LOCUS       NZ_WRXL01000001        20297 bp    DNA     linear   CON 23-OCT-2024
DEFINITION  Haloarcula salina strain YGHS18 scaffold1, whole genome shotgun
            sequence.
ACCESSION   NZ_WRXL01000001
VERSION     NZ_WRXL01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Haloarcula salina
  ORGANISM  Haloarcula salina
            Archaea; Methanobacteriati; Methanobacteriota; Stenosarchaea group;
            Halobacteria; Halobacteriales; Haloarculaceae; Haloarcula.
REFERENCE   1  (bases 1 to 954375)
  AUTHORS   Zhang,W.J. and Cui,H.L.
  TITLE     Halomicroarcula salina sp. nov., isolated from a marine solar
            saltern
  JOURNAL   Int J Syst Evol Microbiol 65 (Pt 5), 1628-1633 (2015)
   PUBMED   25721722
REFERENCE   2  (bases 1 to 954375)
  AUTHORS   Zhang,W.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-DEC-2019) Department of Biology, Anhui Normal
            University, No. 1 Beijing East Road, Wuhu, Anhui 241000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.9.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_010119195.1-RS_2024_10_23
            Annotation Date                   :: 10/23/2024 11:42:32
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,870
            CDSs (total)                      :: 3,820
            Genes (coding)                    :: 3,795
            CDSs (with protein)               :: 3,795
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 44
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 25
            CDSs (without protein)            :: 25
            Pseudo Genes (ambiguous residues) :: 0 of 25
            Pseudo Genes (frameshifted)       :: 11 of 25
            Pseudo Genes (incomplete)         :: 16 of 25
            Pseudo Genes (internal stop)      :: 5 of 25
            Pseudo Genes (multiple problems)  :: 6 of 25
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:19:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 341201
            Orig. end                         :: 361498
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            WRXL01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20297
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="3"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..20297
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20297
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10297](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10297
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     gene            488..1456
                     /locus_tag="GM656_RS01855"
     CDS             488..1456
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008309520.1"
                     /locus_tag="GM656_RS01855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="WP_162411950.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 4.4e-12, bitscore:
                     42.5, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAIVLAGGYATRLWPVTKHRPKMLLPVGDTTVIDRVLGELEADD
                     RISDVFVSTNQRFADDFREHIAASSFEKPILTVEETAEEDEKFGVVGALAQLVDREDLG
                     DEDLLVVAGDNLISFDIAEFIDYFEQYDDPTLAAYDVGSREKAKSYGLIELDGDEVVDF
                     QEKPEDPNSTLVSIACYAFPADSIRFDEYLEAGNNPDEPGWFIQWLVDDGPVRAFTFDD
                     AWYDIGTPESYLEAVAWELDGDNVVAEDATIENTTLGENVHVLPGSEIVNSSLDRTIVF
                     PDTTIVDSDIRQSIIDRDTQVESLDLAGALIGAHTQLTNGN"
     gene            complement(1496..>1621)
                     /locus_tag="GM656_RS01860"
                     /pseudo=""
     CDS             complement(1496..>1621)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004593002.1"
                     /locus_tag="GM656_RS01860"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="GGEFETLVTDGPHMDRRIELAYETEWDGTRGTIRVEDAWLA"
     gene            1868..2053
                     /locus_tag="GM656_RS01865"
     CDS             1868..2053
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GM656_RS01865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_162411951.1"
                     /transl_table=11
                     /translation="MDRTDWFLAFITFLLAVITLETVSNATNELFREIGGGASIVVIYF
                     LPLYLLGHAVMNRSDD"
     misc_feature    1907..1909
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(2110..2829)
                     /locus_tag="GM656_RS01870"
     CDS             complement(2110..2829)
                     /EC_number="6.3.1.14"
                     /GO_function="GO:0017178 - diphthine-ammonia ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004593002.1"
                     /locus_tag="GM656_RS01870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="diphthine--ammonia ligase"
                     /protein_id="WP_162411952.1"
                     /transl_table=11
                     /translation="MTDGAWVSLFSGGKDSSWALYRALERGYPVERLVTVHPDGDSYMY
                     HVPATRLASLAAESVGVPLVEVEPDDFDADDVPDSGAQGDAELEPLEAALRDLDAELDG
                     GIGGVTAGAVESEYQTTRIEAMAERLEANVFAPLWQENPRDLADAMLDAGFEIRIVRVA
                     AYGLDESWLGRTLDADALDELEALHDEYGVHILGEGGEFETLVTDGPHMDRRIELAYET
                     EWDGTRGTIRVTDAWLA"
     gene            complement(2865..3986)
                     /locus_tag="GM656_RS01875"
     CDS             complement(2865..3986)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014040162.1"
                     /locus_tag="GM656_RS01875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF373 family protein"
                     /protein_id="WP_162411953.1"
                     /transl_table=11
                     /translation="MSTLVVCIDRDGPDTSGYPVVGRSDVESLITRTGVVDPEDSRVNC
                     LLEGLSVAAELDDDGSEPVVAVVGGGSDSVGSDREIAAQIDALVAEYDPDSAVVVVDSA
                     EDERLVPIVESRVDVDAVDRVVVRQARDIESTYYLLKQFLADEELRKTVLVPVGIVMLA
                     FPILLVVTSLTLAVGAIAAAIGVFLIYKGLGIDTYLSRLPGQIREALYSGQVSLVTYVV
