LOCUS       NZ_WRXL01000002        20333 bp    DNA     linear   CON 23-OCT-2024
DEFINITION  Haloarcula salina strain YGHS18 scaffold2, whole genome shotgun
            sequence.
ACCESSION   NZ_WRXL01000002
VERSION     NZ_WRXL01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Haloarcula salina
  ORGANISM  Haloarcula salina
            Archaea; Methanobacteriati; Methanobacteriota; Stenosarchaea group;
            Halobacteria; Halobacteriales; Haloarculaceae; Haloarcula.
REFERENCE   1  (bases 1 to 655411)
  AUTHORS   Zhang,W.J. and Cui,H.L.
  TITLE     Halomicroarcula salina sp. nov., isolated from a marine solar
            saltern
  JOURNAL   Int J Syst Evol Microbiol 65 (Pt 5), 1628-1633 (2015)
   PUBMED   25721722
REFERENCE   2  (bases 1 to 655411)
  AUTHORS   Zhang,W.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-DEC-2019) Department of Biology, Anhui Normal
            University, No. 1 Beijing East Road, Wuhu, Anhui 241000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.9.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_010119195.1-RS_2024_10_23
            Annotation Date                   :: 10/23/2024 11:42:32
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,870
            CDSs (total)                      :: 3,820
            Genes (coding)                    :: 3,795
            CDSs (with protein)               :: 3,795
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 44
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 25
            CDSs (without protein)            :: 25
            Pseudo Genes (ambiguous residues) :: 0 of 25
            Pseudo Genes (frameshifted)       :: 11 of 25
            Pseudo Genes (incomplete)         :: 16 of 25
            Pseudo Genes (internal stop)      :: 5 of 25
            Pseudo Genes (multiple problems)  :: 6 of 25
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:19:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 368290
            Orig. end                         :: 388623
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            WRXL01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20333
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20333
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20333
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10333](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10333
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            916..1713
                     /locus_tag="GM656_RS06850"
     CDS             916..1713
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007143855.1"
                     /locus_tag="GM656_RS06850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_162412921.1"
                     /transl_table=11
                     /translation="MIVVATEDFKVYHGVVTELRDRGVSFTTIEPGDEWPERTRVAVVA
                     AGDAVEVPDGVEVVRAESDRPRQAVESAISTLRGGDGRTVIGIDPGERPGIAVLHGEMV
                     VAAFQVPAAEAGEIVRREVEDAVDPVVRIGDGARLVGARIIDDIQSVPVELVDETGTTP
                     YLGSGARGMGDVLAAVNIARLDGEEIESRPIEPTAGELTRIKDRSREASDTNRAIGEGL
                     ARRVAAGELTVEEALAEHGGTGSDDGEETDDGERPTDAESDDA"
     gene            complement(1714..3057)
                     /gene="larC"
                     /locus_tag="GM656_RS06855"
     CDS             complement(1714..3057)
                     /EC_number="4.99.1.12"
                     /codon_start=1
                     /gene="larC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011223679.1"
                     /locus_tag="GM656_RS06855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nickel pincer cofactor biosynthesis protein LarC"
                     /protein_id="WP_162412922.1"
                     /transl_table=11
                     /translation="MRTLAFDGRTGAAGDMLLGALLAAGADRDALSPVEDALDVAYAVS
                     EVDRCGVAATRVEVLLTDDGGDDEQSDRGREHGDSDEGHDHAHSHDGDGGHDHQHDHDG
                     GHDHGDHDHAPAEGHGPSRTYGEVVDLVEEMPLPEEVRDDALAIFEILGTAEASVHGTD
                     LEGTHFHEVGADDAIADVVGACLLLEDLGVERVLTTPLATGGGTVEMSHGTYPVPTPAV
                     VEIAERADWSLRGGPVDAELLTPTAAAILAHVAAGVDSLPPLRVDASGYGAGGWDFDDR
                     PNVLRASVGETAGRLRRDDITVLETNVDDVSPEVLGDLQRSLGDVGARDVSVVPATMKK
                     SRPGHIVKVICKPGDAERVARRLAEVTGTLGVREHGAGHRWVADREFETVALAVGDETF
                     EVTVKVASDGDGSVFDVSAEYDDAAAVAEATGLSVREVSQRAERMVRE"
     gene            complement(3170..3586)
                     /locus_tag="GM656_RS06860"
     CDS             complement(3170..3586)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004957251.1"
                     /locus_tag="GM656_RS06860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="universal stress protein"
                     /protein_id="WP_162412923.1"
                     /transl_table=11
                     /translation="MVFLVPFDGSPLADAALDRAVAYAAALDEDVVAVAFIPTGDDYAE
                     RRRRVDPTEDFAAETAASDLRRKIEEATDDAELRYDDVSAHSTSELSATIRQTARDVDA
                     GVVFLGSDDSENIVVPIEDLTDGDGYDVHIVRQD"
     gene            3842..6067
                     /locus_tag="GM656_RS06865"
     CDS             3842..6067
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015322678.1"
                     /locus_tag="GM656_RS06865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CDC48 family AAA ATPase"
                     /protein_id="WP_162412924.1"
                     /transl_table=11
                     /translation="MNEVQLEVAKAYPNDSGRGIARLDPDTLLHLKLSPGDIIEIEGSD
                     TTAAKVWRADRQDWNTDTVRIDGFTRQNADVGIGERVTIRKAEAEKADKLVLAPPEEAS
                     VQFGSDAAGMVKRQILKRPVVERDIVPVMSSTNHPFMRSPGQAIPLIAVETDPEGVCLI
                     TEDTEVELREEPISGFEKTGGGITYEDIGGLQNEIQRVREMVELPMKHPQIFKKLGIEP
                     PQGVLLHGPPGTGKTLLAKAVANETSASFFSIAGPEIISKYYGESEQQLREIFEDASEE
                     APSIIFIDELDSIAPKREDVTGEVERRVVAQLLTMMDGLESRGQVIVIAATNRVDSVDP
                     ALRRPGRFDREIEIGVPDEVGREEILQIHTRGMPLSDDVNLAKLATDTHGFVGADIESL
                     TKEAAMKALRRYLPEIDLDEEDIPPSLIDRMIIKRDDFKGALNEVSPSAMREVLVELPK
                     VSWDSVGGLTEAKEQVQEAVEWPMNSPEKFERMGVTPPSGVLLYGPPGTGKTLMAKAVA
                     NETDANFISVRGPQLLSKWVGESEKAIRQTFRKARQVAPTVIFFDELDSLAPGRGGEMG
                     SNVSERVVNQLLTELDGLEEMEDVMVIGATNRPDMIDPALIRSGRFDRLVMIGEPDVDG
                     REQILKIHTDDTPLSPDVSLRELAEVSEGFVGSDLESIAREAAIEALREADDAEEVEMR
                     HFRQAIDSVRPTITDDIREYYEQMEEEFKGGSSPQRQAGTGGRIGFQ"
     misc_feature    3857..3859
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    4652..4654
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(6104..7462)
                     /locus_tag="GM656_RS06870"
     CDS             complement(6104..7462)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008311893.1"
                     /locus_tag="GM656_RS06870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_194242949.1"
                     /transl_table=11
                     /translation="MPSHGSRSLPLLLSVLLVGSLLALAAPVGAAPPPRPLCDACGDQF
                     ATTAERHGVSLAVERSTATVAVHENGTATWVVRNHLAGDGARLRSNATLRRAIGDRAMW
                     DVEFLNATVSRSGVVTLRYREPDFAEPAIGGTFRSGAFTETYGYRNIDGLGADRLVVVA
                     PPGTRVGRPLPDSTVSSDGRQMHITSFDRGGIVTFVPQESAVGPLLSLLAVVTMRGPAV
                     LGNLLTNVAVPAAAFGVLVGAVGGGLSTIRHRLATGARGAGCALAGIGLLVALAPLVAG
                     GLSVLSSSVAPLLGVGIAFVALGLGLSRTGPEWVRSFPALVGVAVGGLAVAVLATAVGT
                     LAVGIRGLTLAMWTSARFLVPVFALLPAGYAVGAGRRRLGVATAVLGFVLALAPTATLY
                     SPFYGFGVLVFVFVLGMAAGVVALGAPLFGVGFVLATTRPSDEAENDAARGEQ"
     gene            7669..8682
                     /locus_tag="GM656_RS06875"
     CDS             7669..8682
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016628 - oxidoreductase activity, acting
                     on the CH-CH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (30-331). E-value: 1.2e-19.
