LOCUS       NZ_CP048397            41203 bp    DNA     linear   CON 08-MAY-2024
DEFINITION  Streptomyces sp. S4.7 chromosome, complete genome.
ACCESSION   NZ_CP048397
VERSION     NZ_CP048397.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. S4.7
  ORGANISM  Streptomyces sp. S4.7
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7920066)
  AUTHORS   Bekiesch,P., Zehl,M., Domingo-Contreras,E., Martin,J.,
            Perez-Victoria,I., Reyes,F., Kaplan,A., Ruckert,C., Busche,T.,
            Kalinowski,J. and Zotchev,S.
  TITLE     Viennamycins: new lipopeptides produced by Streptomyces sp. S4.7
            isolated from the rhizosphere of Edelweiss (Leontopodium nivale
            subsp. alpinum)
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7920066)
  AUTHORS   Bekiesch,P., Zehl,M., Domingo-Contreras,E., Martin,J.,
            Perez-Victoria,I., Reyes,F., Kaplan,A., Ruckert,C., Busche,T.,
            Kalinowski,J. and Zotchev,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-FEB-2020) CeBiTec, Uni Bielefeld, Sequenz 1, Bielefeld
            33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8; canu v. 1.6
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 57.8x
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_010384365.1-RS_2024_05_06
            Annotation Date                   :: 05/06/2024 10:27:30
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,027
            CDSs (total)                      :: 6,939
            Genes (coding)                    :: 6,650
            CDSs (with protein)               :: 6,650
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 289
            CDSs (without protein)            :: 289
            Pseudo Genes (ambiguous residues) :: 0 of 289
            Pseudo Genes (frameshifted)       :: 103 of 289
            Pseudo Genes (incomplete)         :: 223 of 289
            Pseudo Genes (internal stop)      :: 23 of 289
            Pseudo Genes (multiple problems)  :: 52 of 289
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:05:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1057749
            Orig. end                         :: 1098952
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP048397.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Zotchev Lab, University of
            Vienna, Austria.
            Annotated using prokka v1.11 from http://www.vicbioinformatics.com.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..41203
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T3PKS"
                     /region_number="4"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     cand_cluster    1..41203
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..41203
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:21203](-)"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..21203)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     gene            complement(214..846)
                     /locus_tag="SSPS47_RS04560"
                     /old_locus_tag="SSPS47_04665"
     CDS             complement(214..846)
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006375712.1"
                     /locus_tag="SSPS47_RS04560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04665"
                     /product="GNAT family protein"
                     /protein_id="WP_164248944.1"
                     /transl_table=11
                     /translation="MSECSVTLDRIALDDWRDVHSWARLAEACRFQPWGPNTEDQTRDF
                     VKAAVEAWSHEPRQRFAHVVRFEGAVVGMGELRVRSHTYRQGEISYLVHPRVWGRGLGT
                     EVGRSLLSLGFDQLGLHRIYATCDPRNLGSSRVLAKLGMTYEGHHRHTAWIRDGWRDSL
                     MFGILEEEWEAGARSGVDPAGPVPERWGGRVRQGDFTGEAARRDGEE"
     gene            complement(980..1378)
                     /locus_tag="SSPS47_RS04565"
                     /old_locus_tag="SSPS47_04670"
     CDS             complement(980..1378)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741335.1"
                     /locus_tag="SSPS47_RS04565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04670"
                     /product="DUF302 domain-containing protein"
                     /protein_id="WP_164254380.1"
                     /transl_table=11
                     /translation="MTYSRTVHVDGDFEETVRAVREALAEQGFGILTEIDVRATLKEKL
                     GHDMENYLILGACNPPLARQAIEADRSIGLLLPCNVVVRTDGERIAVQALDPATMVTLT
                     GRDALEPVAEDATHRLDAALSTLTQQQA"
     misc_feature    complement(1457..1466)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 16.08"
                     /tool="antismash"
     misc_feature    complement(1501..1517)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 23.21"
                     /tool="antismash"
     misc_feature    complement(1502..1517)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 21.77"
                     /tool="antismash"
     gene            1541..2905
                     /locus_tag="SSPS47_RS04570"
                     /old_locus_tag="SSPS47_04675"
     CDS             1541..2905
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170: metallo-beta-lactamase family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018890928.1"
                     /locus_tag="SSPS47_RS04570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04675"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_164248946.1"
                     /transl_table=11
                     /translation="MFFVDTIELEGLGNRSYLAGGEHTAVVVDPPRDIDQVLAAAARRG
                     VRIAYVAETHIHNDYVTGGPELARITGAQYLVPAGANVSFARVAVADGDTVDIDPGSGV
                     SLAAIATPGHTPHHTSYALREGGRPVVVFTGGSLLIGTVGRPDLVEPRLTEQLARAQHA
                     SAHRLASGLPDETAVLPTHGFGSFCSSAQSEGEETTIGKEKSANTALTVDVDTFVADLL
                     AGLEDVPAYYAHMGPANAAGPAPVDLTPPALADPAEIATRLAAGEWVVDLRNRVAFAEG
                     HVAGSFNFEADGKIATYLAWMIPWGKPVTLLAESAEQLADTQRELVRVGIDRPAAAATG
                     GPAAWLPAGEKPASFPRSTFAALADRGLDHVVVLDVRRDSERADGWIEGSVHIPIHELH
                     GRLAEVPRGAVWVHCAGGMRAAIAASLLDAAGRDVVAVDDGFDAAAGAGLPLTTG"
     gene            2944..3309
                     /locus_tag="SSPS47_RS04575"
                     /old_locus_tag="SSPS47_04680"
     CDS             2944..3309
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1163: rhodanese domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017948261.1"
                     /locus_tag="SSPS47_RS04575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04680"
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="WP_164248948.1"
                     /transl_table=11
                     /translation="MSLFRRDQPRVSAERARSRTGGKAPDAIPLDVREKPEWNAGHAPG
                     AVHAPLSNLSAGADLPAGVSGTPLVVICRSGHRSQQAAELLDQRGERPVDVEGGMDAWA
                     ASGYPVSDERGNSGRIA"
     gene            3306..4049
                     /locus_tag="SSPS47_RS04580"
                     /old_locus_tag="SSPS47_04685"
     CDS             3306..4049
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018890930.1"
                     /locus_tag="SSPS47_RS04580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04685"
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="WP_164248950.1"
                     /transl_table=11
                     /translation="MTALVLALIAGAVIGLALGTLGGGGSVLTVPALIYLLDFTPPAAT
                     TASLIIVAATSVTALYAHARDGHVAWKTGSLFAAAGIVPAYLAGAASGHVPEVILTVAF
                     SLIAALAAMRMLRPSTSEPADRTRPGKATGAGAGLGAVTGFLGVGGGFLAVPALVSVLG
                     LTMRRAVGTSLLVITVNSFAALIARTGTGGGLQWEVITPFTGAAILGAWDGKRLATKIS
                     GHTLQRAFAGVLLAVAVFMLIDVIA"
     gene            complement(4071..4349)
                     /locus_tag="SSPS47_RS04585"
                     /old_locus_tag="SSPS47_04690"
     CDS             complement(4071..4349)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010358257.1"
                     /locus_tag="SSPS47_RS04585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04690"
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="WP_164254381.1"
                     /transl_table=11
                     /translation="MELEMAAGELKSVLNRLRRAQGQIAGIIKMIEDGRDCEDVITQLA
                     AVSRALDRAGFAIIATGLQHCMAEGGQAAGDRDQMRARLEKLFLSLA"
     misc_feature    complement(4366..4381)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 21.53"
                     /tool="antismash"
     gene            4435..5001
                     /locus_tag="SSPS47_RS04590"
                     /old_locus_tag="SSPS47_04695"
     CDS             4435..5001
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1163: rhodanese domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004929074.1"
                     /locus_tag="SSPS47_RS04590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04695"
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="WP_164248957.1"
                     /transl_table=11
                     /translation="MNTPTALIPAQAAARLDDYTVIDVRTPGEYASGHLPGAHNIPLAH
                     LHTALPALKAAATRGNLLMVCASGNRSTTACTQLAAADIPATTLTGGTTAWTTEGHTVH
                     RPASAQAPWPMERQVRLAAGSLVVLGLAAGTRWHPARWLSAAIGTGLVFSAATDTCGMA
                     AALAKLPHNQPRTTDLDATLRTLGN"
     gene            complement(<5172..5884)
                     /locus_tag="SSPS47_RS04595"
                     /old_locus_tag="SSPS47_04700"
                     /pseudo=""
     CDS             complement(<5172..5884)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1130: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005477235.1"
                     /locus_tag="SSPS47_RS04595"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="SSPS47_04700"
                     /product="IS256 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVAKLVERARSEGLQLTKRESALEGEITDHLGYEKHAVGGRGSGN
                     SRNGGQAKTVLTDVGPVEVKVPRDTSGTFEPQLVKKRQRRLTGVDEMVLSLSAKGLTLG
                     EIAAHLAEVYGAEVSKQTISRITDTVMEDMTEWQIRPLDRVYPVLFVDAISVKIKDGQV
                     ANRPIYVVMAVTVDGTATSSASGPATAARARSTGCMCSPS"
     misc_feature    complement(5216..5218)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    6446..6461
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.04"
                     /tool="antismash"
     misc_feature    6594..6608
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.96"
                     /tool="antismash"
     misc_feature    6677..6691
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.81"
                     /tool="antismash"
     gene            complement(7282..8331)
                     /locus_tag="SSPS47_RS04605"
                     /old_locus_tag="SSPS47_04710"
     CDS             complement(7282..8331)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012381689.1"
                     /locus_tag="SSPS47_RS04605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04710"
                     /product="sugar-binding domain-containing protein"
                     /protein_id="WP_187280310.1"
                     /transl_table=11
                     /translation="MNSSEEIAVSGMSAGRPALRMGPAELVQAAAMARRFYLEGKSKIQ
                     IAEEFGVSRFKVARVLETALERDLVRIEIRVPAELDAERSDALRARYGLRHAVVVESPA
                     EGADESPDPENLGEVAADLLGELVVEGDVLGLAWGRSTIHMAAALDRLPPCTVVQLTGV
                     YDAGTAERGSVEAVRRAAQVSGGEAHPIYAPMLLPDPATAAALRSQTGIARAFDYFDKV
                     TVAAVSIGSWEAGISTVHDMLTDEERSHYASLGVEAEMSAHLFDAEGRRVGRDLGERCI
                     TVEADRLRRIPEVVAIAGGQRKGAAIGAVLRSGLVTSLVTDTAAADFLLHDFEPGPRPA
                     LERKDPDSE"
     misc_feature    complement(8335..8349)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.57"
                     /tool="antismash"
     gene            complement(8434..9117)
                     /gene="rpe"
                     /locus_tag="SSPS47_RS04610"
                     /old_locus_tag="SSPS47_04715"
     CDS             complement(8434..9117)
                     /EC_number="5.1.3.1"
                     /GO_function="GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rpe"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044795.1"
                     /locus_tag="SSPS47_RS04610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04715"
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="WP_078078347.1"
                     /transl_table=11
                     /translation="MAQINPSILSADFARLAEEAKAAEGADWLHVDVMDNHFVPNLTLG
                     VPVVEALARATETPLDCHLMIEEPDRWAPQYVEAGAGSVTFHAEAAAAPVRLAREIRAK
                     GARASMALKPATPVEPYEDLLPELDMLLIMTVEPGFGGQAFLDIMLPKIRRTRELISKH
                     GLELWLQVDGGVSAATIERCAEAGADVFVAGSAVYGTDDPAAAVRMLRHQADEATASAG
                     WSCAH"
     misc_feature    complement(9350..9364)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 24.85"
                     /tool="antismash"
     gene            complement(9409..9699)
                     /locus_tag="SSPS47_RS04615"
                     /old_locus_tag="SSPS47_04720"
     CDS             complement(9409..9699)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023159.4"
                     /locus_tag="SSPS47_RS04615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04720"
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="WP_164248959.1"
                     /transl_table=11
                     /translation="MASTHDEPDLTELVNVGRSVARYFEGVGVTRIAQLVGEDPVELYE
                     RMSAAAGQRLDPCLLDTVMSAVDQAEGKPARPWWHYTPERRRLRSERQAPL"
     gene            complement(9699..9833)
                     /locus_tag="SSPS47_RS35935"
     CDS             complement(9699..9833)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SSPS47_RS35935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_275405138.1"
                     /transl_table=11
                     /translation="MSDSFKTRPGPRGYVAGTGTRTAACTERAEPAARTDRTREKEWS"
     gene            complement(9844..10455)
                     /locus_tag="SSPS47_RS04620"
                     /old_locus_tag="SSPS47_04725"
     CDS             complement(9844..10455)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /locus_tag="SSPS47_RS04620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04725"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_203557786.1"
                     /transl_table=11
                     /translation="MATEPDKVRKRGRPAADRAGLTADRILTTALALVDAAGLDALSMR
                     RLARELGVDPMSIYHHLPNKAAVVSGLVGLVFSRMRLPESVPDDWAGQVRAWVDAYRDL
                     TRRHPRLVLQIVTDPVAVTQASETINGPLHAALTSAGVPADKIDACAGMFVDFANGFAL
                     AGLEPPSPAPAGKPPQSHFDTGMDVMILGIRALTAGRDER"
     gene            complement(10535..11023)
                     /locus_tag="SSPS47_RS04625"
                     /old_locus_tag="SSPS47_04730"
     CDS             complement(10535..11023)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013412.4"
                     /locus_tag="SSPS47_RS04625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04730"
                     /product="pyridoxamine 5'-phosphate oxidase family protein"
                     /protein_id="WP_203557787.1"
                     /transl_table=11
                     /translation="MGETPTEREVRTMATWHEIRSGHPEFADKVSACFAAGVNKTIATL
                     RRDGSPRISAIELEFKDGDVTLGMMGGSVKLRDARRDPRVAVHSPTIDAPEGEAWHGDA
                     KLSGVLVETPAPPGNPHVGAGFFRIDIREVALTYLGTPADHLVIESWDAEHGRRRRTH"
     misc_feature    11123..11143
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 21.29"
                     /tool="antismash"
     gene            complement(11141..11716)
                     /locus_tag="SSPS47_RS04630"
                     /old_locus_tag="SSPS47_04735"