                     AAGLSLVGIFAGVLGVSATGDISPFLLANRFAFGSVPWLTGAALVASLGRLLDELLKRE
                     GVRSAYVNLPFGAVAVGLVVRGFSAYFLERGGVFAPFRVTPTDLGVVQIQGFSLDPGTR
                     LALFILAGILISLVGVRVATYVSHTDIEEELVE"
     gene            complement(4031..5026)
                     /gene="sppA"
                     /locus_tag="GM656_RS01880"
     CDS             complement(4031..5026)
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sppA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014040161.1"
                     /locus_tag="GM656_RS01880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="signal peptide peptidase SppA"
                     /protein_id="WP_162411954.1"
                     /transl_table=11
                     /translation="MVDADDVVRGLLVVGIALVAAVVGWILFVRVPTDLAGLLGVLLVL
                     AVVVGAVRVGGRVAGSLFPAHNVAEVAVEGPITRDGGGGLTSPPVGAQADDIVEQIERA
                     DEDRGSRALLLKLNTPGGEIVPSEDIRLAAERFDGPTIAYATDVCASGGYDIAAGCDEL
                     WAREGSIVGSIGVIGSRVNAEELADRLGLSYEQFTAGEYKDAGVPLKEMREDEREYLQG
                     IVDEYYDQFVETVAEGREMDAEALRETEARIYLGETAAEKGLVDELGTREDLETSLEQR
                     LGEPVRIQEYEASRGLAGKLRGSAQRVAFAFGAGVASAFDGDIDGLSFRR"
     gene            complement(5026..5763)
                     /locus_tag="GM656_RS01885"
     CDS             complement(5026..5763)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008309526.1"
                     /locus_tag="GM656_RS01885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="proteasome assembly chaperone family protein"
                     /protein_id="WP_162411955.1"
                     /transl_table=11
                     /translation="MAHVQIHRDDISLESPTLVEGLPGVGLVGKIAADHLIDAYDMEYY
                     ASAHCEGLPEIAVYGADDPEVRPPVRFYADAERDLLVLQSDAPVSPSAAKEFAGCMVGW
                     FRDHDVTPVFLSGRPAEKEGVPAVYGVSTGDGASMLEEADIDPPSEMGAITGPTGALIH
                     ESQRVGLTGVGLVVEADRQFPDPEAARALLQTAIGPLADFEVDTEALVEQAEEIGKAKE
                     RLAQQLQEDQDDSTSARPLGMYQ"
     misc_feature    complement(5185..5187)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            5850..6761
                     /locus_tag="GM656_RS01890"
     CDS             5850..6761
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008309528.1"
                     /locus_tag="GM656_RS01890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="WP_162411956.1"
                     /transl_table=11
                     /translation="MEPLERYRPIVDDFEAFRAACERPLPSAVRVNTIKATAERVRRAL
                     DEADIAYDPVDWHDGLFVLPEDSPGANWPYFHGWIHGQEEVSAVPATVLDPQPGERVWD
                     ACAAPGSKTTQLAALMDDDGEIVATDNNLGRISALRTNTERLGATSIAVTHEDARNHSL
                     KPFGGESYDRALVDVPCSCEGTIRKNPDTFEDWTLSHVEGIAGVQKGVLKRAVEATAPG
                     GTVVYSTCTFAPEENEAVLDFALDEAACELVEYDLPLAHRPGVTEWQDETFDPSVRTAK
                     RIYPHHNDTGGFFCAKLEVTGE"
     gene            6758..7258
                     /locus_tag="GM656_RS01895"
     CDS             6758..7258
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008309530.1"
                     /locus_tag="GM656_RS01895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_162411957.1"
                     /transl_table=11
                     /translation="MTDESTTFTRLPATADEREDPERATRAEVLDFWDERFGVAPETFA
                     DYTFWERGAGKLWLYRGDPPSPVDVEGLGMTFLRTRQEHWKPTLEAAQRFGAHATENVI
                     HLDDEAARAFVAGEDRERDWDGDWGYLIVTHDIAGAVEPVGVGLYVYGELRSQVPKGRR
                     REV"
     gene            7357..8028
                     /locus_tag="GM656_RS01900"
     CDS             7357..8028
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GM656_RS01900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_162411958.1"
                     /transl_table=11
                     /translation="MQGGVCGIVDGTFDVVGPYTETETEREHELSRSVQVDRVFSLPSG
                     KPGFEGHAAAERLVTRSDTEIRDGEIRVTESTVKETVRTAFAGVPGEVVVAESGGGEFA
                     FDLIGAETDTAIERGAFDLSGFLDAHRSGSPWKAGFYDADGHAQKGTVYGDDLLRDDAF
                     EPVLDTASLNQLGIDYEYRGRTVKVDLTESGFVTVHRPSGMDTAAFLEFLIADVLPHST
                     G"
     misc_feature    7855..7857
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(8082..9884)
                     /locus_tag="GM656_RS01905"
     CDS             complement(8082..9884)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006184762.1"
                     /locus_tag="GM656_RS01905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_206673689.1"
                     /transl_table=11
                     /translation="MAELELPRGERYRSLRRVALHRPLLTSGIVATSLVAMALEGIGLS
                     FLFPVIEAAQTGGALSTAEGGIAGRLLSVYAAVGLPLTLEFLLLGLGCVMTCRYASAFA
                     VKWLAAKLTKGYERALKDRAYELALGASVAYYDEEGSDDVLNAVLTQTRYAGRVIGRIV
                     QFFQQGLLCVAYAAIALAIAPLLTMAAAVALGGLTVLFRYGIEPGYAVGDRVATANEQL
                     QETAQAGTQGVRDVKLFGMRSDLLSEFRATLDRYATTSVAVRRNEVAIQSFYQLAVSLA
                     LFGLVYVAIRYRALSVSALGVFLFAMFRLAPRLSSLNATVYAIEGELPHLVRTHRFIDQ
                     LADRQEETAGAAVPERIDEIRFENVSFAYDDERVLDDLSMEIEGGEFVGVVGPSGGGKS
                     TVVSLLARLYGPDDGAILANGESIQTYDLRAWRETVAMVRQDPHIFDDTLRYNLTAGRS
                     VSERDLRDAAETALVTEFLDDLPRGFDTVLGDDGVKLSGGQRQRVALARALLTDAPVLV
                     LDEATSDLDTALERRVHRAVETLDGDRTVVAIAHRLSTVANADRIYTVEDGRVSETGTH
                     SSLTARDGTYAELYAMQRSERVES"
     gene            10001..10297
                     /locus_tag="GM656_RS01910"
     CDS             10001..10297
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004516899.1"
                     /locus_tag="GM656_RS01910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PqqD family protein"
                     /protein_id="WP_162411959.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 7.5e-30,