                     Score: 62.5. Matches aSDomain:
                     nrpspksdomains_GM656_RS06875_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004591600.1"
                     /locus_tag="GM656_RS06875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_162412925.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 8.5e-22, bitscore:
                     73.0, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQTHRVYRLAKRPEGTPGRDTFDLSEEPVPEPGPGEALVRTLYL
                     SVDPYMRGRMSAAESYAEPWDVGDPLRGAVVGEVVESNGAGFEAGDVVTGDLQWAEYAT
                     APGPALTRVDPDRAPISTALGVLGMPGLTAYFGTREVARPSAGETFVVTGAAGAVGSVA
                     GQIAKLRGARVVGFAGSDEKVAFLEDDLGFDAGINYKATDDYRAALDEAAPNGVDAYFD
                     NVGGEITDAVFTRLNTDARVAVCGQISQYNAEEMPVGPRKLSQVIQTRATVEGFLVSDF
                     EPRFEQAATRLGQWVSAGDIAYRETVTEGLENAPDAFLGLFEGDNIGKQLVKVADR"
     aSDomain        7759..8661
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GM656_RS06875_PKS_ER.1"
                     /evalue="1.20E-19"
                     /label="GM656_RS06875_PKS_ER.1"
                     /locus_tag="GM656_RS06875"
                     /protein_end="331"
                     /protein_start="30"
                     /score="62.5"
                     /tool="antismash"
                     /translation="PEPGPGEALVRTLYLSVDPYMRGRMSAAESYAEPWDVGDPLRGAV
                     VGEVVESNGAGFEAGDVVTGDLQWAEYATAPGPALTRVDPDRAPISTALGVLGMPGLTA
                     YFGTREVARPSAGETFVVTGAAGAVGSVAGQIAKLRGARVVGFAGSDEKVAFLEDDLGF
                     DAGINYKATDDYRAALDEAAPNGVDAYFDNVGGEITDAVFTRLNTDARVAVCGQISQYN
                     AEEMPVGPRKLSQVIQTRATVEGFLVSDFEPRFEQAATRLGQWVSAGDIAYRETVTEGL
                     ENAPDAFLGLFEGDNIGKQL"
     gene            complement(8751..9893)
                     /locus_tag="GM656_RS06880"
     CDS             complement(8751..9893)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005538172.1"
                     /locus_tag="GM656_RS06880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CBS domain-containing protein"
                     /protein_id="WP_162412926.1"
                     /transl_table=11
                     /translation="MDIADIATREFVEVDANKRLGKVRSIFERENPKGIIVTDDGAYAG
                     VITQKQLVQSHVEDNAKAGAMTRSAPKVGRTDDVREVARVLVEGGVKLAPVFEAGELWG
                     IVTEDDILDAVLENLDALTVEDIYTQDVITVSEDTNVGQVVNLLRKHGISRLPVLDETD
                     SLTGMVTRHDIVDVVVRDMNKATRGDRAGEIERVLDLPVYDVMNSPVETVRVGDSVEDA
                     VARMLENDFAGLVVTPEDDDSAVVGILTKTDVLRALTYTEEEHMDVQITNITLLDTISR
                     EDIRADIETVADKYQAMQVQHAHVRFHEHKEKLRGTPLIQCQIRLRTNKGQAAGSGEGY
                     GAETAFNVALDKLERNVLELKGVQADEEYRGQLLRKLGEL"
     gene            10001..10333
                     /locus_tag="GM656_RS06885"
     CDS             10001..10333
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl_fung"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004591602.1"
                     /locus_tag="GM656_RS06885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lycopene cyclase domain-containing protein"
                     /protein_id="WP_162412927.1"
                     /sec_met_domain="Lycopene_cycl_fung (E-value: 4.8e-14,
                     bitscore: 48.0, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLPDIGVFGPYTYLVTEVVWGSVALALLWRAGALREAARTIAVLY
                     PIAYVWDWYTLTVGVFSIDLRTGVDLLGIPVEEHIFIVVVPALVLGIHETLRVRTSDDS
                     TERSGR"
     gene            10503..10994
                     /locus_tag="GM656_RS06890"
     CDS             10503..10994
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008311549.1"
                     /locus_tag="GM656_RS06890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HTH domain-containing protein"
                     /protein_id="WP_162412928.1"
                     /transl_table=11
                     /translation="MTDTIPTPHIELYVRSMLPDGAHERQEEVIDRLDTLEENDQIASF
                     NVIVWGKQIAPQSAAAGTAEGQFILNRVAEFKQWALSNNVSFESFYQRTQVDSEAAESA
                     YDAMTLPVMGLAEYDGDELAHVAPCTKGDTVHTIVDRLERLEAGQPPALEQERRGVSVV
                     "
     gene            complement(10991..11350)
                     /locus_tag="GM656_RS06895"
     CDS             complement(10991..11350)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008311551.1"
                     /locus_tag="GM656_RS06895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_162412929.1"
                     /transl_table=11
                     /translation="MDSLDTADSFEQFVLLSVVELTVAGETPVHSYDVAQTAKAHLDDL
                     EREPFGGVERQEIIAALRTLADAGLLTKARTESATGKGRPAYELAVEPEEVLTMLEGAE
                     SFGPYVETIRAETAD"
     gene            complement(11409..12152)
                     /locus_tag="GM656_RS06900"
     CDS             complement(11409..12152)
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /GO_function="GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA]"
                     /GO_process="GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024880.5"
                     /locus_tag="GM656_RS06900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bifunctional 2-polyprenyl-6-hydroxyphenol
                     methylase/3-demethylubiquinol 3-O-methyltransferase UbiG"
