LOCUS       NZ_NKBC01000025        21890 bp    DNA     linear   CON 17-MAR-2024
DEFINITION  Bacillus paralicheniformis strain 9-1 9-1_R1_(paired)_contig_25,
            whole genome shotgun sequence.
ACCESSION   NZ_NKBC01000025
VERSION     NZ_NKBC01000025.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus paralicheniformis
  ORGANISM  Bacillus paralicheniformis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 303950)
  AUTHORS   Cui,Y.
  TITLE     Improper usage of probiotics constitutes a potential risk of public
            health
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 303950)
  AUTHORS   Cui,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JUN-2017) Beijing Advanced Innovation Center for Food
            Nutrition and Human Health, College of Veterinary Medicine, China
            Agricultural University, Yuanmingyuan West Road, Beijing 100193,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 9.5.3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 20x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009935535.1-RS_2024_03_17
            Annotation Date                   :: 03/17/2024 02:24:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,539
            CDSs (total)                      :: 4,461
            Genes (coding)                    :: 4,361
            CDSs (with protein)               :: 4,361
            Genes (RNA)                       :: 78
            rRNAs                             :: 4, 1 (5S, 16S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 68
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 100
            CDSs (without protein)            :: 100
            Pseudo Genes (ambiguous residues) :: 0 of 100
            Pseudo Genes (frameshifted)       :: 49 of 100
            Pseudo Genes (incomplete)         :: 64 of 100
            Pseudo Genes (internal stop)      :: 15 of 100
            Pseudo Genes (multiple problems)  :: 21 of 100
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:47:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 259628
            Orig. end                         :: 281518
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            NKBC01000025.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21890
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21890
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21890
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11890](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11890)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    939..955
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 23.21"
                     /tool="antismash"
     gene            1098..3932
                     /gene="sucA"
                     /locus_tag="CE036_RS21895"
     CDS             1098..3932
                     /EC_number="1.2.4.2"
                     /GO_component="GO:0045252 - oxoglutarate dehydrogenase
                     complex [Evidence IEA]"
                     /GO_function="GO:0004591 - oxoglutarate dehydrogenase
                     (succinyl-transferring) activity [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /GO_process="GO:0006554 - lysine catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006568 - tryptophan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sucA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389819.3"
                     /locus_tag="CE036_RS21895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="2-oxoglutarate dehydrogenase E1 component"
                     /protein_id="WP_020451820.1"
                     /transl_table=11
                     /translation="MFQNSMKQRMTWEEFHGPNLGYVLELYDQYVKDPESLDADLKEMF
                     DELGAPPGDIRAASLKNEEADFTAGSIQKIASVIKLAEDIRTYGHLNASVNPLRKTQEK
                     QELFPLAEYGLTEQDVKKIPASVICKDAPKEVTNGLEAIQYLKNTYKKSISFEFDHVHI
                     FEERNWLMKKIESGELFAPKSKEKLVEVLRRLTEVESLEQFLHKTFVGQKRFSIEGLDA
                     LVPMLDDIIAKSVSAGTTNVNIGMAHRGRLNVLAHVLGKPYEIIFSEFQHAPNKDLVPS
                     EGSTGINYGWTGDVKYHLGANRQIQDEHTKTARIALANNPSHLEFIDPIVEGSTRAAQE
                     TRTESGYPLQDVKKSLAILIHGDAAFPGEGIVAETLNLSQLKGYQVGGAIHIIANNMIG
                     FTTESNESRSTKYASDLAKGFEIPIVHVNADDPEACLSAVQLAVEYRMTFNKDFLIDLI
                     GYRRFGHNEMDEPSATQPMLYDAVRKHPTVKNIFAEKLIHNGIVDNETVDKIGDAVMKR
                     LEEAYRKVPAKKEDMTHEIVLPEPVSNGFPDVDTSVDVETLRKINQELVSWPENFNVFD
                     KLKRILERRAKAFDDDRKVDWSLAEAMAFASILKDGTPLRLTGQDSERGTFAHRNLVLH
                     DSKTGDEFIALHHLADTKASFAVHNSPLSEGSVLGFEYGYNVSSPETMVIWEAQFGDFA
                     NAAQVYFDQFISAGRAKWGQKSGLVVLLPHGYEGQGPEHSSGRTERFLQLAAENNWTVA
                     NLTSAAQYFHILRRQAKMLLREEIRPLIIMTPKSLLRNPNTVSEVQELSDSNFKPVYEM
                     SGLSHQYDKVTRLVLSSGKVSIDISSHFNKMEGEKDWLHIARVEELYPFPAKHIKAIFS
                     KLPNLEEIVWVQEEPQNMGAWNYIEPYLREIAPKDVKVRYIGRRRRSSPAEGDPTVHKK
                     EQERIVSDSLTRKN"
     gene            3947..5227
                     /gene="odhB"
                     /locus_tag="CE036_RS21900"
     CDS             3947..5227
                     /EC_number="2.3.1.61"
                     /GO_component="GO:0045252 - oxoglutarate dehydrogenase
                     complex [Evidence IEA]"
                     /GO_function="GO:0004149 - dihydrolipoyllysine-residue
                     succinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="odhB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389818.2"
                     /locus_tag="CE036_RS21900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="2-oxoglutarate dehydrogenase complex
                     dihydrolipoyllysine-residue succinyltransferase"
                     /protein_id="WP_023857354.1"
                     /transl_table=11
                     /translation="MAEIKVPELAESISEGTIAQWLKQPGDYVEQGEFLLELETDKVNV
                     ELTAEQSGVLQEVLKDSGDTVQVGEIIGTISEGEGEGGQSTAPQADAQESAGATEEKPA
