LOCUS       NZ_CP048002            26363 bp    DNA     circular CON 17-MAR-2024
DEFINITION  Bacillus velezensis strain CACC 316 chromosome, complete genome.
ACCESSION   NZ_CP048002
VERSION     NZ_CP048002.1
KEYWORDS    RefSeq.
SOURCE      Bacillus velezensis
  ORGANISM  Bacillus velezensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus amyloliquefaciens group.
REFERENCE   1  (bases 1 to 4050296)
  AUTHORS   Kim,J.-A., Kim,P.I., Kim,D.-H. and Kim,Y.
  TITLE     Complete genome sequence of Bacillus velezensis CACC 316 isolated
            from soil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4050296)
  AUTHORS   Kim,J.-A., Kim,P.I., Kim,D.-H. and Kim,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-JAN-2020) Technical Support Team, Center for
            Industrialization of Agricultural and Livestock Microorganisms, 241,
            Cheomdangwahagro, Jeongeup-si 56212, Korea, Republic of
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 12.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009931675.1-RS_2024_03_17
            Annotation Date                   :: 03/17/2024 02:01:09
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,960
            CDSs (total)                      :: 3,842
            Genes (coding)                    :: 3,768
            CDSs (with protein)               :: 3,768
            Genes (RNA)                       :: 118
            rRNAs                             :: 9, 9, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 9, 9 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 42 of 74
            Pseudo Genes (incomplete)         :: 38 of 74
            Pseudo Genes (internal stop)      :: 15 of 74
            Pseudo Genes (multiple problems)  :: 18 of 74
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:26:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1107675
            Orig. end                         :: 1134038
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP048002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Center for Industrialization
            of Agricultural and Livestock Microorganisms.
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26363
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="5"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..26363
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26363
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16363](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16363)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(158..1297)
                     /gene="opuCA"
                     /locus_tag="GWK37_RS05650"
                     /old_locus_tag="GWK37_05655"
     CDS             complement(158..1297)
                     /codon_start=1
                     /gene="opuCA"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013353644.1"
                     /locus_tag="GWK37_RS05650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GWK37_05655"
                     /product="osmoprotectant ABC transporter ATP-binding
                     protein OpuCA"
                     /protein_id="WP_003151651.1"
                     /transl_table=11
                     /translation="MLRLENVSKVYKGGKKAVNSIDLNIEKGEFICFIGPSGCGKTTTM
                     KMINRLIEPSSGKIFIDGENIMEQDPVELRRKIGYVIQQIGLFPHMTIQQNISLVPKLL
                     KWPEQKRKERARELLKLVDMGPEYLDRYPHELSGGQQQRIGVLRALAAEPPLILMDEPF
                     GALDPITRDSLQEEFKKLQRTLNKTIVFVTHDMDEAIKLADRIVILKAGEIVQAGTPDD
                     ILRNPANEFVEEFIGKERLLQSRPDIERVEQMMNKKPVTVTADKTLSQAIQVMREHRVD
                     SLLVVDDLNVLQGYVDVEIIDQNRKKASLVGDVLRSDLYTVEQGTLLRDTVRKILKRGM
                     KYVPVVDEQRHLVGIVTRASLVDIVYDSIWGEEDQLVTG"
     CDS             1386..1532
                     /gene="allorf_1109061_1109207"
                     /locus_tag="allorf_1109061_1109207"
                     /protein_id="allorf_1109061_1109207"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MLKLYTIYVFFHVIPLTMRMFLQSLPIALISCRIIFFINCKKYDI
                     LSA"
     CDS_motif       1386..1469
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MLKLYTIYVFFHVIPLTMRMFLQSLPIA"
                     /locus_tag="allorf_1109061_1109207_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       1470..1532
                     /prepeptide="core"
                     /locus_tag="allorf_1109061_1109207_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.60"
                     /molecular_weight="2324.8"
                     /monoisotopic_mass="2323.3"
                     /core_sequence="LISCRIIFFINCKKYDILSA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MLKLYTIYVFFHVIPLTMRMFLQSLPIA"
                     /leader_location="[1385:1469](+)"
     misc_feature    1392..1410
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: medium, score: 29.41"
                     /tool="antismash"
     CDS             complement(1418..1501)
                     /gene="allorf_1109093_1109176"
                     /locus_tag="allorf_1109093_1109176"
                     /protein_id="allorf_1109093_1109176"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MMKKMMRQDMRAIGSDCKNIRIVSGIT"
     CDS_motif       complement(1457..1501)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MMKKMMRQDMRAIGS"
                     /locus_tag="allorf_1109093_1109176_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(1418..1456)
                     /prepeptide="core"
                     /locus_tag="allorf_1109093_1109176_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.80"
                     /molecular_weight="1282.5"
                     /monoisotopic_mass="1281.7"
                     /core_sequence="DCKNIRIVSGIT"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MMKKMMRQDMRAIGS"
                     /leader_location="[1456:1501](-)"
                     /alternative_weights="1300.5"
     gene            1558..2115
                     /locus_tag="GWK37_RS05655"
                     /old_locus_tag="GWK37_05660"
     CDS             1558..2115
                     /codon_start=1
                     /function="Predicted transcriptional regulators"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391264.1"
                     /locus_tag="GWK37_RS05655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GWK37_05660"
                     /product="GbsR/MarR family transcriptional regulator"
                     /protein_id="WP_014418904.1"
                     /transl_table=11
                     /translation="MEKNALDIIGHAEEHLIERIAENMHTFGMPATLGRVLGIIYMNRK
                     PMTLNELSEATGMSKTRMSQVVREMTDANLAEKVFEKGVRKDLYDVERDYYQTFISLFT
                     ANWTKAVSKNKMLYKKLNRELTELLESENLSPDIEEKARQLLDELTDWLHYYDWLSRLI
                     EFFESEEVFQHVPKIEKSSTRR"
     gene            complement(2136..2768)
                     /locus_tag="GWK37_RS05660"
                     /old_locus_tag="GWK37_05665"
     CDS             complement(2136..2768)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014471043.1"
                     /locus_tag="GWK37_RS05660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GWK37_05665"
                     /product="NAAT family transporter"
                     /protein_id="WP_115941058.1"
                     /transl_table=11
                     /translation="MFSFIIHVFISLFAVSNPIGNVPIFLSLTEGYSEKERTAIARKAS
                     VLSFIILAAFLIFGHLIFKLFDINIHALRIAGGIFIFGIAYNLLNAKKSHVQSLHHEEK
                     GESKEKADISVTPLSIPIIAGPGTIATVMSLSAGQGGIFHYISVLIGIAAVIAMTFIFF
                     HYSSFISNKLGKTEMNVITRLMGLILAVVAIGMIGAGLKGMFPILVS"
     gene            3206..3916
                     /locus_tag="GWK37_RS05665"
                     /old_locus_tag="GWK37_05670"
     CDS             3206..3916
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007409971.1"
                     /locus_tag="GWK37_RS05665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GWK37_05670"
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="WP_115941059.1"