                     /protein_id="WP_162412930.1"
                     /transl_table=11
                     /translation="MTSTVFKQLYRSALADSERLDEDSVLLDIGAKDGKIASALADAIG
                     CRAIVLDIDFDEDATDRDCDLIRGDGTEIPLPDDSVDAIVSNMVFEHVPDEEALIADTA
                     RVLSDDGVFISICPNRAWPGDGHGYPLGMPWLPESIGGRVARPYDQKYERGEGWYREAY
                     HPVWSITVRRELSRYFETVEYRSGDLLDLDLDASNGKQRLLETFAEPLELAFSSRLGRR
                     LVEAVFPTPVYVSKHPKRGRRRPNG"
     misc_feature    complement(11544..11546)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(11745..11747)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     tRNA            complement(12626..12700)
                     /anticodon=(pos:complement(380953..380955),aa:Val,seq:gac)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="GM656_RS06905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /product="tRNA-Val"
     gene            complement(12626..12700)
                     /locus_tag="GM656_RS06905"
     gene            12879..13874
                     /gene="trpD"
                     /locus_tag="GM656_RS06910"
     CDS             12879..13874
                     /EC_number="2.4.2.18"
                     /GO_function="GO:0004048 - anthranilate
                     phosphoribosyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="trpD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004518136.1"
                     /locus_tag="GM656_RS06910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="WP_162412931.1"
                     /transl_table=11
                     /translation="MKEYIERVTDGEDLTQEEARRVATTVFDDATDAQIGALLTALRAK
                     GETEAEIAGFAEGMRDAARTIRPDREGMVDTCGTGGDDYNTINVSTTSAIVAAGAGVPI
                     AKHGNYSVSSASGSADVLEEVGVDIEAEPEDVEETIEREGIGFMLAPVFHPAMKAVIGP
                     RKELGIRTVFNILGPLTNPADADAQVLGVYDPDLVPVMAEALARLEVERALVVHGSGLD
                     EIAIHGETAIAEVTGDRIAEYTITPEDIGLETHDIEDIAGGEPAENAADLRGIVSGELT
                     GAKRDIILANAGAAIYVAGVADTHEEGVELARDAIESGDAAAKLDDLVGA"
     gene            13871..14515
                     /locus_tag="GM656_RS06915"
     CDS             13871..14515
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011223673.1"
                     /locus_tag="GM656_RS06915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="WP_162412932.1"
                     /transl_table=11
                     /translation="MTRVKICGVTDDEDRDAVVAAGADAVGVIHGVPVDTPREVDEATA
                     ADLVDGVPPLVTSVLVTMPTTVQEAVTRVDAVEPDAVQVHDGLSPAELGALDSRITQSI
                     VAVVSADAPDIADYAAHADALLVDSVDADGGGGTGETHDWERTRDLVDSLDVPVVLAGG
                     LTPENVAAAVETVDPFAVDVASGVESEGGRKDHDAVERFVRNATRATEGSA"
     gene            14512..16158
                     /gene="trpE"
                     /locus_tag="GM656_RS06920"
     CDS             14512..16158
                     /EC_number="4.1.3.27"
                     /GO_function="GO:0004049 - anthranilate synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="trpE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1018: isochorismate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006109034.1"
                     /locus_tag="GM656_RS06920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="anthranilate synthase component I"
                     /protein_id="WP_162412933.1"
                     /transl_table=11
                     /translation="MSLDLSREAFVEQAEADRPVVVRTAAELDADVEPLAAYAALSGRT
                     GDAAESDYTFLLESAEKVASSDPDGAFAPETDDRHARFSFVGYDPRAVVTVTGDDSEVQ
                     VLDERYADLVTTDGGDVVDDLRAAMPDVTLRNFPEMDRQHLEGGLVGFLSYDAVYDLWL
                     DEVGLDRPDSRFPDAQFVLTTSTVRFDHVEETVSLVFTPVVRQDEDAGERYDELVAEAE
                     RVDAVLSDLGPLSTGGFRREREVAGPQDEYEAAVERAKEYVLSGDIYQGVISRTRELYG
                     EVDPLGFYEALRAVNPSPYMYLLGYDDLTIVGASPETLVSVAGDHVVSNPIAGTCPRGN
                     SPVEDRRLAGEMLADGKERAEHTMLVDLARNDVRRVAEAGSVRVQEFMNVLKYSHVQHI
                     ESTVTGRLSPEKDAFDAARATFPAGTLSGAPKIRAMEIIDELERSPRGPYGGGVGYFDW
                     GGDADFAIVIRSATIEDTDESDRITVQAGAGIVADSDPESEYVETEQKMDGVLTALERI
                     EDDRSTDGFDRTDGDEADTTDGDEHAGEVPR"
     gene            16155..16778
                     /gene="trpG"
                     /locus_tag="GM656_RS06925"
     CDS             16155..16778
                     /EC_number="4.1.3.27"
                     /GO_function="GO:0004049 - anthranilate synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="trpG"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1249: carbamoyl phosphate synthase small subunit"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014040834.1"
                     /locus_tag="GM656_RS06925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="anthranilate synthase component II"
                     /protein_id="WP_162412934.1"
                     /transl_table=11
                     /translation="MSASRPAGEDAVRDDLRVLFVDNFDSFTYNLVEYVSEHAETEVVR
                     NTASLDDVRAFDPDAIVLSPGPGHPKNERDVGVTLDVLREISPDVPTLGVCLGLESAVY
                     AYGGTIGRAPEPIHGKAFPIDHDGEGVFRGLEQGFQGGRYHSLVAEGVPDEFVVSATTE
                     TADGTELVMGVRHREHPIEAVQFHPESVLTSVGHDVIRNFLAGL"
     gene            complement(16775..16963)
