    11521 tctccggcga tctcgacgcg agaataaggg agttgaagcg ggaggacggt ctcgggatct
    11581 atctctgcgg cggcgcgaat ctcgccgccc agctgatcga ggaggtggac gaactggttg
    11641 tcaaggcgta tccgctcatc ctcggctccg gaatgcccat gttcggcacg gagttcgccc
    11701 tcaccgagtt cgagctggaa tcccaccgcg ccttcggcaa cggagtggtc gtcaggacgt
    11761 acggccgcaa gcggtgaaga cacccggcgg cgggtgtggg gagccgtgaa gcggtgaagc
    11821 ggtgacccac gcggcggcgg agcgtcccgt accgctacag tccgcgcatg acagcggagt
    11881 cgacggagtc atgggcgggc tggtaccggg accgccgtgg tgcggagccc atcgcgatca
    11941 gcgcggacgg gcggcaagtc cgcacccata taaggggagt tgcttacgag ggggccgatt
    12001 tctccgtgct cgaacccacg gaggcgggag gggtgttgtc gtcgtgtgtg ctggagtggg
    12061 acatacccat gcccgtcagt gcgggcggca cggttcaaca ggccacgctc agttgcctgc
    12121 tgacgctcgg tgagcgtccg gccggcacgc cttcggggcg cgccgagctg agcctcacgc
    12181 tgcgctgcgg cggagcggcc tacgagtcgg gcatcgtcgg aggagggttc cgtgacgccc
    12241 tcgaccggat caagcgacag ttgcccgacg acacggaatt cgagggcagg atcctggtga
    12301 acgcctgacc tccacgcccg gcatcctcgg aggtccgaac cgacccggca ggcgcacggc
    12361 gcctgccacc ggctgcccgg ctcggcggac ggcgaacgcg gcacgggcgt gccggtactc
    12421 gaccagtgag taccggcacg cccgattttg gcgcctgatc cggtgggggg ttcgcgatcc
    12481 gacgaccggc tgtgggaccg gcggctgatc gcgacggatc agcgacggat caagatgcct
    12541 tggccagcgc ggccgtgaag ccgttcgccc agaggctgtt gacctcgctg cgctcagccg
    12601 cgtccggctg cgagttggtg caggacgggc cggggccgcc gcccgacatc agcttgctgc
    12661 acggggccgt gtagttgtcc ggcaggccga gcacgtgccc ggtctcgtgg gcggtcacgc
    12721 gcagggagtc gtactgctgg ttctgcgcgt agtccaggaa gatgtagcca cggccgtgcc
    12781 cgtcggtgct cgcgtacgag ccacgcgggt cgttgccctc ttcgtaggtg aagtcggcgt
    12841 tgctgccctg ctggagctgc acgttggaga ccgcgctgtt ccagatctgg gtgctgctgg
    12901 ctatctgccc ggcgaacgac ggtgcgccgg aggcgtcgta gacgacggtg accgcgagcg
    12961 cgccggggtt ggcggcacgc ttctcggcga ccgacttcat gacggcctgg tagaaggcct
    13021 tggtcgcggc cgtgtccgcc gcagagccct cgtacgcggc gtacgaggtg gtgggcgcgt
    13081 cgctggtggg ggcagcggcg gcgacggggg cggcggtgag agcggtcgcg aaggcgagcg
    13141 agattccgca gatcgcggag acggccgtct tggggtatct catgtggggg gctcctactc
    13201 gtccgatgaa cgggttcggt agggatgagt gtcgtgcccc gcggcgccgt ggcggatgat
    13261 gccgaagggc gatagcacgg gagtatcgcc ccggcggacg ctcacccaat ttcccgtgca
    13321 tgacagccaa ttagcgccct ttgggtccct ggcgtggagc aaacggcagg cctactcttc
    13381 ggtacatgga gctggaggtc aggcatctgc gcgcgctgtg cgccatagcc gacgcgggaa
