LOCUS       NZ_CP048397            33119 bp    DNA     linear   CON 08-MAY-2024
DEFINITION  Streptomyces sp. S4.7 chromosome, complete genome.
ACCESSION   NZ_CP048397
VERSION     NZ_CP048397.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. S4.7
  ORGANISM  Streptomyces sp. S4.7
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7920066)
  AUTHORS   Bekiesch,P., Zehl,M., Domingo-Contreras,E., Martin,J.,
            Perez-Victoria,I., Reyes,F., Kaplan,A., Ruckert,C., Busche,T.,
            Kalinowski,J. and Zotchev,S.
  TITLE     Viennamycins: new lipopeptides produced by Streptomyces sp. S4.7
            isolated from the rhizosphere of Edelweiss (Leontopodium nivale
            subsp. alpinum)
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7920066)
  AUTHORS   Bekiesch,P., Zehl,M., Domingo-Contreras,E., Martin,J.,
            Perez-Victoria,I., Reyes,F., Kaplan,A., Ruckert,C., Busche,T.,
            Kalinowski,J. and Zotchev,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-FEB-2020) CeBiTec, Uni Bielefeld, Sequenz 1, Bielefeld
            33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8; canu v. 1.6
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 57.8x
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_010384365.1-RS_2024_05_06
            Annotation Date                   :: 05/06/2024 10:27:30
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,027
            CDSs (total)                      :: 6,939
            Genes (coding)                    :: 6,650
            CDSs (with protein)               :: 6,650
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 289
            CDSs (without protein)            :: 289
            Pseudo Genes (ambiguous residues) :: 0 of 289
            Pseudo Genes (frameshifted)       :: 103 of 289
            Pseudo Genes (incomplete)         :: 223 of 289
            Pseudo Genes (internal stop)      :: 23 of 289
            Pseudo Genes (multiple problems)  :: 52 of 289
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:05:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3959738
            Orig. end                         :: 3992857
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP048397.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Zotchev Lab, University of
            Vienna, Austria.
            Annotated using prokka v1.11 from http://www.vicbioinformatics.com.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..33119
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NI-siderophore"
                     /region_number="11"
                     /rules="IucA_IucC"
                     /tool="antismash"
     cand_cluster    1..33119
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..33119
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[14000:19119](+)"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      14001..19119
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     misc_feature    complement(55..70)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     gene            <1230..1997
                     /locus_tag="SSPS47_RS17620"
                     /old_locus_tag="SSPS47_17860"
                     /pseudo=""
     CDS             <1230..1997
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009720721.1"
                     /locus_tag="SSPS47_RS17620"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_17860"
                     /product="AAA family ATPase"
                     /pseudo=""
                     /transl_table=11
                     /translation="KVIVWDGYNRPKDEAAFAKLMEITQEWTLAGRPVEGLRAQIALQN
                     PPYHLGRKLRVSRNNVARASRFTVSYEVRPEDIPANEWLIAAYGDVAETVLEWWKNDID
                     DEARDWITKRTLERLIKLHLAGQPLMLGLIHLGEGEFTPVPLTGLEARLAGIGQEVALG
                     FRELVRDVDLWEKRLAVASEVSSEGTNDTDVVHRVLANAELSQLKRHGEVVARLLRHMP
                     PKLRATHLVGQTPARQSYWVGVLARMKELAASS"
     gene            complement(2104..2247)
                     /locus_tag="SSPS47_RS17625"
     CDS             complement(2104..2247)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SSPS47_RS17625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_164251931.1"
                     /transl_table=11
                     /translation="MRSSGSRVAVNSSSRDGGNGTRLSSSLTVSSRMRGISARVSSRST
                     RA"
     gene            2281..3813
                     /locus_tag="SSPS47_RS17630"
                     /old_locus_tag="SSPS47_17865"
     CDS             2281..3813
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SSPS47_RS17630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SSPS47_17865"
                     /product="hypothetical protein"
                     /protein_id="WP_164251932.1"
                     /transl_table=11
                     /translation="MFQRLAGQGDPALATGLYGEREWDRTPAQRDAVWEGAVATAGDPG
                     WRAQDGLPAKLLASRRQELLEPALLSPFPEVVAHARSVLDRRAGSDRGAGSGTRPTGPS
                     NTTPRKNRQSWERHPWTTTELIGDFRDKGFHGTTELPAAPGALDWDALVAEHRAEPFRA
                     SALAALWGHPDCPQELVLAAFEANRNNTLPDGAVHWPMLASPTLGMLEDHALSKLLGRG
                     LVSGAVPAERVLRETAPARRILCALPHGHGPVRDALVAQVARLGPDLAPWRAVYALLPR
                     FSGTVTELVDAALAEAPKHRDKPWPKPMGPEFPSRGTSIGRAAWLYLYDAAGHGTRCAL
                     VEHMDLRAIQQLLLWHRPSPELRAYIVRSRGASALAGIASSWDTRPEVIEELIPYNESE
                     VNAALFLHTDLTPAQRRHVLSGRRWRDGGSADTPAADRPDSRPRRPSPFCPGRWRRVTR
                     PAPRRYGPHAARSPHSPMSTSRTTRRAGRSRSAWPRTSRAHCRTCCSRRARW"
     gene            complement(3842..4270)
                     /locus_tag="SSPS47_RS17635"
                     /old_locus_tag="SSPS47_17870"
     CDS             complement(3842..4270)
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018382145.1"
                     /locus_tag="SSPS47_RS17635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_17870"
                     /product="protein-tyrosine phosphatase family protein"
                     /protein_id="WP_164251933.1"
                     /transl_table=11
                     /translation="MTTTWEPTAAGVLRLPSGRLVRGRGLRRPLPAGPAPAFALHLLGK
                     EPPAVDWTARWVRWPDFRLPADRAGAAEALREALERAGDERVEIACGGGRGRTGTALAC
                     LAVLDGVPNARAVAYVREHYSRHAVETPWQKRYVSRFA"
     gene            complement(4417..5217)
                     /locus_tag="SSPS47_RS17640"
                     /old_locus_tag="SSPS47_17875"
     CDS             complement(4417..5217)
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF016550.4"
                     /locus_tag="SSPS47_RS17640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_17875"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_164251934.1"
                     /transl_table=11
                     /translation="MSDSVRPGTNVMPTVPNSARIWNYAQGGQDNYQVDRELGDVMMGD
                     FPEIKTAAMESRAFQERVADHVVREFGIRQLLDLGTGIPTGSGTHGMAQKVAPESRVVY
                     VDNDPVVLNHASALRSSPEGRIHYFQQDFRDVEAVLEGVSTTLNLDEPVALLVLSTLGH
                     FPPAEAADLVASYTSRFVSGSYLAVCDTIETPGVLRMQEHYVQADPEGAYLARAPEQIA
                     DCARGLALLPPGLRPLPELVLPAGTTAPAGAEDCVQWGFLAVKP"
     gene            complement(5214..6173)
                     /locus_tag="SSPS47_RS17645"
                     /old_locus_tag="SSPS47_17880"
     CDS             complement(5214..6173)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040183.3"
                     /locus_tag="SSPS47_RS17645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_17880"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_343234890.1"
                     /transl_table=11
                     /translation="MTEFDRRVSWSAPNGEEKTLATRGREEGPVSQPRSGPTVALRCFG
                     ADLRRRREAAGMTLQSVAEKIKKDRVTPARWENAETVPNPRMVGVLLDLYETPADERAE
                     VLRALAEAKKPGWWHPWREVAEVGVIDLESAATSIRSYAPGVLPDLLQTTEYAEALMSL
                     RNPYEDPAVRRLRLELLEARKEHTIGDGNGRDRAGLWVLLEEATLRRRVGGPGVMARQL
                     DYLESRIADVRSSVAIQVIPPRVPHPLAISLCGHLEILRFKEFGMGERLIQIGLHPSMT
                     LITDDSDAVENYRMAVDVTSGFAPPRFTPLPLTSKDFG"
     misc_feature    complement(6169..6179)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     gene            6324..6791
                     /locus_tag="SSPS47_RS17650"
                     /old_locus_tag="SSPS47_17885"
     CDS             6324..6791
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SSPS47_RS17650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SSPS47_17885"
                     /product="hypothetical protein"
                     /protein_id="WP_164251936.1"
                     /transl_table=11
                     /translation="MHVSLPAVPEQIQVARRIVRKELAGLGWPSAKIAACEEIAVQLAR
                     HAIGVVGVSGYYLGVTKRPGPQGDAVAIRVSVTILDSPAAPATVPAQGRPAEPTGPAEP
                     AGRVEFDEDNSRLADVLTKRCGTRVSIVAQQGSWAASATLTAEVPCVGARP"
     gene            7150..7836
                     /locus_tag="SSPS47_RS17655"
                     /old_locus_tag="SSPS47_17890"
     CDS             7150..7836
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SSPS47_RS17655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SSPS47_17890"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_164251937.1"
                     /transl_table=11
                     /translation="MADVSRSVLVVSGASGSAESVAAAYARQDDWVGFLYERGTPPDEL
                     YNVRCDVSDGLQLDAAVSEFETGHGVVDVLVVDADRHDRYGEETAHSAAAGTRARANAI
                     IGRTLPGMREAGHGRIVLIASTKGLGRGSALSGGAPHADLMSLAWHLVHECRGSDITVN
                     VITYGSPEGATRQGRAHRAQQIANLAVHLTRPEATDTGAVIPIEVLGAIPSLGPARTDG
                     ASYRGH"
     gene            complement(7946..8392)
                     /locus_tag="SSPS47_RS17660"
                     /old_locus_tag="SSPS47_17895"
     CDS             complement(7946..8392)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018514186.1"
                     /locus_tag="SSPS47_RS17660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_17895"
                     /product="PPOX class F420-dependent oxidoreductase"
                     /protein_id="WP_164251938.1"
                     /transl_table=11
                     /translation="MTTSSAPSTPFDPRALLAQSRLGVLATIKSDGRPQLSPVMPFYDE
                     EAGILYVSMTEGRAKTANLRRDPRAALEVTSPDGWSWATAEGPVTLIGPGTDPDGREVE
                     ALVDYYRRASGEHPDWAEYRAVMVSDRRVLMAMTVDHVYGAKIA"
     gene            complement(8438..9310)
                     /locus_tag="SSPS47_RS17665"
                     /old_locus_tag="SSPS47_17900"
     CDS             complement(8438..9310)
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1100: 3-hydroxyisobutyrate dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003991934.1"
                     /locus_tag="SSPS47_RS17665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_17900"
                     /product="NAD(P)-binding domain-containing protein"
                     /protein_id="WP_164251939.1"
                     /transl_table=11
                     /translation="MNAAAPVTVLGLGLMGQALAEALLREGHATTVWNRTAAKAEPLVA
                     KGAELADSVADAVAASQLVIICVLDYDAVHGLLDPVAGSLDGRVLVNLTSGTSEGARET
                     ARWAAGHGATYLDGAILTDPDGVGTADAVVLYSGPRATFDAHEPTLRLFGGAATHLGDD
                     HGLSSLYDVAVLGMMWGVLNSFLQGAAVLGAAGVDASVFAPLAAKSVKMIADWVPGYAE
                     QIDKGAYPAVDATLNTHLASMNHLVHESEFLGVSAEFPKFVRALAERSVANGHGTEGYA
                     SMIELFREP"
     misc_feature    complement(9340..9355)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.15"
                     /tool="antismash"
     gene            9392..9781
                     /locus_tag="SSPS47_RS17670"
                     /old_locus_tag="SSPS47_17905"
     CDS             9392..9781
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018835161.1"
                     /locus_tag="SSPS47_RS17670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_17905"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_164251940.1"
                     /transl_table=11
                     /translation="MLIGELSRRTSVHAHQLRYYEAQGLLEPERGANGYREYGSDAVVT
                     VTQIRRLLEAGLSTEEIAFLLPCATGAGPDLLPCDDVLEMLRARQRGLDDHIDTLLRSR
                     RTLQEFIDATERRASPYARSGACEA"
     misc_feature    9937..9955
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: strong, score: 35.53"
                     /tool="antismash"
     gene            10152..11396
                     /locus_tag="SSPS47_RS17675"
                     /old_locus_tag="SSPS47_17910"
     CDS             10152..11396
                     /EC_number="5.1.1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_DAP_Arg_deC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264: diaminopimelate decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012500.4"
                     /locus_tag="SSPS47_RS17675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_17910"
                     /product="alanine racemase"
                     /protein_id="WP_203557867.1"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 2.4e-15,
                     bitscore: 55.2, seeds: 500, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 5.8e-34, bitscore:
                     116.2, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVQFPPSAAPLVAHPVDVLPAPVRSRLLEMARGAEPVSAYVYDG
                     EVAAARARELRAALPDWAAVYYAVKANSFPGIVHALAPHVDGFEVASVSELELALTAAG
                     FADTPAVVAAGPAKSVPVLTALVRARVEAINAESLLELHRISRIAVAEGVTARVALRVN
                     PAGIPISGSLHMGGAPSQFGVAEPDVPDVLAAAGKLPGLDIVGFHIHAASNNLDADTHA
                     AYLRWCVEWSVRTAAATGIELRHIDIGGGIGVAFEGEAPFDMARFGELTALVEPPVGVK
                     VVLEPGRFLVADCGWYAAEVTDVKASFGEWFAVLRGGINHFQLPTSWDIVHNVAVLPVD
                     AWEAGEGCPRPAAEHTRVTVVGELCTPEDTLLRDVYVERVRAGDLVVFPNAGSYGWEFA
                     MHAFLGHPVAGRQLL"
     gene            11432..12421
                     /locus_tag="SSPS47_RS17680"
                     /old_locus_tag="SSPS47_17915"
     CDS             11432..12421
                     /GO_function="GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (54-230). E-value: 1.8e-20.