                     bitscore: 98.8, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 7.9e-17, bitscore: 57.3,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTIETGTTVVATDDCVATAVDDEVIVLNSETGMYQGLTGVGPDI
                     WRLVQEPTEFDEIVSALVAEYDVDRARCASDVSDFLETLATSRLVETDANAAR"
     aSDomain        10025..10276
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_GM656_RS01910_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="2.10E-31"
                     /identifier="RREFam002.1"
                     /label="GM656_RS01910"
                     /locus_tag="GM656_RS01910"
                     /protein_end="92"
                     /protein_start="8"
                     /score="98.8"
                     /tool="antismash"
                     /translation="TVVATDDCVATAVDDEVIVLNSETGMYQGLTGVGPDIWRLVQEPT
                     EFDEIVSALVAEYDVDRARCASDVSDFLETLATSRLVET"
     gene            10278..10718
                     /locus_tag="GM656_RS01915"
     CDS             10278..10718
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF13471"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF033537.1"
                     /locus_tag="GM656_RS01915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_162411960.1"
                     /sec_met_domain="PF13471 (E-value: 1.5e-21, bitscore: 72.6,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTLLGEVLSQSSSRRRLLCGTAMLIVSSKVLLALVGLDRSVRWV
                     GYLGRVSPPYRPVESVEQIPWSIDTVAARLPGEFDCLDRAVAGNALLAASGYRGRIRLG
                     VDKRDDAFEAHAWIEWNDEVLIGDLDDLDRFRTLPESEVAPF"
     gene            11253..12167
                     /locus_tag="GM656_RS01920"
     CDS             11253..12167
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008309540.1"
                     /locus_tag="GM656_RS01920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_162411961.1"
                     /transl_table=11
                     /translation="MAVATTETYEAFGLTVRSEIDLPELSTADPGGPTDPDVTVTVRTL
                     TRPPALTSETSFHAAGQRDYYLQYDAATVRVRDGTRIAVDPARGVPHEVLRHVIVGPAL
                     NHLLHQRGYFVLHASTVSIDGAAVAFVGESGQGKTTTAMACLTEGHHVLSDDVAAITLD
                     GGTPVVRSGYPAVKLSTEAVETFDPPVEPPVRTCDGRPRHFHRLRHDQPASPVPLAGVY
                     LLEDGPEIEVESLSGGERIMSLVDNTYAIGTLGSDGQAATNVGVCGEIAGATSVKRLRR
                     PRDLDRLPEVIDRVRADIAGERC"
     misc_feature    11904..11906
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12161..13384
                     /locus_tag="GM656_RS01925"
     CDS             12161..13384
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005534794.1"
                     /locus_tag="GM656_RS01925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_162411962.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 1.3e-63, bitscore:
                     210.8, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSDAEPELRLVIECVRAAVDPGADPDIEPLVSSDLDWDRVLDLA
                     RYHGVLQLLQQGLASTYREVKQERGVPPSVSSRLDGTVQRRTMRNLAATDELRGILDDF
                     DDANVRALPFKGPVLSAFAYDSVTVREYNDLDFLVHPEDVSTAADVLEERGYEWRDGAP
                     RLDDAALLGGSATKAIVHEYAMTGSDIDVELRWRVGDAERPFSPDVTALWDHREQVDVG
                     GASVPALAPEDRLLVLAFHGTKHRWYLLKWLCDFVAAMDATTADWDRVLARARDHGVER
                     PFLVGAALAGSVFEYGLPEPVATRVSEASGVTGLADRVRRSLASGSMSAPGRIESARFF
                     AAASESPTALLRLVALHSALHPTYADYRFHPLPGHLHPLYYVVWPLRLLAGLLPDRTET
                     DPPTEEPT"
     misc_feature    13334..13336
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(13395..14969)
                     /locus_tag="GM656_RS01930"
     CDS             complement(13395..14969)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007189858.1"
                     /locus_tag="GM656_RS01930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF790 family protein"
                     /protein_id="WP_162411963.1"
                     /transl_table=11
                     /translation="MLTKDLLRVSRAGGGYHLRFADDDAERLAARVLGVYQGHVGESRA
                     DLQAALADLEREADDFKLVRGFAKLVEREATFETRAPVDPERARRRVFEAAERVGVVSE
                     AERDRAVADAADHFGTDASTLADALYADRESKQVLTAVDSRWGPAELRTQYDLSLAQTA
                     LFDATEVRVRSSDPKALVSAVKRLRLMYEIRRTDRGREVVVTGPDALFSNTRRYGTRFA
                     RLLRTVAAADEWDLVATIDDRGTERELTLSDADVSVPGVDPVTEVSYDSGVEADFAARF
                     AALDLDWDLIREPEPLAAGEHVVIPDFAFEWRPGTDGGVRETFRDAGERAAGDGPDDPP
                     FRVFFEIMGFWTPEYVAKKLDRLGDLEDVAMLVAVDESLGVGDAVEATDNRAIPYSGTV
                     RVKDVRDALRPYEDRLVSESAAAIPDEVRPDAAVVSLADLAADYGVSEDALADAAFPDH
                     ERVGRTLVRPSVLDELADDIEAGMAYETAADRLADYGIADDSAALSRLGYRVAWEGLGG
                     GTIQPRD"
     gene            complement(15045..16319)
                     /locus_tag="GM656_RS01935"
     CDS             complement(15045..16319)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007261365.1"
                     /locus_tag="GM656_RS01935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TIGR00341 family protein"
                     /protein_id="WP_162411964.1"
                     /transl_table=11
                     /translation="MRLIHIRVTEDELDDVRAVLDDRDISFVRTVEESADETAFLLQFP
                     LPPEAIDEVLAEMEAAGLDTDRYAVVGTAETARPDQSNSARNYDDRISHDELRGRARGM
                     NPGKATYYGMTILSAIVATAGLLLDSPAVVVGSMVIAPQVGSALIASVGTALSDRELIV
                     EGVRDQLLGLVVAVASAAVFGLFIRYSGFVPARLRVTTVQQIAQRISPGFLSMAVGLCA
                     GAAGAFGLATALPVSLVGVMIAAALIPAAAAVGVGIAWGLPAVALGAGILLVVNVTSIN
                     LTGFLVLWWLGFRPLDWEADASPAEAVRAHAPTAIAVLLLLVAFAGAGTVTAQQMQVET
                     AVNAAVTETLSDDAYAELRLLSVQTRFGGVTVYRLDREVSVAVSRPAERGYPGLVGDLE
                     RAIGRSIEDEVAVTVTFEDRASTPR"
     gene            complement(16449..17783)
                     /locus_tag="GM656_RS01940"