                     /transl_table=11
                     /translation="MYCSQCGHHTDGGKFCEKCGAPQPGQGGAGQTQGQAAQTGAAAKQ
                     ASKQFALFVLDVLKRPYQTCKTTGGEQLVSSIINMVLFCLVTPIMFYILLSDGFRDVSF
                     TAVVIKPALTFALSVFCLYLLIFIALKAGGAQVSFKDSLSRFGAFLIPFTAILLLALIF
                     MLLHTTVCFTILAVGLLGAAFAVPPLMLASYQHQLTPKADIIYSVIVIYLIICVTFQFT
                     IKHYIKELMNYFFF"
     gene            complement(3958..5736)
                     /locus_tag="GWK37_RS05670"
                     /old_locus_tag="GWK37_05675"
     CDS             complement(3958..5736)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014305844.1"
                     /locus_tag="GWK37_RS05670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GWK37_05675"
                     /product="hypothetical protein"
                     /protein_id="WP_115941060.1"
                     /transl_table=11
                     /translation="MFFCKYCGQQNNEEAHFCKECGKPIGKGSRLERQAAESASQPRKP
                     IPKKTLFLWGGIAAALILLIAAYKTGAWLTSEKRLTDQFEQAVHDGDTKKLAALLTPSD
                     KKLKLNETNVKPLLAYAKKHDELLASLRGNSSEKDAVYVKKEGKTLLLFDHYELKVDPV
                     YFRVTSNYKGADLYINSEKTGTVKKADETQIFGPYAPGVYTAEAKLKNETVDVVKKQEA
                     EAAGSRNVEFDLPLDAEDVTFTPADSFKSAKGDLLINGKSVHKDPFTSVTYGPLLTDGS
                     MTAAVEADFPWGKMKTADVPINSTDVDLTLIPDQDTQQTIMDTIVKTTKQYTKAMADGN
                     TDQMTEAGSVWKEQTKEAVSGMKSSGTFLKDQYKETSFDLDSFAISQENGRWQVTVTGK
                     ELHESAYFDGNTKPDMEEAEPSFHYVLSYDTKHKKWVFEKADPASDSSGTNVKKIKNDQ
                     PKTYTSAWASSKGNTASGSVTNEQVTTFMTDYLTNQSSAVSLNNFAIMAGNLEEGSPLY
                     ADQQKLVKKLHSEGTTEVFNEVNVKSFSQKGSHLTIHTYEEFYITKAGGSPKLRTYNWT
                     YGGVVKDGRIYLTSIQ"
     misc_feature    complement(5820..5833)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.2"
                     /tool="antismash"
     gene            5868..6329
                     /locus_tag="GWK37_RS05675"
                     /old_locus_tag="GWK37_05680"
     CDS             5868..6329
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003151638.1"
                     /locus_tag="GWK37_RS05675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GWK37_05680"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_095270647.1"
                     /transl_table=11
                     /translation="MQKLSIRKAAEPDEALYELLLLADPSKEIVDDYLVRGECYTAWTS
                     DELAGVFVLLKTRPKTVEIVNIAVKESMQNNGIGRKLIEEAVNKAKQMGAATIEIGTGN
                     SSIGQLALYQKCGFRLQAIDHDFFIRHYEEEIFENGIQCRDMIRLYLDL"
     gene            complement(<6528..7329)
                     /locus_tag="GWK37_RS19715"
                     /pseudo=""
     CDS             complement(<6528..7329)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611387.1"
                     /locus_tag="GWK37_RS19715"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRVSDPVEVKQKV"
     misc_feature    complement(7550..7563)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 23.22"
                     /tool="antismash"
     gene            complement(7645..7815)
                     /locus_tag="GWK37_RS05680"
                     /old_locus_tag="GWK37_05685"
     CDS             complement(7645..7815)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GWK37_RS05680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GWK37_05685"
                     /product="hypothetical protein"
                     /protein_id="WP_155238646.1"
                     /transl_table=11
                     /translation="MKNYKGDGAVFLVIGFCLGLFLGVVFDILPYGLSIGILIGSLIDL
                     YFYARYKNNNK"
     gene            complement(7839..10004)
                     /locus_tag="GWK37_RS05685"
                     /old_locus_tag="GWK37_05690"
     CDS             complement(7839..10004)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="GWK37_RS05685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GWK37_05690"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_115941061.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 3.7e-37, bitscore:
                     124.9, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVKKKKRVPIVKQLQQTECGLCCCAMLIRFYNSNETLFELRSFL
                     EAGRDGLTIKQLKNLLVHKGFKADIYKSTILGLKKINVPFIAYWNNEHFIVVEKIKENY
                     YYIIDPANGRRKLTEEEFKKGFSSYILYAVPSESFTPNKRKDKNVWFGVLKNITNYKLL
                     FSIIVFFSLISYLLTLYVPILVQKLIDTSIEYNNLNSISNIVWITFLISILYGMFVLFR
                     GLKMISLNIFLSKNLVVDTFAHLLKLPFKFFDLRSPGDLLFRLNSMNGFRELLSTQLIS
                     GLIDLGAVVFILAYMFFKSIPLTLITILIFAINTIFMFLTRPAVAQAIDDEVAEQSKSQ
                     AIQIESIFSIAAIKISGMENEIFSTWNNSFNEVIKRFKKRSILQNVVNTVTQVFQTIAP
                     LVILILELLLFFDNKFTMGEVIAYHSLSVTFFGLTTALFGTYTQFILATSYLERVKDIT
                     ETECEKNIENAVNLKLRGNVKLENVSFSYTKHSPKVLKNISLEIREGQKIAIVGSSGSG
                     KSTLSKLIMGLYDPTEGQICFDSIPLEKLDRKQLYKQMGIVPQDITLFNSSILKNITLN
                     NKNISIEKVRKVAKAAQIDKEIESMPMKYNTPISEMGMNLSGGQRQRIVLARALLNDPK
                     ILILDEATSSLDLVNETLISKYLSEMGCTRVVIAHRLSTIMDSDFIIVLDKGEVVEVGK
                     HEELIALEGVYSNLYRSQTKKQKTYSS"
     gene            complement(10001..12952)
                     /locus_tag="GWK37_RS05690"
                     /old_locus_tag="GWK37_05695"
     CDS             complement(10001..12952)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="GWK37_RS05690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GWK37_05695"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_115941062.1"
                     /sec_met_domain="DUF4135 (E-value: 1.3e-87, bitscore:
                     292.2, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 9.7e-61, bitscore:
                     203.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDISYENNNFIRDAVINFSSPTNEVEKLRIKNKDYFGNFYTFFLD
                     FYQQKLVNTLENASKENNLKLNKHKIISSALEAFSQELIQLCIRTLIVDINERKENGLL
                     EGKDSRLRYKNYNNLIFKSEYVAGILNKYPVLTYLISSRISNKILYLKEVLENLRKNRQ
                     DIYRELKIEFDEVSNIYFSSGDTHNGGKNVLIIETNQGKIVYKPHSLSPDILFNSIVDY
                     VNNSDKILKKIYKIKTLNYKDYGYQEFIDYKECETSEKLNFYFYRVGVSLSIFHIIGCD
                     DLHHENLIAHGEYPVVIDLETLIKNNSMYKPRNNNLIDNFHEDINYSVLGTMLLPLNLQ
                     TSIFDFDLGGISNDENQTSEIWKSYIIDFEGTDEIQLTKKSVIMNSTQNRAAYNGKAAD
                     PKDYIEEILKGFTDCYNFVLENKSGFYDLVKTVGSSNLEVRQVLRATSIYARFLEASTH
                     PNYLSSFEERKELFKKINIAEGVTDKFSKKNLNELESLMCNDVPYFSTMYNSLDLICNK
                     STSIVNFFRECLLDVVLNKIKSISKTSLKKQQYYIRMSLTTTIKDSWKRTNKHNKKYRP
                     KLFGNNNKNYLECATEIGDLFLETAIWNNDRSKCTWVTPIISENNKVKLGPLNFDLYEG
                     GGVILFLALLGKETGNKEYFDLAFAGMRGIEELFLSDDKMDGRLSLFTGIGSLAYIYYH
                     LYTYTNDYKYYEKFKKYINKINEMNISGDIPLDIVGGVSSLIVFLLNLYKETKLDILNS
                     VCCKLGNTLYQCLEKNGKYNYLTGLSHGYSGFTWALCYLGHITKDEKYTTLGKELLKRE
                     NKFFDLNTSNWKDLREGEGNSDPVYWCHGAGGIALSRAFLKNLLKNKENVVDKEVDKEV
                     DKDLNCAISKLLSDGFKKTTDHSLCHGIFGNIDILLKLSELLNDIDLQEVAFKEAQNAI
                     NYIRNKGFIPGLQDHFDLNTFMLGLGGVGYSLLRLHNPVNPSLLAMEVRSYNE"
     gene            complement(13021..13227)
                     /locus_tag="GWK37_RS05695"
                     /old_locus_tag="GWK37_05700"
     CDS             complement(13021..13227)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038161.1"
                     /locus_tag="GWK37_RS05695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GWK37_05700"
                     /product="class II lanthipeptide, LchA2/BrtA2 family"
                     /protein_id="WP_025854095.1"
                     /transl_table=11
                     /translation="MKKDMVKKASGFIEEDELISLANGDNATGGATPTVVLTATIGLTG
                     TTFTVTLSAASCPTSACTKQCNK"
     CDS_motif       complement(13138..13227)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKKDMVKKASGFIEEDELISLANGDNATGG"
                     /locus_tag="GWK37_RS05695_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13021..13137)