                     /locus_tag="GM656_RS06930"
     CDS             complement(16775..16963)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008311561.1"
                     /locus_tag="GM656_RS06930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_162412935.1"
                     /transl_table=11
                     /translation="MLWLLQLGGVPSLPALLGGLLVIALVLLVGRFVMKMAWRIVVLAI
                     VAVAVLWLLGMLGFQII"
ORIGIN
        1 ccccccactc gcgggtgagc acgagcgcct cggaatcgag gtcgtacccc gagaggtcgt
       61 cccaggcgta gaagcgccgc gcgccggggt ggcggacttc gaggcccgcg tcggtggcga
      121 ccgccgtccg ggtcccgccc gtggtgatga ggacgaaccc cgacgggaac agcacctgcc
      181 cggtgtactg caacagcgag gactccagaa tcgtgccgac ggcgaagccg acagtggcga
      241 cgccggcgaa cgccccgccg tgacgcaacc gtcgccgctg ctcgcgctcg ggccagctcg
      301 cggtccagcg ggcgagttcc gggcgtccgg tggtggccga gacggcgtat ctcgtgtggg
      361 acatgactgc gatggcgatg ccgaacacgg acgcgaagag cccacaggcc accgccacga
      421 gtccgacggg gccgaccgcg ccagtctgtg cgaagccggc gacggcgtag ccgacggcga
      481 gcgcgatgaa cgcccatcgc ttgcgggtcg caccgagggc caccgccagc gacggccggg
      541 atcggagcca ccacgcagtg gcgaggccga cggtgacgag cgcggcgacg agcgtcacgg
      601 ccagcaccac tggactgcgc gagaccgtcc acgcgacgag cagcaccacc ggcggcgtcg
      661 ccaacaggcc gagatacccc ccacagatcg ccccgaatcg cgggtcctcg tcccggcacg
      721 cgccggcggc ggcttgtgcc gaatgcatca ccgttcgttc tcacacttgt tactaaaaag
      781 tccattattt ccaagaggta tctatagcag tgtgataata gccctattcg acggtatctg
      841 gtaactatcg ggagctcccg cgacggcgtc aacgcgggcc cacacctgta agtacgcagc
      901 ccgcgaaatc gaggcgtgat cgtcgtcgcc accgaggact tcaaggtcta ccacggcgtg
      961 gtcaccgaac tccgtgaccg cggggtgtcg tttaccacta tcgaaccggg ggacgagtgg
     1021 cccgagagaa cgcgggtggc ggtcgtcgcg gccggcgacg cggtcgaggt gcccgacggc
     1081 gtcgaagtcg tgcgggcgga gtcggaccgc ccccggcaag ccgtcgagtc ggccatttcg
     1141 acgctccggg gcggcgacgg gcggaccgtc atcggtatcg accccggaga gcgcccgggc
     1201 atcgcggtct tgcacgggga gatggtcgtc gccgcgttcc aggtgccggc ggctgaagcc
     1261 ggtgagatcg tccgccgaga ggtcgaggac gcggtcgatc cggtcgtccg catcggcgac
     1321 ggtgcgcgac tcgtcggcgc gcgcatcatc gacgacatcc agtcagtccc ggtggaactg
     1381 gtcgacgaga ccgggacgac gccctatctg gggtccgggg cacgcgggat gggcgacgta
     1441 ctggccgcgg tcaacatcgc ccgcctcgac ggcgaggaga tcgagagccg gcccatcgag
     1501 ccgacggcgg gcgaactgac gcggatcaag gaccgctcgc gggaagcgag cgacacgaac
     1561 cgcgctatcg gggaggggct cgcaaggcgc gtcgcggctg gggaactgac cgtcgaggaa
     1621 gcgctcgcgg aacacggggg tacggggagt gacgacggcg aggagaccga tgacggcgaa
     1681 cgaccgacgg acgccgagag cgacgacgcc tgactactct ctgaccatcc gctctgctcg
     1741 ctggctgact tccctgacag agaggcccgt cgcctcggcg acggccgccg cgtcgtcgta
     1801 ctcggcgctc acgtcgaaca ccgacccgtc gccgtcgctc gcgaccttga ccgtcacttc
     1861 gaaggtctcg tcgccgacgg cgagcgcgac ggtctcgaac tcgcggtcgg cgacccagcg
     1921 gtggcccgcg ccgtgttccc tgaccccgag cgttcccgtc acctcggcga ggcggcgggc
     1981 gacgcgttcg gcgtccccgg gcttgcagat gactttcacg atgtggccgg ggcgcgactt
     2041 cttcatcgtc gccgggacga ccgacacgtc gcgcgcgccg acatcgccga gcgagcgctg
     2101 gaggtcgccg agcacctcgg gagacacgtc gtcgacgttc gtctccagca cggtgatgtc
     2161 gtcgcggcgc aggcggcccg cggtctcgcc gaccgacgcc cggaggacgt tcggccggtc
     2221 gtcgaagtcc cagccgccgg ctccgtagcc ggacgcgtcg acccgcagcg gcgggaggga
     2281 gtcgacgccc gctgcgacgt gcgcgaggat ggccgcggcg gtgggtgtga gcagttccgc
     2341 gtcgacggga ccgccccgga gcgaccagtc ggcccgctcg gcgatctcga cgacggccgg
     2401 cgtcgggacg gggtaggtcc cgtggctcat ctcgacggtc ccgccgccgg tggcgagcgg
     2461 cgtcgtcagc acccgttcga cgccgaggtc ctcgagcaac aggcaggccc cgaccacgtc
     2521 ggcgatggcg tcgtcggccc cgacctcgtg gaagtgcgtc ccctccaggt ccgtcccgtg
     2581 gaccgacgcc tcggcggtcc ccagaatctc gaagatagcg agcgcgtcgt ctctgacttc
     2641 ctcggggagg ggcatctcct cgacgaggtc cacgacttcg ccgtacgtcc gactgggtcc
     2701 gtggccctcc gcgggcgcgt ggtcgtggtc gccgtggtcg tgacccccgt cgtggtcgtg
     2761 ctggtggtcg tggccgccat cgccgtcgtg cgagtgggcg tggtcgtgac cctcgtccga
     2821 gtctccgtgt tcgcggccgc ggtcgctctg ctcgtcgtca ccgccgtcgt cggtgagaag
     2881 cacctcgacg cgcgtggcgg cgacgccgca gcggtcgacc tcggagacgg cgtacgccac
     2941 gtcgagcgcg tcttcgaccg gcgacagggc gtcgcggtcc gcaccggccg cgagcagcgc
     3001 gccgagcagc atgtcgcccg ccgcgcccgt ccggccgtcg aaagcgagtg ttcgcatagt
     3061 cggggcctcg cgccccgcga gtaaaagccc ggtcatacgg acgctcgtcg tcgtgtaccg
     3121 gtgttcggcg aggcggggtg aacaccgaga cctcgttacg acggccgtct cagtcctggc
     3181 ggacgatgtg gacgtcgtag ccgtcgccgt cggtgaggtc ctcgatgggg acgacgatgt
     3241 tctcgctgtc gtcgctcccg aggaagacga cgcccgcgtc gacgtcgcga gcggtctgtc
     3301 ggatggtcgc cgacagctcg ctcgtggagt gggcgctcac gtcgtcgtag cggagttcgg
     3361 cgtcgtcggt cgcctcctcg atcttgcgtc ggaggtcgct cgccgcggtc tcggcggcga
     3421 agtcttcagt ggggtccacg cggcggcggc gttcggcgta gtcgtcgccg gtcgggatga
     3481 aagcgacagc gacgacgtcc tcgtcgagcg cggcggcgta ggcgactgcg cggtcgagcg
     3541 cggcgtctgc gagcggcgat ccgtcgaagg ggacgagaaa gaccatatca gcgctatcgg
     3601 gtccagcctt atgaaacgag gcgattccgg cggtcggcgc agtgtggtga cagacaccct
     3661 gacctgtcgg gtccggagaa ccccgcggtc gcgctcggtc ccgtcgcggc ctcgctgttc
     3721 gctgtcgctc tcgaccccat gttattaggt aacatataaa tccgtcgccg ggcgtcttgc