     CDS             complement(16449..17783)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1122: ATP-dependent
                     RNA helicase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004593010.1"
                     /locus_tag="GM656_RS01940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="WP_162411965.1"
                     /transl_table=11
                     /translation="MLELTFESGTIRVSGSPPTDLPGVERDERSQSARAPAYRYADLVT
                     ALDERGVAYADRVGPLPPVSLSTTYDLREYQQSALDAWRAAGDRGCLELPTGSGKTVIG
                     IAAMVALGTPTLVVVPTIDLLEQWQRELEREFDRPVGRMGGGEQRVEDVTVSTYDSAYL
                     RADELGDRFGLVVFDEVHHLGGEGYRDIARLLAAPARLGLTATFERPDGAHDVIEGLVG
                     PLVQRVGVDDLAGEHLADYDIKRIEVSLTPEERERYEDEQGTFTDYLQRSNIQLRSGSD
                     YQELVKRSGTDPAAREALLAKQRAREVMMNAERKVDRLAEILDRHRGDRVIVFTAFTDL
                     VYRLSERFLVPAITHETGASERREILERFRDGSYSRVVTANVLDEGVDVPDANVAVVLS
                     GSGSEREFTQRLGRILRPKDDGSRALLYELVTEETAEERVARRRR"
     gene            17929..19029
                     /locus_tag="GM656_RS01945"
     CDS             17929..19029
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007189861.1"
                     /locus_tag="GM656_RS01945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="WP_162411966.1"
                     /transl_table=11
                     /translation="MTPTRSTLLALLVSLSLVLATVPAGVTAIQMTDTQTATDTLTVDR
                     DGSADYRSIQAAVDAADSGDTVAVRPGVYYEQITVAENVTLVAPDRAILDGSRFVNGTA
                     LRVTGAAAPNVTGFTMRNYRLGVVANDTTGDWTLRDSTVIRASVGVYAPNASGNWTIAD
                     SAVSSTTYSGVFARATTGEWTIRDTRFVEVGGDGVDVRRSTGDWTVSDIVVDRSGADGV
                     DASGTTGDWTVRNTTVRRSDTGVKAIASRGDWTVTDLTVQRSDTGLVTASTSGDWTVSD
                     ATVTTREIGVFTARTTGAWTIRNSTIDSRFQGIHAAGTNGSWTVSDSSITVSGNADAIG
                     VDARDAAEGWSLDSVDIQSTGVDVAE"
     tRNA            19114..19184
                     /anticodon=(pos:360347..360349,aa:Pro,seq:ggg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="GM656_RS01950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /product="tRNA-Pro"
     gene            19114..19184
                     /locus_tag="GM656_RS01950"
     gene            19442..19627
                     /locus_tag="GM656_RS01955"
     CDS             19442..19627
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GM656_RS01955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_162411967.1"
                     /transl_table=11
                     /translation="MSRSVSEKLGEGWRMMCPENHHTLEDQVGPTVYCEQCNCAYRYDD
                     LIDKAELGSGKRGYRH"
     gene            complement(19782..20171)
                     /locus_tag="GM656_RS01960"
     CDS             complement(19782..20171)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GM656_RS01960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_162411968.1"
                     /transl_table=11
                     /translation="MASNRRAEASETNRLTEDQIFSLLSNRRRRDLLRFVESVGGESAV
                     PAITDHLAQSEYGGADVSASQRKNVYVSLHQTHLPKLADAGVVEYDEQTKRVALTDRAV
                     LLLAYCHFDPSSRGGLLSRLFPNGR"
     misc_feature    complement(19950..19952)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 cgtcggagcg ccgtcccctg catggactcg aactcgaccc cctgcccgcc gccgggcagc
       61 gcccagaggt cggccccgcg gccgagcacc agcagcgctc ggtcccgggc gtcggccgcc
      121 gcctgctcgg gcaggttctc gctgatctcg ggaaactcgt cggcagacct gacggggaag
      181 acgacgctgt tctcggcgaa gccggtcccc tgcgtggccg cgaacacgtc ggtgtactcc
      241 tccgccgaga ggtggaacgt ccgctccgtg accgggacct cgtcgaaggc ggcttcgagg
      301 tcggcgatcc gccgttcgac ggaggtctgg ttgaccatct cgatgtagtt ctccgccggc
      361 acggtcgact cgtcgctctc cggtgcgtcc tcctcagtca tacaggaacg ttcacggggg
      421 aaccgataaa tggcgcgatg gcgagggcat gaaaaagaac ttgtattccg cttgtctcta
      481 atcgaacatg aaagcgatcg ttctcgcggg agggtacgcg acgcggctct ggcccgtcac
      541 caagcaccga ccgaagatgc tgcttccggt gggcgacacg acggtcatcg accgcgtcct
      601 cggcgaactg gaggccgacg accggatctc ggacgtgttc gtcagcacga accagcgctt
      661 cgccgacgac ttccgcgagc acatcgctgc cagcagcttc gagaaaccga tcctcaccgt
      721 cgaggagacc gccgaggagg acgagaagtt cggcgtcgtc ggcgcgctgg cccagctcgt
      781 cgaccgcgag gacctcggcg acgaggacct gctcgtcgtc gccggcgaca acctcatcag
      841 tttcgacatc gccgagttca tcgactactt cgagcagtac gacgacccga cgctcgccgc
      901 ctacgacgtg ggctctcgcg agaaggcgaa gtcctacggc ctcatcgaac tggacggcga
      961 cgaggtcgtc gacttccagg agaagcccga ggaccccaac agcacgctcg tctccatcgc
     1021 ctgctacgcc ttcccggccg attcgatccg cttcgacgag tacctcgagg ccgggaacaa
     1081 ccccgacgag cccggctggt tcatccagtg gctcgtcgac gacggtcccg tccgcgcctt
     1141 taccttcgac gacgcgtggt acgacatcgg cacgcccgag agctacctcg aagccgtcgc
     1201 ctgggaactc gacggcgaca acgtcgtcgc cgaggacgca accatcgaga acaccaccct
     1261 cggcgagaac gtccacgtcc tcccggggag cgagatcgtc aactcaagcc tcgaccggac
     1321 catcgtcttc ccggacacga ccatcgtcga ctcggacatc cgtcagtcga tcatcgaccg
     1381 cgacacgcag gtcgagagcc tcgacctggc cggcgcgctc atcggcgcgc acacgcaact
     1441 gaccaacggg aactgacggc agaccgcgtc ttcggaatcc gttttgttct ctgtctcagg
     1501 ccagccaggc gtcctcgacg cggatcgtgc cccgagtccc gtcccactcc gtctcgtacg
     1561 ccagttcgat ccggcggtcc atgtgcggcc cgtcggtcac cagcgtctcg aattccccgc
     1621 cgtacctttt tcatcgtcgg gtttcctcgc gccgttggcg ctgcgggaat cactcgatgt
     1681 aaaatctacg ctaaaaagcc cgccctcact tcgttcggcc gggtgaatcg gctcgccgcg
     1741 ctcgccgaat gcgatcagtc gttgtgaata cggtttttat tcatcagagg agtgaaatga
     1801 ctgctcggta agtgtgctta tttactgaat cagaagttta taatggaatg aaatgatcat
     1861 attgtgtatg gatagaaccg attggttcct cgcattcatc acttttttat tggctgtaat
     1921 cactcttgaa accgtctcaa atgctacgaa cgaactcttt cgagagattg gaggtggtgc
     1981 ctcaatagtg gtaatctact tcttgccact ctatcttctt ggccacgctg tgatgaaccg