                     Score: 65.2. Matches aSDomain:
                     nrpspksdomains_SSPS47_RS17680_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014139311.1"
                     /locus_tag="SSPS47_RS17680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_17915"
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_164251941.1"
                     /sec_met_domain="Aminotran_3 (E-value: 2.5e-19, bitscore:
                     67.9, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVPAATLSASGYPAGDPDTGDAGAPGDAHSILERQRARESSART
                     YARSFPIVPARAHGMTIEGVDGRRCLDCLSGAGTLALGHNHPVVREALRRTLDSGAPLH
                     VLDLATPEKDDFTDALFETLPKAFADRARVHFCGPAGTDAVEAALKLTQTATGRRGVLA
                     FTGTFRGNTLAMATGAATLRYVTREGLAERSATVGARMSARLDGLRSELPLIGDVRGRG
                     LMIGVEIIDPEGPSDSCGARPVAPGLAARVQEGCLKRGLILELGGRFGSAVRLLPPLVI
                     TDEEAESVPERLTEAIAEVAKAPGKPKPSKAPESVDGAGAVGVSGRAA"
     aSDomain        11594..12121
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SSPS47_RS17680_Aminotran_3.1"
                     /evalue="1.80E-20"
                     /label="SSPS47_RS17680_Aminotran_3.1"
                     /locus_tag="SSPS47_RS17680"
                     /protein_end="230"
                     /protein_start="54"
                     /score="65.2"
                     /tool="antismash"
                     /translation="ARAHGMTIEGVDGRRCLDCLSGAGTLALGHNHPVVREALRRTLDS
                     GAPLHVLDLATPEKDDFTDALFETLPKAFADRARVHFCGPAGTDAVEAALKLTQTATGR
                     RGVLAFTGTFRGNTLAMATGAATLRYVTREGLAERSATVGARMSARLDGLRSELPLIGD
                     VRGRGLMIGVEII"
     gene            12418..14004
                     /locus_tag="SSPS47_RS17685"
                     /old_locus_tag="SSPS47_17920"
     CDS             12418..14004
                     /GO_function="GO:0016830 - carbon-carbon lyase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019752 - carboxylic acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180: Decarboxylase, pyridoxal-dependent"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014139312.1"
                     /locus_tag="SSPS47_RS17685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_17920"
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="WP_239064947.1"
                     /transl_table=11
                     /translation="MTTEALGAAVEDVLRALRPETGTELSGGVGGAAALEPLVRDVLGA
                     LAAGAARRGGPVAAGAPAGIEAAVAEVFRTAGGPRALGELTELLSYGSADPADPACAAH
                     LHCPPLAVAVAADLAVSALNPSQDSWDQAPAATALETLLLQELAAMLGYDPAEAAGVLT
                     SGGTESNLMGLMLARDRVLGAATGRQIELTGVSRTGAGVGPGAVAGARPRILASAAAHF
                     SVQRAAALLGLGEDSVIPVAVDSQLSMKSGALAAKLEQCVERGQLPVAIVATAGTTDTG
                     AIDPLRECAELAAEYGAWLHVDAAYGGGALLSDRLAPLLDGIELADSVSLDWHKLGWQP
                     AAAGVFLVRKSQTYASLARRAVYLNPADDEEAGYPSLLGLSLRTTRRADAFKIAVTLRT
                     LGREGLGRLVDACHELAVAGARAAAAHPRLELHGGGGPGGGDPVLTAFLFRYVPAEGAA
                     DGARTDHLNASLRRRLLREGGAVVGRTELPGEGPGRVRLKLTLLNPHATVAEVERLLDA
                     VVAAGVAEEGL"
     gene            14001..15842
                     /locus_tag="SSPS47_RS17690"
                     /old_locus_tag="SSPS47_17925"
     CDS             14001..15842
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016099.4"
                     /locus_tag="SSPS47_RS17690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_17925"
                     /product="IucA/IucC family protein"
                     /protein_id="WP_164251942.1"
                     /sec_met_domain="IucA_IucC (E-value: 6.1e-68, bitscore:
                     227.7, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGAGGWRCAAPDPAPQSPEGLDRSAGVDPLDLPDPLRAADSVAV
                     ETLLRAYVRETGTDVPGSGSLLYLALPCSALTLRVRVLYRSVTGWHRFGSVRVVTSGKG
                     GSLPADVGLVAAALVRESTLGRGAPPYLGADAVGRIVNSAVRTGAHLVRRRGETPGTRG
                     VTPFLDAEQALLLGHPFHPAPKSREGASDSELDAYSPELRGSFPLHWFAVHPDVLVGES
                     ADGRTPAELLRPLTDGLGLSVPDGMTVVPAHPWQARDVLARPAVRPLVDAGLLRPLGPA
                     GPHWYPTSSVRTVHRPDAGVMLKLSLGMRITNSRRNNLRGEMRLGVRAARLLAAGPAGR
                     LRAEHPEFGILRDSGWVSAGVDGDAETGLETAVRDNPFRGGAGDGLCVAGLVAERTGPG
                     DGSPPAHRALLSEAVARTARAHGVSTAEASARWLAAYLDVLAVPLIRLRAWYGIALEPH
                     HQNTLVALGADGLPRAGWYRDSQGYYVAASHAADTERLLPGAADGLDLVFDDAFVDERV
                     AYYLGINNLLGLVGAFGALGLADEGDLLRVLRARLERLRAAEPGAKALLDLLLDAPVLR
                     CKGNYLTCVDGLDELVGDVESQSVYVDLTNPLAEAQR"
     gene            15839..17308
                     /locus_tag="SSPS47_RS17695"
                     /old_locus_tag="SSPS47_17930"
     CDS             15839..17308
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1080: lysine/ornithine N-monooxygenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014138454.1"
                     /locus_tag="SSPS47_RS17695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_17930"
                     /product="SidA/IucD/PvdA family monooxygenase"
                     /protein_id="WP_203557868.1"
                     /transl_table=11
                     /translation="MTESEPESESSTPVYDLVGVGIGPFNLSLAALADGAPELRTLFLD
                     AKPAFSWHPGLLMEGTTLQVPFLADLVTMVDPTSPWSYLNYLRHHDRMFPFFFSERFHI
                     PRREYDAYCRWVTEGLASCQFDAHVDRLGWDERRELFVVAHRTADGALTRVLARQVVLG
                     VGTNPVVPEPLRPLLADSAHTGRVLHSADYRTHRARLAACDDVTVVGAGQSGAEVALDL
                     LRHQDGAGAGGPYVRWLARTNAFAPMEYSKIGLEHFTPDYIRYFRALPEDRREQLVREQ
                     WQLYKGVSDETLGELHDEMYERTIGGTDPRAALHPGVEIVATEVAGGDYVLTCRHAQQD
                     ALFEIRTSAIVSATGYAATRPAFLDGEEGEGGEGGERGLGTLVDWDAQGRYRIDGEYRV
                     ALDPGVSGTLYVQNAEMHTHGVGAPDLTLGAWRAATILNAVAGRTVLRVPERAAWTTFG
                     VPRPGSGTDRAHPHLPAPASAHSAVHEENVR"
     gene            17305..19119
                     /locus_tag="SSPS47_RS17700"
                     /old_locus_tag="SSPS47_17935"
     CDS             17305..19119
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018896105.1"
                     /locus_tag="SSPS47_RS17700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_17935"
                     /product="IucA/IucC family protein"
                     /protein_id="WP_164251943.1"
                     /sec_met_domain="IucA_IucC (E-value: 1e-67, bitscore:
                     226.9, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQLDRDAWEQAGRRLLIKAVEEFAYEELLVPLPDAGTAGQYRLD
                     LGDDVHWTLRAARGTFGTWRVEPGSLLRHPDVGDGREAGPERLLLDARGVLGWDGVTTA
                     EVLRELTATRRADAEAITRALPAAELADLDHLELEAYQDGHPCMLLNKGRLGFAASDAA
                     AYAPESAPAVRLLWAAVHSDLATYSGVPGLDAERLLAEELDPATRERFAAVLAEECARN
                     GLSGEEFSWLPVHPFHWDEAVATLFAPYLAEGRIVALGQSDDRYRPLQSIRTLANIDHP
                     HRRNVKVPLLIRNTLVWRGLSTEPTEAAPDVSAWLHSVRDADPYLSQELRIHPLGEVAA
                     VAVGHPLYESVKDAPYRYHELLGAVWREPVAALLDTDAGERARTMAALLKTGSDGRALT
                     AELVERSGLGPTAWLERFFGALLPGLLHYLYRYGVAFCPHGENTVVLFDRDEIPVGTAV
                     KDFAEDVNLLPGARPEYATLSERADRVLLRWPAHELAHSLLSAVFAGHFRFFAPLCSAQ
                     LGVPEDEFWALVRAEIERYHARFPELADRFDSYGLLAPSFDRVALNREQLLGGGFHDRS
                     ERDEGFDVVHGTVPNPLAAAPARTGERI"
     gene            19116..20528
                     /locus_tag="SSPS47_RS17705"
                     /old_locus_tag="SSPS47_17940"
     CDS             19116..20528
                     /EC_number="6.3.1.-"
                     /GO_function="GO:0004356 - glutamine synthetase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016827016.1"
                     /locus_tag="SSPS47_RS17705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_17940"
                     /product="glutamine synthetase family protein"
                     /protein_id="WP_164251944.1"
                     /transl_table=11
                     /translation="MTGERPSPYERLRADAAAGRVEEVIVAVPDIQGRLQGSRLSVPYF
                     LDEIDGAGESGGDGDGDSDGFGACVYLLASDVEMDTRPGYAIDAWRTGFGDFLLRPDPA
                     TLRTHLPWDEGTALVIADAHWPGAGGSPVAVAPRHVLRTQLDRLAERGLTALAGTELEF
                     LVFLDTYRAARETRYQGLTSGTAYNVDYSLQGLSGIEPVVRRIRREMGRAGLAMETARG
                     ECHAGQYEIVFRYAEAMTTCDNHVFFKNGAKQIAAQEGVALTFMPKFDEGEGNSCHIHL
                     SLRGEDGTAVLADASADDGMSALMRHFVAGQLACLPDFALLMAPNINSYKRLQPGAFAP
                     TGITWGRDNRTCPIRVVGTGSSMRIEHRVPGGDANPYLAVAAAVAAGLYGIEHRLELPP
                     PHRENALADPSVPRLPGTLTEALHRWESSGIAAKVFGEPVVAHYAQAARTELAAFETSV
                     TDWERMRGFERL"
     gene            complement(20756..21727)
                     /locus_tag="SSPS47_RS17710"
                     /old_locus_tag="SSPS47_17945"
     CDS             complement(20756..21727)
                     /GO_process="GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642935.1"
                     /locus_tag="SSPS47_RS17710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_17945"
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_164251945.1"
                     /transl_table=11
                     /translation="MSTHLTRRIGVAAAATALAVSLSACGGDGDESSDKAAPGGTHTVT
                     TAMGEVKVPRDPKRVVVLDTDALDSAITLGITPVGATTAVADTPFSTYLPQEKLGDIKS
                     VGLIAEPNLEAIAALKPDLILSSKVRDEKNYKPLSEIAPTVFSDTTGPNWRENFELHAD
                     ALGKTAEARTIADAYDTRVKELTTTFGGPEAAKKTTFGFVRFVEGADTRLYLNDTFVGS
                     IYGDLGVGRPANQDKTGFSLDVSPEKMDEANADVVFYSTYGDAKKANETDIIGGPLWKN
                     LDAVKSGKVFKVDDNVWMLGIGYTGAGKVLDEIEKNYGAAAG"
     misc_feature    complement(21775..21793)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.41"
                     /tool="antismash"
     misc_feature    complement(21891..21907)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 23.75"
                     /tool="antismash"
     misc_feature    21967..21981
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 24.85"
                     /tool="antismash"
