LOCUS       NZ_NKBC01000011        28169 bp    DNA     linear   CON 17-MAR-2024
DEFINITION  Bacillus paralicheniformis strain 9-1 9-1_R1_(paired)_contig_11,
            whole genome shotgun sequence.
ACCESSION   NZ_NKBC01000011
VERSION     NZ_NKBC01000011.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus paralicheniformis
  ORGANISM  Bacillus paralicheniformis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 142874)
  AUTHORS   Cui,Y.
  TITLE     Improper usage of probiotics constitutes a potential risk of public
            health
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 142874)
  AUTHORS   Cui,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JUN-2017) Beijing Advanced Innovation Center for Food
            Nutrition and Human Health, College of Veterinary Medicine, China
            Agricultural University, Yuanmingyuan West Road, Beijing 100193,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 9.5.3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 20x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009935535.1-RS_2024_03_17
            Annotation Date                   :: 03/17/2024 02:24:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,539
            CDSs (total)                      :: 4,461
            Genes (coding)                    :: 4,361
            CDSs (with protein)               :: 4,361
            Genes (RNA)                       :: 78
            rRNAs                             :: 4, 1 (5S, 16S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 68
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 100
            CDSs (without protein)            :: 100
            Pseudo Genes (ambiguous residues) :: 0 of 100
            Pseudo Genes (frameshifted)       :: 49 of 100
            Pseudo Genes (incomplete)         :: 64 of 100
            Pseudo Genes (internal stop)      :: 15 of 100
            Pseudo Genes (multiple problems)  :: 21 of 100
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:47:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 114705
            Orig. end                         :: 142874
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            NKBC01000011.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..28169
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..28169
                     /SMILES="NC(CCC(=O)N)C(=O)NC(CC(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..28169
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[20000:>28169](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..>28169
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     misc_feature    269..283
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.65"
                     /tool="antismash"
     gene            306..1262
                     /locus_tag="CE036_RS11730"
     CDS             306..1262
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178789.1"
                     /locus_tag="CE036_RS11730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acetylxylan esterase"
                     /protein_id="WP_023855676.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 5.9e-11, bitscore:
                     35.2, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQQPYDMPLEQLYQYKPERTAPADFEEFWKGSLEELSNIKAEPEL
                     EPHEYPADGVKVYWLTYRSTGGARIKGWYAVPDRQGPHPAIVKYHGYNASYDGDIHDIV
                     NWALHGYAAFGMLVRGQSSSEDTETSQHGHVPGWMTKGILDPKTYYYRGVYLDAVRAVE
                     VVSGFAEVDEKRIGVIGASQGGGLAVAVSALSDIPKAAVSEYPYLSNFQRAIDIAIDQP
                     YLEINSFFRRNTSPNIEQAAMRTLSYFDIMNLAQAVKAPVLMSIGLVDTITPPSTVFAA
                     YNHLKTDKEIKMYRYFGHEYIPPFQTEKLAFLRKHLK"
     gene            1349..1777
                     /locus_tag="CE036_RS11735"
     CDS             1349..1777
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178790.1"
                     /locus_tag="CE036_RS11735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="winged helix DNA-binding protein"
                     /protein_id="WP_025810789.1"
                     /transl_table=11
                     /translation="MKMNTEKIIEMMNQDWTDIYYHLHTKHDDHLSHHAVRMLQHIEKN
                     RLVTIGHLAKLLDVSHNTASEHVKRLIQKGLVQKNRDSSDERKVYVTLTPEGEEAVKRH
                     TRLHPKKLQKVLEQLNEEEVEMIKTAFSLLSREAKSCF"
     gene            1768..2109
                     /locus_tag="CE036_RS11740"
     CDS             1768..2109
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178792.1"
                     /locus_tag="CE036_RS11740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF3147 family protein"
                     /protein_id="WP_020450088.1"
                     /transl_table=11
                     /translation="MFLIVKIGVSAILIAIITEIARKSPEMGGMIAALPLVSLLSLFWL
                     SVQGESLKHLSQFAKGVLWGFPATAVLLLIVVLSLKASFPVVISVVFGVCGWGGCLMLQ
                     KALIHAIFG"
     gene            complement(2195..2521)
                     /locus_tag="CE036_RS22750"
     CDS             complement(2195..2521)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CE036_RS22750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_229105605.1"
                     /transl_table=11
                     /translation="MSDKAGNPVEKNGREDLYISLVNQEAHRLKGYLYCFENGEYQKFM
                     VSQSKAQAFSYELAPETVQTYPINLKILGSHYFRFLSTSIPPEGPYRDVPFPARMIYYS
                     KLYT"
     gene            complement(3055..3738)
                     /locus_tag="CE036_RS11750"
     CDS             complement(3055..3738)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178799.1"
                     /locus_tag="CE036_RS11750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_020450090.1"
                     /transl_table=11
                     /translation="MGSIQWEYIFNAELAAKSFPYVMQGIWNTLFISFASMFAGLILGF
                     FIALGRMSEISLLRWPARIYISFMRGVPILVILFILYFGFPYIGIQFTALTAALIGFSM
                     NSAAYIAEIIRSALSSVDRGQWDAAKSIGFSYWQTMCHVIVPQSVRIALPPLANVMLDL
                     VKASSLAAMITVPELFQQAKIVGGREFDYMTMYILVALIYWAVCSAIALLQDFLEKRTE
                     VYIKK"
     gene            complement(3750..4625)
                     /locus_tag="CE036_RS11755"
     CDS             complement(3750..4625)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178801.1"
                     /locus_tag="CE036_RS11755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="WP_026580508.1"
                     /transl_table=11
                     /translation="MNKLHTYKRITLLITVLALALITAACSTTQNKAENQKTAWDEIKE
                     KGKIVVATSGTLYPTSYHDTDSGKDKLTGYEVEVIREAAKRLDLDVEFKEMGFDGMLTA
                     VGSGQVDAAANDITMTDDRKEKFLFSTPYKYSFGTAIVRKKDLSGIHTLEDLKGKKAAG
                     AATTVYMDIARQYGAEEVIYDNATNDQFLKDVANGRTDVILNDYYLQKLALAAMPDLDL
                     TIHPDLKYYPHQQGMIMKKGNAELKKQFDKTIDEMLKDGTIKKISKKFFGGADVSKKQD
                     IDFVDVDVNK"
     gene            4809..5360
                     /locus_tag="CE036_RS11760"
     CDS             4809..5360
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0050136 - NADH dehydrogenase (quinone)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006640160.1"
                     /locus_tag="CE036_RS11760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="WP_039073173.1"
                     /transl_table=11
                     /translation="MKNILIINGHEAYPHARGQLNHTIFTAMADKLGEKYEVKKTVVAD
                     GYQIPEEHEKFKWADAVIYQTPVYWFSVPALFKKYIDEIYEYGLFYQGSEDYGRGGLFT
                     DKKYMFSTTWNAPKDVFSKEGTFFEGKSLDEALFHLHKMQEFVGMKPLKTFSVHDVISN
                     PQVDQYLADLDAHLKEVFSI"
     gene            5456..6181
                     /locus_tag="CE036_RS11765"
     CDS             5456..6181
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178804.1"
                     /locus_tag="CE036_RS11765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AAA family ATPase"
                     /protein_id="WP_020450093.1"
                     /transl_table=11
                     /translation="MFLKKLTLLREKVPSYAKYPFSIPAIQHLKELTFQKNVTFFVGEN
                     GSGKSTLLEAIADKCEFNTAGGGRNNTYEVYGSGSDLGDYIRLSWLPKVTNGFFLRAES
                     FYHFATHIDEVDITGFRGYGGRSLHEQSHGESFLSLFKHRFKEKGIYLLDEPEAALSPA
                     RQLAFLKILHDLTKSNQAQFIIASHSPILLGYPEADIFSFDGEQITEVNYEDTDHYTLT
                     KYFLQHREKLLAELFLDDV"
     gene            6251..7687
                     /locus_tag="CE036_RS11770"
     CDS             6251..7687
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388223.1"
                     /locus_tag="CE036_RS11770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="family 1 glycosylhydrolase"
                     /protein_id="WP_161517415.1"
                     /transl_table=11
                     /translation="MIHQQLRPFPNHFLWGSASAAYQIEGAWKEDGKGLSVWDVFTKIP
                     GKTFKGSNGDIAVDHYHRFKEDVALMAEMGLKAYRFSVSWPRIFPQGRGEVNEAGLRFY
                     DDLINELLAHDIEPVLTLYHWDLPQALMDEYGGFESRRIIEDFNTYCVTLYKRYGDRVK
                     YWVSLNEQNYNFNHAFITAMHPPGVKDRKRFYEANHIAFLANAKAIDSFRRYVPDGKIG
                     PSFAYSPAYPLSSRSDDILAFENAEEFTNYWWLDVYCRGTYPGIPLKYLKEKGWAPTIE
                     EGDMELLAKGKPDFVGVNYYQTITYEMNPLDGVAEGKMNTTGQKGSNQETGMPGLYKTK
                     RNPHLETSNWDWAIDPIGLRIGLRRISSSYGLPLFITENGLGEFDKVENDGTIHDDYRI
                     AYLRAHLEQCRQALNDGVDLIGYCSWSFTDLLSWLNGYQKRYGFVYINRDEENVKDLKR
                     IKKDSFCWYQNVIQTNGEEL"
     gene            complement(7727..8125)
                     /locus_tag="CE036_RS11775"
     CDS             complement(7727..8125)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017473998.1"
                     /locus_tag="CE036_RS11775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="competence protein ComJ"
                     /protein_id="WP_059230704.1"
                     /transl_table=11
                     /translation="MIKKWEAEEMTMSYHQFTVYQKGGKPPVMDWTDEDIKRGYTAGEH
                     AVSFEALDNTASLVEVRLNVQEQVPSFNRRVTVSFDVLHGGVEIASVLSKKLSCDIPQG
                     VYQLTCYTIMPDKSSTAKITYILDFKQA"
     misc_feature    complement(8108..8124)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 22.1"