     2041 aagtgatgat tgaatctcct gtactgacca ctacgatcgt gtatagattc gctgtattca
     2101 caacaactgc tatgccagcc acgcgtcggt gacgcggatc gtgccccgag tcccgtccca
     2161 ctccgtctcg tacgccagtt cgatccggcg gtccatgtgc ggcccgtcgg tcaccagcgt
     2221 ctcgaattcc ccgccttcgc cgaggatgtg aaccccgtac tcatcgtgga gggcttcgag
     2281 ttcgtcgagg gcgtcggcgt ccagcgtccg gccgagccag gactcgtcga ggccgtaggc
     2341 ggcgacgcgg acgatgcgga tctcgaaccc ggcgtcgagc atcgcgtcgg cgaggtcgcg
     2401 ggggttctcc tgccagagcg gggcgaagac gttcgcttcg aggcgctcgg ccatcgcctc
     2461 gatgcgggtc gtctggtact cgctctcgac cgcgccggcg gtgacgccgc cgatgccgcc
     2521 gtccagttcc gcatcgaggt cccgcagcgc ggcctccagc ggttcgagtt cggcgtcgcc
     2581 ctgcgcaccc gaatcgggca cgtcgtcggc gtcgaagtcg tcgggttcga cctcgacgag
     2641 cgggacgccg acgctctcgg cggcgagcga ggccagccgc gtcgccggga cgtggtacat
     2701 gtaggagtcg ccgtcggggt ggaccgtcac cagccgctcg accggatagc cgcgttcgag
     2761 ggcccggtac agcgcccacg aggagtcttt ccccccggag aacagcgaga cccacgcgcc
     2821 gtctgtcatg cgcgccggta gccgccggcc gcctaaatcg ctgtctattc caccagttct
     2881 tcctcgatgt cggtgtggct gacgtacgtc gcgacgcgga cgccgacgag gctgatgagg
     2941 atgccggcga ggatgaacag cgcgagacgc gtcccgggat cgagggagaa cccctgaatc
     3001 tgaacgacac cgaggtccgt cggggtgacg cgaaacgggg cgaagacgcc gccgcgttcg
     3061 aggaagtacg ccgagaagcc gcggacgacg aggccgacgg cgaccgcacc gaaagggagg
     3121 ttcacgtacg cgctccgaac gccctcccgc ttgaggagtt cgtcgaggag gcggccgagc
     3181 gaggcgacga gcgccgcccc ggtcagccac gggaccgagc cgaaggcgaa tcggttcgcc
     3241 agcaggaacg ggctgatgtc gcccgtcgcc gagacgccga ggacgccggc gaagattccc
     3301 accagcgaga ggccggccgc gacgacgtag gtcacgagcg acacctgccc ggagtacagc
     3361 gcctcgcgga tctgtccggg gagccgggag aggtacgtgt cgatcccgag gcccttgtag
     3421 atgaggaaca cgccgatggc ggccgcgatc gcgccgacgg ccagcgtcag gctggtgacg
     3481 acgaggagga tcgggaacgc gagcatgacg attccgacgg ggaccagcac ggtctttcgg
     3541 agttcctcgt cggcgaggaa ctgcttcagc aggtagtacg tggactcgat gtcgcgggcc
     3601 tggcgcacga cgacgcggtc gacggcgtca acgtcgacgc ggctctcgac gatggggacg
     3661 agccgctcgt cttcggcgct gtcgacgacg acgacggccg agtcgggatc gtactccgcc
     3721 acgagcgcgt cgatctgggc cgcgatctcc cggtcagagc cgacgctgtc gctgccgccg
     3781 ccgacgacag cgacgaccgg ttcggacccg tcgtcgtcga gttccgcggc gacgctgagc
     3841 ccctcgagga ggcagttgac ccggctgtct tccgggtcga cgacgccggt ccgggtgatg
     3901 agcgactcga cgtcgctgcg gccgacgacc gggtacccgg aggtatccgg cccgtccctg
     3961 tcgatacaca ccaccagcgt ggacacacgt tcgggaaggc ggtccccgaa taaaaaacct
     4021 cccgaggcgg tcaccgacgg aaggagaggc cgtcgatgtc gccgtcgaag gcactggcga
     4081 cccccgcgcc gaacgcgaag gcgacgcgct gtgcgctgcc acggagcttg cccgcgaggc
     4141 cgcgactcgc ctcgtactcc tggattctga ccggctcacc gaggcgctgt tccaggctcg
     4201 tctccaggtc ctcgcgcgtc ccgagttcgt cgacgagtcc cttctcggcg gccgtctcgc
     4261 ccaggtagat ccgtgcctcg gtctcgcgga gcgcctcggc gtccatctcg cggccctcgg
     4321 cgaccgtctc gacgaactgg tcgtagtact cgtcgacgat gccctggagg tactcgcgct
     4381 cgtcctcgcg catctccttc aacggcacgc cggcgtcctt gtactcaccg gcggtgaact
     4441 gctcgtagga gagccccagc cggtcggcga gctcctcggc gttgacgcgc gagccgatga
     4501 cgccgatgga gccgacgatg gacccctcgc gggcccacag ttcgtcacag cccgcggcga
     4561 tgtcgtagcc gccgctcgcg cacacgtccg tggcgtaggc gatcgtcggg ccgtcgaagc
     4621 gctcggcggc cagccggatg tcttcgctgg ggacgatctc gccgccgggc gtgttcagtt
     4681 tcagcaggag cgcccgggag ccgcggtcct cgtcggcgcg ctcgatctgc tcgacgatgt
     4741 cgtcggcctg cgcgccgacc ggcggactcg tcaggccccc gccgccgtcc cgcgtgatcg
     4801 gtccctcgac ggcgacctcc gcgacgttgt gcgcggggaa cagcgagccg gcgactcgcc
     4861 cgccgacccg caccgcaccg acaacgacgg cgagcaccag caggacgccg agcagtccgg
     4921 cgaggtcagt cgggacgcga acgaacagga tccagccgac gactgcggcc acgagcgcga
     4981 tccccaccac caggagaccg cgaacgacgt cgtctgcgtc gaccattatt ggtacatgcc
     5041 gagcggccgg gcgctcgtgc tgtcgtcctg gtcttcctgc aactgctggg cgaggcgctc
     5101 tttggccttg ccgatctcct cggcctgttc gaccagcgcc tcggtgtcga cctcgaagtc
     5161 ggccagcggg ccgatcgccg tctgtaagag cgcccgcgcc gcctccgggt cggggaactg
     5221 ccggtcggcc tcgacgacga ggccgacgcc ggtcagtccg acgcgctgtg actcgtggat
     5281 gagcgccccc gtgggaccgg tgatcgcccc catctccgac ggcgggtcga tgtcggcctc
     5341 ctcgagcatc gaggccccgt cgccggtcga gacgccgtag accgccggga cgccctcctt
     5401 ctccgccggc cgcccgctga ggaagaccgg cgtcacgtcg tggtcacgga accagccgac
     5461 catacacccg gcgaactcct tggcggccga aggcgacacc ggtgcgtcgc tctgcaggac
     5521 gagcaggtcc cgctccgcgt ccgcgtagaa ccgcaccggc ggccggacct ccgggtcgtc
     5581 ggccccgtag accgcgatct ccggcagtcc ctcgcagtgt gcggacgcgt agtactccat
     5641 gtcgtacgcg tcgatgaggt gatccgcggc gatcttcccg acgaggccga cgccggggag
     5701 tccctcgacc agtgtgggcg actcgagcga gatgtcgtcg cgatggatct gtacgtgtgc
     5761 catgtccgta tttcgctcgc gagtggcttg aaggtcgggg gacgccggcg ttcgaaacgc
     5821 acaagcgcgc cgccggccaa cgccggacaa tggaaccact cgagcgctat cggcccatcg
     5881 tcgacgactt cgaggcgttc cgggcggcgt gcgagcgccc gctgccgtcg gccgtccggg
     5941 tcaacacgat caaggccacc gccgagcgcg ttcgccgagc cctcgacgag gcggacatcg
     6001 cgtacgaccc cgtcgactgg cacgacggcc tgttcgtcct gcccgaggac tcgcccggcg
     6061 cgaactggcc gtacttccac ggctggatcc acggccagga ggaggtctct gccgttccgg
     6121 caaccgtcct cgacccccaa cccggcgagc gcgtctggga cgcctgcgcc gcgccgggca
     6181 gcaagacgac ccaactggcc gcgctgatgg acgacgacgg cgagatcgta gcgaccgaca
     6241 acaacctcgg gcgcatctcc gcgctgcgga ccaacacgga gcggctgggc gcgacgagca
     6301 tcgccgtcac ccacgaagac gcccgcaacc actcgctcaa gcccttcggt ggcgagagtt
     6361 acgaccgcgc gctcgtggac gtaccctgct cctgtgaggg gacgatccgg aagaatcccg
     6421 acaccttcga ggattggacg ctctcgcacg tcgagggcat cgccggcgtc cagaagggag
     6481 ttctcaagcg cgccgtcgag gccacggccc ccggcgggac cgtcgtctac tcgacctgca
     6541 ccttcgcccc cgaggagaac gaggccgtgc ttgacttcgc cctcgacgaa gcggcctgtg