                     TSEKTAEPRESANDEADTTKTRTIASPAARKLAREKGIDLSEIPTGDPLGRVRKQDVES
                     YQKNEQPPKAQPEPKRETQAPAAKQTENAGKPVERQRMSRRRQTIAKRLVEVQHTAAML
                     TTFNEVDMTAVMNLRKRRKDQFLEQHDVKLGFMSFFTKAVVAALKKFPLLNAEIQGDEL
                     VIKQFYDIGIAVAAPDGLVVPVVRDADRKTFADIEKDIGELAKKARNNKLSLNELQGGS
                     FTITNGGTFGSLLSTPILNSPQVGILGMHKIQLRPVAIDEERFENRPMMYIALSYDHRI
                     VDGKEAVGFLVTIKNLLEDPEQLLLEG"
     gene            complement(5259..6239)
                     /locus_tag="CE036_RS21905"
     CDS             complement(5259..6239)
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003182690.1"
                     /locus_tag="CE036_RS21905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bile acid:sodium symporter family protein"
                     /protein_id="WP_023857353.1"
                     /transl_table=11
                     /translation="MSYLIKISQFAGKTFAIWVILFAVLGFAFPTQFTWITPYITILLG
                     VIMFGMGLTLSADDFKELLRRPLHVLIGVLVQYTVMPLLAFGLAYGLGLPSEIAVGVIL
                     VGCCPGGTASNVMTFLAKGNIALSVAITTVSTLLAPFLTPFLILFFAKEWLPVSPGSLF
                     LSILQAVLLPIIAGLIVQFFFTKQVKKAVQVLPLVSVLGIVAIVTAVVGGNRENIIQSG
                     LLIFAVVVLHNGLGLFLGFVLAKCFKMDYASQKAVSIEVGMQNSGLGAALATAHFSPLS
                     AVPSAVFSVWHNLSGSWLATYWSKKANKQKNNNYSPAPQMINKKL"
     misc_feature    complement(6291..6305)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.26"
                     /tool="antismash"
     gene            6454..7794
                     /locus_tag="CE036_RS21910"
     CDS             6454..7794
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003182687.1"
                     /locus_tag="CE036_RS21910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sodium-dependent transporter"
                     /protein_id="WP_020451817.1"
                     /transl_table=11
                     /translation="MENQQNIWSSKLGFILASAGSAIGLGAIWKFPYVAGTSGGGAFLL
                     MFILFTLLIGLPLLMAEFIIGRKTQKDAVESYKELAPGSLWHWIGRLGIITCFILLSFY
                     SVVGGWIIIYIIKGLTGELSRSTDYAGLFGETIANPYLVLASQFAFIMITILVVAKGVR
                     SGIEKASKFMMPALFVIFLLLIIRSLTLPGSMEGLEFFLKPDLSHITAKTVLFALGQSF
                     FSLSVGVSVMVTYSSYLSKKENLIQSAVSVTLLNVSVAILAGFAIFPAVFSFGLSPDAG
                     PMLLFNVLPSVFHKMPLGIVFLLAFLLLFLFATLTSAFSMLEILVSSLSKGDPKKRQAF
                     AWAGGIAIFLFGIPSALSYGVLQDVSIFNLSIFDAADYLVSNILMPLGALLIAVFVPLK
                     IPKEELFAELREGSKISRKWFAAWLLLIRYAAPIVIIVVFLDVIGVF"
     gene            complement(8019..8432)
                     /locus_tag="CE036_RS21915"
     CDS             complement(8019..8432)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003218040.1"
                     /locus_tag="CE036_RS21915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="stress response protein YvgO"
                     /protein_id="WP_234025611.1"
                     /transl_table=11
                     /translation="MSIPTSLNQSLDQEKQQFKTSAINLNINLDLLGIGNSIRDAIVQS
                     SNRSGFVKNCMETAFYSAGQRYNVMVFNLSQGYQNGLRGVKFYGSANYHGVIYGIWVFE
                     SGQFTNQGDGGWINWAFKGWFDRNGQTVTFRMP"
     misc_feature    complement(8918..8934)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 24.42"
                     /tool="antismash"
     misc_feature    8918..8934
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 24.82"
                     /tool="antismash"
     gene            complement(9165..9950)
                     /locus_tag="CE036_RS21920"
     CDS             complement(9165..9950)
                     /EC_number="1.15.1.1"
                     /GO_function="GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006636256.1"
                     /locus_tag="CE036_RS21920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="superoxide dismutase"
                     /protein_id="WP_223254869.1"
                     /transl_table=11
                     /translation="MKDDPSIVSQLEKLFQSLDDPRATEQEWYEQAEAVYQAISRSDAS
                     QAGRQPFRTVPIGGHRLPSLPYSYSALEPYISREIMFLHHTKHHQSYVDGLNKAEKELQ
                     KARQTKQFDLVNHWERELAFHGAGHYLHTIFWYAMHPKGKRRPTGELLEMINRSFGSYS
                     AFKEQFSEAAKKVEGVGWAILVWAPRSHRLEILIAEKHQLMSQWDVIPLLPLDVWEHAY
                     YLQYKNERAKYVDNWWNVVDWREPERRFATAKRVLWEPF"
     misc_feature    9905..9916
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.78"
                     /tool="antismash"
     gene            complement(10001..11890)
                     /locus_tag="CE036_RS21925"
     CDS             complement(10001..11890)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003182681.1"
                     /locus_tag="CE036_RS21925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_079289256.1"
                     /sec_met_domain="T2TS (E-value: 1.3e-108, bitscore: 358.1,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSLLEDVKAFRQKTLAKLQNRQRPDGSWRFCFEGPVMTDSFFIL
                     MLTSLGDQDSSLITSLAERIRSKQSGDGAFRNHPDETAGNLTATVQGYTGMLASGLYDR
                     RDAHMQKAEAFIKATGGLKNVHFMTKWMLAANGLYPWPRAYIPLSFLLIPPYFPLHFYH
                     FSTYARIHFVPMAITFNRRFSLKNNQIGSLRHLDEAMSKNPLEWLNIRSFDERTFYSFN
                     LQWKQLFQWPAYVHQLGFEAGKKYMLDRIEEDGTLYSYASATMFMIYSLLAMGISKNAP
                     VVKKAVGGIKSLISSCGEEGFHLENSTSTVWDTALISFAMQESGIPEQHSSISSAADYL
                     LKRQHVKKADWAVSNPQAAPGGWGFSHINTNNPDLDDTAAALKAIPFQRRPAAWNRGLT
                     WLISMQNKDGGFSAFEKNVDHPLIRNLPLESAADAAVDPSTADLTGRILHLLGLKERLT
                     DDHPAVRRALRWLDHHQEADGSWYGRWGVCFIYGTWAALTGMKAVGISHNHASVRKAVS
                     WLKSIQLEDGSWGESCKSCEAKRFVPLHFGTVVQSSWALEALLQYERPDDPKILKGIRF
                     LTADHESSPERLEYPTGIGLPKQFYIRYHSYPFVFSLLASSAFIKKAEMRETY"
     gene            12123..12524
                     /locus_tag="CE036_RS21930"
     CDS             12123..12524
                     /EC_number="3.5.4.5"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003182679.1"
