LOCUS       NZ_JAABOK010000013     10828 bp    DNA     linear   CON 29-MAR-2024
DEFINITION  Chitinophaga solisilvae strain O9 NODE_13, whole genome shotgun
            sequence.
ACCESSION   NZ_JAABOK010000013
VERSION     NZ_JAABOK010000013.1
KEYWORDS    WGS; RefSeq.
SOURCE      Chitinophaga solisilvae
  ORGANISM  Chitinophaga solisilvae
            Bacteria; Bacteroidota; Chitinophagia; Chitinophagales;
            Chitinophagaceae; Chitinophaga.
REFERENCE   1  (bases 1 to 211789)
  AUTHORS   Jianli,Z. and Weiwei,P.
  TITLE     Chitinophaga flavus sp. nov., isolated from forest soil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 211789)
  AUTHORS   Jianli,Z. and Weiwei,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-JAN-2020) School of Life Science, Beijing Institute of
            Technology, 5 South Zhongguancun Street, Beijing 100081, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.5.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 246.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009928525.1-RS_2024_03_29
            Annotation Date                   :: 03/29/2024 05:41:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,090
            CDSs (total)                      :: 6,009
            Genes (coding)                    :: 6,004
            CDSs (with protein)               :: 6,004
            Genes (RNA)                       :: 81
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 16S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 0 of 5
            Pseudo Genes (incomplete)         :: 5 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:41:33
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 90919
            Orig. end                         :: 101747
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAABOK010000013.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..10828
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10828
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10828
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5828](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5828)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    159..170
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.16"
                     /tool="antismash"
     misc_feature    1355..1368
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 19.97"
                     /tool="antismash"
     misc_feature    complement(1355..1369)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 20.53"
                     /tool="antismash"
     misc_feature    1356..1369
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.21"
                     /tool="antismash"
     misc_feature    1356..1370
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 20.38"
                     /tool="antismash"
     misc_feature    complement(1360..1373)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 21.24"
                     /tool="antismash"
     misc_feature    complement(1360..1374)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.47"
                     /tool="antismash"
     gene            1606..2115
                     /locus_tag="GWG06_RS23930"
     CDS             1606..2115
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012301.4"
                     /locus_tag="GWG06_RS23930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator"
                     /protein_id="WP_160716523.1"
                     /transl_table=11
                     /translation="MAFITGIAFDGNLDKIKPLLTLYFIFMYSDVQILIVDDDPEDVFI
                     MQMMCKELSFLENVHFVPDGLTLLHYLDGLYENQLPLLIILDQNMPRFNGVQTLEAIRS
                     NTRYHLLRVIIYTDLPDALQSNRLKELGVEAFVTKPNTYEQGLEIMQQFHDCSKGGYTF
                     PMAATG"
     gene            complement(2116..2970)
                     /locus_tag="GWG06_RS23935"
     CDS             complement(2116..2970)
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014217997.1"
                     /locus_tag="GWG06_RS23935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_160716525.1"
                     /transl_table=11
                     /translation="MTRENIYQPFEIIYKEVDSCPVVPHQHTFFELIYIVEGSGIQYVN
                     GNSIRFETGHLFLLTPQDTHHFELDVRTRFFFLRFSQVYLNRQQTALMYTQDWRQRMEF
                     ILGNASHQPGCLLYAAADKQLVPALVDGLLKEDEGRQLYHGEVISQLVNTLITIVARNI
                     ALKLPEQVKDNTAVMALNLIRYIQEHIYSPQELRAEVVAKQFGISVSYLGRYFRKHTGE
                     NMQDYITNYKLKLVETRLQHSDMRINEIAAELNFTDESHLNRLFKKYRGMNPSAFRKQA
                     AVA"
     gene            3086..3904
                     /locus_tag="GWG06_RS23940"
     CDS             3086..3904