     CDS             complement(11141..11716)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607101.1"
                     /locus_tag="SSPS47_RS04630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04735"
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="WP_164248960.1"
                     /transl_table=11
                     /translation="MCAAFPDFRLGSVLATSFTGTLSERHGNAVERIPVPHRLVDWLAV
                     NGLAVDSCTTAQLDLARELRESIHAAATAAAIRDALPESAVQVINDRSAQGRAAAVLTP
                     GGERRWLLGSASGLEDALGVIAADAIGVIAGERDGKLALCASPTCLAAFFDTSQSRTRK
                     WCDMNTCGNRQKKARFRAGRRRTPGSVE"
     gene            11799..12971
                     /locus_tag="SSPS47_RS04635"
                     /old_locus_tag="SSPS47_04740"
     CDS             11799..12971
                     /NRPS_PKS="Domain: Abhydrolase_1 (105-213). E-value:
                     4.1e-20. Score: 64.3. Matches aSDomain:
                     nrpspksdomains_SSPS47_RS04635_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009480348.1"
                     /locus_tag="SSPS47_RS04635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04740"
                     /product="epoxide hydrolase family protein"
                     /protein_id="WP_164248962.1"
                     /sec_met_domain="PF00561 (E-value: 1.3e-15, bitscore: 56.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 9.7e-09, bitscore:
                     34.8, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRPTSDVQAFETHATDADLDDLRARLAAARLPEAETVRGAAPGP
                     RRWEQGVPLADLVDVVNYWRTEYDWRSFEARLNRIGQFRTTIDDLGIHFLHRRSARADA
                     TPVILTHGWPGSIAEFTDVVDELADPKDADAPAFHVVAPSLPGFGHSDKPATTGWGTEK
                     IAAAWVELMGRLGYDKFAAHGGDWGGVITTVLGGRFPAHVLGIHSTLAQAPPGLTTDGL
                     TAGEREWTDQTRDFWRHRAAYAKQQATRPQTIGYSLVDSPVGLLAWILDKFAEWSDTED
                     SPFELISRDRVLDDVTLYWLTRTGASAARIYYESHHSLNPELRVDVPSAISMYPRDIEK
                     CPRPWAQERYRRIVRWREPEVGGHFPSLEVPGYFVRDLREGLAAVLAANR"
     aSDomain        12114..12437
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SSPS47_RS04635_Abhydrolase_1.1"
                     /evalue="4.10E-20"
                     /label="SSPS47_RS04635_Abhydrolase_1.1"
                     /locus_tag="SSPS47_RS04635"
                     /protein_end="213"
                     /protein_start="105"
                     /score="64.3"
                     /tool="antismash"
                     /translation="PVILTHGWPGSIAEFTDVVDELADPKDADAPAFHVVAPSLPGFGH
                     SDKPATTGWGTEKIAAAWVELMGRLGYDKFAAHGGDWGGVITTVLGGRFPAHVLGIHST
                     LAQA"
     gene            complement(13078..16257)
                     /locus_tag="SSPS47_RS04640"
                     /old_locus_tag="SSPS47_04745"
     CDS             complement(13078..16257)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_functions="other (smcogs) SMCOG1173: WD-40
                     repeat-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014081.4"
                     /locus_tag="SSPS47_RS04640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04745"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_164248963.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 1.3e-17, bitscore:
                     62.7, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLLKKHENLMDVTNPAPAPGPSRRHVLAVSGAVTAGALTAAGTS
                     AGRAAAAGTEQGRPAERPGGAPRTATVTVSEGTNMAAALSPDGTGLAIDVLSAVWVVPG
                     AGGAAVRLTGELQDATQPHWAPDGSRVVFQSFRDGAYQLWSVKRDGTGLTRLTDDDYDN
                     REPQYAPDGSRIVFTSDRSGSNDLWLLDPATGVRTQLTTGPDEDGTPAWSADGRTIVCT
                     VNDAAIDSVDVATGTRTRLITASAGAKIFGPAPSPDGRRVSYVQFTGTRADVMIDGQVA
                     AAGEDVHALRTSWTPDGDLLYTAGGRVRRLRPGGTPRTVDFTATVTFTRKPWTPRVRDF
                     TSRAARQARGIASPVVSRDGQRVAFRALNALWVMKTGEAPVRLADDGFFNSDPDWSPDG
                     TALVHASDRSGTAALWRRDLTGGEPVRLTSLPGAQLTPRWSPDGTKIAYQDENGATWVL
                     ELASGAVRQVLPVIFQPGRPTWSPDGAHLAVAANQPYSRRNRAGLSEVLTVDLATGATR
                     SQPVAAHRSIATRGDDGPVWTPDGKHFVFVMESTAWRVPVDPTGQITGAPEQITTEVTD
                     SLSVDTNGRLFYLSNGTLRTVPLTGGTPRTVPVPLTYRRPATARTVVLRAGAVWDGRAE
                     QLRGAADIVVKGDRIAAVRPAGQGRGDTVVDLSGLTAMPGLVDAHLHWHLRGRQWGDRT
                     GRLLLSYGITTVLSPGDPAYQMVETREAIESGAQVGPRFFGTGDALDGARVFWNFARPV
                     VGTDQLRLEMERAERLSYDLVKTYIRLQAPLERAVTRQAHERGLLVTSHYAYPHAAYGM
                     DAMEHTGGGNRVGYSQTQTRLGRAYEDAIAVLTAASMPVTSTLMNSSVLLADDRSLVTD
                     ERTRLLYPPWDYTVLVAKADAAGGPDAGLNRALLAGGVDMLLRVQRGGGSVIAGSDAPL
                     DDPALSLHQNLRAMVRGGFTPYEALRTATANPVRRMGMDSDLGMLEAGMLADLVFVEGD
                     PLRDIDAAAAVRTVVTGGTVRTVSSLLEPFRATGTRSPAANLKERSLVSARTERRYGWQ
                     DPRPGGTGCLC"
     gene            complement(16262..17578)
                     /locus_tag="SSPS47_RS04645"
                     /old_locus_tag="SSPS47_04750"
     CDS             complement(16262..17578)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (102-428). E-value:
                     1.9e-26. Score: 85.0. Matches aSDomain:
                     nrpspksdomains_SSPS47_RS04645_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004992998.1"
                     /locus_tag="SSPS47_RS04645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04750"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_239064777.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.3e-24, bitscore:
                     84.9, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAGAGVVLRRERLHSSLGSPAMGSINFLNEVMGRFPDALSFAPG
                     APHISFFDQIDVPRHIDRYLRHLTEDRGLKPDQAERLLYQYGPSRGLIGDLVAGALRTD
                     QGIDVPPESVVITVGCQEAMLLALRALAAEPTDLVAVVNPCFVGLSGAAGLLGVDLVPV
                     DDTDDGIDFAQLDDVCRAAREAGRRIRALYVAPDFSNPSGGFLSLADRHRLLDVAARED
                     FLLLEDNAYAFTAHQPGALPPLKALPGGERVVHLGTFAKVCMPGARVGYVVADQRVRDA
                     SGRTGLLADELATLKSMVTVNTSPIAQAVVGGILLEHRGSLASVVSAKAALYQRNLRLL
                     LDALDHALGPGTGAPAGVSWNRPRGGFFVRVRLPVPADERLLERSAREFGVLWTPMSHF
                     YLGSGGDYQLRLACSYLDPDAIKEGVARLARFLHAVCPS"
     aSDomain        complement(16295..17272)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SSPS47_RS04645_Aminotran_1_2.1"
                     /evalue="1.90E-26"
                     /label="SSPS47_RS04645_Aminotran_1_2.1"
                     /locus_tag="SSPS47_RS04645"
                     /protein_end="428"
                     /protein_start="102"
                     /score="85.0"
                     /tool="antismash"
                     /translation="TDQGIDVPPESVVITVGCQEAMLLALRALAAEPTDLVAVVNPCFV
                     GLSGAAGLLGVDLVPVDDTDDGIDFAQLDDVCRAAREAGRRIRALYVAPDFSNPSGGFL
                     SLADRHRLLDVAAREDFLLLEDNAYAFTAHQPGALPPLKALPGGERVVHLGTFAKVCMP
                     GARVGYVVADQRVRDASGRTGLLADELATLKSMVTVNTSPIAQAVVGGILLEHRGSLAS
                     VVSAKAALYQRNLRLLLDALDHALGPGTGAPAGVSWNRPRGGFFVRVRLPVPADERLLE
                     RSAREFGVLWTPMSHFYLGSGGDYQLRLACSYLDPDAIKEGVARL"
     gene            complement(17575..19044)
                     /gene="dpgC"
                     /locus_tag="SSPS47_RS04650"
                     /old_locus_tag="SSPS47_04755"
     CDS             complement(17575..19044)
                     /EC_number="1.13.11.80"
                     /GO_function="GO:0016702 - oxidoreductase activity, acting
                     on single donors with incorporation of molecular oxygen,
                     incorporation of two atoms of oxygen [Evidence IEA]"
                     /GO_process="GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: ECH (291-397). E-value: 7.6e-18. Score:
                     56.6. Matches aSDomain:
                     nrpspksdomains_SSPS47_RS04650_ECH.1"
                     /codon_start=1
                     /gene="dpgC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020122449.1"
                     /locus_tag="SSPS47_RS04650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04755"
                     /product="(3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase
                     DpgC"
                     /protein_id="WP_239064778.1"
                     /transl_table=11
                     /translation="MSTSGSPRSVSAPAAAPADGGELSAAGLALAAEIRDREAPLAALP
                     PRSDRSEEQQLGAAAIHRACRELRAAFLRAHAAAVYDRLTEGRTARLGLTELAGAAAES
                     FPGLVPDGAQLAEELRHAQADKEGREIDQGIFFREILRLPGAGAHLVDVMRDPTPRAHA
                     LLPDFRATGRAELGKVTVERQGDGGHVTFHNDSCLNAEDNDLIAQLEVAVDLVLLDDGI
                     RVGVLRGGPMTHPRYRGRRVFSAGVNLADLHHGRISFTGFLLQRELGYISKMYRGLSTL
                     GRPDTFPAHGVEKPWVAAVETFAIGGGTQLLLVMDKVIAAADSYLSLPAAQEGIVPGAA
                     NFRLARLTGGRVARQAVLGGRKIWAGEPDARLLIDEVVDPKAMDRAVEDAVTQLAAPAV
                     LANRRMLRVSEEPVDVFRAYMAEFSLVQAERLYGEDVLDKVGRFSARSGTGPSATDPPK
                     SGTESGTESGTEPGAAAGTRTDTHAGAETGR"
     aSDomain        complement(17854..18171)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SSPS47_RS04650_ECH.1"
                     /evalue="7.60E-18"
                     /label="SSPS47_RS04650_ECH.1"
                     /locus_tag="SSPS47_RS04650"
                     /protein_end="397"
                     /protein_start="291"
                     /score="56.6"
                     /tool="antismash"
                     /translation="VEKPWVAAVETFAIGGGTQLLLVMDKVIAAADSYLSLPAAQEGIV
                     PGAANFRLARLTGGRVARQAVLGGRKIWAGEPDARLLIDEVVDPKAMDRAVEDAVTQLA
                     AP"
     gene            complement(19127..19891)
                     /gene="dpgB"
                     /locus_tag="SSPS47_RS04655"
                     /old_locus_tag="SSPS47_04760"
     CDS             complement(19127..19891)
                     /EC_number="4.2.1.17"
                     /GO_function="GO:0004300 - enoyl-CoA hydratase activity
                     [Evidence IEA]"
                     /GO_process="GO:0033072 - vancomycin biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: ECH (77-193). E-value: 5.7e-15. Score:
                     47.2. Matches aSDomain:
                     nrpspksdomains_SSPS47_RS04655_ECH.1"
                     /codon_start=1
                     /gene="dpgB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF042431.2"
                     /locus_tag="SSPS47_RS04655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04760"
                     /product="enoyl-CoA-hydratase DpgB"
                     /protein_id="WP_164248965.1"
                     /transl_table=11
                     /translation="MSGTDTDTPNALTVRLHDEAAAVLTVGDEELTPALVDRVRTAAEK
                     AEGADRGVVLLLLGGAGAAEGASPVGTGIHLVNTWERALRRLETSGRPTLALVEGTCTG
                     PALEALLTADYRIAAGDARLRLPGAEDGAWPSTALHRLAQQIGTARARRLLLRRPWLDG
                     EQAADLDLVDETADGGEAALRRAVLVAGELSAVPGREWSIRRRLLFDATLSYEEALGAH
                     LAACDRSLRRRTTAGQSAAEQAPADGSLAQAR"
     aSDomain        complement(19313..19660)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SSPS47_RS04655_ECH.1"
                     /evalue="5.70E-15"
                     /label="SSPS47_RS04655_ECH.1"
                     /locus_tag="SSPS47_RS04655"
                     /protein_end="193"
                     /protein_start="77"
                     /score="47.2"
                     /tool="antismash"
                     /translation="NTWERALRRLETSGRPTLALVEGTCTGPALEALLTADYRIAAGDA
                     RLRLPGAEDGAWPSTALHRLAQQIGTARARRLLLRRPWLDGEQAADLDLVDETADGGEA
                     ALRRAVLVAGEL"
     gene            complement(20001..21203)
                     /gene="dpgA"
                     /locus_tag="SSPS47_RS04660"
                     /old_locus_tag="SSPS47_04765"
     CDS             complement(20001..21203)
                     /EC_number="2.3.1.246"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /GO_process="GO:0033072 - vancomycin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="dpgA"
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024: chalcone and stilbene synthase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018838205.1"
                     /locus_tag="SSPS47_RS04660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04765"
                     /product="3,5-dihydroxyphenylacetyl-CoA synthase DpgA"
                     /protein_id="WP_164248966.1"
                     /sec_met_domain="Chal_sti_synt_C (E-value: 1.5e-19,
                     bitscore: 69.3, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATEPTAPASAAVPTEPATRAPGQRLSTANAGPRPSVVGFGTAT
                     PANSYTQREMLELFGIEDPRIRSVFLNSAIERRYLTLPPELADGTRKTETQGELLAKHK
                     EQGVRTGREALETALKRAGLALSDVGYLCCVTTTGLLTPGFSAHLVKEAGLPVSTGRLD
                     VVGMGCNAGLNAMAAVASWSAANPGQAAVMVCAEVCSAAYVFDGTMRTSVVNSLFGDGA
                     AAVVMVTDPAGTARAAHGAHATKTAEADEAAPVGTVLKAASRIIPEAVDAMRYDWDDDQ
                     GKFSFFLDRDVPYVVGANAEEVVDRLLGGTGLERADIDHWLVHSGGKKVIDSVKVNLGL
                     STYALRHTTGVLRDYGNLSSGSFLFSYERLMEEGRVRRGDYGVLMTMGPGSTIETALLQ
                     W"
     gene            complement(21200..22444)
                     /locus_tag="SSPS47_RS04665"
                     /old_locus_tag="SSPS47_04770"
     CDS             complement(21200..22444)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (167-407). E-value:
                     1.6e-16. Score: 52.3. Matches aSDomain:
                     nrpspksdomains_SSPS47_RS04665_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1109: 8-amino-7-oxononanoate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004978577.1"
                     /locus_tag="SSPS47_RS04665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04770"
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_164248967.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.8e-14, bitscore:
                     52.3, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRTIERHNWVATRVDKTSDALTRAIATDLTSHVFTGREGKEVTL
                     ADGRSAVEFISCSYLGLDTHPALVEAAVASLRRVGVQFSSSRTRMRYEDLESLERMLGV
                     IYGGRHATCFTAVGSVHLGVLPLLGTGVLPSYPVSASGVTFLIERTAHASIQVLRGVLE
                     QIGDVDRFDCEDLDDLAVRLAAVRDAGRTPIVLVDGVGSMGGLIDVAALYDLCAAAEGY
                     LYVDDAHGVSITGEQGAGFAYEEFRHLPGGLPASVILVGSLAKAFGGSNGGFVLLNTEE
                     DTVELRRFGNPLIFGGPIALPVISACRASAELHLDGTVARLQRDLWRNTELFDSRTGGA
                     LFNAGTRSPIRGALFKSEEDALVTAARLRKAGVIVTPAFFPTVAKGSGLIRMAVSAAHT
                     TEQIELATNELEVPA"
     aSDomain        complement(21224..21943)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SSPS47_RS04665_Aminotran_1_2.1"
                     /evalue="1.60E-16"
                     /label="SSPS47_RS04665_Aminotran_1_2.1"
                     /locus_tag="SSPS47_RS04665"
                     /protein_end="407"
                     /protein_start="167"
                     /score="52.3"
                     /tool="antismash"
                     /translation="VDRFDCEDLDDLAVRLAAVRDAGRTPIVLVDGVGSMGGLIDVAAL
                     YDLCAAAEGYLYVDDAHGVSITGEQGAGFAYEEFRHLPGGLPASVILVGSLAKAFGGSN
                     GGFVLLNTEEDTVELRRFGNPLIFGGPIALPVISACRASAELHLDGTVARLQRDLWRNT
                     ELFDSRTGGALFNAGTRSPIRGALFKSEEDALVTAARLRKAGVIVTPAFFPTVAKGSGL
                     IRMAVSAAHTTEQIELAT"
     gene            complement(22559..23926)
                     /locus_tag="SSPS47_RS04670"
                     /old_locus_tag="SSPS47_04775"
     CDS             complement(22559..23926)
                     /NRPS_PKS="Domain: AMP-binding (104-305). E-value: 1.4e-07.