                     /prepeptide="core"
                     /locus_tag="GWK37_RS05695_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.10"
                     /molecular_weight="3508.0"
                     /monoisotopic_mass="3505.9"
                     /core_sequence="ATPTVVLTATIGLTGTTFTVTLSAASCPTSACTKQCNK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKDMVKKASGFIEEDELISLANGDNATGG"
                     /leader_location="[13137:13227](-)"
                     /alternative_weights="3526.1"
                     /alternative_weights="3544.1"
                     /alternative_weights="3562.1"
                     /alternative_weights="3580.1"
                     /alternative_weights="3598.1"
                     /alternative_weights="3616.2"
                     /alternative_weights="3634.2"
                     /alternative_weights="3652.2"
                     /alternative_weights="3670.2"
                     /alternative_weights="3688.2"
                     /alternative_weights="3706.3"
     gene            complement(13277..16363)
                     /locus_tag="GWK37_RS05700"
                     /old_locus_tag="GWK37_05705"
     CDS             complement(13277..16363)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="GWK37_RS05700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GWK37_05705"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_115941063.1"
                     /sec_met_domain="DUF4135 (E-value: 1.1e-96, bitscore:
                     322.1, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.3e-67, bitscore:
                     224.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTNKYNLQYWMKMFPEVNNKDELQKIFLNVSGKTIQSLIRDDTN
                     IEQNKSIIDIDRVLDHKKSDFLVRNSEEFLEHNPFFHFFSPFLNCKIEEFLVKVRIEDA
                     VDNEDEFVKKVIKHIMDLMFEKAFRVLVLEVNIARLEGNLEGTTPEERLNHFLVVSLND
                     ESFLKSVYKEYEVLTSLLCVTIDDYFTYVMEIIKNTKREISSLNSKFNSDNDLGAITNI
                     TTGLGDTHQKGKSVSTIYFKSGKKIIYKPRDLTLEQGFQEVLYWLGEKNIPGILNFKRV
                     QIHTVNDSGWMEHIDYKSCFNKNEANDFYTRSGNLLCLLYLLNAVDFHHENLIAHGSFP
                     VLVDLESLFHARLKVDQIDKKSAVVKATELVDNSVQSISLLPTKISKRVGDKDISLDIG
                     GLAAYKEQLSPHKSLVIENAGTDTIKILRKNTFIKPQLNNPSIKTGSYLYSENYTGQIK
                     DGFASLYSWVMLNKDEFWDKISQTFKETNSRFIFRPTYLYTQLLRISSHPDFMRDTYRR
                     KIILHRIGIDYIQEYKDILNSEYKDLLTGDVPFFRSSIEHEHLIDSRGKRIHSILEEPP
                     IKTVKQKIFNLSKEDLKRQIDFIEMSYISNEKRLKEVTDIRFSKAASLNKIKSENWIDE
                     ATEIGEFIVENSVCGINKKQKDRMWIGPSLEGIEEDIWNANVLGFDIYNGNSGIALFLG
                     YLGEILNRKDFKQAAIETMRPIQKFISEIKEDHPYLIGAFQGISGYFYTLNKLSNLFGD
                     SELRKTSFENIGVLSKLGKFDKVYDLIGGSLGSLAVMLSIIPDITEENNKKEILKISHT
                     HCDHILSVAKNFEEQISWPGKFSAAYSGFSHGNSGFIAYLYKYFKLTNDEKLLEVIQRA
                     LRFERRLYSEDHNNWYTTENKDKLANGWCHGAPGILLSKLILKDNGFEDEYIEKEISTA
                     IDSSIRNGIGNNPTYCHGDLGVLSILNYASDLTNNINLKNRCLRTYQDLFENVLTKKWR
                     KRDLVCTRSYSLMIGLSGIGYSMIKNYAPEIVPNFLWLE"
     gene            complement(16436..16666)
                     /locus_tag="GWK37_RS05705"
                     /old_locus_tag="GWK37_05710"
     CDS             complement(16436..16666)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_ha"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884148.1"
                     /locus_tag="GWK37_RS05705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GWK37_05710"
                     /product="plantaricin C family lantibiotic"
                     /protein_id="WP_021495220.1"
                     /sec_met_domain="mature_ha (E-value: 4.9e-07, bitscore:
                     27.2, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKTKILKTPELKVTKDLNLIDPCGDVLEEIKEHEVSGAFNTWNT
                     TTTSLGGILVSEVLGNKGKVCTGTKECQGTC"
     CDS_motif       complement(16550..16666)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MKKTKILKTPELKVTKDLNLIDPCGDVLEEIKEHEVSGA"
                     /locus_tag="GWK37_RS05705_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(16436..16549)
                     /prepeptide="core"
                     /locus_tag="GWK37_RS05705_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.20"
                     /molecular_weight="3669.1"
                     /monoisotopic_mass="3666.9"
                     /core_sequence="FNTWNTTTTSLGGILVSEVLGNKGKVCTGTKECQGTC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKTKILKTPELKVTKDLNLIDPCGDVLEEIKEHEVSGA"
                     /leader_location="[16549:16666](-)"
                     /alternative_weights="3687.1"
                     /alternative_weights="3705.2"
                     /alternative_weights="3723.2"
                     /alternative_weights="3741.2"
                     /alternative_weights="3759.2"
                     /alternative_weights="3777.2"
                     /alternative_weights="3795.3"
     misc_feature    16925..16938
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.53"
                     /tool="antismash"
     misc_feature    16951..16963
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.83"
                     /tool="antismash"
     misc_feature    complement(17726..17741)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.73"
                     /tool="antismash"
     gene            complement(18050..19342)
                     /gene="eno"
                     /locus_tag="GWK37_RS05710"
                     /old_locus_tag="GWK37_05715"
     CDS             complement(18050..19342)
                     /EC_number="4.2.1.11"
                     /GO_function="GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="eno"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391270.1"
                     /locus_tag="GWK37_RS05710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GWK37_05715"
                     /product="phosphopyruvate hydratase"
                     /protein_id="WP_007409956.1"
                     /transl_table=11
                     /translation="MPYIVDVYAREVLDSRGNPTVEVEVYTETGAFGRALVPSGASTGE
                     YEAVELRDGDKDRYLGKGVLTAVNNVNEIISPELLGFDVTEQNAIDQLLIELDGTENKG
                     KLGANAILGVSMACARAAADFLQIPLYQYLGGFNSKTLPVPMMNIVNGGEHADNNVDIQ
                     EFMIMPVGAPNFREALRMGAQIFHSLKSVLSAKGMNTAVGDEGGFAPNLGSNEEALQTI
                     VEAIEKAGFKPGEEVKLAMDAASSEFYNKEDGKYHLSGEGVVKTSAEMVDWYEEMVSKY
                     PIISIEDGLDENDWEGHKLLTERLGKKVQLVGDDLFVTNTKKLAEGIKNGVGNSILIKV
                     NQIGTLTETFDAIEMAKRAGYTAVISHRSGETEDSTIADIAVATNAGQIKTGAPSRTDR
                     VAKYNQLLRIEDQLAETAQYHGINSFYNLNK"
     gene            complement(19370..20905)
                     /gene="gpmI"
                     /locus_tag="GWK37_RS05715"
                     /old_locus_tag="GWK37_05720"
     CDS             complement(19370..20905)
                     /EC_number="5.4.2.12"
                     /codon_start=1
                     /gene="gpmI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391271.1"
                     /locus_tag="GWK37_RS05715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GWK37_05720"
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="WP_003151620.1"
                     /transl_table=11
                     /translation="MSKKPAALIILDGFGLRNETVGNAVAQAKKPNFDRYWNQYPHQTL
                     TASGEAVGLPEGQMGNSEVGHLNIGAGRIVYQSLTRVNVAIREGEFERNQTFLDAIKNA
                     KDNDKALHLFGLLSDGGVHSHINHLFALLKLAKSEGLTKVYIHGFLDGRDVGPQTAKTY
                     IQQLNEQIEEIGVGEIASISGRYYSMDRDKRWDRVEKAYRAMAYGEGPSYRSAMDVVDD
                     SYANGIHDEFVIPSVITKENGEPVAKIHDGDSVIFYNFRPDRAIQISNTFTNKDFRDFD
                     RGENHPKNLYFVCLTHFSESVDGYVAFKPVNLDNTVGEVLAQHGLKQLRIAETEKYPHV
                     TFFMSGGREEEFPGEERILINSPKVATYDLKPEMSAYEVKDALVKEIAADKHDAIILNF
                     ANPDMVGHSGMVEPTIKAIEAVDECLGEVVDAIIAKGGHAIITADHGNADILITETGEP
                     HTAHTTNPVPVIVTKEGVTLREGGILGDLAPTLLDLLGVEKPKEMTGTSLIQK"