                     /tool="antismash"
     gene            complement(8143..8589)
                     /locus_tag="CE036_RS11780"
     CDS             complement(8143..8589)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016936798.1"
                     /locus_tag="CE036_RS11780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NucA/NucB deoxyribonuclease domain-containing
                     protein"
                     /protein_id="WP_020450096.1"
                     /transl_table=11
                     /translation="MDKIKSLLITLLAVAVVIIGIISGDFFTSEHQPSGRQNGSDYDEV
                     LIFPSDRYPETGAHIRKAIKKGHSKICTIDRDGADERRKESLKDVPSKSGYDRDEWPMA
                     MCEEGGTGASVEYISPSDNRGAGSWVGNQVSDYPDGTKILFKIK"
     gene            8892..9062
                     /locus_tag="CE036_RS22520"
     CDS             8892..9062
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016122446.1"
                     /locus_tag="CE036_RS22520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_023855671.1"
                     /transl_table=11
                     /translation="MLRKLLKALQNGKNRRYSSSDYGRKSYKKYSSSDYKRKGYGHHHY
                     KRKHKKFFGSS"
     gene            9068..9871
                     /locus_tag="CE036_RS11785"
     CDS             9068..9871
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009330243.1"
                     /locus_tag="CE036_RS11785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="protein kinase"
                     /protein_id="WP_059230702.1"
                     /sec_met_domain="Pkinase (E-value: 6.4e-30, bitscore: 97.3,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTLMRWLFDRPLKKGTVLEGRYRINRVLGMGSYGITYLAEELGR
                     AGFRVIKQQRKTKAWTSAGRRSFNREAEILRELDLPVAPRIYEVLHAAGERFIVMEYIE
                     GKTFEDLLFYDGHVFDEQQTISILKEVLHSVSFLHRRGIIHRDLRIPNLIVSGGTIRII
                     DFGLACHLTERERVDDRHPEKRLMRAVSVKSDFYALGHFALFLLYSEFTPSGEEEKSWE
                     EELCLSSGFTSVLRKMLQIDQPYERAEDIIGDLTSCTAKKMKQPF"
     gene            complement(10195..10935)
                     /locus_tag="CE036_RS11790"
     CDS             complement(10195..10935)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178817.1"
                     /locus_tag="CE036_RS11790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LXG domain-containing protein"
                     /protein_id="WP_059230700.1"
                     /transl_table=11
                     /translation="MKVYEAETLLSAMKQRSDEYKNLREQLVSLKQSLNSVTELDEFQG
                     KGADAIKAFYRDQSGIVDGWLDLADMQIQFLNGVSAAAENAGLSEDTFVDVQFLEQELA
                     NVHIHSQNMVSAQQQELSNILGQIDDLISLQPFSSDEIKQQLDAANQNRKDTIKAVEDL
                     DGLLKREYSASEQIQQMIQSDYSALIDATGKGKNASPLNYNSHIYQNSEVYKLKQRMHQ
                     EARSYIANKQKQYETKKAEKTEEL"
     gene            11340..13394
                     /locus_tag="CE036_RS11795"
     CDS             11340..13394
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178820.1"
                     /locus_tag="CE036_RS11795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="WP_079289468.1"
                     /transl_table=11
                     /translation="MNEEGYRLGIDIGGTFTDLTLLNQADGSMTAVKTPTVPEDPAQGI
                     INGLALLKTQGVHPSEIHHFVHGMTIGLNTLLQRKGADIALFVTEGFRDILSLQRLRLP
                     IPYDFRSRMPEPLIPRKNVFPIQERMLYDGSEKLPLHKEEIDEAVGQVLRKGLKGIVVS
                     FLHSYRNPLHERQAAERIRQIAPELEVATSAELWPQMREYERTVMAVANLYIKPNVHHY
                     FRTLKERLALEGISAQPFITQSNGGLMDIESAAEAPVKTLFSGPAAGVIGAIRTAETAG
                     EANIITFDVGGTSADISIVEEGEPTFTQSNQISGFPITIPSVAMYSIGAGGGSVAWIDS
                     GGLLKVGPESVGSDPGPACYGKGTKAALTDAFLICHYLNPNRFASGNMKLYRERSEKAL
                     LPVAEYLGTDVEQAADQMIQVALANMYTELSNVMEQNGFDPREFSLMAFGGAGPVTANF
                     LAEEIQAKNVLIPPHPGTLSALGALTADFIYDAVCSRQVLLEQIKTVELKAEFVRLQEQ
                     AETWLRKQQAEMLPETSLLYLLDARYKGQAYEIELLVSPECLEGKSTSEIADSFHLLHE
                     KQYGHSDEKASIELMNIRVRIIGKTPKPPGGKGGRSELPEAEPVSQRKIIIKGGTYQTA
                     VYQRSDLRCGQRINGPAIVEQDDTTTLILPNWSGKTDHAGNLIIERKES"
     gene            13397..15391
                     /locus_tag="CE036_RS11800"
     CDS             13397..15391
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009330237.1"
                     /locus_tag="CE036_RS11800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hydantoinase B/oxoprolinase family protein"
                     /protein_id="WP_026580512.1"
                     /transl_table=11
                     /translation="MRTDPARLEMMRSYFNAIAAGMGHVIERTSFTTFVKESADFATAL
                     ATPEGEFFVYPKTVGVTIFLGLSLKRIIEESGPFEPGDIILTNDPYTTDGLATHLPDIH
                     VVKPIFMEGEVISYAWCFVHCSDVGGLVPASISPTATDIHQEGLRIPPVRIYKAGRENR
                     DILNVLRANSRVPDLNEGDIHAMVAAVNTAENRLTEMVGKFGKEAVQQGMDDLLEQAAM
                     RAGRVISGIPEGTYSFSDYLDDDMISDVPIRLAVTANVSGGEITLDFSDCDPQVKTAFN
                     LVTNGSKHSFLFQGLINFIISEDPYIPVNGGLTRPIKVIAPKGTLVHPEYPAAVGIRHS
                     ITMRLYNAVLGALAKALPKAVPAAGAGQSAIVVLSVPGESTGGRKMSVVEPMGGGGGGQ
                     HDMDGADGIDHASGFLKNTPIESLEQHIDIHVRRYELIKDTAGAGFHRGGHAIGLEFEA
                     TAPESIVTARGMERMRFHPWGLAGGTAGALGRVRLYPEQPQEKTISKIDVLKLNKGDVI
                     SIHSPGGGGWGDPYSREAESILREVESGLLSPEAAYHQYGVAVKENDAGSFIIDLEETA
                     EIRKKKAGEPRKHWDFGLAREEYERCWTEEASSTLARILRQLPAHQRSHVKHLVHRYFS
                     KEHNGSISKGDVAAAVEKLAGKNNTGMVR"
     gene            15394..16476
                     /locus_tag="CE036_RS11805"
     CDS             15394..16476
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178823.1"
                     /locus_tag="CE036_RS11805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_023855668.1"
                     /transl_table=11
                     /translation="MKSKISALFILSLVAVLLLSGCGGKGSQESKQSDTVVIGVYGGDW
                     EKHIKPSLESFEKETGLKVKVVAGTDSEWFTKLKAANGRNAPYDLLILQPDTIHRAQSA
                     GLLAPIDQEKVPNVRDLYHSVQKRFTDDGKQYAAGFSMGQLGIVYRKDLVPQEPKRWTD
                     LWNSSYKGHVAISSPAYSAGLQFFVGLINAQGGLESNGKDVDKAFNSLTDLKNNITAYP
                     DNPGSIQTLLERGDAWVVPFWDGRAFSLQDAGLDLGFAYPEEGAVAAVASWALMKGSPN
                     QDNAYKLLNHLLSPKVQGDFADRTFYGMANKKVKYSDKLKGKIKVGEDYYRNLKWVDYE
                     VAAKDLGDWTNRWNQVLGGK"
     gene            16486..17604
                     /locus_tag="CE036_RS11810"
     CDS             16486..17604
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009330233.1"
                     /locus_tag="CE036_RS11810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_020450102.1"
                     /transl_table=11
                     /translation="MSAIQIQHVSRHFGNTIALEDVQLEVKEGEFFSLLGPSGCGKSTL
                     LHIIAGFLEPTSGFVYIGGRDVTDLPPYDRHIGMVFQDYALFPHLSVFDNVAYGLKVRK
                     WPRRKIEERVMESLALVRLEAFANRMPRQLSGGQQQRVAIARALAIQPSVLLLDEPLSN
                     LDAKLRKEMQTELRSIQKRVGITTILVTHDQEEALSLSDRIGILGCGRLQQLGTPLDVY
                     RTPANQFVAEFIGQVNLLKARASKIQPSSGVYGYEAVDFEIYEGVPLTFEISRNLLKKS
                     SVLFMVRPERISVSFEKQKNRLIEMPATITEVSYAGHALRLKAAVFKGEWIIQAPDPQF
                     PRLPKAGDQVYLSLDPDDFVPLDVKEDADGCS"
     gene            17591..18457
                     /locus_tag="CE036_RS11815"
     CDS             17591..18457
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178827.1"
                     /locus_tag="CE036_RS11815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_079289469.1"
                     /transl_table=11
                     /translation="MGALEQKRFYWVLLVPVLLFLGVFLVLPLVLLLLLSFRDVDAMMN
                     TLDTYSFSQYVEVFSSDIYLKTIGITLWTALKTTVLCLVMAYPAAYLLVKAPTGRLRAL
                     FYILLVSPLLTSVVIRTFSWIVLLSQNGIVNEALISLKLIEKPLPLLWNMNAVIIAYVQ
                     VMLPFAVLSLAGSLSEMKPDLKFASMSLGAGRLRTFFFVTLPMTVPGLLTGAMIVFSLS
                     AGSYITPLLVGGRMQPLLPLSIYQQVMQVFHLPLAAAMSITLLAVVSVVIGILGFFQKR
                     WEARING"
     gene            18450..19262
                     /locus_tag="CE036_RS11820"
     CDS             18450..19262
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011197535.1"
                     /locus_tag="CE036_RS11820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_023855666.1"
                     /transl_table=11
                     /translation="MGRQLRRLSGGKWIDVCVWAAGLLVYLFLALPVFVIILSAFSPDE
                     YPKFPPSGVSLRWFAGVFSSSGWMESIWVSGMLLLVVTPLAVILGTVAAYALARLNFPG
                     KQGIQAFILSPLMIPQIALGVSFLYLLTMLGVNGTFAGLAAGHMLISLPYVLRTVGVSM
                     ANVDPKLELASMNLGAGPWYTFFHVTLPLIKPGIIAGAVFAAVTSFGEVSISLFVSSPA
                     VTPVPVRTFSYIDQTFDPSVNAISVIFITVSVIALIIIERTIGLSKTV"
     misc_feature    19498..19507
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     regulatory      19730..19816
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /regulatory_class="riboswitch"
     gene            20001..>28169
                     /gene="licA"
                     /locus_tag="CE036_RS11825"
     CDS             20001..>28169
                     /GO_function="GO:1904091 - non-ribosomal peptide synthetase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: Condensation_Starter (4-301). E-value:
                     1.6e-97. Score: 318.4. Matches aSDomain:
                     nrpspksdomains_CE036_RS11825_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (465-868). E-value:
                     4.8e-115. Score: 376.4. Matches aSDomain:
                     nrpspksdomains_CE036_RS11825_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (977-1046). E-value: 3e-26. Score:
                     83.4. Matches aSDomain: nrpspksdomains_CE036_RS11825_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1060-1346). E-value:
                     2.8e-107. Score: 350.1. Matches aSDomain:
                     nrpspksdomains_CE036_RS11825_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1511-1909). E-value:
                     8.7e-111. Score: 362.3. Matches aSDomain:
                     nrpspksdomains_CE036_RS11825_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2016-2085). E-value: 9.3e-30.
