LOCUS       NZ_NKBC01000002        21935 bp    DNA     linear   CON 17-MAR-2024
DEFINITION  Bacillus paralicheniformis strain 9-1 9-1_R1_(paired)_contig_2,
            whole genome shotgun sequence.
ACCESSION   NZ_NKBC01000002
VERSION     NZ_NKBC01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus paralicheniformis
  ORGANISM  Bacillus paralicheniformis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 580262)
  AUTHORS   Cui,Y.
  TITLE     Improper usage of probiotics constitutes a potential risk of public
            health
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 580262)
  AUTHORS   Cui,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JUN-2017) Beijing Advanced Innovation Center for Food
            Nutrition and Human Health, College of Veterinary Medicine, China
            Agricultural University, Yuanmingyuan West Road, Beijing 100193,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 9.5.3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 20x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009935535.1-RS_2024_03_17
            Annotation Date                   :: 03/17/2024 02:24:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,539
            CDSs (total)                      :: 4,461
            Genes (coding)                    :: 4,361
            CDSs (with protein)               :: 4,361
            Genes (RNA)                       :: 78
            rRNAs                             :: 4, 1 (5S, 16S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 68
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 100
            CDSs (without protein)            :: 100
            Pseudo Genes (ambiguous residues) :: 0 of 100
            Pseudo Genes (frameshifted)       :: 49 of 100
            Pseudo Genes (incomplete)         :: 64 of 100
            Pseudo Genes (internal stop)      :: 15 of 100
            Pseudo Genes (multiple problems)  :: 21 of 100
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:47:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 133320
            Orig. end                         :: 155255
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            NKBC01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21935
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="1"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..21935
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21935
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11935](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11935)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            287..394
                     /locus_tag="CE036_RS01190"
     CDS             287..394
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388844.1"
                     /locus_tag="CE036_RS01190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YhdX family protein"
                     /protein_id="WP_003180159.1"
                     /transl_table=11
                     /translation="MGKGRIKVEERIKIETDAEMFKATLLDQTQSQKKK"
     gene            577..1653
                     /locus_tag="CE036_RS01195"
     CDS             577..1653
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003180161.1"
                     /locus_tag="CE036_RS01195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="WP_023856529.1"
                     /transl_table=11
                     /translation="MFEKYMTMDFAVDIGISIGILLLFFAFRKIFTKYLFNLILKLTNK
                     TKTDFFNQVVLAFEKPARWFFAILGIYLAIIYSPFFDGHMAIVHKLYRVSVILVIVSGL
                     YNLTAASSVLFDKINKRLELDMDDILAPFLSKILRFIIVALGISVIAGEFNYDVNGFVA
                     GLGLGGFAFALAAKDTVGNFFGGIVIIMEKPFTIGDWIETNIVTGSVEDISFRSTKVRT
                     AGEALVTVPNSVLANEAIMNWTKMRKRQVTFTLEIDPSTPREKVERCVERFKEMLKSHE
                     GVNPDVIMVNFDVLKDTHLSIFFNYYTNTTVWAENLDVRQDVNYRILDIMKEEQVDFVS
                     PGHSLFELKKMKDQQGDA"
     gene            1683..2432
                     /locus_tag="CE036_RS01200"
     CDS             1683..2432
                     /EC_number="2.3.1.286"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003180163.1"
                     /locus_tag="CE036_RS01200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD-dependent protein deacylase"
                     /protein_id="WP_043054254.1"
                     /transl_table=11
                     /translation="MEEKALRFVEMIENAERITVLTGAGMSTESGIPDFRSAGGIWTED
                     LSRMEAMSRDYYERYPKLFWPKFKELFQMKMTGTYQPNDGHLYLADLEKSGKDVKVFTQ
                     NIDGLHLKAGSRHVYELHGSIQTAACPKCGVRYGLDHILQEEVPRCHRVNGKGRECGFI
                     LKTDVVLFGDAVQHFDTLFEVLNESDLLLVIGTSLEVAPVRFVPEEAHLIPGLKKAMIN
                     LDKTPYDHLFDIVIHQKIAEFVRKLNC"
     gene            complement(2472..2966)
                     /locus_tag="CE036_RS01205"
     CDS             complement(2472..2966)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003180165.1"
                     /locus_tag="CE036_RS01205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_025811792.1"
                     /transl_table=11
                     /translation="MKIEELHSTAEYTNQLAELLIRVVDDGASIGFLPPLDEQLAEAYW
                     KTAVTPDSVLWIAKQNGRIAGSVQLHLCTKQNGRHRAEICKLMTDPAFRRQGVARSLME
                     KAIDRAKQEGRSLLVLDTREKDPSNLLYASLGFAEAGRIPAYAESADGSFDTSVFYYKK
                     L"
     gene            complement(3101..4012)
                     /locus_tag="CE036_RS01210"
     CDS             complement(3101..4012)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003180166.1"
                     /locus_tag="CE036_RS01210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_020450755.1"
                     /transl_table=11
                     /translation="MRQVSKKTAPSVAYLLTKAACFFVLCLILLYVWDLSQSSAATEKR
                     ELTVSENSQMRHEGDSVPLKKATQGELLDHLSTKQQIEKRKQEKEKQKAAAEKKQEKSK
                     EKTVYLTFDDGPSAVSQRLLQILSEHDAKATFFMLEPNMKLHKEAVLNMKQQGHALGLH
                     GVTHDQKQFYKGANSPHLEMKQAQKTLKSITGVETHLIRTPYGSKPSLTEAQKKVLKKN
                     GFIYWDWNIDSLDWKYRSQKFVPEVMNQLNMLEKRQTKQPIVILMHDIPSTVQSLPLLL
                     TNLKNMGYSFATLDESMTPVHE"
     misc_feature    complement(4091..4109)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 23.17"
                     /tool="antismash"
     misc_feature    4153..4166
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.97"
                     /tool="antismash"
     gene            4310..5161
                     /gene="dat"
                     /locus_tag="CE036_RS01215"
     CDS             4310..5161
                     /EC_number="2.6.1.21"
                     /GO_function="GO:0047810 - D-alanine:2-oxoglutarate
                     aminotransferase activity [Evidence IEA]"
                     /GO_process="GO:0019480 - L-alanine oxidation to pyruvate
                     via D-alanine [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_4 (42-271). E-value: 2.4e-47.