                     /locus_tag="CE036_RS21930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytidine deaminase"
                     /protein_id="WP_035338563.1"
                     /transl_table=11
                     /translation="MNIEQMLYDTAVELIKKRYPTGWGGAAAMYTEDGRILTSVAPEVI
                     NASTDLCIETGAILEAHKYQAKITHSVCVVRDDEHSECKVLTPCGVCQERLFYWGPDLK
                     AAVTVPDGRLLYKSLKEIQPYHWFAAYQK"
     gene            12542..13078
                     /locus_tag="CE036_RS21935"
     CDS             12542..13078
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003182677.1"
                     /locus_tag="CE036_RS21935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family protein"
                     /protein_id="WP_079289255.1"
                     /transl_table=11
                     /translation="MFECRKVYLRPVEKGDMESFYKAVQNEDIRYMTGTTREFTMEDLY
                     EHYERITSDETRYDFAVCLKEDDRLIGDLSIIDIDRTNRKAGFRIALHSPAYLNKGYGS
                     EAVRLAMQFAFERLDLNRLQLEVFSHNKRALKAYEKAGFKREGTVREALYMNKQYSDEI
                     IMGILKREYEELISR"
     gene            complement(13207..14343)
                     /locus_tag="CE036_RS21940"
     CDS             complement(13207..14343)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="CE036_RS21940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_223254866.1"
                     /transl_table=11
                     /translation="MTIIVMVDVFKETNSVFGSGLVLALSSFGSVLGGAMASFAIQRLD
                     LLQTAACSTWFRAVCALCIGLCQSLGLPSYIIYVLLFLQSFVGSWYSPAQLGLLYQAIK
                     KRDYVAASGSIVTVNQFVQAAGWGLGGYLTVLAQTHTLTLFTAGLFFVSGLLIKLPDLK
                     TAVIPRQKTRTQSVWRTVYRKKTVLLLTMMDMSEGLANAVWTSAVLLAFTKEVLNKGEA
                     WWGFINAGYFLGAILGGILAVLFSNQLKKRLGLMIVLGSVSMGITTLLFAYSSNPLLSV
                     ILCIMMGPLYQVRDVSQTVILQDTLTDEERAPVTAAKNTILTAWSVLTIAIMGALADLI
                     GVQSVFIAAAVLYAGTAAVTFFVRDVRTYSQSARQIER"
     gene            complement(14565..16052)
                     /locus_tag="CE036_RS21945"
     CDS             complement(14565..16052)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389813.1"
                     /locus_tag="CE036_RS21945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_035339375.1"
                     /sec_met_domain="Aldedh (E-value: 6.8e-196, bitscore:
                     645.5, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSLTMQVSKKLEVFLQGTKKLYINGEFVASASNKTFETPNPATG
                     ETLATLYEAGPEDVDKAVKAAREAFDRGEWRTMNPAERSRLMYKLADLMEEHKTELAQL
                     ETLDNGKPISETTAGDIPLSIEHMRYYAGWATKITGQTIPVNGPYFNYTRHEPVGVVGQ
                     IIPWNFPLLMAMWKMGAALAAGCTVVLKPAEQTPLSALYLAELIDEAGFPKGVINIIPG
                     FGETAGEALTDHALVDKLAFTGSTEIGKKIMEKAAKSVKRVTLELGGKSPNIILPDADL
                     KKAIPGALTGVMFNQGQVCCAGSRVFIHKDQYDKVVDEMAAYSKSLRQGAGLHEDTQMG
                     PLVSKEQHERVLSYIEKGRQEGAKIAAGGTCPYEQGYFVSPTVFTNVEDEMTIAKEEIF
                     GPVLAAIPYETVDEVIERANRSEYGLAAGVWTENLKNAHYIADRLQAGTVWVNCYNAFD
                     AASPFGGYKQSGLGREMGSYALDNYTEVKSVWIHTGE"
     gene            16320..16529
                     /locus_tag="CE036_RS21950"
     CDS             16320..16529
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003182671.1"
                     /locus_tag="CE036_RS21950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6501 family protein"
                     /protein_id="WP_020451809.1"
                     /transl_table=11
                     /translation="MIHEKWQNNNTIKKVKCIHTDAKKYIVNRALTVGNVYEVKNETEE
                     FLFIIDNTNKVGGYYKEYFEEVKA"
     gene            16966..17310
                     /locus_tag="CE036_RS21955"
     CDS             16966..17310
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010331300.1"
                     /locus_tag="CE036_RS21955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PH domain-containing protein"
                     /protein_id="WP_020451808.1"
                     /transl_table=11
                     /translation="MGVFSASKTADGKKFEPLLIEGEKIESVCRLRIDQICFTNKRIIF
                     FDNKLFSKKKVRVFLPYRSIEGFAIREVSMFNPDSSLSLMTSSKIFDLEFTKDTDMLEI
                     QALLSKYLCA"
     gene            17423..17911
                     /locus_tag="CE036_RS21960"
     CDS             17423..17911
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017417961.1"
                     /locus_tag="CE036_RS21960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="WP_020451807.1"
                     /transl_table=11
                     /translation="MPLTQKQKDHLYHKLIDLKQSLSPAEGTDQSMAEETGELSNGVDN
                     HQADHASVYFERMREQTFRQTDRNLLKEVEDALKRLEDGTYGICEATGQEIPYERLEAV
                     PYARKTAETQAETEKRNQEGEGYDEQFTRQMKDLTNRETMDQKRSYAYERLDEEQDSK"
     gene            17941..18345
                     /locus_tag="CE036_RS22855"
     CDS             17941..18345
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012382.4"
                     /locus_tag="CE036_RS22855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_237612078.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 3.1e-09, bitscore:
                     30.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALFVKRDVLQLSTGSQVLDTIKHLSVIGGLIAAIDILEKNPDIQ
                     EKLHENEKYLRDGIQQIGLNVLHSESPIIPIILPDRDTTLRFADSLHQEGVYVNPILLF
                     AYLFLKLLRRAHEILPLCVLVDMFLAFGSW"
     gene            complement(18233..18637)
                     /locus_tag="CE036_RS22640"
     CDS             complement(18233..18637)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CE036_RS22640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_198941261.1"
                     /transl_table=11
                     /translation="MKKNDIQKATFQRYLEASGIIRKLFGNIQLKDMNDIAVQRKIDEY
                     AKKRSHSTTRSLLIKVKMALRDAYARGYLTNDFAELVKPRGKELSKRNKALSITNFQKL
                     RTYLLAHTEEEFHVLVLVALETGMRRGELG"