     gene            complement(20898..21659)
                     /gene="tpiA"
                     /locus_tag="GWK37_RS05720"
                     /old_locus_tag="GWK37_05725"
     CDS             complement(20898..21659)
                     /EC_number="5.3.1.1"
                     /GO_function="GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="tpiA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391272.1"
                     /locus_tag="GWK37_RS05720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GWK37_05725"
                     /product="triose-phosphate isomerase"
                     /protein_id="WP_003151618.1"
                     /transl_table=11
                     /translation="MRKPIIAGNWKMNKTLGEAVSFVEEVKSSIPAADKAEAVVCAPAL
                     FLEKLTSAVKGTDLKVGAQNMHFEENGAFTGEISPVALKDLGVDYCVIGHSERREMFAE
                     TDETVNKKAHAAFKHGIVPIICVGETLEEREAGKTNDLVADQVKKGLAGLSEEQVAASV
                     IAYEPIWAIGTGKSSTAKDANDVCAHIRKVVAESFSQETADKLRIQYGGSVKPANIKEY
                     MAESDIDGALVGGASLEPQSFVQLLEEGQYE"
     gene            complement(21685..22869)
                     /locus_tag="GWK37_RS05725"
                     /old_locus_tag="GWK37_05730"
     CDS             complement(21685..22869)
                     /EC_number="2.7.2.3"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /function="3-phosphoglycerate kinase"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391273.1"
                     /locus_tag="GWK37_RS05725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GWK37_05730"
                     /product="phosphoglycerate kinase"
                     /protein_id="WP_022553807.1"
                     /transl_table=11
                     /translation="MNKKTVKDIDVKGKVVFCRVDFNVPMKDGEVTDDTRIRAALPTIK
                     HLADQGAKVLLASHLGRPKGETVEELRLTPVAARLGELLGKEVKKADEAYGDAVKAQIS
                     DMKDGDVLVLENVRFYPGEEKNDPELAKAFAELADVYVNDAFGAAHRAHASTAGIAEHL
                     PAVAGFLMEKELDVLGKAVTNPERPFTAIIGGAKVKDKIGVIESLLDKVDNLIIGGGLA
                     YTFVKALGYEVGKSLLEEDKIELAKSFMDRAKEKGVKFYMPEDVLVADDFSNDANVQIV
                     PISEIPSDLEAIDIGTKTRETYAEVIKNSKLVVWNGPMGVFEIDLFAQGTKAVAEALAE
                     ANDTYSVIGGGDSAAAVEKFGLADKMSHISTGGGASLEFMEGKELPGVAALNDK"
     CDS             complement(22934..23164)
                     /gene="allorf_1130609_1130839"
                     /locus_tag="allorf_1130609_1130839"
                     /protein_id="allorf_1130609_1130839"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MVLSDRNAIMKADKGRGRTPFPFFHENRLSESAGLLQNVRVLKFP
                     RHFRFLSRLPWLRRRSAPCPEAAICPAAEAS"
     CDS_motif       complement(23060..23164)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MVLSDRNAIMKADKGRGRTPFPFFHENRLSESAGL"
                     /locus_tag="allorf_1130609_1130839_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(22934..23059)
                     /prepeptide="core"
                     /locus_tag="allorf_1130609_1130839_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.70"
                     /molecular_weight="4707.5"
                     /monoisotopic_mass="4704.6"
                     /core_sequence="LQNVRVLKFPRHFRFLSRLPWLRRRSAPCPEAAICPAAEAS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVLSDRNAIMKADKGRGRTPFPFFHENRLSESAGL"
                     /leader_location="[23059:23164](-)"
                     /alternative_weights="4725.5"
     misc_feature    complement(23112..23121)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 16.98"
                     /tool="antismash"
     gene            complement(23191..24198)
                     /gene="gap"
                     /locus_tag="GWK37_RS05730"
                     /old_locus_tag="GWK37_05735"
     CDS             complement(23191..24198)
                     /GO_process="GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /GO_process="GO:0019682 - glyceraldehyde-3-phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="gap"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391274.1"
                     /locus_tag="GWK37_RS05730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GWK37_05735"
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="WP_007409954.1"
                     /transl_table=11
                     /translation="MAVKVGINGFGRIGRNVFRAALNNPEVEVVAVNDLTDANMLAHLL
                     QYDSVHGKLDAEVKVDGSNLVVNGKTIEVSAERDPAKLSWGKQGVEIVVESTGFFTKRA
                     DAAKHLEAGAKKVIISAPANEEDITIVMGVNEDKYDAANHDVISNASCTTNCLAPFAKV
                     LNDKFGIKRGMMTTVHSYTNDQQILDLPHKDYRRARAAAENIIPTSTGAAKAVSLVLPE
                     LKGKLNGGAMRVPTPNVSLVDLVAELNKDVTAEDVNAALKEAAEGDLKGILGYSEEPLV
                     SGDYNGNANSSTIDALSTMVMEGSMVKVISWYDNESGYSNRVVDLAAYIAKQGL"
     gene            complement(24232..25266)
                     /gene="cggR"
                     /locus_tag="GWK37_RS05735"
                     /old_locus_tag="GWK37_05740"
     CDS             complement(24232..25266)
                     /codon_start=1
                     /gene="cggR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003151607.1"
                     /locus_tag="GWK37_RS05735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GWK37_05740"
                     /product="gapA transcriptional regulator CggR"
                     /protein_id="WP_003151607.1"
                     /transl_table=11
                     /translation="MNQLIQAQKKLLPDLLLVMQKRFEILQYIRLTEPIGRRSLAASLG
                     LTERVLRSEVQFLKEQNLIDIKTNGMTMTEEGYSLLSILEDTMKDVLGLTLLEKTLKER
                     LNLKDAIIVSGDSDQSPWVKKELGRAAVACMKKRFSGKNIVAVTGGTTIEAVADMMTPD
                     SKNRELLFVPARGGLGEDVKNQANTICAHMAEKASGTYRLLFVPGQLSQGAYSSIIEEP
                     SVKEVLHTIKSASMLVHGIGEARTMAERRNTPLEDLKKIDDNHAVTEAFGYYFNADGEV
                     VHKVHSVGMQLDDLDAIPDIIAVAGGSSKAEAIEAYFKKQRNTVLVTDEGAAKKLLRDN
                     SPSI"
     misc_feature    25362..25375
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 23.01"
                     /tool="antismash"
     misc_feature    complement(25454..25472)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 23.66"
                     /tool="antismash"
     misc_feature    complement(25582..25596)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 19.59"
                     /tool="antismash"
     misc_feature    complement(25876..25892)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.87"
                     /tool="antismash"
     misc_feature    26345..26360
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.14"
                     /tool="antismash"
ORIGIN
        1 ctcgtcagcg ccactccgag cggaacggcg acgacaatgc ctaatatgac ggcgatgatc
       61 gaaatgtata aatgctccca cgttttatat aacagttctc cgccgttcgt ctgcaaaaac
      121 ttgatcattt cattcattgt aagcgttcct ccccttgtca gcctgtcacc agctggtctt
      181 cctcgcccca gattgaatcg taaacgatgt cgacaaggct cgcccgcgtg acaattccga
      241 ctaaatgcct ttgttcatca acgacgggta catatttcat tccgcgcttt aaaattttgc
      301 gtacggtatc gcgcagcagt gtcccctgct cgaccgtata cagatcagag cggagcacgt
      361 cgccgacgag gctcgctttt ttccggttct gatcaatgat ctcgacatcg acataccctt
      421 gcagcacatt caggtcatca acgacaagca gggaatcgac acggtgctcc cgcatcacct
      481 gtatcgcctg cgaaagcgtt ttgtccgccg taacggtgac aggctttttg ttcatcatct
      541 gctcgacgcg ttcaatgtcc ggtcttgatt gcaataaccg ttctttgccg ataaattctt
      601 cgacaaactc attagccgga ttccggagaa tgtcatcagg agtgccggcc tgaacgatct
      661 ctcccgcttt taaaatgacg atccggtcag ccagcttaat agcttcatcc atatcgtgtg
      721 ttacaaacac aatcgtttta ttcaatgttc tttgcagttt tttgaattct tcttgaaggg
      781 aatcccgcgt aatcggatca agcgctccga acggttcatc catgagaata agaggcggtt
      841 ccgctgcaag ggcgcgcagc acgccgattc tctgctgctg tccgccgctc agctcgtgag
      901 gatagcggtc taaatattcc gggcccatat cgacgagctt caaaagctcc cgcgcccgtt
      961 ccttccgctt ttgttccggc catttcagca gtttcggcac gagggaaatg ttctgctgaa
     1021 tggtcatatg agggaaaagt ccgatctgct gaatgacgta gccgattttc cgtctcagct
     1081 ccaccgggtc ctgctccata atgttttcgc catcgataaa aatcttaccg gatgacggct