                     Score: 153.6. Matches aSDomain:
                     nrpspksdomains_CE036_RS01215_Aminotran_4.1"
                     /codon_start=1
                     /gene="dat"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020450756.1"
                     /locus_tag="CE036_RS01215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="D-amino-acid transaminase"
                     /protein_id="WP_143261150.1"
                     /transl_table=11
                     /translation="MKVLFNGRLMERSECAVDIEDRGYQFGDGVYEVIRIYNGILFTLD
                     EHIARLYKSAAEIGIDLSFSEAELKSQLKELVDINQRRDGGLYLQVTRGKAPRKHQYGA
                     GLTPQVTAYTFPIQKPEKEQQNGVSAITADDMRWLRCDIKSLNLLYNVMIKQKAQEASA
                     FEAILIRDGLVTEGTSSNVYVVKQNVIYTHPVTTLILNGITRMKVLQLCEENGLNYEEK
                     AVTKDELLNADEVFITSTTAEVIPVTSIDGQTIGSGAPGPLTKNVQTALQNSILSETAK
                     TV"
     aSDomain        4436..5122
                     /aSDomain="Aminotran_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CE036_RS01215_Aminotran_4.1"
                     /evalue="2.40E-47"
                     /label="CE036_RS01215_Aminotran_4.1"
                     /locus_tag="CE036_RS01215"
                     /protein_end="271"
                     /protein_start="42"
                     /score="153.6"
                     /tool="antismash"
                     /translation="TLDEHIARLYKSAAEIGIDLSFSEAELKSQLKELVDINQRRDGGL
                     YLQVTRGKAPRKHQYGAGLTPQVTAYTFPIQKPEKEQQNGVSAITADDMRWLRCDIKSL
                     NLLYNVMIKQKAQEASAFEAILIRDGLVTEGTSSNVYVVKQNVIYTHPVTTLILNGITR
                     MKVLQLCEENGLNYEEKAVTKDELLNADEVFITSTTAEVIPVTSIDGQTIGSGAPGPLT
                     KNVQTAL"
     gene            complement(5202..6560)
                     /gene="nhaC"
                     /locus_tag="CE036_RS01220"
     CDS             complement(5202..6560)
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="nhaC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009328967.1"
                     /locus_tag="CE036_RS01220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="WP_020450757.1"
                     /transl_table=11
                     /translation="MSNEKRLSFSISALLFLAILFIIFTCLFIFKAEAHIPLLICVGFL
                     AAVGAVKGHSWKDLESGIVSGIRNGVQPIIVLCLIGILIGVWEYSGAIPTVTVYALNLI
                     EPQHLLLTALFSCLVISSLVGSSFTTVSTIGVALIGVAAAAGVPLTWAAGAVICGACFG
                     DKMSPMSDTTNFAAGVGELPIFKHIRHMAGTTIPALLITILLFFFMGRSLTAAPASTEN
                     IHAIINGIEGTVNISVWALLSPLLVIVLAVRRTPVIPSLATGIVSAGILAALIQPDASI
                     SSFLSAMQNGPVFSADTEAVEKILNRGGLQSMMGSVSLIIIAFALGGLMEKIGLITSLL
                     EGVIKGIHTKGRLVFSTVSSSIGMNLATGEQYLSILIPGQSFKKLYDKLGIDRKHLSRS
                     LEDGGTLINPMIPWGVSGAFMSSALGVPVIEYLPFVFFLYLSPLFSILFGFRK"
     gene            6798..7778
                     /locus_tag="CE036_RS01225"
     CDS             6798..7778
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009328966.1"
                     /locus_tag="CE036_RS01225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aldose 1-epimerase"
                     /protein_id="WP_143261151.1"
                     /transl_table=11
                     /translation="MSYTVQKSRFLDEEAIWLENDDLEAVLVPGWGSNLISLKWKPSGL
                     KLLKAPETKEEYDANPFLFGIPVLFPPNRIDHGRFTYAGRTYELPINEKPLENHLHGFL
                     YDKKWTVEKVEATEERIIVQTKLDSEDHPDIKAIFPHSFSITITYTLEGQHLKIDASAV
                     NRGQDPMPIGLGYHTSFRYPLNEAGDKERCLFTLPASKRWTLTDRMLPTGEYRVTEEFK
                     AGKMAAGERLDDILAAEQDQEGNSAAVIADSLAGIRVRYQCDGHFKHWVVFNGTSDQDD
                     LLCIEPYTWMTNAPNLNLPKNVTGFRDLGPQEELTMRSKIEVGGI"
     gene            complement(7795..8028)
                     /locus_tag="CE036_RS01230"
     CDS             complement(7795..8028)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF027626.4"
                     /locus_tag="CE036_RS01230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4944 domain-containing protein"
                     /protein_id="WP_237612047.1"
                     /transl_table=11
                     /translation="MVTKFGDEIVLNSQVETPMKDYAGGELPGGGSKEQSVSFLEELEE
                     AEFAGRKVTVQLDWREGKQASHTAFTLDKSSW"
     misc_feature    8122..8138
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 23.0"
                     /tool="antismash"
     gene            8197..8907
                     /locus_tag="CE036_RS01235"
     CDS             8197..8907
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CE036_RS01235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_143261152.1"
                     /transl_table=11
                     /translation="MKNIFVSLLVLCLVSISAFIGIEDAFAAEELQEEAYSESIKSADD
                     LQYDVNKNLTQEEITSRFNKINTKYDVGQAFSEQDAEFIKFYADSQLETPSELNDGISI
                     SAIQWYPGQTASKSFNTSKSSNGVKVKFSGKVYGTIGIVNHSYRGKLSAKITSGTSKVK
                     KALKVRVTHSAYGLVGKKSIGIVYNSGKSSTGTKSKVSMDNTVKYSALAVVYTYTNAYV
                     SVTTKTGSFNKYAF"
     gene            complement(9447..9923)
                     /locus_tag="CE036_RS01245"
     CDS             complement(9447..9923)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003180175.1"
                     /locus_tag="CE036_RS01245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4944 domain-containing protein"
                     /protein_id="WP_023856536.1"
                     /transl_table=11
                     /translation="MKQEYKRPLLFIASLFTAFCTVYFGGRLIGFYMTEYPKWNGQSAD
                     GNWEAVIKKIEGRTLFGGDLYWTGDRGELDDIYLEKLVVKFGDEIVLNSQVETPMKDYA
                     GGEFPGGGSKEQSVSFLEELEEAEFAGRKITVQLDWREGKQASHTAFTLDKSSW"
     gene            complement(10001..11935)
                     /locus_tag="CE036_RS01250"
     CDS             complement(10001..11935)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03882"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003180177.1"
                     /locus_tag="CE036_RS01250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_143261153.1"
                     /sec_met_domain="TIGR03882 (E-value: 2.5e-48, bitscore:
                     159.5, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 8.9e-135, bitscore:
                     444.5, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 7.6e-85, bitscore: 280.7,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRCILVIGEGLMAEDASQQLSAEYNIIRRSDFENSIPEETAFAL