                     Score: 94.7. Matches aSDomain:
                     nrpspksdomains_CE036_RS11825_PCP.2"
                     /NRPS_PKS="Domain: Condensation_LCL (2099-2385). E-value:
                     1e-107. Score: 351.6. Matches aSDomain:
                     nrpspksdomains_CE036_RS11825_Condensation_LCL.2"
                     /codon_start=1
                     /gene="licA"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1047: phosphopantetheine-binding domain-containing
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020450105.1"
                     /locus_tag="CE036_RS11825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lichenysin non-ribosomal peptide synthetase LicA"
                     /protein_id="WP_161517416.1"
                     /sec_met_domain="PP-binding (E-value: 1.2e-17, bitscore:
                     57.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 3e-91, bitscore:
                     298.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 5e-123, bitscore:
                     403.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGNTCYPLTHAQRRIWYTEKFYPGTSVSNLSGFGKLKSASGIDSG
                     LLTEAIRQFVRTNETMRFRLLFEGGDEPKQYIAEDEPFRIEYFDASEIGGADGVLKWGQ
                     AEARRPLPLYESPLFKFAVVRISEEESWFFAKVHHIISDGISMTILGNRITDIYLKLAK
                     GETDLEPVQSSFTEHIQSELEYENSKRFQKDKAYWNAQYEVIPEPVSLKASDTYQIQLN
                     AARFSKEISPVLYKKIQTYCKEHNISVLSLFLSILHIYMHRITGQKDVVLGTFMGNRTN
                     AKEKQMLGMFVSTIPMKASIDVHQDFSAFVQERMKDQLKIIRHQKYPYNLLINDLRERQ
                     PHVSKLFAVSLEYQVMQWQRKETLSFLTEPIFSGSEVNDISIHVKERWDTGTLAIDFDY
                     REELFTCEEMAVLYERLMTLLEDALLFPQKTIAELEIVPAFEKERLLKRASSQTIAYDK
                     NMTLHGLFEQKAADHPEKTAVVYEGQKLSYRELNEQSNRLARALRRRGIGPDAPAAIVM
                     ERSERVITAMLGVLKAGGAYVPIDPGFPEERIRFMLEDSKVKVVITDSGLTFETAETVR
                     FSEALSESLENGHPSSEAGAGHLAYIIYTSGTTGRPKGVMIEHRQVHHLVRGLQQAVGA
                     YDQDDLKLALLAPFHFDASVQQIFTSLLLGQTLYIVPKKTVSDGRALSDYYRRHQIDVT
                     DGTPAHLQLLSAADDLSGVKLRHMLVGGEALSRVATERLLQLFAETAESVPDVTNVYGP
                     TETCVDASSFTMTNHADLQGDTAYVPIGRPIGNNRFYILDENGALLPDGVEGELYIAGD
                     GVGRGYLNLPDMTADKFLEDPFVPGGFMYRTGDAVRWLPDGTVDFIGRKDDQVKIRGYR
                     IELGEIESVLQGAPAVGKAVVLARPETGGSLEVCAYVVPKQSGEIHLQGLREHLSKHLP
                     DYMIPSHFVELDEIPLTGSGKVDRKALLRHEVSVSGTAEYAAPRNEYEEKMVGIWQEVL
                     GTEQVGIHDQFFELGGHSLKAMAMLAKIYKAFGVEVPLQVLFEKPTVAALSGFVSEAEK
                     DGFTVIEPAPESDDYPLSLAQQRIYIVSQLEDAGVGYNMPAAAMLEGTLDVQRLEAAFQ
                     KLIDRHEALRTSFTVVDGEPRQNIHQRVQFKIEKVKADGKPIEQMAKSFVRRFDLAKAP
                     LMRAGLVRLADRRHVLLFDMHHLVSDGVSISIILNELAALYKGEELPEPNLHYKDYAFW
                     QRTQAQKGFQKEEAYWQSVFARELPVLQLITDEPRPSVQSFEGDRVSAVLPKDMKEKLA
                     VLAEQNGATLYMVMLAAYNMLLAKYSGQEDVIVGTPAAGRRHSDLEGIIGMFVNTLAIR
                     SKVESGRTFRDFLHDVKKTVIDAFEHQEYPFERLAEKVGASRDLSRHPVFDTMFILQNA
                     WEDIPMLGDLHLSIYETNFNIAKFDLTLQAKEEQGELILDLDYSTKLFKKDTAERMLKA
                     YLHLLEGMTADPLRRIGEYSLLTEEETNRQLVAFNPAASDYPREKTIVQLFEEQAAERG
                     GHPALQFEDKVWSYGELNRKANQLARRLRERGVQPGTTAAILTARSAEMVIGILAVLKA
                     GAAYVPIDPDHPEKRVQHFFEDSGAAVLLTQKAMKPLAEAAEFGGDILFLEDEHLYLGD
                     ASDLRLPISPEAMANLTYTSGTTGTPKGNMVSHRNILRTVKNTNYLDVMTSDIVLSISN
                     YVFDAFMFDVFGSLLNGAKLVIAPKDTILDMSRLAHVLEKEKVTVLMITTALFNLLTDM
                     RPDSLKGLRRVLFGGERASVDHVRRALNTVGKGRLLHMYGPSESTVFTTYYPVNEVPDD
                     AQAIPIGKPVSNTEVLILDSFGNVQPAGVAGELCVGGDGLVRGYFNRPELTAEKFTEHP
                     FKTGEKIYRTGDMARWLADGCLEFIGRIDHQVKIRGQRIELGEIEHHLLTHEMVQEAAV
                     LAVDTGKRDQMICAYFTADQELSSEELRRYAAEGLPGYMIPSVFMQLQELPLTGNGKVD
                     RRALPEPDVTQAAQKEYTAPRSRTEAQLADLWQEVLNVPKIGVHDNFFELGGHSLIGMT
                     LIARIQQEMNVDLQLKDLFQAPTIETLAQAAEKTEKKSAIYIEAAPDQETYPVSSAQKR
                     LYVLQQIEGAEKSYHMPAVLQLEGKLDLKRLESAAQMLIKRHEAFRTTFEIKGGEPVQR
                     IWEAAELTIDVIDADEQEAEKLIKEFIRPFDLTKAPLFRMSIIRFTGEKHLLLVDMHHI
                     ISDGASVSVLIDEMTKLYAGEALEPLRIQYKDFSVWQQHLLTERHKVQEEYWLKELAGE
                     LPVLTLPADYPRPSIQTFEGSRLSFALKPELVQQLRKLAKETDSTLYMVLAASYSALLS
                     KLSGQSEVIVGSPAAGRPHTDLSRIIGMFVNTLAIRTRPEGDKPFSAFLEEVKEMTLGA
                     FEHQDYPFEELIEKLNIQRDMSRNPLFDAVFSMRNADLKDLSMEGITLKPYDFAHQTAK
                     FDLTLTAAEEDGLLVFEMEYNTALFKHESIERWRGYLLNLLEAVAENPDARLSELSLLD
                     EAEKRRIVQNWNETRLAVLEDKTVHELFEAQVLRTPDHGAAVYNGVKWTYKELNARANR
                     LARLLIEKGVRPEQRIGIMVKPSLEMAAGVIAILKAGAAYVPIDPGYPAERIGYVLRDS
                     GAELLLTQSGLTVPDTFTGDVIDLNREGSILDGELYPEDDMNPNAQAQSDNLAYLIYTS
                     GTTGQPKGVMVEHRSLVNLCYWH"
     aSDomain        20013..20903
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CE036_RS11825_Condensation_Start
                     er.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="1.60E-97"
                     /label="CE036_RS11825_Condensation_Starter.1"
                     /locus_tag="CE036_RS11825"
                     /protein_end="301"
                     /protein_start="4"
                     /score="318.4"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIISDG"
                     /tool="antismash"
                     /translation="CYPLTHAQRRIWYTEKFYPGTSVSNLSGFGKLKSASGIDSGLLTE
                     AIRQFVRTNETMRFRLLFEGGDEPKQYIAEDEPFRIEYFDASEIGGADGVLKWGQAEAR
                     RPLPLYESPLFKFAVVRISEEESWFFAKVHHIISDGISMTILGNRITDIYLKLAKGETD
                     LEPVQSSFTEHIQSELEYENSKRFQKDKAYWNAQYEVIPEPVSLKASDTYQIQLNAARF
                     SKEISPVLYKKIQTYCKEHNISVLSLFLSILHIYMHRITGQKDVVLGTFMGNRTNAKEK
                     QMLGMFVSTIPMKASI"
     aSModule        20013..23138
                     /complete
                     /domains="nrpspksdomains_CE036_RS11825_Condensation_Starter
                     .1"
                     /domains="nrpspksdomains_CE036_RS11825_AMP-binding.1"
                     /domains="nrpspksdomains_CE036_RS11825_PCP.1"
                     /locus_tags="CE036_RS11825"
                     /monomer_pairings="Gln -> Gln"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       20016..20054
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0001"
                     /evalue="2.60E-03"
                     /label="C1_starter_004-017"
                     /locus_tag="CE036_RS11825"
                     /protein_end="18"
                     /protein_start="5"
                     /score="10.7"
                     /tool="antismash"
                     /translation="YPLTHAQRRIWYT"
     CDS_motif       20124..20195
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0002"
                     /evalue="3.10E-06"
                     /label="C2_starter_024-063"
                     /locus_tag="CE036_RS11825"
                     /protein_end="65"
                     /protein_start="41"
                     /score="19.8"
                     /tool="antismash"
                     /translation="IDSGLLTEAIRQFVRTNETMRFRL"
     CDS_motif       20409..20474
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0003"
                     /evalue="8.70E-09"
                     /label="C3_starter_134-155"
                     /locus_tag="CE036_RS11825"
                     /protein_end="158"
                     /protein_start="136"
                     /score="28.2"
                     /tool="antismash"
                     /translation="VHHIISDGISMTILGNRITDIY"
     CDS_motif       20805..20891
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0004"
                     /evalue="5.10E-11"
                     /label="C5_starter_265-294"
                     /locus_tag="CE036_RS11825"
                     /protein_end="297"
                     /protein_start="268"
                     /score="34.9"
                     /tool="antismash"
                     /translation="DVVLGTFMGNRTNAKEKQMLGMFVSTIPM"
     CDS_motif       20952..21059
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0005"
                     /evalue="5.00E-08"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="CE036_RS11825"
                     /protein_end="353"
                     /protein_start="317"
                     /score="25.5"
                     /tool="antismash"
                     /translation="QLKIIRHQKYPYNLLINDLRERQPHVSKLFAVSLEY"
     aSDomain        21396..22604
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CE036_RS11825_AMP-binding.1"
                     /evalue="4.80E-115"
                     /label="CE036_RS11825_AMP-binding.1"
                     /locus_tag="CE036_RS11825"
                     /protein_end="868"
                     /protein_start="465"
                     /score="376.4"
                     /specificity="substrate consensus: Gln"
                     /tool="antismash"
                     /translation="FEQKAADHPEKTAVVYEGQKLSYRELNEQSNRLARALRRRGIGPD
                     APAAIVMERSERVITAMLGVLKAGGAYVPIDPGFPEERIRFMLEDSKVKVVITDSGLTF
                     ETAETVRFSEALSESLENGHPSSEAGAGHLAYIIYTSGTTGRPKGVMIEHRQVHHLVRG
                     LQQAVGAYDQDDLKLALLAPFHFDASVQQIFTSLLLGQTLYIVPKKTVSDGRALSDYYR
                     RHQIDVTDGTPAHLQLLSAADDLSGVKLRHMLVGGEALSRVATERLLQLFAETAESVPD
                     VTNVYGPTETCVDASSFTMTNHADLQGDTAYVPIGRPIGNNRFYILDENGALLPDGVEG
                     ELYIAGDGVGRGYLNLPDMTADKFLEDPFVPGGFMYRTGDAVRWLPDGTVDFIGRKDDQ
                     VKIR"
     CDS_motif       21582..21623
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0006"
                     /evalue="1.20E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="CE036_RS11825"
                     /protein_end="541"
                     /protein_start="527"
                     /score="18.4"
                     /tool="antismash"
                     /translation="LGVLKAGGAYVPID"
     CDS_motif       21798..21857
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0007"
                     /evalue="7.90E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="CE036_RS11825"