     1141 caatcagtct gttaatcatt ttcatcgtcg tcgtttttcc gcagccgctc ggcccgataa
     1201 aacaaataaa ctcgcctttt tcgatattta aatcaatgct gttgacagct ttttttccgc
     1261 ctttatagac tttcgataca ttttctaatc tcagcaatcc gtgcacctcc gaagggttcc
     1321 gttatttttc taaaaagtat aatctttatt ataagatgaa atttgtaaaa taaaaagttt
     1381 acaatgtgtt gaaattatat acaatatacg tattttttca tgttatcccg ctgacaatgc
     1441 ggatgttctt acaatcgctc ccgatagctc tcatatcctg ccgcatcatc tttttcatca
     1501 actgtaaaaa atatgatata ttgtcagcat gaaaagccag tgaagggatg atcagccgtg
     1561 gaaaaaaacg ctcttgatat catcgggcat gctgaagagc atctcattga gagaatcgcc
     1621 gagaatatgc atacattcgg aatgccggcc acacttggac gtgtgctcgg tattatttat
     1681 atgaaccgca agccgatgac gttaaatgag ctgtcagagg cgaccgggat gagcaaaacg
     1741 aggatgagcc aggtggtccg cgaaatgacc gatgccaatc tggctgaaaa agtgtttgaa
     1801 aaaggcgttc ggaaagacct ttacgacgtc gagcgtgatt attaccagac gtttatctcc
     1861 ctgtttacgg caaattggac aaaggcggtc agcaaaaaca aaatgctcta taaaaagctg
     1921 aatcgcgagc tgactgagct tctggaatcg gaaaatctca gtcccgatat tgaagaaaaa
     1981 gcccgccagc ttttggatga actgacggat tggctccatt attatgactg gctgagccgt
     2041 ttgatagaat tttttgagag tgaagaagtg tttcagcatg tgccgaaaat agaaaaaagc
     2101 agcacccgaa gataaccggg cgctgctttt ttaagtcagg aaaccaatat cgggaacatg
     2161 cctttcagac cggcgccgat catgccgatc gccaccaccg ccaaaatcag ccccatcagt
     2221 cgggtaatga cgttcatttc ggttttcccg agcttattgc tgatgaaaga agaatagtga
     2281 aagaagatga acgtcatcgc gatgacggct gcaatgccga taagcacgct gatgtaatgg
     2341 aagatgccgc cctggccggc cgacagactc atcaccgtcg cgatcgtacc gggaccggcg
     2401 ataatcggaa tcgacaaagg cgtcacggat atatcggctt tctccttgct ctcccctttc
     2461 tcttcatgat ggagagactg tacatgagat ttcttcgcgt tcagaagatt ataagcgatg
     2521 ccgaaaataa aaatgccgcc cgcaatacgt aaggcatgaa tgttaatgtc aaacagttta
     2581 aagatcagat ggccgaagat taaaaaagcc gccaagatga taaacgacag cacggaagcc
     2641 ttgcgcgcaa tcgctgtccg ttctttctcc gaataccctt ccgtcagtga aagaaaaatc
     2701 ggcacgtttc cgatgggatt ggagactgca aacagtgaaa tgaagacatg aatgatgaat
     2761 gaaaacatgc gtacctcctt atggcttgcc gttattgagt tatgttttgt tctccgctgt
     2821 ttcttatgca tggtttttac cccggggtct gctttttata acctcagccg gacgatccgg
     2881 aaacagaaaa aaaccgtcct tgtaaggacg gtttttttgt ttgctatctc cataagcctt
     2941 ttccgaattt caacagccga taaagcattt tcaatttttt tagcatgcgt taatttcctt
     3001 tttcactctg aatcaatgcg ccgagagaca tgatatctat cagctccatt aaaattctac
     3061 cataatgggt actttttctc tattatcaat tcatagagaa agtgatttgt atatctttag
     3121 aaaactccgt tacatccgcc ctattttctt ttataatgta aatattgaac aaaatcccta
     3181 tattacttgt aaaaggagtt ttagaatgta ttgttctcaa tgcggccatc atactgatgg
     3241 cggaaagttt tgtgaaaagt gcggggcgcc ccagcccggg cagggaggcg caggccaaac
     3301 gcagggccag gccgctcaga ccggcgccgc ggctaagcag gcttcaaagc aatttgcctt
     3361 attcgtgctt gatgtgttaa agagaccgta ccaaacatgt aaaacgacag gcggcgaaca
     3421 gcttgtcagc agcatcatca acatggtgct tttctgcctg gtgacgccga ttatgtttta
     3481 tattctccta tcagacggct ttcgtgacgt cagttttacc gcagttgtga tcaagccggc
     3541 gcttaccttt gcattaagcg ttttctgcct gtatctcttg atttttatcg ctttgaaggc
     3601 cggcggcgcg caggtgtcat ttaaagattc gctgtccaga ttcggggcct ttttgattcc
     3661 gtttacagct attttgcttc ttgccctcat ttttatgctg cttcatacaa ccgtttgctt
     3721 caccattctg gctgtcggtc ttttaggagc ggcgtttgcc gtgcctccgc tcatgctggc
     3781 gagctatcag catcagctca ctcctaaggc ggatatcatt tattctgtta tcgtcatcta
     3841 tttgatcatt tgcgtaacgt ttcaattcac gatcaagcat tatataaaag aactcatgaa
     3901 ttatttcttc ttttaaaaac ggaaaccccc gccgcctgat tggcgcgggg gtttttttta
     3961 ttgaatggat gttaaataaa ttcttccgtc tttaacaacg ccgccatacg tccaattgta
     4021 tgttctgagc ttcggactgc cgccggcttt cgtaatataa aactcctcgt acgtgtgaat
     4081 cgtcaaatgg gagcctttct gtgaaaagct tttgacattc acttcattaa atacttcggt
     4141 cgtcccctcg ctgtgcagtt ttttgaccag tttctgctga tcagcataca aagggctccc
     4201 ctcttctaaa ttgcccgcca tgatggcaaa attgttaagg ctgacggcgc ttgattgatt
     4261 tgtcaggtaa tcagtcataa acgttgtgac ttgctcgttt gtcacgctgc ctgaagctgt
     4321 gtttcctttg gaagatgccc atgctgatgt ataggttttc ggctggtcgt tttttatttt
     4381 ttttacattt gtcccagaag aatctgaggc tggatcagct ttttcaaaaa cccatttttt
     4441 atgttttgta tcatatgaga gtacataatg aaagctcggc tcagcctctt ccatatcagg
     4501 cttcgtattc ccgtcgaaat aagcagactc atgaagctct ttacccgtaa cagttacttg
     4561 ccagcggccg ttctcttgag aaatcgcaaa tgaatccaga tcaaagcttg tctctttata
     4621 ctgatccttc aaaaaggtgc cggaactctt catgccggat accgcttctt tcgtctgctc
     4681 tttccagacg gaaccagcct cggtcatctg atcggtattt ccgtctgcca tcgcttttgt
     4741 atactgcttc gttgttttga caatcgtgtc catgattgtt tgttgtgtat cttgatccgg
     4801 gataagcgtt aagtccacat cagtactgtt gatcggaaca tcggcagttt tcattttccc
     4861 ccaaggaaaa tcagcctcca cggcggctgt catggaaccg tcagttaaga gcggaccgta
     4921 tgtaacggat gtaaacggat ctttatggac ggacttgccg tttatcagca gatcgccttt
     4981 cgcgcttttg aagctgtctg ccggagtgaa tgtcacatcc tcggcgtcta acggcaggtc
     5041 aaactcaaca ttccggctgc cggccgcctc tgcctcttgc tttttgacaa cgtcaaccgt
     5101 ctcattttta agcttggctt ccgccgtgta gacaccgggt gcatacgggc cgaagatttg
     5161 ggtttcatcg gcttttttga ccgtacctgt tttctcgctg ttaatataaa gatcggcgcc
     5221 tttataattg cttgtgacgc ggaaataaac cggatcgact ttcagttcgt aatggtcaaa
     5281 caaaagaagg gtttttccct cttttttgac gtataccgca tctttttctg atgaattgcc
     5341 gcgaagcgat gccagcagtt catcgtgttt ctttgcgtat gcaaggagcg gtttgacatt
     5401 ggtctcattc agcttcagtt ttttgtctga aggagtgagc agggctgcga gctttttcgt
     5461 gtccccgtca tgaaccgcct gttcgaattg atctgtgagc cttttttcag atgtcagcca
     5521 ggctccggtt ttatatgcgg caatcaataa gatcagcgct gcggcaatgc cgccccatag
     5581 gaagagcgtt tttttaggga tcggctttct cggctgtgat gcggattcag ccgcctgccg
     5641 ctccagccgg cttcctttcc cgatcggttt tccgcattct ttacagaaat gcgcctcttc
     5701 gttgttctgc tggccgcaat acttacaaaa aaacatgact ttcctcctat tcaatctgca
     5761 aaacttgtat aacttttcct atgtttcata ttttataata aagcagaatg attttggagt
     5821 tattttgaaa aatagctgtc gatcataacg gaggaggaga aacggacatg caaaaactga
     5881 gcatccgaaa agccgcggag ccggatgaag cgctgtacga actattgctg ctggccgatc
     5941 cgtcgaaaga gattgttgat gattatcttg taagaggaga atgctatacg gcttggacgt
     6001 cagacgagct tgcaggggtc ttcgtccttt tgaaaacaag accaaaaaca gtagaaatcg
     6061 tcaatattgc ggtgaaagaa tcaatgcaga acaatggcat cggcagaaag ctcatagaag
     6121 aggccgtgaa taaggcaaaa caaatgggag cggcgactat tgaaattgga acgggcaact
     6181 ccagtatagg ccagcttgcc ctttaccaaa aatgcggctt cagacttcaa gccatcgacc
     6241 atgatttttt catcaggcat tatgaagagg agattttcga aaacgggata cagtgccggg
     6301 atatgatacg gctttatttg gacctttaat aaaagaactg ccaatgatgc gattaaaccc
     6361 cgttttcgag acagggataa aaacactttt aaacagccaa ttgccgctcg tctatcaatg
     6421 attggctgtt tagttcgttt gaatacgaat attgttatta taaatgtaat cgttgacagt
     6481 gcattctacg atgacgggcg tggttttgtt ttaacagctt ttctgacact atgcaacacg
     6541 cagctctcag gcagaattgg cagctgatca agtgtgtgtc ctgtttatct ccaatcgtaa
     6601 aagcattcac ttctccattg tatacttcca atatcgcgaa cagatacaat tattctgact
     6661 ataaggaaaa ttcgggaagt ctgttactat tttttcaaga gggagatcag gctgaaagtt
     6721 ccatattatc agctacggca taaatatgct catttttctt gcatccttaa tccggtactg
     6781 ctactcattt ttctgaatga tacgctgaaa cgttttatgg ttaacacgca tttccttttt
     6841 tattagggaa gtgatgatcc aatagcccta tcgataccca tgctttcggc ataatgcgcc
     6901 aatgtgtttt tccaaatgcc ctttgcactg attcttcttc acatttttct ttcagagaca
     6961 ataagacgct cgtgagatac ctaaaagatc acagatatct gcaaaacctt ctacaagtcc
     7021 gactgaagtt tggctattaa cttcctttct aattcgttgt actcttttaa cacttcattc
     7081 ggctgtcgca aataacgatt ctctgcctgc agtctctggt tcggaagtaa accccagacc
     7141 atttccgtaa gtatattgct tttcaacagg ctgttcgaat gtatatcccc agctttatgc
     7201 tatctaatcc aagtctgcac gtccgtgtat tcttaatatt taatttctgc atcatctctt
     7261 tcatcggcac gcctgccaat ctcatgtcta caccttctgt ttgacttcaa ccggatcact
     7321 tactcttatt ccatagaaaa aacacctcca agtctaatac cggataacag tcatccgttt
     7381 tcaaacttga aagtgttttt tttttggctc atcttatagg tcagtccctt tgttttttct