                     VLHDAWRPLLYREAEKVLRAAGIPWLRGFASFGEGVIGPLVNPSASGCSQCADMRRYIS
                     GPDSRETLELEQKSNGISRDPWVSKTGCRQMVSLICTEVDNIMNGGCGRLIKNLYIVNL
                     KTLESSLHAFIPEPTCPICGSLPEDGAESARISLRPSLKTNPDSFRVRNTDDLKQTLAK
                     DYLDHRTGIFNAKIYDAILPFADMIVNMPLWTGNEGVGGRSHSYEDSELTAILEGLERY
                     SGIEPRGKRTIVHDTYENVKDRALNPAKVGLHQAEQYMHPDFPFQPFHPARPLRWVWGY
                     SFLQKRPILIPESLAYYSLGREDSFVYETSNGCALGGSLEEAIFHAILEAAERDSFLLA
                     WYARLPLRQLDLGSSEDSELRLMTERVRSVAGYDLHVFNSTMEYGIPSVWAIAKNRKRE
                     GLNLICSAGAHPDPVKAVKSALHELAGMMLKHDRKFESERSKYHQMLRNPALVQEMEDH
                     SFMYGLPEAEERLRFLLNQSRPLQTFDDAFKKRKKHLDLTEDLCDLLEAFRSLNLEVIV
                     VDQTSPVIKRNGLYCVKVLIPGLIPMTFGQRFIRLEGLERIFTVPKELGFAEEPLTPEQ
                     LNLHPHPFP"
     gene            complement(11935..13791)
                     /locus_tag="CE036_RS01255"
     CDS             complement(11935..13791)
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03693"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Heterocycloanthracin_C_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiopeptide_F_RRE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006636651.1"
                     /locus_tag="CE036_RS01255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="putative thiazole-containing bacteriocin
                     maturation protein"
                     /protein_id="WP_095289921.1"
                     /sec_met_domain="TIGR03693 (E-value: 0.0, bitscore: 1116.0,
                     seeds: 2, tool: rule-based-clusters)"
                     /sec_met_domain="Heterocycloanthracin_C_RRE (E-value:
                     9.3e-53, bitscore: 171.5, seeds: 5, tool:
                     rule-based-clusters)"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 4.5e-14,
                     bitscore: 47.5, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHLTASARLKVNQDTWFLPDPNGGAYFRNNSGSFRIKGSSIAQW
                     IEKLLPMFNGEHSLEDLTKGLQAPYRKRVYEIGEMLYKNGFVRDVSRDHPHKLESSVLQ
                     TFEAQIEFIESFADSGAYRFQLSRQTKILAIGAGSFLTKLVRSLIDSGFSRIRAIVTDA
                     SGHALDELAEISGQTESGLEIGCAETQHWREAVRSADWVLYVSDRGFTDELRDLQTFCL
                     EENKGFIPGICLKQVGLAGPVFHQQGDGCLKDAWRRLHRSALHEERALRTFPSAGKDML
                     ANVIVFELMKATAEIAPLSKKNQVYLIDLATLEGGWHMFLPHPDFACGKDLPELICDLE
                     AKLSERPGREAESRLFQCFSELTSPVTGIFHLWEEKHLRQLPLAQCFVQTADPLSSGPA
                     ELLPETVSVGLTHQEARREAGLAGIEMYASRLNRSYPSNGELFAIAAGETLAEGVLRGL
                     EKCLEHRLRERIKSGKETISLVQLGGMEDRHTAFYLKALTVLYGKPEIGLGKNIQGFPV
                     AWAGIRGRWYGSSGLNITFALRKALERALTDKDPVKGADVLLESSDLKLATPVSADLQQ
                     TLLSALKNNCGLQLYVYELPAEPFFKEKLAGIYCVQLRKEES"
     aSDomain        complement(13492..13791)
                     /aSDomain="Heterocycloanthracin_C_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing C protein in a
                     heterocycloanthracin LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CE036_RS01255_Heterocycloanthracin_C_
                     RRE.1"
                     /evalue="4.30E-54"
                     /identifier="RREFam011.1"
                     /label="CE036_RS01255"
                     /locus_tag="CE036_RS01255"
                     /protein_end="100"
                     /protein_start="0"
                     /score="171.5"
                     /tool="antismash"
                     /translation="MTHLTASARLKVNQDTWFLPDPNGGAYFRNNSGSFRIKGSSIAQW
                     IEKLLPMFNGEHSLEDLTKGLQAPYRKRVYEIGEMLYKNGFVRDVSRDHPHKLES"
     aSDomain        complement(13525..13770)
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CE036_RS01255_Thiopeptide_F_RRE.1"
                     /evalue="2.10E-15"
                     /identifier="RREFam004.1"
                     /label="CE036_RS01255"
                     /locus_tag="CE036_RS01255"
                     /protein_end="89"
                     /protein_start="7"
                     /score="47.5"
                     /tool="antismash"
                     /translation="ARLKVNQDTWFLPDPNGGAYFRNNSGSFRIKGSSIAQWIEKLLPM
                     FNGEHSLEDLTKGLQAPYRKRVYEIGEMLYKNGFVRD"
     misc_feature    13900..13913
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.97"
                     /tool="antismash"
     misc_feature    complement(13901..13914)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.02"
                     /tool="antismash"
     misc_feature    13902..13915
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.21"
                     /tool="antismash"
     misc_feature    complement(13905..13921)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 22.69"
                     /tool="antismash"
     misc_feature    14350..14367
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 18.69"
                     /tool="antismash"
     gene            complement(14898..15398)
                     /locus_tag="CE036_RS01265"
     CDS             complement(14898..15398)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017695384.1"
                     /locus_tag="CE036_RS01265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="universal stress protein"
                     /protein_id="WP_023856540.1"
                     /transl_table=11
                     /translation="MFKADRIIVAFDGKEESKKALKKAIDLSKRLGSQLTVAHVHEPRQ
                     VRTEAATERPAAGAPYLYSGFPAAPRVPHDSDLAGEPMIYEDSAEEAIAAAKIILSENQ
                     YDAEIEVLEGDPANAVLQHAENIGADLVITGTRDQNRLKKLLFGSVSDKISTKSEIPVL
                     IVK"
     gene            15920..17674
                     /locus_tag="CE036_RS01270"
     CDS             15920..17674
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388852.1"
                     /locus_tag="CE036_RS01270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_101560656.1"
                     /transl_table=11
                     /translation="MFSVLWKLGWFFKASWRRYTIAVVLLIIVNVLEMFPPKLLGNAID
                     DMQAGTFSKAGMLGYIGLFLALGAVVYILSYYWMYQLFGGANLVEKILRSKLMGHLLKM
                     TPSFYEKNRTGDLMARATNDLKAISMTAGFGILTLVDSTMYMLTILLTMGFLISWKLTL
                     ASIIPLPLMAAAISIYGKKIHERFTEAQDAFGALNDRVLESVSGVRVIRAYVQEKNDVS
                     RFNSMTADVYKKNMKVALIDSLFEPTVKFLVGISYLIGLGYGAYLVFRSQLTLGELVSF