                     /protein_end="619"
                     /protein_start="599"
                     /score="33.7"
                     /tool="antismash"
                     /translation="AYIIYTSGTTGRPKGVMIEH"
     CDS_motif       22251..22274
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0008"
                     /evalue="1.30E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="CE036_RS11825"
                     /protein_end="758"
                     /protein_start="750"
                     /score="5.6"
                     /tool="antismash"
                     /translation="YGPTETCV"
     CDS_motif       22398..22487
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0009"
                     /evalue="8.80E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="CE036_RS11825"
                     /protein_end="829"
                     /protein_start="799"
                     /score="46.8"
                     /tool="antismash"
                     /translation="PDGVEGELYIAGDGVGRGYLNLPDMTADKF"
     CDS_motif       22569..22634
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0010"
                     /evalue="9.50E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="CE036_RS11825"
                     /protein_end="878"
                     /protein_start="856"
                     /score="39.9"
                     /tool="antismash"
                     /translation="FIGRKDDQVKIRGYRIELGEIE"
     CDS_motif       22848..22871
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0011"
                     /evalue="1.40E+00"
                     /label="NRPS-A_a10"
                     /locus_tag="CE036_RS11825"
                     /protein_end="957"
                     /protein_start="949"
                     /score="2.6"
                     /tool="antismash"
                     /translation="GKVDRKAL"
     aSDomain        22932..23138
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CE036_RS11825_PCP.1"
                     /evalue="3.00E-26"
                     /label="CE036_RS11825_PCP.1"
                     /locus_tag="CE036_RS11825"
                     /protein_end="1046"
                     /protein_start="977"
                     /score="83.4"
                     /tool="antismash"
                     /translation="EEKMVGIWQEVLGTEQVGIHDQFFELGGHSLKAMAMLAKIYKAFG
                     VEVPLQVLFEKPTVAALSGFVSEA"
     aSDomain        23181..24038
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CE036_RS11825_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="2.80E-107"
                     /label="CE036_RS11825_Condensation_LCL.1"
                     /locus_tag="CE036_RS11825"
                     /protein_end="1346"
                     /protein_start="1060"
                     /score="350.1"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHLVSDG"
                     /tool="antismash"
                     /translation="DDYPLSLAQQRIYIVSQLEDAGVGYNMPAAAMLEGTLDVQRLEAA
                     FQKLIDRHEALRTSFTVVDGEPRQNIHQRVQFKIEKVKADGKPIEQMAKSFVRRFDLAK
                     APLMRAGLVRLADRRHVLLFDMHHLVSDGVSISIILNELAALYKGEELPEPNLHYKDYA
                     FWQRTQAQKGFQKEEAYWQSVFARELPVLQLITDEPRPSVQSFEGDRVSAVLPKDMKEK
                     LAVLAEQNGATLYMVMLAAYNMLLAKYSGQEDVIVGTPAAGRRHSDLEGIIGMFVNTLA
                     IRSKV"
     aSModule        23181..26255
                     /complete
                     /domains="nrpspksdomains_CE036_RS11825_Condensation_LCL.1"
                     /domains="nrpspksdomains_CE036_RS11825_AMP-binding.2"
                     /domains="nrpspksdomains_CE036_RS11825_PCP.2"
                     /locus_tags="CE036_RS11825"
                     /monomer_pairings="Leu -> Leu"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       23187..23219
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0012"
                     /evalue="1.00E+01"
                     /label="C1_starter_004-017"
                     /locus_tag="CE036_RS11825"
                     /protein_end="1073"
                     /protein_start="1062"
                     /score="0.3"
                     /tool="antismash"
                     /translation="YPLSLAQQRIY"
     CDS_motif       23253..23360
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0013"
                     /evalue="8.10E-18"
                     /label="C2_LCL_024-062"
                     /locus_tag="CE036_RS11825"
                     /protein_end="1120"
                     /protein_start="1084"
                     /score="56.8"
                     /tool="antismash"
                     /translation="YNMPAAAMLEGTLDVQRLEAAFQKLIDRHEALRTSF"
     CDS_motif       23556..23621
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0014"
                     /evalue="1.20E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="CE036_RS11825"
                     /protein_end="1207"
                     /protein_start="1185"
                     /score="27.5"
                     /tool="antismash"
                     /translation="MHHLVSDGVSISIILNELAALY"
     CDS_motif       23652..23684
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0015"
                     /evalue="1.50E-03"
                     /label="C4_LCL_164-176"
                     /locus_tag="CE036_RS11825"
                     /protein_end="1228"
                     /protein_start="1217"
                     /score="11.4"
                     /tool="antismash"
                     /translation="HYKDYAFWQRT"
     CDS_motif       23940..24029
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0016"
                     /evalue="9.80E-15"
                     /label="C5_LCL_267-296"
                     /locus_tag="CE036_RS11825"
                     /protein_end="1343"
                     /protein_start="1313"
                     /score="46.9"
                     /tool="antismash"
                     /translation="DVIVGTPAAGRRHSDLEGIIGMFVNTLAIR"
     CDS_motif       24078..24197
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0017"
                     /evalue="5.80E-19"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="CE036_RS11825"
                     /protein_end="1399"
                     /protein_start="1359"
                     /score="60.5"
                     /tool="antismash"
                     /translation="KKTVIDAFEHQEYPFERLAEKVGASRDLSRHPVFDTMFIL"
     aSDomain        24534..25727
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CE036_RS11825_AMP-binding.2"
                     /evalue="8.70E-111"
                     /label="CE036_RS11825_AMP-binding.2"
                     /locus_tag="CE036_RS11825"
                     /protein_end="1909"
                     /protein_start="1511"
                     /score="362.3"
                     /specificity="substrate consensus: Leu"
                     /tool="antismash"
                     /translation="FEEQAAERGGHPALQFEDKVWSYGELNRKANQLARRLRERGVQPG
                     TTAAILTARSAEMVIGILAVLKAGAAYVPIDPDHPEKRVQHFFEDSGAAVLLTQKAMKP
                     LAEAAEFGGDILFLEDEHLYLGDASDLRLPISPEAMANLTYTSGTTGTPKGNMVSHRNI
                     LRTVKNTNYLDVMTSDIVLSISNYVFDAFMFDVFGSLLNGAKLVIAPKDTILDMSRLAH
                     VLEKEKVTVLMITTALFNLLTDMRPDSLKGLRRVLFGGERASVDHVRRALNTVGKGRLL
                     HMYGPSESTVFTTYYPVNEVPDDAQAIPIGKPVSNTEVLILDSFGNVQPAGVAGELCVG
                     GDGLVRGYFNRPELTAEKFTEHPFKTGEKIYRTGDMARWLADGCLEFIGRIDHQVKIR"
     CDS_motif       24720..24761
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0018"
                     /evalue="5.80E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="CE036_RS11825"
                     /protein_end="1587"
                     /protein_start="1573"
                     /score="19.3"
                     /tool="antismash"
                     /translation="LAVLKAGAAYVPID"
     CDS_motif       24960..25013
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0019"
                     /evalue="8.90E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="CE036_RS11825"
                     /protein_end="1671"
                     /protein_start="1653"
                     /score="21.4"
                     /tool="antismash"
                     /translation="LTYTSGTTGTPKGNMVSH"
     CDS_motif       25383..25409
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0020"
                     /evalue="5.30E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="CE036_RS11825"
                     /protein_end="1803"
                     /protein_start="1794"
                     /score="3.9"
                     /tool="antismash"
                     /translation="YGPSESTVF"
     CDS_motif       25521..25610
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0021"
                     /evalue="7.90E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="CE036_RS11825"
                     /protein_end="1870"
                     /protein_start="1840"
                     /score="53.3"
                     /tool="antismash"
                     /translation="PAGVAGELCVGGDGLVRGYFNRPELTAEKF"
     CDS_motif       25692..25757
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0022"
                     /evalue="4.20E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="CE036_RS11825"
                     /protein_end="1919"
                     /protein_start="1897"
                     /score="37.9"
                     /tool="antismash"
                     /translation="FIGRIDHQVKIRGQRIELGEIE"
     CDS_motif       25965..25991
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0023"
                     /evalue="1.70E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="CE036_RS11825"
                     /protein_end="1997"
                     /protein_start="1988"
                     /score="5.0"
                     /tool="antismash"
                     /translation="GKVDRRALP"
     aSDomain        26049..26255
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CE036_RS11825_PCP.2"
                     /evalue="9.30E-30"