     7441 aaagacataa agttgcaatc ttttgttggt aggaacatca agtaatagat taaaacttaa
     7501 taatccataa aactcttatg ttctttatac cattctaatt ttaaattcat taaaataatt
     7561 ttaaagttta acacaaattt ctcagttgct gcccaaagga ataaaatctc ctcattgatc
     7621 ttgatgttta agatataatt atacttattt attattattt ttgtatctag cataaaaata
     7681 aaggtcaatt aacgatccaa tcaatattcc tatggaaaga ccatacggta aaatatcaaa
     7741 aacaactcct aaaaaaagac ctaaacaaaa acctattact agaaataccg ctccatctcc
     7801 tttatagttt ttcaaatcaa acaactcctt aatagtgatt atgatgaata tgttttttgt
     7861 tttttcgttt gtgaacgata tagattacta tatacccctt ctaaagcaat cagttcttca
     7921 tgtttaccaa cctccaccac ttcaccttta tctaggacaa ttataaaatc cgaatccata
     7981 attgttgaca atctatgcgc gataaccact cttgtgcatc ccatttcact taaatattta
     8041 gaaatcaatg tttcattcac caaatctaat gaacttgtag cctcatctaa aattaaaatt
     8101 ttagggtcat ttaaaagtgc tctggctagt acaatccttt gtcgctggcc acctgataaa
     8161 ttcataccca tttctgaaat aggtgtatta tatttcattg gcatactttc aatttcttta
     8221 tctatttgtg ctgctttcgc tacttttctc actttttcta tactaatatt tttattattc
     8281 aatgtgatat ttttcagtat agaactatta aacaaggtaa tatcctgggg tacaattccc
     8341 atttgtttgt ataactgttt tctatctaat ttttcaagag ggatactatc aaaacaaatt
     8401 tgtccttcag tcggatcata aagccccatt attaacttac taagtgtact tttaccagaa
     8461 ccagatgaac ctactatagc aattttctgc ccttctctta tttccaaaga aatattctta
     8521 agcacctttg gagaatgttt agtataagaa aaagagacgt tttcaagctt tacatttcct
     8581 cttaatttaa ggtttactgc attttcaata tttttttcac attcagtctc tgtaatatct
     8641 ttaactcttt ctaagtaaga agtagctaag ataaactgag tataagtacc aaataaagca
     8701 gttgttaatc caaaaaaagt aacagataaa gaatgatatg cgataacctc tcccattgta
     8761 aatttattat caaaaaataa tagcagttct aatattaaaa taaccaaggg agcaattgtt
     8821 tgaaaaacct gagttactgt attaactaca ttttgtaaaa tggatctttt tttgaatcgc
     8881 tttattactt cattaaaact gttattccaa gttgagaaaa tttcattttc cattcccgaa
     8941 attttaatgg ctgcgataga aaaaatagac tcgatttgaa tggcttgaga tttactttgc
     9001 tcagctactt catcatcgat ggcctgcgcg acagcaggtc tagtcaaaaa catgaatata
     9061 gtgttaattg caaatattaa tattgttatc aaggttaatg gtatagattt aaagaacata
     9121 tacgctaaaa taaaaactac cgctcctaaa tcaattaggc cagaaattag ttgagttgat
     9181 aaaagctctc tgaatccatt catgctattt aacctaaata acaagtcacc aggtgatcta
     9241 agatcaaaga atttaaaagg aagttttaga agatgagcaa atgtatcaac aacaagattt
     9301 ttactaagga atatattgag gcttatcatt ttgagccctc taaacaaaac aaacattcca
     9361 tacaatattg atattaaaaa tgttatccaa acaatattac ttattgaatt taaattatta
     9421 tactcaatac ttgtatctat aagcttctgt accaaaatag gtacatacaa cgtcaataaa
     9481 taacttatta gagaaaaaaa tactataata gaaaataaca atttatagtt tgtaatattt
     9541 tttaatacac caaaccatac attcttatct tttcgtttat tgggagtgaa actttctgaa
     9601 ggaactgcat ataaaatata ggacgagaaa cctttcttaa actcttcttc tgttaatttt
     9661 cttcgtccat tagccggatc tataatataa taataatttt cctttatttt ttcaacgact
     9721 ataaaatgtt cattattcca atatgcaata aaaggaacat taattttttt taaccctaga
     9781 atagtggatt tatatatatc cgccttaaat cctttatgaa ctaataagtt ttttaactgc
     9841 ttaatagtaa gtccgtctct tccagcctcc aaaaatgacc ttaactcaaa aagagtttcg
     9901 ttactgttat aaaaacggat caacatagca caacagcaaa gtccacattc agtttgttgc
     9961 aattgtttta caataggtac tctctttttt ttcttcacta tcattcattg taactcctta
    10021 cttccattgc taacaatgaa ggattgacag gattgtgtaa ccttaataag ctgtagccta
    10081 cgcctccaag tcccagcata aatgtattta aatcaaaatg atcctgtaaa cctggaataa
    10141 aacctttatt tctaatataa ttaattgcat tttgagcttc tttaaatgct acttcctgaa
    10201 gatcaatatc attgagaagt tcacttaatt tcaataatat atctatatta ccaaaaatac
    10261 catgacataa gctatgatca gttgtttttt taaatccatc ggaaaggagc ttgcttatag
    10321 cgcaatttaa atctttatca acttctttat caacttcttt atcaactacg ttctctttgt
    10381 tctttaacag attttttaaa aaagctcttg atagagctat acctcccgca ccatgacacc
    10441 aatatactgg atcagagttc ccctctcctt ctcttaagtc cttccaatta gaggtattca
    10501 aatcaaaaaa cttattttct cttttcaata actcttttcc taaagttgtg tatttttcgt
    10561 ctttagtaat gtgacccaga taacaaagag cccacgtaaa accagaatat ccatgtgaaa
    10621 gtcctgttag ataattatat ttaccattct tttctaagca ttgatataaa gtattaccta
    10681 gtttacaaca cacggagttt aaaatatcta atttagtttc cttatatagg tttaataaaa
    10741 aaacaataag actagatact ccccctacaa tatccaatgg tatatctcct gaaatattca
    10801 tttcatttat tttattaata tattttttaa atttttcata gtatttataa tcatttgtat
    10861 aagtgtatag gtggtaatat atataggcta aggaacctat ccctgtaaat aatgataacc
    10921 ggccatccat cttatcatca ctcaaaaaaa gttcttcaat acctctcatt cctgcaaagg
    10981 ctaaatcaaa gtactcttta ttaccagttt cttttccaag taaagctaag aataatatta
    11041 ctcctccacc ttcatataag tcaaagttca atggacccaa ttttacttta ttattctcag
    11101 atattatagg tgttacccaa gtacatttgc ttctatcatt attccatatt gctgtttcta
    11161 aaaataagtc tcctatttct gttgcacact ctaaataatt tttattatta tttccaaata
    11221 atttaggacg atatttctta ttgtgtttgt ttgttctttt ccaactgtct tttatagttg
    11281 tagtaagtga cattcgaata taatattgct gtttttttaa acttgtttta cttatacttt
    11341 taattttgtt taatacaaca tcaagtaaac actctctaaa aaaatttact atacttgtac
    11401 ttttattaca aatcaaatcc aaagaattat acattgttga aaaatacgga acatcattac
    11461 acattaaaga ttccaactca tttaaattct tcttgctaaa tttatctgtt actccttccg
    11521 caatatttat ttttttaaat aattcctttc tttcctcaaa actagataaa taatttggat
    11581 gagtggaagc ttctaaaaac cttgcatata tactggtagc tcttaaaact tgccttactt
    11641 ccaggttgct gcttcctact gtttttacca aatcataaaa accactttta ttttctaaaa
    11701 caaaattata acaatctgta aaacctttta atatttcttc aatataatct ttagggtctg
    11761 cggctttccc attatatgca gctctgtttt gagtactgtt cattattact gattttttag
    11821 ttaactgaat ttcatcagtt ccttcgaaat ctataatata cgatttccat atttctgatg
    11881 tttgattttc atcatttgat attccgccaa ggtcaaaatc aaatatagaa gtttgtaaat
    11941 ttaatgggag aagcatagtg ccaagaactg agtaattaat atcctcatga aaattatcaa
    12001 ttaaattatt atttcttggt ttatacatag aattattttt tatcagagtc tccaagtcaa
    12061 taacaacagg atattcgcca tgtgcaatta agttttcatg atgcaaatca tcgcatccta
    12121 taatgtgaaa aatagataaa cttacaccta ctctataaaa atagaagttc agtttttcgg
    12181 aagtctcaca ttctttataa tcaataaact cttgatagcc atagtcttta taattaagcg
    12241 ttttaatttt ataaattttt tttagaattt tatctgaatt attaacatag tcaactatac
    12301 tattaaataa gatatcagga gataaactat gcggcttata tacaattttc ccttggtttg
    12361 tttcaattat taagacattt ttccctccat tatgagtgtc tccgctgcta aaataaatat
    12421 tggagacttc atcaaattca atttttagtt ctctataaat gtcttgacga ttttttctta
    12481 aattctctag aacttctttc aagtacaaga ttttatttga tattctacta gaaattaaat
    12541 aggttaaaac aggatactta ttcaaaattc cagccacata ttcactctta aaaattaaat
    12601 tattataatt cttatagcgt aaccttgaat cttttccttc taataaacca ttttcttttc
    12661 tttcattaat atcaacgatt aaagttctta tacataactg aattaattcc tggctaaaag
    12721 cctctaacgc actacttata attttatgtt tgttaagttt taaattattt tccttacttg
    12781 cgttttctaa agtattaact aatttttgtt gataaaaatc taaaaagaat gtataaaagt
    12841 tgccaaagta atctttgttt tttattctta atttttctac ttcgtttgtc ggcgaactga
    12901 aattaattac agcatctctg atgaaattat tgttttcata gctaatatcc atttataacc
    12961 tctccaaaag atttaataga gaattgtttg ttaaaacaat tctctattaa cacattatgt
    13021 ttatttgtta cactgttttg tacacgctga tgttggacat gatgctgcac ttaaagtaac
    13081 tgtaaaagtc gttccagtga gtccaatagt tgcagttaaa acgactgttg gagtagctcc
    13141 tccagtagca ttatcaccat tagctaatga tataagttcg tcttcttcaa taaaacctga
    13201 agcctttttg accatatctt tcttcataat tctctcacct cctttcaagt atgactttga
    13261 ataagagtgt taaagcttat tctagccata aaaaattagg aacaatttcc ggagcataat
    13321 ttttgatcat tgagtaacct attcctgata atccgatcat taaactatat gatctagtac
    13381 agactaagtc tctctttctc catttcttgg tcaaaacatt ttcaaatagg tcttgataag
    13441 ttcttaaaca tctattcttc aaattaatat tgttagttaa atcagaagca taattcaata
    13501 tagaaagcac acctaaatct ccatgacaat atgtagggtt attgccaatg ccattacgaa
    13561 tagaagaatc tattgcagtc gatatttctt tttcaatgta ctcgtcttca aaaccattat
    13621 cttttaaaat caatttactt aaaagtatac ctggagctcc gtgacaccat ccattagcta
    13681 acttatcttt attttctgtg gtataccaat tattgtggtc ttcagagtac aatctccttt