                     NVYLGMLIWPMFAIGELINVMQRGNASLDRVNETLAYEPDVREPAEPEAAEPGDIVFDG
                     VAFTYPSSASENLADISFTVLEGQTVGVVGKTGSGKTTLVKQLLRQYPKGKGTITISGV
                     PIDRLPLDQLRSWIGYVPQDHVLFSKSVKDNILFGGRLAEERDLYDVISAAHLKKDIEM
                     LSDGLETMVGEKGVALSGGQKQRISIARAMIAEPHILILDDSLSAVDAKTEAAIIENIR
                     SRRKGKTTFITSHRMSAVEHADFILVMENGRIVERGTHQELIGRKGWYFEQYEAQQLPS
                     GEEGGTVA"
     gene            17671..19689
                     /locus_tag="CE036_RS01275"
     CDS             17671..19689
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) ABC_efflux"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003180189.1"
                     /locus_tag="CE036_RS01275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_143261154.1"
                     /transl_table=11
                     /translation="MTTGKRLFQYALLYKKILIWALVMLTIAVTAELTGPMIAKKMIDD
                     HILGIEKTWYETTEKTKYTVSYKGKEYIREDRTDSSAEKLQEVHIFQVGMNYYFVEEPV
                     SFDGERTVSGEDLRMTSGDRTETYKADRLSLSEVYAFYEPEIGGLISLVSIYFGLLVFS
                     IFFHYGQFYLLQMSANRIIQKMRQDVFANIQRLPIRYFDNLPAGKIVARVTNDTEAIRD
                     LYVTVLSTFVTNIIYMAGIFAALFFLDVRLAGVCLLILPLIVIWAAVYRKFASGYNHKL
                     RSINSEINAKMNESIQGMPIIQAFRRGQDTKEEFEQLNESHFHYQNKMLKLNSLMSHNL
                     VNILRNVMFTALIWYFGGAALNAEGMISIGVLYAFVDYLNRLFQPITGIVNQFAKLELA
                     RVSSERVFRLLDEPGVDVKEPGSERARGRVVFEDVSFRYHDGEDVLKNISFEAQQGETV
                     ALVGHTGSGKSSILNVLFRFYDIEKGDVKIDGRSIYDMSRQEIRKQMGIVLQDPYLFSG
                     TIASNVSLDNADLTRDQIEAALKQVGALEMLARLPKGLDEPVIEKGSTLSSGERQLISF
                     ARALAYDPAILILDEATAHIDTETEAVIQKALDVVKQGRTTFIIAHRLSTIKNADQILV
                     LEKGRIIERGNHEELMKQKGQYYQMYELQKGKGTLTG"
     gene            complement(19709..20335)
                     /locus_tag="CE036_RS01280"
     CDS             complement(19709..20335)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009328963.1"
                     /locus_tag="CE036_RS01280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)H-binding protein"
                     /protein_id="WP_230368433.1"
                     /transl_table=11
                     /translation="MLKIALFGGTGRVGQAFLNFVEEDGRYSVYALVRRTEGARIPDKC
                     CQALAGNARNQHDVESLIKDSDIVVSCLNTDGDDTLTVSIEHMINAMNAHRIKRLITIG
                     TAGILNARQNQDLYRFETNESKRRSARAAQEHARVYERLRESELDWTIVCPTYLPDGPA
                     LKTYRFEQDVLPDGGKEISTGDTAHFLFKQLESDQFVKARVGLAY"
     gene            complement(20356..20499)
                     /locus_tag="CE036_RS22380"
     CDS             complement(20356..20499)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003180193.1"
                     /locus_tag="CE036_RS22380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_023856545.1"
                     /transl_table=11
                     /translation="MQLMLSINWELIQFVGISLLNEYVSNVHPYHGTFCFRGAFSSGRS
                     DV"
     misc_feature    complement(20668..20683)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 21.62"
                     /tool="antismash"
     gene            complement(20670..20873)
                     /locus_tag="CE036_RS01285"
     CDS             complement(20670..20873)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390835.1"
                     /locus_tag="CE036_RS01285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta-type small acid-soluble spore protein"
                     /protein_id="WP_020450770.1"
                     /transl_table=11
                     /translation="MANQNSSNQLVVPGAAQAIEQMKFEIASEFGVNLGADTTSRANGS
                     VGGEITKRLVSQAQASMGGQQF"
     gene            21107..21331
                     /locus_tag="CE036_RS01290"
     CDS             21107..21331
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003180197.1"
                     /locus_tag="CE036_RS01290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_020450771.1"
                     /transl_table=11
                     /translation="MMCPVCNGILVQTRHCPKCGGEMADAGRATDFFGPYSPYMEFDSF
                     KQTQTVCVHLYTCQDCTYEETVEIETTEA"
ORIGIN
        1 ataaaatcag ccccgagctc caccgctttt tcaaaagcgg caaacgtatt ttcaggggcg
       61 taagccgagg ctccgcgatg tgcgataata tgcaagcatg tcagctcctc ttgataaaat
      121 ctttccatca caaggatacc cgattttgac gatgcaagta aatcatttga ctgaagcgga
      181 caaagggcag ggagaagaga caagcgacaa atttcggcaa aatggtacaa aaggatcatt
      241 tactaaagat tctgatattt tataatggac aaaaggaggc gagatgatgg gtaaagggag
      301 aattaaagtg gaagaacgga ttaagatcga aaccgatgct gaaatgttta aagcgactct
      361 ccttgatcaa acacagtctc agaagaagaa atagcggtgt tggcccgaat cacgttgtct
      421 ctggaacaat aaaatatgat gatcatcagg ctgccgaagt gttcggcagc cttttatgcg
      481 tgtcgacggt tatttttggt gcacaataaa gtgagaaatt tttttctcgt tttagtataa
      541 ttaaagcttg atgagtgaaa taagggagag aaagcaatgt tcgaaaagta tatgacaatg
      601 gatttcgctg tcgatatcgg aatcagcatc ggtatccttc ttttattttt cgcgtttcga
      661 aaaatattta cgaagtactt gttcaactta atactgaaat tgacgaataa gacgaaaaca
      721 gactttttca atcaggtggt gctggccttt gaaaagccgg cccggtggtt ttttgcgata
      781 ctcggtattt atctggccat catatattcc ccgttttttg atgggcatat ggcgatcgtt
      841 cataaactgt acagagtgtc cgtgattttg gttattgtaa gcgggctata caacttaacg
      901 gcggcttcgt cggttttatt cgataaaatc aataagcggc ttgagcttga tatggatgat
      961 attcttgcgc cgtttttgtc caagattctc cgctttatca ttgtagcact cggaatcagc
     1021 gtcatcgccg gagagttcaa ttatgatgtc aacggatttg ttgccggact cgggctcggc
     1081 ggcttcgctt ttgctcttgc ggcaaaagac actgtcggca actttttcgg cggaattgtc
     1141 attattatgg agaagccctt tacaatcggc gattggattg aaacaaatat cgtcaccgga
     1201 tctgttgaag atatatcgtt cagaagcacg aaagtccgca cggccggaga agctctcgtg
     1261 accgtcccca actcggtgct ggctaacgaa gcgatcatga actggacgaa aatgcgaaag
     1321 cgtcaggtca cctttacgct cgaaatcgat ccgtccaccc cgcgcgagaa agtcgaacga
     1381 tgtgtggagc gtttcaaaga aatgctcaag tcgcacgaag gggtcaaccc ggatgtcatt
     1441 atggtcaatt ttgatgtcct gaaggatacg catttaagca tcttcttcaa ttactatacc
     1501 aatacgacgg tctgggccga aaacttggac gtcagacagg atgtcaacta ccgcattctt
     1561 gatattatga aagaggagca ggttgatttt gtttctccgg gtcacagcct ctttgagttg
     1621 aagaaaatga aagatcagca aggagatgct taggtaacgc ttttggaagg gagacaagcc
     1681 aaatggagga aaaagccctg agatttgtgg agatgatcga aaatgccgag cgcattaccg
     1741 ttttgacagg cgccggtatg agcacggaat caggtattcc cgattttcgt tcagccggcg