     misc_feature    complement(19376..19389)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.22"
                     /tool="antismash"
     misc_feature    complement(19377..19390)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.11"
                     /tool="antismash"
     misc_feature    19378..19391
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.0"
                     /tool="antismash"
     misc_feature    complement(19379..19392)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.52"
                     /tool="antismash"
     misc_feature    complement(19384..19393)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     gene            20064..21527
                     /locus_tag="CE036_RS21970"
     CDS             20064..21527
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019423287.1"
                     /locus_tag="CE036_RS21970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="serine hydrolase"
                     /protein_id="WP_025811298.1"
                     /transl_table=11
                     /translation="MGSKMIIITIITVFMLFVGFNTSAYALTEEESVAIQSLLEDARRI
                     SGTPGMSVSIQSRDDTYFFSSGYANSEEGILTNENTIWELASVSKAFTALGILLLEEQG
                     FLSMDDSVVEYLPWFSLRYQGQPVDMQSVTLNHFLHHTTGLINRYHTQHIPEGNTPDML
                     QKTVEMLIDAEVVFPPGERYEYGTVNYDVLGLVIETVSGQSFEDFMEEQVFRPLGLYET
                     YANRGKVQATGQLAQGYRSAFFMTLPYDAPEFRGNTPAGYLFSSSQDIARWMGIQLGIV
                     EDIPEIFQGLIAKSHEGNRSVAAVDELYYGAGWVVNADQTFIQHAGGNPTFATNIFLFP
                     EEQLGISLLSNSASTNIDMLYNIKDILDGNISQSYQMSLMQISDIALSSATIALTLLAI
                     LFFFLGVRRKKQNRKLPLTKKRLILIAFWLVTTIFIGILCLILPTIFGASWRSFLVWQT
                     YSYLTALIALSLLSASITWFVYCYRYKCS"
     misc_feature    21534..21546
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 20.05"
                     /tool="antismash"
     misc_feature    21678..21691
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 20.06"
                     /tool="antismash"
ORIGIN
        1 aaaaaacgct cccgagaacc gatttgcatg caggtagatt gaacaataaa ctgctccgtt
       61 actttacaga gcgcaatccg cgcctcttct ataaaaagca agaaccgtca acagagatcg
      121 acgccgtttt tacattgctc gtcgactgtt cagcaagcat gcatgacaaa atggccgaga
      181 cgaaacgggg cattgtcctg tttcacgaag cgcttaaatc tgttgctgtc cctcaccaaa
      241 tcgtcggttt ttgggaagat acgaacgatg cgacagagac gagtcagccc aattactttc
      301 atacggtcgt ctcttttgcg gattccttaa aagcaggcgc cggaccgcat gtcatgcagc
      361 ttgaaccgga ggaagacaac cgggatggat atgcgatcag acagatgacg aagatgcttg
      421 ttcaaagaag cgaagctcag aagttcctga ttgtcttttc agatggggag ccagccgcat
      481 tcgattatga acaaaacggg attgtcgata cacatgaagc cgttatggaa gcgcggaaac
      541 gaaatatcga agtcatcaat gtatttttat caaacagcga aatcgaagaa tcgcaaatca
      601 agacgataca ggacatgtac ggaaagtaca gccttttcgt cccggacgtc gatcagcttc
      661 ccgatgttct gtacccgctt ttaaaaaagc tgttgaacaa aagtataggc tagataggac
      721 agatggcagc aatactcgcg gccatctgtt ttttatcgta gaaacacagt gaaatattga
      781 aatttttatt atttttatca acttaatttt ttgcggagca catcgggatg ttaaaaaata
      841 gacggtcagg ggaaatatgt gaataaataa tgagccggtt taaaagaatt cggtctgaaa
      901 gttcaaaatt ataaaatttt ttatttttca agatgatttt ttaattttat ttgaacaatc
      961 tgtgtagaaa caaatgagaa acagtggtaa aatgtacgtg gaagcgtttt tattacatat
     1021 ttctgggcgt aaggttcaga agatatatta agatagtgaa tcattcactt gattattagg
     1081 ttgggggtaa tgttcaaatg tttcaaaata gtatgaaaca aagaatgact tgggaagaat
     1141 ttcacggtcc gaacctcggc tatgtgctgg agctttacga tcaatacgtc aaggatccag
     1201 aaagcttgga tgctgattta aaagagatgt ttgacgaact tggagctccc ccgggcgata
     1261 taagggccgc ctctctaaaa aacgaagagg cagatttcac ggctggatct attcaaaaaa
     1321 tcgcatcagt gataaaactc gcagaagata ttagaaccta tggccattta aacgcttccg
     1381 tcaatccact gagaaaaaca caagagaaac aggagctttt tcctcttgct gagtacgggt
     1441 taactgagca ggatgtgaaa aaaattccgg cgtctgtcat atgcaaagat gcccctaaag
     1501 aagtaacgaa cggtttagaa gccatccagt acttgaaaaa cacatacaaa aaatcgattt
     1561 cttttgaatt tgaccatgtg cacatttttg aagagcgcaa ctggctgatg aaaaagatcg
     1621 aatccgggga attattcgcc ccgaaatcga aagaaaagct ggtggaagtt ttaagaaggc
     1681 tgacagaagt tgaaagcctt gaacagtttc tccacaaaac ctttgtcggg caaaaacgct
     1741 tttcaataga aggacttgat gcgcttgtgc ccatgctgga tgatattatc gccaagtccg
     1801 tttcggcagg tacgacaaac gttaatatcg gaatggcgca caggggccgc ctgaacgttc
     1861 ttgcgcatgt gctcggaaaa ccttatgaaa tcattttttc tgaattccag catgcgccga
     1921 acaaagatct cgttccgtcg gaaggttcga cagggatcaa ttacggctgg acgggtgacg
     1981 taaaatatca cctcggcgcc aaccgtcaga ttcaggatga gcatacgaaa acggcgcgca
     2041 ttgcgctcgc gaacaatccg agccacctgg agttcatcga tccgatcgtt gagggatcga
     2101 caagagccgc ccaggaaacg agaacggaga gcggctatcc gcttcaagac gttaaaaaat
     2161 cgctggcgat tctgattcac ggcgatgcgg cattcccagg ggaaggcatt gtcgcggaaa
     2221 cgctgaattt aagccagctt aaaggctatc aggtgggcgg agcgattcac attatcgcca
     2281 ataacatgat tggctttacg acggaaagca atgagtcaag atcaacgaaa tatgcaagcg
     2341 accttgcaaa aggttttgag attccgatcg tccacgtcaa tgcggatgat cctgaagcat
     2401 gcctttcagc ggttcagctc gctgttgaat accgcatgac tttcaacaaa gactttttga
     2461 tcgatctgat cggctaccgc cgtttcggcc acaatgaaat ggatgagccg tctgcaacgc
     2521 agccgatgct gtatgatgcg gtcagaaagc acccgaccgt caagaacatc tttgctgaaa
     2581 agctgattca taacgggatc gtcgataatg aaaccgtcga caaaatcggg gacgctgtca
     2641 tgaagcgttt agaagaagcg tatcgcaaag tgccggccaa aaaggaagat atgacgcatg
     2701 aaatcgttct tccggaacct gtttccaacg gttttcctga tgttgacacg tcggttgatg
     2761 ttgaaacttt gcgcaaaatt aatcaggagc ttgtttcatg gcctgaaaac ttcaacgttt
     2821 tcgataagct aaagcgaatc ctcgaaaggc gcgccaaagc gttcgacgat gaccgaaaag
     2881 tcgactggtc gcttgcagag gcgatggctt ttgcatccat tttgaaagac ggcacacctc
     2941 taaggctgac cgggcaggat tcagaacgcg gcacattcgc acaccgcaac cttgtccttc
     3001 acgacagcaa gacaggggac gaattcatcg cactgcatca ccttgcagat acgaaagcgt
     3061 catttgcggt tcacaacagc ccgctttctg aaggatccgt ccttggcttt gaatatggat