                     /label="CE036_RS11825_PCP.2"
                     /locus_tag="CE036_RS11825"
                     /protein_end="2085"
                     /protein_start="2016"
                     /score="94.7"
                     /tool="antismash"
                     /translation="EAQLADLWQEVLNVPKIGVHDNFFELGGHSLIGMTLIARIQQEMN
                     VDLQLKDLFQAPTIETLAQAAEKT"
     aSDomain        26298..27155
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CE036_RS11825_Condensation_LCL.2
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.00E-107"
                     /label="CE036_RS11825_Condensation_LCL.2"
                     /locus_tag="CE036_RS11825"
                     /protein_end="2385"
                     /protein_start="2099"
                     /score="351.6"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIISDG"
                     /tool="antismash"
                     /translation="ETYPVSSAQKRLYVLQQIEGAEKSYHMPAVLQLEGKLDLKRLESA
                     AQMLIKRHEAFRTTFEIKGGEPVQRIWEAAELTIDVIDADEQEAEKLIKEFIRPFDLTK
                     APLFRMSIIRFTGEKHLLLVDMHHIISDGASVSVLIDEMTKLYAGEALEPLRIQYKDFS
                     VWQQHLLTERHKVQEEYWLKELAGELPVLTLPADYPRPSIQTFEGSRLSFALKPELVQQ
                     LRKLAKETDSTLYMVLAASYSALLSKLSGQSEVIVGSPAAGRPHTDLSRIIGMFVNTLA
                     IRTRP"
     CDS_motif       26304..26339
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0024"
                     /evalue="3.60E+01"
                     /label="C1_starter_004-017"
                     /locus_tag="CE036_RS11825"
                     /protein_end="2113"
                     /protein_start="2101"
                     /score="-1.3"
                     /tool="antismash"
                     /translation="YPVSSAQKRLYV"
     CDS_motif       26367..26477
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0025"
                     /evalue="1.10E-15"
                     /label="C2_LCL_024-062"
                     /locus_tag="CE036_RS11825"
                     /protein_end="2159"
                     /protein_start="2122"
                     /score="50.0"
                     /tool="antismash"
                     /translation="SYHMPAVLQLEGKLDLKRLESAAQMLIKRHEAFRTTF"
     CDS_motif       26673..26738
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0026"
                     /evalue="1.40E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="CE036_RS11825"
                     /protein_end="2246"
                     /protein_start="2224"
                     /score="27.2"
                     /tool="antismash"
                     /translation="MHHIISDGASVSVLIDEMTKLY"
     CDS_motif       26769..26807
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0027"
                     /evalue="2.20E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="CE036_RS11825"
                     /protein_end="2269"
                     /protein_start="2256"
                     /score="13.9"
                     /tool="antismash"
                     /translation="QYKDFSVWQQHLL"
     CDS_motif       27057..27146
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0028"
                     /evalue="1.20E-12"
                     /label="C5_LCL_267-296"
                     /locus_tag="CE036_RS11825"
                     /protein_end="2382"
                     /protein_start="2352"
                     /score="40.2"
                     /tool="antismash"
                     /translation="EVIVGSPAAGRPHTDLSRIIGMFVNTLAIR"
     CDS_motif       27195..27314
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0029"
                     /evalue="8.00E-20"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="CE036_RS11825"
                     /protein_end="2438"
                     /protein_start="2398"
                     /score="63.3"
                     /tool="antismash"
                     /translation="KEMTLGAFEHQDYPFEELIEKLNIQRDMSRNPLFDAVFSM"
     CDS_motif       27840..27878
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0030"
                     /evalue="1.50E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="CE036_RS11825"
                     /protein_end="2626"
                     /protein_start="2613"
                     /score="18.1"
                     /tool="antismash"
                     /translation="AILKAGAAYVPID"
     CDS_motif       28080..28139
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE036_RS11825_0031"
                     /evalue="1.70E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="CE036_RS11825"
                     /protein_end="2713"
                     /protein_start="2693"
                     /score="32.7"
                     /tool="antismash"
                     /translation="AYLIYTSGTTGQPKGVMVEH"
ORIGIN
        1 aatcaaacct gatataaaaa ccccgatcaa aacgaacgga atcgcttcta ttaatatact
       61 gataaatatt gagttcagct gcagaaagga ttgtgaagcc acaaaaaaac ctccgcgcaa
      121 atgcatattt ttagtttcaa tctagcatta taacataaat tgaaaaagcg gttttgtgcg
      181 gcggggtcag ataatgggag gagcagaagt gacagaatca atacatataa aatccataca
      241 cagccttgaa ggggaatgtt atgataagaa tattcaaaaa atgaaaagaa gaggggaaag
      301 acaagatgca gcagccttat gatatgccgc tagaacagct ttatcagtat aaaccggaac
      361 ggacggcacc ggctgatttt gaagagttct ggaagggttc attggaggaa ttgtcaaata
      421 taaaagcgga gcctgagctt gaaccgcatg aatatccggc tgacggggta aaagtctact
      481 ggcttacata cagaagcacc gggggagcgc gaatcaaagg ctggtatgca gtacccgacc
      541 gccaagggcc gcatcctgcg atcgtcaaat atcacggcta taacgccagc tatgacggag
      601 acattcatga tattgtcaat tgggctcttc acggttatgc ggcattcggt atgctggtcc
      661 gcgggcagag cagcagtgaa gatacagaga cctctcaaca cggacatgta cccggctgga
      721 tgacaaaagg aatcctcgat ccgaaaacat attactacag aggggtctat ttagatgccg
      781 tacgagcagt cgaagtggtc agcggttttg ctgaagtcga tgaaaagcgg atcggagtga
      841 tcggggcaag ccaaggaggc gggctggctg tcgcggtttc ggcgctgtcc gatattccaa
      901 aagcagccgt gtccgaatac ccttatttaa gcaattttca acgagcgatc gatatagcga
      961 tcgaccagcc ttatctcgaa atcaactcct ttttcagaag aaacaccagc ccgaatattg
     1021 aacaggcggc catgcggacc ctgtcttatt ttgatatcat gaaccttgct caagcggtca
     1081 aagcgcccgt tctcatgtcg atcggactgg ttgacaccat cacaccgcca tccaccgtct
     1141 ttgcggctta caatcacttg aaaacggata aagaaataaa aatgtaccgc tattttggac
     1201 acgaatacat cccgccgttc caaaccgaaa agctggcgtt tttgagaaag cacctgaaat
     1261 gaataaaagt gaacacccgg tgaagccggg tttttttatg tcttgattta agaatatatc
     1321 gtattataag atataattag agagggtgat gaaaatgaat acagagaaaa tcatagaaat
     1381 gatgaatcag gactggacgg atatttacta ccatctgcac acaaagcatg atgatcattt
     1441 gtctcaccac gcggttagaa tgcttcagca tatcgaaaaa aaccgcttgg tgaccattgg
     1501 ccatttagca aaattattgg atgtctctca taatacggca tcagaacatg tgaaaagact
     1561 gatacaaaaa ggacttgtac agaaaaaccg ggacagcagc gatgaacgca aagtctacgt
     1621 cacgttaacg cctgaaggtg aagaagcagt gaaacggcat acgagacttc atccgaaaaa
     1681 actgcaaaag gtgctggagc aattaaatga ggaagaagtc gaaatgatta aaacagcatt
     1741 ttccttgttg agccgggagg caaaatcatg tttttaatag tgaaaatcgg ggtttctgca
     1801 atattgatcg ccattataac cgaaattgca cgaaaatcgc ctgaaatggg tggaatgatt
     1861 gcggcattgc ctcttgtcag tctgctgagt ttattttggc ttagtgtaca aggggaatct
     1921 ttaaagcatt taagccaatt cgcgaaaggc gtgctatggg ggtttcccgc cacggcggtt
     1981 ctccttttga tcgtggtttt gagtttaaaa gcatcatttc cggttgtcat ttctgttgtg
     2041 tttggagtat gcggatgggg cgggtgttta atgctgcaaa aggctctcat ccatgcgata
     2101 ttcgggtgaa ggggaatgga ataagaagcc gcttgtgctg ccgcacaagc ggctgaaacg
     2161 atcagggagc ggcatacccc cctgtatgag actgtcacgt ataaagcttg gagtaataaa
     2221 tcatcctcgc cggaaaagga acgtctctgt atggcccctc gggcgggatg gatgtcgaca
     2281 gaaatcggaa ataatggctc ccgagtattt ttaagtttat cggataagtc tggacggttt
     2341 caggagcgag ttcataggag aatgcttgag ctttagattg actgaccatg aacttttgat
     2401 attccccgtt ttcaaagcaa tataaatagc cctttaaacg atgcgcttcc tggttgacca
     2461 aagagatata cagatcttct cggccgtttt tttcaaccgg gtttcctgct ttgtcagaca
     2521 agtaaatcaa tcttgtttga gatgggctgc cgctgttcat ttgacagtta acaggttcaa
     2581 tgcaagcagg atgagtcgag agccggtcag aatgcggggc atgtgaaatc aattcaaaat
     2641 agtagggtgc tacatcgtcg gcatcccgat tccatttgca atcgtgctca gcctttgggt
     2701 cgaacatgaa ggactgggtg atgatataaa cgatgtgtct gcccgcagga acatgctgga
     2761 acctgatttt gatttccttg gacgaatgag cgggaacgat ggatggaaag gtttgcgagg
     2821 gccggtcatt tccttcaaag aaaacggata tatggatgcg gtcttcggca ttcgtatggt
     2881 tgcagcagac gtatgatgct tggaaatggc ctgatggatc ggtttgatag cttaatttgt
     2941 ttctgtcgat cgtataaagg tgatctgcgt gaaaataagt cgatctgagg atatggataa
     3001 taccgcctcc gtttcacagt atggaaagcc gccggagcac ccggcagctt cttgctattt
     3061 tttgatataa acctctgtcc gcttctccag gaaatcctgg agcaaagcga tcgccgagca
     3121 aacggcccag taaatcaagg caactaaaat atacatcgtc atatagtcga actcccgtcc
     3181 gcctacgatt tttgcctgtt gaaacaattc aggcacggtg atcatggcgg cgagggaaga
     3241 cgctttaacg agatcaagca ttacgtttgc aagaggcggg agtgcaattc taaccgattg
     3301 agggacaatc acgtggcaca tcgtctgcca gtaggaaaag ccgatcgatt ttgcagcgtc
     3361 ccactgccct ctgtcaacgg acgacagggc cgagcggata atctcggcaa tgtatgcggc
     3421 gctgttcatg ctgaagccga ttaaggcagc agtcaaagcc gtaaattgga ttccgatata
     3481 aggaaaacca aaataaagaa taaatagaat gacaaggatc ggaacgcctc tcataaacga
     3541 aatatagatt cttgccggcc aacgaagcaa agagatctcc gacatgcgcc caagcgcgat
     3601 gaaaaaaccg agaattaaac cggcaaacat gctcgcaaat gaaataaaaa gcgtattcca
     3661 tatgccttgc atcacataag gaaacgattt cgcagccaat tctgcattaa aaatatactc
     3721 ccattgaata gagcccaatt gacatccctc tatttattca catcgacatc gacaaagtcg
     3781 atatcctgct ttttcgaaac atcggcaccg ccgaaaaact ttttcgaaat ctttttgatt
     3841 gtgccgtcct tcagcatttc gtcaatcgtt ttgtcgaatt gtttttttag ttctgcgttt
     3901 ccttttttca tgatcatgcc ttgctgatgc ggatagtatt taagatcggg atgaatagtc
     3961 agatccagat caggcattgc ggcgagcgcg agtttttgaa ggtagtagtc gtttaagatg
     4021 acatcggttc ttccattcgc tacatccttt aaaaattggt catttgttgc gttgtcgtaa
     4081 atgacttcct cagctccgta ttggcgcgcg atatccatgt aaactgtcgt agctgcgcca
     4141 gcggctttct ttccctttaa atcttcaagc gtgtggatgc ctgatagatc ttttttgcgg
     4201 acgatagccg ttccgaatga atatttataa ggcgtagaga acaaaaactt ttctttgcgg