     3781 ccgccggtag cataaagcat atctccgggg ctaccccagt tcgttataag ctgactctac
     3841 tatgaacgaa gtccaattag aagtggcgaa ggcgtacccc aacgactcgg gtcgcggcat
     3901 cgcccgactc gaccccgata cgctgcttca cctcaagctc tcgcccggcg acatcatcga
     3961 gatcgagggc agcgacacga cggcggcgaa ggtctggcgc gccgaccgcc aggactggaa
     4021 cacggacacc gtccgcatcg acgggttcac gcgccagaac gccgacgtgg ggatcggcga
     4081 gcgcgtcact atccgcaagg ccgaggccga gaaggcggac aagctcgtcc tcgcgccccc
     4141 tgaggaggcg tcggtccagt tcggctccga cgccgccggc atggtcaaac ggcagatcct
     4201 caagcgcccc gtcgtcgagc gcgacatcgt ccccgtgatg tcctcgacga accacccgtt
     4261 catgcgctcg cccggccagg ccatcccgct catcgccgtc gagacggacc ccgagggcgt
     4321 ctgtctcatc accgaggaca cggaggtcga actccgcgag gaacccatct ccggcttcga
     4381 gaagaccggc ggtggcatca cgtacgagga catcggcggc ctccagaacg agattcagcg
     4441 cgtccgcgag atggtcgaac tgccgatgaa acacccccag atcttcaaga agctcggcat
     4501 cgagccgcca cagggggtcc tgctccacgg tccgccgggg acggggaaga ccctgctcgc
     4561 gaaggccgtc gccaacgaga cctccgccag tttcttctct atcgccgggc cggagatcat
     4621 ctcgaagtac tacggggagt ccgaacagca gttacgcgag atattcgagg acgccagcga
     4681 ggaggccccg tcgatcatct tcatcgacga actggactcc atcgcgccaa agcgcgagga
     4741 cgtgaccggc gaggtcgagc gccgcgtcgt cgcccagctg ctgacgatga tggacggcct
     4801 cgaatcgcgg ggccaggtca tcgtcatcgc cgccaccaac cgcgtcgaca gcgtcgaccc
     4861 ggcgctgcgt cgccccggcc gcttcgaccg cgagatcgag atcggcgtcc cggacgaggt
     4921 gggccgtgag gagatcctac agatccacac ccgcgggatg cccctctcgg acgacgtgaa
     4981 cctcgcgaag ctggcgaccg acacccacgg cttcgtcggc gctgacatcg agagcctcac
     5041 gaaggaggcc gcgatgaagg cgctgcgccg ctacctcccc gagatcgatc tcgacgagga
     5101 ggacatcccg ccgagcctca tcgaccggat gataatcaag cgcgacgact tcaagggcgc
     5161 gctcaacgag gtgagtccgt cggcgatgcg ggaggtgctg gtcgagctcc cgaaggtgtc
     5221 ctgggacagc gtcggcggcc tgaccgaggc caaagagcag gtccaggagg ccgtcgagtg
     5281 gccgatgaac agccccgaga agttcgagcg aatgggggtg acgccgccct cgggcgtact
     5341 gctgtacggc ccgcccggca cggggaagac gctgatggcg aaggccgtcg ccaacgagac
     5401 ggacgcgaac ttcatctcgg tgcgtggccc gcagctgctc agcaagtggg tcggcgagag
     5461 cgagaaggcc atccgccaga ccttccggaa ggcccgacag gtcgctccga ccgtcatctt
     5521 cttcgacgag ctcgactcgc tcgcgccggg ccgcggcggc gagatggggt cgaacgtctc
     5581 cgagcgcgtc gtcaaccaac tgttgaccga actggacggg ctcgaagaga tggaggacgt
     5641 gatggtcatc ggcgcgacga accggccgga catgatcgac ccggcgctca tccgctcggg
     5701 gcgcttcgac cgcctcgtca tgatcggcga gccggacgtt gacggccgcg agcagatcct
     5761 gaagatccac accgacgaca cgccgctgtc gcccgacgtg agcctgcgcg aactggccga
     5821 ggtcagcgag ggcttcgtcg gctccgacct ggagtccatc gcccgcgagg ccgccatcga
     5881 ggcgctccgc gaggccgacg acgccgagga ggtcgagatg cgccacttcc gacaggccat
     5941 cgacagcgtc cgcccgacca tcaccgacga catccgcgag tactacgagc agatggaaga
     6001 ggagttcaag ggcggctcca gcccgcagcg ccaggccggc accggcggcc gcatcggctt
     6061 ccagtaacgt cgcagtcccg ttttctgcgg ttccgctcgc cgctcactgc tcgccgcgag
     6121 cggcgtcgtt ctccgcttcg tcggacggcc gcgtcgtcgc gaggacgaag cccacgccga
     6181 acagcggcgc gcccagcgcg acgacgcccg cggccatccc cagcacgaag acgaagacga
     6241 gcacgccgaa cccgtagaac ggcgagtaca gcgtcgccgt cggcgcgagg gccagcacga
     6301 acccgaggac ggcggtcgcg acgccgagtc gtcgtcggcc cgcgccgacc gcgtagccgg
     6361 cggggagcag cgcgaacacc ggcacgagga acctggcgct cgtccacatc gcgagcgtga
     6421 gcccgcggat tccgacggcg agggtcccga cggcggtggc gaggaccgcg acagcgagtc
     6481 caccgaccgc gacgccgacg agcgccggga acgagcggac ccactcgggt ccggtccgcg
     6541 acaggccgag tccgagcgcg acgaaggcga ttccgacacc aagtagcggg gcgaccgaac
     6601 tgctgaggac cgagagaccg ccggcgacca gcggggcgag cgccacgagg agcccgatgc
     6661 ccgcgagtgc gcagcccgct cccctcgcgc cggtggccag gcggtggcgt atggttgaca
     6721 gtccgccgcc gaccgcaccg accagtacgc cgaacgcggc ggccggcacg gccacgttcg
     6781 tcaagagatt cccgagaacg gcggggccgc gcatcgtcac taccgcgagc aggctcagga
     6841 gcgggccgac ggcgctctct tgcgggacga acgtgacgat gccgccgcgg tcgaacgacg
     6901 tgatgtgcat ctggcgaccg tcagacgaga cggtgctgtc cggcagcggc cgcccgacgc
     6961 gcgtgcccgg cggcgcgacg acgacgaggc ggtccgcgcc gagaccgtcg atgtttcgat
     7021 agccgtaggt ctcggtgaac gccccggagc ggaatgtccc gccgatcgcg ggctcggcga
     7081 aatcgggctc gcgataccgg agcgtgacga cgccgctccg ggagaccgtg gcgttcagga
     7141 actcgacgtc ccacatcgcg cggtcgccga tggcgcgccg gagcgtcgcg ttcgaccgca
     7201 gtctcgcgcc gtcgccggcg agatggttcc ggaccaccca cgtggcggtg ccgttctcgt
     7261 ggacggccac cgtcgccgtg ctgcgctcga cggcgagcga gacgccgtgg cgttccgcgg
     7321 tcgtcgcgaa ctggtcgccg caggcgtcac agagcggtcg tggcggcggc gctgcgccga
     7381 cgggcgcggc gagcgcgagc agtgaaccga cgagcaggac gctcaggagg agggggagcg
     7441 agcgggaacc gtgggagggc atacgtgaca cctttccggg agctgtcaaa tagctggtga
     7501 aggctcaaac cggaactgta ctctcgacgc ggcgggcacc ccttggctcc tgctcatatg
     7561 caccattcga cagatcggga cccctgtcga aaatgtaaaa taaactttga accagtggtt
     7621 ctttctcctt tcgaagcccc ctttcggtag accgggctaa cgaaaccgat gtcgcagaca
     7681 catcgcgtgt accgactggc gaaacgccct gaaggaaccc ccggccgcga cacgttcgac
     7741 ctgtcggagg aaccggtccc agaacccggg cccggcgaag cactcgtgcg gacgctgtac
     7801 ctctcggtcg acccgtacat gcgcggccgg atgagcgccg ccgagtcgta cgcggaaccg
     7861 tgggacgtcg gtgaccccct ccgcggggcc gtcgtcggcg aggtcgttga gtcgaacggc