     gene            22003..>22143
                     /locus_tag="SSPS47_RS35480"
                     /pseudo=""
     CDS             22003..>22143
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019328205.1"
                     /locus_tag="SSPS47_RS35480"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="GntR family transcriptional regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGERAAGPLHLRLVRALRAAVVDGRIAPGSALPPSRALAADLGCS
                     RW"
     misc_feature    22285..22303
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.78"
                     /tool="antismash"
     gene            22323..23021
                     /locus_tag="SSPS47_RS17720"
                     /old_locus_tag="SSPS47_17950"
     CDS             22323..23021
                     /GO_function="GO:0070273 - phosphatidylinositol-4-phosphate
                     binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017530.4"
                     /locus_tag="SSPS47_RS17720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_17950"
                     /product="GPP34 family phosphoprotein"
                     /protein_id="WP_164251946.1"
                     /transl_table=11
                     /translation="MDFATNTPTNTPVETTLGEQLLLLSLDDESGAEKESMNVSYAIAA
                     ASLVELVLAGRVEVNEDQVTVRDAAPLDDPTLDVALADISGEDKRKPRKTKEWIEHLKK
                     GAVAGTTGNLVAKGLIREEKKKVLGLFPVRRYPEADGSVESALRQRLDEVVMRGAAPDE
                     RTASLVALLHGAKLHGLLYEKPQLATAKVNMEKVAHGQWAGPAVRQAVKAAEDALTAIV
                     LLTVVTTTVL"
     misc_feature    22355..22370
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.99"
                     /tool="antismash"
     gene            complement(23049..24512)
                     /locus_tag="SSPS47_RS17725"
                     /old_locus_tag="SSPS47_17955"
     CDS             complement(23049..24512)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016638358.1"
                     /locus_tag="SSPS47_RS17725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_17955"
                     /product="hypothetical protein"
                     /protein_id="WP_239064948.1"
                     /transl_table=11
                     /translation="MKTDERGHPLGDTGTDTPTGAHPDADAAEDADVHGHERTGRPHRR
                     DLVAAGVGLALVTTAALVGGAIQRAEGSLQVNWPPLLGTWDPRVGPGTPAALAVAVLIV
                     AYGPGLAARLPWRALLLTTWSAALAWTFSLALVDGWHWGVARRLTTKNEYLTVIDRFSD
                     IGATLRGFSDHIVIGPPGNWPAHVAGHPPGATLTFVWLDRIGLGGGSWAGVWCIVVGGS
                     AVAAVLVTLRALTDERTARRAAPFLALAPAAVWVGTSADGYFAGVAAWSLALLALAATR
                     TARFPAAAALGAGLLYGWTCYLSYGLTLMALPGLGILVLARTARPLPLVLAGALVVPVA
                     FTLAGFNWWEAYHELVVRYYQGAGGVRPYWYWIWGNLAATTLAVGLATAAGLGRVFVLA
                     PRAVRRVRPARAASTPTLRLAVLVLAAALAIVAADVSGMSKAETERIWLPFMLWLIPAT
                     ALLPGRRRWWLAGQAAVALLVNHLVFTGW"
     gene            24626..25945
                     /locus_tag="SSPS47_RS17730"
                     /old_locus_tag="SSPS47_17960"
     CDS             24626..25945
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014157946.1"
                     /locus_tag="SSPS47_RS17730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_17960"
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="WP_164251947.1"
                     /transl_table=11
                     /translation="MDHPPRLSKRPVGALPPLPTDPTFWRSPVRGVRFTAVLGLVLLAG
                     LTLLFVTGLLSYAAYNPDLASVNDKTPDRGWLGFYLFDWPTHPYWLYRLIQGLHVTVGI
                     ALIPVLLAKLWSVIPRLFTLPPVTSLAHALERISLVLLVGGALFEFVTGVLNIQLDYLF
                     PGSFYRLHFYGAWVFFGAFVAHAALKMPKALRAIRSGELRSGRTGGGTGAGAHRAAGTE
                     DDLASPAPAPPTLSRRGAFAVVGTGSLFMLLTTAGRSFDGPLRRTALLAPHGWQDPGGG
                     PNGFQINKTAAAVGVRAADTAGDRWRLVVSGPAGDVRLSRAQLLAMDQHTSELPIACVE
                     GWSTSNQSWRGVRLRDLAALAGYPADAPGVFVESLQARGSFRSGALRDNQVRDGRSLLA
                     LRVNGADLSLDHGFPARIIVPAAPGVLNTKWVTRLTFGAL"
     gene            complement(26310..27134)
                     /locus_tag="SSPS47_RS17740"
                     /old_locus_tag="SSPS47_17970"
     CDS             complement(26310..27134)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003949905.1"
                     /locus_tag="SSPS47_RS17740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_17970"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_239064949.1"
                     /transl_table=11
                     /translation="MSTTDTGTDAPATGTADTGTEAAAWSTDPYADALRAGRGPLFLRR
                     TDGWLLPLDVERWCARADAADLSALHRCEGAVLDIGCGPGRLVAALAARGRQALGVDVS
                     EAAVERTLRLGGTALHRSVFDPLPGEGRWGTVLLVDGNIGIGGDPAGLLRRAAGLLRHG
                     GLIIAETAPVDIDERVRVRVDDGRHPPADGARATGSHFPWARLGTPALLRYGRAIGWQP
                     VDQWEAAGRPFVALRRSTARVTRQSAEHTNSAAVTSSQRARNPSGDRAAYGS"
     gene            complement(27131..27784)
                     /locus_tag="SSPS47_RS17745"
                     /old_locus_tag="SSPS47_17975"
     CDS             complement(27131..27784)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010064424.1"
                     /locus_tag="SSPS47_RS17745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_17975"
                     /product="DUF2064 domain-containing protein"
                     /protein_id="WP_239064950.1"
                     /transl_table=11
                     /translation="MTSPTTTLLVIAKEPLPGRVKTRLTPPFPPADAARLAEAALADTL
                     RTVRALPARRRVLVLEGRPGPWLPPGIDVVPQCAGGLDERLAAAFESCKGPTLLVGMDT
                     PQITPDLLAPALGPAGWDGCDAWFGPADDGGFWALGLAAPESAPPDLIRGVPMSAPDTG
                     AVQRRRLVRAGFTVRDLPPLRDVDSAADAEYVASAAPDGQFAATLRRLTPVGAR"
     gene            complement(27781..28524)
                     /locus_tag="SSPS47_RS17750"
                     /old_locus_tag="SSPS47_17980"
     CDS             complement(27781..28524)
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971022.1"
                     /locus_tag="SSPS47_RS17750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_17980"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_164251948.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 7.4e-20,
                     bitscore: 70.2, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNLSDLTADVVLPCLDEAAALPWVLEHIPVGWRAIVVDNGSTDG
                     SADVARSFGATVVHEPRRGFGAACHAGLLASDAEYVCFCDCDASLDPGLLTGFVRQVAL
                     GETDLMLGRRRPQGRGTWPAHARAGNLALSRMLRRRTGVTLRDLGPLRAARRADLLALG
                     ITDQRSGYPLEMVVRAADAGLRVNEADVPYRPRTGRSKVTGTWRGTWHAVRDMRAVLSR
                     PPAQSLRRTSTAPNTVPNAPAEAAK"
     gene            28648..29619
                     /locus_tag="SSPS47_RS17755"
                     /old_locus_tag="SSPS47_17985"
     CDS             28648..29619
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018547777.1"
                     /locus_tag="SSPS47_RS17755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_17985"
                     /product="response regulator transcription factor"
                     /protein_id="WP_164251949.1"
                     /transl_table=11
                     /translation="MQSNPIGGDAGHGANGQAPAHVLVVDDDPTVAEVVAGYLDRAGHD
                     VARAADGPSALARFARRRPDLVVLDLMLPGMDGFEVCRRMREQGGPVPVIMLTARGDEE
                     DRVLGLETGADDYVTKPFSPRELVLRVGSVLRRARLPVPVPGTSPAAGVLRTAALSLDP
                     AARRATREGAELALTLREFDLLAFFLRHPGRAFSREELMSEVWGWDFGDLSTVTVHVRR
                     LRAKIEHDPARPRLIQTVWGVGYRLAEPEDMAAGGSAGAGAGRPPQDTRPAPGAEGVPD
                     IPAGASASSPDTPPRSPDTPPRSPDPSPGSDPSPGSRRSARP"
     gene            29616..30722
                     /locus_tag="SSPS47_RS17760"
                     /old_locus_tag="SSPS47_17990"
     CDS             29616..30722
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018099804.1"
                     /locus_tag="SSPS47_RS17760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_17990"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_164251950.1"
                     /transl_table=11
                     /translation="MKDMLLIALIAFLGAAAAGLLGALTLRLFRRRSLVVSVTVVAAVA
                     VTAMLAGTLAVAWAMFLSPHDLSVVTTVVAMAAVVSLVTAVLLGRWMVARSRDLTLAAR
                     SFGDGGVFAAPVEPATAELDALTRELAATSAKLDSSRERERALETSRRELVAWISHDLR
                     TPLAGLRAMSEALEDGMAADSPRYLRQIRTEVERMNDMVGDLFELSRIHAGSLTLTPTR
                     ISVYDLVGDALAGADPLARELGVRLVGDRIDAVPVEVDSKEMSRVLGNLLINAIRRTPA
                     DGTVAVAARHGQGGVVLSVTDGCGGIPEEDLPRVFDTGWRGSDARTPPAGAGLGLAIVR
                     GIVEAHAGRAAVRNVAGGCCFEVTLPAA"
     gene            30841..31671
                     /locus_tag="SSPS47_RS17765"
                     /old_locus_tag="SSPS47_17995"
     CDS             30841..31671
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231: carboxyvinyl-carboxyphosphonate"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972779.1"
                     /locus_tag="SSPS47_RS17765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_17995"
                     /product="isocitrate lyase/phosphoenolpyruvate mutase
                     family protein"
                     /protein_id="WP_164251951.1"
                     /sec_met_domain="PEP_mutase (E-value: 8.6e-68, bitscore:
                     227.1, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPPGSPSRPALGFHELHHRTAPLVLPNAWDVPSALAFVDAGFEA
                     VGTTSFGVASGLGRPDGGRSTRDANVALARALAPLPVHVSVDIEDGYSDDPDEVAAYVS
                     TLAAAGADVADVAGVNIEDSTAETLIDPAAHAAKVAAVKRRCPEVFVNARVDTYWLGQD
                     ATVDSTLERAARYIEAGADGVFVPGVTEPGVLRELAAAVTVPLNVLAVPALSLTELAGL
                     GVRRVSTGSLPYRAALHAAVRVADTVRGGGGALPEATPYPQLQARLVDYASRLA"
     gene            complement(31630..32715)
                     /locus_tag="SSPS47_RS17770"
                     /old_locus_tag="SSPS47_18000"
     CDS             complement(31630..32715)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (66-258). E-value: 3e-07.