    13741 caaatcttaa ggccctttga atgacttcca ataatttttc atcatttgtt aacttaaaat
    13801 atttatataa gtatgcgata aaaccagaat tgccatggga aaaccctgaa tatgctgctg
    13861 aaaatttccc tggccacgat atttgctcct caaaattttt tgctacactt aatatatgat
    13921 cacaatgagt atgtgaaatc tttaaaattt cctttttgtt attctcttca gtaatatctg
    13981 gtattatgga aagcataact gctaaactac ctaaagaccc tcctattaaa tcgtatactt
    14041 tatcgaattt acctaacttc gataaaacac cgatgttttc aaacgaggtc ttccttaatt
    14101 ctgaatctcc aaataaatta gataacttat ttaatgtata aaaatatcct gatatacctt
    14161 gaaatgcacc tattaaatat gggtgatctt cttttatttc agagataaac ttctgtattg
    14221 gtctcatagt ttcgatagct gcttgcttaa aatcctttct gttgaggatt tcgcccaagt
    14281 accctaaaaa tagagcaatc cctgaattac cattatatat atcgaatccc aatacatttg
    14341 cattccaaat gtcttcctca ataccctcaa gactaggacc tatccacatt ctatcttttt
    14401 gttttttatt tataccacat acactgtttt caactataaa ttcgcctatc tcggttgctt
    14461 catctatcca attttctgac ttaattttat ttaagcttgc agctttagag aatcttatat
    14521 cagtaacttc tttcaatctt ttttcattac taatgtaaga catttcaata aaatcaatct
    14581 gtcttttcaa atcttctttc gaaagattaa aaatcttttg ctttactgtc tttattggag
    14641 gttcttccag aatgctgtga attcttttcc ctctagaatc tattaaatgt tcatgttcaa
    14701 tagaggatct aaaaaatgga acgtccccag ttaataaatc tttatattct gagttcaata
    14761 tatctttata ctcttgtata taatcaatgc cgattctatg taaaataatc ttacgtctat
    14821 aggtatctct cataaaatct ggatgacttg agattcttaa aagctgagtg tataagtaag
    14881 tgggtctgaa gataaacctg ctatttgttt ctttaaaagt ttgagaaatt ttatcccaga
    14941 attcatcttt atttaacatc acccaactat ataaacttgc aaaaccatct ttaatttgtc
    15001 ccgtataatt ttctgaatat aagtaagacc ctgttttaat ggaagggttg tttaattgag
    15061 gtttaatgaa agtatttttt cttaaaattt taatcgtatc tgttcctgca ttttcaatta
    15121 ctaatgattt atgaggagag agttgttcct tataggcagc taatccccct atatctagac
    15181 ttatgtcttt gtctcctact ctcttagaaa tttttgtagg caataaactt attgactgta
    15241 cagagttatc aactaattca gttgctttaa caacagctga ctttttatca atttggtcaa
    15301 cctttagtct tgcatgaaat aatgattcta agtcaactaa tactgggaaa gaaccatggg
    15361 ctattaaatt ttcatgatga aaatctactg catttagaag atacagtaaa caaagaagat
    15421 tacctgaacg agtataaaaa tcatttgctt cgtttttatt aaaacaactt ttataatcta
    15481 tgtgctccat ccaacctgaa tcatttactg tatgtatttg aactcttttg aaatttaaaa
    15541 ttcccggtat gtttttctcg cccaaccaat ataatacttc ctggaaacct tgttcaagcg
    15601 ttaaatctct gggtttataa attattttct tgccactttt aaaatatatt gttgaaacag
    15661 attttccttt ttgatgagta tctcctagac cggtggttat atttgttatt gcacctaaat
    15721 cgttatcaga gttgaattta gagtttaatg aactaatttc tcgttttgtg ttttttatta
    15781 tttccattac atatgtgaaa taatcatcaa tcgttacaca taataaactt gttaatactt
    15841 catattcttt ataaacactt tttaaaaatg attcatcatt taaagataca actaaaaaat
    15901 gatttagtct ttcttccggg gtagtcccct ctaaattccc ctctaatctt gcaatattca
    15961 cttccaaaac aagaacccta aaagcttttt caaacattaa atccattata tgtttaatta
    16021 cctttttcac aaattcatcc tcattatcta ctgcatcttc aattcttact tttactaaga
    16081 attcttcaat tttgcagtta agaaaaggag aaaaaaaatg aaaaaatgga ttatgctcta
    16141 aaaattcttc agaatttctc actaaaaaat cacttttttt atgatctaag actctatcaa
    16201 tatctataat acttttattt tgctcaatat tagtatcgtc tctaattaat gattgaatcg
    16261 tcttaccaga tacatttaaa aaaatctttt gcaattcatc tttattgtta acctcaggaa
    16321 acattttcat ccagtattgg agattatatt tgttagtttt caaagttaat gatcctacct
    16381 taatatattt tttgcaaaat aggcagttaa ttacactgcc tattttatac ttatttcagc
    16441 aagtaccttg acattcttta gtacctgtac aaactttgcc tttatttcca agaacctcac
    16501 ttactaaaat gccccccagg ctagtagttg ttgtattcca ggtattgaaa gctcctgaaa
    16561 cttcatgttc tttaatttct tcaagaacat ctccacatgg gtctatcaaa tttaaatctt
    16621 ttgtcacttt caattctggt gtttttaata tctttgtctt cttcatacta tctacctcct
    16681 cattttttac tggataaaat ctctattaac ctgttcaata ataatctacc atattttcct
    16741 atagtaaaca atgggtttta tgtaattttt ttattttatg agattctcgg ggggggtatt
    16801 ttatacttta ttttaacagg gcagtttttt ataataccaa aaagaagtcc tttgttttta
    16861 ggaatgtaat ttttaaaatg ctttaggaaa gaaataaaac ggttttcaca ttactgcatt
    16921 acaaatttta aaataaaaaa tatcgtaatc ctgccttttg caagtaaaag aacaacagtt
    16981 atgttacaca ggaactctta tttaaaggag agaatacttt cttttggagt tgtcatcaaa
    17041 attatttaga ttaataagga attaagtaac tattattttg ttctgagagg gcgtcaacac
    17101 aatcagctac taccttaact tttataagta ttatatgcag ctaaattccg ggcagctgta
    17161 gaccattgtt ttttatctag ggcacagcta atgactatcc gttctgtatc tgagatggct
    17221 gaattaagga tataagtatc tgtgatcaca agattgttta cttctcgttt taggaatatt
    17281 gaaagggtca gaccatgctt tgtcattaac taaatactag ttatactcac aaccttacat
    17341 taattgaatg ttttcattaa atttgaagaa gtgtccgagt tggtgagttt tattgagcgg
    17401 ataccatgat ccaatgtata cagttgttca aacatggttt atttttcaat acttctctcg
    17461 gggtctaaga gagttttctc ctgatgcagt aaccagattc ctactagata ccgggagttc
    17521 catatcataa aatgcaaatg ttatcatttc ttgtatgttt tcttgattcc aagcgtctgc
    17581 tattcgctaa accgacagtt actccgtaaa aagtaataac catcctcctg taagctttaa
    17641 agcttcactg ccctttttca agatcggcta gtgaaatttt tagcctcaga tattcgatcc
    17701 gagtaatatt agtaggtctg tactctcgaa catccattca tcaagggaga tatctggttt
    17761 tatgcgctaa gctcgagcgt agttatcatt tttttattca ccctattgtc atgactttta
    17821 aaagtgcggc atcttatttg aaactttgca agttcagttt gatcttaatt atccatattc
    17881 ccaacctaac attgtaggaa atgcgtaaag ataaactgat tttgatcatt caaacactcc
    17941 aactcaaaaa aaccctgact gctttgtcag ggtaatagaa attctagaaa ttcagctctc
    18001 ccacacttaa aagggcttgg ctgcagatgc agccaagccc tttttatgct tacttattca
    18061 agttatagaa agagttgata ccgtggtatt gagcagtttc agccaactga tcttcgatgc
    18121 gaagaagctg gttgtatttc gcaacacggt ccgtacggga cggagcacct gttttgattt
    18181 gtcctgcatt agttgccaca gcgatgtcag cgattgtgct gtcttcagtt tcacctgaac
    18241 ggtgagagat aacggcagtg tagcccgcgc gtttcgccat ttcgatcgca tcgaatgttt
    18301 cagtcaatgt accgatttgg tttactttga tcaggataga gttgcctacg ccgtttttga
    18361 taccttcagc aagctttttc gtgtttgtaa cgaaaaggtc gtcaccgaca agctgaactt
    18421 ttttgccaag acgctctgta agaagtttgt ggccttccca gtcgttctcg tcaagtccgt
    18481 cttcgataga gatgattggg tatttagaaa ccatttcttc gtaccagtca accatttcag
    18541 cagatgtttt cacaacgcct tcgccagaca gatggtattt gccgtcttct ttgttgtaga
    18601 actcagaaga tgcagcatcc atagcaagtt tcacttcttc gccaggtttg aagccggctt
    18661 tttcgattgc ttcaacgatt gtttgaagcg cttcttcgtt agaaccaagg ttcggagcga
    18721 atccgccttc gtcacctaca gctgtgttca ttcctttagc agaaagaact gatttcaggc
    18781 tgtggaagat ttgagcgccc atgcgaagcg cttcacggaa gttaggcgcg cctacaggca
    18841 taatcatgaa ttcttgaatg tctacgttgt tgtcagcatg ctctccgccg tttacgatgt
    18901 tcatcatcgg tacaggaagc gtttttgagt tgaatcctcc aaggtattgg taaagaggaa
    18961 tctgtaagaa atcagcagct gcgcgcgcac aagccataga tacgccaagg attgcgttcg
    19021 caccgagttt gcctttgttt tcagttccgt caagctcgat taaaagctga tcgattgcgt
    19081 tttgttcagt tacgtcaaag ccgagaagct ctggagaaat gatttcgttt acgttgttaa
    19141 cagcagttaa cacgcctttt ccaaggtaac ggtctttgtc gccgtcacga agctcaaccg
    19201 cttcgtattc acctgtagaa gctccgcttg gcactaatgc gcggccgaaa gctcctgttt
    19261 ctgtatatac ttcaacttca actgttgggt tgccgcggga gtcgaggact tcgcgtgcat
    19321 aaacatcaac aatgtatggc atgagtttgt ctctcctttt gatttacgct tatttttgaa
    19381 ttaaagatgt tcctgtcatt tctttcggtt tttcaacacc gagaaggtct aataacgttg
    19441 gtgcgaggtc gcctaggatt ccgccttcgc gcagcgtcac gccttctttc gtcacaatga
    19501 cagggactgg gtttgtcgta tgggcagtgt gcggttcgcc tgtttctgta atcagaatgt
    19561 ccgcattacc gtgatcagcg gtaatgatgg catgtccgcc tttagcgatg atggcgtcaa
    19621 ccacttcgcc taagcattcg tccactgctt caattgcttt aatcgtcggt tcgaccattc
    19681 cggagtggcc gaccatgtca gggtttgcaa agttcaggat gatcgcgtcg tgcttgtcag
    19741 ccgcgatttc ttttacaaga gcatccttca cttcatacgc gctcatttca ggcttcaggt
    19801 catatgtcgc gaccttcggc gagttaatga ggatgcgctc ttcgcccggg aattcttctt
    19861 cgcggccgcc gctcataaag aacgtaacgt gcggatactt ttcagtttct gcaatgcgaa
    19921 gctgttttaa cccgtgctgt gctaatactt cacccaccgt attgtcaagg tttaccggtt
    19981 taaaagccac atatccgtca acagattcac tgaagtgagt caggcagacg aaatacaggt