     1801 gcatatggac ggaagatctg tcgagaatgg aagcgatgag tcgtgattat tacgaacgat
     1861 atccaaaatt gttttggccg aagtttaaag agctttttca aatgaaaatg accggaactt
     1921 atcagccgaa tgacgggcac ctttatttag ccgatctcga gaaaagcggt aaggatgtca
     1981 aggtattcac gcaaaatatc gacggactgc atctcaaggc gggaagccgg catgtatatg
     2041 aactgcacgg ttcgatccaa actgccgcat gcccaaaatg cggggtgcgc tatggtcttg
     2101 accacattct tcaagaagaa gtgccaagat gccatcgcgt caatggcaag gggagagaat
     2161 gcggattcat attaaaaacg gatgtcgtgc tgttcggcga tgccgttcag cattttgaca
     2221 cgctttttga agtcctcaac gaatccgacc tgcttttggt gatcggcact tcactcgaag
     2281 tggcgcctgt caggtttgtt cctgaagaag cgcacttgat cccaggcttg aagaaagcga
     2341 tgatcaatct cgataagaca ccttacgatc atttatttga tattgtcatc catcaaaaaa
     2401 tcgccgagtt tgttcggaag cttaactgtt aaaaaggcgc tccagaccgg agcgcctttt
     2461 tctgagcttc atcacaattt tttataataa aaaacggatg tatcgaagct gccgtctgca
     2521 gattctgcgt atgcgggaat gcggccggct tcggcaaagc cgagcgaagc gtaaagaagg
     2581 ttggacgggt ctttttccct tgtatccagc acgagaagag atctgccttc ctgtttcgcc
     2641 ctgtcgatcg ctttttccat taatgatctg gcgacgccct gccgcctgaa ggcgggatct
     2701 gtcattaact tgcagatttc cgctctgtgg cggccgtttt gttttgtgca taagtgcaat
     2761 tgaacacttc ctgcgatccg gccgttttgt ttggcaatcc ataacaccga atccggtgtg
     2821 acggctgttt tccaataagc ctccgccagc tgctcatcaa gcgggggcag aaagccgatc
     2881 gatgccccgt catcgacgac tcggatgaga agctcggcca attgattggt atattcggca
     2941 gtcgaatgca gctcttcaat tttcatttat tcaccccatg atataaagat aactgcatca
     3001 taatcagaaa acggtttgtt tggcaacaag tgtgtcagat aatcacactt gcgggaggaa
     3061 ataaaaaaat ccccttcagc aggggatcag gcatgggggg ttattcatga acgggtgtca
     3121 tcgattcatc aagtgttgca aatgaatacc ccatgttttt taaatttgtc agcaataacg
     3181 gcaatgattg aaccgttgaa ggaatatcat gcatcaggat cacgatcggc tgttttgtct
     3241 gccgcttttc cagcatattc agctggttca tgacttccgg aacgaatttt tggcttctgt
     3301 atttccagtc caggctgtca atattccagt cccaataaat aaatccgttc tttttcagca
     3361 cttttttctg cgcttcggtc agcgaaggtt tgcttccgta cggcgttctg attaaatggg
     3421 tttcaacccc ggtgatagac ttcagcgttt tttgagcctg cttcatttcc agatgaggag
     3481 aattggcgcc tttataaaat tgcttttggt catgggtcac cccgtgaagt ccaagtgcat
     3541 ggccctgctg cttcatattg agaacggctt ctttgtgaag cttcatgttc ggttcgagca
     3601 tgaagaatgt cgctttagca tcatgttcgg ataaaatttg cagcagcctt tggcttacgg
     3661 ctgaaggccc atcgtcaaac gtcaaataaa ccgttttttc cttcgatttt tcttgctttt
     3721 tttccgcagc agctttttgc ttctcttttt cctgcttgcg cttttcgatc tgctgttttg
     3781 tgctcaagtg atcgagaagt tcgccttgcg ttgctttttt gagcggaacg ctgtctcctt
     3841 catgcctcat ttggctgttt tccgacaccg taagctctct tttctcagta gcggcagagg
     3901 actgtgaaag gtcccatacg tacaggagaa tcagacacaa cacgaaaaag cacgctgctt
     3961 tcgtcaacaa ataagctaca gatggggcag ttttttttga tacttggcgc atgtcactct
     4021 ctccgtatca tttttctcgt tccaattcca ttatgagata gaatgctagt ctcataaaat
     4081 aatggatcac aatgtctaag tatacaggat tggaaagaag atgaatacag gatgaaggga
     4141 aaaatatatc aaattttaag agaaaatgtt gaacgatagg gaatgctgtt tttttgatcc
     4201 tgaaggcgga aaaaagtttt tggaaatatt gcactatttt gatcggcagg gtcgtgttag
     4261 aatggaatgg agaaaattca gaagtcaaca aaaataaggg gatggagaaa tgaaagttct
     4321 ttttaacggc cggctgatgg aacggagcga gtgtgcggtt gatattgagg acagaggcta
     4381 ccaatttgga gacggcgtct atgaagtcat ccgcatttac aatggaattt tgttcacgct
     4441 tgatgaacac attgcccgct tatacaaaag cgcagccgaa atcggaatcg acctgtcttt
     4501 ttcagaagcc gagctgaaaa gccagctgaa agagctcgtc gacatcaatc agaggcggga
     4561 cggcgggctg tatcttcaag tgacaagggg aaaagctccg aggaagcatc aatacggagc
     4621 agggcttacg cctcaggtga cggcttatac atttcctatt cagaagcctg aaaaagaaca
     4681 gcaaaacggc gtttcggcta ttactgcgga cgacatgcgc tggctgagat gcgacattaa
     4741 aagcttaaat ctgttgtaca atgtaatgat caagcaaaaa gcacaggaag cttccgcctt
     4801 tgaagcgatc ttaattcgcg acggtttggt gacggaaggg acgtcttcaa atgtttacgt
     4861 cgtcaaacaa aatgttatct acacccatcc tgtgacaacg ctcatcttaa acggcatcac
     4921 gcggatgaaa gttcttcagc tgtgtgaaga gaacggcttg aattacgaag aaaaagcggt
     4981 gacaaaggat gaattgctga atgcggatga agtattcatc acgtcaacga cagccgaagt
     5041 cattccggtc acatcgattg acgggcaaac aatcggctcc ggagcgcccg gaccgctcac
     5101 aaaaaatgtg cagaccgctt tgcaaaacag cattttgtca gagacagcca aaacggttta
     5161 acaaaagaaa aacgccgctt ccatgaggaa acggcgtttt tttacttgcg gaaaccgaac
     5221 aaaattgaaa agagcggcga taaatatagg aaaaacacaa acggcaaata ttcaatgacg
     5281 ggaacgccga gcgcgctgga catgaacgcg ccgctgactc cccaagggat catcggattg
     5341 attaatgtcc ctccgtcttc aagcgatctc gacaaatgct tccggtcgat tccgagcttg
     5401 tcatacagct ttttaaagga ctgtccggga atcaagatcg ataaatactg ttcgcctgtc
     5461 gccaggttca tgccgatgct tgatgaaacg gttgagaaca caagccggcc tttcgtatga
     5521 atgcccttga ttacaccttc aagcaggctt gtaatcaggc cgattttttc catgagaccg
     5581 ccgagcgcga atgcgatgat aatcagggaa acagagccca tcatcgattg aaggccgccg
     5641 cggtttaaaa ttttctcaac ggcttcagtg tcggctgaga aaaccggacc attctgcatc
     5701 gctgacaaaa acgatgaaat gctggcgtca ggctgtatca acgcggcaag aattccggcg
     5761 gaaacgattc ccgttgcaag cgacggaatg acgggcgttc gtctgacagc aagtacaatc
     5821 acaagaagag gcgacagaag cgcccagacg ctgatgttaa ctgtaccttc tattccgttt
     5881 atgatcgcat gaatgttttc ggtagaagcc ggtgccgccg ttaaagaacg gcccatgaaa
     5941 aagaaaagca aaatcgtgat caaaagagcg gggatcgtcg ttcccgccat atgtctgata
     6001 tgcttgaaaa tgggaagctc cccgactcct gcggcaaaat tggtcgtgtc agacatcgga
     6061 gacattttgt cgccgaaaca ggcgccgcaa atcacggctc ccgccgccca tgtcagggga
     6121 acgccggccg ccgcggccac gccgatgagg gcgacgccga tcgtgctgac cgtcgtaaag
     6181 ctggagccga ccaatgaact gatcacaaga cagctgaaaa gtgcggtgag cagcaggtgc
     6241 tgcggttcaa tcaggttcaa cgcgtaaacc gttaccgtcg gaatcgcgcc gctgtactcc
     6301 cagactccga ttaagatgcc gattaaacaa aggacgataa tcggctgaac gccattccgg
     6361 atgcctgaga caatgccgct ttcaaggtct ttccaggaat ggcctttcac cgcgccgaca
     6421 gcggctaaaa aaccaacgca aatcaacagc ggtatgtgcg cttctgcttt aaatatgaat
     6481 aagcaggtga aaataatgaa caatatggcc aaaaacaata gagccgatat ggaaaacgat
     6541 agacgttttt cgtttgacaa atcacacacc tcattagaag aaatatctct ctttaatact
     6601 ttgatgcttt tgtgcataaa cgtattataa cagaaaaata gattatatac ttaaattaaa
     6661 atatttcaaa catttttcaa aggttcgccc attctatttt gaaagcgctg acttttttaa
     6721 gatataatag attagagata ggcatgtact tgatacacgt ttcactgatc ctttagccaa
     6781 aataggggga aatgcgaatg tcttacactg ttcagaaaag ccggttttta gatgaggaag