                     Score: 21.7. Matches aSDomain:
                     nrpspksdomains_SSPS47_RS17770_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010643495.1"
                     /locus_tag="SSPS47_RS17770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_18000"
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_164251952.1"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.7e-05,
                     bitscore: 22.7, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLVTGGAGFIGSEVVGALVSRGHEAVVFDALLPSAHGGAPPRP
                     TREGERLVVGDVRDREAVAGALAGVEAVCHQAAMVGLGKDFADAPAYVGCNDLGTAVLL
                     AAMADAGVPALVLAGSMVVYGEGRYDCPRHGVVRPGPRAAADLDAGRFEPNCPDCGSPL
                     VPGLVAEDAPVDPRNVYATTKLTQEHLASSWARATGGRAVSLRYHNVYGPGMPRDTPYA
                     GVASFFRSALARGEAPRVYEDGGQRRDFVHVRDVAAANVAALDAVCAGGPSGFAAYNTG
                     SGEPHTIGEMAAALASAHGGPAPVVTGEYRLGDVRHVTADSRALREELGWKPEVGFADG
                     MAEFATAPLREPGRVVDEPRL"
     aSDomain        complement(31942..32517)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SSPS47_RS17770_NAD_binding_4.1"
                     /evalue="3.00E-07"
                     /label="SSPS47_RS17770_NAD_binding_4.1"
                     /locus_tag="SSPS47_RS17770"
                     /protein_end="258"
                     /protein_start="66"
                     /score="21.7"
                     /tool="antismash"
                     /translation="LAGVEAVCHQAAMVGLGKDFADAPAYVGCNDLGTAVLLAAMADAG
                     VPALVLAGSMVVYGEGRYDCPRHGVVRPGPRAAADLDAGRFEPNCPDCGSPLVPGLVAE
                     DAPVDPRNVYATTKLTQEHLASSWARATGGRAVSLRYHNVYGPGMPRDTPYAGVASFFR
                     SALARGEAPRVYEDGGQRRDFVHVRDVAA"
     CDS_motif       complement(32632..32706)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SSPS47_RS17770_0001"
                     /evalue="5.70E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="SSPS47_RS17770"
                     /protein_end="28"
                     /protein_start="3"
                     /score="12.6"
                     /tool="antismash"
                     /translation="LVTGGAGFIGSEVVGALVSRGHEAV"
ORIGIN
        1 cggaaacggg catgggcggg gccacgggcg cgggagtgga cccggacgtc gccggggacg
       61 cggaagtgac gttcgccgat gtcttccggg aggccctgcg ccgccgcggt ctctcgctgg
      121 agcgcgtacg cgaccggctc gaagcacagg gaatcggcgt cagcctcgcc accctcagtt
      181 actggcagcg cgggcgcagc cagcccgaac gcgccaggtc cctgcgcgcc gtcgacgcgc
      241 tggaggacat cctcgccctg cccgccggcg ccctccgctc tctcctgcgc cccggccggc
      301 cgcgcggccg tacggcgtcg gacctgctcg atctctccgc ctcgcaccgc gtcttcggtg
      361 agaactccga cgtggaacag gccctcggcg cggacttcgc gcgcttcaac gaggacgtca
      421 cctccctggt catccacgag accgtccatc tcgacgccga gcgccgcata cggcagatgt
      481 cggtgaacca ggtgctgcgc gccacccgcg acggcgcgag ccggctgacc gccgtgcatg
      541 tcatcgacga cccggcgacg gagtcggtcg acgtcgccgt acgctgcggc aggctcggcc
      601 gggtggagtt cctgccggag cggcggagca tcgtgacgga gatcctgttc ggcggtgaaa
      661 tggccaagaa cgagacggtg gtggccgact acacgatctc gctctccccg agccgcgagg
      721 tctcgacgta ccacgagcgc cgcacgcggg tgagcctgcg ggagtacctg ctgcacgtgt
      781 acttcgaccc cgacgcgctg ccggtgagct gccaccgcta ctaccgcgaa cggatcggcg
      841 cggagaagac gagcagcagg cagatcgcgc tggacgtctc gcacacggcg cacatgctgc
      901 cgccgaagtg cccggcgggg atacacggca tgtcgtggga gtggcccgcc tgaccttcgc
      961 gcccgacgcc cgcgcgcccg acgcccgcgg tccgacgcgc gcgcgcccgc gcgcccgcgg
     1021 tccgacgccc gcgcacccga cgcccgcgca cccgacgccc gcgcgcccga cgcccgcgcg
     1081 cccgacgccc gcgcgcccga cgcctgcgcg cccgcggtcc ggcgcccgac gggatgtcag
     1141 accccggcgc tagggttttt cgcatgaccg aagcggccgt gaccacgacc acgagcgtcg
     1201 ccgatctgcg ggactggcga cggctgttga aggtgatcgt ctgggacggg tacaaccggc
     1261 ccaaggacga ggccgcgttc gccaagctga tggagatcac ccaggagtgg acgctggccg
     1321 ggcggccggt ggagggcctg cgcgcgcaga tcgcgctcca gaacccgccg taccacctgg
     1381 gcagaaagct ccgggtcagc aggaacaacg tggcgcgggc cagccgcttc acggtcagct
     1441 acgaggtgcg gcccgaggac atcccggcga acgaatggct catcgcggcg tacggcgatg
     1501 tggccgagac cgtcctcgaa tggtggaaga acgacatcga cgacgaggcc cgtgactgga
     1561 tcaccaagcg gacgctggag cggctgatca aactgcatct ggcgggccag ccgctgatgt
     1621 tgggcctgat ccatctgggc gagggcgagt tcacgccggt gccgctgacc ggactcgaag
     1681 ccaggctggc cgggatcggg caggaagtgg cgctcggctt tcgggagttg gttcgggacg
     1741 tcgacctctg ggagaagcgt ctcgccgtcg cgtcggaggt ctcctcggag gggacgaacg
     1801 acaccgacgt ggtgcaccgg gtgctcgcca acgccgaact gtcccagctc aagcggcacg
     1861 gcgaggtcgt ggcacggctg ctgcgccaca tgccgccgaa gctgcgcgcc acccatctcg
     1921 tcgggcagac gccggcccgg cagagctact gggtgggcgt gctcgcccgg atgaaggagc
     1981 tcgcggcgtc ctcctgagac gcgtgtccgc cctttcggac cgccgcccca ccgcagccac
     2041 gtcgcccgaa cgcccgagag agtcccagat gcgccacgcc gaacacaccg tcgtatccgc
     2101 cgcctacgcc ctggtcgacc gggaactgac ccgcgcgctg atgccgcgca tccgggagga
     2161 gacggtcagg ctgctggaca gccgcgtccc gttgccgccg tccctgctgg aggagttgac
     2221 cgccacccgg gacccggagc tgcgcacggc gctcgtcgcc tccgccgggc acgcgacgac
     2281 gtgttccagc ggctggccgg gcagggtgat cccgcgctgg ctaccggtct ctacggcgag
     2341 cgcgagtggg accgtacacc cgctcagcgc gacgcggtgt gggagggcgc ggtggccacg
     2401 gccggggacc ccggctggcg ggcgcaggac ggtctgccgg cgaagctgct ggcgtcccgg
     2461 cgccaggagc tgctggaacc ggccctgctc tcgcccttcc ccgaggtggt ggcgcacgcg
     2521 cggagcgtcc tcgaccgcag ggccggctcc gacaggggcg cgggctccgg gacccggccc
     2581 accgggccgt cgaacaccac cccccggaag aaccggcagt cgtgggaacg ccacccgtgg
     2641 acgacgacgg agttgatcgg ggacttcagg gacaagggct tccacggcac gacggagctg
     2701 ccggcggcac cgggcgccct ggactgggac gccctggtcg cggagcaccg tgccgagccg
     2761 ttccgcgcct cggcactggc ggctctgtgg gggcacccgg actgcccgca ggagctggtc
     2821 ctcgccgcct tcgaggccaa ccggaacaac acgctgcccg acggcgccgt ccactggccg
     2881 atgctggcga gccccactct cggcatgctc gaagaccacg cactgtccaa actcctcggc
     2941 cgcggactgg tctcgggcgc cgtccccgcc gagcgcgtcc tgcgggagac ggctccggcc
     3001 cgcaggatcc tgtgtgccct gccgcacggc cacgggccgg tacgggacgc cctggtcgcc
     3061 caagtcgccc ggctgggacc ggatctcgcg ccctggcggg ccgtgtacgc gctgctcccg
     3121 cggttctccg gcaccgtcac cgaactcgtg gacgccgcgc tcgccgaggc gccgaaacac
     3181 cgtgacaagc cctggccgaa gccgatgggg cccgaattcc ccagccgtgg gacgtcgatc
     3241 gggcgcgcgg catggctgta tctctacgac gcggcgggtc acgggacgcg gtgcgcgctc
     3301 gtcgagcaca tggacctgcg cgccattcag caactgctgc tctggcaccg gccgtcccct
     3361 gaactgcgcg cgtacatagt ccggtcgcgg ggcgcgtcgg ccctcgcggg catcgcgtcg
     3421 agctgggaca cccgccctga ggtgatcgag gagctgatcc cgtacaacga gtccgaggtc
     3481 aacgccgcgc tcttcctcca caccgatctc acccccgccc agcgccgtca cgtgctgtcc
     3541 ggccggcgct ggcgggacgg agggtcggcc gacacccccg ccgccgaccg accggattcc
     3601 cggcccaggc gaccatcgcc tttctgtcca gggcgctggc gccgggtgac tcgcccggca
     3661 ccgaggaggt acgggccgca cgccgcgcgg tcgccgcact cgccaatgag cacctctcgg
     3721 acgacccgga gggctgggcg ctcgcgctcc gcctggcccc ggacttcgag ggcacactgc
     3781 cggacctgct gctcgcgtcg ggcgcggtgg tgagctgagg ggcccggggc ctgtgcggcg
     3841 gttacgcgaa gcgcgagacg tagcgcttct gccacggggt ctcgaccgcg tggcgcgagt
     3901 agtgctcgcg gacgtaggcg acggcccgcg cgttcggcac gccgtccagg acggcgagac
     3961 aggccagggc cgtgcccgta cgccctcggc cgccgccgca ggcgatctcg acgcgctcgt
     4021 caccggcccg ctccagtgcc tcgcgcagcg cctccgccgc cccggcccgg tcggccggca
     4081 gccggaagtc cggccagcgc acccagcggg ccgtccagtc gacggcgggc ggctccttgc
     4141 cgaggaggtg gagcgcgaag gcgggcgccg ggcccgccgg gagggggcgc cgcagtcccc
     4201 ggccgcgtac gagccggccg gagggcagtc gcagcacacc cgctgccgtg ggctcccaag
     4261 tggtggtcac ggagccgagg ttagccgggc cagccgggcc cgtgcggcga aacggccgac
     4321 gccgcccagc agcggtcggc accggtgccg ggaggcgggc cggaaccggt gccgggcgca
     4381 cgggtgtccc gactcggacc tgtactcgtc ccgtggctac ggcttgaccg ccaggaatcc
     4441 ccactggacg cagtcctcgg ccccggcggg agcggtggtc ccggccggca ggaccagttc
     4501 cggaagcggg cgcagtcccg gcgggagcag ggccagtccg cgggcgcagt cggcgatctg
     4561 ctcgggcgca cgggcgagat aggcgccctc ggggtcggcc tgtacgtagt gctcctgcat
     4621 cctgagcacg ccgggcgtct cgatcgtgtc gcacaccgcg aggtaggagc cggagacgaa
     4681 gcggctcgtg tagctcgcga cgaggtcggc cgcctcggcg ggcggaaagt ggccgagcgt
     4741 ggagagcacc agcagggcga ccggctcgtc caggttcagg gtcgtcgaca caccctccag
     4801 cacggcttcc acgtcacgga agtcctgctg gaagtagtgg atcctgccct cgggtgaact
     4861 tctcagcgcg ctcgcgtggt tcaggacgac ggggtcgttg tcgacgtaga cgacgcgtga
     4921 ctccggtgcc accttctgtg ccatgccgtg ggtgccgctg ccggtgggga tgcccgtgcc
     4981 caggtccagg agctggcgga tgccgaactc ccgtaccacg tggtccgcca cccgctcctg
     5041 gaaggcccgc gactccatgg ccgccgtctt gatctccggg aagtcgccca tcatcacatc
     5101 gccgagctcc cggtcgacct ggtagttgtc ctggccgccc tgcgcgtagt tccagatccg
     5161 cgcggagttg gggacggtgg gcatcacatt ggttccgggg cgtacggagt cgctcatccg
     5221 aagtccttac tcgtcagggg caggggagtg aaacggggcg gtgcgaaccc gctggtcaca