     4261 tcgtcggtca ttgtaatatc gttggcagca gcgtccactt gtccgctccc gaccgccgtc
     4321 agcatgccgt caaagcccat ttctttaaat tcgacatcca ggtcgagccg tttagccgct
     4381 tcacggatga cttccacttc gtagccggtc agcttgtctt tgccggaatc agtgtcatga
     4441 tatgaagtag gataaagggt tcccgaagtc gccacaacga tcttcccttt ttcctttatc
     4501 tcatcccagg ctgttttttg attttcagcc ttattttgag tagtgctgca tgcagctgtt
     4561 ataagagcga gcgctaacac cgttatcaac aatgtaatgc gcttatacgt atgcaattta
     4621 ttcacttaaa aaatcctcct attcctttag tcaagtaaac catagcactg aagtagggat
     4681 taggcaataa gataattagt attgggaaaa aataaaataa ttgatagtgc aacctgcttt
     4741 actttttaag gtgaaagatg gaatcataaa gatattggta aattgaaaca caaggaggat
     4801 aagaaaagat gaaaaatatt ttaatcatca acggacatga agcctatccc catgcaagag
     4861 gacagcttaa tcacactatt tttacagcga tggcggacaa gctgggtgaa aaatatgaag
     4921 taaaaaaaac agtggtggca gacggctatc aaatcccgga ggagcacgag aaattcaagt
     4981 gggctgatgc tgttatttat cagacgcctg tttactggtt cagtgttcct gctttattta
     5041 aaaaatatat tgatgaaatt tatgagtacg ggctttttta tcaagggtct gaagactacg
     5101 gcagaggcgg gctgtttaca gacaaaaagt atatgttttc aaccacatgg aacgcgccca
     5161 aggatgtatt ctccaaagag gggacatttt tcgaaggtaa aagtcttgat gaagcgctct
     5221 ttcatttgca caaaatgcag gaattcgtcg gcatgaagcc tttaaaaaca ttctctgtcc
     5281 atgatgtcat cagcaatccg caagtagatc aatatttagc tgatttggac gcccatttaa
     5341 aagaagtatt ttcgatttaa gtcaagaggt ttgtgctcag gcgcaaacct cttttttcgt
     5401 tatccgctaa gaaaacgtga tacagttgag taaaagcaaa gcagggggtg ctcgcatgtt
     5461 tttaaaaaag ctgactttac ttcgggaaaa agttccttct tatgcaaaat atcctttttc
     5521 aattcctgct attcaacatt taaaagaact gacgtttcaa aaaaacgtaa cattttttgt
     5581 gggggaaaac ggatcaggca aatcgacgct gcttgaagca atcgcagata aatgcgaatt
     5641 taacacggct ggcgggggaa gaaataatac atatgaagtg tacggttccg gttcggattt
     5701 gggagactat atcagattgt catggcttcc taaagtaaca aacggctttt ttctgcgcgc
     5761 cgaatctttt tatcattttg ctactcatat tgatgaagta gacatcaccg gttttcgagg
     5821 ctacggaggc agatctcttc acgagcaatc acacggtgaa tcttttttat cgcttttcaa
     5881 acatcgtttt aaagagaagg gaatctatct tctcgatgag cctgaagctg ctttgtcccc
     5941 ggcaagacag ctggcatttt tgaaaattct tcatgatttg acgaaatcaa accaagctca
     6001 gtttattatc gcctctcact cccccatttt attagggtat ccggaagccg acatcttcag
     6061 ttttgatggt gaacaaatca ctgaagtgaa ctatgaggat acggatcatt acaccttaac
     6121 caagtatttt cttcagcacc gggaaaagct tctggcggag ctgtttttag atgatgtttg
     6181 atctgaaacg cgtttcatag gatatgataa agtgcatccg gatcaaaata cgaaacagga
     6241 gttgagccat atgattcatc agcaattacg cccatttcca aaccatttcc tatggggatc
     6301 agcttcagca gcctatcaga tcgaaggagc ctggaaggaa gacggcaaag gcctctcggt
     6361 ttgggatgtg ttcacaaaga ttcccggcaa aacgtttaaa ggaagcaatg gagacattgc
     6421 ggtcgaccat taccaccgtt ttaaagaaga tgttgcttta atggccgaga tggggttaaa
     6481 agcataccgt ttttcagtca gctggccgag gatttttccc caaggcaggg gagaagtcaa
     6541 tgaagcgggc ttgagatttt acgatgactt gattaatgag ctccttgctc atgatattga
     6601 acccgttttg acgctttatc attgggatct tccccaggct ttaatggatg aatacggcgg
     6661 ctttgaatcc agaaggatta tagaggattt caatacgtat tgcgttacgc tctataagcg
     6721 gtatggggac agggtcaaat attgggtgtc tcttaacgag caaaattaca attttaatca
     6781 tgcctttatc acagcgatgc atcctccggg tgtgaaggac aggaaacgct tctatgaggc
     6841 taaccatatt gcatttctgg cgaatgcaaa ggcaatcgat tcttttcgcc ggtatgttcc
     6901 cgatggaaaa atcggaccga gttttgctta ttcgcctgca tatccgctct ccagccgttc
     6961 ggatgatatc ctcgctttcg aaaatgctga ggaatttaca aattattggt ggcttgatgt
     7021 gtattgccgg ggaacatatc cgggcattcc tttgaaatat ctgaaggaaa aaggctgggc
     7081 gccgacaatt gaggaggggg atatggagct tttagcaaaa ggaaaacctg atttcgtcgg
     7141 tgtgaattat tatcaaacca tcacatatga aatgaatcct ctagacggag tagcggaagg
     7201 aaagatgaat acgaccggcc aaaagggcag caaccaggaa acaggtatgc ccggtttata
     7261 caaaacaaag aggaatcctc atcttgagac atcgaattgg gattgggcca ttgacccgat
     7321 cggtctaaga atcgggcttc gcaggatttc cagcagctac gggcttccgc ttttcataac
     7381 ggaaaacggg cttggggaat tcgataaggt tgaaaatgac ggcacaattc atgatgatta
     7441 cagaattgcc tacttgcgtg cgcatcttga acagtgcaga caggctttaa acgacggagt
     7501 cgatttaatc ggctactgca gctggtcttt tacagattta ttgagctggc tgaacggcta
     7561 ccagaagaga tacggtttcg tttatattaa tcgtgatgaa gagaatgtaa aggacttgaa
     7621 gaggattaaa aaagacagct tttgctggta ccaaaatgtc attcagacaa acggggaaga
     7681 gctttaggag aagggcgccg gtgacaccgg cgcctttatt ctttgatcag gcctgtttaa
     7741 aatcgagaat ataggtgatc ttcgcagtgc tgcttttatc aggcataatc gtatagcatg
     7801 tcagctgata gacgccttgc gggatgtcgc atgacaattt cttggatagg acgcttgcaa
     7861 tttcgacccc gccatgaagc acgtcgaaag aaacggtgac gcgcctgtta aaggagggaa
     7921 cctgttcctg gacattcaaa cgaacttcta ctaatgatgc cgtattatcg agagcttcaa
     7981 acgagaccgc gtgttctccc gctgtgtagc ctcttttaat atcctcgtct gtccaatcca
     8041 taacgggcgg ctttccgcct ttttgataaa cggtaaactg atggtatgac atcgtcattt
     8101 cttctgcttc ccactttttg atcaaagaac gtacctccag tgttatttaa tcttgaaaag
     8161 tattttcgtg ccgtccggat aatcgcttac ctgattgccc acccaagatc ctgctccacg
     8221 gttatcagaa ggactgatat actcgacgga agcacctgtt ccgccttctt cgcacatggc
     8281 catcggccac tcgtcgcggt catagcccga tttggaagga acatctttta acgattcctt
     8341 tcggcgttcg tcggctccgt ccctgtcgat cgtacagatt ttagaatgcc ctttcttgat
     8401 ggcctttcga atgtgcgcgc ctgtttcagg atagcggtcc gacgggaaaa tcagcacttc
     8461 atcatagtct gagccgtttt gccggcctga aggctggtgt tctgaagtga aaaaatcgcc
     8521 ggatataatg ccgatgatca cgacggcgac ggcgagcaag gtgatcagca aagatttaat
     8581 tttgtccatt cgtgttgtcc tgctttctta taagttgaat cactcagccg cagcgggccg
     8641 gaagtaaata caactttatt atcgtaaaaa taatttgaga aataaagggg agattaatag
     8701 gtttttcctc ctgaaaagct gaattttagt ctatcatatc gccttttttt aaaattttgc
     8761 cggttcgttt agaaggtttt agaggttcaa aatttaaatt tctcatatgg aagaaaaact
     8821 ttcgagcccc ctttatcaag ctttcctgcg cgaatgatat gaaatacaag acagaaaagg
     8881 agctgactga gttgcttcgt aagctattga aggcacttca aaacggtaaa aaccgacgat
     8941 acagcagcag tgactacgga cggaaatcat acaaaaaata cagcagcagc gattataaaa
     9001 gaaaagggta cggtcatcac cattacaaaa gaaagcataa gaaatttttc ggcagcagct
     9061 aaatcgcgtg aaaacattga tgagatggct gtttgaccgc ccgctcaaaa aaggaaccgt
     9121 cttggagggg agatatcgaa tcaaccgtgt gctcgggatg ggcagctacg gtatcacata
     9181 tcttgccgaa gaacttggga gagctggttt ccgcgtcatc aagcagcaga gaaagacaaa
     9241 agcatggaca tcagccggcc ggaggtcttt caaccgcgag gctgaaattt tgcgggaatt
     9301 agatctgcct gtcgcgcccc gtatatatga ggtgcttcat gcggccggcg agcggtttat
     9361 cgtaatggaa tatatcgaag gaaaaacctt tgaagatttg ctcttttatg atggacatgt
     9421 ctttgatgaa cagcaaacga tcagcatatt gaaggaagtg cttcacagcg tttcatttct
     9481 tcacaggaga gggattattc accgcgattt gaggattccc aatttgattg tgagcggagg
     9541 aacgatccgc attatagatt tcggactagc atgccatctg actgaaagag aacgtgttga
     9601 tgaccggcac ccggaaaaaa ggctgatgcg tgctgtttcc gtcaaaagtg acttttatgc
     9661 gctgggacat ttcgcattgt ttctcctgta ctccgagttt actccgtccg gcgaggaaga
     9721 aaaaagctgg gaagaagaac tctgcctatc gtccgggttt acatccgttc tgaggaagat
     9781 gttgcaaatt gatcagccgt atgagcgtgc agaagatatt atcggcgact tgacttcctg
     9841 tacggcgaaa aagatgaagc agccgtttta acgacagccc agcgtgtcga caaaccctcg
     9901 cagtcgttgt caggcctgct aagtcggtct gacgaataga aggaggatcg ggaggctgac
     9961 gttctgaggg tcacgctgaa aggatgacaa aatcctaaaa ctaaaagtcg ttttgggatt
    10021 ttgtcaacgc gagaagatta atttttgtcc ccaatttcaa cttaaatcgt ttgctcttca
    10081 ctgcattccc ctttttgttt caccagtaaa tacatatcgg ttaagacgga gacgttttga
    10141 caagatgaac aaaaaacccc gttgtgaaaa cggggtttta aacaatttga aagcctaaag
    10201 ttcctctgtt ttttcggctt tttttgtttc atactgtttt tgtttatttg cgatgtagct
    10261 tctggcctct tgatgcatac gctgtttcag tttgtagact tcgctgtttt gatagatatg
    10321 tgaattgtag tttagcggag atgcattttt cccttttcct gttgcgtcga tcaaggcgga
    10381 gtagtcggac tggatcattt gctgaatttg ctcagaggcc gagtattctc ttttgagcag
    10441 cccgtcaaga tcctcgacag ctttaatcgt gtcttttctg ttttggtttg cagcatcgag
    10501 ctgctgtttg atttcatcgg aagagaatgg ctgtagcgat attaaatcat caatctgtcc
    10561 taaaatattc gacagttctt gttgctgtgc agagaccatg ttttgagagt gaatgtggac
    10621 atttgcaagc tcctgttcaa gaaattgaac atcaacgaat gtgtcctctg aaagtccggc
    10681 attttcggcc gcagcagata caccattcag aaactgaatc tgcatatcag ctaaatccag
    10741 ccagccgtct acgatccctg attggtctct gtaaaacgct ttaatggcat cagcgccttt
    10801 tccttggaac tcatcaagtt ctgtgacgct gtttaacgat tgttttaagc tgacgagctg
    10861 ttctctcaag tttttatatt catcagatct ttgcttcata gctgataata gggtttccgc
    10921 ttcgtagact ttcattggaa atctgccctt cctgcgactt atatagtaca gagtgtacca
    10981 ctttgtcaca ggggattggg caataaatcc tgaatatcca tgaaaatgaa tctttgtgat
    11041 caaatttgta agctctttag gctttttgtc gtgataggag acttttgatt taatagttaa
    11101 ttagtccctt ttatggcgga gttgtgtcgt cggactgaag aaaagcagac aactaaaaat
    11161 gtgaaatact gtgaacaaca caattgaaaa tgtgatgata tggtatctta aaattaaata
    11221 ttaaataaaa aagactcgga atattgtaat taaacataat tgactacttt ctcatgcttg
    11281 attagtataa tagtaaaata tttttaaaaa aggatatttt taaaaggggg ggatcgggat
    11341 tgaatgaaga aggttaccgg cttggaattg atattggagg aacttttacc gatcttacat
    11401 tgttaaacca ggcggacggg agcatgaccg cagttaaaac gccgaccgtt cccgaagatc
    11461 cggcccaagg gatcatcaac ggtttggctc tcttgaagac ccagggtgtt cacccttcag
    11521 aaattcatca cttcgtacac ggcatgacaa tcggtttgaa cacattatta caacgcaaag
    11581 gggctgatat tgctttattc gtaaccgaag gtttccgtga tattctttcg cttcaacgcc
    11641 tccggcttcc gataccgtac gattttagat cgagaatgcc ggagcccctt attccccgga
    11701 aaaacgtgtt tcccattcaa gaaagaatgc tttatgacgg ctctgaaaag ctgccgctcc
    11761 ataaggaaga gatcgatgag gcggttggac aagttttaag aaaaggatta aaaggaatcg
    11821 ttgtttcttt tttgcacagc tatcggaatc cgcttcatga acgccaggct gcagaacgga
    11881 tcagacaaat agcacctgag cttgaggttg caacgtctgc ggagctttgg ccgcaaatga
    11941 gggaatacga acggacggtt atggccgtcg caaacctata catcaaaccg aatgtccatc
    12001 actactttcg aacgctgaaa gagaggctcg ccctggaagg aatttcagcg cagccgttta
    12061 tcacccagtc taacggagga ctgatggaca ttgaatcggc tgccgaggca cctgtcaaaa
    12121 cgcttttttc cggaccggca gcaggggtca tcggtgccat cagaacggcg gaaaccgccg
    12181 gagaggcgaa tatcatcaca tttgatgtcg gaggaactag cgcggatatt tcgattgttg