     6841 cgatatggtt ggaaaatgat gatttagagg ctgtccttgt gcccgggtgg ggaagcaatt
     6901 taatttcact gaagtggaag ccgagcggtt tgaaattgtt gaaagcgcct gaaacaaagg
     6961 aagaatatga cgcgaatccg tttttattcg gaattcctgt tctttttcct cccaaccgga
     7021 tcgatcacgg aagatttaca tatgcgggaa gaacgtacga gctgccgatc aatgaaaagc
     7081 cgctcgaaaa ccacctgcac ggatttcttt acgataaaaa atggacggtg gaaaaagtgg
     7141 aggcaacaga agagaggatc atcgtgcaga cgaagctgga ctctgaggat catcccgata
     7201 ttaaagcgat ctttccgcac tcgttttcca tcaccatcac ctacacgtta gaagggcagc
     7261 atctgaaaat cgatgcatcg gctgtcaacc gcggtcaaga cccgatgccg atcggattgg
     7321 ggtaccacac atctttccgc tatcctttaa acgaagcagg agataaagaa aggtgcctgt
     7381 ttactcttcc tgcctcaaag cgatggacgc tgacagaccg catgctgccg acaggcgagt
     7441 atcgggtgac agaggagttc aaagcgggaa aaatggcagc gggagaaagg cttgacgata
     7501 tattggcagc tgaacaagac caggaaggaa acagcgctgc cgtcattgcg gacagcctcg
     7561 ccggcattcg cgtccgctac caatgcgacg gtcattttaa gcactgggtc gtgtttaacg
     7621 gtacatcaga tcaggatgac ctgctttgta tagagccata tacttggatg acgaatgcac
     7681 cgaacctcaa ccttccgaag aatgtgaccg gatttcggga tttggggccg caggaagagc
     7741 tgacgatgcg cagcaaaatt gaggtgggcg gaatataatt cgatattccg ccttttacca
     7801 tgagctttta tcaagcgtaa atgctgtatg ggacgcttgt ttgccctctc tccaatccaa
     7861 ttgaaccgtt accttgcggc cggcgaattc ggcttcttca agctcttcca aaaaagaaac
     7921 ggattgttct tttgaccctc cgccggggag ctcgcctccc gcgtaatctt tcatcggcgt
     7981 ctcgacttgg gagttcaaaa cgatttcatc gccaaacttt gttaccattg tttatggtca
     8041 agtaatcata tatactctca ctattagaca agtatccgga agattattaa gaaatctgtt
     8101 gattaaaatg agatggaaat attgtaaaaa cttaacattg ttggtttatt ttatgttaca
     8161 atacatatga aaataagggg gaaagaaggt tttttaatga agaacatttt tgtaagtcta
     8221 ttggtccttt gtctagtctc tattagtgct ttcatcggta ttgaagatgc ttttgctgca
     8281 gaggaattac aagaagaggc ttattctgaa tctattaaaa gcgcagacga tctacaatat
     8341 gatgttaata aaaatttgac tcaggaagaa ataacatcta gatttaacaa gataaataca
     8401 aaatacgatg ttggtcaggc tttttctgag caggatgctg agtttataaa gttttatgcg
     8461 gattctcaac tggaaactcc ttccgagtta aatgatggga tatcaattag tgcaattcaa
     8521 tggtatccag gtcaaacagc cagcaaatct ttcaatactt caaaaagttc taatggagtg
     8581 aaagttaaat tctctgggaa agtctatggt acaattggta ttgtaaatca tagttataga
     8641 gggaaattga gtgcaaaaat aacttctgga acatctaaag taaagaaagc attgaaagta
     8701 cgggtaactc actcggctta tgggttggta gggaaaaaat caattggcat tgtatataac
     8761 agtggaaaat cttctacggg aacaaaatcc aaagtttcta tggataatac tgttaaatat
     8821 agtgctcttg cagttgttta tacctatacg aatgcttatg tatcagttac tacaaaaaca
     8881 ggttctttca acaagtatgc tttctaatga tatgatagag aaggagagat tgctttgatc
     8941 aatttttcaa taataaatgt gatcattgta ttaggagtct tactattaat tgtttgggga
     9001 attgtctcct ttattaacag gttaaggaaa tcaagaagat cataacatga tgagaggccg
     9061 gacatttgac cggcctcttt taaaatcgtt attttacaat cagcagcgga atctccgatt
     9121 ttgtcgatat cttgtcgctg acgttgcctg gttattacat tgtttcaacg agctgacttc
     9181 acccgtaacg ggcatttttc agctgtgggg agaaaaacat ttgccgcagc ttcctttagc
     9241 acaatgcttt gttcagataa cagcttcgct ctctgccgga cccacggagc ttttccctga
     9301 gctggtgttg atatacttgg atgacgaatg caccgaacct caaccttccg aaggatgtga
     9361 ccggatttcg ggatttgggg ccgcaggaag agctgacgat gcgaagcaaa attgaggtgg
     9421 gcggaatata atcgatattc cgccttttac catgagcttt tatcaagcgt aaatgctgta
     9481 tgggacgctt gtttgccctc tctccaatcc aattgaaccg tgatcttgcg gccggcgaat
     9541 tcggcttctt caagctcttc caaaaaagaa acggattgtt cttttgaccc tccgccgggg
     9601 aattcgcctc ccgcgtaatc tttcatcggc gtctcgactt gggagttcaa aacgatttca
     9661 tcaccaaact ttacgaccaa cttttccaaa tatatatcgt ccagctcccc gcggtcgcct
     9721 gtccaataga ggtctccgcc aaatagcgtg cggccttcta tctttttgat cacggcctcc
     9781 caatttccat cggcgctttg tccgttccat ttcgggtatt ccgtcatata gaaaccgatc
     9841 agtctgccgc cgaaataaac ggtgcaaaag gccgtgaaaa gggaagcaat gaaaagaagc
     9901 ggccgcttgt attcctgttt catattatcc accgcctaaa aagttctgct ttatgatcat
     9961 aaagcagaac aatcggaaaa aaaagccgct ctcttaaatt ttaagggaac gggtgcgggt
    10021 gcaggttcag ctgttctggt gttaacggct cttctgcaaa gccgagctcc ttcggcaccg
    10081 tgaaaattct ctcaagtcct tccaggcgga tgaagcgctg tccgaatgtc atcggaatca
    10141 ggcccgggat aagcactttc acacagtaaa gtccgttccg tttgataaca ggggaagtct
    10201 ggtcaacgac gatcacttca agattgagac tccggaaagc ttcaagcagg tcgcagagat
    10261 cttcggttaa atcaaggtgt ttctttcttt ttttaaaggc atcgtcgaat gtttgcagag
    10321 gccggctttg attcagcaaa aaccggaggc gctcttcagc ttcgggcagt ccgtacatga
    10381 agctgtgatc ctccatttcc tgcactaaag caggattgcg gagcatctgg tgatatttgc
    10441 tcctttcaga ttcaaatttg cggtcgtgct tcaacatcat gcctgccagc tcatgaaggg
    10501 cgcttttcac cgcttttacg ggatcggggt gggcccctgc ggaacaaatc agattcaatc
    10561 cttcccgttt tctgtttttg gcgatcgccc aaacgcttgg aatgccgtat tccatcgttg
    10621 aattaaagac atgcagatca tatcccgcca cacttcgcac cctctctgtc atgaggcgta
    10681 attccgaatc ttctgaagag ccgagatcca gctgccgaag tgggagcctg gcgtaccagg
    10741 caagcaaaaa tgaatcgcgc tcagcagctt ctagtatggc atggaaaatc gcttcctcca
    10801 aactccctcc aagtgcacag ccgttcgatg tttcatagac gaagctgtct tcgcgcccca
    10861 ggctgtaata ggcgagcgat tcgggaatga gaatcggccg tttctgcaaa aatgaatagc
    10921 cccataccca gcggagaggg cgggccgggt gaaatggctg aaaaggaaaa tcgggatgca
    10981 tgtattgttc cgcttgatgg agcccgactt ttgccgggtt gagcgcacga tcctttacat
    11041 tttcgtaggt gtcatgtacg atcgtccgtt tgccgcgcgg ttcaattccg gaatagcgtt
    11101 ccaaaccctc taaaatggcg gtcaattcgc tgtcttcata cgaatggctc cgccctccga
    11161 caccttcatt tcccgtccat aaaggcatat tgacgatcat atcggcgaac ggcagaatcg
    11221 cgtcataaat tttggcgttg aatatccccg ttctatgatc cagatagtct ttggcgagcg
    11281 tttgttttaa atcgtccgtg tttcgcacgc gaaagctgtc cgggttcgtt ttcagactgg
    11341 gccgaagcga tatccgtgcg gattccgctc cgtcttcagg cagactcccg catatagggc
    11401 atgtcggttc cgggatgaaa gcgtggagcg aactttctaa cgttttcaaa ttgacgatgt
    11461 aaaggttttt tatcaaccgg ccgcacccgc cgttcatgat gttgtcgact tctgtgcaga
    11521 tcaggctgac catttggcgg cagccggtct ttgaaaccca cggatcgcgg cttatgccat
    11581 tgcttttttg ttccagttca agggtctctc tgctgtcggg gccggagata taccgcctca
    11641 tatcggcgca ttgggaacat cctgacgctg acggattaac gagcggtccg atgacccctt
    11701 cgccaaaaga tgcaaacccg cgaagccacg gaatccctgc cgcccttagc accttttccg
    11761 cctcgcggta taataaaggc cgccaagcat cgtgcagcac aagagcgaac gcagtctcct
    11821 ccggtatgct gttctcaaaa tcagaccttc ggataatgtt atattcagca gataattgtt