     5281 tccaccgcca ttcggtagtt ctcaactgcg tcggagtcgt cggtgatgag cgtcatggac
     5341 ggatggaggc cgatctggat cagcctctcc cccatcccga actccttgaa gcggagaatc
     5401 tccaggtggc cgcagaggct gatggccagg gggtgcggta cgcgcggcgg aatgacctgg
     5461 atggccaccg aagaacgtac gtcggcgata cggctttcaa ggtagtccag ttgacgggcc
     5521 atcactccgg gaccgcccac ccggcgccgc agtgtggcct cctccagcag cacccacagg
     5581 ccggcccggt ccctgccgtt cccgtcgccg atggtgtgct ccttgcgggc ctccagcagc
     5641 tccagccgca gacggcgtac ggcggggtcc tcgtacggat tgcgcaggct catcagggcc
     5701 tccgcgtact ccgtggtctg gagcaggtcc ggcagcacgc cgggcgcgta ggagcggatg
     5761 ctggtcgccg cggactccag gtcgatgaca ccgacctcgg cgacctcgcg ccaggggtgc
     5821 caccagccgg gtttcttcgc ctccgccagc gcgcgcagga cctcggcccg ctcgtcggcg
     5881 ggcgtctcgt agaggtccag caggacgccg accatgcggg ggttcggcac cgtctccgcg
     5941 ttctcccagc gcgccggtgt cacccggtcc ttcttgatct tttcggcgac gctctgcagc
     6001 gtcatgcccg ccgcttcgcg ccgacggcgc agatctgccc cgaaacaccg caaagcgacc
     6061 gtggggccgg atcgtggctg actcaccgga ccctcctcgc gtccgcgggt ggcgagggtc
     6121 ttttcctctc cgttcggcgc gctccacgat acccgccgat cgaactctgt cacgttgcag
     6181 agtgtggggt cggatggata tgctgaagtc tggagtttcc ctacgcggta ccccccccag
     6241 accgccgcgc agggttcggg aaccgacccc gccggacacg ccgagaggcg tgacagggcg
     6301 gggggtcacg gagaaccgat gccatgcacg tctcactacc ggccgtaccg gagcagatcc
     6361 aggtcgcgcg ccgtatcgtc cgcaaggagc tggccggtct cggctggccg tcggcgaaga
     6421 tcgccgcctg cgaggagatc gctgtccagc tggcccggca cgccatcggt gtcgtgggcg
     6481 tcagcggcta ctacctcgga gtgacgaagc gccccgggcc gcagggcgac gccgtggcca
     6541 taagggtcag cgtgacgatc ctggactcgc ccgccgcgcc ggcgacggtg ccggcgcagg
     6601 gccggcccgc cgagccgacc ggaccggccg agcccgcggg gcgcgtcgag ttcgacgagg
     6661 acaactcccg cctggccgac gttctgacga agcgatgcgg gacccgggtc agcatcgtcg
     6721 cgcagcaggg cagttgggcg gcctcggcca ccctcacggc cgaggtgccc tgcgtcggcg
     6781 cgcggccgtg agaggccggt cgaccgccgg atcgccgccc ggcgagcact gtcggtcggg
     6841 cccccctgac caacccgtct tggagaggct gctgtggacg cactgagggg tgccgcatcc
     6901 gatgacccca cgtgggagcc caggcgtgag accaccgcgg cgcacaccgg agcacgtcac
     6961 gcgagcagat catccgtcgg gcaaccgccg cccccggcac acgcggcgcc ccccgcgcac
     7021 acggcgaatc tcgccgccgg tcaccgtctg ccgcggtctc cgcgcgcccg caggtggacg
     7081 gcctggtacc ggccgacgag cgcggatccg gtcccggtac gcgaccgtgg agtcacgcac
     7141 ggtggggaag tggcagacgt gagccgttcg gtactggtcg tcagcggagc cagcggaagc
     7201 gccgagagcg tcgccgccgc ctacgcccgc caggacgact gggtcgggtt cctgtacgag
     7261 cgggggaccc cgcccgacga gctgtacaac gtgcgctgcg acgtgagtga cggactgcaa
     7321 ctggacgccg ccgtatcgga gttcgagacc gggcacggag tcgtggacgt cctcgtcgtg
     7381 gacgccgacc gccacgaccg gtacggcgag gagaccgccc actcggcggc ggccggaacg
     7441 cgggcccgcg cgaacgcgat catcggccgc acgcttcccg gtatgcgcga ggcgggccac
     7501 ggacggatcg tcctgatcgc ctccacgaag ggtctgggcc gaggctcggc cctgtccggc
     7561 ggcgccccgc acgcggacct gatgagcctg gcctggcacc tggtccacga gtgccgcggc
     7621 tcggacatca ccgtcaacgt gatcacatac ggctcccccg agggcgccac ccgccagggc
     7681 cgcgcccacc gcgcccagca gatcgcgaac ctggcggtcc acctgacccg cccggaggcc
     7741 accgacacgg gcgcggtgat cccgatcgag gtcctgggcg cgatcccctc cctgggcccg
     7801 gcccgcacgg acggagcgtc ctaccggggc cactgaccgc cgcgtctcca gggggcccct
     7861 cagccccgga ggcgcggcac cgcgccggga acggacctcc gcggcggggc tccccgagtc
     7921 gagccccgcg cgcgaggccg ccgcgtcagg cgatcttcgc cccgtacacg tggtccaccg
     7981 tcatcgccat cagcacccgg cggtcggaca ccatcaccgc gcggtactcg gcccagtcgg
     8041 ggtgttcacc ggaggcgcgg cggtagtagt ccacgagtgc ctcgacctcc cggccgtcgg
     8101 ggtcggtccc cgggccgatg agggtgaccg ggccctcggc cgtcgcccag gaccagccgt
     8161 cggggctggt gacctccagg gcggcccgcg ggtcccggcg caggttcgcc gtcttcgcgc
     8221 ggccctcggt catcgatacg tagaggatgc ccgcctcctc gtcgtagaag ggcatgacgg
     8281 gggagagctg cgggcggccg tccgacttga tggtggcgag cacgccgagg cggctctgcg
     8341 cgagcagtgc gcgcgggtcg aacggcgtgg acggtgcgga tgatgtggtc atgtccggct
     8401 ccaagtcgtg acgggacgtc ggctgttccc gcgtcctcta tggctcgcgg aagagttcga
     8461 tcatcgacgc atacccctcg gtgccgtggc cgttcgccac ggaacgttcc gccagggccc
     8521 tgacgaactt ggggaactcg gcgctgacgc cgaggaattc actctcgtgg accaggtggt
     8581 tcatcgaggc cagatgggtg ttcagggtgg cgtcgacggc cgggtacgcg cccttgtcga
     8641 tctgctccgc gtagccgggg acccagtccg cgatcatctt gacgctcttg gccgcgagcg
     8701 gtgcgaacac cgaggcgtcg acgcccgccg cgccgagtac ggcggcgccc tggaggaagc
     8761 tgttcaggac gccccacatc atgcccagca ccgccacgtc gtacagcgac gacaggccgt
     8821 ggtcgtcgcc gaggtgggtc gcggccccgc cgaagagccg cagggtcggc tcgtgggcgt
     8881 cgaaggtcgc gcgcggcccg ctgtagagga cgacggcgtc cgccgtgccc acgccgtccg
     8941 ggtcggtcag gatcgcgccg tcgagatacg tggcgccgtg ccccgccgcc caccgcgccg
     9001 tctcacgggc tccctcggac gtgcccgacg tcaggttcac caggacccgg ccgtcgagag
     9061 agccggccac cgggtcgagg agtccgtgca cggcgtcgta gtccaggacg cagatgatca
     9121 cgagctggct cgccgcgacg gcgtcggcga ccgagtccgc gagctcggcg cccttggcga
     9181 cgagaggttc ggccttggcc gccgtacggt tccacacggt cgtggcgtgc ccctcgcgca
     9241 gaagggcctc ggccagcgcc tggcccatca gacccaggcc cagcacggtc acgggtgcag
     9301 cagcattcat tcttcgctcc tcgatatggc ttggtgcgcg tgacagaatc ttcaacgttc
     9361 ataccgatat gaaggtcaag ggggagccgc cgtgctgatc ggggagctga gccggcggac
     9421 gagtgtccac gctcatcagt tgcggtacta cgaggcccag ggcctgctcg aaccggagcg
     9481 cggagccaac ggctaccgcg agtacggcag cgacgcggtc gtgaccgtga cgcagatcag
     9541 aaggctcctc gaagcggggc tctcgaccga ggagatcgcc ttcctgctgc cctgtgccac
     9601 cggcgcggga cccgatctcc tgccctgcga cgacgtcctg gagatgctcc gggcgcgcca
     9661 gcggggactg gacgatcaca tcgacacgct tctccgctcg cgccggacgc ttcaggagtt
     9721 catcgacgcg accgagcggc gggcgtcgcc gtacgcccgg tccggggcat gcgaggcctg
     9781 agcgcgccgg cgtcggcacg ggtgttggcg tcggccgcgg ggatgtgtgc ggggacgcgt
     9841 gcgatcgagc cagtcgcgga agcgggggaa cacccgctcc gtgtccggaa atcgcccccc
     9901 gcgcatgggc cattttggca tctacccggc aaggctttag gttaggctcg cctaagtctt
     9961 cggccggccc cccggcgtgt gccgccgccg ccgaccgctc tgttctcatc cgaaggggcc
    10021 catgtcagcg cccggcacgg cccccggacc cacccggtcg gggccgcagg cccaccggcc
    10081 acggccggcg ccgcacggga cccacccggg ccggttcgat tccccacccc ccagccgagg
    10141 ttgaaaccga cgtgtccgtc cagttcccgc catccgccgc gccgctcgtc gcccaccccg
    10201 tggacgtcct gccggccccc gtccgcagcc gactgctgga gatggcgcgg ggcgccgaac
    10261 ccgtgtcggc gtacgtgtac gacggagagg tcgccgccgc gcgcgcccgg gagctgcgcg
    10321 ccgcgctgcc cgactgggcg gccgtctact acgcggtcaa agccaactcg ttccccggca
    10381 tcgtccacgc cctcgccccg cacgtcgacg gcttcgaggt cgcctccgtc agcgaactgg
    10441 aactcgccct gacagcggcc gggttcgcgg acacgccggc cgtcgtcgcc gccgggcccg
    10501 ccaagtccgt acccgtcctc accgcgctcg tccgcgcccg cgtcgaggcg atcaacgccg
    10561 agagcctgct cgaactccac cggatcagcc gtatcgccgt cgccgaaggc gtcaccgcgc
    10621 gcgtcgcgct gcgcgtcaat ccggccggca tcccgatcag cggctcgctc cacatgggcg
    10681 gcgcgccctc gcagttcggg gtcgccgagc ccgacgtgcc ggacgtcctg gccgccgcgg
    10741 gcaagctccc cggcctcgac atcgtcggct tccacatcca cgccgcgtcc aacaacctcg
    10801 acgcggacac ccatgcggcg tacctgcgtt ggtgcgtcga gtggagcgtc cgcacggccg
    10861 ccgccaccgg catcgagctg cggcacatcg acatcggcgg cggcataggc gtggcgttcg
    10921 agggcgaggc gcccttcgac atggcccgct tcggtgaact cacggcgctc gtcgagccac
    10981 ccgtaggggt gaaggtcgtg ctggagcccg gccggttcct ggtggcggac tgcggctggt
    11041 acgccgccga ggtgaccgac gtcaaagcct cgttcggcga gtggttcgcc gtactgcgtg
    11101 gcggaatcaa ccacttccaa ctgcccacct cctgggacat cgtgcacaac gtcgccgtgc
    11161 tgcccgtcga cgcgtgggag gcgggtgagg ggtgtccgag gcccgccgcc gaacacacgc
    11221 gtgtcaccgt cgtgggcgag ctgtgcacgc ccgaggacac cctgctgcgc gacgtgtacg
    11281 tcgagcgggt gcgcgccggt gatctcgtcg tcttccccaa cgcgggctcc tacggctggg
    11341 agttcgccat gcacgccttc ctcggccacc cggtcgccgg gcgccagctg ctctgagccg
    11401 tctcctccac ctcatactcc ggagccgatc catgaccgtt cccgctgcca cgctgtccgc
    11461 ctccgggtat cccgccggtg acccggacac cggcgacgcc ggcgcccccg gtgacgccca
    11521 ctccatcctg gagcggcagc gcgccaggga gtcgtccgcg cgcacgtacg cccgcagctt
    11581 cccgatcgtc ccggcccgcg cccacgggat gacgatcgag ggcgtcgacg gccgccgctg
    11641 tctcgactgc ctctccggcg ccggaacgct cgcgctcggc cacaaccacc ccgtcgtgcg
    11701 cgaagccctc cggcgcacgc tcgacagcgg ggcgccactg catgtgctcg acctcgcgac
    11761 accggagaag gacgacttca ccgacgcgct gttcgagacg ctgccgaagg cgttcgccga
    11821 ccgcgcccgc gtccacttct gcgggcccgc cgggacggac gccgtcgagg ccgcgctgaa
    11881 gctgacccag acggcgaccg ggcggcgcgg agtgctcgcg ttcaccggca cgttccgggg
    11941 caacacgctg gcgatggcga cgggcgcggc gacgctccgg tacgtcacgc gcgaagggct
    12001 ggcggagcgg tcggcgacgg tcggcgcgcg gatgtcggcg cggctcgacg ggctgcggtc
    12061 cgaactgccg ctgatcggcg acgtacgggg gcgcgggctg atgatcggcg tcgagatcat
    12121 cgaccccgag gggccgtcgg actcctgcgg ggcccggccg gtggcgcccg gactggcggc
    12181 gcgggttcag gaaggctgcc tgaagcgggg gctgatcctg gaactgggcg ggcggttcgg