                     Score: 22.3. Matches aSDomain:
                     nrpspksdomains_SSPS47_RS04670_AMP-binding.1"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SSPS47_RS04670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SSPS47_04775"
                     /product="phenylacetate--CoA ligase family protein"
                     /protein_id="WP_164248968.1"
                     /transl_table=11
                     /translation="MLGEMYPTSHHSEARAGESSKIELAENLDILTRAQLEEMQQRNLA
                     RTVEALKRNPAVAACWPGALDVRVPRDLLKLPLFSPADLQASCPPASENLVLGDGRSGL
                     VLRSSGTSGRRKMIYHSWEFSRRVSALGARGVRSALRPHPRRIANFLYPGELNGAFTFA
                     QEVTELLPAMSFPMGSSALASPETAQLLRENQVDAVVCSPSAGTGLLTGDATRELLRGV
                     DSLLYIGEILGESRERQLADARPDLRVRSFSYSTSETGPVGYQCTYQSGSTHHLHEDVL
                     VVEVVDTDAERIQPDGRIGEVVVTMLTDSGMPLLRYRIGDEGFIETRPCLCGSAARQLT
                     LTGRVGMSMNVDSTTISRDLVMEQLATLGISDPADCQFQVTQHDPGFSIRLLVSERTPP
                     SVTTEDAVAALHGAYHMGRVFTAPLYRGLTLERVDSSEFHHTARGKTPFFVNRTAG"
     aSDomain        complement(23012..23614)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SSPS47_RS04670_AMP-binding.1"
                     /evalue="1.40E-07"
                     /label="SSPS47_RS04670_AMP-binding.1"
                     /locus_tag="SSPS47_RS04670"
                     /protein_end="305"
                     /protein_start="104"
                     /score="22.3"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="VLRSSGTSGRRKMIYHSWEFSRRVSALGARGVRSALRPHPRRIAN
                     FLYPGELNGAFTFAQEVTELLPAMSFPMGSSALASPETAQLLRENQVDAVVCSPSAGTG
                     LLTGDATRELLRGVDSLLYIGEILGESRERQLADARPDLRVRSFSYSTSETGPVGYQCT
                     YQSGSTHHLHEDVLVVEVVDTDAERIQPDGRIGEVVVT"
     misc_feature    complement(24021..24034)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.82"
                     /tool="antismash"
     misc_feature    complement(24024..24040)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.81"
                     /tool="antismash"
     gene            complement(24070..24921)
                     /locus_tag="SSPS47_RS04675"
                     /old_locus_tag="SSPS47_04780"
     CDS             complement(24070..24921)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (15-256). E-value: 2.6e-58. Score:
                     189.1. Matches aSDomain:
                     nrpspksdomains_SSPS47_RS04675_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014061288.1"
                     /locus_tag="SSPS47_RS04675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04780"
                     /product="enoyl-CoA hydratase-related protein"
                     /protein_id="WP_164248969.1"
                     /transl_table=11
                     /translation="MSELRYGEYILVHRTHNGRIAELVLNRPERMNAVSADFGAALADA
                     TADLGHDLSVGVTVITSRCERAFCVGADLKERAGYTEADRAAARPGSRAAYAGVLALPM
                     PVVAAVQGYALGGGYEIALSCDVIVADPGATVGLPETTVGVIPGGGGTQLLPRRVGAAV
                     AAQLIFSGRRVPATEARDLGLVDVLAPAGAVRATALDLARTYAANSPVALRAAKRALRL
                     GQGRDLAAGLEVEDAAWHTVAFSADWAEGVAAFNGRRPPEWPGYGTADRKGNRPAAANV
                     PP"
     aSDomain        complement(24154..24876)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SSPS47_RS04675_ECH.1"
                     /evalue="2.60E-58"
                     /label="SSPS47_RS04675_ECH.1"
                     /locus_tag="SSPS47_RS04675"
                     /protein_end="256"
                     /protein_start="15"
                     /score="189.1"
                     /tool="antismash"
                     /translation="HNGRIAELVLNRPERMNAVSADFGAALADATADLGHDLSVGVTVI
                     TSRCERAFCVGADLKERAGYTEADRAAARPGSRAAYAGVLALPMPVVAAVQGYALGGGY
                     EIALSCDVIVADPGATVGLPETTVGVIPGGGGTQLLPRRVGAAVAAQLIFSGRRVPATE
                     ARDLGLVDVLAPAGAVRATALDLARTYAANSPVALRAAKRALRLGQGRDLAAGLEVEDA
                     AWHTVAFSADWAEGVAAFN"
     misc_feature    24986..25000
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.25"
                     /tool="antismash"
     misc_feature    25189..25203
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.42"
                     /tool="antismash"
     misc_feature    25195..25211
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.03"
                     /tool="antismash"
     misc_feature    complement(25199..25213)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.31"
                     /tool="antismash"
     gene            25229..26230
                     /locus_tag="SSPS47_RS04680"
                     /old_locus_tag="SSPS47_04785"
     CDS             25229..26230
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012422.4"
                     /locus_tag="SSPS47_RS04680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04785"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_164248970.1"
                     /transl_table=11
                     /translation="MPAHHVDRSPLPIDEEITSAYAFLCGSGNASVEQIAAALEIGIER
                     ARQLVGRLTELHLIDSAGDGTYTPGSPRALGAGVIAPAIRELESGQQQIIRMMTELDAL
                     TKIYERSPAERLRRPRIEILPEVTAVRAVLTELSAGARTEILTSQPGGARPADVLRESL
                     ERTEAVLSRGITMRTVYQYTAQFSQVTVDYVRHVTERGVEVRMLGDALMRMIIFDREIA
                     VLPQYDRDGAVVVSDRSIVDFAVQAFERAWPVARPFPVSYDRGQVKSTSVEIQLSISRL
                     LVEGLEDKVIARRMGMSLRTCQRHISEIMSRIGARNRMHAGYLLGKLIDSQN"
     misc_feature    25394..25396
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(26252..27583)
                     /locus_tag="SSPS47_RS04685"
                     /old_locus_tag="SSPS47_04790"
     CDS             complement(26252..27583)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SSPS47_RS04685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SSPS47_04790"
                     /product="MFS transporter"
                     /protein_id="WP_164248971.1"
                     /transl_table=11
                     /translation="MTGTATETGTPKAGWYPRAVGAGLGFTLLSNFGLAMVLTLLPVAV
                     LHGGRIEPSVFSFALSVHVGSALVGALVTPIAFSRVHPAWVLTIASSLKAAGFVTVAVS
                     TSAPALYLFAVLAGLGVGISRPAVRSLLVAAATDDRRSQVFQVFFILLNTAYVLAPLAA
                     GPVGRAGVPALLVLAVVETVIGITVGLLARGLDFALPPRGANGLRGRLTVLRTPAVAVV
                     LGYTFAIYFAMGFLYAMILLYEVVNPAQAEHRTLFLSFQPLAIIAIQLALLPFFTRLRR
                     RALYLIVAVGGGTGLVLSFSGSLTLILAGLTLFAVAECLAFPKIQVEAADTVPQTRLTD
                     VIGLVSLVTAIGEICGNMAAGLAVSTSASWLPQPAHFGMGVGVLAGLVLLVGGLAVTRY
                     VVPSGAAKATREVAPGGSADGSPDGSPDDSPDASPGASSARDLS"
     gene            complement(27580..28545)
                     /locus_tag="SSPS47_RS04690"
                     /old_locus_tag="SSPS47_04795"
     CDS             complement(27580..28545)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF020032.4"
                     /locus_tag="SSPS47_RS04690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04795"
                     /product="hypothetical protein"
                     /protein_id="WP_164248972.1"
                     /sec_met_domain="RimK (E-value: 3.5e-07, bitscore: 28.7,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANERLVTWICHPDDFLPEYVDKITEQMTERWAEPCARHGFAFRF
                     ISANELVPACDERPRLWHDGVDLLRTRQAYIVDDVSGDPQATHFLRGIYRAIDASDSVL
                     LNRSLVGPECLERDKLAILARASTLGVRVPKTVALPFGRYARKGLDVVRKEIGEGPYIL
                     KAREMGIGFGVLKLDSYEQLRAAVDIASQTGQSYIVQEYLPNKGDLRVAMVDGKFAASM
                     LRSPAEGAYLANITQGGSSSANPDVATVLGDVERIVADLQAGYLCVDWLLTDDGPVLGE
                     WGTAMAEFSSMPEPARSQLADAFFPWVGRLLSEPAPAHSA"
     gene            complement(28731..30164)
                     /locus_tag="SSPS47_RS04695"
                     /old_locus_tag="SSPS47_04800"
     CDS             complement(28731..30164)
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018551353.1"
                     /locus_tag="SSPS47_RS04695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04800"
                     /product="transcription antitermination factor NusB"
                     /protein_id="WP_147877584.1"
                     /transl_table=11
                     /translation="MNEQARRRPSKTYRRPKKDPVRILAFEALRAVDERAAYANLVLPP
                     LLKKAREAGDFDNRDAALATELVYGTLRRQGTYDAIISACIDRPLRQVDPPVLDVLALG
                     AHQLLGTRIPTHAAVSASVELARVVLGDGRAKFVNAVLRKISKDGLDAWVERVAPPYDE
                     DAEDHLAVVHSHPRWIVSALWDALGGGRAGIEDLLEADNERPEVTLVARPGRVSADALL
                     DTLGEESGLPGRWSPYAVRLTEGGEPGAIDAVREGRAGVQDEGSQLVAVALANAPLEGT
                     DSRWLDGCAGPGGKAALLAALAAERGARLLASEKQPHRARLVERALAGNPGPYQVITAD
                     GTRPPWRPGVFDRVLVDVPCTGLGALRRRPEARWRRRPEDLEGFAPLQRSLLREALKAV
                     RVGGVVGYATCSPHLAETRVVVEDVLKGRGGPAAEAEWVDARPLMPGVAALGEGPDVQL
                     WPHVHGTDAMYLALLRRTA"
     gene            complement(30248..31204)
                     /gene="fmt"
                     /locus_tag="SSPS47_RS04700"
                     /old_locus_tag="SSPS47_04805"
     CDS             complement(30248..31204)
                     /EC_number="2.1.2.9"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fmt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1228: methionyl-tRNA formyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003947011.1"
                     /locus_tag="SSPS47_RS04700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04805"
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="WP_147877585.1"
                     /transl_table=11
                     /translation="MKLVFAGTPEVAVPALDALIASDRHEVAAVVTRPDAPAGRGRRLV
                     ASPVAQRAEEEGIEILRPARPRDEAFLTRLREIAPDCCPVVAYGALLPRVALDIPANGW
                     VNLHFSLLPAWRGAAPVQHAVIAGDETTGAATFLIEEGLDSGPVYGVITEDVRPTDTSG
                     DLLTRLAFAGAGLLAATMDGIEDGTLKAVQQPTEGISLAPKLTVEDARVDWAAPALRVD
                     RVVRGCTPAPGAWTVFRGERLKLIQLKPVPDRTDLAPGEPAVGKNSVHVGTGSYAVELL
                     WVQPQGKKPMRAADWARGVRIAPGERLGAAEGAADVR"
     misc_feature    complement(31189..31203)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.72"
                     /tool="antismash"
     gene            31484..32020
                     /locus_tag="SSPS47_RS04705"
                     /old_locus_tag="SSPS47_04810"
     CDS             31484..32020
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019066412.1"
                     /locus_tag="SSPS47_RS04705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04810"
                     /product="hypothetical protein"
                     /protein_id="WP_164248973.1"
                     /transl_table=11
                     /translation="MADHATHDAQARANLHLLVRDIERVRRQVDALRTLTAQLGNVYRP
                     RRSGPSTGFVVYGRAPAPTVRLAQELRDSVESLVTAAVDFDRSLGFSWDAVGSALGVTK
                     QAVHRRYGTRRAAQQSAPAEGERPADSAQPRPSGPAQGVPAVPAARSMPPQPTVAPQPL
                     REEARPGAFPGPRNG"
     gene            complement(32167..34314)
                     /locus_tag="SSPS47_RS04710"
                     /old_locus_tag="SSPS47_04815"
     CDS             complement(32167..34314)
                     /EC_number="3.6.1.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003678 - DNA helicase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044799.1"
                     /locus_tag="SSPS47_RS04710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04815"
                     /product="primosomal protein N'"
                     /protein_id="WP_164248975.1"
                     /transl_table=11
                     /translation="MSSDDEQSEESAGGGGPEQLAFIRETVRAAKVPRAKPRTWRGAPL
                     AAELPVARVVVNKGVLHLDQFFDYAVPEELDEAAQPGVRVRVRFGAGAHQVRGGRREGG
                     RLIDGFVVERRAESDYTGPLAALAGVVSPEPVLSPELLGLARAVADRYAGSLADVLQLA
                     VPPRNARAEARPSPDPLPAPGRPETGTWERYAKGAAFLDALADGGSPRAVWTALPGPHW
                     AQELARAVTATLASGRGALVVVPDGRAAARVDTALTALLGEGHHALLTAEAGPQKRYGQ
                     WLAVRRGAVRAVVGTRAAMFAPVRDLGLVAIWDDGDSSHSELHAPLPHAREVLLLRAAH
                     DKCAFLLGSTGCTVEAAQLVETGWALPMTADRERFRTAAPLIRTVGDGELARDEAARAA
                     RLPSLAWQAVREGLRTGPVLVQVPRRGYVPRLGCERCRAPARCRHCAGPLEAPEQRELH