     3121 ataacgtgtc ttcgccggaa acgatggtga tctgggaagc gcagtttgga gactttgcaa
     3181 acgcggcgca agtgtacttt gatcagttca tttctgcagg aagagcgaaa tggggacaaa
     3241 aatcagggct cgttgttctc ttgccgcacg gctatgaagg gcagggacct gagcattcaa
     3301 gcggaagaac ggaacgcttc cttcagctgg cggcggaaaa caactggact gtcgccaact
     3361 tgacgagcgc tgcccagtac ttccatattt taagaaggca ggcgaagatg ctccttcgcg
     3421 aggagatccg cccgctgatc atcatgacgc cgaaaagcct gctgagaaat ccgaataccg
     3481 tatcagaagt gcaggagctc agcgacagta actttaagcc ggtctatgaa atgtcaggac
     3541 tttcccatca gtatgacaaa gtgacgcgcc tcgtcctttc aagcggtaaa gtttcgattg
     3601 acatcagcag tcatttcaat aaaatggaag gtgaaaaaga ttggctgcac attgcacggg
     3661 ttgaagagct gtatcctttc cctgcaaagc atattaaagc gatcttcagc aaactcccga
     3721 atttggagga gattgtctgg gtacaggaag aaccgcaaaa tatgggtgca tggaactata
     3781 tcgagcctta tttaagagag attgctccaa aggacgtgaa ggtccgctat attggcagaa
     3841 gaagacgttc aagtccggca gaaggggatc cgacggttca taaaaaggaa caggaacgca
     3901 ttgtatctga tagcttgact cgcaaaaatt aagggggaac taaaaaatgg cggaaattaa
     3961 agtacctgaa ttagcggaat caatttcaga aggaacgata gcccaatggc tgaaacaacc
     4021 gggagattat gtagaacaag gggaattcct gcttgagctg gagactgata aagtcaacgt
     4081 tgaattgacg gcagagcagt ccggcgttct tcaggaagtg ctgaaagatt ccggtgacac
     4141 ggttcaggtc ggcgaaataa tcggaacgat ttcagaaggc gaaggagaag gaggccaatc
     4201 aacggctcct caagctgacg ctcaagaaag cgccggcgct acggaagaga agccagccac
     4261 gtctgaaaag acagccgaac ctcgcgaaag cgcgaacgat gaggcggata caaccaaaac
     4321 aaggacaatc gcttctccgg ctgcccgaaa gctcgcccgt gaaaaaggca tcgatttatc
     4381 ggagattcct accggtgatc cgctcggaag ggtcagaaag caagatgttg aatcttatca
     4441 gaagaacgag cagccgccaa aagctcagcc tgaaccaaaa cgcgaaacac aggcgccggc
     4501 tgctaaacaa accgaaaatg caggtaaacc ggtagagcgt caaagaatgt cccgccggag
     4561 acagacgatc gccaaacgcc tcgttgaagt tcagcacacc gccgctatgc tgacgacatt
     4621 caacgaagtg gacatgacgg cggtcatgaa cctaaggaaa cgccgaaaag atcaattcct
     4681 tgagcagcat gatgtgaagc tcggattcat gtcattcttt acaaaagctg tggtcgccgc
     4741 gctgaaaaaa tttccgctcc tcaatgcgga aattcaaggc gacgagcttg tgatcaaaca
     4801 attctatgac atcggaatcg ctgttgctgc gccggatggc ctcgtcgtac cggtcgttcg
     4861 ggatgcagac cgcaaaacct ttgctgatat tgaaaaggat atcggagagc ttgcgaagaa
     4921 agcgagaaac aacaaattgt cgctcaacga gcttcaagga ggctccttta cgatcacaaa
     4981 cggaggaacg ttcggatcac tgttgtcgac tccgattttg aacagtccgc aagttggtat
     5041 tttgggcatg cataagatcc agctgcgccc tgtggcaatt gatgaagagc gtttcgaaaa
     5101 ccgcccgatg atgtacattg cattatcgta tgaccaccgg atcgtcgacg gtaaagaggc
     5161 agtcggcttc ctggttacga ttaaaaatct gcttgaagat cctgaacagc ttctgttgga
     5221 aggttaaatc aagaaaaaag ctttggccgc atgtacggtc aaagcttttt gtttatcatc
     5281 tgcggggcag gagaataatt gttattcttc tgcttatttg ctttcttgct ccagtatgtc
     5341 gcaagccatg agcctgaaag gttatgccaa acgctgaaaa cagcgctcgg gacagcggaa
     5401 agaggagaga agtgcgccgt tgccaatgct gcaccgagac ccgaattctg catgccgacc
     5461 tcaatggaca cggctttttg tgatgcataa tccattttaa agcactttgc caaaacaaag
     5521 ccaaggaaaa ggccgaggcc attatgaaga acgacgactg caaaaatcaa cagccctgat
     5581 tgaataatgt tttcccggtt gcctccgacg accgcggtga cgatggcgac gatgccgaga
     5641 acagagacga gcggaagcac ctgcaccgct tttttcactt gttttgtaaa gaaaaattga
     5701 acgatcagcc cggcgataat cgggagcagc accgcctgta aaatcgacaa gaacagtgag
     5761 cccggagata ccggaagcca ttcttttgcg aaaaataaaa tgagaaacgg cgttaaaaaa
     5821 ggggcaagca atgtggaaac cgttgtaatc gccactgaca gggcgatatt tcccttcgcc
     5881 aaaaatgtca tgacgtttga tgccgttccc ccgggacagc atcccactaa aatgactcca
     5941 accgctattt cggagggaag cccgagtcca taggccagtc caaaagcgag cagcggcatg
     6001 accgtatatt gaaccagcac accgatcagc acatgcaggg gacgtctcag cagctcttta
     6061 aaatcgtccg ctgacaatgt caatcccatg ccaaacataa tcacgccaag caggatggta
     6121 atataagggg tgatccaggt gaattgcgtc ggaaaggcaa agccgagaac cgcaaacaga
     6181 atcacccaaa tggcaaacgt ttttcctgca aattgactga ttttgatcaa ataactcata
     6241 agtccagctc ctcacatctg tagaaaatat aacatcctct tattataatt aatattctga
     6301 ataattcaat gcttgtaaaa ttcgaatttg ttttaaataa tattattatg taaactgaaa
     6361 gaaatgtttg aaaaccttga cgaattcgtt tatgcttttt aaaatgatag tttgtagcca
     6421 tatgcaatta gaccgagaag aagaggtgct taagtggaaa atcaacaaaa tatatggtca
     6481 tcaaagcttg gatttatctt agcttcggcc ggctcggcaa tcgggctcgg cgcgatatgg
     6541 aagtttcctt atgtcgccgg aacaagcggc ggcggagcat ttttacttat gtttattctt
     6601 tttactttat tgattgggct tccgttatta atggcggagt tcattatcgg cagaaagact
     6661 caaaaagatg ccgttgaatc ctataaggag ctggcgcccg gctcgctttg gcattggatc
     6721 ggccggctcg gcattatcac gtgttttatt ctgctgtctt tctatagtgt tgtcggcggc
     6781 tggatcatca tttatattat caaaggactg accggcgaac tgtcaagaag cacggattat
     6841 gcaggtcttt tcggagagac aattgcaaat ccgtatctcg ttcttgcgag ccagtttgca
     6901 tttatcatga tcacgattct tgttgttgca aaaggagtca gaagcggaat tgaaaaagcg
     6961 agcaagttta tgatgcctgc tctgttcgtt atttttctgc ttttgatcat ccgttcgctt
     7021 acacttcccg gttcaatgga aggattggaa tttttcttaa aacctgatct ttcccatatc
     7081 acagccaaaa cggtgctgtt tgcgcttgga caatcctttt tctcgctgag tgtcggtgtt
     7141 tccgttatgg taacgtacag ctcttattta tcgaaaaaag aaaaccttat acagtcggcc
     7201 gtttcagtga cattgctcaa tgtatctgta gcgattcttg ccgggtttgc gatttttccg
     7261 gccgtttttt cattcggatt atctcctgat gccggcccga tgctgttatt taatgtgctg
     7321 ccgtcagtct ttcacaagat gcctttggga atcgtctttt tattggcgtt tctgctctta
     7381 tttttatttg ctacactgac gtccgcattt tcaatgcttg agatccttgt ttcttcctta
     7441 tcaaaagggg atcctaaaaa aagacaggct ttcgcttggg ccgggggaat tgcgattttc
     7501 ctattcggaa ttccttcagc attatcatat ggcgtgcttc aggatgtatc gatttttaat
     7561 ctatctatat ttgatgcggc ggattacctt gtcagcaata ttttaatgcc gctcggcgct
     7621 ttgctcatcg ccgtttttgt gccgctcaaa atcccgaaag aagagctttt tgctgaattg
     7681 agggagggct ctaaaatcag cagaaaatgg tttgcagcat ggcttttgct gatccgctac
     7741 gccgctccga tcgttattat tgtcgtcttt ttggacgtca ttggcgtatt ttaaaattga