    12241 aagaagggga gccgactttt acacagtcaa atcaaatctc tggatttccg attacgattc
    12301 cgtctgtagc gatgtattcg atcggtgctg gcggagggtc ggtggcatgg attgacagcg
    12361 gcggtctctt gaaagtagga ccggagtcag ttggatctga tccggggccg gcttgttacg
    12421 gaaaaggaac aaaggccgca cttacagatg cgtttcttat atgtcattat ttaaatccaa
    12481 accggtttgc atcaggaaat atgaaactgt accgggaaag atccgaaaaa gcgctcctcc
    12541 cggttgccga atatttaggc acagatgtgg agcaggccgc ggatcagatg attcaggttg
    12601 cgcttgccaa tatgtacacg gaactaagca atgttatgga gcaaaacggg tttgacccgc
    12661 gtgaattcag cctcatggcc tttggaggcg caggaccggt cactgctaat tttttagctg
    12721 aggaaattca ggccaaaaat gtgctgatcc cgccgcatcc gggaaccttg tccgctttgg
    12781 gcgcactgac ggcggatttt atttatgatg ctgtatgttc aagacaggtg ctgcttgaac
    12841 aaataaaaac ggtcgagtta aaagcggagt ttgtaaggct gcaagagcaa gcggaaacat
    12901 ggctgcggaa acagcaggcg gagatgctgc cggaaacctc tcttctttac ttgcttgatg
    12961 cccgttataa aggtcaggca tacgaaattg agctccttgt ttcaccggaa tgcctggaag
    13021 gcaaaagcac gagtgaaatc gcggactcct ttcacctctt acatgaaaag caatatggac
    13081 acagcgatga gaaagcaagc attgagttga tgaatatacg cgtccgcatc ataggcaaga
    13141 caccgaagcc gccaggcgga aaaggaggcc gaagtgagct gcccgaggct gaaccggtca
    13201 gccaaagaaa gatcatcata aaaggcggta catatcaaac cgctgtatac caacgttcag
    13261 atttaaggtg cggccagaga ataaatgggc cggccattgt tgagcaagat gatacaacga
    13321 cgctgatttt gccaaattgg agcggaaaaa ctgatcatgc cggaaatttg atcattgaac
    13381 ggaaggagag ctgaccatgc gcacagatcc tgcccggctg gaaatgatga gaagctactt
    13441 taacgcgata gccgcgggaa tgggacacgt tattgaacgg acgtccttta ccacatttgt
    13501 aaaagagtca gctgatttcg ctactgcgct tgcgacgccg gaaggggaat ttttcgttta
    13561 tccgaaaacg gtcggcgtca cgattttttt aggcctttca ttaaaacgga tcatcgaaga
    13621 aagcggccca tttgaaccgg gagacattat cctcacaaat gatccctata caacggacgg
    13681 attggcgacc cacttgcctg atatacatgt agtgaagccg attttcatgg agggcgaggt
    13741 catcagttac gcgtggtgtt ttgtccattg cagcgatgtc ggcggccttg ttccggcaag
    13801 catttcgccg acagcgacag acatccatca ggaaggcctg aggataccgc cggtgagaat
    13861 ttacaaagcg ggaagagaaa atcgcgatat attgaatgtg ctgcgggcaa acagcagggt
    13921 tcccgactta aatgaagggg atattcatgc gatggtggcc gcggtcaata cggcggagaa
    13981 ccgattgaca gagatggtcg gcaagtttgg aaaagaagcg gtccaacaag gaatggatga
    14041 tttgctcgaa caagcagcga tgagagccgg ccgggttatc agcgggattc cggaaggcac
    14101 atacagtttt tcagactatc ttgatgacga tatgatttct gacgttccga tccgcttggc
    14161 tgttacggca aacgtctcgg gaggggaaat cacattggac ttttcagact gtgatcccca
    14221 ggtgaaaacc gcatttaacc ttgtcactaa tggaagcaaa cattcatttc tatttcaggg
    14281 cctgatcaac tttatcataa gtgaagaccc gtatattccg gttaacgggg gactgacaag
    14341 gccgatcaaa gtcatcgctc cgaaaggtac actggttcat ccggaatatc cagcggccgt
    14401 cggaattcgt cattcgatta cgatgagact ttataatgcc gtactgggcg ctttggccaa
    14461 ggcgcttccg aaagctgtgc ctgcagcagg cgccggtcag tcagcgattg tcgtactgtc
    14521 ggttcccggc gaatcaacgg gcggccggaa gatgtctgtg gtcgaaccga tgggaggcgg
    14581 aggaggcggc cagcatgaca tggacggagc agacggtatt gaccatgcat ccggattttt
    14641 aaaaaatacg ccgattgaaa gccttgaaca gcacattgac atccatgtcc gccgctatga
    14701 gctgattaaa gataccgccg gagccggttt tcacaggggc ggccatgcaa tcgggctgga
    14761 gtttgaagcg acggcgccag aatcaattgt gaccgcaaga gggatggaga gaatgcgatt
    14821 tcatccgtgg gggctcgccg ggggaacggc aggagcgctc ggacgggtgc gtctttatcc
    14881 ggagcagcct caggagaaaa cgatttcgaa gatcgacgtt ctaaagctca acaaagggga
    14941 tgttatcagc attcattcgc ctggcggcgg aggctgggga gatccataca gccgggaagc
    15001 tgaatcgatt ttgagggaag ttgaatcggg cttgctgagc ccggaagcgg cataccatca
    15061 atacggcgtg gctgtaaaag aaaacgatgc aggctcattc attattgatc tggaagaaac
    15121 agctgaaatc agaaaaaaga aagcaggcga acctcggaaa cattgggatt tcgggcttgc
    15181 tagagaagaa tacgaacggt gctggacaga ggaagccagc agcacattgg cccggattct
    15241 gcgacagctt ccggctcatc aaagatcaca tgttaaacat ctagtccacc gttatttttc
    15301 aaaagagcat aacggttcga tcagcaaagg cgatgttgcg gccgctgtgg aaaaactggc
    15361 tggcaaaaat aacacgggaa tggtgagatg acaatgaaaa gtaaaatttc tgctttattt
    15421 attctgtctc ttgtagcggt gctccttctt tcgggctgcg gcggaaaagg tagtcaggaa
    15481 agcaaacaat cagatacagt cgttatcggc gtctatggag gcgattggga aaaacatatt
    15541 aagcctagcc tcgaatcttt tgaaaaagaa acagggctga aggtcaaagt cgtcgcaggg
    15601 acagactctg agtggtttac aaagctcaaa gctgcaaatg gcagaaatgc tccgtatgat
    15661 ctcttaatcc tgcagccgga tacgattcac agggcacagt cggcgggatt actggcgccg
    15721 attgatcagg aaaaggttcc gaatgtccgc gatctgtatc attccgttca gaaacgcttc
    15781 actgatgatg gaaagcagta tgcggccggt ttcagtatgg ggcagctcgg aattgtctac
    15841 cgaaaggacc ttgtaccgca ggagcctaaa cgctggacgg atctttggaa cagcagctat
    15901 aaaggtcatg tggccatatc atcgccggct tattcggcgg gacttcagtt ttttgtagga
    15961 ttaatcaatg cccagggcgg cctggagtca aatgggaaag acgtggataa agcgttcaac
    16021 agtttgacgg atttaaagaa caacataaca gcctatcccg ataatccggg ctcgatacaa
    16081 acacttttgg aacgcgggga tgcatgggtt gtcccgtttt gggacggacg cgctttttct
    16141 ttgcaggacg ccggtcttga cctgggattt gcatatcccg aggaaggtgc cgtcgcagca
    16201 gttgcaagct gggctttgat gaaaggaagc cctaatcagg ataacgcata caagctgtta
    16261 aatcacctgc tcagtccaaa agtgcaagga gattttgccg atagaacatt ttacggcatg
    16321 gccaataaaa aagtgaaata cagcgataaa ttaaaaggaa agattaaagt aggggaggac
    16381 tattacagga atttaaaatg ggttgactat gaagtcgcgg caaaagatct aggcgattgg
    16441 acaaatcgct ggaatcaagt acttggcgga aaataggtga caaacatgag cgcaattcag
    16501 attcagcatg tcagccggca tttcggaaac accatcgcat tggaagacgt acagcttgaa
    16561 gtcaaagaag gggaattttt ctctctcctc ggtccgagcg gctgcggaaa gtcaacgctc
    16621 cttcatatca ttgccgggtt ccttgaaccg acgtcagggt ttgtatatat aggaggaaga
    16681 gatgtaactg atttgccgcc atacgaccga catattggaa tggtttttca ggattatgct
    16741 ttattcccgc atctcagcgt atttgacaat gttgcatacg gattgaaagt tcgaaaatgg
    16801 ccccgccgca agattgaaga acgggtgatg gaaagcctcg cccttgtcag gcttgaagcg
    16861 tttgctaatc gcatgccccg tcagctgagc gggggccagc agcagcgggt ggcgattgcc
    16921 cgggcattgg cgattcagcc gtctgtgcta ttgctagacg agccgctgag caacttggat
    16981 gcgaaacttc gaaaagaaat gcagacggag ctgcgcagca tccaaaagcg cgtcggtatt
    17041 acaacgattt tagtgacgca cgatcaggag gaggctttaa gcttatcaga cagaattgga
    17101 atcctcggct gcggcaggct tcagcagctc ggcactccgt tggacgtgta ccgcacgcct
    17161 gctaatcaat ttgtcgccga atttatcgga caggtcaatt tgctgaaagc gcgtgcgtcg
    17221 aagatacagc cttcatcagg cgtttatggc tatgaagcgg tcgattttga aatatatgaa
    17281 ggtgttccgc tgacttttga aatcagccgg aatctcttaa aaaaatcctc tgtattgttc
    17341 atggtgcggc ccgagagaat ctcagtctct ttcgagaaac agaagaacag gctgattgaa
    17401 atgcctgcaa cgataacgga agtcagttat gccgggcatg ctctcaggct gaaagccgct
    17461 gttttcaaag gagaatggat cattcaggcg cccgatcctc aatttccaag attgccgaag
    17521 gcgggggatc aagtgtatct ttctttggat ccggacgatt ttgttccgct cgatgtaaag
    17581 gaggatgcag atgggtgctc ttgaacaaaa acggttttat tgggttttgc ttgttcccgt
    17641 ccttttattt ctcggcgttt ttctcgtgtt gccgcttgtt ctgctgctgt tattaagttt
    17701 cagagacgtg gacgctatga tgaatacgct cgatacgtac agtttttctc aatatgtcga
    17761 agtgttctct tcggacattt atttgaaaac catcggtata acgctttgga cggcgttgaa
    17821 gaccactgta ttatgccttg tgatggcgta tccggcagca tatttactcg ttaaggcgcc
    17881 gaccggcagg ctgcgggctt tgttttatat attgcttgtt tctcctttac tgaccagtgt
    17941 tgtcattcgg acgttttcct ggattgtgct gctttcgcaa aacgggatcg tcaatgaggc
    18001 gcttatcagc ttgaagctga ttgaaaagcc cctgccgctt ttatggaata tgaacgccgt
    18061 catcatcgca tatgtccagg ttatgctgcc gtttgctgtg ctgtcgcttg ccggttcttt
    18121 aagcgaaatg aaaccggatc ttaaatttgc ttcgatgagc cttggagcgg ggaggcttcg
    18181 gacatttttt ttcgtgacct tgccaatgac ggttccagga ttgctgacag gagcaatgat
    18241 cgtgttttcg ctttcggccg gaagctatat tacgcctctt ctcgtcggcg gaaggatgca
    18301 gccgctgctg ccgttatcaa tctatcagca ggtcatgcaa gtctttcatc ttcctcttgc
    18361 agcagctatg tcgattactt tattagccgt tgtcagcgtg gttattggaa tccttggctt
    18421 tttccaaaag cgttgggagg cgagaataaa tgggtagaca attgcgccgt ttgtctgggg
    18481 gaaagtggat tgatgtgtgc gtttgggcgg cgggtttatt ggtatacctt tttttggcgc
    18541 tgcctgtatt tgtgattata ctgtcggctt tcagcccgga cgaatatccg aagttcccgc
    18601 catccggcgt ctcgctgcgc tggtttgccg gagttttcag cagcagcggc tggatggaat
    18661 cgatttgggt gagcggtatg ctgcttctcg ttgtaacgcc tcttgcggtg atcctcggaa
    18721 cagttgcagc ttatgcattg gcgcggctga actttcctgg aaaacagggc attcaggctt
    18781 ttattttatc gccgttgatg attcctcaaa tcgcattagg cgtgtcattt ctctatttat
    18841 tgacaatgct tggggtaaac ggcacatttg ccggcctggc cgccgggcat atgctgatca
    18901 gccttccgta tgtcttacgg acggtcggcg tcagcatggc gaacgtggat ccgaagcttg
    18961 aactggcatc catgaatctt ggcgcaggtc catggtatac tttttttcat gttaccttgc
    19021 cgctcattaa accgggaatc attgcgggag ccgtttttgc cgctgtgacg tcattcgggg
    19081 aagtatcaat cagtctgttt gtttcttcac ctgctgtcac gcctgtaccg gtgcgcacgt
    19141 tcagctatat tgaccagacg tttgatccga gtgttaatgc gatttcggtt atttttatca
    19201 cagtttcagt gatcgcgctg atcatcatcg agcggacgat cgggctttca aaaaccgtgt
    19261 agcaggcgaa actcagcctg cttttttgta tggaacaccg aaagtatttc aagataccgt
    19321 ttaggaggag acagttcagt gattttccgt tctgcttcaa tgttttcgca agctgtttgt
    19381 cttttctcgt atcagtttaa acggctgggt aaaagaaacg ttttatttga atgaacattg
    19441 taaaagaaaa cgcctaagcc ttaacggatt ttcatgattt attcatgaag ttaaggctgt
    19501 ttttttaata ttttaatata ttctttatct aggatttgga attttttgcg gaattaagcg
    19561 gtttttttcg ttttcccgca tatttttttg tcgatttcgg tatcacgcat taacattcat
    19621 ggataacatt cggcatcccg catgaaactt ttcacctatt tttcggtgaa aaaaacaaaa
    19681 ttttcattta aagtgaactg tgagcagaaa atgaatttat atcaataaaa gcagataaag
    19741 gcaaacctgc ggaaacgcag ggacgcaaag ccatggccta aggtactgac ggtgctacgg
    19801 ttgacaggtt gccgaataaa cagggagttc gcccgttttt attcgggtgg actcttttct
    19861 tttttatttc caaaataatg ttttattgga aatgacaaat ctgtgacagc gtttttcgct
    19921 catcgcaata ccgcaacatt gcattgcggc ttggctgttc gcatcgtcat acatagcaaa
    19981 agataaagga ggaataaaaa atgggaaaca catgttaccc gctgacacat gctcaaagga
    20041 gaatttggta cactgaaaag ttctatcccg gcacaagtgt ttcaaatttg agcggctttg
    20101 gaaaattaaa atctgcctcc ggaatcgatt ccgggttatt gactgaagcc attcgccagt
    20161 ttgtccgtac aaatgaaacc atgcgattca gactgttgtt tgaaggaggg gatgagccga