                     CGWCGRGEPAWRCAECGGTRLRASVVGARRTAEELGRAFPAVPVRTSGRDHILDTVPGR
                     PALVVSTPGAEPVAEGGYAAALLLDGWAMLGRPDLRAGEEALRRWLHAASLVRGQADGG
                     TVVVVAEPTLRPVQALVRWDPVGHAQRELAERAELGFPPVSRMAAVTGGPDAVAAFLAA
                     AELPPDAEVLGPVPLPVTDPARPRRTGDQPPGEVWERALLRVPPGSGAALATALKSAQA
                     GRLARGGGDPVRIRIDPPDIG"
     gene            complement(34454..35662)
                     /gene="metK"
                     /locus_tag="SSPS47_RS04715"
                     /old_locus_tag="SSPS47_04820"
     CDS             complement(34454..35662)
                     /EC_number="2.5.1.6"
                     /GO_function="GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="metK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009187586.1"
                     /locus_tag="SSPS47_RS04715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04820"
                     /product="methionine adenosyltransferase"
                     /protein_id="WP_147877588.1"
                     /transl_table=11
                     /translation="MSRRLFTSESVTEGHPDKIADQISDTILDALLREDPTSRVAVETL
                     ITTGLVHVAGEVTTKAYAPIAKLVRDKVLEIGYDSSKKGFDGASCGVSVSIGAQSPDIA
                     QGVDTAYEKRVEGEGDELDKQGAGDQGLMFGYACDETPELMPLPIHLAHRLSRRLSEVR
                     KNGTIPYLRPDGKTQVTIEYDGDKAVRLDTVVVSSQHASDIDLDSLLAPDIREFVVEHV
                     IKQLLEDGIKLETEGYRLLVNPTGRFEIGGPMGDAGLTGRKIIIDTYGGMARHGGGAFS
                     GKDPSKVDRSAAYAMRWVAKNVVAAGLASRCEVQVAYAIGKAEPVGLFVETFGTASVDV
                     EKIEQAIATVFDLRPAAIIRDLDLLRPIYAQTAAYGHFGRDEPDFTWERTDRVDALREA
                     AGL"
     misc_feature    35713..35732
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 23.35"
                     /tool="antismash"
     gene            complement(35922..37172)
                     /gene="coaBC"
                     /locus_tag="SSPS47_RS04720"
                     /old_locus_tag="SSPS47_04825"
     CDS             complement(35922..37172)
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /GO_function="GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA]"
                     /GO_function="GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA]"
                     /GO_process="GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0015939 - pantothenate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="coaBC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013005041.1"
                     /locus_tag="SSPS47_RS04720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04825"
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="WP_164254386.1"
                     /sec_met_domain="Flavoprotein (E-value: 3.2e-31, bitscore:
                     106.6, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRTERSQEPGRPGGGGPGVVLGVSGGIAGYKACELLRRLTESGH
                     DVRVVPTASALHFVGAATWSALSGHPVSTEVWSDVHEVPHVRIGQSADLVVVAPATADL
                     LAKAAQGLADDLLTNTLLTARCPVVFAPAMHTEMWEHPATRANVATLRERGAVVIEPAV
                     GRLTGVDTGKGRLPDPGAIFEVCRRLLARGVSTPDLAGRHVVVSAGGTREPLDPVRFLG
                     NRSSGKQGYALARTAAARGARVTLIEANTGLPDPAGVDVVRVGTAVQLREAVLKSAADA
                     DAVVMAAAVADFRPASYAEGKIKKKDGEEPAPIVLVRNPDILAEIGAERARPGQVIVGF
                     AAETDDVLANGRAKLRRKGCDLLVVNEVGERKTFGAEENEAVILAADGGETPVPYGPKE
                     ALADTVWDLVVPALGSA"
     misc_feature    37174..37189
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.48"
                     /tool="antismash"
     gene            complement(37289..37561)
                     /gene="rpoZ"
                     /locus_tag="SSPS47_RS04725"
                     /old_locus_tag="SSPS47_04830"
     CDS             complement(37289..37561)
                     /EC_number="2.7.7.6"
                     /GO_component="GO:0000345 - cytosolic DNA-directed RNA
                     polymerase complex [Evidence IEA]"
                     /GO_function="GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="rpoZ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006382157.1"
                     /locus_tag="SSPS47_RS04725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04830"
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="WP_023542989.1"
                     /transl_table=11
                     /translation="MSSSISTPEGIINPPIDELLEATDSKYSLVIYAAKRARQINAYYS
                     QLGEGLLEYVGPLVDTHVHEKPLSIALREINAGLLTSEAIDGPAQ"
     gene            complement(37643..38206)
                     /gene="gmk"
                     /locus_tag="SSPS47_RS04730"
                     /old_locus_tag="SSPS47_04835"
     CDS             complement(37643..38206)
                     /EC_number="2.7.4.8"
                     /GO_function="GO:0004385 - guanylate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /gene="gmk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017945587.1"
                     /locus_tag="SSPS47_RS04730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04835"
                     /product="guanylate kinase"
                     /protein_id="WP_164248977.1"
                     /transl_table=11
                     /translation="MAPEVHPRLTVLSGPSGVGKSTVVAHMRKVHPEVWLSVSATTRKP
                     RPGERHGVQYFFVTDEEFDKLVANGELLEWAEFAGNRYGTPRLAVQRRLEAGEPVLLEI
                     DLQGARQVKDSMPDSQLVFLAPPSWDELVRRLTGRGTESPEVIERRLVAAKVELAAESE
                     FDISLVNTSVEDVARELLALMAVV"
     gene            complement(38245..38568)
                     /locus_tag="SSPS47_RS04735"
                     /old_locus_tag="SSPS47_04840"
     CDS             complement(38245..38568)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003977346.1"
                     /locus_tag="SSPS47_RS04735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04840"
                     /product="integration host factor"
                     /protein_id="WP_003970367.1"
                     /transl_table=11
                     /translation="MALPPLTPEQRAAALEKAAAARRERAEVKNRLKHSGASLHEVIKQ
                     GQENDVIGKMKVSALLESLPGVGKVRAKQIMERLGISESRRVRGLGSNQIASLEREFGG
                     SPA"
     gene            complement(38802..39695)
                     /gene="pyrF"
                     /locus_tag="SSPS47_RS04740"
                     /old_locus_tag="SSPS47_04845"
     CDS             complement(38802..39695)
                     /EC_number="4.1.1.23"
                     /GO_function="GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA]"
                     /GO_process="GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003970366.1"
                     /locus_tag="SSPS47_RS04740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04845"
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="WP_275405139.1"
                     /transl_table=11
                     /translation="MNDATVTAASVGADTEREPFGARLRRAMDTRGPLCVGIDPHASLL
                     HDWGLSDDVAGLTAFTRTVVEALADRVAVLKPQSAFFERFGSRGVAVLEKAVAEARAAG
                     ALVLMDAKRGDIGSTMGAYAATYLDKDSPLFSDALTVSPYLGFGSLRPALDAARVSGSG
                     LFVLALTSNPEGAEVQRATTQGGCSVAQTMLDHAAAENAGATPLGSVGAVVGATLAEAG
                     VNLAINGPLLAPGIGAQGATPADLPAVFGAAVGDVVPSVSRGVLRHGPDVYVLRAAAER
                     FGDDVRTAVEGARRAR"
     gene            complement(39692..40801)
                     /locus_tag="SSPS47_RS04745"
                     /old_locus_tag="SSPS47_04850"
     CDS             complement(39692..40801)
                     /EC_number="1.3.5.2"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005319883.1"
                     /locus_tag="SSPS47_RS04745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSPS47_04850"
                     /product="quinone-dependent dihydroorotate dehydrogenase"
                     /protein_id="WP_164248979.1"
                     /transl_table=11
                     /translation="MYRLLFRLLFRRMDPEQAHHLAFRWIGLVVRVPVLRTFVAAALAP
                     RYEALRTEAFGLRMHGPFGLAAGFDKNAVAVDGMSMLGFDHVEIGTVTGQPQPGNAPQR
                     LFRLPADRALINRMGFNNDGSATVALRLATRREIFRTTVGVNIGRTKAVPDDAAIGDYV
                     TSTERLAAHADYLVVNVSSPNTPGLRNLQAVDQLRPLLTAVREAADHVVPQRRVPLLVK
                     IAPDLADDDIDAVADLAVELGLDGIIATNTTVARHGLGLKTAPSLLAETGGLSGAPLKA
                     RSLEVLRRLYARVGDRITLVGVGGIENAEDAWQRILAGATLVQGYSAFIYQGPFWSRGI
                     HKGLAARLATSQYATLAEAVGADTRKAHA"
     misc_feature    41015..41030
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.11"
                     /tool="antismash"
     misc_feature    41168..41183
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.03"
                     /tool="antismash"
ORIGIN
        1 gcgactcgtc ggcgtgggcc gcggccgttc gtggatccgc ccgtggccct ttgtacccaa
       61 cggtgttgcg gcggccgtag ggcttcgcgc ccccgacgga gagggccagc gcggatctcg
      121 cgcgacacgc acaccgcgga ccgctggacg gggcaaagcc gccttctccc cgaatccggg
      181 cagtgcccgc acagcgaaac ccttccgaca tggtcactct tcgccgtcgc ggcgcgctgc
      241 ctcacccgtg aagtccccct ggcgcacccg gccgccccac ctttccggca cgggcccggc
      301 cgggtcgaca ccgctccgcg ctccggcctc ccattcctct tcgaggatgc cgaacatcag
      361 ggagtcccgc cagccgtccc ggatccatgc cgtgtgtcgg tggtgcccct cgtacgtcat
      421 tccgagcttt gccagcactc gagaggatcc gagattccgc gggtcgcagg tggcgtagat
      481 ccggtgaagc cccaactggt cgaagccgag cgacaggagc gagcgcccga cctccgtgcc
      541 gagaccccgc ccccatactc gcggatgcac gaggtaggag atctccccct gtcggtaggt
      601 gtgactgcga acgcgcaact cccccatacc gacaacggcg ccctcgaagc gcaccacgtg
      661 ggcgaagcgc tgccgaggtt cgtgcgacca ggcctcgacc gcggccttca cgaagtcgcg
      721 cgtctggtcc tcggtgttgg gcccccaagg ctggaaccga cacgcctccg cgagacgggc
      781 ccacgagtgg acgtcccgcc agtcgtcgag agcgatcctg tccagggtca ccgagcactc
      841 actcatcggt agatcgtgtc agacgtagcg gacagggagg cggattccag aagcacgtgc
      901 tcatcgccct cgggcagatc gcagaagacg ccggagtggg ttcgtcgggc ctccgtcgcc
      961 gccgcgtgcg catgcggtgc taagcctgct gttgggtgag ggtggacagg gccgcgtcca
     1021 gccggtgggt ggcatcctcg gcgacgggct cgagagcgtc ccggccggtc agggtgacca
     1081 tcgtggcggg gtcgagggcc tggacggcga tgcgctcgcc gtcggtgcgg acgacgacgt
     1141 tgcagggcag cagcaggccg atggagcggt ccgcctcgat cgcttgacgg gcgagcggcg
     1201 ggttgcaggc gccgaggatc agatagttct ccatgtcgtg gccgagcttc tccttcagcg
     1261 tggcccgcac gtcgatctcg gtcaggatcc cgaagccctg ctcggccaga gcctcgcgca
     1321 cggccctcac ggtctcctcg aagtcgccgt ccacgtgcac agtgcggctg taggtcatcg
     1381 gcatcgcctc atcgtcgtct gctggtcccg ctttgggcgg aggccgccgg gcacccgcac
     1441 gggtgcggcg atccactcac aaaatatacc cccgggggta cgagtgttac ggtgggacca
     1501 ataccccctg gggtaatttt catgcgaaag gaatatccgc gtgttcttcg ttgacaccat
     1561 agagctggaa gggctcggca accgcagcta cctggccgga ggggagcaca cggcggtggt
     1621 tgtggacccg ccgcgtgaca tcgaccaggt cctggcggca gccgcccggc gcggtgtgcg
     1681 gatcgcgtac gtggcggaga cccacatcca caacgactac gtgaccggcg gcccggaact
     1741 cgcccggatc accggcgccc agtacctcgt gccggccggt gcgaacgtct ccttcgcgcg
     1801 ggtggctgtc gccgacggcg acaccgtgga catcgacccc ggcagcgggg tgagcctggc
     1861 cgcgatcgcg acgccgggcc acaccccgca ccacacctcc tacgcgctgc gcgagggggg
     1921 gcgtccggtg gtcgtcttca ccggcggatc gctgctgatc ggcacggtgg gccggccgga
     1981 cctggtcgaa ccgcggctga ccgaacagct cgcccgcgcc cagcacgcct ccgcccaccg
     2041 tctggcctcc ggccttccgg acgagacggc ggtgctgccc acgcacggct tcggcagctt
     2101 ctgctcctcg gcccagtccg agggggagga gaccaccatc ggcaaggaga agagcgccaa
     2161 tacggcgctc accgtcgatg tggacacatt cgtcgcagac ctgctggccg ggctggagga
     2221 cgtgcccgcc tactacgcgc acatgggccc ggccaacgcc gcaggtccgg ccccggtcga
     2281 tctgaccccg cccgcgctcg cggaccccgc cgagatcgcc acgcggcttg cggccgggga
     2341 gtgggtggtc gacctgcgca accgcgtcgc gttcgccgag gggcacgtgg ccggttcgtt
     2401 caacttcgag gccgatggca agatcgccac ctatctcgcc tggatgatcc cctggggcaa
     2461 gccggtcacg ctgctcgccg aatcggccga gcagctcgcc gacacccagc gcgagctggt
     2521 gcgggtgggc atcgaccggc cggccgccgc cgccaccggc ggtcccgccg cctggctgcc
     2581 cgccggggag aagcccgcct ccttcccgcg ctccacgttc gccgcactcg ccgaccgcgg
     2641 cctcgaccac gtggtggtcc tggacgtgcg ccgcgactcc gagcgggcgg acggctggat
     2701 cgagggatcg gtgcacatcc ccatccacga gctccacggc cgccttgccg aggtaccgcg
     2761 gggggcggtg tgggtgcact gcgcgggcgg tatgcgcgcc gcgatcgccg catccctgct