    11881 gtgatgcgtc ttctgccatc aatccttcgc caatgaccaa aatgcagcgg ttcatcaaga
    11941 ttcctccttt cgcaactgca cgcagtaaat gcctgccagt ttttctttga aaaatggttc
    12001 agcaggcagc tcatagacat aaagctgcaa gccgcagttg tttttcaagg cggaaagcag
    12061 tgtttgctgc aaatcagcgg aaacgggggt agcaagcttc aggtcactag actccagcaa
    12121 aacatccgcg cctttcacag ggtctttgtc tgtcagcgcc cgttcgagcg cttttctgag
    12181 agcgaatgtg atgttgagtc cagaacttcc gtaccagcgg ccgcgaattc ccgcccatgc
    12241 gacagggaag ccttgtatgt tttttcctaa accgatttcc ggtttgccgt acaagactgt
    12301 cagcgctttt aaataaaatg cggtatgccg gtcttccatt ccgcctagct gaacgaggga
    12361 aatcgtttct tttccgcttt tgatccgttc tcgcaaccgg tgttccaagc atttctccaa
    12421 tccccttaat acgccttcag ccagcgtttc cccggcggcg atcgcgaaca actccccgtt
    12481 actcggataa gaacggttca accttgatgc atacatttca atacccgcca gcccggcttc
    12541 ccgccgcgcc tcttgatggg tcaaaccgac cgacaccgtc tcgggcaaaa gctccgcagg
    12601 tccggaagag agcgggtctg ctgtctgaac aaagcattgt gctaaaggaa gctgccgcaa
    12661 atgtttctct tcccacagat gaaaaatgcc cgttacaggt gaggtcagtt cactgaaaca
    12721 ttgaaataac ctgctttctg cttctcttcc ggggcgctcc gaaagtttcg cttcaaggtc
    12781 gcagatgagt tcaggcaaat ccttgccgca agcgaagtcc ggatgcggaa gaaacatatg
    12841 ccagccgcct tcgagcgttg ccaaatcaat cagatacact tgattcttct tagataatgg
    12901 tgcaatctca gcagttgctt tcatcaattc gaacacaata acgtttgcca gcatgtcttt
    12961 ccctgccgaa ggaaaagttc gaagagcccg ttcttcatgg agcgcagacc gatggaggcg
    13021 cctccaggca tccttcaggc agccgtctcc ttgttgatga aagacagggc ctgccagtcc
    13081 gacttgtttc aggcagatcc cgggtatgaa gcctttgttc tcttcgaggc aaaacgtttg
    13141 aagatcgcgg agctcatctg tgaagccgcg gtcagagaca tacagaaccc aatcggcaga
    13201 tcgcaccgct tcccgccagt gttgcgtttc ggcgcagcca atctccagtc cgctttcggt
    13261 ttgccctgat atttctgcca gttcgtctaa agcgtgcccg gatgcatccg tcacgatcgc
    13321 acggattctt gaaaaaccgg aatcgatcag cgaccggacc aattttgtga gaaaggagcc
    13381 ggcccctata gccaatattt tggtttgacg cgacagctga aagcggtaag cgccggaatc
    13441 ggcaaagctc tcaataaatt cgatttgggc ttcaaacgtt tgaagcactg agctttccag
    13501 tttgtgcggg tgatcccggc ttacgtcgcg aacgaacccg tttttataaa gcatttctcc
    13561 gatttcatat actctctttc ggtacggagc ctgcagccct tttgtcaagt cttcaagcga
    13621 atgttccccg ttgaacatcg gcagaagttt ttcgatccat tgagcaatcg aagatccttt
    13681 tatgcgaaac gacccggaat tatttctaaa atatgcgccg ccgttcggat caggaagaaa
    13741 ccatgtatcc tggtttactt ttaggcgagc ggaagcagtc aggtgtgtca tgctcttcct
    13801 ccttctatgt tttaaaaaca agacatacca ttatatgtaa ttttgtttgt cctttatgca
    13861 atagaagacc cctgcggcaa aagaggcagg ggaagtcttc ttttttataa aaaaactaca
    13921 tgcctccgcg ccaacagctc caacagcaat ggcccgcgca gctccaacaa ctgtggccca
    13981 tgcagctcca acagctgtgg cccatacagc tccagcagct gtggcccgca cagctccaac
    14041 agctgtgacc cgcgcagctc caacagctgt gacccatgca gctccaacag ctggcacagc
    14101 ttccgcagct ccagcagctt gcgcagtgtt taacattggc gtgatgacgg tccgcatccc
    14161 aatgcgtcat atcttctgcc tggaattgat ccatctccaa cgactgcagt tcatcatgga
    14221 atggttgcat ttaatatccc cctcatcgat aaaatttttt gaccaaaaca caataaaaaa
    14281 agaatgaaac ataagcaaag tcagattaag tcaaataccc cgggtactca caagatcaaa
    14341 ttatgaggtc tgttaggtgg ttgttactaa tttgaacgcc tatttttcct gttattggat
    14401 ttcgctggag aggggctttt attttgcggc agtttattga tataaagatc gttgggactg
    14461 aagagagggg ggacactaag taaaaccaag aatgcggggc aaggcggaga aagaaatcaa
    14521 ttgtaagtca tgtggagtga aagtcaaatt tcaagggaaa cgtctaaagt gaagaaagcc
    14581 tagaggataa aggtaaccat tcggcttagc aggaaaaaat caattggcgt tgtatatagc
    14641 agtagaggat cattcgcggg aacagtgccc ttgcagtttt atactgatgc aaatgcttat
    14701 gtatgactgc aaaaacaggt tctttctaca agtatgtttt catagagaag gagagattgc
    14761 attgattcaa taataaatgc ggtcatagta ttaggagtct tccctatcca ttgtgtgggg
    14821 catgatctat attatgaaca ggagaagatc gtaacatgat gagaggccgg acatttgacc
    14881 ggcctctttt aaaatcgtta ttttacaatc agcacaggga tctccgattt tgtcgatatc
    14941 ttgtcactga cactgccaaa caggagcttt ttcaggcggt tttggtcgcg cgtacccgtg
    15001 atgacaaggt cagcgccgat attttccgca tgttgtagaa ctgcgttggc cgggtcgcct
    15061 tccaacacct ctatttccgc gtcgtactgg ttttcgctta atatgatttt cgctgccgca
    15121 atcgcttctt ccgcgctgtc ctcatagatc atgggttcac cggccaagtc tgaatcgtgg
    15181 gggacccggg gcgcggccgg gaagccgctg taaaggtatg gcgcgccggc agcgggtctt
    15241 tcagtcgcgg cctctgttct cacttgcctc ggttcatgga catgggcgac ggtcaattgc
    15301 gagccgagcc ttttcgagag gtcgatcgct tttttcagcg cttttttgct ttcctctttt
    15361 ccgtcaaacg cgacaatgat ccggtcagct ttaaacaaat tgatcattcc tttcagaatg
    15421 gatttacttt tatattaccc gttttcccaa caaatctaac gaaatatgag aatatgaatc
    15481 aaaagcccgc cattcgccaa aaaaacaaat tgacaaataa agggccgtac tataagatgg
    15541 aaaatattaa taagattgga gggtatcgtc atgtttagaa atatcaaagc atcagttcaa
    15601 caacaaaagc accttaacgt gacattttta taccttcctt acgatcagtg ctctgtttca
    15661 ctttaacaat tttcaaaagg aaggcgcatg tcgcgtgaac aagcgtacat gcgccttttt
    15721 atatgaaaaa aggcatgctg gtacacagtg tgcctttttt ttctgagaaa aaacattctg
    15781 ttcccgatgc ggagcagcat gtttttctaa taaataaacc gcacataagg aggaattttt
    15841 tatgccgagt atcagaaaaa acgaaatcaa agattgtaag gaaaaacttg aaggcggcta
    15901 aaaaaggaga ggatattaga tgttttctgt tttatggaag ctgggctggt tttttaaagc
    15961 ctcttggcgg cgctacacga tagcagtcgt cctattgatt attgtaaacg tattggaaat
    16021 gtttccgccg aagctgcttg gcaacgcgat tgacgacatg caggcaggca ctttttcaaa
    16081 ggccggcatg ctcggctata tcggtttatt tctcgcgctt ggcgcagttg tttatatctt
    16141 gtcctattat tggatgtatc agctgtttgg gggagcgaac ctggtcgaaa aaatcctcag
    16201 atccaagctg atgggccatt tgctgaaaat gaccccgtct ttttacgaga aaaaccgtac
    16261 aggggatttg atggcgaggg cgacaaatga tttaaaagcg atttccatga cggcgggctt
    16321 cggcattttg accttggtcg attcgacgat gtatatgctg acgattcttt tgacgatggg
    16381 ttttttgatc agctggaagc tgacgcttgc ttcgatcatt ccccttccgc tgatggcggc
    16441 tgccatcagc atctacggga aaaaaattca tgagcgtttc acggaagcgc aggatgcgtt
    16501 tggcgcttta aatgatcgag tgctcgagtc cgtgtcaggg gtaagggtga tccgggccta
    16561 tgtacaggag aaaaatgatg tcagccggtt caacagcatg acggctgatg tgtacaagaa
    16621 aaatatgaaa gtcgctttga tcgattcgct gttcgaaccg acggtgaagt ttttggtcgg
    16681 gatcagctat ttaatcggtc ttggctacgg cgcctatctt gttttccgca gccagctgac
    16741 attgggtgaa ctcgtctctt tcaacgtgta cctcggcatg ctgatctggc cgatgtttgc
    16801 gatcggagaa ctgatcaatg tcatgcagag gggaaatgct tcgcttgaca gagtaaatga
    16861 aacattggca tatgagcctg atgtgagaga gcccgccgaa cctgaagcag cggaaccggg