     6601 aactggtcga gtacgacctc ccgctcgccc accggccggg cgtcaccgag tggcaggacg
     6661 agacgttcga cccgagcgtc cggacggcaa agcgaatcta cccgcaccac aacgacacgg
     6721 gcgggttctt ctgtgcgaaa ctggaggtga ccggcgaatg accgacgaga gcacgacgtt
     6781 cacccgactg cccgcgacag ccgacgagcg cgaggacccc gagcgggcga cccgcgccga
     6841 ggtgctcgat ttctgggacg agcgcttcgg cgtcgccccc gagacgttcg ctgactacac
     6901 gttctgggag cgcggcgcgg gcaaactgtg gctctaccgc ggcgacccgc cctcgcccgt
     6961 ggacgtcgag gggctgggga tgacgttcct ccgcacgcgc caggaacact ggaagccgac
     7021 gctggaggcc gcccagcgct tcggagcgca cgccacggag aacgtgatcc acctcgacga
     7081 cgaggcggcg cgcgcgttcg tcgccggcga ggaccgggag cgcgactggg acggcgactg
     7141 gggctacttg atcgtcaccc acgacatcgc cggcgcggtc gaaccggtcg gcgtcgggct
     7201 gtacgtctac ggcgaactcc gctcacaggt cccgaaaggg cgtcgccgcg aggtctgaag
     7261 ccgacacctc gcctcggacg agtgtttatt ttacaaacag aatcactaca gaatagttat
     7321 aatcaagcta agtagtgcga ttacggttcg tgaagtatgc aaggaggcgt ctgtgggatc
     7381 gtcgacggga cgttcgacgt tgtggggccc tacaccgaga cggaaacgga gcgggaacac
     7441 gagctttcgc gatcggtcca ggtcgaccgc gttttctcgc tcccctcggg gaaacccggc
     7501 ttcgagggcc acgcggccgc cgaacggctc gtgaccagga gcgacaccga gatacgggac
     7561 ggcgagatcc gggtcaccga gtcgacggtc aaggagacgg tccggacggc gtttgccggc
     7621 gtgcccggtg aggtcgtcgt cgccgagagc ggcggcgggg agttcgcgtt cgacctgatc
     7681 ggtgccgaaa ccgacacggc gatagagcgg ggagcgttcg acctcagcgg gttcctcgac
     7741 gcgcaccgga gcggatcacc gtggaaagcc gggttctacg acgcggacgg acacgcacag
     7801 aaggggacgg tctacggtga cgacctcctg cgagacgacg cgttcgagcc ggtgttagat
     7861 accgcgtcgc tcaatcagct gggaatcgat tacgagtacc gaggtcggac ggtgaaggtg
     7921 gacctcaccg agtcggggtt cgtcacggtc caccggccga gcgggatgga caccgcggcc
     7981 tttctcgaat ttctgattgc ggacgtgctt ccccacagta ccggctgagg cgagacggca
     8041 cccgatcgcg ctccgaaccc gaccagccgt acggggacag ttcaggactc gacccgttcc
     8101 gagcgttgca tcgcgtatag ctccgcgtag gtcccgtccc gagccgtcag cgacgagtgc
     8161 gtcccggtct ccgagacccg tccgtcctcg accgtgtata tccggtcggc gttcgccacc
     8221 gtcgagaggc ggtgagcgat tgcgaccacg gtccggtcgc cgtcgagcgt ctcgaccgcc
     8281 cggtggaccc gccgttcgag cgccgtatcg aggtcgctcg tggcctcgtc gaggacgagc
     8341 accggggcgt ccgtcagcaa cgccctggcg agggcgacgc gctggcgctg cccgcccgag
     8401 agcttcacgc cgtcgtcccc gagcacggtg tcgaatcccc gcggtaggtc gtcgaggaac
     8461 tccgtgacga gggcggtctc ggcggcgtcg cggaggtcgc gctccgagac cgaccgcccc
     8521 gcggtgaggt tgtaccggag cgtgtcgtcg aagatgtgcg ggtcctgccg caccatcgcg
     8581 accgtctcgc gccacgcccg caggtcgtac gtctgtatcg actcgccgtt cgccaggatc
     8641 gcgccgtcgt ccggcccgta gaggcgggcc agcagcgaga cgaccgtcga cttccccccg
     8701 ccggaggggc ccacgacgcc gacgaactcg ccgccctcga tctccatcga gagatcgtcg
     8761 aggacccgct cgtcgtcgta ggcgaacgag acgttctcga accgaatctc gtcgatccgc
     8821 tcgggcaccg cagcgcccgc agtctcctcc tggcggtcgg ccagttggtc gatgaaccga
     8881 tgggtccgaa cgaggtgggg aagctccccc tcgatggcgt agacggtggc gttgagcgaa
     8941 ctgagccgcg gcgcgagccg gaacatggcg aacaggaaga cccccagcgc ggacacggag
     9001 agcgcccgat agcggatcgc gacgtagacg agcccgaaca gcgccagcga gacggcgagc
     9061 tggtagaagc tctggatcgc gacctcgttg cgacggaccg cgacgctggt cgtcgcgtag
     9121 cggtcgagcg tggcgcggaa ctccgacaac aggtccgagc gcatcccgaa cagcttcacg
     9181 tcgcggaccc cttgcgttcc ggcctgtgcg gtctcctgga gttgctcgtt cgcggtggcg
     9241 acgcggtccc ccacggcgta gccgggctcg ataccgtatc tgaacaggac ggtgagcccg
     9301 cccagggcca cggcggccgc catcgtcagc aggggcgcga tggccagcgc gatcgcggcg
     9361 taggcgacac agaggagtcc ctgctggaag aactggacga ttcggccgat gacgcggccg
     9421 gcgtaccggg tctgcgtgag gacggcgttg agtacgtcgt cggagccctc ctcgtcgtag
     9481 tacgcgaccg acgcgccgag cgccagttcg taggcccggt ctttgagggc ccgttcgtag
     9541 cccttcgtga gcttcgccgc gagccacttg accgcgaacg cggacgcgta ccgacaggtc
     9601 atcacgcacc cgaggccgag gagcaggaat tcgagcgtga gtggcagccc gacggcggcg
     9661 tagaccgaca ggagccgccc ggcgatcccg ccctcggcgg tcgagagcgc gccgccggtc
     9721 tgtgcggcct cgatgaccgg aaacaggaac gagaggccga tgccctcgag cgccatcgcg
     9781 acgaggctcg tggcgacgat gccactggtc aggagggggc gatgcagcgc cacccggcgg
     9841 agcgatcggt accgctcgcc gcgggggagt tccaactcgg ccatcgtgtt gatcacggcc
     9901 ccttcgagca atagttaccg cctcactacg gtcccctgta cccggttcca cggcggaata
     9961 cggggcataa caatgctgac ccaccgccgt tcccacgggt atggtaacga tagagacagg
    10021 cacgactgtc gtcgcgacgg acgactgcgt cgccacggcg gtcgacgacg aagtgatcgt
    10081 tctcaacagc gagacgggta tgtatcaggg cctcaccggc gtcggaccgg acatctggcg
    10141 actggtgcag gaaccgaccg agttcgacga gatcgtctcg gcgctggtcg cggagtacga
    10201 cgtggacaga gcacgctgtg cgagcgacgt gtccgacttc ctcgagacgc tcgcgacctc
    10261 gcgactcgtc gagaccgatg cgaacgctgc tcggtgaggt cctgtcgcag tccagttcgc
    10321 gccggcggct gctctgtgga accgcgatgc tcatcgtatc gagcaaggtg ctgctggccc
    10381 tcgtcggtct cgaccgttcg gtccgctggg tcgggtatct cgggcgcgtg tccccgccgt
    10441 accgcccggt cgagtcggtg gaacagatcc cgtggtcgat cgacaccgtc gccgcgcgcc
    10501 tcccgggcga gttcgactgc ctcgaccggg cggtggccgg gaacgcactc ctcgcggcca
    10561 gtggctaccg gggtcgaatt cgtctcggcg tcgacaagcg agacgacgcg ttcgaggccc
    10621 acgcctggat cgagtggaac gacgaggtgt tgatcgggga cctcgacgac ctcgatcggt
    10681 tccgaacgct cccggagtcg gaagtagccc cgttttaacg ccgcatcccg ctaagctttc
    10741 gccagtaatt gtcgttataa caaatacagg tacgattgga tactggggtg ggtacaaacc
    10801 catgaactac gaagaaccct ccgtggagac gtacggaacc gttgaagaga agacgaactg
    10861 gtggcacgac gacggctacg gtaagtggga ctgagacgga ctgctgtacc tgtgtactgc
    10921 gacgaccgcg tgactgggtg gggttgagac ggaatcgagg tacggcagtt cggacgtgac
    10981 gggacacctc ccgttccggt atttttcaca cgagatgtct ccgtgagacg gctctggtcg
    11041 ttcgcggcgt gacacgacgc gacttcgaga tggactgtgc cacgcagtgc ccggctcgga
    11101 tgcgttcgac cgccggtata gagcccattc ttaatcgccc catgaccgaa tcgggttcgt