    12241 gtcggcggtg cggctgctgc cgccgctggt gatcacggac gaggaggccg agtcggtgcc
    12301 ggagcggctg acggaggcga tcgccgaggt ggcgaaggcg ccggggaaac cgaagccgtc
    12361 gaaggcaccg gagtccgtgg acggtgccgg ggccgtgggt gtttccgggc gggcggcgtg
    12421 accacggagg cgctgggcgc cgccgtcgag gacgtactgc gagcactccg gccggagacc
    12481 gggaccgagt tgtcgggcgg ggtgggcgga gccgccgcgc tggagccgct ggtacgtgac
    12541 gtgctgggtg cgctcgcggc gggcgcggca cggcgcggcg ggccggtcgc ggccggtgcg
    12601 ccggccggga tcgaggcggc cgtcgccgag gtgttccgca ccgcgggcgg tcccagggcg
    12661 ctcggcgagc tcaccgaact gctgtcgtac ggcagcgcgg acccggccga ccccgcgtgc
    12721 gcggcgcatc tgcactgccc gccgctggcc gtcgccgtcg ccgccgacct ggcggtgtcc
    12781 gcactgaacc cctcccagga ctcctgggac caggcccctg cggcaactgc cctggaaaca
    12841 ctgctccttc aggagctggc ggccatgctc gggtacgacc ccgccgaggc ggcgggcgtg
    12901 ctcacctcgg ggggcaccga gtccaacctg atgggcctga tgctcgccag ggaccgggtg
    12961 ctcggcgcgg cgacgggccg gcagatcgag ctgacggggg tgtcgaggac gggcgccggg
    13021 gtcggcccgg gggcggtggc cggggcacgg ccgaggatcc tggcgtccgc cgccgcgcac
    13081 ttctcggtgc agcgggcggc ggccctgctc gggctcggcg aggactcggt catcccggtc
    13141 gccgtcgact cccaactcag catgaaatcg ggcgcgttgg cggcgaagct ggagcagtgc
    13201 gtcgaacgcg ggcagctgcc cgtcgcgatc gtcgcgaccg ccggtacgac cgacacgggc
    13261 gcgatcgacc cgctgcggga gtgcgcggag ctggcggcgg agtacggggc atggctgcac
    13321 gtggacgccg cgtacggggg cggcgcgctg ctgtccgacc ggctggcgcc actgcttgac
    13381 ggtatcgaac tggccgactc cgtctccctg gactggcaca agctgggctg gcagcccgcc
    13441 gccgccgggg tcttcctggt gcggaagtcg cagacgtacg cctcgctcgc gcgccgcgcg
    13501 gtctatctga acccggcgga cgacgaggag gcgggctatc cgagcctgct gggtctctca
    13561 ctgcggacga cgcgccgcgc ggacgccttc aagatcgcgg tgacgctgcg gacgctgggc
    13621 cgggaggggc tggggcggct ggtcgacgcg tgccacgagc tggcggtggc gggggcgcgg
    13681 gcggcggccg cgcatccgcg gctggagctg cacggcgggg gcgggccggg tggcggagat
    13741 ccggtgctga cggcgttcct gttccggtac gtgccggcgg agggcgcggc ggacggggcc
    13801 cgcaccgacc acctgaacgc ttcgctgcgc cggcggttgc tccgcgaggg cggcgcggtc
    13861 gtgggccgca cggagctgcc gggggagggg ccggggcgcg tacggctgaa gctgacactg
    13921 ctgaacccgc atgcgacggt ggcggaggtg gagcggctgc tggacgcggt ggtggccgcg
    13981 ggtgtggcgg aggaggggtt gtgagcgggg cgggtggttg gcggtgcgct gccccggacc
    14041 ccgctcctca atcgccggag gggcttgatc ggtccgccgg ggtcgatccg ctcgatctac
    14101 ccgatcccct ccgcgccgcc gactccgtcg ccgtcgagac cctgctccgt gcctacgtcc
    14161 gggagaccgg gaccgacgtg cccggcagcg gcagcctgct gtatctggcc ctgccgtgca
    14221 gtgcgctgac cctgcgcgtg cgggtgctgt accggtccgt caccgggtgg caccggttcg
    14281 ggagcgtacg tgtcgtcacc tccggcaagg gcggcagcct gcccgccgac gtggggctcg
    14341 tcgccgccgc gctcgtacgc gagtccaccc tcgggcgcgg cgcgccgccg tacctcggcg
    14401 ccgatgccgt cgggcggatc gtcaactccg ccgtgcggac cggggcgcac ctggtgcggc
    14461 ggcggggcga gacaccgggg acgcgagggg tgacgccgtt tctcgacgcc gagcaggcgt
    14521 tgctgctcgg gcaccccttc caccccgcgc ccaagagccg cgagggcgca tccgacagcg
    14581 aactcgacgc gtactcaccg gagttgagag gatccttccc gctgcactgg tttgccgtgc
    14641 acccggacgt cctcgtgggc gagagcgcgg acgggcgcac ccccgccgag ttgctgcgcc
    14701 ccctcaccga cgggctcggg ctgtccgtac ccgacgggat gaccgtggtg cccgcgcatc
    14761 cgtggcaggc gcgggacgtg ctcgcgaggc ccgccgtccg cccgctcgtg gacgcggggc
    14821 tgctgcggcc gctggggccc gccgggcccc actggtaccc gacctcgtcc gtgcggaccg
    14881 tgcaccggcc cgacgccggc gtcatgctga agctctccct cggtatgcgg atcaccaact
    14941 cccgccgcaa caacctgcgc ggcgagatgc ggctcggtgt ccgcgcggcc cggctgctgg
    15001 ccgccgggcc cgccggacgg ctgcgggccg agcatccgga gttcgggatc ctgcgcgact
    15061 ccgggtgggt gtcggccggt gtggacggcg acgccgagac ggggctggag accgccgtac
    15121 gcgacaaccc gttccggggc ggcgcaggcg acgggctctg cgtcgccggg ctggtggccg
    15181 agcggaccgg gcccggcgac ggctcgccgc ccgcgcaccg cgcgctgctc tccgaggccg
    15241 tcgcccgtac cgcccgcgcc cacggtgtct ccaccgcgga ggcgtccgcg cgctggctgg
    15301 ccgcgtacct ggacgtgctc gccgttccgc tcatccgtct ccgcgcctgg tacggcatcg
    15361 cgctggagcc gcaccaccag aacacactgg tcgcgctcgg cgcggacgga ctgccgcgcg
    15421 ccggctggta ccgcgacagc cagggttact acgtcgccgc gtcccacgcg gccgacacgg
    15481 agcggctgtt gccgggcgcg gccgacgggc tcgaccttgt cttcgacgac gcgttcgtgg
    15541 acgagcgcgt cgcgtactac ctcggcatca acaacctcct cggcctcgtc ggcgcgttcg
    15601 gcgccctcgg gctggccgac gagggcgacc tgctgcgcgt gctgcgtgcc cggctggagc
    15661 ggctgcgggc cgcggagccc ggcgcgaagg cactgctcga cctgctgctg gacgcgcccg
    15721 tgctgcgctg caagggcaac tacctgacct gcgtggacgg gctcgacgag ctcgtcgggg
    15781 acgtcgagtc ccagtccgtc tacgtcgacc tgaccaaccc cctcgcggag gcccagcggt
    15841 gaccgagtcc gagcccgagt ccgaatcgag tacccctgtg tacgacctgg tcggcgtcgg
    15901 catcggtccg ttcaacctct ccctcgccgc cctggcggac ggtgccccgg agctgcgcac
    15961 gctgttcctc gacgcgaagc ccgcgttctc ctggcacccc ggtctgctga tggagggcac
    16021 caccctccaa gtccccttcc tggcggacct cgtgacgatg gtcgatccga cgagcccctg
    16081 gtcctacctc aattatctgc gccaccacga ccggatgttc cccttcttct tctcggagcg
    16141 cttccacata ccgcgccgcg agtacgacgc ctactgccgc tgggtcacgg aggggctggc
    16201 gtcctgtcag ttcgacgccc acgtggaccg gttggggtgg gacgagcggc gggagctgtt
    16261 cgtcgtcgcc caccgcacgg cggacggcgc cctcacccgc gtcctcgccc ggcaggtcgt
    16321 cctcggggtg gggacgaacc cggtcgtgcc ggagccgctg cgcccgctgc tcgcggacag
    16381 cgcgcacacg ggccgtgtcc tgcacagcgc cgactaccgg acgcaccgcg cacggctcgc
    16441 cgcctgcgac gacgtgaccg tcgtcggcgc cggccagtcg ggcgccgagg tcgcgctgga
    16501 cctgctgcgg caccaggacg gggcgggggc gggcggcccg tacgtccgct ggctcgcccg
    16561 cacgaacgcg ttcgcgccga tggagtactc caagatcggg ctcgaacact tcacaccgga
    16621 ctacatccgc tacttccgcg ccctcccgga ggaccggcgg gagcagctcg tacgggaaca
    16681 gtggcagctc tacaagggcg tcagcgacga gacgctgggc gagctgcacg acgagatgta
    16741 cgagcggacg atcggcggga cggacccgag ggccgcgctg catcccggag tcgagatcgt
    16801 cgcgaccgaa gtggcgggcg gcgactacgt gttgacgtgc cgtcacgcgc agcaggacgc
    16861 gctcttcgag atccggacgt ccgcgatcgt ctcggccacc gggtacgcgg ccacccggcc
    16921 cgccttcctc gacggcgagg agggcgaggg cggcgaaggc ggcgagcggg gtctcggcac
    16981 gctcgtggac tgggacgcac agggcaggta ccggatcgac ggcgagtacc gcgtcgcgct
    17041 cgaccccgga gtgtcgggca cgctgtacgt ccagaacgcg gagatgcaca cgcacggcgt
    17101 cggcgcgccc gacctgaccc tcggcgcctg gcgcgcggcg acgatcctga acgccgtggc
    17161 cgggcggacg gtgctgcggg tcccggagcg ggcggcgtgg acgacgttcg gggtgccgcg
    17221 ccccggctcc ggcacggacc gcgcccaccc ccacctcccc gcgcccgcct ccgcccattc
    17281 cgccgtccac gaggagaacg tccgatgaac caactcgacc gggacgcctg ggagcaggcc
    17341 ggccgacggc tgctgatcaa ggccgtcgag gagttcgcgt acgaggaact gctcgtcccc
    17401 ctacccgacg ccgggaccgc cggccagtac cggctcgacc tcggcgacga cgtgcactgg
    17461 acgctgcgcg ccgctcgcgg caccttcggg acctggcgtg tcgagcccgg cagtctgctc
    17521 cgccacccgg acgtcggcga cggccgggag gccggccccg agcgcctgct gctcgacgcg
    17581 cgcggtgtcc tcggctggga cggtgtcacc accgccgagg tcctgcgtga gctgaccgcc
    17641 acccggcggg ccgacgccga ggcgatcacc agggcgctgc ccgccgccga gctggccgat
    17701 ctggaccatc tggagctgga ggcgtaccag gacgggcatc cctgcatgct cctcaacaag
    17761 ggccgtctcg gtttcgccgc ctccgacgcc gccgcctacg cgcccgaatc cgcccccgcc
    17821 gtacggctgt tgtgggccgc cgtgcacagc gacctcgcca cgtactccgg cgtccccggg
    17881 ctcgacgcgg agcggctgct cgccgaggag ctggacccgg cgacgcggga gcggttcgcg
    17941 gccgtcctcg ccgaggagtg cgcccggaac ggcctgagcg gcgaggagtt cagctggctg
    18001 ccggtgcacc ccttccactg ggacgaggcc gtcgccaccc tcttcgcgcc ctatctcgcc
    18061 gagggccgca tcgtggcgct cgggcagagc gacgaccgct accgtcccct ccagtcgatc
    18121 cgcaccctcg ccaacatcga ccacccgcac cgccgcaacg tcaaggttcc cctcctcatc
    18181 cgcaacaccc ttgtctggcg ggggctttcg accgagccga ccgaggccgc gcccgacgtg
    18241 agcgcctggc tgcactccgt acgggacgcc gacccgtatc tgagccagga gctgcgcatc
    18301 catccgctcg gcgaggtcgc ggccgtcgcc gtggggcatc cgctctacga gtcggtcaag
    18361 gacgccccgt accgctacca cgaactcctg ggcgccgtct ggcgcgagcc agtggccgcg
    18421 ctgctcgaca cggacgcggg ggaacgcgcc cgcaccatgg ccgcgttgct caagaccggc
    18481 tccgacgggc gcgcgctcac cgccgagctg gtcgagcgct ccgggctcgg acccacggcc
    18541 tggctggaac gattcttcgg ggcgctgctg ccggggctgc tgcactacct ctaccgctac
    18601 ggcgtcgcct tctgcccgca cggcgagaac accgtcgtcc tcttcgaccg cgacgagatc
    18661 ccggtcggta ccgcggtcaa ggacttcgcc gaggacgtga acctgctgcc cggcgcccgg
    18721 ccggagtacg ccacgctctc cgagcgcgcc gaccgcgtcc tgctgcgctg gccggcccac
    18781 gagctggcgc actcgctgct cagcgcggtc ttcgccgggc acttccggtt cttcgccccg
    18841 ctgtgctccg cccaactcgg cgtgcccgag gacgagttct gggcactcgt ccgcgccgag
    18901 atcgagcgct accacgcccg gttcccggag ctggccgacc gcttcgactc gtacgggctc
    18961 ctcgccccgt ccttcgaccg cgtcgcgctg aaccgtgaac agctcctggg cggcggcttc
    19021 cacgaccgct cggagcgcga cgagggcttc gacgtcgtgc acggcaccgt gccgaacccg
    19081 ctggcagccg caccggcacg aacaggggag cggatatgac cggggaacgc ccttcaccgt
    19141 acgagcggct gcgcgccgac gccgccgcgg ggcgggtcga ggaggtgatc gtcgccgtcc