    13441 gtctgcacaa agcggcccgg cagctcggta tgagccagcc gtccctgacg acgcagctgc
    13501 gacggatcga gaactcgctg ggcgccgagc tgttctcccg tgaacgcacc ggctgccggc
    13561 ccaccctgct cggtcactcc gtgctcagcc gggcgcgtcc gctgatcgcg gggatggccg
    13621 tgctcgtcag cgaggcacgg gcggcggccg accggtccgc cgggccccgg ttgcggatcg
    13681 gctcgacggc gagccgcgcg ctcgcgggct ggctgcgcag gctgcgcgag cggctgccgg
    13741 gcacggacat ctcgctccag atggacgtct cggcgaacgc gctgctgcgg gaggtggccg
    13801 ggggcgggct ggacgtggcg ttcgtgcacg aggtcgaggg ctgccagctg cgcgtgccgc
    13861 cggggctcga ccggcgcgta ctggtcgaac gggagccgca gttcatctcg ctggcccggg
    13921 accatccggc ggccggccgg ccggtcgtcg agctggccga tctggcgagc gaccggtgga
    13981 tgatcgaccc gaccgtggac ggcgaatggg acggcctgcg ccgcgtactg agcgatgccg
    14041 ggctcaaccc gcccgttctg cacggggatt acctcaccgc ctcgtcgctg atcgccgtgg
    14101 gcgaggccat agcgccctgc cagcccacct cggtcccgcg cgaggacatg gtggtgcgtc
    14161 cgctgcgcga cgacccgctg ggggtgcggc tgctgctgtt ctcgcggccg ggagcgtacg
    14221 agggcgcggg catcgcgagt tcgggtacga gcccggacgc ggaccgcgcc ggtgacggtg
    14281 acggtgacgg tcccggcggc gccgaggtct acgcggacct ggaggcggcc taccgagagg
    14341 cggcgttgca ggccggcgtg taccgccagt ggctgacgcg caacaagagc cccctgctgc
    14401 acgcgcccgc tgcctgaggt ttcaggacac ccccccgagt gtgaggttag taattcacgt
    14461 aggcacctgc taacttttct ttgcatgtgc aggaggccgc gatgagccca cccgtgccca
    14521 cgggcgacga actggtgcgc gtactggcga cgttgtccaa cccccaccgg ctgcgcgtcg
    14581 tcgcggcgct cgccggggga cggaactacg tgagccggct ggccagggag ctggacatca
    14641 gcagggcgct gctccaggtc catctcaaga agctcgaagc cgccggtctg gtgacctcgc
    14701 ggctggagct gtcggaggac gggaaggcca tgaagttcta cgaggtgaac gcgttcgcgg
    14761 tcgttctgac gccgcaggac atcgtcaccg ccgtgcagac gctgagcagt cagagcagtc
    14821 agagcagtcg gagcagtcgg agcagtcaga aggacgagag agacgagaag ggggccactt
    14881 gatggacgac gagcaagcgt ggcaggaagt catcggagcg ataggcctgt tcgcgatcct
    14941 gctgatcgtg gtgacgctca ccctgtggca cttcaccgtt ggccgccggg ccagggaggt
    15001 cagggccgac gagaacgagt accgccagct cgccgcccag gcggtggagg gtcagcggcg
    15061 tacggagaag cagctcgccg acctcggccg gcagctcacc gatctccaga gccgcaccgg
    15121 atcgctggaa cggatcctca aggacgtcga gtagcccggc aaccgggcag aacacaaccc
    15181 cgggccgtcg agcggcaact cgacgacccg ggcacagaag gacgatccac ctcgcctcgc
    15241 ggcgagctcc acggatacga ccctccggaa gaaggagagc agctcatgct gcgccgaatc
    15301 aagtcagagc gcgccggact cgtcgagtcc gtcgccggct ggtccgccag aaaccgtacg