    11161 atgcaccagg ggcgtagcag ccgattccga catcgagaga cggcgaggac cgggtgcgag
    11221 ccgacgctcg cacgcggggg gcggtgagga ccgtggccgt cgcgacgacc gagacgtacg
    11281 aggcgttcgg cctgaccgtc cggtcggaga tcgacctccc cgagctgtcg accgccgacc
    11341 cgggcggtcc cacggacccc gacgtcaccg tcaccgtgcg cacgctgacg cgaccacctg
    11401 ctctcacgtc cgagacgagc ttccacgcgg cgggtcagcg cgactactac ctccagtacg
    11461 acgcggcgac cgtccgcgtt cgggacggga cccgtatcgc cgtcgatccg gcccgtggag
    11521 tcccacacga ggtcctccga cacgtgatcg tcggtccggc gctcaaccac ctgcttcacc
    11581 agcgcggcta cttcgtcctc cacgccagca ccgtctcgat cgacggagcc gcggtggcgt
    11641 tcgtcggcga gtcgggccag ggcaagacga cgaccgcgat ggcctgtctg accgagggac
    11701 accacgtgct gagcgacgac gtggccgcga tcacgctcga cggcggcacc cccgtggtca
    11761 ggagcggcta tcccgcggtg aagctctcta ccgaggccgt cgagacgttc gatccgccgg
    11821 tcgaaccccc ggtacggacc tgcgacgggc ggccgcgaca cttccaccgt ctcagacacg
    11881 accagccggc cagtccagtc ccgttagccg gcgtctacct gctggaagac ggtccggaga
    11941 tcgaagtcga gtcgctctct ggcggcgaac ggatcatgtc gctggtggac aacacgtacg
    12001 cgatcgggac gctcgggtcc gacggacagg ccgccaccaa cgtcggcgtc tgcggtgaaa
    12061 tcgccggtgc gacgtcggtc aagcgcctgc ggcgaccccg agacctcgac cgcctcccgg
    12121 aggtgatcga ccgcgtgcgg gccgatatcg cgggcgagcg atgctgagcg acgccgagcc
    12181 ggaactgcgg ctcgtcatcg aatgcgtgcg cgcggccgtc gaccccggtg cagatcccga
    12241 catcgaaccg ctcgtgtcgt ccgacctcga ctgggaccgc gtcctcgatc tggcccggta
    12301 ccacggcgtc ctccagttgc tccagcaggg gctggcgtcg acgtaccgag aggtcaaaca
    12361 ggagcgcggc gtgcccccgt cggtcagttc gcgcctcgac gggacggtcc agcggcggac
    12421 gatgcggaac ctcgcggcca cggacgaact tcgcggcatc ctcgacgact tcgacgacgc
    12481 caacgtgcgc gcccttccgt tcaagggacc ggtgttgtcc gcgttcgcct acgacagcgt
    12541 gaccgtccgc gagtacaacg acctcgactt cctcgtccac cccgaagacg tgtcgaccgc
    12601 cgccgacgtc ctcgaagaac ggggctacga gtggcgcgac ggcgcgccgc gcctcgacga
    12661 cgcggcgctg ctcggcggat ccgcgacgaa ggcgatcgtc cacgagtacg cgatgactgg
    12721 ctcggacatc gacgtggaac ttcgctggcg cgtcggcgac gcggagcgcc cgttctcgcc
    12781 ggacgtaacg gcgctgtggg accaccgcga gcaggtcgac gtgggcgggg cctcggtgcc
    12841 agcactcgcc ccggaggacc gcctcctcgt actcgcgttc cacgggacga aacaccgctg
    12901 gtacctcctg aagtggctct gtgacttcgt tgctgcgatg gacgcgacga cggccgactg
    12961 ggaccgggtg ctcgcccgtg cacgcgacca cggcgtcgag cgtccgttcc tggtcggtgc
    13021 ggcgctcgcc gggtccgtct tcgagtacgg gcttcccgaa cccgtcgcca cgcgagtgag
    13081 cgaggcgagc ggcgtcactg gcctggccga tcgagtgaga cggtcgctgg cgtccggttc
    13141 gatgtccgcg ccgggccgca tcgagtccgc ccggttcttc gcggccgcga gcgaatcgcc
    13201 gacggcgcta ctccgactcg tcgccctgca ctcggcgctt cacccgacct acgcggacta
    13261 ccggtttcac cctcttccag gccacctgca tccgctctac tacgtcgtct ggccgctcag
    13321 gctactggcc gggttactgc cggaccgaac ggagaccgac cctccgaccg aggaaccgac
    13381 ctgacggccg gcgctcagtc ccgcggctgg atcgttccac cgcccagtcc ctcccaggcg
    13441 actcggtatc cgaggcgcga gagggcggcg ctgtcgtcgg cgatgccgta atcggccagt
    13501 cggtcggcgg ccgtttcgta ggccatcccc gcttcgatgt catcggccag ttcgtccaga
    13561 acgctcgggc gaaccagcgt gcgcccgacg cgctcgtggt cggggaacgc agcgtcggcg
    13621 agcgcgtcct cgctgacgcc gtagtccgcg gcgaggtcgg cgagcgagac gacggccgcg
    13681 tcgggccgca cctcgtcggg gatggcggcg gcgctctcgc tgacgagtcg gtcctcgtag
    13741 gggcgcaggg cgtcgcgcac gtccttcacg cggaccgtcc ctgagtacgg gatggcccga
    13801 ttgtcggtcg cctcgactgc gtcgcccacg ccgagggact cgtcgacggc gacgagcatc
    13861 gccacgtcct caaggtcccc gaggcggtcg agtttcttcg cgacgtactc cggcgtccag
    13921 aaccccatga tctcgaagaa gacgcgaaag ggcgggtcgt cggggccgtc gccggccgct
    13981 cgctcgccgg cgtccctgaa cgtctcccga acgcccccgt ctgttccggg ccgccactcg
    14041 aaggcgaagt cggggatgac gacgtgttcg ccggcggcca gcggctcggg ttcgcggatc
    14101 aggtcccagt ccaggtcgag cgcggcgaac cgcgcggcga agtccgcctc gacgccgctg
    14161 tcgtaactga cctcggtgac ggggtcgacg ccgggtacgg acacgtcggc gtcggaaagc
    14221 gtgagttccc gctccgtccc ccggtcgtcg atcgtcgcca ccaggtccca ctcgtcggcg
    14281 gccgcgacgg tccgcaggag gcgagcgaag cgcgtcccgt accggcgcgt gttcgaaaac
    14341 agcgcgtcgg ggccggtgac gacgacctcg cgaccgcgat cggtccgtcg gatctcgtac
    14401 atgagccgga ggcgcttgac cgccgagacg agcgccttcg ggtcggaaga gcggacccgg
    14461 acctccgtcg cgtcgaacag cgccgtctgg gccagcgaga ggtcgtactg ggtccgaagt
    14521 tcggcgggtc cccaccgcga gtcgacggcg gtgaggacct gcttggactc ccggtcggcg
    14581 tacagcgcgt cggcgagcgt cgacgcgtcc gttccgaagt ggtccgcggc gtcggcgacc
    14641 gcccggtcgc gctcggcctc gctgacgacg ccgacgcgct ccgcggcctc gaacacgcgg
    14701 cggcgcgccc gctcggggtc gaccggggct cgcgtctcga aggtggcctc ccgctcgacg
    14761 agcttggcga agccgcggac cagcttgaag tcgtcggcct cgcgttccag gtccgcgagc
    14821 gcggcctgga ggtccgcgcg cgactcgccc acgtggccct gatacacgcc gaggacgcgg
    14881 gctgcgagtc gctccgcgtc gtcgtcggca aaccggaggt ggtagccgcc gcccgcccgc
    14941 gagacgcgca ggaggtcctt cgtgagcacg ttcgagcgtg cgacgcgcag cgacaaaaac
    15001 gcagggagtc ggcgtgacgg tggcgagagc gccggcgggt cagatcaccg cggtgtcgac
    15061 gcccggtcct cgaacgtgac agtcacggcg acctcgtcct cgatcgaccg accgatggct
    15121 cgctcgaggt cgccgacgag tcccggatat ccgcgttcgg ccggccgact gaccgcgact
    15181 gacacctccc gatccagtcg gtagaccgtg acgccgccga agcgggtctg caccgagagc
    15241 agtcggagtt ccgcataggc gtcgtccgac agcgtctcgg tgacggcggc gttgacggcg
    15301 gtctcgacct gcatctgctg ggcggtgacc gtccccgcgc cggcgaacgc gaccaggagc
    15361 aatagcacgg cgatggccgt cggcgcgtgg gcgcgaacgg cctcggccgg agacgcgtct
    15421 gcctcccagt cgagcgggcg gaaccccagc caccagagca ccaggaaccc ggtgagattg
    15481 atcgacgtga cgttgacgac cagcaggata cccgcaccga gcgcgacggc gggcaggccc
    15541 caggcgatgc cgacgccgac cgcggcggcg gcggggatca gcgcggcggc gatcatcacg
    15601 ccgaccagcg agacggggag cgccgtcgcc aggccgaagg caccggcggc accggcacag
    15661 agaccgacgg ccatcgagag aaagcccggg gagattcgct gggcgatctg ctggaccgtc