     7801 attgtttata aggccggatt tgtccggcct ttttttcatg cagacagttt gtcaacggta
     7861 ctttcttttc tctctgtgaa atggcagcgg tatgaccggc aagggaagtg tttgattaat
     7921 cggctttttt ctgcgcagac atattaaaaa ggcctgccgg tgaattcgtt tttgacgatt
     7981 ttaccggcag gcagaagagg gggatacttt gactttgatt aaggcatgcg gaatgttaca
     8041 gtttggccgt ttcgatcaaa ccagccttta aaggcccagt taatccagcc gccgtctccc
     8101 tggtttgtaa attgtccgct ttcaaatacc caaatgccgt aaatcacgcc atgatagttg
     8161 gcagatccat aaaattttac tcctcttaaa ccattttgat agccttgact taagttaaat
     8221 accatgacat tgtatctttg cccagcagaa taaaaagcgg tttccatgca gtttttgacg
     8281 aaaccgctgc ggttggagct ttgaacgata gcatctctaa tcgagtttcc gattcctaaa
     8341 agatcgaggt tgatgttgag attaatagcg gaagttttaa actgttgttt ttcctggtcc
     8401 aatgactgat tgagagatgt gggtatagac atagaaggca aggttgtaac agaactgtcc
     8461 gtatgctttg attctttcgc ttctgataag tacggcaaac aagtcaaacc gagcattaag
     8521 gctgtaaaga aagcaaacat ttttttcatg attaaccctc ctaaaataaa tttgccattt
     8581 tcgaaaaact gaccggctga atcagacaaa catcgacagt ttattcattt attccctccc
     8641 ttcttgtaga atagcttaac gagttttgga attagaagaa tgaggaaaaa cgactatttt
     8701 ccaaataaat caaaaaatgt tcacattcca tacttaaggc acaaatttgg gatatattga
     8761 tagactgttg agattcagta tttcataaag ggatgatcaa aatagcagat tcagaaggat
     8821 gtatggttgt gggggttctc ttccgacccc tccttgccaa tctccgtgta gcggccttaa
     8881 caatcctcaa gagaaactgg gatatttaaa cttttatttg ttatcttatt acagacgata
     8941 gagggtttaa gggatataga tacggtattg agagtgataa ggtatcggca ctttcgctcg
     9001 attcggccag tgtcgacggc tgcctggcgc agagaagaga aaggtgcgag aggaaaggct
     9061 cgtccgcttt ttgaggcaag gctttgacgg ggaggccgat gtcgggcgca actaccgaaa
     9121 caaaagagga cttcagtagt tgaagtcccg ccattgaatt tgaatcagaa gggctcccat
     9181 agaacgcgct ttgctgtcgc aaaccgcctt tcaggttctc tccagtcaac gacattccac
     9241 caattatcga cgtattttgc cctttcattt ttatattgaa ggtagtatgc gtgttcccat
     9301 acgtcgagcg ggagaagggg gatcacatcc cattggctca tcagctgatg tttttctgcg
     9361 atcagaattt ccaagcggtg tgagcgaggc gcccagacaa ggatcgccca gcccacgcct
     9421 tccacctttt tcgccgcttc ggaaaattgt tctttaaagg ccgaatagct gccgaaagaa
     9481 cggttaatca tttccagcaa ttcgcctgtc ggccgccttt ttccttttgg atgcatcgcg
     9541 taccaaaata tcgtgtgcaa atagtgcccg gctccgtgga aggcgagctc tctttcccag
     9601 tggtttacaa ggtcgaattg tttggtttgc cttgctttct gcagttcttt ttcagctttg
     9661 ttcaagccgt cgacatagct ttggtgatgt tttgtatgat gaagaaacat aatttctctt
     9721 gaaatataag gctcaagggc tgaataagag tagggcaggc ttggcaggcg atggcctccg
     9781 atcggcactg ttctgaatgg ctgccggcct gcttgagacg catcactgcg ggagatggct
     9841 tgatacacgg cttctgcctg ttcataccat tcctgttcgg tcgcacgagg atcatccagt
     9901 gattgaaaaa gtttttctaa ctggcttact atagaaggat catctttcat ctggtctttc
     9961 agacctttgg cccatgacgc tattttttct ttgtaagcat tcaatatgtc tccctcattt
    10021 ccgctttttt aataaatgcg cttgaagcga gcaatgaaaa cacaaaagga taactgtgat
    10081 agcggatgta gaattgtttc ggcagaccga ttcccgtcgg gtattcgagt cgctcaggcg
    10141 agctttcgtg atcagcggtg agaaaacgaa tcccttttaa gatcttaggg tcatccggac
    10201 gctcatattg caaaagcgcc tccagcgccc atgaagattg aacaactgtt ccaaagtgaa
    10261 gagggacaaa acgcttcgct tcacagcttt tgcaagattc tccccagctt ccgtcttcaa
    10321 gctggatcga tttaagccag gagaccgctt ttctgacaga cgcgtgattg tgggaaattc
    10381 cgacggcttt cattccggtg agtgcggccc atgtcccgta aataaagcag acgccccatc
    10441 tgccatacca cgaaccgtca gcttcctgat ggtgatcaag ccaccttaga gcgcgtctga
    10501 ctgcgggatg gtcatctgtc aaccgctctt taagtccgag cagatgaaga atgcgcccag
    10561 tcaagtctgc cgttgacgga tcgactgctg cgtcagcggc agattcgagc ggcagatttc
    10621 ggatgagcgg atggtcaacg tttttttcaa atgctgaaaa ccccccatcc ttgttttgca
    10681 ttgatataag ccaggtgagc ccccggttcc aggcagccgg acgcctttga aacggaattg
    10741 cttttaatgc cgcagcggta tcgtccaaat cgggattgtt tgtattgatg tgtgaaaaac
    10801 cccaccctcc cggtgccgct tgagggtttg agaccgccca gtccgctttt ttcacatgct
    10861 gtcttttgag aaggtagtcc gctgccgatg agatggaaga atgttgttca ggtattccgg
    10921 attcctgcat ggcaaagctg atgagcgcgg tgtcccagac agtggaagtt gagttttcca
    10981 aatggaagcc ttcctctccg catgaggaaa taaggctttt gattccgccg actgcttttt
    11041 taacaacggg ggcgtttttt gatattccca tcgctagcag gctgtaaatc atgaacatgg
    11101 tcgcgctcgc atagctgtat agtgttccgt cttcttcgat tctgtccagc atatattttt
    11161 tgcccgcttc aaatccgagc tgatgaacat aagccggcca ttgaaagagc tgtttccatt
    11221 gcagattgaa agaatagaag gttctctcgt caaaagagcg gatgttcagc cattcgagag
    11281 gattttttga catggcttca tccagatgcc gaagcgagcc gatttggttg ttttttaaag
    11341 agaatcgtcg attaaacgta atggccatcg ggacaaaatg aattcttgcg tatgtgctga
    11401 aatggtaaaa atgaagcggg aaatagggcg ggatcagtaa aaacgaaagc ggaatatagg
    11461 ctctcggcca tggatacagc ccgttggcag cgagcatcca cttcgtcata aagtgcacat
    11521 tcttcaaacc gcctgttgcc ttaataaacg cctcggcttt ctgcatatgc gcatctctcc
    11581 ggtcatagag ccccgaagcc agcatcccgg tatagccctg gactgtcgcg gtcaaattgc
    11641 ctgccgtttc atccggatga ttgcgaaacg caccgtctcc gctctgcttc gaacggattc
    11701 gttcagcaag acttgtgatg agagaagagt cctgatcgcc aagtgaggtc agcatcaaaa
    11761 tgaaaaagct gtctgtcatc acgggccctt caaaacaaaa ccgccatgac ccatcaggtc
    11821 tctgtctatt ttgaagcttt gcgagcgtct tttgtctgaa agctttcacg tcttctagta
    11881 aagaacgcaa tcttctcatc tccttcattt tactgtattc atttcggaaa tgtgtcatgc
    11941 caaccggatg aaaacagaag aacagcgatt ttgaatatgt gatgagcata cagaggcatt
    12001 cgtcagcgcg ggcatgcgtg agcatgatca ggaaatcatg aatatcttcg tttacctctg
    12061 ttccattatc aggtattgta aaaagagaga ccttagaaac aatgtttggg ggatgttgct
    12121 gaatgaatat tgaacagatg ctgtatgaca ccgcagtcga attgatcaaa aagaggtatc
    12181 cgaccggatg gggcggggca gctgccatgt ataccgaaga cgggagaatc ttgacgagcg
    12241 tagcgccgga agtaatcaac gcttcaaccg atttatgcat tgaaacgggc gccattctcg
    12301 aagcccataa atatcaggca aaaattacgc actctgtttg tgttgtgaga gatgatgaac
    12361 attccgaatg caaggtatta acgccgtgcg gggtatgcca ggaaagactt ttttattggg
    12421 ggccggatct taaagcagct gtaactgtac cggatgggcg tctgctttat aaatctttaa