    19201 ccgacatcca ggggcggctc cagggcagcc ggctctccgt cccgtacttc ctcgacgaga
    19261 tcgacggcgc gggcgagagc ggcggggacg gtgacggtga cagcgacggc tttggcgcgt
    19321 gcgtctatct cctcgcctcc gacgtggaga tggacacccg ccccggctac gccatcgacg
    19381 cctggcggac cggcttcggc gacttcctcc tccgccccga ccccgccacc ctgcgcaccc
    19441 acctgccctg ggacgagggc acggcgctcg tcatcgccga cgcgcactgg ccgggcgccg
    19501 ggggctcacc ggtcgccgtc gccccccgcc acgtcctgcg cacacagctc gaccgactcg
    19561 ccgagcgcgg gctgaccgcg ctcgccggta cggaactcga attcctcgtc ttcctcgaca
    19621 cctaccgtgc cgcccgcgag acccgctacc agggcctgac gtccgggacc gcgtacaacg
    19681 tcgactactc gctccagggc ctgtccggca tcgagcccgt cgtgcgccgg atccgccgag
    19741 agatgggccg ggccgggctc gcgatggaga cggcgcgcgg cgagtgccac gcggggcagt
    19801 acgagatcgt cttccgctac gcggaggcga tgacgacctg cgacaaccat gtcttcttca
    19861 agaacggtgc caagcagatc gccgcccagg agggcgtggc gctcacgttc atgcccaagt
    19921 tcgacgaggg cgagggcaat tcgtgccaca tccatctgtc gctgcgcggc gaggacggca
    19981 cagccgtcct cgccgacgcg tccgccgacg acggcatgtc cgccctgatg cggcacttcg
    20041 tcgccggtca gctcgcctgt ctgccggact tcgccctgct gatggcgccg aacatcaact
    20101 cctacaagcg actacagccc ggagccttcg cgccgaccgg catcacctgg ggccgggaca
    20161 acaggacgtg cccgatacgg gtggtgggga ccgggtcctc gatgcgcatc gagcaccggg
    20221 tgccgggcgg ggacgccaac ccgtatctgg cggtcgccgc ggcggtcgcc gccggtctgt
    20281 acgggatcga gcaccggctc gaactcccgc ccccgcaccg ggagaacgcg ctcgccgatc
    20341 cgtcggtgcc ccggctgccc ggcacgctca cggaggcgct gcaccgctgg gagagcagcg
    20401 ggatcgccgc gaaggtcttc ggtgagccgg tcgtcgcgca ctacgcgcag gcggcccgta
    20461 ccgaactggc cgcgttcgag acgtcggtga cggactggga gcggatgcgc ggcttcgagc
    20521 ggctgtagcc gccggaaggc cgggccggcg gcgaagccgg cccggcccgt caacagctcg
    20581 ggcgacagga gacctagggc ctgtcgttcg gatcttgccg ggctcgcggt ccccggcacg
    20641 cacgcccgcc gcgttgtcgt cggtcgccaa cgctccgcgt tgtctccctc ctcagccttg
    20701 cggtcgcacg caccagaccc cgctccctga tccggcctga tccaaacgac aggccctagc
    20761 cggcggcggc gccgtagttc ttctcgatct cgtccagcac cttgcccgcg ccggtgtaac
    20821 cgatgcccag catccacacg ttgtcgtcga ccttgaacac cttcccggac ttcaccgcgt
    20881 ccaggttctt ccagagcggg ccgccgatga tgtcggtctc gttggccttc ttcgcgtcac
    20941 cgtaggtgga gtagaagacg acgtccgcgt tcgcctcgtc catcttctcc gggctgacgt
    21001 cgagcgagaa gccggtcttg tcctggttgg ccgggcggcc gacgccgagg tcgccgtaga
    21061 tcgagccgac gaacgtgtcg ttgaggtaga gacgcgtgtc ggcgccctcc acgaagcgga
    21121 cgaagccgaa cgtggtcttc ttcgccgcct ccgggccgcc gaacgtcgtg gtcagctcct
    21181 tgacccgggt gtcgtaggcg tcggcgatcg tcctggcctc cgccgtcttg ccgagggcgt
    21241 cggcgtgcag ctcgaagttc tcacgccagt tggggcccgt ggtgtcggag aagaccgtcg
    21301 gggcgatctc cgacagcggc ttgtagttct tctcgtcgcg gaccttgctg ctcaggatca
    21361 ggtcgggctt cagggcggcg atcgcttcga ggttcggctc ggcgatcagc ccgaccgact
    21421 tgatgtcccc cagcttctcc tgcggcagat aggtggagaa cggcgtgtcc gcgacggccg
    21481 tcgtggcacc gaccggagtg atcccgagcg tgatcgcgga gtcgagcgcg tccgtgtcga
    21541 ggacgaccac acgcttgggg tcccgcggta ccttcacctc gcccatggcg gtcgtgacgg
    21601 tgtgcgtccc tcccggcgcg gccttgtccg aggactcgtc gccgtcgcca ccgcacgcgg
    21661 agagtgagac ggcgagcgcg gtggccgcgg cggccacgcc gatacggcgg gtgaggtgtg
    21721 tggacacggt gggcaagcct cctgacgacc gcccggagtc ggcccggacg taactaaggc
    21781 aaacctaact atagcgggac cggcccaaca agttccgtac atcacggtcc agtcacaggg
    21841 cccgccgccg gcgccggagc ccgctccgaa ggagtagggc gggctcgcac gtaccatcga
    21901 cgggtatccg accccccgga cgaccggccg gcccgacgat ccggaccacg agccgcgacg
    21961 gcgcacggac cgaccggccc cgcctggggc acccaactcg acctgggcga acgggccgcg
    22021 ggccccctgc acctgcggct cgttcgggcc ctccgggcgg ccgtcgtgga cggccgtatc
    22081 gctcccggca gcgctctgcc gcccagccgg gcgctcgccg ccgatctcgg ctgctcccgc
    22141 tgggtgcgtg tgcgtgtccg tgttcctcgg gtcacgctgg gcgccggtcg gcacggtgta
    22201 ccggtccgat ccacggatga aaaaccactc cgattcgcgg cttgggagcc aatcccgctc
    22261 cgcacgcgtc cccagaggca agacggctga atacccccac agttcgagga gagacgagcg
    22321 tcatggactt cgccacgaat acgccgacga acacaccggt cgagaccacg ctgggcgagc
    22381 agctgctcct cctctcgctg gacgacgagt ccggggccga gaaggagtcg atgaacgtct
    22441 cctacgccat cgcggcggcg tcactggtcg aactggtgct ggcgggccgt gtcgaggtga
    22501 acgaggacca ggtcaccgtc cgcgacgcgg cgcccctgga cgaccccacc ctggacgtgg
    22561 cgctggccga catctccggc gaggacaagc gcaagccgcg caagacgaag gagtggatcg
    22621 agcacctgaa gaagggcgcg gtggccggga cgaccgggaa cctcgtggca aaggggctga
    22681 tccgcgagga gaagaagaag gtgctcggac tcttccccgt gcgccgctac ccggaggccg
    22741 acggctcggt ggagtcggcg ctgcggcagc ggctcgacga ggtcgtgatg cgcggggcgg
    22801 ctccggacga gcgcacggcg agtctggtgg ccctgctgca cggggcgaag ttgcacggac
    22861 tgctttacga gaagccgcag ttggcgaccg ccaaggtgaa catggagaag gtcgcgcacg
    22921 gccagtgggc ggggccggcg gtgcgccagg cggtcaaggc ggccgaggac gcgctgacgg
    22981 cgatcgtcct gctgacggtc gtcacgacga ccgtcctgtg accggccgag gcggcctcac
    23041 cagccctctc accagccggt gaagacgagg tggttgacca gcagggcgac ggccgcctgc
    23101 ccggccagcc accatcgccg gcggcccgga agcagggcgg tggcggggat cagccacagc
    23161 atgaacggca gccagatgcg ttccgtctcc gccttgctca tcccggacac atccgcggcg
    23221 acgatcgcga gcgccgccgc caggacgaga acggccaggc gaagcgtggg agttgaggcc
    23281 gctcgggcgg gtcggaccct ccgtacggcg cggggcgcga gcacgaagac gcggcccaga
    23341 ccggccgccg tcgcgaggcc gacggccagg gtggtggcgg cgaggttccc ccagatccag
    23401 taccagtacg ggcgcacccc gcccgcgccc tggtagtagc gcacgaccaa ctcgtggtac
    23461 gcctcccacc agttgaaccc cgcgagcgtg aacgccaccg gcacgaccag ggcgcccgcc
    23521 agcaccaggg gcagcggacg cgcggtgcgg gccaggacga ggatccccag gccggggagc
    23581 gccatgagcg tcaggccgta cgagagatag cacgtccatc cgtacagcag cccggcgccc
    23641 agcgcggcgg cggccgggaa gcgcgccgta cgcgtcgcgg cgagcgcgag cagggcgagc
    23701 gaccaggcgg cgacgcccgc gaagtagccg tcggccgacg tgcccaccca gacggcggcc
    23761 ggggccagcg ccaggaaggg cgccgcgcgg cgcgcggtgc gctcgtcggt cagcgcgcgg
    23821 agcgtgacga gtacggcggc cacggccgag ccgcccacca cgatgcacca gaccccggcc
    23881 cacgagccgc cgccgaggcc gatccggtcg agccagacga aggtgagggt ggcgcccggc
    23941 ggatgaccgg cgacatgggc gggccagttg ccgggcgggc cgatcacgat gtggtcgctg
    24001 aagccgcgca gcgtcgcgcc gatgtcggag aagcggtcga tgacggtgag gtactcgttc
    24061 ttggtggtga gccggcgcgc cacgccccag tgccacccgt cgacgagcgc cagcgagaac
    24121 gtccaggcca gcgcggcgga ccaggtggtg aggaggagcg cgcgccacgg cagccgggcg
    24181 gcgagaccgg ggccgtacgc gacgatcagg acggcgacgg cgagcgcggc gggggtgccg
    24241 gggccgacgc gggggtccca ggtgcccagc agcggcggcc agttgacctg gaggctgccc
    24301 tcggcgcgct ggatcgcccc gccgacgagc gcggccgtgg tgacgagcgc gaggccgacg
    24361 ccggcggcga cgagatcccg gcggtgcggg cggccggtgc gttcgtgtcc gtggacgtcc
    24421 gcgtcttcgg ccgcgtccgc gtccgggtgc gcgccggtgg gtgtgtccgt gcccgtgtcg
    24481 ccgagtgggt gtcctcgttc atctgtcttc accccggcac gttatgcagc gggtggcgcg
    24541 ttccggcggt acggcggcgc cacgtcacca tttcgtcaga agtcgtaccg cctcccgggc
    24601 gggtgcgcgg gtttacggtc gcggtatgga ccacccccca cggctgtcga agcgccccgt
    24661 cggcgcactg ccaccgctgc cgaccgaccc caccttctgg cgcagtccgg tgcgcggtgt
    24721 ccggttcacg gcggtgctcg gactcgtact gctggccgga ctcaccctgc tgttcgtgac
    24781 gggtctgctg tcgtacgcgg cgtacaaccc ggatctcgcg tccgtcaacg acaagacccc
    24841 ggaccgcgga tggctcggct tctacctctt cgactggccg acccacccgt actggctcta
    24901 ccgcctcatc caggggctgc acgtcacggt gggcatcgcg ctgatcccgg tgctgctggc
    24961 gaagctctgg tcggtgatcc cgaggctgtt cacgctgccg ccggtcacgt cgctcgcgca
    25021 cgcgctggag cggatctcgc tggtgctgct ggtgggcggc gcgctgttcg agttcgtcac
    25081 aggcgtgctc aacatccagt tggactacct gttccccggg tccttctacc ggctgcactt
    25141 ctacggggcg tgggtgttct tcggggcgtt cgtcgcgcac gccgcgctga agatgcccaa
    25201 ggcgctgcgg gccatccgga gcggggagct ccgctccggg agaaccggcg gcggtacggg
    25261 ggccggggcg caccgcgccg cggggacgga ggacgacctg gcgtccccgg cgcccgcgcc
    25321 gccgaccctc tcacggcgcg gcgcattcgc cgtcgtcggc acgggatcgc tgttcatgct
    25381 gctcacgacg gcgggccgga gtttcgacgg tccgctgcgc cgtaccgcgc tgctcgcccc
    25441 gcacggctgg caggacccgg gaggcggccc gaacggcttc cagatcaaca agacggcggc
    25501 ggcggtcggg gtcagggcgg ccgacaccgc cggggaccgg tggcggctgg tcgtcagcgg
    25561 cccggccggg gacgtacggc tctcgcgcgc gcagctcctc gcgatggacc agcacacctc
    25621 cgagctgccg atcgcctgtg tggagggctg gtcgacgtcg aaccagtcgt ggcgcggcgt
    25681 acgcctgcgg gacctcgccg cactggccgg gtatccggcc gacgcgcccg gtgtgttcgt
    25741 ggagtccctc caggcccgcg ggagtttccg ttcgggcgcg ctgcgcgaca accaggtgcg
    25801 cgacgggcgt tcgctgctgg cgctccgggt caacggcgcg gacctgtcgc tcgaccacgg
    25861 cttcccggcg cggatcatcg tcccggccgc gcccggggtg ctgaacacga agtgggtcac
    25921 caggctgacg ttcggagcgc tgtgatgaat cgccggaacc gtacggggcg cgccatcgag
    25981 cgccgcgtcc tcaaggaccg ctccctccaa taccgctcgc tgctgggcag tcccctccag
    26041 atcgtgctgc tgctcgccac cctcgccttc gtgggatatg tgggagtgcg cctgctggtg
    26101 ggcgagacgt tcctgatcgt ggtctggttc gtcggcgccg cgctcgtgca cgacctcgtc