     7921 gccgggttcg aggccggcga cgtcgtgacc ggcgacctcc agtgggcgga gtacgccaca
     7981 gcacccggcc cggcgctcac gcgcgtcgat cccgatcgcg caccgatctc gaccgccctc
     8041 ggcgtgctcg gcatgccggg tctgaccgcg tacttcggga cgcgtgaggt ggcccggccg
     8101 tcggccggcg agacgttcgt cgtcaccggt gccgcggggg ccgtcggctc ggtcgccggc
     8161 cagatcgcga agctccgggg cgcgcgcgtc gtcggcttcg cgggctccga cgagaaggtg
     8221 gccttcctcg aagacgacct gggcttcgac gcgggcatca actacaaggc gaccgacgac
     8281 taccgcgcgg cgctcgacga ggccgcgccg aacggcgtcg acgcgtactt cgacaacgtc
     8341 ggcggcgaga tcaccgacgc ggtgttcacc cggctcaaca ccgacgcgcg cgttgccgtc
     8401 tgcggacaga tctcacagta caacgccgag gagatgcccg tcggaccgcg gaagctgtcg
     8461 caggtgatcc agacccgggc gaccgtcgag gggttcctgg tgtccgactt cgaaccccgg
     8521 ttcgagcagg ccgcgactcg gctcgggcag tgggtctccg cgggcgacat cgcgtatcgc
     8581 gagaccgtca ccgaggggct cgagaacgcg ccggacgcgt tcctcggact gttcgagggc
     8641 gacaacatcg ggaaacagct cgtcaaagtg gcggaccggt agcccggcga gcggaccctc
     8701 ctgtcggccg ggaaaagcga gagagcgagc gcgaaaacgg gggtatcgcc ttacagttcg
     8761 ccgagcttgc ggaggagctg accgcggtac tcctcgtcgg cctggacgcc cttcagttcg
     8821 aggacgttcc gttcgagctt gtcgagcgcg acgttgaagg cggtctcggc cccgtatccc
     8881 tcaccggagc cggcggcctg ccccttgttg gttcggaggc ggatctgaca ctggatgagc
     8941 ggcgtgccgc ggagtttctc cttgtgctcg tggaaccgga cgtgggcgtg ctggacctgc
     9001 atcgcctggt acttgtcggc caccgtctcg atgtcggctc ggatgtcctc ccgggagatg
     9061 gtgtcgagga gggtgatgtt ggtgatctgc acgtccatgt gttcctcctc cgtgtaggtc
     9121 agcgcccgga gcacgtcggt cttcgtgagg atgccgacga ccgcgctgtc gtcgtcttcc
     9181 ggcgtgacga cgaggccggc gaagtcgttt tcgagcattc gagccacggc gtcctcgacg
     9241 gaatcgccca ctcgaaccgt ctcgacgggg ctgttcatca cgtcgtacac cgggaggtcg
     9301 aggacccgct cgatctcgcc cgcgcggtcg ccgcgggtcg ccttattcat gtcgcggacg
     9361 accacgtcga cgatgtcgtg gcgggtaacc atgccggtca ggctgtcggt ctcgtcgagc
     9421 acggggagcc gggagatgcc gtgcttccgg aggagattga cgacttgccc gacgttggtg
     9481 tcctccgaga ccgtgatgac gtcctgcgtg tagatgtcct cgacggtgag tgcgtcgagg
     9541 ttctcgagga cggcgtcgag gatatcgtcc tcggtgacga ttccccagag ctcgccggcc
     9601 tcgaagacgg gggcgagttt caccccgccc tcgacgagga cgcgcgcgac ctcgcgcacg
     9661 tcgtcggtgc gcccgacctt cggggccgag cgcgtcatcg cccccgcttt cgcgttgtcc
     9721 tcgacgtggg actggaccaa ctgtttctgc gtgataacgc cagcgtacgc accgtcgtcc
     9781 gtgacgatga tgcccttggg gttctcgcgc tcgaagatag atcgaacctt ccccaggcgc
     9841 ttgttggcgt caacctcgac aaactctctg gtggcgatat cagcaatatc catcgtgctt
     9901 cacagttcga ggttctacgt gaagggttat caaccttggt ttagttcctg ggaatcggga
     9961 gacgggccaa gctttaggcc gctggaacca acctttagct gtgctccctg acatcggcgt
    10021 cttcggtccg tacacctacc tcgtcaccga ggtcgtctgg gggagcgtcg ccctcgcgct
    10081 gctgtggcgg gcgggcgcgc tccgcgaggc ggcccggacc atcgcagttc tctacccgat
    10141 cgcgtacgtc tgggactggt acactctcac cgtcggcgtc ttctcgatcg acctccggac
    10201 cggcgtcgac ctgctcggca tccccgtcga ggaacacatc ttcatcgtcg tcgtccccgc
    10261 actcgtcctc ggtatccacg aaacgctccg ggtccgaacg agtgacgata gcacggaacg
    10321 gtcaggacgc taacccgttt tacagcccta actcacgcgg caattcgtcc agcaactgga
    10381 aacgctacca ttgagtgaat gtcacgattt cccacaatag ggctaccgag cgcccaatcc
    10441 ggcgtatgcc gtcacctccc acagtagcta tatgtgtcag ccgagagttg catcgaccag
    10501 ccatgactga cactatcccg acacctcaca tcgagctcta cgtccggtcg atgctccccg
    10561 acggtgccca cgaacgccag gaggaggtca tcgaccgcct cgatacgctc gaagagaacg
    10621 accagatcgc gagcttcaac gtcatcgtct ggggcaagca gatcgctccg cagtcggccg
    10681 ccgccggaac ggcggaaggg cagttcatct tgaaccgcgt cgccgagttc aagcagtggg
    10741 cgctctcgaa caacgtctcg ttcgagtcgt tctatcagcg cacgcaggtg gattccgagg
    10801 ccgccgagtc ggcctacgac gcgatgacgc tccccgtcat gggtctcgcc gagtacgacg
    10861 gtgacgagct cgcccacgtc gcgccctgca ccaagggcga cacggtccac accatcgtcg
    10921 accgtctcga acgcctcgaa gcggggcagc cgcccgcgct cgaacaggag cgacgcggcg
    10981 tcagcgtggt ctagtccgcg gtctccgctc gaatcgtctc gacgtaggga ccgaacgact
    11041 ccgccccctc gagcatcgtc agtacctcct ccggttcgac cgccagttcg taggccggtc
    11101 gccccttccc cgtcgccgac tccgtccgcg ctttcgtcaa caggccagcg tcggcgagcg
    11161 tccggagcgc cgcgatgatt tcctgccgct cgacgccacc gaatggctct cgctcgaggt
    11221 cgtcgaggtg tgccttcgcc gtctgggcca cgtcgtagga gtgtaccggc gtctctcccg
    11281 cgacggtcag ttcgacgacc gagagcagga cgaactgttc gaacgagtcg gccgtgtcga
    11341 ggctgtccat acctgtcact gtcagggttt catcaagaaa gttctggaag gtgaaacgag
    11401 ccagcgactc acccgttcgg acgccgcctg ccgcgcttcg gatgcttcga gacgtacacc
    11461 ggcgtcggaa acaccgcctc gacgagtcgc cgcccgagcc gcgaggaaaa cgccagttcg
    11521 agcggctctg cgaacgtctc cagtaaccgc tgtttcccgt tcgacgcgtc gagatcgagg
    11581 tcaagcaggt ctccggatcg gtactccacg gtctcgaagt acctgctcag ttccctgcgg
    11641 acggtgatcg accacaccgg gtggtacgcc tccctgtacc agccctcgcc gcgctcgtac
    11701 ttctggtcgt acggccgggc cacacggccg ccgatcgact ccggtaacca cggcatcccc
    11761 agcggatacc cgtgcccgtc gcccggccaa gcgcggttcg gacagatcga gatgaacacg
    11821 ccgtcgtcag agaggacgcg cgcggtgtcg gcgatgagcg cctcctcgtc ggggacgtgc
    11881 tcgaacacca tgttcgagac gatggcgtcg acgctgtcgt ccggaagcgg aatctccgtc
    11941 ccgtcgcctc tgataagatc gcagtcgcga tccgtcgcgt cctcgtcgaa gtcgatgtcg
    12001 agtacgatcg cccgacagcc gatcgcgtcc gccagcgccg acgctatctt gccgtctttc