    15361 gcggccatcg ccgcgtggtt gctcctggtc gtgatcgccg tcatgtccgg ctccctgttc
    15421 cccggtgaag aggccagggc caccgacccc ggtgaggcgg gccggggcca gcggatggtc
    15481 tccgcgcagg acgccggtga ctcgatacgc gagaacgtga tgatccgggc cggcgccggc
    15541 gccgcccccg cgacccggcg cgccgccacg aaggacctgg tcgcggcgct gcgcgcggtg
    15601 cccgacgccg tacgggacgt ggggtctccg ctcggcgccc acggcgggcg ctgggtgtcc
    15661 ggggacggca tggccgacct cgtgaccttc gagatcgccg gtcccgacgc cgagttcggc
    15721 gcccacagac aggccgcgga cgccgcagtg gagaaggtga cgcggcagca ccccggggcg
    15781 cgcgtcgacc aggccggcga ctccagcctc gcgtcggcgg tcgatgacgt gatcaagagc
    15841 gacatgaggc gcgccgagac cacctcgctg cccctcaccg tcgtgatcct gctcgtcgtc
    15901 ttcggctcac tggcggccgc cgggatccct ctgctgctgt cggcgaccgc cgtcgccgcc
    15961 gcgttcggcc tgctggacac gctcggccgg tgggtgccct tcaacagcgc cgcgtccgcg
    16021 atcgtgctgc tcatcggcat ggccgtgggc atcgactact cgctgttcca tctgcgccgg
    16081 atccgcgagg agcgcgcggc ggggcacccc gtccaggagg cgctgcggat cgcgtcgcgc
    16141 acctccggcc acgccgtcct ggtgtccggt ctgacggtca tggtgtgcat gaccggcctg
    16201 ctgttcacag gcgtcgacgt gttcaagggg ctgacgctcg ggaccgtcct ggtggtcgct
    16261 ctggcggtgc tcggatcggt gacggcgctg cccgcgctgg tggccgcgct gggcgaccgc
    16321 gtcgatttgg gcaggatccc gtggctggga cggcggcgta cggcggcggg ccgctcccgc
    16381 ctctggacgg ccgtggcggg ccacgtcgta cgccgtccac tgctcaccgg cggcgtcgcg
    16441 gcgctcctcc tcgcggtcat ggcccttccg gcgttcggga tgcacctcca ggacgccacc
    16501 cagatccaga gcctgccgcg cggcgtctcg gccgccgcgg acgcgggcgc ccggatgcag
    16561 caggtcttcc ccggcgtgac cacgcccgct cgcgtggtgg tgtcggccga cggcccggag
    16621 atacgggcgg cggccgaccg gctgcacgag caggccgcgc ggagcgacgg ggcgctgcgc
    16681 gagccgatca cgatggtgcc ggtcggcgag gtgctggtga tacgggtgcc gttggcgggg
    16741 gccggtacgg acccgcggtc cgaacaggcc ctggagttcc tgcgggagag ggcgctgccc
    16801 gcgaccgtgg gggccgtgga gggcgtggac cgggtcgagg tcgcggtcgc gggccggacc
    16861 gccatgccgt acgacttcac ccggcaggtg aacgcgcgga cgccgctggt cttcgccttc
    16921 gttctcgtcc tggccttcgt cctgctggcc gtcgccttcc gctcgctcgc cctgccgctg
    16981 gtgtcgatcg cgctgaacct gctgtcgatc ggcgcggcgt acggggtgct cgtcgcggtc
    17041 ttccagggcg gccggctgga gtcactgctc gacttcaacg cctatggggg agtggtgagt
    17101 tggctgccgc ttttcatgtt catcattctc ttcgggctga gcatggacta ccacatcttc
    17161 atcctgagcc ggatccgcga gcggtggacc ggttcaccgg ggggccgcga cgcctcgcac