    16921 cgatattgtg tttgacgggg tcgcttttac gtacccgagc tccgcgtcgg aaaacctggc
    16981 cgatatttca tttaccgtat tagaaggaca gacggtcgga gtcgtcggaa agacgggaag
    17041 cggcaaaacg acgttagtca agcagctgct gaggcagtac ccgaaaggaa aaggaacgat
    17101 caccatttcg ggcgtgccga ttgaccgcct gccgcttgat cagcttcgca gctggatcgg
    17161 gtatgtgcct caggaccacg tgttgttttc aaaatcggtg aaagacaata ttttgttcgg
    17221 cggacgactc gccgaggaac gcgatttata cgatgtcatc tctgcagcac atctgaaaaa
    17281 ggatattgag atgctttcag acggcttgga gacaatggtc ggagagaagg gcgtcgcttt
    17341 atccgggggg cagaaacaaa ggatttcaat tgcgagagcg atgattgcgg agccccatat
    17401 tttgatcttg gatgattcgc tgtccgccgt cgatgcgaaa acggaagcgg cgattattga
    17461 aaacatccgc agcaggcgga aaggcaaaac gacctttatt acatcacatc ggatgtcggc
    17521 cgtcgaacac gccgatttca ttctcgtcat ggaaaatgga aggatcgttg aaagagggac
    17581 gcatcaggaa ctgatcggcc ggaaaggctg gtattttgaa caatacgaag cacagcagct
    17641 tccttcggga gaagaagggg ggactgtagc atgacaacag gaaaaaggct tttccaatat
    17701 gcgctacttt acaaaaaaat tctcatctgg gcgctcgtca tgctgacgat tgccgtcaca
    17761 gccgagctga cgggaccgat gatcgccaaa aagatgatcg acgatcatat tcttggaatt
    17821 gaaaaaacgt ggtatgaaac gacagagaag acgaaatata ccgtttccta taaaggaaag
    17881 gaatatatca gggaggacag gacagactct tcagctgaaa agctgcagga agttcacatc
    17941 tttcaagtcg gcatgaacta ctactttgtg gaggaaccgg tttcctttga cggagagcgg
    18001 acggtatccg gagaagatct gagaatgaca agcggagacc ggacggaaac ctacaaggcc
    18061 gatcgcctgt ctttgtcaga agtgtatgct ttttacgagc ctgaaatagg agggctgatt
    18121 tcactcgttt ctatttattt cggccttctc gtcttctcga tctttttcca ttacggccaa
    18181 ttctacctct tgcagatgag cgcaaaccgc atcattcaaa agatgaggca ggatgtattc
    18241 gccaacattc aaaggctacc tatccgctat tttgataatt tgccggcagg aaaaatcgtt
    18301 gcaagggtga cgaatgatac cgaagcgatc cgcgacctgt atgtgaccgt tctttcgacg
    18361 tttgtcacaa atatcattta tatggcagga atattcgccg cgctgttttt ccttgatgtc
    18421 aggctggccg gcgtctgtct gttgattttg cccctgattg tcatttgggc ggccgtttat
    18481 cgaaaattcg cttctggcta caatcataaa ctcaggtcaa tcaacagcga gatcaacgcc
    18541 aaaatgaatg aatcgattca aggcatgccg attattcagg cattccggcg cggacaggac
    18601 acaaaagaag aatttgaaca gctgaacgag agccactttc attaccaaaa taaaatgctg
    18661 aaattgaatt cgcttatgtc ccacaacttg gtcaacattc ttagaaatgt gatgttcacc
    18721 gctttaatct ggtatttcgg gggagctgcc ctgaacgcgg aaggaatgat ttcaatcggc
    18781 gtcctttatg cattcgttga ttacttgaat cgtttatttc agccgattac gggcattgtc
    18841 aaccagtttg ccaagcttga attggctcgc gtatcatcgg agcgggtttt ccgcctgctg
    18901 gatgagccag gcgtcgacgt caaagagccg ggcagcgaaa gagcgcgggg gcgagtcgta
    18961 tttgaagatg tatcttttcg ctatcatgac ggtgaagatg tgctgaaaaa catctcattt
    19021 gaagcgcagc aaggggagac cgttgcattg gtcggccata caggctcagg aaaaagctcc
    19081 attttaaatg tacttttccg cttttacgat attgaaaagg gcgatgtcaa aatcgacggc
    19141 agaagcatat acgatatgtc aaggcaggaa atcagaaagc agatgggcat cgttctccag
    19201 gatccttact tattttccgg cacgattgct tcaaatgtca gccttgacaa tgctgatttg
    19261 accagagatc aaatagaagc cgccttgaaa caggttgggg cacttgaaat gctcgcccgc
    19321 ctgccgaaag gtcttgacga gccggtcatc gaaaaaggaa gcaccctttc gtcaggggaa
    19381 agacagctga tctcgtttgc gcgtgcgctg gcatatgatc cggctattct tattttagac
    19441 gaggcaacgg cccatatcga tacggaaaca gaagcggtca ttcaaaaagc gcttgatgtt
    19501 gttaaacaag ggcgcacgac ctttatcatc gcccacaggc tgtcaacgat caaaaacgcc
    19561 gaccagattc tcgttcttga aaaaggccgg attatcgaaa ggggaaatca tgaagagctg
    19621 atgaagcaaa aaggacaata ctatcaaatg tatgaactgc aaaagggaaa aggaaccctg
    19681 acagggtaag ccggatcttc acccggcttt aataagcaag ccccaccctt gccttgacaa
    19741 actggtctga ttcaagctgt ttgaaaagaa aatgggcggt gtcgccggtc gatatttctt
    19801 ttccgccgtc cggcagaaca tcctgttcaa aacggtatgt cttcaatgcc ggcccgtcgg
    19861 ggagatatgt cgggcagacg atcgtccaat ccaattcaga ctcgcggaga cgttcgtaca
    19921 cacgggcatg ttcttgcgct gcgcgcgccg agcgccgttt tgattcgttt gtttcaaagc
    19981 ggtaaaggtc ctggttctgc ctcgcgttta aaataccggc cgttccgatg gtaatcagcc
    20041 gtttaatccg atgtgcgttc atggcattta tcatatgttc gatggagacg gtcaatgtat
    20101 cgtctccatc tgtgtttaaa cagctgacaa cgatatccga atcttttatt aaagactcga
    20161 cgtcatgctg gttcctggcg ttccctgcaa gcgcttggca gcatttatcc ggaatgcggg
    20221 cgccttccgt cctcctaaca agtgcgtaaa cggaataacg cccatcctct tcaacaaaat
    20281 tgagaaaggc ctgtccgaca cggcctgtac ctccaaaaag cgcaattttc aacataatca
    20341 ctcccatcgg atctatcata cgtcagatcg tccggaagaa aaagccccgc gaaagcaaaa
    20401 agttccatga taagggtgga catttgagac atactcattc aatagagaaa tcccgacaaa
    20461 ttgaatcaat tcccaattga tgctcaacat cagctgcatg ccgactcctc ctttatatca
    20521 gcatatgaaa aaaggagaag cgggtgcggg ctttcataag atatgccaga ggtgcgggcc
    20581 gccgccccgg caatgaatgt gaaggtttgt cgacacgcta aagaaggtgc aggatatgca
    20641 ccttctgtta tccatgaata tgaagttgtt taaaattgtt gaccgcccat agatgcttga
    20701 gcttgggaaa ctaaacgttt tgtaatttct ccgccgacag aaccgtttgc acgggaagtc
    20761 gtgtcagcgc cgaggtttac gccgaattca gaagcaattt cgaatttcat ttgttcgatc
    20821 gcttgagctg ctcctgggac aaccagttga tttgaagaat tttgattagc catttgtatc
    20881 aaactccttt ataaaaatgg tatggttggg ctgactggag ttgcaccagc tgccggcttt
    20941 caccaaaaga aaaccgctgc cttctcggct aaagcccaat gttggtttgt actacgtatt
    21001 atggtggatt cgataaaata aatgcgtgct tcaatctggt aaatgttgaa aggcgaaaag
    21061 gccgggaatg gggcaagcta aggaaaaaag caggaggatg aagcagatga tgtgtccagt
    21121 gtgcaatggg attctcgtcc agacaaggca ttgtccgaag tgcggcgggg aaatggcgga
    21181 cgcggggaga gcaaccgatt ttttcggtcc gtacagtccg tatatggagt ttgattcatt
    21241 taaacaaacg caaaccgtat gcgttcattt atatacttgc caggactgta cttatgaaga
    21301 aaccgttgaa attgaaacga ccgaagcata gcagcacgga gggccgcagc atgcttcggt
    21361 catggagagt gtttaaatcc gctattcttc agaacggatg cgaagctccg tttctttatc
    21421 aaagaagtgg gctttattca tgtcaagcgc aagaggaagc gtatcgccgg cctggacgtc
    21481 ggttcttgaa tcgactctgg cgatgaacgg ctgcgtgccg gcttgcgaat aaagcatcgt
    21541 ttcggcgccc atcagctcag ctacctcaat tttcgcatcg atttttgagt cttttgacgc
    21601 ttcaatgaaa acaggctcgt catggatatc ctcaggtctg attcccatga tgatttcctt
    21661 gccggcatag ccctggctgc gcagaacttt catttttcct tccggcacgc gaaccgaaac
    21721 gccgtcaaat gtaaacaagt cttcttttag agtgccggtg aaaaagttca ttgcgggaga
    21781 accgataaag ccgccgacaa acacgttttc cggattttca tagacttcct tcggcgcgcc
    21841 gacctgctgg atgattccgt ctttcatgac gacgagccgc gtagccatcg tcatcgcttc
    21901 agtctggtcg tgggtgacat agatggtcgt cgtct
//