    26161 ctggtgccgc tctacacggc ggccgaccgg acggtgaccg ccgcgctggg accacggcgc
    26221 cggctcgtca actacgtacg tgtaccggcc ttcctgtcgg ggctgctcct gctggtgtgg
    26281 ttcccgatga tcacggggcg ggtgaggcgc tacgagccgt acgccgccct gtcgcccgac
    26341 gggttcctgg cgcgctggct gctggtcacg gccgcgctgt tcgtgtgctc ggcgctctgt
    26401 ctggtgacgc gcgcggtact gcggcgcagg gcgacgaagg ggcggcccgc cgcctcccac
    26461 tgatcgacgg gctgccagcc gatggcccgg ccgtaccgga gcagcgccgg ggtgccgagc
    26521 cgggcccacg ggaagtgcga gcccgtggcg cgggctccgt ccgccggggg gtggcgcccg
    26581 tcgtccaccc gtacgcgcac ccgctcgtcg atgtccacgg gcgcggtctc ggcgatgatc
    26641 agcccgccgt gcctcagcag tccggcggcc cggcggagca gtcctgccgg gtccccgccg
    26701 ataccgatgt tgccgtccac gagcaggacg gtgccccaac gtccctcgcc gggaaggggg
    26761 tcgaagacgg agcggtgcag ggcggtgccg ccgagccgca gcgtgcgttc gacggcagcc
    26821 tcgctgacat cgacgccgag cgcctgccgc ccgcgcgccg cgagcgcggc gacgaggcgg
    26881 ccggggccgc agccgatgtc caggacggcg ccctcgcagc ggtgcagggc cgagaggtcg
    26941 gcggcgtcgg cgcgggcgca ccagcgctcg acgtccaggg gcagcagcca gccgtccgta
    27001 cggcgcagga agagcgggcc gcggccggcc cggagggcgt cggcgtacgg gtcggtgctc
    27061 caggcggcgg cctcggtgcc ggtgtccgct gtgccggtcg ccggggcgtc ggtgccggtg
    27121 tccgtggtgc tcaccgggcg cccaccgggg tgagccggcg cagggtggcg gcgaactgcc
    27181 cgtccggggc cgccgatgcg acgtactcgg cgtcggccgc cgagtccacg tcgcgcagcg
    27241 gcggcagatc gcgcacggtg aacccggcgc ggacgagacg gcggcgctgg acggcgccgg
    27301 tgtcgggtgc ggacatgggc accccgcgaa tgaggtccgg cggggcggac tcgggggcgg
    27361 cgaggcccag cgcccagaag ccgccgtcgt cggcgggtcc gaaccaggcg tcgcagccgt
    27421 cccagccggc cggaccgagc gcgggggcca gcaggtcggg ggtgatctgc ggggtgtcca
    27481 tgccgacgag gagcgtcggc cccttacagc tttcgaaggc ggcggccagc cgctcgtcga
    27541 gcccgcccgc gcactgcggc accacgtcga tgccgggtgg cagccagggt cccgggcgtc
    27601 cttcgaggac caggacacgg cgccgggcgg ggagggcgcg gacggtccgc agggtgtcgg
    27661 cgagcgcggc ctcggcgagg cgggcggcgt cggcgggggg gaagggcggg gtgaggcgcg
    27721 tcttgacgcg gccggggagg ggttccttgg cgatgacgag cagggtggtg gtgggggagg
    27781 tcacttggcg gcctccgcgg gagcgttcgg gacggtgttc ggcgcggtgc tcgtgcgccg
    27841 tagggactgc gcggggggcc ggctcagcac ggcgcgcatg tcgcgtaccg cgtgccaggt
    27901 gccccgccag gtgccggtga ccttggacct gcccgtacgc ggtcggtagg gcacgtcggc
    27961 ctcgttgacc ctcagtccgg cgtcggccgc gcgcaccacc atctccagcg ggtagccact
    28021 gcgctggtcg gtgatgccca gcgccagcag gtccgcgcgg cgcgcggcac gcagcgggcc
    28081 gaggtcgcgc agcgtcacgc cggtgcggcg gcgcagcatc cgggagaggg cgagattccc
    28141 ggcgcgggcg tgcgcgggcc aggtaccgcg gccctgcggg cgacggcggc ccagcatcaa
    28201 gtcggtctct ccgagggcga cttggcgtac gaagccggtg aggagaccgg ggtcgaggga
    28261 ggcgtcgcag tcgcagaagc agacgtactc ggcgtcggac gcgaggaggc ccgcgtggca
    28321 ggccgcaccg aacccccgtc gcggctcgtg gacgacggtg gcgccgaacg agcgtgcgac
    28381 gtccgccgag ccgtccgtgg agccgttgtc gacgacgatc gcgcgccagc cgacggggat
    28441 gtgttccagc acccatggca gcgcggccgc ctcgtcgagg cagggcagaa caacatcggc
    28501 ggtaagatca gagaggttgg tcacggcgct caccctacgg atcgtaaggc cgcataacgg
    28561 acttctggac cttacgaaac acggacgttc ggccgatccg ggcgctcggg cggtctctcg
    28621 cgcggggcgc ggtgcgaagg tggacgtatg cagagcaatc ccatcggcgg cgacgccggc
    28681 cacggcgcga acgggcaggc acccgcccat gtcctcgtcg tcgacgacga tccgaccgtc
    28741 gccgaggtcg tcgccggcta cctcgaccgg gccggtcacg acgtcgcacg cgccgccgac
    28801 ggcccgtccg cgctcgcgcg attcgcccgc agacggcccg acttggtcgt gctcgacctg
    28861 atgctgcccg gcatggacgg cttcgaggtc tgccgccgga tgcgcgaaca gggcggcccg
    28921 gtaccggtga tcatgctgac ggcgcgcggg gacgaggagg accgcgtact ggggctggag
    28981 acgggcgcgg acgactacgt caccaagccc ttcagcccgc gggagttggt gctgcgcgtc
    29041 gggtcggtgc tgcgccgggc gcggctgccg gtgcccgtgc ccggtacgtc gccggcggcg
    29101 ggcgtgctgc gtacggcggc cctctccctg gaccccgcgg cgcggcgcgc cacccgcgag
    29161 ggcgccgaac tggcgctcac cctccgggag ttcgacctgc tggccttctt cctgcggcac
    29221 ccggggcggg cgttctcgcg cgaggagctg atgagcgagg tctggggctg ggacttcgga
    29281 gacctgtcga cggtcacggt ccatgtccgc cgcctgcgcg ccaagatcga acacgacccg
    29341 gcgcggccgc ggttgatcca gacggtgtgg ggggtcggtt accgcttggc ggagccggag
    29401 gacatggctg cgggcgggag cgcgggtgcg ggcgccgggc gtccgccgca ggacacccgg
    29461 cccgcacccg gcgcggaagg cgtcccggac atcccggccg gcgcctcggc gtcctcgccg
    29521 gacacgccgc cccggtcacc ggacacgccg ccccggtcac cggacccgtc acccggctcg
    29581 gacccgtcac ccggctcccg gaggtccgcc cggccatgaa ggacatgctc ctcatcgctc
    29641 tcatcgcgtt tctcggcgcc gcggccgcgg gcctcctcgg ggccctcacg ctgcgcctgt
    29701 tccggcgccg gtcgctcgtg gtgtccgtga ccgtcgtcgc cgccgtcgcc gtgaccgcga
    29761 tgctcgccgg gacgctcgcc gtcgcctggg cgatgttcct gtcaccgcac gatctgagcg
    29821 tcgtcaccac ggtcgtcgcg atggccgccg tcgtctcgct cgtcaccgcc gtcctcctcg
    29881 gcagatggat ggtcgcccgc agcagggatc tgaccctggc cgccaggtcg ttcggcgacg
    29941 gcggggtctt cgccgcgccc gtcgagcccg cgaccgccga actggacgcg ctgacacgcg
    30001 agctggcggc cacgagtgcc aagctcgaca gctcgcgtga gcgtgaacgc gcgctggaga
    30061 cctcgcggcg cgaactcgtc gcgtggatct cgcacgatct gcgcacgccc ctcgccgggc
    30121 tgcgcgccat gtcggaggcg ctggaggacg gcatggccgc cgactccccg cgctatctgc
    30181 ggcagatacg taccgaggtc gagcgcatga acgacatggt cggcgatctc ttcgaactct
    30241 cccggatcca cgcgggatcg ctcaccctga cccccacccg tatctcggtg tacgacctgg
    30301 tcggcgacgc cctggccggc gccgatccgc tggcgcgcga gctgggcgta cggctcgtgg
    30361 gcgaccggat cgacgccgta ccggtggagg tcgacagcaa ggagatgagc cgggtcctcg
    30421 gcaatctgct gatcaacgcc atccgccgga ccccggccga cggcacggtc gcggtcgccg
    30481 cgcggcacgg tcagggcggg gtggtgctct cggtgaccga cggctgcggc ggaataccgg
    30541 aggaggacct gccgcgcgtc ttcgacacgg gctggcgcgg cagcgacgcc cgcacacccc
    30601 cggccggcgc gggcctcgga ctcgcgatcg tacgaggcat cgtggaggcc cacgcgggcc
    30661 gggcggcggt ccgcaacgtg gcgggaggct gctgcttcga ggtgacgctc cccgccgcct
    30721 gatccgagcc gcgccatacg gagcggggag cgcgtcacgg ccgggcgcgc cccgccgccc
    30781 ggacacgccc ggcgcccccg gtcaccgcgc cctgcggcga gcgctccgta cggttcgtcc
    30841 atgactcccc ccggttcacc ttctcgcccg gccctcggct tccacgaact gcaccaccgc
    30901 accgcgccct tggtcctccc caacgcctgg gacgtcccct cggccctcgc cttcgtcgac
    30961 gccgggttcg aggccgtcgg cacgacgagc ttcggtgtcg cctccgggct cggccgtccg
    31021 gacggcggcc ggtcgacgcg tgacgcgaac gtcgcgctgg ccagggccct ggcgccgctg
    31081 ccggtgcacg tcagcgtgga catcgaggac ggctactccg acgacccgga cgaggtcgcc
    31141 gcgtacgtct ccacgctcgc cgccgccggt gccgacgtcg cggacgtcgc gggcgtcaac
    31201 atcgaggaca gcaccgccga gacgctgatc gacccggccg cgcacgccgc gaaggtcgcg
    31261 gcggtgaagc ggcgctgccc ggaggtgttc gtcaacgccc gcgtcgacac gtactggctc
    31321 ggccaggacg ccaccgtcga ctcgacgctc gaacgcgccg cgcgttacat cgaggcgggc
    31381 gcggacggcg tgttcgtccc cggcgtcacg gagcccggcg tactgcgcga actggccgcg
    31441 gccgtcaccg tccccctcaa cgtcctcgcc gtccccgccc tctcgctcac cgaactcgcg
    31501 gggctgggcg tccgccgcgt gagcacgggg tccctgccgt accgcgccgc gctgcacgcc
    31561 gccgtgcggg tggcggacac ggtacggggt ggtggcggcg ccctacccga ggcgacgccg
    31621 tatccgcagc tacaggcgcg gctcgtcgac tacgcgtccc ggctcgcgta gcggcgcggt
    31681 cgcgaactcc gccatgccgt cggcgaagcc cacctccggc ttccagccca actcctcgcg
    31741 caacgcccgc gaatctgcgg tgacatggcg tacgtccccg agccggtact cgccggtgac
    31801 gacgggcgcg ggcccgccgt gcgccgaggc cagcgcggcg gccatctcgc cgatggtgtg
    31861 cggctcgccg ctgccggtgt tgtacgcggc gaagccggac ggcccgcccg cgcacaccgc
    31921 gtcgagggcg gccacgttgg cggcggccac gtcccgtacg tgcacgaagt cccgccgctg
    31981 accgccgtcc tcgtagacgc ggggcgcctc gccgcgcgcc agcgcggagc ggaagaagga
    32041 ggcgaccccc gcgtaggggg tgtcgcgggg catgccgggc ccgtagacgt tgtggtaccg
    32101 aagggacacc gcccgcccgc ccgtggcccg cgcccatgac gaggccaggt gctcctgcgt
    32161 gagcttggtc gtggcgtaca cgttgcgggg atcgacgggc gcgtcctccg ccaccagccc
    32221 cggcaccaac ggcgagccgc agtcggggca gttgggctcg aaccgcccgg cgtccagatc
    32281 ggcggccgcg cgtggtcccg gccggaccac gccgtggcgc gggcagtcgt agcgcccctc
    32341 gccgtagacg accatcgacc cggcgagcac cagcgccggc acacccgcgt cggccatggc
    32401 ggcgagaagc accgccgtgc cgaggtcgtt gcaccccacg tacgcgggcg cgtcggcgaa
    32461 gtccttgccg agcccgacca tcgcggcctg gtgacagacg gcctccaccc cggcgagcgc
    32521 ccccgccacg gcctcccggt cccgcacgtc cccgacgacc agccgctccc cctcccgcgt
    32581 cggccgcggt ggggccccgc cgtgcgcgga gggcagcaac gcgtcgaaca cgacggcctc
    32641 atggccgcgc gacacgaggg cgccgacgac ctccgatccg atgaacccgg ctccgccggt
    32701 gacaagtaca cgcatggggc ccacgctagg cgcgcgatca cgcagtggtc ggtacccgcc
    32761 acggcatgtc acgggaccgt aagatcacgc gcgcgtcagt cgagcggcag cacccttcga
    32821 aggagatgtt gatggagtac ttcgacctcg ggactctcac ccggcccgtg tcgacgcgtt
    32881 cggccgacgc gcagcgctgg ttcgaccgcg ggctggcgtg gacgtacgcg ttcaaccacg
    32941 aggaggccgt ccgctgcttc gaggaagcgg cgggtgccga tcccggctgc gccatggcgc
    33001 actggggcat cgcgtacgcg ctggggccca actacaacaa gccctgggaa tcgttcgacc
    33061 cgctcgacct ggagcggacc gtccgcagga cccatgccgc cgtcgaacgg gcccgcgcc
//