     2821 cgacgcggca ggccgggatg tcgtcgccgt cgacgacggc ttcgacgccg ccgccggcgc
     2881 cggcctgccc ctgaccaccg gctgacccac accccagcac agcacgagaa aggggagaac
     2941 gtcatgtccc tcttccgccg cgaccagccc cgcgtcagcg cggaacgggc ccgcagccgc
     3001 accggtggca aggccccgga cgcgatcccg ctcgatgtcc gcgagaagcc ggagtggaac
     3061 gccggccacg ctcccggcgc ggtgcacgcc ccgctgtcga acctcagcgc cggcgccgac
     3121 ctgccggccg gagtatcggg cacgccactg gtggtgatct gccgcagcgg gcaccgctcc
     3181 cagcaggcgg ccgaactcct cgaccagcgc ggagagcggc cggtggacgt cgagggcggc
     3241 atggacgcgt gggccgcctc gggatacccg gtcagcgacg aacgcgggaa cagcggccgg
     3301 atagcgtgac cgccctcgtt ctcgccctca tcgccggagc cgtcatcggc ctcgccctag
     3361 gaactctggg cggcggcggc agcgtcctga ccgtacccgc cctgatctac ctgctcgact
     3421 tcaccccgcc cgcggccacc accgccagtc tgatcatcgt ggccgccacc tccgtcaccg
     3481 ccctgtacgc ccacgcacgc gacggccacg tcgcctggaa gaccggatca ctcttcgccg
     3541 ctgcgggcat cgtccctgcc tacctcgccg gagcagcctc tggtcacgta cccgaagtga
     3601 tcctgacagt ggcgttctcc ctgatcgccg cgctggcggc catgcgcatg ctccgcccct
     3661 ccacctccga accggcggac cggacaaggc ccggcaaggc gaccggggca ggcgccggac
     3721 taggcgcggt gaccggtttc ctcggcgtcg gaggcggatt ccttgccgtc ccggctctgg
     3781 tgagcgtgct cgggctgacg atgaggcggg cggtgggcac cagcctgctc gtcatcaccg
     3841 tcaactcatt cgccgccctg atcgcccgta ccggaaccgg cggcggactc cagtgggaag
     3901 tcatcacacc gttcacgggg gccgcgatcc tcggcgcctg ggacggaaaa cgcctcgcca
     3961 ccaagatctc cggccatact cttcagagag ccttcgccgg cgtgctcctg gcggtggccg
     4021 tgttcatgct catcgacgtg atcgcatgaa caagccagcc accgccgccc tcaggccaga
     4081 gacaggaaca acttctccag ccgggcccgc atctggtctc ggtcgccggc cgcctgcccg
     4141 ccctcggcca tgcagtgctg cagcccggtc gcaatgatcg cgaacccggc ccggtccagc
     4201 gcgcgggaga ccgccgcgag ctgcgtgatc acgtcctcgc agtcccggcc gtcctcgatc
     4261 atcttgatga tccccgcgat ctgcccctga gcccgccgca gccggttcag taccgacttg
     4321 agctcgccgg ccgccatctc aagctccatc atccacctcc atacgatacc cctaggggta
     4381 tcataccggg tgcggacacc cgccccggga acaccacgga aggaccaccc gcacatgaac
     4441 acccccaccg ccctcatccc cgcccaggcc gccgcacgcc tcgacgacta cacggtcatc
     4501 gacgtgcgca cccccgggga gtacgcctcc ggccatctcc ccggcgccca caacatcccc
     4561 ctcgcccacc tccacaccgc cctgcccgcc ctcaaggccg cagccacccg cggcaacctc
     4621 ctcatggtct gcgcctccgg caaccgctcc accaccgcct gcacccaact cgccgcagcc
     4681 gacatccccg ccaccaccct caccggcggc accaccgcct ggaccaccga ggggcacact
     4741 gtccaccgcc ccgcaagcgc acaggccccc tggcccatgg aacgccaggt ccgcctcgcc
     4801 gccggatccc tcgtcgtcct cggcctcgcc gcaggcaccc gctggcaccc cgcccgctgg
     4861 ctgtccgccg ccatcggcac cggcctcgtc ttctccgccg ccaccgacac ctgcggcatg
     4921 gccgctgccc tggccaagct cccgcacaac cagccccgca ccaccgacct cgacgccacc
     4981 ctgcgaaccc tggggaactg aaacactcgc cgacctgacg accgcatcgc tcggcggcgc
     5041 aaggaccatc acggcctccg gctctgccga ggggtggcat tacggctcga ccactcgtgc
     5101 gctggcggcc ggctccgtca cagggggaag acgatgaggg cggtgtcgtc gcttgcgccg
     5161 acgggcgggg ccaggagggg cgtctggacg atcatgcgag gccagacggc ttcggtaagg
     5221 cccttgagcc cgtcgcagac cagcatgagc acgtcatcca ggccgtggtt cttcagctcg
     5281 gtgaacacat gcagccagta cttcgcgccc tcgccgccgt cgccggccca gatgccgagg
     5341 atgtcgcggt gccgtccacg gtcaccgcca tcaccacgta gataggacgg ttcgcgacct
     5401 gcccgtcctt gatcttgacg ctgatggcgt ccacgaacag cacgggatag acacggtcga
     5461 ggggacggat ctgccactcg gtcatgtcct ccatcactgt gtcggtgatt ctggagatgg
     5521 tctgtttgga cacctcggcg ccgtagacct cggccaggtg agcggcgatc tcgccaagcg
     5581 tgagcccctt cgcggacagc gacagcacca tctcgtcgac cccggtcagc cgccgctgcc
     5641 gcttcttgac aagctgcggc tcgaacgtcc ccgaggtgtc acgcggcacc ttgacctcga
     5701 ccggcccgac gtcggtcagc acggtcttgg cctggcctcc gttgcgggag ttgccgctgc
     5761 cccggccgcc gacagcatgc ttctcatagc cgaggtgatc ggtgatctca ccttccagcg
     5821 cagattcccg cttggtcagc tgcagcccct ccgaccgggc ccgctccacc agcttcgcga
     5881 ccagttgctc ctcggacaca ggcgcaggct gcccggactg gacactctcg acaggctgca
     5941 cggtctccaa ctccacggcg ttgtatgtca cttgacgtct ctcccatgat cgtcggatcc
     6001 gccgtggcct gagttcctcc ggcgtgggtt cgcgcgcatc cggcatcttc gggagctcac
     6061 tcaaggggtc catcgacctc acgtacgccc tgtcctttgc cgctcgtacc tcgatctctc
     6121 caaggaccac gcccagggcc tcttcgagcg tccgggtctt ccgatctcgc cagcggccgg
     6181 gccggtcggt caggccatga gtaagctcca cgacgaggcg agaggagcgg tcaggatcca
     6241 aggactgcgg gaactcctgc ctgacactga cggtgtaagg gaggccgtcg acagcaatgt
     6301 ccactccgcc ctcgcgcggg tggaagaacg agtgggcctt ccgcacctcg caccctcgcc
     6361 ggaccgcctc agccgacagt ccctgcagca gaagaagcga ccttcggcgg agcacagaag
     6421 gcatgacgag tcggcgctcg tcgtctttga gcgcggtcac gatcggatgg aggttcccca
     6481 gtcgtgaggg aacgggaacc ggacccccgt tctccttcgg ccgttgactc cgcgcatggg
     6541 gatgcgggcc atccgcaagg aacagctcca gccccggccc accgtacgga accttctcaa
     6601 tatgcttgcc cactggttcc aggccgtgcc gtttcgcgta gttgacgacg cgccgccact
     6661 ccgcgacctc gtcgtcatca gggtcggtga tccgaacgcg gccctcagcg acgagccgct
     6721 cgatcagttc ttgagccttc gcccgtcggg cccgcgcgac gggcctctcg ctgtaggacg
     6781 tccgagggct ggcgggcact gccggctcac tggcaccagc gaccgcagag tcgtcgtcga
     6841 aagggcactg atgggtcgtc gtgaccgcca atccgcccca gcaccaatcc agcacgggac
     6901 aggttcccgc agttgctcag gggtgtcgac aggtcagcac gaaaccagca cagggacgcg
     6961 gcaaggtctc acccgccgtg cgggaccttg ctcttgacct gcaggtttgc gttctgcgcg
     7021 cccgagtgct gatcgacacg tcatctttcc attgaggaaa cgcataccga ctctctcacc
     7081 tgcggttcta cggaaagggc gggtggggag tcagctcgga gcggtgacgg tcccggctgc
     7141 ggctcctacg tcatcatcgc cgatggcacg gacttctggc gaaccggcgg agtgctttcc
     7201 gtaccttcgg cccgcggagg ccgggggtgt tcgtagcatc ggccgaagac gccggcggca
     7261 tctcgggcgc cgcccgtggc gctactcgct gtccgggtcc ttgcgctcca gcgccgggcg
     7321 ggggccgggc tcgaagtcgt gcagcaggaa gtcggccgcg gcggtgtcgg tgaccaggct
     7381 cgtgacgagc ccggatctca gaacggctcc gatggccgcg cccttgcgct ggccgcccgc
     7441 gatcgcgacg acctcgggga tacggcgcag ccggtcggcc tcgacggtga tgcaccgctc
     7501 gcccaggtcc cgtccgaccc gccggccctc cgcgtcgaag agatgcgccg acatctcggc
     7561 ctcgaccccg agggacgcgt agtgcgaacg ctcctcgtcg gtgagcatgt cgtggaccgt
     7621 ggagatcccc gcctcccagg agccgatgga gacggcggcg acggtgacct tgtcgaagta
     7681 gtcgaaggcc cgggcgatac cggtctggct gcgcagcgcg gcggcggtcg ccgggtcggg
     7741 cagcagcatc ggggcgtaga tcgggtgcgc ctcgccgccg gagacctggg cggcgcgccg
     7801 tacggcctcg acggagccgc gctcggcggt gcccgcgtcg tacacaccgg tcagctggac
     7861 gacggtgcag ggcggcaggc ggtcgagcgc ggcggccatg tggatggtgg agcggcccca
     7921 ggccaggccg aggacgtcgc cctcgaccac cagttcgccg aggaggtcgg cggcgacctc
     7981 gccgaggttc tcggggtcgg gcgactcgtc ggcgccttcg gcgggcgact ccacgacgac
     8041 cgcgtgccgc aggccgtagc gggcgcgcag ggcgtcggag cgctcggcgt ccagctcggc
     8101 cgggacgcgg atctcgatcc tcacgaggtc acgttcgagg gcggtctcca ggacccgggc
     8161 cactttgaag cggctgacgc cgaactcctc ggcgatctgg atcttggact tgccctccag
     8221 ataaaagcgg cgggccatgg ccgccgcctg caccagttcc gcgggtccca tgcgcagggc
     8281 cggccgaccc gccgacatac cagacaccgc gatctcctca ctgctgttca cactctggac
     8341 gcgctctcat cctgtcagat tcggcggtcc ttgatcagcc cggatgggcg ccgttcatga
     8401 agccgtggcc cggtggccgc gtggaatcgc gcctcagtgg gcgcaggacc agccggcgga
     8461 ggcggtcgcc tcgtcggcct ggtggcgcag catccgtacg gcagcagccg ggtcgtccgt
     8521 gccgtacacc gccgaaccgg cgacgaagac gtccgccccc gcctcggcac accgttcgat
     8581 ggtggcggcc gagacaccgc cgtcgacctg gagccacagt tcgagcccgt gcttggagat
     8641 cagctcacgg gtacggcgga tcttgggcag catgatgtcc aggaacgcct gaccgccgaa
     8701 gcccggctcc accgtcatga tcagcagcat gtccagctct ggcagcaggt cctcgtacgg
     8761 ctcgacgggc gtcgcgggct tcagcgccat cgaggcgcgc gcgcccttgg cgcggatctc
     8821 gcgtgccagc cgtacggggg ccgccgcggc ctccgcgtgg aaggtgaccg aaccggctcc
     8881 ggcctcgacg tactgcggag cccagcgatc gggttcctcg atcatcagat ggcagtccag
     8941 cggcgtctcc gtcgcgcggg cgagcgcttc gacgaccggc acaccgagag tcagattggg
     9001 cacgaagtgg ttgtccatga catcgacgtg gagccagtcg gcgccttcgg ccgctttcgc
     9061 ctcctcggcc agacgtgcga aatcggcgga caggatgctg gggttgatct gagccatgtc
     9121 ccaagcctgc catgctccgg gcgacttccc cgcctcgttg cgcggcaagg ggcccggggg
     9181 ggcaggcaca gtccgcgcaa tcctcgcgat tcgacgagtg cggtggggtg tccgggggcg
     9241 agggagcggg ggcggggcgc aggagcacgg gtccgcgggg gtggggaggg agcggagacg
     9301 tggcgcaggt gcgcagcggc ggtcgcgggt cgttcagggt cgggctggag gggccggtcg
     9361 ggccggtcgg gccggtcggg tcggtcgggt cggtcgggtc ggtcgggctt acagcggcgc
     9421 ctgtcgctcg gaccggagac gtctgcgttc gggcgtgtag tgccaccaag ggcgggccgg
     9481 ctttccttcg gcctggtcca cggcggacat gacggtgtcg aggaggcagg ggtcgagccg
     9541 ctgcccggcg gcggccgaca tccgctcgta cagttcgacc gggtcctccc ccaccagctg
     9601 agcgatcctg gtgacaccga cgccctcgaa gtaacgggcc acggaacggc cgacgttgac
     9661 cagctcggtg aggtccggct catcgtgtgt ggaggccatc aggaccactc cttctctctc
     9721 gtccggtccg tccgggccgc cggctcggcc cgctccgtac aggccgccgt acgcgtaccc
     9781 gtaccggcca cgtaaccacg cgggcccggc cgggtcttga acgaatcgga cacgcccgcg
     9841 gagtcagcgc tcgtcgcgtc cggcggtcag tgcgcggatg ccgaggatca tgacgtccat
     9901 gccggtgtcg aagtgtgact gcgggggctt cccggccggg gcgggagacg ggggttcgag
     9961 ccctgccagg gcgaacccgt tggcgaagtc gacgaacatg ccggcgcacg cgtcgatctt
    10021 gtccgccggt acgcccgccg aggtcagcgc ggcgtggagt gggccgttga tcgtctccga
    10081 cgcctgtgtg accgccaccg ggtcggtgac gatctggagt acgagccggg ggtggcgccg
    10141 ggtcaggtcc cggtaggcgt ccacccaggc acgcacctgc ccggcccagt cgtcgggtac
    10201 ggactccggc aaccgcatac gtgagaagac gagtccgacg agccccgaga cgaccgcggc
    10261 cttgttgggc agatggtggt agatcgacat gggatccaca cccagttcac gggccagccg
    10321 gcgcatgctc agggcatcga gacccgccgc gtcgacgagg gcgagggcgg tcgtcaggat
    10381 ccggtcggcg gtgagtcctg cccggtcggc ggcggggcgc ccgcgcttcc tgaccttgtc
    10441 cggttccgtt gccacctcgg catgctaccg ggccgaagcg aattcatacg ccgtagattt
    10501 ccaggtggtc gcggggcgtt cggcgaccgc cggttcagtg cgtcctgcgc cgccggccgt
    10561 gctcggcgtc ccaggactcg atgacgaggt ggtcggcggg ggtaccgaga taggtgagcg
    10621 cgacttcacg gatgtcgatc cggaagaagc ccgcgcccac gtgcgggttc cccggcgggg
    10681 ccggcgtctc cacgaggact ccggagagtt tggcgtctcc gtgccaggcc tccccctccg
    10741 gggcgtcgat cgtggggctg tggaccgcga cgcgcggatc gcgtcgggcg tcgcggagtt
    10801 tgaccgatcc gcccatcatc cccagagtga cgtcgccgtc cttgaactcc agctcaatcg
    10861 cgctgattcg gggtgagccg tcccggcgga gcgtcgcgat cgtcttgttg acgcccgccg
    10921 cgaaacacgc cgagaccttg tcggcgaact ccgggtgccc gctccggatc tcgtgccacg
    10981 tcgccatggt gcgaacctcc cgttcggtgg gcgtctcccc cacacccgca ctctacagcg
    11041 taggaatatt ttcctacacc gtagattcca gggaagctcg atgccccgcc cgggagcggc
    11101 tgcctcctgt gtggtcagct ccgacgcgtc gaggtgacga tcactcgacc gacccggggg
    11161 ttcgccgccg gccggctctg aagcgcgcct tcttctgacg attcccgcac gtgttcatgt
    11221 cgcaccattt gcgggtgcgg ctctggctgg tgtcgaagaa ggcggccagg caggttggtg
    11281 acgcgcacaa cgcgagcttt ccgtctcgtt cgcccgcgat gacgccgatc gcgtcggcgg
    11341 cgatcacgcc gagggcgtct tccaggcccg aagccgagcc gagcagccat cgccgctcgc
    11401 ccccgggcgt caggaccgcc gcggcccgcc cctgtgcgct gcggtcattg atgacctgga
    11461 cagcggactc cggcagagcg tcccggatcg cggccgctgt cgcggcggcg tgaatcgact
    11521 ccctcagctc ccgggcgagg tcgagctggg cggtggtgca ggagtccacg gcgaggccgt
    11581 tcaccgcgag ccagtcgacg agtcggtgcg gcacggggat gcgctccacg gcgttgccat
    11641 gacgctccga cagggtcccc gtgaagctgg tcgccagcac actgccgagg cggaagtcag
    11701 ggaacgcggc acacataaaa ccaccttagc cggttgcggc gtgacccgga gagctgttag
    11761 aaccgcctta gccggttcca ctgtggccag gaggtcccat gccccgtccg accagcgacg
    11821 tgcaagcatt cgaaacccac gcgaccgacg ccgacctcga cgatctgcgc gcgcggctgg
    11881 cggcggcgcg gctgccggag gccgagaccg tccgcggcgc ggcgcccggc cctcgccgat
    11941 gggaacaggg cgtccctctc gccgacctcg tcgatgtcgt gaactactgg cgcaccgagt
    12001 acgactggcg gtcgttcgaa gcgcgcctca accggatcgg ccagttccgc acgaccatcg
    12061 atgatctggg aatccacttc ctgcaccgac ggtccgcgcg cgcggacgcc actcctgtga
    12121 tcctgacgca cggctggccg ggcagcatcg ccgagttcac cgatgtggtg gacgaactgg
    12181 cggatccgaa agacgccgac gcgcccgcgt tccacgtcgt ggcgccgtcg ctgccgggct
    12241 tcggacacag cgacaagccg gccaccaccg ggtggggaac cgagaagatc gcggccgcct
    12301 gggtggaact gatgggaagg ctcggctacg acaagttcgc ggcccacggc ggcgactggg
    12361 gaggtgtgat caccaccgtc ctcggcggca ggttccccgc gcacgttctc ggcatccact