    12481 aggaaataca gccataccat tggtttgctg cgtatcaaaa gtagcagggg aggggcgttc
    12541 gatgtttgag tgccgcaagg tttatctcag acctgttgaa aaaggcgata tggagagctt
    12601 ttacaaagct gttcaaaatg aagacatcag atatatgacg ggcacgacgc gcgaatttac
    12661 gatggaagac ctttatgagc actacgagag aatcacaagc gatgagacgc gctatgattt
    12721 tgccgtctgc ttaaaggagg acgatcgttt gataggcgat ctgtccatca ttgacatcga
    12781 ccggacgaat cgaaaagcgg ggtttagaat cgctttgcac agccccgctt atttgaacaa
    12841 aggctatggt tctgaagcgg tgcggctggc catgcagttt gcattcgaaa ggctcgatct
    12901 taaccgcctt cagctcgaag tcttttcaca caataagcgc gcgctgaaag catatgaaaa
    12961 agccggattt aaaagggaag gtacggtcag ggaggctctt tatatgaata aacagtactc
    13021 agatgaaatc attatgggga tattgaagcg ggaatacgaa gagctgatat cccgctgaat
    13081 cagagggcgc gcagcatgtt attctactga gcgccgcttt gttcattctt atttttcaat
    13141 ctttgctgaa cggctgtaaa tgccgccggc aatcagcgcc attgtcatcg aatatccaca
    13201 gcagcttcat cgttctattt gccttgcaga ctggctgtac gttctcacat cccgcacgaa
    13261 aaatgtgaca gcggctgttc cggcatataa tacagcggca gcgataaata cgctttgcac
    13321 cccgatcaag tccgccaaag cccccataat ggcgattgtt aagacagacc atgcagtcaa
    13381 aatagtattt ttggcggcgg tgaccggtgc acgctcttca tctgtcaacg tatcttgaag
    13441 gataaccgtc tggctgacgt ctcttacttg ataaagcgga cccatcatga tacagaggat
    13501 gaccgaaagg aggggatttg acgaataggc gaataaaagc gttgtgattc ccattgaaac
    13561 agaacccaag acaatcatga ggccaagcct ttttttgagc tggttggaaa agagcacagc
    13621 gagaatgccg cccaaaatcg ctcccaaaaa ataaccggca ttgatgaatc cccaccaagc
    13681 ctccccttta tttagcacct ctttcgtaaa agccagcaaa acggcggaag tccagaccgc
    13741 atttgctaaa ccttctgaca tgtccatcat cgtaagcagc aaaacggttt tcttcctgta
    13801 tacagtgcgc cagactgatt gtgtgcgggt tttttgacga gggataacag ctgttttcaa
    13861 atccggcaat ttgattaaaa gccctgatac gaaaaagagt cctgctgtaa acaatgtcag
    13921 cgtgtgagtt tgggccaaaa cggttaaata gccgccgagc ccccagcctg ctgcctgaac
    13981 aaactggttg accgttacga tgcttcccga tgccgccacg taatcgcgct ttttaatcgc
    14041 ttgatacagt aaacctaact gtgcggggga ataccaggaa ccgacaaagc tttgcaaaaa
    14101 cagcagcaca taaatgatat aagagggtaa gcccagcgat tggcataagc cgatgcataa
    14161 tgcgcagacc gctctgaacc atgttgaaca agccgctgtt tgaagcaggt cgaggcgctg
    14221 aatagcaaaa gaagccatcg caccgcctaa tacactgccg aacgaggata aagccaagac
    14281 cagacccgat ccgaatacag agttcgtttc cttaaacaca tcgaccatga cgatgatcgt
    14341 catcaaaatc gacccgacag cctgtgctgt ttgtgatgcc catatgtatc taaaactttt
    14401 ttgattccag agggttttgc caagagagga agaaaacacg attctatcat tccattcgac
    14461 ttaaactatc atccatttta ccatatgtgt ctataaatgt ttatttctat aaaaaagaaa
    14521 accgccctga tcgacagggc ggctgcagaa actcatatcg tgcgttattc gcctgtatga
    14581 atccagacgc tttttacttc tgtatagtta tccagagcgt atgagcccat ttcacgtccg
    14641 agtcccgact gtttgtagcc gccgaatggg gatgcggcgt caaaggcatt atagcagttg
    14701 acccaaacgg taccggcttg cagacggtcg gcgatatagt gggcgttttt caaattttcc
    14761 gtccatacgc cagcagcaag gccgtattcg ctgcgattgg cccgttcgat gacttcatct
    14821 accgtttcat aagggatcgc cgccaaaaca ggaccgaaga tttcttcttt tgctattgtc
    14881 atctcgtctt cgacattggt gaatacagtc ggagaaacaa agtatccctg ctcataaggg
    14941 catgttccgc cggctgcgat tttcgcacct tcctgacgtc ctttttcaat atacgagagg
    15001 acgcgttcgt gctgctcttt gctgacaagc ggtcccattt gcgtgtcttc atgaaggccc
    15061 gcaccctggc ggagcgactt ggaatatgcg gccatttcat cgacgacttt gtcatattgg
    15121 tctttatgga tgaacacgcg cgatcccgca cagcacactt ggccttgatt gaacatgacg
    15181 ccggttagtg cgcctggaat cgctttcttc agatcggcgt caggaaggat gatattcggc
    15241 gactttccgc cgagttcaag ggtcacccgt ttaaccgatt tggccgcttt ctccataatt
    15301 tttttgccga tttccgttga ccctgtgaat gccagtttgt cgacaagggc atgatcggtc
    15361 agagcttctc cggccgtctc accgaagcca ggaatgatgt tgatgacgcc tttcgggaag
    15421 cctgcttcat cgatcagttc cgccaaatac agagcggaaa gcggcgtttg ttccgccggt
    15481 tttaagacaa ccgtacatcc ggctgcaaga gcggctccca ttttccacat ggccatcaga
    15541 agcgggaagt tccaagggat aatttgcccg acaactccga caggctcatg tcgtgtatag
    15601 ttaaaataag gtccgttaac aggaatcgtc tgtccggtta ttttcgtcgc ccagccggca
    15661 taatagcgca tatgttcaat tgacagcgga atatcgcctg cggtcgtttc gctgatcggc
    15721 tttccgttat ccagcgtttc aagctgagcc agttccgttt tgtgttcctc catcagatcg
    15781 gcgagtttgt acatcagccg gcttctttcg gccgggttca tcgtccgcca ctcaccgcgg
    15841 tcaaaagctt cccgcgcggc tttcaccgct ttgtccacat cctcgggacc tgcttcatat
    15901 aaggtggcga gcgtttctcc agtcgccggg tttggggtct caaacgtttt gtttgaggcg
    15961 ctggctacaa attccccgtt aatatagagc ttctttgttc cctgcaaaaa tacctccagc
    16021 tttttactga cctgcattgt taatgaactc atgtttgtca aacaaacctc ctttgaaatt
    16081 ttggtctgtc ttcgggtgag ttgtcttggt gctggtttgt cttttgattt ggtcattgcg
    16141 cggatgaaag agggatatat ttctgatttt ggaactatac accaccattc tataacaggg
    16201 aatgaaacca aatcaatatc catgctcttt aaaatcacat tcgcctccag atcgcattgc
    16261 atttcggcga aaaaacgcta caatggaaac tatacacgta tgaaaaagga gacatccgca
    16321 tgattcacga aaaatggcag aacaataaca ccattaaaaa agtaaagtgc atacataccg
    16381 atgccaaaaa gtacatcgtc aacagagcgc tgaccgtagg caacgtatac gaggtcaaaa
    16441 acgaaacgga agagtttctg tttatcatcg ataatacaaa caaagtcggc ggctattaca
    16501 aagagtactt tgaagaagta aaagcctgaa tcaatttgca cgggtcatca acagcaatga
    16561 atgggagttg aacatacacc cgcacgcatt cataaaaaat cggctgactg aatcagttgc
    16621 ttgaccgaag cagaagcaag tgcctgatat gtgcatttca ggcataatag tcagaagaga
    16681 accgcagagg aagaacatcc tgctgcggtt ttttgtttta tccgttatcc accttttgat
    16741 tggtagcaaa cgaaaaataa gctgaaaaaa ctgataaaaa gttgaaacct cccgcgtccg
    16801 ccgggcgtat taattgatag taaaaacaaa catatagcgt taaagaaatg taatctgctc
    16861 gtaattgttt ataaatcagg gttatcgtat ccttattagt aactgacaag tatactttgc
    16921 cttgtgcata aacataaatt ggatatacag aaagaggggt tttgattggg cgttttttca
    16981 gcaagcaaga cagcagacgg caaaaaattt gaaccgctgc tcatagaagg agaaaaaatt
    17041 gaatcggttt gcagactgag gatagatcaa atttgtttta cgaacaagcg gattattttt
    17101 tttgataata aactgttttc caaaaagaaa gtccgcgtct ttctgccata cagatcgatt
    17161 gaaggctttg cgattagaga agtcagcatg ttcaatccag acagttctct ttctctgatg