    20041 ttttcggatg attttcaccg cggtcgaaat cgcggaaatc tttgttggta aacgtgtttg
    20101 aaatctggat agcgcggtcc ggtctgaaat tatagaaaat cacagaatcg ccgtcatgaa
    20161 ttttcgcaac gggttcaccg ttttcttttg tgatgacgga cggaatgacg aattcatcat
    20221 gaatgccgtt cgcataagaa tcatcgacta catccatcgc gctgcggtaa gacgggcctt
    20281 cgccgtaagc cattgcgcgg tacgcttttt ccacacggtc ccagcgtttg tcgcggtcca
    20341 tggagtagta gcgtccggaa atgctggcga tttcgccgac accgatttct tcgatctgct
    20401 cattcagctg ctgaatgtaa gttttcgctg tttgcggacc tacatcgcgg ccgtcgagga
    20461 aaccgtgaat atacaccttc gtcagtcctt cacttttcgc aagcttcagc agcgcgaata
    20521 aatgattgat atgactgtgt acgcctccgt cagaaagaag gccgaacagg tgcagcgctt
    20581 tgtcgttgtc tttcgcgttt ttgatggcgt caaggaacgt ttgattgcgt tcgaattcgc
    20641 cttcgcggat ggcaacgttc acgcgtgtta agctttggta cacaatacgt cctgcgccga
    20701 tattcaaatg accgacttca gagttcccca tctgtccttc aggcagtccg actgcttcgc
    20761 ctgatgccgt cagcgtctga tgagggtatt ggttccaata acggtcgaaa ttcggttttt
    20821 tcgcttgtgc gactgcgttt ccgactgttt cattgcgtaa tccgaaccca tcaagaatga
    20881 tgagtgcagc tggtttttta ctcatattga ccttcctcca ataattgaac gaatgactgc
    20941 ggttcaaggc ttgcgccgcc gaccaaagca ccgtcaatat cggactctgc catatattct
    21001 ttaatatttg caggttttac gctgccgccg tattgaatgc ggagcttgtc agcagtttcc
    21061 tggctgaagc tttcagcaac gactttacgg atatgcgcgc agacgtcgtt agcatctttc
    21121 gctgtagaag atttgcctgt tccgattgcc cagattggct cgtacgcaat aacggaagcg
    21181 gcaacttgct cttcagaaag acccgcaaga ccttttttca cttgatcggc aacaagatca
    21241 tttgtttttc cggcttcgcg ctcttcaagc gtttcaccta cgcaaatgat cggcacaatg
    21301 ccgtgtttga aagcggcatg cgcttttttg ttaactgttt catcagtttc agcgaacatt
    21361 tcacggcgct cagagtggcc gatgacgcag taatccacgc caaggtcttt cagagcgacc
    21421 gggctgattt cacctgtgaa cgcaccgttt tcttcaaaat gcatgttttg ggcgccgact
    21481 ttcaggtcag ttcctttaac agcagaagtc agcttttcta agaaaagagc tggtgcgcaa
    21541 acaacggctt ccgctttgtc tgctgctgga atggaagatt tcacttcttc aacgaagctg
    21601 acagcctcgc cgagtgtttt gttcattttc cagttaccgg ctataattgg ttttctcatc
    21661 tgttccactt ccttatagca gtttttattt atcgttcagc gcagctacac ccggaagctc
    21721 tttgccttcc atgaattcaa gggatgcgcc gccgcctgtt gagatatggc tcattttgtc
    21781 agcaaggccg aatttttcaa cggctgccgc agagtctcct ccgccgatga cagagtatgt
    21841 atcgtttgcc tctgccaatg cttcagccac tgcttttgtg ccttgagcga acaagtcgat
    21901 ttcgaatacg cccatcggtc cgttccatac gacaagtttg ctgtttttga taacttcagc
    21961 atacgtttcg cgggttttcg ttccgatgtc gatcgcttct aaatcacttg gaatctcaga
    22021 gatcggcacg atttgaacgt ttgcatcgtt agagaaatca tcagcaacga gcacgtcttc
    22081 cggcatatag aatttaacgc ctttttcttt cgcgcggtcc atgaatgatt ttgcaagttc
    22141 gattttatct tcttcaagca aagatttacc gacttcatag ccaagcgctt ttacgaatgt
    22201 gtaagcaaga cctccgccga tgatcaggtt gtccacttta tcaagcagac tttcgattac
    22261 gccgattttg tcttttactt tcgcgccgcc gatgattgcc gtaaacgggc gctcaggatt
    22321 tgtcacggct ttgccgagaa cgtcaagctc tttttccatc aggaatcctg caaccgccgg
    22381 cagatgctcg gcaattccgg ctgtagatgc gtgagcacgg tgggcagcac cgaatgcgtc
    22441 attgacatat acatccgcaa gctcagcaaa tgctttagca agctcaggat cgtttttctc
    22501 ttcaccaggg tagaaacgta cgttttccaa tacaagaacg tctccgtcct tcatatcaga
    22561 aatttgtgct tttacagcat cgccgtaagc ttcatccgct tttttcactt ctttgccgag
    22621 cagttcgcct aagcgtgcag cgacaggagt taaacgaagc tcctcaaccg tttcgccttt
    22681 cgggcggcct aagtggctcg caagaaggac tttcgcgcct tggtctgcaa ggtgtttgat
    22741 tgttggaagc gcagcgcgga tacgagtatc gtctgttact tccccgtctt tcattggaac
    22801 gttaaagtca acgcggcaga atacgacttt gccttttacg tcgatgtctt ttactgtttt
    22861 tttattcatg ccttaggaga tcctccttca aaatggtttg catagcacga aaaacgtgaa
    22921 acgtgaaacc acctcatgat gcttccgccg cggggcagat tgcagcttcc gggcacgggg
    22981 cagatcgtct tctgagccag ggcaggcggc tcagaaaacg aaagtgccgc ggaaacttca
    23041 aaacgcggac gttctgcagc aatccggcgc tttctgaaag ccggttctca tggaaaaagg
    23101 gaaagggagt ccgtcccctt cccttgtccg ctttcattat agcgtttctg tccgaaagaa
    23161 ccaagtccgg ccctttccgg gagctatgaa ttaaagacct tgttttgcga tgtaagctgc
    23221 aaggtcaaca acgcggttag agtagccgct ttcgttatcg taccaagaga ttacttttac
    23281 catgctgcct tccataacca ttgtagaaag agcatcgatt gtagaagagt tagcattgcc
    23341 gttgtagtct ccggatacta atggctcttc gctgtagcca aggattcctt taagatcgcc
    23401 ttcagccgct tctttaagag ctgcgtttac gtcttcagcc gttacgtctt tgttaagttc
    23461 agcaactagg tcaacaagag aaacgtttgg agtcggcaca cgcatagctc cgccgttcag
    23521 tttgcctttc agttcaggaa gaacgaggga aactgcttta gcagcaccag ttgatgtagg
    23581 aatgatgttt tcagctgctg cacgcgcacg acggtagtct ttgtgcggaa gatcaagaat
    23641 ttgctgatcg tttgtgtaag agtgaacagt tgtcatcata ccgcgtttga tgccgaattt
    23701 gtcgttaagt acttttgcaa acggcgcaag gcagtttgtt gtgcaagatg cgttagagat
    23761 aacgtcgtgg ttagccgcat cgtatttgtc ttcgttaaca cccataacga ttgtgatatc
    23821 ttcttcgtta gcaggtgcag agatgatcac ttttttcgcg cctgcttcta agtgtttcgc
    23881 agcgtctgcg cgttttgtga agaaaccagt agattcaact acgatttcaa cgccttgttt
    23941 gccccagctg agtttcgcag gatcgcgctc agcagaaact tcgattgttt tgccgttaac
    24001 aacaaggttg ctgccgtcaa ctttaacttc tgcatctaat tttccgtgta cggaatcata
    24061 ttgtaaaaga tgagcaagca tgttagcgtc tgttaaatcg ttaaccgcta ctacctcaac
    24121 ttcaggattg tttaatgctg cgcggaatac gttacgtcca atacgaccaa aaccgttaat
    24181 accgactttt actgccatga ttatttcctc ctttaaataa gtgagagata tttatattga
    24241 gggactgtta tcccttaata acttctttgc ggctccttcg tccgtgacga gaaccgtgtt
    24301 tcgctgcttt ttaaaataag cttcgattgc ttctgctttt gatgatccgc ccgctaccgc
    24361 gataatgtcg ggaatggcat cgaggtcatc gagctgcatt ccgactgaat gcaccttgtg
    24421 aacgacttct ccgtccgcat taaagtagta gccgaatgcc tctgtcaccg catgattgtc
    24481 atctattttc ttcaaatctt ccaaaggcgt gtttcttcgc tccgccattg ttctagcttc
    24541 gccgattccg tgaacgagca tactcgctga tttaatcgtg tgaagcacct cttttacgga
    24601 aggctcttca ataatagatg agtaggcgcc ttgtgacagc tgcccgggaa cgaacaaaag
    24661 ccggtaagtg cctgaagcct tttccgccat atgcgcgcat atggtgttcg cctggttttt
    24721 cacatcttcg cctaaaccgc ctcttgcggg cacaaacagg agctcgcggt tttttgaatc
    24781 cggcgtcatc atatcggcga cggcttcaat tgtcgtaccg ccggttacag cgacgatatt
    24841 tttgcctgaa aatctctttt tcatacatgc aacggccgct ctccctaatt cttttttgac
    24901 ccaaggagat tggtcgctgt ctccggaaac gataatggcg tctttcagat taagccgctc
    24961 ttttaatgtc ttttccaaaa gcgtcaatcc taaaacatcc ttcatcgtat cttccagaat
    25021 cgaaagcagt gaatagccct cttccgtcat tgtcatgccg tttgttttaa tatcgatgag
    25081 attctgttct ttcaaaaact gaacctcgct tctgagaacg cgctcggtca atccgagact
    25141 ggctgcaaga cttctgcggc cgatcggttc ggtaagcctg atatactgca agatttcaaa
    25201 tcttttctgc atcacaagca aaagatcagg caataatttt ttttgagctt gtattaactg
    25261 gttcatgact caaacgttcc ttcctattca tactggacaa aaaatgtccc gctatgacaa
    25321 aaaacgtccc gtcatagcca aaaaaaatta tgtctgcttt ctttaattat tttaacagga
    25381 tgacattgtt aattcaactg ttaaaggtca attcctcgac attcttcgca gaatttacca
    25441 gtatctcctt gatacagtca ttatatacag aaacggaatg aaggtgacag acaaaagccc
    25501 gccggagcgg acttttgtcg taaaacgctt tcattttatc cagagttttt ctatttcttc
    25561 taatgattta tttttcgtct cagggcagat cgtcacgaca aacaagaaac agagaatatt
    25621 aatgacggcg aatatccaga aggtgtacgc gagccctaac ccgctgatca tcatcggcac
    25681 gaactggccg atcgcccagt tcgcccccca taagaatatc gtcgcaatac cggcggcgcg
    25741 tgcgcggagg tggttcggaa agatttccga aatcatgatc cacgtaatcg gcccgactga
    25801 cacgcagaaa gcggcgacga atcccaatat gatgacgact aaagccggac cgctcgccag
    25861 ctgaaaataa aaggatgccc cgattaagat catgaacagc gccataaagg ctgatccgac
    25921 ccccatcagc tttttccggc ctaccttatc gactaaaaga accgcgataa tggtgaaaat
    25981 cacttcaacg acaccgacga tgcatgtcgt gataaacccc gcattctgtc cgaagcccat
    26041 cattttgaaa atttccggcc cgtaatacgt aattgcgttc atgccgatga cctgattgaa
    26101 taaagccagc agaatcccga tcacaagcgc ttttctcagc cccggtttaa acagctgaga
    26161 caatgacccc attttttcta attgtaaaga cgtttcgatt tgtttgattt cttctttcgc
    26221 ggtctgctcg ccgttaatgc gcgtcagcac ggcgagggct tcattccggc gccccgcttt
    26281 cgcaagccag cgcgggcttt caggcacgat aagcagcacg ataaaaaaga tgacggacgg
    26341 aatcatgccg taagcgagca tcc
//