    12421 cgaccctcgc ccaggcacct cccggcctga cgacggacgg gctgacggcg ggcgagcgcg
    12481 agtggaccga tcagacccgc gatttctggc gccaccgtgc cgcgtacgcg aagcagcagg
    12541 cgacccggcc gcagaccatc ggctactcgc tcgtcgactc accggtcggg cttctcgcct
    12601 ggatcctcga caagttcgcc gagtggtcgg acaccgagga cagcccgttc gagctgattt
    12661 ccagggaccg tgttcttgac gacgtcaccc tgtactggct gacgcggacc ggcgcgtcgg
    12721 cggcccgtat ctactacgag agccaccact ccctgaaccc cgaactccgg gtggacgtgc
    12781 cgtcggcgat cagcatgtat ccccgcgaca tcgagaagtg tccgcgcccc tgggcacagg
    12841 agcggtaccg gcggatcgtc cgctggaggg agcccgaggt cgggggacac ttcccgtcgc
    12901 tggaggtccc cgggtacttc gtccgggatc tgcgggaggg cctcgcggcg gtgctggccg
    12961 cgaatcgctg aacgcggccg ggtggccggc cggtaccggg accgggacag cgtcccggtc
    13021 accggccgcc cggcccggcc cccgccggtt ctccctcagc gcttcctcag cgcttcctca
    13081 gcacagacag cccgtcccgc cggggcgcgg gtcctgccac ccgtaccggc gctcggtccg
    13141 cgcggacacc agggaccgct ccttcaaatt ggccgcggga gaccgcgtac ccgtggctct
    13201 gaagggctcc agcagcgagg acaccgtacg gaccgtgccg cccgtcacca ccgtccgtac
    13261 ggccgccgcc gcgtcgatgt cccgcagcgg atcgccctcc acgaagacca gatcggcgag
    13321 catgcccgct tcgagcatgc cgaggtcgct gtccatgccc atgcgccgca cggggttggc
    13381 ggtggcggtg cgcagcgcct cgtacggggt gaagccgccc cgcaccatcg cgcgcaggtt
    13441 ctggtgcagc gacagggcgg gatcgtccag cggggcgtcc gagcccgcga tgacgctgcc
    13501 gccgccgcgc tgtacgcgca gcagcatgtc gacgccgccc gccagcagcg cgcggttcag
    13561 cccggcgtcc gggccgccgg ccgcgtccgc cttggccacc aggaccgtgt agtcccacgg
    13621 cgggtagagc aggcgggtcc gttcgtcggt gaccagggaa cggtcgtcgg cgagcagcac
    13681 ggaggagttc atcagggtgg aggtgacggg catcgaggcg gccgtcagga cggcgatggc
    13741 gtcctcgtag gccctgccca gccgggtctg ggtctgcgag tagccgacgc ggttgccgcc
    13801 gcccgtgtgc tccatggcgt ccatgccgta cgccgcgtgc gggtaggcgt agtgcgaggt
    13861 gacgagcagc ccccgctcgt gcgcctggcg ggtgaccgcg cgctccagtg gggcctgcag
    13921 ccggatgtag gtcttgacga ggtcgtaact gagccgttcg gcgcgctcca tctccagccg
    13981 cagctggtcg gtgccgacca cgggacgggc gaagttccag aacacccgcg ccccgtccag
    14041 ggcgtcgccc gtaccgaaga agcgcggccc cacctgggcg cccgactcga tggcctccct
    14101 cgtctccacc atctggtagg ccggatcgcc gggtgacagc acggtggtga tgccgtacga
    14161 caggagcagg cgtcccgtgc ggtcgcccca ctgccggccg cgcaggtgcc agtgcagatg
    14221 ggcgtcgacc aggccgggca tcgcggtcag gcccgacagg tccacgacgg tgtcgccccg
    14281 gccctgtccc gcggggcgga ccgcggcgat ccggtcgccc ttgacgacga tgtcggcggc
    14341 gccgcgcagt tgctcggcgc gcccgtccca cacggcaccg gcgcggagta ccacggtgcg
    14401 ggccgtcgcc ggtctgcggt aggtgagggg gacgggcacg gtgcgcgggg tgccgccggt
    14461 gagcgggacg gtgcgcagcg tgccgttgct cagatagaag agacggccgt tcgtgtccac
    14521 ggagagggag tcggtgacct ccgtggtgat ctgctcgggt gcgccggtga tctgtccggt
    14581 gggatcgacg ggcacccgcc acgccgtact ctccatgacg aagacgaagt gcttgccgtc
    14641 cggggtccac acgggtccgt cgtcgccccg ggtggcgatc gaccggtggg cggccacggg
    14701 ctgggagcgg gtggcgccgg tggccaggtc gacggtgagg acttcgctca gcccggcccg
    14761 gttgcgcctg gagtagggct ggttggcggc gaccgcgagg tgggcgccgt ccggggacca
    14821 ggtggggcgg cccggctgga agattacggg cagcacctgg cgtacggcgc cggaggcgag
    14881 ttccagcacc caggtcgcgc cgttctcgtc ctggtaggcg atcttcgtgc cgtccgggga
    14941 ccagcggggg gtgagctgcg cgcccggcag cgaggtcagc cgtaccggct caccgccggt
    15001 gaggtcccgg cgccacagtg cggccgttcc cgagcggtcg ctcgcgtgga cgagggccgt
    15061 gccgtcgggg gaccagtcgg ggtcggagtt gaagaatccg tcgtcggcca gtctgacggg
    15121 ggcctcgccg gtcttcatca cccacagcgc gttcagggcc cggaaggcga cgcgctgccc
    15181 gtcgcgggag acgaccgggc tcgcgattcc cctggcctgc cgggccgccc gggaggtgaa
    15241 gtccctgacc cgcggcgtcc agggcttgcg ggtgaaggtg accgtcgcgg tgaagtccac
    15301 cgtccggggg gtgccgccgg ggcgcagccg ccggacgcgc ccgcctgccg tgtagagcag
    15361 gtcgccgtcc ggggtccagg atgtgcgcag ggcgtgcacg tcctcgccgg cggcggccac
    15421 ctggccgtcg atcatgacat cggcgcgggt ccccgtgaac tgtacgtagc tcacccggcg
    15481 cccgtccggg ctgggcgccg ggccgaagat cttcgctccg gcgctcgcgg tgatcagccg
    15541 ggtcctggtc ccggtcgcca cgtccacgga gtcgatggcc gcgtcgttca ccgtgcagac
    15601 gatcgtcctg ccgtccgccg accaggcggg ggtgccgtcc tcgtcggggc cggtggtgag
    15661 ctgcgtacgg acgccggtgg ccgggtcgag cagccacagg tcgttgctgc ccgaccggtc
    15721 ggaggtgaag acgatccggc tgccgtcggg cgcgtactgc ggctcgcggt tgtcgtagtc
    15781 gtcgtcggtc agccgggtga ggccggtgcc gtcgcgcttc accgaccaca gctggtaggc
    15841 gccgtcgcgg aaggactgga acacgacacg gctgccgtcc ggtgcccagt gcggctgggt
    15901 ggcgtcctgg agttcgccgg tgagccggac ggcggcgccg cccgcaccgg ggaccaccca
    15961 gacggcgctc agcacgtcga tggcgaggcc ggtgccgtcg ggagagaggg cggcggccat
    16021 gttggtgccc tcggagacgg tgacggtggc ggtacgaggc gcaccgccgg gccgctcggc
    16081 gggccgcccc tgctccgtgc cggccgcggc ggcccggccc gcgctcgtac ccgcggcggt
    16141 cagcgcgccg gcggtcaccg cgccgctcac ggccaggaca tgccgtctgc tcgggccggg
    16201 agcgggggcg gggttcgtga cgtccatcag gttctcgtgt ttcttcagga gggacatgct
    16261 gtcaggaggg acataccgcg tgcaggaagc gggccagccg ggcaacgcct tccttgatcg
    16321 cgtcggggtc caagtaacta caggccaggc ggagttggta gtccccgccg ctgcccagat
    16381 agaagtggga catcggagtc cacaacacgc cgaactcgcg ggcggaccgt tcgagcagcc
    16441 gctcgtccgc cggtacggga agccggaccc gtacgaagaa gccgccgcgc ggccggttcc
    16501 aggagacccc ggcgggcgcg ccggtgcccg gtccgagcgc gtggtccagc gcgtccagca
    16561 acagacgcag attgcgctgg tacagcgcgg ccttggcgct gacgaccgag gccagcgagc
    16621 cccggtgctc cagcaggatg ccgccgacga cggcctgggc gatgggcgag gtgttgaccg
    16681 tcaccatgct cttgagggtg gcgagttcgt cggcgagcag gccggtgcgg cccgacgcgt
    16741 cccgtacccg ctggtcggcg acgacgtaac cgacccgggc tcccggcatg cacaccttgg
    16801 cgaacgtgcc gagatgcacg acccgttcac caccgggcag cgccttcagc ggcgggagcg
    16861 cgcccggctg gtgcgcggtg aacgcgtacg cgttgtcctc cagcaggagg aagtcctcgc
    16921 gggcggcgac gtcgagcagc cggtggcggt ctgccaggga gaggaaaccg ccggacgggt
    16981 tggagaagtc cggcgcgacg tacagggccc ggatacggcg gcccgcctcg cgcgccgccc
    17041 ggcacacgtc gtccagctgg gcgaagtcga tcccgtcgtc ggtgtcgtcg accgggacga
    17101 ggtccacgcc gagcaggccg gccgccccgg acagaccgac gaagcacggg ttgacgacag
    17161 ccacgaggtc cgtgggctcg gcggcgagcg cgcgcagcgc cagcagcatc gcctcctggc
    17221 agccgaccgt gatcaccacg gactcgggcg gcacgtcgat gccctggtcg gtgcggagcg
    17281 cgcccgccac cagatcgccg atgagacccc ggctcggccc gtactggtag aggagccgtt
    17341 cggcctggtc gggcttgagt ccccggtcct cggtgagatg gcggagatag cggtcgatgt
    17401 gccgggggac gtcgatctgg tcgaagaagc tgatgtgcgg ggcgcccggt gcgaaggaga
    17461 gcgcgtcggg gaagcggccc atcacctcgt tgaggaagtt gatcgatccc atggcgggag
    17521 agcccaggga gctgtgcagg cgctcgcgcc gcaggacgac acctgccccg gcggtcaccg
    17581 gccggtctcc gcgccggcgt gcgtgtccgt cctcgtgccg gctgccgcgc cgggctctgt
    17641 gccggactcg gtgccggact cggtgccgga cttcggcgga tcggtggccg agggccccgt
    17701 ccccgaccgc gccgagaaac ggcccacctt gtccagcacg tcctcgccgt agagccgttc
    17761 ggcctggacc agcgagaact ccgccatgta cgcgcggaac acgtcgaccg gctcctccga
    17821 gacacgcagc atgcgccggt tggcgagtac ggcgggcgcc gccagctggg tcaccgcgtc
    17881 ctccaccgcc cggtccatcg ccttcgggtc gaccacctcg tcgatcagca gccgggcgtc
    17941 cggctcaccc gcccagatct tgcgtccgcc gagcaccgcc tggcgggcca cccggccgcc
    18001 ggtcagccgc gccagccgga agttcgccgc gccgggcacg atgccctcct gcgcggcggg
    18061 gaggctgaga taggagtcgg cggcggcgat caccttgtcc atcaccagca gcagctgggt
    18121 gccgccgccg atggcgaacg tctccaccgc cgccacccac ggcttctcca cgccgtgcgc
    18181 cgggaaggtg tccgggcgcc cgagcgtgga cagaccccgg tacatcttgc tgatgtagcc
    18241 gagttcgcgc tggagcagga agccggtgaa cgagatccgg ccgtggtgca gatcggccag
    18301 attgacgccc gcgctgaaga cccgccgccc ccggtagcgc gggtgggtca tcggcccgcc
    18361 tcgcagcacc cccaccctga tcccgtcgtc cagcagcacg aggtcgacgg ccacttcgag
    18421 ctgggcgatc aggtcgttgt cctcggcgtt gagacaggag tcgttgtgga aggtcacatg
    18481 gccgccgtcg ccctgccgct ccaccgtcac cttgcccagc tcggcccgtc cggtggcccg
    18541 gaagtccggc agcagcgcgt gtgcccgggg cgtcgggtcc cgcatcacgt cgaccagatg
    18601 cgcgcccgcg ccgggcagcc gcaggatctc ccggaagaag atgccctggt cgatctcccg
    18661 gccttccttg tccgcctgcg cgtggcgcag ctcctcggcc agctgggcgc cgtccgggac
    18721 gagcccgggg aagctctcgg ccgccgcgcc cgccagctcg gtcagcccga gccgtgcggt
    18781 acgtccttcg gtcagccggt cgtagaccgc cgccgcgtgc gcccgcagga aggcggcccg
    18841 cagctcgcgg caggcgcggt ggatcgccgc ggcccccagc tgctgctcct cggagcggtc
    18901 ggagcgcggc ggcagcgcgg ccagcggtgc ctcgcggtca cggatctcgg cggccagcgc
    18961 gaggccggcg gccgacagct caccgccgtc ggccggggcg gccgcggggg cggagacgga
    19021 tctgggggag cctgacgtcg acacgcggtt ccttcgaagg aggagggaca ggaggggcgt
    19081 gcggggtccc cgtccgggcg ggcggggagc cgcttcgtac cggtggtcag cgcgcctgcg
    19141 ccaacgagcc gtcggccggg gcctgttcgg ccgccgactg tccggccgtg gtacggcggc
    19201 gcaggcttcg gtcgcacgcg gccagatggg cgcccagggc ctcctcgtaa ctgagggtgg
    19261 cgtcgaacag cagcctgcgc cgaatcgacc actcgcggcc cggcacggcc gacagctcgc
    19321 ccgccaccag caccgcgcgg cgcagggccg cctcgccgcc gtccgccgtc tcgtccacca
    19381 ggtccagatc agcggcctgc tcaccgtcca gccaggggcg gcgcagcagc aggcggcgcg
    19441 cccgcgccgt gccgatctgc tgcgccagcc ggtgcagcgc cgtgctcggc caggcgccgt
    19501 cctcggcgcc cgggagccgc aggcgcgcgt cgccggccgc gatccggtag tcggcggtga
    19561 gcagcgcctc cagcgcgggg ccggtgcagg tgccctcaac gagcgcgagg gtcgggcgcc
    19621 ccgaggtctc cagccggcgc agtgcccgct cccaggtgtt gaccagatgg atgcccgtac
    19681 cgacggggga cgcgccctcc gcggcgccgg cgccgcccag caggagcagg acgacaccgc
    19741 ggtcggcgcc ctccgccttc tcggcggcgg tgcgcacgcg gtcgaccagc gccggggtca
    19801 gttcctcgtc gccgaccgtc aggacggcgg ctgcctcgtc gtggagacgg acggtcaggg
    19861 cgttgggggt atcggtatcc gtgccggaca cggtcacact tccttcgtcg tccgccggtg
    19921 agggcggtga gggtggtggg ggcagtgggg atgattcggt gggtgccgtg ggtgcggtcg
    19981 gtgtcatggc gcgggtgccg tcaccactgg aggagcgccg tctcgatggt ggagccgggg
    20041 cccatggtca tgagcacgcc gtagtcaccg cgccgcaccc ggccctcctc catcaggcgc
    20101 tcgtaggaga acaggaacga gccgctcgac aggtttccgt agtcgcgcag caccccggtg
    20161 gtgtggcgca gtgcgtacgt actgaggccg aggttgacct tcaccgagtc gatgaccttc
    20221 ttgccgcccg agtggaccag ccagtggtcg atgtccgcgc gttccagacc ggtgccgccg
    20281 agcagccggt cgaccacctc ctcggcgttc gccccgacga catacggcac gtcacggtcg
    20341 aggaagaagc tgaacttgcc ctggtcgtcg tcccagtcgt agcgcatcgc gtccaccgct
    20401 tcggggatga tgcggctggc ggccttcagt acggtgccca cgggcgccgc ctcgtcggcc
    20461 tccgccgtct ttgtcgcgtg cgcgccgtgc gccgcgcgtg ccgttcccgc cgggtcggtg
    20521 accatcacga cggccgccgc gccgtcgccg aagaggctgt tcaccaccga ggtgcgcatg
    20581 gtgccgtcga agacataggc ggcggagcag acctccgcgc agaccatgac ggccgcctgc
    20641 ccggggttgg ccgccgacca ggacgcgacg gcggccatgg cgttgaggcc ggcgttgcag
    20701 cccatgccca cgacgtcgag ccggccggtg gagaccggca gccccgcttc cttgacgaga
    20761 tgggcggaga aaccgggtgt gagcagcccc gtggtggtca cacagcacag gtatccgaca
    20821 tcggagagcg cgaggccggc ccgcttcagg gccgtctcca gcgcctccct gcccgtcctg
    20881 acgccctgct ccttgtgctt ggcgagcagt tcgccctggg tctcggtctt gcgtgtgccg
    20941 tcggccagtt cgggcggcag ggtcagatag cggcgctcga tggcgctgtt gaggaagacg
    21001 gacctgatcc gggggtcctc gatgccgaac agctccagca tctcgcgctg tgtgtaggag
    21061 ttggcggggg tggccgtacc gaagccgaca accgatggcc ggggccccgc gttcgccgtg
    21121 ctgagccgct gtccgggcgc ccgggtcgcg ggctcggtgg ggacggcggc ggaggccggg
    21181 gccgtgggtt ctgtggcggt catgccggca cctccagctc gttggtggcc agctcgatct
    21241 gctcggtggt gtgcgccgcc gagacggcca tccggatcag accgctgccc ttggccacgg
    21301 tcgggaagaa cgcgggggtg acgatgacac ccgccttgcg cagccgcgcc gcggtcacca
    21361 gcgcgtcctc ctcgctcttg aagagcgccc cgcggatcgg cgaccgggtg cccgcgttga
    21421 acagcgcgcc tcccgtgcgg gagtcgaaga gttcggtgtt gcgccacaga tcccgctgga
    21481 gccgcgcgac cgtaccgtcg agatgcagct ccgccgacgc ccggcaggcg ctgatgacgg
    21541 gcagcgcgat ggggccgccg aagatcagcg ggttgccgaa tcttcgcagc tcgaccgtgt
    21601 cctcctcggt gttcagcagg acgaagccgc cgttgctgcc gccgaacgcc ttggcgagcg
    21661 agccgacgag gatcaccgag gcgggcagcc cgcccggcag atggcggaac tcctcgtacg
    21721 cgaaacccgc cccctgttca ccggtgatcg acacaccgtg cgcgtcgtcc acgtacagat
    21781 agccctcggc cgccgcgcac aggtcgtaca gcgcggccac gtcgatgagc ccgcccatgg
    21841 accccacgcc gtccacgagg acgatcggcg tgcgcccggc gtcgcgcacc gccgccagcc
    21901 ggacggcgag gtcgtccagg tcctcacagt cgaaccggtc cacgtcgccg atctgttcga
    21961 gcacgccgcg caggacctgg atggacgcgt gcgcggtgcg ctcgatcagg aaggtgaccc