    12061 gcgccgatgt cgaggagcac tgaatcctcg tccagtcgct ccgaatcggc gagcgccgac
    12121 cgatacagct gtttgaagac tgtcgatgtc atgtcgtggg gtagcgagag ccgccgactg
    12181 cggtctgctt gatgcgctac tcaatcggga gcccctatca ctatccgtca cttatccaca
    12241 taagtgggta ataaggttcg tgggacagat gggcgatatg gagcccgtaa ccgcgaaacc
    12301 acacattaag ccgaccaaac ttcgatatct ctagatgtgt cgcagacacc ttcaaaagcc
    12361 cgtccgtcct gcgtatctgt tccattaccg actcgcgtcc acgctgtcgt gactcgaacg
    12421 cacaccgttc gctcgcgaag agtcgataga acgagtccga acagatcgtg acacgaaccg
    12481 agactcgcga cgttctccgg tgacatccac aaaatgggtc ggacggattg tgaaccgaat
    12541 gaagatccgc gtcgctcgcc ttacagggtt caaatcgccc tcacgcacga tttcgtcgct
    12601 cgcgggatgc tcgcgacaga atgagtgggt tcgggcggat ttgaaccgcc ggcctcctcc
    12661 atgtcaagga ggtgtcataa ccgacctaga ccacgaaccc tcactgcgag gtacacctca
    12721 ttgtatcccg ggggtataat tgaaggtttc gaattcggta tcgccacggc gtctgttgat
    12781 tggccccaca cccgcctcgg agacgtaccg gcccgatagg cttaagtcga tgtacggatt
    12841 tgtacatcac aacacgaaaa agtccattgg tgaatacaat gaaggagtat atcgaacgcg
    12901 tcaccgacgg agaggacctg acacaggaag aagcgcgccg cgtcgcgacg accgtcttcg
    12961 acgacgcgac cgacgctcag atcggtgcgt tgctgacggc gctgcgggcg aaaggagaga
    13021 ccgaagccga gatcgccggc ttcgcggagg ggatgcgcga cgctgcgcgg accatccgac
    13081 ccgaccgcga ggggatggtc gacacctgcg ggacgggcgg cgatgactac aacacgatca
    13141 acgtctcgac gacgagcgcg atcgtcgcgg cgggggcggg cgttccgatc gccaagcacg
    13201 gcaactactc cgtgtcgtcg gcctcgggga gcgccgacgt gctcgaagag gtcggcgtcg
    13261 acatcgaggc cgaacccgaa gacgtcgagg agaccatcga gcgcgagggc atcggcttca
    13321 tgctcgcgcc cgtgttccac ccggcgatga aggccgtcat cggtccgcgc aaggaactcg
    13381 gaatccggac cgtcttcaac atcctcgggc cgctgaccaa ccccgccgac gcggacgcgc
    13441 aggtcctcgg cgtctacgac cccgacctcg tcccggtcat ggccgaggcg ctggcccgtc
    13501 tggaggtgga acgcgcgctc gtcgtccacg gcagcggcct cgacgagatc gccatccacg
    13561 gcgagacggc catcgccgag gtcaccggcg accggatcgc ggagtacacc atcacgcccg
    13621 aggacatcgg cctggagacc cacgacatcg aggacatcgc gggcggcgag cccgcggaga
    13681 acgcggccga cctccgcggt atcgtctccg gcgagctcac cggggcgaag cgggacatca
    13741 tcctcgccaa cgccggcgcg gccatctacg tcgccggcgt cgccgacacc cacgaggagg
    13801 gcgtcgagct ggcgcgagac gcgatcgagt ccggcgacgc cgcggcgaag ctcgacgacc
    13861 tggtcggggc atgacgcgcg tgaagatctg tggcgtcacc gacgacgagg accgcgacgc
    13921 cgtcgtcgcg gccggagccg acgccgtcgg cgtcatccac ggcgtcccag tagacacgcc
    13981 ccgcgaagtc gacgaagcga cggcggcaga cctggtcgac ggcgtcccgc cgctcgtgac
    14041 cagcgtcctc gtgacgatgc cgacgacggt ccaggaggcc gtcacgcgcg tcgacgcggt
    14101 cgaaccggac gcggtgcagg tccacgacgg gctctcgccg gcggaactgg gcgcgctcga
    14161 cagccggatc acccagtcca tcgtcgccgt cgtctcggcg gacgcgcccg acatcgcgga
    14221 ctacgcggcc cacgccgacg ctctgctggt cgactccgtc gacgccgacg gcggcggcgg
    14281 cacgggcgag actcacgact gggagcgcac gcgcgacctc gtcgactcgc tcgacgttcc
    14341 ggtcgtcctc gccggcggac tgacgcccga gaacgtcgcg gccgccgtcg aaacggtcga
    14401 cccgttcgcc gtcgacgtgg ccagcggcgt cgagtccgag ggcggccgga aggatcacga
    14461 cgccgtcgag cggttcgtcc gcaacgcgac ccgggcgacg gaggggtcgg catgagtctc
    14521 gacctctccc gcgaggcgtt cgtcgagcag gccgaagcgg accggccagt cgtcgttcgg
    14581 acagccgccg aactcgacgc ggacgtggag ccgctcgccg cctacgcggc gctgagcggg
    14641 cgcaccggcg acgcggccga gagcgactac acgttcctac tggagagcgc cgagaaggtc
    14701 gcctccagcg acccggacgg cgcgttcgcc ccggagaccg acgaccgcca cgcccgcttc
    14761 tcgttcgtcg gctacgaccc gcgggcggtc gtcaccgtca ccggcgacga cagcgaggta
    14821 caggtcctcg acgagcgcta cgccgacctc gtgacgacgg acggcggcga cgtggtcgac
    14881 gacctccgcg ccgcgatgcc ggacgtgacc ctccggaact tcccggagat ggaccgccag
    14941 cacctcgaag gcggcctcgt cggcttcctc tcgtacgacg ccgtctacga cctctggctc
    15001 gacgaggttg gcctcgaccg cccggactcg cggttcccgg acgcccagtt cgtcctgacc
    15061 acgtcgacgg tccggttcga ccacgtcgag gagaccgtct cgctggtgtt cacgcccgtc
    15121 gtcagacagg acgaagacgc cggcgaacgc tacgacgaac tggtcgccga ggccgaacgc
    15181 gtcgacgccg tgctctcgga cctcggcccg ctctcgaccg gcggcttccg ccgcgaacgc
    15241 gaagtagccg gcccgcagga cgagtacgag gccgccgtcg agcgcgccaa ggagtacgtc
    15301 ctctcgggcg acatctacca gggcgtcatc tcgcggaccc gcgagctgta cggcgaggtc
    15361 gatccgctcg gcttctacga ggcgctcagg gcggtgaacc catcgccgta catgtacctg
    15421 ctcggttacg acgacctgac catcgtcggc gcgagcccgg agacgctggt ctccgtggcc
    15481 ggtgaccacg tcgtctcgaa ccccatcgcg ggcacgtgcc cgcgagggaa ctccccggtc
    15541 gaggaccgcc gcctcgccgg cgagatgctc gcggacggca aggagcgcgc cgagcacacg
    15601 atgctcgttg acctggcacg caacgacgtt cgcagggtcg ccgaggccgg cagcgtccgc
    15661 gtccaggagt tcatgaacgt cctgaagtac agccacgtcc agcacatcga atcgacggtt
    15721 acgggccggc tctcgcccga gaaggacgct ttcgacgccg cccgcgcgac gttccccgcc
    15781 ggaacgctct cgggcgcacc gaagattcga gccatggaga tcatcgacga gctcgaacgc
    15841 tcgccgcgcg ggccatacgg cggcggcgtc ggctacttcg actggggcgg cgacgcagac
    15901 ttcgccatcg tcatccgctc ggccaccatc gaggacaccg acgagtccga ccgcatcacg
    15961 gtccaggccg gcgcgggcat cgtcgccgac tcggaccccg agagcgagta cgtcgagacc
    16021 gaacagaaga tggacggcgt gctgacggcg ctggagcgca tcgaggatga ccggtcgacc
    16081 gacggattcg atagaaccga cggcgacgag gccgacacga ccgacggcga cgagcacgcc
    16141 ggggaggtgc cccgatgagc gcgtcgcgac cggccggcga ggacgcggtc agggacgacc