    17221 gaggcgatcg tcggcggcat cgccgccagc gcgggtgtcg tgaccggcgc ggccgccatc
    17281 atggtcggcg tcttctcggt cttcacgacg ctgtcctcga tcgagtacaa gatgctcggc
    17341 acggggatgg cggtggcgat cctcatcgac gccaccgtcg tgcggggcgt gctgctgccc
    17401 gcgtcgctca cgttgctggg ggaccgggcc tggacgatgc cggggcggtg gggccggggc
    17461 gggtcgggga gctcggccgg ccgtcatgag tacggcgcga gcacggaacg cgcctggtcg
    17521 cgggcgaatc cgacggcgtc ggggaagatc ccgaggccgt gagcgacgag cgcgccctcg
    17581 tgcaggagca tgagcgtacg ggcgaggcgg tcggccgcct cggacccgat ggcctcgccc
    17641 ggcgccgtga cctcccgggc gagcgtggtg aacagctcca gcatccacgc cttctggccg
    17701 gtgatgaccg cgtacgccgg atgctccgga tcgtcgatct ccgcatgggc gttgaccatg
    17761 ctgcacccac gcgagccgtt ctcggccacc cagtcccgcg aggccgcgaa gaccgcgagg
    17821 acatgctcgg cgggtgacgg gggagcggcg gccagccgct cgtccaggaa ggcgcgccag
    17881 cgctcgtcgc ggccggccag gtactcgacg acgatctgct ccttcgagcc gaaccggtcg
    17941 tagagcgtct tcttggtgac ccccgcctcg gcggcgatga ggtcgacgcc gacggcgtgg
    18001 atgccgcgtt cgtagaagag ccgcgacgcc gcgtccaggg cgcggcgcgc gccgggggtc
    18061 aggacgatcc ggtggggtgg ttgcggcctt ctcgtcccgc gcgccggcgt cggctgctcg
    18121 ggggtgctgc tcgtgatccg gctcatggtg aaaagtatac cgctctgtat agtgaaggag
    18181 gtgagtaaac agatcggtat acctgtctcc tcgcccaagg gcggtgtcct gccatgaacc
    18241 tcctcctcgc cgtcgcgttc gtcctctgct ggagctccgg cttcatcggc gcgaagctcg
    18301 gcgccggcag cgccgacgcc gtcacggtcc tgatgtggcg gttcctgccc ctggcgctgg
    18361 tcctgggggc ggtcgccgtc acccgcgccc gcgccgcctg gcgcgggctg acggcgcgcg
    18421 acgtgctgcg ccagtgcgtg atcggcgcgc tgtcccagag cggctacctc ctcaccgtct
    18481 actacgcgat ccagctcggc gtctccagcg gcaccaccgc cctgatcgac gggacgcagc
    18541 cgctcgtcgc gggcgcgctg gccggacccc tgctgcggag tcacgtctcc gggcgccagt
    18601 ggctgggcct gtgcctgggg gtgacgggcg tgctcgtcgt gacgtcggcg gacgcggcgg
    18661 ccgcgcaggg cgtcgagccg tgggcgtacg gggtgccgtt cctcggcatg ctgtcgctgg
    18721 tggccgccac cttcctggag agccgctccc gcacggtggt cgcgccctcc gtggcgatga
    18781 cgatccactg cggtacgagc gccgtcgtct tcaccgccct cgcggcggcg gcgggcgccg
    18841 cggtgccgcc cgccgagacg tccttctggg tggccgtcgg ctggctggtg gtcctggcga
    18901 cgttcggcgg atacggcctc tactggctgg tcctgcgccg ctccggggtg atgcgggtga
    18961 acaccctgat gttcctcatg gcgcccgtca cggcggtctg gggagcgatc atgttcggcg
    19021 aacccttcgg cccgagcacg gccgccggcc tcgccgtcgc gctgctcgcg gtggtggtcg
    19081 ttcggggcgg ggcggcccgt acggcgcccg gcggaaactc cggtgacgtg ccggcccgtc