    22021 cgctcgccga caccgggtag ctgggcagca cacccgttcc cagcagcggc agcaccccca
    22081 ggtggacgct gccgacggcc gtgaagcacg tggcgtgccg gccgccgtag atgacgccga
    22141 gcatccgctc cagcgattcg aggtcctcgt accgcatccg ggtgcgtgac gaggagaact
    22201 ggacgccgac ccggcgcagg ctggcgacgg ccgcctccac cagggccggg tgggtgtcga
    22261 ggcccagata ggagcaggag atgaactcga cggcgctgcg gccgtcggcg agcgtcacct
    22321 ccttcccctc ccgcccggtg aagacatggc tggtcaggtc ggtggcgatg gcccgggtca
    22381 gcgcgtccga cgtcttgtct acgcgcgtgg ctacccagtt gtgtcgttcg atcgtacgag
    22441 gcatcggagt gtctccaggg atgcgtacgg atgcgtgaga aggagcggtc ggagcggtgg
    22501 tctcggcggc gcggaaatct cgcgggagcc gcgtgacgga cgtgcggcgg aagggagttc
    22561 agccggcggt gcggttgacg aagaagggtg tcttgccccg tgccgtgtgg tggaactcgg
    22621 agctgtcgac ccgctccagc gtcagcccgc ggtacagcgg cgcggtgaag accctcccca
    22681 tgtggtaggc gccgtgcagc gcggcgacgg cgtcctcggt cgtgaccgag ggcggcgtac
    22741 gttccgagac cagcagccgg atcgagaagc ccggatcgtg ctgggtcacc tggaactggc
    22801 agtcggccgg gtcgctgatg cccagcgtgg ccagctgctc catcaccaga tcacgggaga
    22861 tggtggtgct gtcgacattc atggacatgc ccacccggcc cgtgagggtc agctgccgcg
    22921 cggcgctgcc gcacagacag gggcgggtct cgatgaatcc ctcgtcgccg atccggtagc
    22981 gcagcagcgg cataccggag tcggtgagca tcgtgacgac cacctcgccg atccggccgt
    23041 cgggctgtat ccgctcggcg tccgtgtcga ccacctcgac caccagcacg tcctcgtgca
    23101 gatggtgggt cgaaccgctc tggtaggtgc actggtagcc gaccggcccg gtctcgctgg
    23161 tggagtacga gaacgaccgc acccgcagat cgggccgggc gtccgcgagt tgacgctccc
    23221 ggctctcacc gaggatctcc ccgatgtaca gcagactgtc cacaccgcgc aggagttcac
    23281 gtgtcgcgtc gccggtcagc agccccgtcc ccgccgaggg tgagcagacg accgcgtcca
    23341 cctggttctc gcggagcagc tgagccgtct ccggggaggc gagggcgctg ctgcccatgg
    23401 ggaaggacat ggccggcagc agctccgtga cctcctgggc gaaggtgaac gcgccgttca
    23461 gctcgcccgg gtagaggaag ttggcgatac ggcggggatg cggtcgcagc gcgctgcgca
    23521 ccccgcgcgc gccgagagcc gacacccggc ggctgaactc ccacgagtgg tagatcatct
    23581 tgcgccgtcc cgatgtaccg ctggagcgca ggacgagccc ggagcggccg tcgccgagca
    23641 ccagattctc cgaggcgggc ggacaggacg cctggagatc ggccggtgag aacaggggga
    23701 gtttgagcag atcgcgcggc acccgcacgt cgagcgcgcc gggccagcag gcggccaccg
    23761 ccggattcct cttcagggcc tccaccgtgc gggcgagatt gcgctgctgc atttcctcga
    23821 gctgcgcccg cgtcagaatg tcgagattct ctgccagttc aatctttgac gactcaccgg
    23881 cacgcgcctc gctgtggtgc gaggtcggat acatttcccc cagcacgatt tcctcacttg
    23941 gtccactgtt caacagattc acctgtccgc accactcgac cgaggcatgc ttttcggcca
    24001 ttgcgtcgct gtcgccgggc tggaaatagt taaattccga ttgcttccgc atatgccccg
    24061 acgcgcccgt cacggcggta cgttcgctgc cgcgggccga ttccccttcc ggtccgcggt
    24121 cccgtatccg ggccactccg gcgggcggcg gccgttgaac gcggcgacgc cctccgccca
    24181 gtcggccgag aaggcgaccg tgtgccaggc ggcgtcctcg acttcgagcc ccgccgccag
    24241 atcccggccc tgccccagtc gcagcgcgcg cttggcggca cgcagcgcca caggcgagtt
    24301 ggccgcgtag gtacgcgcga ggtcgagagc cgtggcgcgg accgcgccgg cgggcgcgag
    24361 gacgtccacc agcccgaggt cgcgtgcctc ggtggccggt acccgtcgcc cgctgaagat
    24421 cagctgggcc gcgacggccg ccccgaccct gcggggcagc aactgcgtac cgccgccgcc
    24481 cggaatgacc ccgaccgtgg tctcgggcag ccccacggtc gcgccggggt ccgccacgat
    24541 gacgtcgcag gacagcgcga tctcgtaacc accgcccagc gcgtagccct gaacagcggc
    24601 gacgaccggc atgggcagcg ccagtacgcc cgcgtacgcc gcccggctgc ccggccgcgc
    24661 cgcggcccgg tcggcctcgg tgtagccggc acgttccttg agatcggcac ccacgcagaa
    24721 ggcgcgttca cagcgggagg tgatgacggt gacgccgacg gagaggtcat gtccgagatc
    24781 agccgtcgcg tcggccagcg cggcgccgaa gtcggcggaa accgcgttca tgcgttctgg
    24841 ccgattcagg accagttcgg cgatccggcc gttgtgtgtg cggtgaacga gaatgtactc
    24901 tccgtagcgc agttcggaca tcacgccctg cccggtccgg gatcagggcc gatgtccgcc
    24961 atcgacggtg agcacaccgc cccacggtga atttcggcca cggtcgaata tgacacggct
    25021 ggacatgtga ttgcgcgcag cacgactcgc ttctcccccg acgtaatcag tgcctgatac
    25081 gacgtaaatc tgccatctgc cgagaggggg ccgccagtgc gcatgcacgt cgtaatgccg
    25141 ccaggcgaga atgcgacggg ccgaaaaccc gccaaattgc ctgaacggat taatctggaa
    25201 ttttcggaca tgaggtagtg cagtgaatat gccagctcac catgttgatc gctccccgct
    25261 cccgatagac gaggagatca cctcggccta cgcattcctc tgcggttcgg ggaacgcgtc
    25321 cgtcgaacag atcgccgccg cgctggaaat cggaatcgaa cgagcgcggc aattggtcgg
    25381 ccgcctcacg gagttacatc tgatcgattc cgccggggac ggcacgtaca caccgggatc
    25441 gccccgggcg ctcggcgccg gcgtcatcgc ccccgccatc agggagctgg agagcggcca
    25501 gcagcagatc atcaggatga tgacggagct ggacgccctc accaagatct acgagcggag
    25561 tccagccgag cggctgcgcc gtccccggat cgagatcctg cccgaggtca ccgccgtacg
    25621 ggcggtcctg accgaactct cggcaggggc tcggacggag atcctcacct cccagccggg
    25681 cggcgcccgc cccgccgatg tgctgcgcga gtccctcgaa cggacggaag cggtgctgag
    25741 ccgcggcatc accatgcgca ccgtctacca gtacaccgcc cagttctcac aggtcacggt
    25801 ggactacgtc cgccatgtga cggagcgggg cgtcgaagtg cgcatgctcg gcgacgcctt
    25861 gatgcggatg atcatcttcg accgggagat cgccgtcctg ccgcagtacg accgggacgg
    25921 tgccgtggtc gtcagcgacc ggagcatcgt ggacttcgcc gtgcaggcgt tcgaacgcgc
    25981 ctggccggtg gcgaggccgt tccccgtctc gtacgaccgg ggccaggtca agagcacctc
    26041 ggtcgaaatc cagctctcca tctcacggtt gctggtggaa gggctggagg acaaggtgat
    26101 cgcccgccgc atgggcatgt cgctgcggac ctgccagcgc cacatctcgg agatcatgtc
    26161 gcgcatcggg gcccgcaacc ggatgcacgc gggctatctc ctggggaagc tgatcgacag
    26221 tcagaactga ccgggcaccg gagctccacg ctcaggacag gtcccgggcg gacgaggctc
    26281 cgggcgaggc gtccggcgag tcgtcgggtg agccgtccgg ggaaccatcg gcggaaccgc
    26341 cgggcgcgac ctcgcgcgtg gccttggcag cgcccgaggg cacgacgtac cgggtgacgg
    26401 cgagaccgcc cacgagcagc accagccccg ccagcacacc cacccccatg ccgaagtggg
    26461 ccggctgcgg cagccaggac gcggaggtgc tgaccgcgag cccggccgcc atgttcccgc
    26521 agatctcacc gatggccgtg accaggctga cgaggccgat gacatccgtc agccgtgtct
    26581 gcggcaccgt gtccgccgcc tccacctgga tcttcgggaa ggccaggcac tccgcgacgg
    26641 cgaacagcgt cagccccgcg aggatgagcg tcagactgcc gctgaaggag agcacgagcc
    26701 ccgtgccccc gcccaccgcg acgatcagat acagcgcgcg gcgcctcagc cgggtgaaga
    26761 acggcaggag cgccagctgg atggcgatga tcgccagcgg ctggaagctg aggaacagcg
    26821 tccggtgctc cgcctgggcg gggttgacca cctcgtacag caggatcatc gcgtagagga
    26881 accccatcgc gaagtagatc gcgaaggtgt agccgagcac caccgccacc gcgggcgtcc
    26941 tgaggacggt gagccgtccg cgcagcccgt tcgcaccccg gggcggcagc gcgaagtcga
    27001 gcccccgggc gaggagtccg acggtgatcc cgatcaccgt ctcgacgacg gccaggacga
    27061 gcagcgcggg aaccccggcc cgtccgaccg gccccgccgc gagcggcgcc agcacatagg
    27121 cggtgttcag caggatgaag aagacctgga agacctggct gcggcggtcg tcggtcgccg
    27181 cggcgaccaa cagggaacgc accgcggggc gtgagatgcc cacgccgaga ccggccagca
    27241 ccgcgaagag atacagcgcc ggagccgagg tgctgacggc gacggtgacg aatccggcgg
    27301 ccttcagcga cgaggcgatc gtcaggaccc aggccggatg gacccggctg aacgcgatcg
    27361 gcgtgaccag cgcgccgacc agggccgagc cgacatgcac ggacagcgcg aaggagaaga
    27421 cggacggctc gatccgcccg ccgtgcagga ccgccaccgg aagcagcgtg agcaccatcg
    27481 ccagaccgaa gttggacagc agggtgaaac ccagccccgc tcccacggcc cgggggtacc
    27541 agcccgcctt cggcgtgccc gtctcggtgg ccgttcccgt catgcgctgt gcgccggggc
    27601 gggctcggac agcagccggc cgacccacgg gaagaacgcg tcggccaact gcgaccgggc
    27661 gggctcgggc atcgaggaga actccgccat ggcggtgccc cactcgccga gcaccggccc
    27721 gtcgtcggtc agcagccagt ccacacagag atatccggcc tggagatccg cgacgatccg
    27781 ctccacgtca ccgagcacgg tcgccacgtc cgggttggcg ctcgaactgc cgccctgggt
    27841 gatgttggcg aggtacgcgc cctccgccgg gctgcgcagc atgctcgcgg cgaacttccc
    27901 gtcgaccatc gccacccgca gatcaccctt gttgggcagg tactcctgca cgatgtagct
    27961 ctgcccggtc tgggacgcga tgtcgacggc ggcccgcaac tgctcgtagc tgtccagctt
    28021 cagcacaccg aagccgatgc ccatctcgcg cgccttgagg atgtacggcc cctcgccgat
    28081 ctccttgcgg acgacgtcga gccccttgcg cgcgtagcgc ccgaagggca gcgccaccgt
    28141 cttcggcacc cgcaccccga gcgtcgacgc acgggccagg atcgccagct tgtcgcgctc
    28201 caggcattcc ggccccacga gcgagcggtt gagcaggacg gagtcgctgg cgtcgatggc
    28261 ccggtagatg ccccgcagga aatgagtggc ctgcgggtcg ccgctcacat cgtccacgat
    28321 gtacgcctgc cgcgtccgga gcagatccac cccgtcgtgc cacagccggg ggcgctcgtc
    28381 gcacgcgggc acgagctcgt tcgcgctgat gaaccggaag gcgaatccgt gcctcgcgca
    28441 gggctccgcc cagcgctccg tcatctgctc ggtgatcttg tccacatact ccggcagaaa
    28501 gtcgtccgga tggcagatcc acgtcaccag gcgctcattc gccacgatcg caactcctac
    28561 gagagacctc atcggcatgt gacggcaccc ccgcgaccca ctccgaccgc tgcaccgacg
    28621 acgtctcact ctttcaggat tccggccggc ctcccgtccc tccgggggct cggatcttcg
    28681 ccttgcgccg atgcgacagg ggtgcggggc ggccggcctc gcgacgggcc tcaggccgtg
    28741 cgccgcagca gcgccagata catcgcgtcc gtgccgtgga catgcggcca cagctggacg
    28801 tcggggccct cccccagcgc tgcgacgccg ggcatcagcg gccgggcgtc gacccattcg
    28861 gcctcggcgg cggggccgcc cctgcccttg agcacgtcct cgaccacgac gcgcgtctcg
    28921 gccaggtgcg gggagcacgt ggcgtagccg accactccgc ccacccgcac ggccttcagc
    28981 gcctcgcgca gcagtgaccg ctggagtggc gcgaagccct ccaggtcctc gggacgacgg
    29041 cgccagcgcg cctcggggcg gcggcgcagg gcgccgaggc cggtgcacgg gacgtcgacc
    29101 aggacgcggt cgaagactcc gggccgccac ggcgggcggg tgccgtcggc ggtgatcacc
    29161 tggtacgggc cggggttgcc cgcgagcgcg cgctcgacca ggcgcgcgcg gtgcggctgc
    29221 ttctcggagg cgagcagccg cgcgccccgc tcggcggcca gcgcggccag cagcgccgct
    29281 ttgccgccgg ggcccgcgca gccgtcgagc caccggctgt cggtgccttc cagcggcgcg
    29341 ttggcgagcg ccacggcgac gagctggctg ccctcgtcct ggactccggc ccggccttcg
    29401 cgtacggcgt cgatggcgcc cggttcgccg ccctcggtga gccggaccgc gtacggggac
    29461 cagcgtcccg gcagtccgga ctcctcgccc agtgtgtcga ggagtgcgtc ggccgagacc
    29521 cgtccggggc gcgcgacgag cgtcacctcc gggcgttcgt tgtctgcttc gagcaggtcc
    29581 tcgatgccgg cccggccgcc cccgagcgcg tcccagagcg cggagacgat ccagcgggga
    29641 tgggagtgga cgacggcgag gtggtcctcg gcgtcctcgt cgtacggcgg tgcgacccgc
    29701 tccacccagg cgtcgaggcc gtccttggag atcttccgca gcacggcgtt gacgaacttc
    29761 gcgcggccgt cgccgagcac gacgcgggcg agctccacac tcgccgacac ggcggcgtgc
    29821 gtggggatcc gggtgccgag caactggtgc gcgccgaggg ccagtacgtc gagcactggc
    29881 gggtcgacct ggcgcagcgg gcggtcgatg caggcggaga tgatcgcgtc gtacgtgccc
    29941 tggcggcgga gcgtgccgta gaccagttcg gtcgcgagcg ccgcgtcgcg gttgtcgaag
    30001 tcacccgcct ccctggcctt cttgaggagg ggcgggagga cgaggttggc gtaggcggcg
    30061 cgttcgtcga cggcccgcaa cgcctcgaag gcgaggatcc gcacgggatc cttcttggga
    30121 cggcggtagg tcttggaggg acggcgacgt gcctgctcgt tcaaaggtgc tccgcagttg
    30181 aaaaggtgct ccgcaacagt gccgcgcgtg agggtgccgt ggtaccgcgc gtggcggtgg
    30241 gacaccctca gcgtacgtcc gcggccccct ctgccgcgcc gagccgctca ccgggcgcga
    30301 tccgcacgcc gcgggcccag tcggcggccc tcatgggctt cttgccctgc ggctggaccc
    30361 agagcagctc gacggcgtac gagccggtgc cgacgtgcac ggagttcttg ccgacggccg
    30421 gctccccggg cgcgaggtcg gtgcggtcgg gcaccggctt gagctggatc agcttcaggc
    30481 gttcgccgcg gaagacggtc caggcgccgg gcgcgggggt gcagccgcgt acgacacggt
    30541 cgacacgcag cgcgggcgcc gcccagtcga cacgcgcgtc ctcgacggtg agcttgggcg
    30601 cgagcgagat gccttcggtg ggctgctgta cggccttgag ggtgccgtcc tcgatgccgt
    30661 ccatggtcgc ggcgagcagt ccggcaccgg cgaacgcgag cctggtcagc aggtcaccgc
    30721 tggtgtcggt gggccgtacg tcctcggtga tcacgccgta caccggtccc gagtccagcc
    30781 cttcctcgat gaggaaggtc gccgcgccgg tcgtctcgtc cccggcgatc accgcgtgct
    30841 gcacgggcgc ggcgccacgc cacgcgggca gcagcgagaa gtgcaggttg acccagccgt
    30901 tggccgggat gtcgagggcg acgcggggca gcagcgcccc gtaggcgacg accgggcagc
    30961 agtcgggggc gatctcgcgc agccgggtca ggaaggcctc gtcacggggc ctggcgggcc
    31021 ggaggatctc gatgccctcc tcttcggcgc gctgcgcgac ggggctggcg acgagcctgc
    31081 ggccacggcc ggcgggcgcg tcggggcggg tgacgacggc ggcgacctcg tgccggtcgg
    31141 aggcgatcag tgcgtccagg gctggtacgg cgacctcggg ggtgcctgcg aagacgagct
    31201 tcactgcggg acttcctcgc tctctcgtgc ggcttccggt cggtcgtcgg cgggcgggcg
    31261 gcgggcaccg gcgcggccga cgacggacag cgcaccagtc tatgggccgc ccggggccgg
    31321 ggcggcaggg ggcgtacggg agcccgcgcg ccccaggcat atgcgcatac gcccccgcag
    31381 cgtgaccaca acggcgggtg gcgcgttgtc aagggagatt gacctcaaac gggccgcccg
    31441 gtgcggcccg atccgtttca acgccggttc gagaggcttg ttaatggccg accacgcaac
    31501 ccacgacgca caagcccggg caaacctgca cctgttggtg cgggacatcg agcgcgtccg
    31561 ccggcaggtg gacgcactgc gcaccctcac agcccagttg ggcaacgtct accgcccgcg