    15721 gtgacccgga ggcgcgcggg gacgaacccg ctgtatcgga tgaacaggcc gaacaccgcc
    15781 gcgctcgcga ccgcgacgac gaggccgagc aactggtcgc gaaccccctc gacgatgagc
    15841 tcgcggtcgc tgagcgccgt cccgacgctg gcgatgagcg ccgaccccac ctgtggggcg
    15901 atgaccatcg acccgacgac gacggccggc gagtcgagca acagccccgc cgtggcgacg
    15961 atggcgctca ggatcgtcat gccgtagtag gtcgccttcc cgggattcat tccccgagcc
    16021 cgaccgcgga gttcgtcgtg cgagatgcgg tcgtcgtagt tccgagcgga gttcgactgg
    16081 tccggtctgg cggtctcggc cgtgccgacg accgcgtacc gatcggtgtc gagacccgcc
    16141 gcctccatct ctgcgagcac ctcgtcgatc gcctccggcg ggagcggaaa ctggagcagg
    16201 aacgcagtct cgtcggcgct ctcctcgacc gtccgaacga agctgatgtc gcggtcgtcg
    16261 aggacggccc ggacgtcgtc cagttcgtcc tcggtgactc gaatgtgtat cagccgcact
    16321 actcgctcct cccccaccgc cgctcgcgaa gtcgtgcgcc gagcatctac ccggccatca
    16381 tgggtttcac gcttacttat acaggtagta acccaggcga ccgcacaagg cgacggtccg
    16441 gcggcgcgct atcgccgccg cctggcgacc cgttcctcgg ccgtctcctc ggtgacgagt
    16501 tcgtacagca gggcccgcga gccgtcgtct ttcggacgca ggatgcgacc gagccgctgc
    16561 gtgaactcgc gctcggagcc gctgcccgag aggacgacgg ccacgttcgc gtcgggcacg
    16621 tcgaccccct cgtcgaggac gttcgccgtc acgacccgcg agtaggaccc gtcgcggaac
    16681 cgctccagta tctcgcggcg ctcgctcgcg ccggtctcgt gggtgatcgc cgggaccagg
    16741 aatcgctcag agagccggta gacgaggtcc gtgaaggcgg tgaatacgat gactcggtcc
    16801 ccgcggtggc ggtccaggat ctccgccagt cggtcgacct tccgctcggc gttcatcatc
    16861 acctcgcggg cgcgctgttt cgccagcagg gcctcgcgcg ccgccggatc cgtccccgag
    16921 cgcttgacca gttcctggta gtcgctccca gagcggagct ggatgttcga gcgctgcagg
    16981 tagtccgtga acgttccctg ttcgtcctcg tatcgctcgc gctcttcggg ggtgagcgat
    17041 acctcgatgc gcttgatgtc gtagtccgcg aggtgctcgc ccgcgagatc gtcgaccccg
    17101 acccgctgga cgagcggccc gacgaggccc tcgatgacgt cgtgcgcgcc gtccggccgc
    17161 tcgaacgtcg ccgtgagccc cagtcgggcc ggagccgcga gcaggcgggc gatgtcgcgg
    17221 tacccctcgc cgccgaggtg gtggacctcg tcgaagacga cgagcccgaa acggtcgccg
    17281 agctcgtcgg cgcggaggta cgccgagtcg taggtggaga cggtcacgtc ctcgacgcgc
    17341 tgctcgcccc cgcccatgcg accgacgggc cggtcgaact cccgttcgag ttcccgctgc
    17401 cactgttcca gcaggtcgat cgtcgggacg accaccaagg tgggcgtccc gagcgcgacc
    17461 atcgcggcga tgccgatgac ggtcttcccg ctccccgtcg gcagttccag acagccccgg
    17521 tcgccggcgg cgcgccacgc gtccagcgcc gattgctgat actcccggag gtcgtacgtc
    17581 gtcgaaagcg ataccggagg cagcgggccg acgcggtccg cgtacgcgac gccgcgctcg
    17641 tcgagcgcgg tcaccaggtc ggcgtaccgg tacgccggcg ctctggcgga ttggctccgc
    17701 tcgtcgcgct cgaccccggg caggtcggtc ggcggcgacc cgctcacgcg aatcgtcccc
    17761 gactcgaacg tcagttccag cacggccgac ggttcgccgc tcccgccgat aacgctttcg
    17821 cggcggctgc cgaccgggca cgcgtccgcc gcggagccct ccgggcaccg tcgtttcgca
    17881 ctgactccgg gagcacagtt tacgtccgtc cagaccgaac agtcccccat gacaccgact
    17941 cgctcgacgc tgctcgccct cctggtgtcg ctgtcgctcg tgcttgcgac cgtgccggcc
    18001 ggtgtgacgg cgatacagat gaccgacaca cagacggcca cggacacgct gaccgtcgat
    18061 cgcgacggct ccgccgacta ccggtcgatc caggctgccg tcgacgccgc cgacagcggc
    18121 gacaccgtcg cagtccgacc cggcgtgtac tacgaacaga tcaccgtggc cgagaacgtc
    18181 acgctggtcg cacccgaccg ggcgatactc gacggctcgc ggttcgtcaa cggcaccgcg
    18241 ctgcgcgtga ccggcgcggc cgccccgaac gtcaccggct ttacgatgcg taactaccgc
    18301 ctcggcgtcg tcgcgaacga caccaccggc gactggacgc ttcgtgactc gaccgtcatc
    18361 cgcgccagcg tcggcgtcta cgcgcccaac gccagcggga actggacgat cgcggactcg
    18421 gccgtctcca gcacgaccta cagcggcgtc ttcgcccgcg cgacgaccgg cgagtggacg
    18481 atccgcgaca cccgcttcgt cgaagtcggc ggcgacggcg tcgacgtccg ccgctcgacg
    18541 ggcgactgga cggtatcgga catcgtcgtc gaccgctccg gcgcggacgg cgtcgacgcg
    18601 tccgggacca ccggcgactg gaccgtacgg aacacgacgg tccgccgcag cgacaccggc
    18661 gtcaaagcca tcgccagccg cggcgattgg accgtgaccg acctgaccgt ccagcgcagc
    18721 gacaccggcc tcgtcacggc gtcgacgagc ggcgattgga cggtttctga tgccactgtt
    18781 accactcgcg agatcggcgt cttcaccgcc cgaaccaccg gcgcgtggac gattcggaac
    18841 agcaccatcg atagtcggtt ccaagggatt cacgccgccg ggacgaacgg gtcctggacc
    18901 gtcagcgact cgtcgatcac cgtctccggg aatgcggacg cgatcggcgt cgacgcccgc
    18961 gacgccgccg agggctggtc gctcgattct gtcgacattc agagcaccgg cgtcgacgtt
    19021 gccgagtgac cgcaggacgc gactccaaac ggtccggcgc cgtcgtccgg aaaacgaagc
    19081 ccttaattaa agcacccccc tctccccgag tgcgggaccg tggggtagcg gtatcctcgg
    19141 cgcatggggt gcgtcggacc tgagttcgaa tctcggcggt cccacttcaa cttctaccag
    19201 atgccgacac ctgtacgctt aggtaaccga gggtccaaat tccttcgtct atcccctaga
    19261 atttagtcgc tctttaaata cctctgagag acgaccggtc acccaccgac gcgctgtccg
    19321 agactacttt cactttcact ccggacatgg ctgatgtcct ttatcctgca aacaggaacg
    19381 gctcacatga acagcaccgg cgatgccgat cgggtcggac agagatgcct gggggacggg
    19441 catgagtaga tccgtcagcg agaaactcgg cgaagggtgg cggatgatgt gccctgagaa
    19501 ccatcacaca ttggaggatc aggtcggacc gacggtctac tgtgaacagt gtaactgcgc
    19561 ctatcggtac gacgacctca tcgacaaggc ggaactgggc agtggaaagc ggggctatcg
    19621 acactagtgt ccagctcaca gacctcgcaa aagagatggt agcgattcag gcaccgcatt
    19681 cgtcttcgag tcccaccctg tgcctgatgt ggacgcaaac ggtcggccgg ggacaccgag
    19741 aaccaccggt cgggaccagc gccgtcgcgc cggcgacgca gttaccgtcc gttcgggaac
    19801 agtctagaca ggagtccgcc gcgtgacgag ggatcgaagt ggcagtaggc gaggaggagc
    19861 accgcgcggt ccgtgagcgc gacgcgtttg gtctgttcgt cgtattcgac gacgccggcg
    19921 tcggccagtt tcgggaggtg cgtctggtgt aaggagacgt agacgttctt gcgctggctc
    19981 gcggagacgt cggcgccgcc gtactcggac tgggcgaggt ggtcggtgat cgctgggacg
    20041 gccgattcac cgccgacgga ctcgacgaac cggaggagat cgcgccggcg gcggttggag
    20101 aggagcgaaa agatctggtc ctcggtgagt cggttcgtct cgctcgcctc tgctcgtcga
    20161 ttactggcca ttcgggacac cggatacgat gggtaaggtc tctgtcggat atatccgttc
    20221 gtaccacatt gccgtgggta cgagcgagtt acaccatcgg agtgagagcc gtcggtgcgg
    20281 ctacggatga cgaatcg
//