    16201 tgcgggtcct gttcgtcgac aacttcgact cctttacgta caacctcgtg gagtacgtct
    16261 ccgaacacgc cgagaccgaa gtcgtccgga acacggcgtc gctcgacgac gtgagagcgt
    16321 tcgaccccga cgccatcgtg ctctcgcccg gcccgggtca cccgaagaac gagcgcgacg
    16381 tgggcgtcac gctcgacgtg ctccgcgaga tcagtcccga cgtgccgacc ctcggagtct
    16441 gcctcggtct cgaatcggcg gtgtacgcct acggcggcac catcggtcgc gcgccggagc
    16501 ctatccacgg caaggccttc cccatcgatc acgacggcga aggcgtcttc cgcggcctcg
    16561 aacagggctt tcagggcggg cgctatcact cgctggtcgc agagggcgtc cctgacgagt
    16621 tcgtcgtcag cgcgacgact gagacggcgg acggcacgga actggtgatg ggcgtccgtc
    16681 accgcgagca tcccatcgag gccgtccagt tccacccgga gtccgtcctg acttcggtcg
    16741 gtcacgacgt gatccggaac ttcctcgctg gactctagat aatctggaag cccagcatcc
    16801 cgagcagcca gaggacggcg acggcgacga tggcgagaac cacgattcgc cacgccattt
    16861 tcatgacgaa ccgaccgacc agcaggacga gcgcgatcac gaggaggccg cccagcagcg
    16921 cgggcagcga ggggaccccg ccgagttgca ggagccagag catacggtgg acaacgacgg
    16981 ccggcgggaa atacttcgtg gctggatcgg acgtggcggg cggtcggtcg acgcggcgaa
    17041 ttgcggcggt gcgcgggccg ccgctctatt tgggaaatcg catgactgca gtccgtctga
    17101 cgcacttgta ttcggctcct actcgccgtt agtcggcggc tatctcggtc cgaaaccccc
    17161 tgctgtttcg actggatatg tcgctcccgt ccgggggttc cgtgggagcc gatttcactt
    17221 tcactgcggt ctacacacta ttaagaagag tccggcgcat ctattccgat gtacgcgact
    17281 atcgtctccg cgtcgctcgc acagaccgac gaacaccgta gttgcgacgc tgtctcgcga
    17341 gtgcggtcgc gccgaactcg cagccaagaa ggaaggatta aacgccatcg atgaatacgt
    17401 atctgccgcc agaaatgacc ggaacacggg tagccactga acggggtatc gaccggcagc
    17461 gggccgctgc cgggcggagg aacgggcgat gagtaacagc gacctctccg ccgacgagat
    17521 cacgcttccg atcaaacgga ccgacgggga caccctcgaa gaacggctca caggcaacgc
    17581 ctaccacaac atcctcccgg cgcgctatct ccggaaggac gccaacggcg acctcgtcga
    17641 ggagcccgaa gacctcttcc agcgggtcgc gaagaacatc gcgctcgccg aggccgtctt
    17701 cgaagcgaac aagcggggcg ccgacgtgac cgtcacgccc gagcagctga agcccgacca
    17761 cccgcgccgc gacgaactcg cggccgaggt gttcgggaaa gggactgccg tcgacgacga
    17821 cgccgagacc gagctctccg tctacaacgt caacaagttc gcctacgaca ccgtcgttcc
    17881 ggagctcccc gaggaggtcc gcgaccacgt cgagtccgtc gccgacgcgt tccaggacca
    17941 gatggaacag ctctcgttca tgccgaactc gccgacgctg atgaacgccg gcgacgagct
    18001 ccagcagctc tccgcctgct tcgtcgactc gcccggcgac gacatcgacg acatccacca
    18061 gaccgccaag gaggccgcgc aggtcttcca gtccggcggt ggcatgggct acgcgttctg
    18121 gaagctccgc ccgtacggcg accccgtcgg ctccaccggc ggcatcgcct ccgggccgat
    18181 cacgttcatg cggacctacg accagatgtg cgagaccatc gcgcagggcg gggcccgccg
    18241 cggtgcacag atgggcgtca tgcgcgtctc tcaccccgac gtcatccagt tcatccacgc
    18301 caagaacaag gacgtctcgc tggccgagac gctgcgcctg aacgaccccg acgacttcac
    18361 gcacaactcc ttcgccgagg ccttagagga gtcccgcgag ctcatcgacg aggacggcaa
    18421 ggtgcccaag cacctccgca acgccgtcga gggccacctc tcgaacttca acatctccgt
    18481 cggcatcacc gacgacttca tggacgcgct ccagaacggc gaggagttca cgttcacgaa
    18541 cccccgcacc gaggagcccc acgtcgcgac cgaacagacc gaggagctct acgagatgtt
    18601 cgacctcggc gagtacgtcg aggccggcga ggtcctctcc atccccgccg agaagctctg
    18661 ggagcgcatc gtgcagggcg cccacgagaa cggcgagccg ggcgtcatct acctcgaacg
    18721 cgtcaacaag cagcactcct tcgacgtgga ggaacacccc gagcaccaga tcctcgcgac
    18781 caacccctgc ggcgagcagc ccctggaaga gtacgaggcc tgtaacctcg gccacatcaa
    18841 tctctcgacg ctggccgccc aggacgcgcc ggactggcgc gtctggtccg ccgagcacgg
    18901 cgacgagtac gactcgaccg aggcggccat cgaggcgttc ctcgaggacg caatcgactg
    18961 ggcggagttc gaccgccgca tcgaactcgg cacgcgcttc ctcgagaacg tcgtcacgat
    19021 gtcggacttc ccggtcgaga agatcgagca gaaggtccgc gagatgcgca agatcggcct
    19081 cggcatcatg gggctggccc agctgtacat ccagctcggc gtcgcctacg gcaccgacga
    19141 ggccaacgag atcgcccggc agacgatgcg ccacatcaac cacggctcga aggccaccag
    19201 ccacgaactc gccgaggacc gcggcgtctt cgaggagtgg gacaactcca agtacgcgac
    19261 cccgaccgag taccgcgagt ggttcgagaa gcagaccggc gaggacgccg acgactggga
    19321 agacggctac cccatccgca accacaacac gacgaccatc gcgccgacgg gcacgacctc
    19381 gatgatcggc aacaccaccg gcggctgtga gccgatctac aacgtcgcct actacaagaa
    19441 cgtctccgac gacgtgcagg gcgacgagat gctcgtcgag ttcgacgact acttcctgcg
    19501 cgccctggag gacaacgaca tcgacgtcga cgccgtcaag gaggaggccc aggaacagat
    19561 ggcgaacaac gagttcgacg gcgtcgacgg gctcacgacg gtcccggacg ccatcggcga
    19621 actgttcgtc acgacgggcg acctctcggc gcgacagcac gccggcattc aggtggcctg
    19681 ccaggagggc gtcgactccg ccatctcgaa gacggtcaac gcccccaacg actccaccat
    19741 cgaggacgcc gccgcggtgt tcgagtacat ctacgaccac ggcggcaagg gcgtcaccta
    19801 ctaccgcgac ggcacccgct cgaagcaggt gctgacgacg cgcgcccaga acacggagtt
    19861 cgccgacatg gacgccgagg aggtcgtcgc ccagatcgag gaggtcttcg gcggcatcga
    19921 gggcttcctc gaagacgagg ccgtccgggc cgctatcgac gactccgtcg cggagattct
    19981 gagcgtcgca gacggcgacg cggatgccga gttcgccaag aagcagtccc ggccggacgt
    20041 gctccacggc gtcacccagc gcatcgacac cggctacggg aagctgtacg tcaacatcaa
    20101 cgaggacccc gaggccgacc ggccgttcga gctgttcgcc aacatcggca actccggcgg
    20161 tttcacggcc tcgttcaccg aggccctggc caagaccatc tcgaccgcgc tccgctcggg
    20221 cgtcgacccc gaggagatcg ccgacgagct ccagggcatc cggtcgccga aggtcgcctg
    20281 ggacaagggc gagcagatcc agtccatccc ggacgccatc gggacggccc tgc
//