    31621 ccgttcaggc ccttcgacgg gcttcgtcgt ctacggccgg gcgccggccc cgaccgtccg
    31681 tctcgcgcag gaactgcggg acagtgtcga gagtctggtg acggcggccg tggatttcga
    31741 tcgctcgctg ggcttctcgt gggacgcggt cggctcggcg ctcggtgtca ccaagcaggc
    31801 ggtacaccgc cgttacggta cgagacgcgc ggcccagcag tcggcccccg ccgagggcga
    31861 gcgcccggcg gactccgcac agccccgccc gtcggggccc gcgcagggcg tcccggcggt
    31921 gcccgctgcc cggtcgatgc cgccgcagcc gacggtggcg ccgcagccgc tccgcgaaga
    31981 ggcacgcccg ggggcgttcc cgggtccacg caacggctga cgaggccgct gcccgatcgc
    32041 agggacgggt cggccgcggg tgcggcccac ccgccggccg gggaggccgg gacgggcggg
    32101 caaccacccg tccgtcgccg acggtcgggc caccacccgg ctgccggggg tgggtcgggc
    32161 gccccgtcag ccgatgtcgg ggggatcgat ccggatacgc accgggtcgc cgccgccccg
    32221 tgccagccgg cccgcctggg ccgacttcag ggccgtcgcc agcgccgcgc cgctgcccgg
    32281 cggcacgcgc agcagcgcgc gctcccacac ctcgcccggc ggctgatcgc cggtcctgcg
    32341 gggccgggcc gggtccgtga ccggcagcgg gaccgggccc aggacctcgg cgtcgggcgg
    32401 cagttcggcg gcggccagga acgcggcgac cgcgtcgggc ccgccggtca ccgccgccat
    32461 ccgcgagacc ggcgggaagc ccagctccgc ccgctccgcc agctcgcgct gggcgtggcc
    32521 cacgggatcc cagcgcacga gcgcctgcac gggccgcagc gtgggctcgg ccacgaccac
    32581 gaccgtgccg ccgtcggcct ggccccggac cagcgaagcg gcgtgcagcc agcgccgcag
    32641 cgcctcctcc cccgccctca gatcgggccg gccgagcatc gcccagccgt cgaggagcag
    32701 cgccgccgcg tagccgcctt cggcgacggg ctcggcgccg ggcgtgctca ccaccagcgc
    32761 ggggcggccg ggcaccgtgt cgaggatgtg gtcgcggccc gacgtacgca ccgggaccgc
    32821 cgggaacgcc cggcccagct cctccgccgt acgccgcgcg cccacgacgc tggcgcgcag
    32881 ccgcgtacca ccgcactccg cgcagcgcca ggcgggctcg ccgcgtccgc accatccgca
    32941 gtgcaactcc cgctgttcgg gggcctccag ggggccggcg cagtggcggc agcgggcggg
    33001 cgcacggcag cgctcgcagc cgagccgggg cacatagccg cgccggggga cctgcacgag
    33061 gaccgggccg gtcctgagcc cttcccggac cgcctgccag gcgaggctgg gcagccgggc
    33121 cgcgcgggcg gcctcgtcgc gcgccagctc gccgtccccc accgtccgga tcaggggcgc
    33181 ggccgtacgg aaccgctccc ggtcggccgt catcggcaac gcccagcccg tctcgaccag
    33241 ttgggccgcc tcgacggtgc agcccgtact gcccaggagg aaggcgcact tgtcgtgcgc
    33301 ggcgcgcagc agcaggacct cgcgggcgtg cggcagtggc gcgtggagtt cgctgtggct
    33361 ggagtcgccg tcgtcccaga tggcgacgag cccgagatcg cgcacgggag cgaacatggc
    33421 cgcgcgggtc cccacgacgg cccgcaccgc gccgcgtcgg acggcgagcc actggccgta
    33481 ccgcttctgc gggcccgcct ccgcggtgag cagcgcgtgg tggccctcgc cgagcagggc
    33541 ggtgagcgcg gtgtcgacgc gcgccgccgc gcggccgtcc gggacgacga cgagcgcgcc
    33601 gcgccccgac gcgagggtcg ccgtgacggc ccgcgccagc tcctgcgccc agtggggtcc
    33661 gggcagcgcg gtccatacgg ccctcgggga gccgccgtcg gcgagcgcgt ccagaaaagc
    33721 cgcgcctttc gcgtaccgct cccaggtgcc cgtctccggc ctgccgggcg cgggcagcgg
    33781 atcgggcgag ggtctggcct ccgcgcgcgc gttcctcggt ggcacggcca gttgcaggac
    33841 gtcggcgagg ctgcccgcgt aacggtcggc gacggcccgc gcgagcccca gcagctcggg
    33901 gctgagcacc ggctccgggg acaccacacc ggccagtgcc gcgagcggtc cggtgtagtc
    33961 cgactcggcc cgccgctcga cgacgaaccc gtcgatcagc cgcccgccct cacggcgccc
    34021 gccccgcacc tgatgcgccc cggccccgaa ccgcacccgc acccggacgc ccggctgcgc
    34081 ggcctcgtcc agctcctcgg gcacggcgta gtcgaagaac tggtcgagat gcagcacccc
    34141 tttgttcacc acgacgcgag ccacgggcaa ctccgccgcc aatggcgccc cccgccaggt
    34201 ccggggcttg gcgcggggca ccttggcggc ccgcacggtc tcccgaatga acgcgagctg
    34261 ctccggccca ccgcccccgg cggactcctc ggactgctcg tcgtcgctgc tcacagccaa
    34321 attcttacca gacggcaccg acagccgcgg acggtccggg gccgaccgat cccgcccccg
    34381 tgatacgccg acgggccccg gacaccatcg gtgtccgggg cccgtcggcg ctgacgtacg
    34441 cggaacgcct tccttacaga cccgccgcct cgcgcagcgc gtccacgcgg tccgtgcgct
    34501 cccaggtgaa gtccggctcg tcgcggccga agtggccgta cgccgccgtc tgggcgtaga
    34561 tcgggcggag caggtccagg tcgcggatga tcgcggccgg gcggaggtcg aagaccgtgg
    34621 cgatggcctg ttcgatcttc tcgacgtcga ccgaggccgt gccgaaggtc tcgacgaaca
    34681 ggcccaccgg ctcggccttg ccgatcgcgt acgcgacctg cacctcgcag cgcgaggcga
    34741 ggcccgcggc gaccacgttc ttggcgaccc agcgcatggc gtacgccgcc gagcggtcca
    34801 ccttggacgg gtccttgccg gagaaggcgc cgccgccgtg gcgggccatg ccgccgtagg
    34861 tgtcgatgat gatcttgcgg ccggtgaggc cggcgtcgcc catggggccg ccgatctcga
    34921 agcgtccggt cgggttgacc agcaggcggt agccctcggt ctccagcttg atgccgtcct
    34981 cgaggagctg cttgatgacg tgctcgacga cgaactcgcg gatgtcgggt gccaggagcg
    35041 agtccaggtc gatgtccgag gcgtgctgcg aggagacgac gaccgtgtcg aggcggacgg
    35101 ccttgtcgcc gtcgtactcg atggtgacct gggtcttgcc gtcgggacgc aggtacggga
    35161 tggtcccgtt cttgcggacc tcggagagcc ggcgcgagag ccggtgggcg aggtggatcg
    35221 ggagcggcat cagctcgggc gtctcgtcgc aggcgtagcc gaacatcagg ccctggtcgc
    35281 cggcgccctg cttgtcgagc tcgtcgccct ctccttcgac ccgcttctcg tacgcggtgt
    35341 cgacaccctg ggcgatgtcg ggcgactggg cgccgatgga gaccgagacg ccgcaggagg
    35401 cgccgtcgaa gcccttcttc gacgagtcgt agccgatctc caggaccttg tcccggacca
    35461 gcttcgcgat cggcgcgtag gccttggtgg tgacctcgcc ggccacgtgg accaggcctg
    35521 tcgtgatcag ggtctcgacg gcgacccgcg aggtggggtc ctcccgcagg agcgcgtcga
    35581 gaatggtgtc gctgatctgg tcagcgatct tgtcagggtg accttcggtc acagactccg
    35641 aagtgaacag acggcgcgac acatcgctcc ctggggttgc agcggctgct ggctagatcc
    35701 ttggcggaag tggcggggag ctgcgccccg cgtcgttccg gggccagttt atccggcaga
    35761 cgccgagaaa ggtccaggcg tctcggccag tgggagtgga gttaggggtt gtcactccgt
    35821 cctgcgatac gacgatcacc cactatcccg accccaaaca ttgggtttgg gccgatttca
    35881 cacgcccgga agggcgaacg aagaattaac tctccgttcg tctacgcgga cccgagcgcc
    35941 ggtacgacca ggtcccagac ggtgtcggcg agcgcctcct tgggaccgta cggaacgggc
    36001 gtctcgccgc cgtccgcggc gaggatcacc gcttcgttct cctcggcccc gaaggtcttg
    36061 cgctccccca cctcgttgac gaccagcagg tcgcagccct tgcggcgcag cttcgcccgg
    36121 ccgttggcga ggacgtcgtc cgtctcggcg gcgaagccga cgatcacctg tccgggcctg
    36181 gcgcgctcgg cgccgatctc cgcgaggatg tccgggttgc ggacgagcac gatcggcgcc
    36241 ggctcctcgc cgtccttctt cttgatcttg ccctcggcgt aggatgccgg gcggaaatcg
    36301 gccaccgcgg cggccatgac cacggcgtcg gcgtcggcgg ctgatttcag taccgcttca
    36361 cgcagttgta cggcggttcc gacgcgtacc acgtcgacgc ccgccgggtc cggcagcccg
    36421 gtgttcgcct cgatgagggt gacccgggcg ccgcgggccg ccgccgtacg ggccagggcg
    36481 tacccctgct tccccgagga gcggttgccg aggaagcgca ccgggtcgag cggctcgcgc
    36541 gtcccgccgg ccgagacgac gacatgccgc cccgccaggt cgggcgtgct cacgccgcgc
    36601 gccagcagcc ggcggcagac ctcgaagatc gcgccggggt cgggcagccg ccccttgccg
    36661 gtgtcgacgc cggtgaggcg gccgacggcg ggctcgatga cgaccgctcc gcgctcgcgc
    36721 agggtcgcga cgttcgcccg ggtcgcgggg tgctcccaca tctcggtgtg catggccggc
    36781 gcgaagacca ccgggcagcg tgcggtgagg agcgtgttgg tcagcaggtc gtcggccagg
    36841 ccctgggcgg ccttggcgag caggtcggcg gtggcggggg cgacgacgac gaggtcggcg
    36901 gactgcccga tgcgcacgtg cggcacctcg tggacgtccg accagacctc ggtggagacg
    36961 gggtggccgg agagcgcgga ccaggtcgcg gctccgacga agtgcagggc ggacgcggtc
    37021 ggcacgaccc gtacgtcatg gcccgactcg gtgaggcggc gcagcagctc gcacgccttg
    37081 tacccggcga tcccgccgct cactcccagg acgaccccgg gcccgccccc gcccggccgc
    37141 cccggctcct gcgaccgctc cgtccggccc acctggtcca cctggtccac cgtgtctccc
    37201 cgcgttcgga tggattcgtc tcccccatga cacaccacgg gcccggcagt cgcgctgccg
    37261 ggcccgtggt gagaggaatt gttcgccgtt actgcgccgg gccgtcgatg gcctcggacg
    37321 tcagcagacc cgcgttgatc tcacgcaggg cgatcgagag cggcttctcg tggacgtgcg
    37381 tgtccaccag cggaccgacg tactcgagca ggccctcgcc gagctgcgag tagtacgcgt
    37441 tgatctgacg cgcgcgcttg gccgcgtaga tcacgaggct gtacttcgag tccgtggcct
    37501 cgagcagctc gtcgatcggc gggttgatga tgccctcggg cgtggaaatg gaagaggaca
    37561 ctctcttgcc ttccgaagaa aaaacaggga aatacaggaa ataccgggtg ttgccgacgt
    37621 ctgcgcgaca agcagacagg ggtcagacaa ctgccatcaa ggctagcagc tcgcgcgcca
    37681 cgtcctcgac ggaggtgttc accaggctga tgtcgaactc cgactcggcg gccagctcca
    37741 ccttcgcggc caccagccgg cgctcgatca cctcgggcga ctcggtgccc cggccggtca
    37801 gccggcggac cagctcgtcc cagctcggcg gtgccaggaa gaccagctgt gagtccggca
    37861 tcgagtcctt gacctgccgc gcgccctgga ggtcgatctc caggagtacg ggctcgccgg
    37921 cctccaggcg cctctgcacc gcgagacgcg gtgtgccgta gcggttgccc gcgaactcgg
    37981 cccactccag cagctcgccg ttggcgacca gcttgtcgaa ctcctcgtcg gtgacgaaga
    38041 agtactggac gccgtggcgt tcgccgggac gcggctttct ggtggtggcc gacaccgaga
    38101 gccatacctc ggggtggacc ttgcgcatat gcgcgacgac cgtgctcttg ccgacgcccg
    38161 aagggccgga gagcacggtc agccgcggat gtacctctgg tgccatgcag cgattatcca
    38221 ggttcccggg agtgcccggg aacgtcaggc gggactgccg ccgaactcgc gttcaagcga
    38281 cgcgatctgg ttggagccga gaccccggac acggcggctt tcggagatgc cgagtcgctc
    38341 catgatctgc ttggcgcgca ccttgcccac gccgggcaga gattcgagga gggcggagac
    38401 cttcatcttg ccgatgacgt cgttctcctg accctgcttg atgacctcgt ggagggaggc
    38461 gccggagtgc ttgagtcgat tcttgacctc ggcccgctcc cggcgagccg cggcggcctt
    38521 ttcgagcgcg gctgcgcgct gttcaggggt aaggggcgga agagccacgc ctacgtcacc
    38581 tcggatgtcg aactgtcgga tacggaccgg tgcggaactg gttcgtccca caccaggcga
    38641 gcaacgagcg atggttccgc gcgttgactc tcgacggaga ctagcggtgc agaccgctct
    38701 cgtcagcgag aacagccgaa aagtcctggt cagcatcgct cgaccaggac atttccggca
    38761 aaacaacccg cttttctgtc aggatccgcg ttcgaaccgc gtcagcgcgc tcgccgagcg
    38821 ccctcgaccg ccgtccggac gtcgtcgccg aaccgctccg ccgccgcacg caggacgtaa
    38881 acatccgggc cgtgacggag tactccccgg ctcacactcg gcaccacgtc gccgacggcc
    38941 gcgccgaaca cagcaggaag gtccgcgggg gtcgcgccct gcgccccgat gccgggggcg
    39001 aggagcggcc cgttgatcgc gagattcacc ccggcctcgg cgagggtcgc cccgacgacg
    39061 gcgccgaccg aaccgagcgg cgtcgccccg gcgttctccg cggcggcgtg gtcgagcatc
    39121 gtctgggcga ccgagcaacc gccctgggtg gtggcccgct ggacctcggc gccctccggg
    39181 ttggaggtga gcgccagcac gaagagaccg gagccgctga cgcgcgcggc gtccagcgcg
    39241 gggcgcagcg aaccgaagcc gaggtacggc gagaccgtga gggcgtcgga gaagagcggg
    39301 ctgtccttgt cgaggtacgt ggcggcgtac gcgcccatgg tggagccgat gtcgccgcgc
    39361 ttggcgtcca tcaggaccag cgcgccggcg gcccgcgcct cggcgaccgc cttctccagg
    39421 acggcgacac cgcgcgagcc gaaccgctcg aagaacgccg actgcggctt cagtacggcc
    39481 acgcggtcgg ccagcgcctc gacgacggta cgggtgaagg ccgtcaggcc cgcgacgtcg
    39541 tcgctcaggc cccagtcgtg cagcagcgag gcgtgggggt cgatgcccac gcagagcggg
    39601 ccccgggtgt ccatggcgcg gcgcaggcgt gccccgaagg gctcccgctc cgtgtccgcg
    39661 cccacggacg cggcggtgac ggtggcgtcg ttcacgcgtg cgccttcctg gtgtcggcgc
    39721 cgacggcctc ggcgagggtg gcgtactgac tggtggccag ccgggcggcg agccccttgt
    39781 ggatgccccg gctccagaac gggccctggt agatgaaggc gctgtagccc tggacgagcg
    39841 tcgcgcccgc caggatccgc tgccaggcgt cctcggcgtt ctcgatgcct cccacgccga
    39901 ccagggtgat ccggtcgccc acgcgcgcgt acagccgcct caggacctcc agcgagcgcg
    39961 ccttcagggg cgccccggac agtccgccgg tctcggcgag cagggacggg gccgtcttca
    40021 ggccgaggcc gtgccgcgcg acggtggtgt tggtggcgat gatgccgtcc aggcccagct
    40081 ccacggccag gtcggcgacg gcgtcgatgt cgtcgtcggc gaggtcgggg gcgatcttga
    40141 ccaggagcgg gacacgccgc tgcggtacga cgtggtcggc ggcctcgcgt acggcggtca
    40201 ggagcgggcg cagctggtcg acggcctgga ggttccgcag accgggggtg ttcggggacg
    40261 agacgttgac gacgaggtag tcggcgtggg cggccaggcg ctcggtcgac gtcacgtagt
    40321 cgccgatcgc cgcgtcgtcc ggtacggcct tggtcctgcc gatgttgacg ccgaccgtcg
    40381 tacggaagat ctcgcggcgg gtggccaggc gcagggcgac ggtggccgat ccgtcgttgt
    40441 tgaagcccat gcggttgatc agcgcccggt cggcgggcag ccggaacagc cgctgcgggg
    40501 cgttgcccgg ctgcggctgc ccggtgaccg tgccgatctc gacatggtcg aagccgagca
    40561 tcgacatgcc gtcgacggcg acggcgttct tgtcgaagcc ggcggcgagg ccgaaggggc
    40621 cgtgcatccg cagcccgaag gcctcggtgc gcagcgcctc gtaacgaggg gcgagcgccg
    40681 cggcgacgaa ggtgcgcagc accgggacgc ggacgacgag cccgatccag cggaaggcca
    40741 ggtggtgcgc ctgctcgggg tccatgcgtc ggaagaggag ccggaagagg agtcggtaca
    40801 tggcagcagg ctctcctact cttcgcgcgc ggcgatgagg tgctcggcgt gttcctggag
    40861 cgaacgcacg ccgaccccgc cgtggttgag ggcgtcgatg ccctgtacgg ccgccgcgag
    40921 ggcctggacc gtcgtcaggc acgggacgcc gcgcgccaca gcggcggtac ggatctcgta
    40981 gccgtcgagc cggccgccgg tgccgtacgg cgtgttgacg atgaggtcga cctcgccgtc
    41041 gtggatgagc tggacgatgg tccgctcgcc gttcggtccg gtgccctcga actgcttgcg
    41101 cacgatcgtg gcgttgatgc cgttgcggcg caggacctcg gcggtgccgg aggtggcgag
    41161 cagctcgaag ccgtgcgcga ccagttcacg cgccgggaag atc
//