    19141 gcgccgacaa tggcacgtgg gtgtgaccgc gcgccttctc cgcgccggtg ccccgatgcc
    19201 tcgcagaccc accaacaggc aaaggagcga ccgcatggtg cggcgcagag ttgtccccgc
    19261 cctcttcccg ccgcccggct acgcgcacgc ggcggtcgtc gagaccgacc ggcgcctggc
    19321 gttcctggcg ggctccgtac cgctcgacaa ggacggcaca ctcgtcgggc cgggcgactt
    19381 cgcggcccag accgaacagg tcctggcgaa tctcgagacc gcgctgcgcg ccgtcggcag
    19441 cgatctggac cgggtggtga ccaccgacgt gtacgtggtg tcgtcggacc cggcggacct
    19501 gagccgggtc tgggacgtcg tccacgcctc gggtctcacc accgggccgc acacgtccac
    19561 actgctcgga gtcgggtgcc tcggctacac cgggcaactg gtggagatca cggcggtggc
    19621 cgaggtcgcc gaagccgagg acctcgcact tccggccggt tgacgccggg acgccgacgc
    19681 cgccggtccg ggggcgcgga cggcggcgtc gacgcggctt gtgcggtccg cagcggtccg
    19741 gcgtggtcca cagcggtccg cagcggctcg ggtggctcgg gtgggctcgg gtggctcgct
    19801 cagccgtcgg cgagcatgcc gtcccggagc ttggccaggg tccgggccag gattctggag
    19861 atctgcatct gcgagacgcc gaagcgctcg ccgatctggg actgggtcag ttcctgcccg
    19921 tagcgcagct caaggatctg gcgctcccgc tcgtccagtg tgctcaacag cggcgccagg
    19981 ctgtggaagt cctcgaccag ctccatggcg gggtcgcacg cgccgacgaa gtcggcgacg
    20041 gacgcaccgc tcctgccggg ggcgcccgtg ccggaatcgg cgggcaggtc gagcgagtcg
    20101 gagttgtacc cgttggcggc gatcagccct tcgatgatct cctcctcgct cagcttcaga
    20161 tgctcggcca actccctcac cgtcggctcc cggtcgagcc gcacggcgag ctggtccttg
    20221 gcccgcgcga gctgtatccg caactcctgg agccggcgcg gcacatgcac ggcccaactg
    20281 gtgtcacgga agaagcgctt gatctcaccg acgatgtacg gcacggcgaa cgaggtgaac
    20341 tccacctcgc gcgacagctc gaaccggtcg atggccttga tcagaccgat cgtcccgacc
    20401 tggacgatgt cctccagctg gtcgtcccgg ttacggaacc gctgggcggc gaacctgacc
    20461 agcgacaggt tcatctcgat cagtgtgttg cgcgcgtact ggtactcgtg cgtgccctct
    20521 tcgaggacct gcaactgctg gaagaacacc ttcgacaact cacgcgcgtc cctgggcgcg
    20581 acctgacccg cgtcctcgat ccacggaagc tccccgaccc gtggccccgt cagaggttcg
    20641 gcggttctcg tgaactgggt ggacatggac atgatgttga ttccctcccg gatcggcgag
    20701 cggggggctc gccgacgcga cgtgtgccct gccctccccc ggctatgcgc gctccgcaca
    20761 cattttctcc ccgtcgtcgc ccccgaaaag aagaccgcac ccgctccggc atggacgcca
    20821 ctctcggcgt ccgcggaacg ggtgcggaac ggcaggcatg atgaccggcg aaagtgcagg
    20881 tcagggggcc cagccagggg tcaggccttc ttggtctccc agaagatctt gtcgatctgg
    20941 gcgatgtagt ccagggcctt ctggcccgtc gccgggtccg tcgagccctt cgcggccgac
    21001 agcgccttca gggcgtcgtt gaccagctgg tgcagctccg g
//