    20221 agcaatatat agcggaagac gaacctttcc ggattgaata tttcgacgct tcagaaatcg
    20281 gaggagcgga cggcgttctt aaatggggac aagctgaggc gcgtcgaccc ctgcctttgt
    20341 atgaaagtcc gctgtttaaa tttgccgtcg ttcgcattag tgaggaagaa agctggtttt
    20401 ttgcaaaagt tcatcatatc atttccgacg gtatttcgat gacgatcttg ggcaaccgca
    20461 ttacagacat ttatttgaag cttgctaaag gggaaaccga cctcgaacct gttcagtcat
    20521 catttacgga acatattcag agtgagttgg agtatgaaaa ttcgaagcgg ttccagaagg
    20581 ataaagcata ttggaacgca caatatgaag tgattccgga gcccgtatcg ttaaaggcga
    20641 gcgatacgta tcagatccaa ttgaatgcag cccgcttttc aaaagagatt tcccctgtcc
    20701 tgtataaaaa aattcaaacg tattgtaagg aacacaacat aagtgtgctc tccctgttct
    20761 tatccatttt gcacatttat atgcaccgga taaccggaca aaaagacgtc gttctcggaa
    20821 catttatggg taaccggaca aatgcaaaag aaaaacagat gctcgggatg ttcgtatcga
    20881 cgattccaat gaaagcctcc attgatgtac accaggactt tagtgcattt gtgcaggaaa
    20941 gaatgaaaga tcagcttaag atcattcggc atcaaaagta tccgtacaat ctgctgatta
    21001 atgatttgcg ggaaagacag ccgcatgtca gcaaattgtt cgccgtctca ctggaatatc
    21061 aagttatgca atggcagagg aaagaaacgt tgtcatttct tactgagccg attttcagtg
    21121 gcagtgaagt aaacgatatt tccattcacg tgaaagagag atgggatacc gggacgcttg
    21181 cgattgattt tgattacagg gaggagcttt tcacctgtga agaaatggcc gttttatatg
    21241 aacggctgat gacgctgctt gaagatgcct tgttgtttcc gcaaaaaaca atcgctgaac
    21301 tggagattgt tcccgcattt gaaaaagagc ggctgttaaa gcgtgcatca agccaaacca
    21361 tcgcatatga caagaacatg accctgcacg gtttattcga acaaaaagca gccgatcatc
    21421 ccgaaaaaac cgccgttgta tatgaaggac aaaaactttc gtaccgtgag ctgaatgaac
    21481 aatcgaatcg tctggcaagg gcgcttcgaa gaagaggcat cgggcctgac gctccggctg
    21541 cgatagtgat ggagcggtca gagcgggtta ttacggcgat gctgggcgtt ttgaaagccg
    21601 gcggagctta tgtaccgatc gatcccggat ttccggaaga aagaattcgc tttatgctgg
    21661 aggattcaaa ggtcaaagtg gttatcacag acagcgggct gacttttgaa acggccgaaa
    21721 ctgtgcggtt cagcgaagcg ctttctgaat cgctggaaaa cggtcacccg tcttcagagg
    21781 caggcgccgg gcaccttgca tatatcattt atacttccgg gacaacgggc cgtccaaaag
    21841 gcgtcatgat tgaacacagg caggtccacc accttgtaag agggcttcag caggccgttg
    21901 gtgcatatga tcaggatgat ttgaagctgg cacttctggc tccgtttcat tttgacgctt
    21961 ccgttcagca gatttttacg tctctattgc ttggccaaac gttgtacatc gtaccgaaaa
    22021 agacggtttc cgacggacgc gctttatcgg attattaccg ccgccatcaa atcgatgtga
    22081 cagacggtac gccggctcat ttgcagcttt tgtctgctgc cgatgatctt tcaggtgtca
    22141 aactgaggca tatgcttgtt ggaggagagg cattatcaag ggtcgcaacg gaaaggctgc
    22201 ttcaattatt tgcagaaaca gctgaatccg tgcctgatgt aacgaatgtt tacggcccga
    22261 ctgaaacttg tgtggatgct tcttctttta cgatgacaaa ccacgcagat cttcaaggcg
    22321 atacggccta tgtcccgatc ggcagaccga ttggaaacaa ccgtttttat attttggatg
    22381 aaaacggtgc actccttcct gatggtgtcg aaggggaatt gtatattgca ggagacggag
    22441 tcggccgagg ctatttgaac ttacctgaca tgaccgcaga caagttcttg gaagacccgt
    22501 ttgtccccgg aggtttcatg tatcgaacag gggatgcagt acgttggctt cctgacggta
    22561 cggttgattt catcggccga aaagacgatc aagtgaaaat ccgcggctac cggatcgagc
    22621 ttggcgagat agagtcggtg ctgcaaggag cccctgctgt cggaaaagca gttgtcctcg
    22681 cgcggcccga aaccggcggc agccttgagg tttgcgctta tgtcgtgcca aaacaaagcg
    22741 gggaaattca ccttcagggg ctgagggagc atttatccaa gcatctgcct gactatatga
    22801 taccttccca ctttgtcgag cttgatgaaa taccgctgac gggaagcggc aaagtcgacc
    22861 ggaaagcgct gcttcgccat gaagtctctg tcagcgggac tgcagagtat gcggcaccga
    22921 gaaatgaata tgaagaaaaa atggtgggta tatggcagga agtgctcgga actgaacaag
    22981 tcggaatcca cgaccagttt tttgaactgg gcggccattc tctcaaagcg atggccatgc
    23041 tggcaaaaat ttacaaagct ttcggtgtcg aggttccgtt gcaagtcctg ttcgaaaaac
    23101 cgacagtggc ggcgttaagc ggctttgttt ctgaagcgga gaaagacgga ttcacggtta
    23161 ttgaacctgc gccggaaagt gacgattatc ctctctcatt ggcgcagcag cgaatttata
    23221 tcgtcagcca gctggaggat gccggagtcg gctacaatat gccggccgcg gcgatgcttg
    23281 agggcaccct tgatgttcag cgccttgaag ctgcttttca aaaactgatt gataggcatg
    23341 aggcgctgcg cacttcgttt acagttgtcg atggcgagcc gagacagaac attcatcaaa
    23401 gggttcagtt caagattgag aaggttaaag cagatgggaa gccgatcgaa caaatggcga
    23461 aatcttttgt ccgccgcttt gatctcgcca aagctccgct gatgagagca ggtctcgtcc
    23521 gtctcgcaga ccgcagacat gtgctgttgt tcgatatgca tcatcttgtg tctgacggcg
    23581 tatcgatttc gatcatattg aatgagctgg ccgcactgta taaaggggaa gaactgccgg
    23641 agccgaattt gcattacaaa gattatgctt tctggcaaag gacgcaggca caaaaaggtt
    23701 ttcaaaaaga agaggcttat tggcaaagcg tgttcgcccg cgagcttccc gtactgcagc
    23761 tgataacgga tgagccgagg ccgtctgttc aaagctttga aggagacagg gtatccgcag
    23821 tcctgccaaa agacatgaaa gaaaaattag ccgtgctggc agagcaaaac ggcgcgacat
    23881 tgtatatggt catgctggcc gcatacaaca tgctgctagc aaagtactcc gggcaggaag
    23941 atgtgatcgt cggaacgccg gcggccggcc gcagacattc cgatctggaa ggaatcatcg
    24001 gcatgtttgt caatacgctg gcgatccgtt caaaagtgga gtcgggcaga acgttcagag
    24061 acttcctgca tgatgtaaag aaaacggtaa tcgacgcttt tgagcatcag gaatatccgt
    24121 ttgagcggct tgcggaaaag gttggtgcat cgcgcgattt aagccgtcat cccgtctttg
    24181 acacgatgtt tattttgcaa aatgcatggg aagacattcc gatgctcggc gatttgcacc
    24241 tctcgattta tgaaacgaac ttcaatattg caaagttcga cctaacgctg caggcgaaag
    24301 aagagcaggg agaattgatt ctcgatttgg attacagtac gaagctgttt aaaaaagata
    24361 cggcagaaag gatgctgaaa gcatatttgc accttctgga gggcatgacg gctgatccgc
    24421 tgcgcagaat cggcgagtac agccttttga cagaagagga aacgaatcgt cagctcgtcg
    24481 cgttcaaccc cgcggcaagc gattatccga gggagaaaac gatcgttcag ctatttgagg
    24541 aacaggcggc ggaaagaggc ggacatcccg ccctgcaatt tgaagacaaa gtatggtcat
    24601 acggtgagct caatcggaaa gcgaaccaat tggcgaggcg cctccgcgaa agaggtgtgc
    24661 agcccggcac gacggcagcc attctcaccg ccaggtcggc tgaaatggtc atcggcattc
    24721 tcgctgtgct gaaagccggc gctgcttatg tgccgatcga tccggatcat cctgaaaaac
    24781 gtgtgcaaca tttcttcgag gacagcggag cggcggttct tttaacgcaa aaggcgatga
    24841 agccgctcgc tgaggcggct gaatttggcg gcgacattct atttcttgag gatgaacacc
    24901 tttatctggg agatgcgtct gatttgcgcc ttccgatttc accggaagca atggccaatc
    24961 taacgtatac atccggaacg actgggacgc ctaagggcaa tatggtttct caccggaata
    25021 tattgcgtac ggtaaaaaac acaaattact tggatgtgat gacatccgat atcgttcttt
    25081 caatttcaaa ttacgtgttt gatgccttta tgtttgatgt gttcggttca ttgctgaacg
    25141 gcgccaagct ggtgatagct ccaaaagaca cgattcttga tatgagccgg ctcgcacatg
    25201 tacttgaaaa agaaaaggtt accgtcttaa tgatcacgac cgcattattc aatctgctga
    25261 cagacatgcg gccggacagt ttgaagggac tccgcagggt tctgttcggc ggcgaacgtg
    25321 catctgtcga tcatgtcaga agagctctga acacagttgg caaaggacgg ctgcttcata
    25381 tgtacggccc gtctgagagc actgtcttta caacctatta tccagtcaac gaagtgccgg
    25441 acgatgcgca ggctataccg atcggaaagc ctgtcagcaa tacggaggtt ctgattcttg
    25501 attcattcgg caatgtacag ccggcagggg ttgcgggaga attgtgcgtc ggcggagacg
    25561 gccttgtccg cggctatttt aaccgcccgg aactgacggc tgaaaagttt acggaacatc
    25621 cgttcaaaac cggtgagaag atttaccgga cgggcgatat ggcgagatgg cttgccgacg
    25681 gatgtctcga atttatcgga cggattgatc atcaggtcaa aattcgcgga cagaggatcg
    25741 agctgggcga aatcgagcac catctcctca cacatgaaat ggttcaggaa gccgctgttc
    25801 ttgctgttga caccgggaag agagatcaaa tgatctgtgc ttactttacg gccgatcagg
    25861 agctttctag tgaagagctt cgccgatatg cggcagaagg tctgccgggc tacatgatcc
    25921 cgtccgtgtt tatgcagctg caggagcttc cgctcacagg caatggaaag gtcgacagaa
    25981 gggcgctgcc tgagccggat gtcacgcagg ccgcgcaaaa ggaatatacg gcgccaagga
    26041 gccgaacaga agcacagctt gccgatcttt ggcaggaggt gctcaatgta ccgaaaatcg
    26101 gtgtgcatga caatttcttt gaacttggcg gacactcttt aatcggaatg acgctcattg
    26161 cccgtatcca gcaagagatg aatgttgatc tgcagctgaa agatttgttc caggcgccga
    26221 caatcgaaac cctggcacag gctgcggaaa aaactgagaa aaaatcagcc atttatattg
    26281 aagcggcgcc ggatcaggaa acgtaccccg tatcttcggc gcaaaaacgg ctgtacgtcc
    26341 tacagcagat cgaaggcgct gagaaaagct atcacatgcc ggccgttctc cagcttgaag
    26401 ggaagcttga tttgaagcgc ctcgagtctg ccgcgcaaat gctgatcaag cgccatgaag
    26461 cattccgcac gacatttgaa atcaagggcg gcgaacctgt tcagcggatt tgggaagctg
    26521 cggaattgac cattgatgtc atcgatgcag atgaacaaga agcggaaaag ctgattaaag
    26581 aattcatcag gccgtttgat ttaacaaaag ccccgttatt tagaatgagc atcatacgtt
    26641 tcacgggaga aaaacatctt ttgcttgtgg atatgcatca tatcatttca gacggcgctt
    26701 ctgtcagcgt cctgatcgat gaaatgacaa agctttatgc gggagaggcg cttgaaccgc
    26761 tgaggattca gtataaagac ttttctgtat ggcagcagca tctgctgaca gaacggcaca
    26821 aagtgcagga ggaatactgg ctcaaggagc tggccggcga gctgcctgtt ttgacgcttc
    26881 cggcagacta tccgcgtcct tctattcaaa cgtttgaagg aagccgtctc agctttgcgc
    26941 tgaaaccgga gcttgtccag cagctgagaa aactggccaa ggaaacggac agcactttat
    27001 acatggtgct cgctgcctca tacagcgcgc ttttatccaa actgagcgga cagagcgagg
    27061 tcattgtcgg ctctccggct gccgggcggc cgcatactga tttgagccgg atcatcggca
    27121 tgtttgtcaa tacgcttgca ataagaacgc gtcctgaagg agacaagccg ttttctgcat
    27181 tccttgagga agtgaaagaa atgacgctcg gcgcgtttga gcatcaagat tacccgtttg
    27241 aagaactcat cgagaagctg aacatccagc gcgacatgag ccgaaaccca ttgtttgatg
    27301 ccgtcttttc aatgcgaaat gccgatttga aggacttgtc aatggaaggg atcacactca
    27361 agccgtatga ttttgcccat cagaccgcga agtttgacct gacgctgaca gcggcggaag
    27421 aggacggact tctcgttttt gaaatggaat acaatacagc tctctttaag catgaatcga
    27481 tcgagcgctg gcgcggatac ttgcttaacc tgctcgaagc ggttgccgaa aacccggatg
    27541 cccgcctttc agagctttcg cttctggatg aagcggaaaa acggcggatc gtccaaaatt
    27601 ggaatgagac gagactggct gtgctggagg acaaaacggt ccatgagctg ttcgaagcgc
    27661 aagttctccg cacgcctgac catggggcag cggtgtacaa cggcgtgaag tggacgtaca
    27721 aagagctgaa cgcgcgggcg aaccgcctgg ctcggctgct gatcgaaaaa ggggtccgcc
    27781 ctgaacagcg gatcgggatc atggtcaagc cttcgcttga aatggccgcc ggcgtgatcg
    27841 cgattttgaa agcgggagcg gcctatgtgc cgatcgatcc cggctatccg gccgagcgga
    27901 tcggatacgt gctaagagac agtggcgcag agctgctttt gacgcaaagc ggattaacgg
    27961 tgccggacac atttaccgga gacgtgatcg atttgaatag agaaggctcc attctggacg
    28021 gcgagcttta tccagaggat gacatgaatc caaacgcgca agctcagtca gacaacctgg
    28081 cctacctgat ctacacatcg ggcacgacag gccagccgaa aggcgtcatg gtcgaacacc
    28141 ggtcgcttgt gaatttgtgt tattggcat
//