    17221 accagcagca aaatctttga cctggaattt acgaaggata ccgacatgct tgaaattcaa
    17281 gcgctgttat caaaatactt atgtgcataa accgtaaagg ctgttcaccg cttgcccgcg
    17341 tctgaacggc ctttttattt tggaaaggcg ggtttttctc ccacgaaatc gggaaaggaa
    17401 gaagaaagga ggaggatcag ccatgccatt aacacaaaaa caaaaagacc atctctacca
    17461 taaattaatt gacttaaaac aaagcctttc ccctgcagaa ggaacagatc agtcgatggc
    17521 ggaagaaacg ggcgagcttt caaacggagt tgacaatcat caggctgacc atgccagcgt
    17581 ttattttgaa cgaatgagag agcagacctt ccggcagacg gacagaaatt tattaaaaga
    17641 agtggaagac gccctcaagc gattggaaga cggcacatac ggaatatgtg aagcaacagg
    17701 tcaagaaata ccatatgagc gcctcgaagc cgttccatat gcaagaaaaa ccgcggagac
    17761 tcaagctgaa acagaaaaaa gaaatcaaga gggggaagga tatgacgagc aatttacacg
    17821 gcaaatgaag gatttgacaa acagagaaac gatggatcaa aagcgttcat atgcttacga
    17881 acgtcttgat gaggagcagg attcaaaata agcacccgca aaaacagggt gcttttttct
    17941 atggctctgt ttgttaaaag agatgtccta caactgtcga cggggagtca agtactcgac
    18001 acaataaaac atttatcagt tatcggaggt ttaattgcag ctattgatat tctagagaaa
    18061 aatccggaca tccaggaaaa gttacacgaa aacgaaaagt acttaagaga cggcattcaa
    18121 caaataggtc ttaatgtatt acatagtgaa tcacctatta ttccaattat tcttccagat
    18181 cgcgacacaa ctttacgttt tgcagactca cttcatcaag aaggtgtcta cgttaaccca
    18241 attctcctct tcgcatacct gtttctaaag ctactaagac gagcacatga aattcttcct
    18301 ctgtgtgtgc tagtagatat gttcttagct tttggaagtt ggtaatggat aacgctttgt
    18361 ttcgtttcga taactctttc ccacgaggtt tgacaagttc tgcgaaatca ttcgtgagat
    18421 aaccacgagc gtaagcgtca cgaagtgcca ttttgacttt tattaacaag ctgcgagtgg
    18481 tactgtgaga acgcttcttt gcgtattcat caatttttct ttgcacagca atgtcattca
    18541 tatcttttaa ctgaatattt ccgaataact ttctaataat ccctgacgct tctaggtatc
    18601 tttgaaacgt agctttttgt atatcatttt tcttcacaag atatatccag tgttagttgt
    18661 ttaaaagaat ctacatgcct aagtcaaatc tctttgtttc ttccatcaat ctgatataaa
    18721 agtctttttt tatcaccttt tttatccaat tccttgatat gtccgccaca aaattccagc
    18781 acaggacatc atttccctta ccgtatcaac ggattccata ctattattct ctatttccta
    18841 cctccctgtt agatatggag aggtagaatg gtgtcgttgc tacgcaacga cacgcacacc
    18901 gcttccactt gctcgctttt gctgctgctt gcggaagcgg tgtcacttcg gcagtttttc
    18961 ataatttctc catgcactca cttccattgt gaaaaatgaa gcactatttc tatttatctc
    19021 gctaaccgtt cgtattcggt atctcggcgc ttatcaatcg ctctggaata ggcttccatc
    19081 atggcgatat atagtagatt gtttttacaa tcattagtct acataacagc ttttacggtc
    19141 aatactgctc gctgttttat caactacaat gtttagagac tgcttgtatg tctcgcttga
    19201 aacaagtcat cttagggttc cattcatgaa tgtagtagtt tcaaacttct gtatttagtt
    19261 gtatgggagt atttttaaat aattcctttc aaagacagct tatgaagtga tttttcgcat
    19321 gtagaaaggt tttagtatgg ctattctcac aaaataaata tcacgatatg caatgttgtt
    19381 ttttaaaaaa atagctcttc atacatcgct ctttctcatt tttattttct cgcttgctaa
    19441 gtttctgtct atatctttgt tacggttaat atcatattac gatttgtatt ggagttgtag
    19501 gggggggtgc aaaataaatc tttatttgtt caatgttatt atcgcatgat gtgttgtgat
    19561 attgtgtaat atccttatca tatcaactat tagagaggga gaaaaaagta tcaaattctg
    19621 caatgaaatt cttgctgcaa taaaattctt gcggacatat tgtcataggg gcataatcga
    19681 tgttgagtga gagacagaac gccgataaag tataatatct ggatataaaa cgaagaaaca
    19741 attgcttgat ggattgtaga catgaaagca ttgaatatac acctatcaaa atcttttaca
    19801 ttagcagaaa aataaggaga tttacatata atcatgttta atatgtaaat ttctctatta
    19861 tgtttatcaa agataaggta atagttttta cgtactgcgc cataacttaa tctatctttt
    19921 tccattttat taatctcatt acatattcag aaataacctt ttcccttgta taatcggtat
    19981 aatgtgtctg ctttgaaatg aaaaaatata gtggcatcat gatcacagat agcgagtcaa
    20041 tattttatta ctgggggtgt ctcatgggaa gtaagatgat aattataaca ataatcacag
    20101 tatttatgtt gtttgttgga tttaacacct cagcctatgc attgacagag gaagagtctg
    20161 ttgcaatcca atcattatta gaagatgcta ggcgtatatc tggcacaccg ggcatgtcag
    20221 tttcaataca atcaagggat gatacctatt tcttttcatc cggctatgca aactctgagg
    20281 aagggatttt gaccaatgaa aacaccatat gggagttagc ctccgtcagc aaagctttta
    20341 ctgctttagg aattttactt ttggaagagc agggattttt gtctatggac gattcggttg
    20401 tagagtattt accttggttc tcattgcgat atcagggaca gcccgttgac atgcagagtg
    20461 ttactttgaa tcatttcctt catcatacta cagggttaat caataggtat catactcagc
    20521 atatcccaga gggaaataca ccagatatgt tgcaaaagac cgttgaaatg ttaatagatg
    20581 ccgaagtggt atttccacct ggcgaaagat atgaatatgg gacggtaaat tatgatgtgc
    20641 tgggcttggt gatagaaacc gtatcggggc aaagctttga ggattttatg gaagaacaag
    20701 tatttcgacc actggggttg tatgaaactt atgcgaatag aggtaaggta caagcgacag
    20761 gtcagttggc acagggctat cgttccgctt ttttcatgac gctgccatat gatgcaccgg
    20821 aatttagagg aaacacacct gctgggtatc tgttttcgtc ctctcaagac atagcccgtt
    20881 ggatgggaat tcaattggga attgttgaag atattccgga aatctttcaa gggctgattg
    20941 caaaatcaca tgagggcaat aggtctgttg cggctgtgga tgaactgtac tatggggcgg
    21001 ggtgggtcgt gaatgcagat cagacattca tccaacacgc aggtggtaat ccaacgtttg
    21061 caacaaatat attcttattc ccagaagaac agctaggtat ctctctatta tccaatagtg
    21121 ccagtacaaa tattgatatg ttatataata ttaaggatat tttagacgga aacatctccc
    21181 aaagctatca aatgagtttg atgcagattt ccgatatcgc cctatcttcc gctacaattg
    21241 ctctaacatt actagcaatt ctatttttct ttttaggggt gcgtagaaag aaacagaata
    21301 ggaaattacc gttaacgaaa aagagattga tactcatagc tttttggctt gtgactacaa
    21361 tttttatagg tatcctatgc ctaatcctcc ccacaatatt tggggctagt tggaggtcat
    21421 ttctagtttg gcaaacgtat agttatctaa ccgcactgat tgcgttgtct ttactaagtg
    21481 caagtatcac ttggtttgta tattgttatc gatataaatg ttcctaatga gatgtgccat
    21541 tgtaacctaa acgaaaactt ttttatttgc ttcgcagcat attcctacca cgcataaata
    21601 tgctacataa tataatgttt tatgcttgaa cttaaataat gttgtattat ctgaacgaaa
    21661 gttcttgctg atatgagcaa tcgtttgttt tttatcaaat atgaacaggg cttttttgat
    21721 agaaacatct tttggcatca aaataaatga gttgactttc tatttaaaag aaagtaacat
    21781 actatttgta agtaaatatt gaaacgttag cacgggagga aaatagaatg tctaaagtat
    21841 tgtttgttaa agctaatgac cgtactgctg aagaagctgt atctgtaaaa
//