                     /EC_number="1.-.-.-"
                     /EC_number="1.6.99.-"
                     /GO_function="GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA]"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014573.4"
                     /locus_tag="GWG06_RS23940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="WP_127038006.1"
                     /transl_table=11
                     /translation="MKVLIVYAHPEPLSLNGSLKNSAVRILQENGHEVVVSDLYQMQWK
                     AAADENDFSSYTPGNRLFYSREAREALANGTLSAAVMTEQEKIRWADTILFVFPLWWFS
                     MPAIMKGWVDRVFSAGFAYGIKQRYGIGNLSGKKVMLMVTTGGMEENYLEKGGINGSMS
                     DLLFHIHHGICWFTGAASLPPFVVYSADRLTEDKYPAVETALEERLLTMDTTPVLPFRY
                     SNSGDYDEKDVLLPHLAAGKQGFALHLREELPLQEMIDTDTAAAIDEQRK"
     gene            complement(3842..4264)
                     /locus_tag="GWG06_RS23945"
     CDS             complement(3842..4264)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019301.4"
                     /locus_tag="GWG06_RS23945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DoxX family protein"
                     /protein_id="WP_127038008.1"
                     /transl_table=11
                     /translation="MRLYASFARRLSVLRDWPLLLIRLVLAYGFWHPAMMKWKDIHGIG
                     DWFAQLQIPLPYFNAYLVAVTELLGVVLLTLGLFVRFITIPLMISMVVAIITVHLANGF
                     EAGDNGFEIPLYYILFLFTLLVYGGGRISIDHFLER"
     gene            complement(4268..5017)
                     /locus_tag="GWG06_RS23950"
     CDS             complement(4268..5017)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021364.4"
                     /locus_tag="GWG06_RS23950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="putative DNA-binding domain-containing protein"
                     /protein_id="WP_160716527.1"
                     /transl_table=11
                     /translation="MNLLPDTYRIQQRFSAYCRSGNAVKLPGVTPGRLKHYRRLVFNVI
                     NDIMEDGFPVAFHHIPARKWNKMVKDFFTHHACQSYQVWKLPLEFYTYAVEQNWEEVYG
                     IPYLNDLLAFEWAETEVYNMEDIPAAPFQQGGNWLETPLVLNPEYRLLAFRYPVHLHGD
                     ATELVQGKGAWFVLLYRDPETGNVQFTDLSPWLAFVTEQLAVGITLKDILEYAPQLGIT
                     LTDTLERDTLAFLQQMQRQHFVLGFQS"
     gene            complement(5001..5828)
                     /locus_tag="GWG06_RS23955"
     CDS             complement(5001..5828)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008584484.1"
                     /locus_tag="GWG06_RS23955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_160716529.1"
                     /sec_met_domain="DUF692 (E-value: 4e-101, bitscore: 331.2,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVGVGFRRDFAADIISGKHITPDFIEFAPENWMHIGGNWKKILHQ
                     VVEKYPVLCHGLSLSVGSPEDLDRDFLRHVKQFLEDYRVQIYSEHLSYSKCDNAHMYDL
                     LPIPFRMDAVRHIAARIRQVQDFLQRPLVMEIVSYYTPVAAEMSEADFIGEVVRQSGCQ
                     LLLDVNNIYVNAFNHQYNAREFIQQLPLDKVAYIHMAGHTQVSQDLIIDTHGEPVIDPV
                     YDLFEWTIQYLKPVPVLLERDFNIPEMQELQQELNRLKTICQKQWTSQNELVA"
     gene            complement(5907..6260)
                     /locus_tag="GWG06_RS23960"
     CDS             complement(5907..6260)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GWG06_RS23960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_127038014.1"
                     /transl_table=11
                     /translation="MENNKSISKKMLLSGSLVAAAILGFAASQPASANPVSYHHMGTGE
                     AVRSALTGNGAAASAMELACGAKKDSAGVKKGKEGKCGEGKCGEGKCGTDKKKGEKKGG
                     KGHKPKSDTTKGA"
     gene            6596..7318
                     /locus_tag="GWG06_RS23965"
     CDS             6596..7318
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GWG06_RS23965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_127038016.1"
                     /transl_table=11
                     /translation="MKDKMPPVTSVYFTTLMKAYLRGTKTREEVLQDLYDAAHLQPADT
                     EDNEEDITRLILRTASAVNEDYYQEVIGSITQAPDAIPSRAGVIHQLEALLHGRITPEQ
                     LLQWATWHNDPGEDDGVSYFDDIAVDYFCTQLLPNPPEPFTPAHFEQALKIFTGNRNNP
                     LKDKVALVLLFDKERQRFLFYVGDYIQGHTAPEQLDVYLMNKFGMDHYSFPYMGTLSNI
                     MHDPAKLPALLHMAAYTE"
     gene            complement(7319..8179)
                     /locus_tag="GWG06_RS23970"
     CDS             complement(7319..8179)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GWG06_RS23970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_160716531.1"
                     /transl_table=11
                     /translation="MKKQALLFLACICCISAVQAQFLRKMKDRVRSLTAVRTDSSLTEG
                     PFETPANGPVNGQPSLTISGSGQLQLDSVFEFDIAVYQETEAWQGNQRVVKGGEEIIVF
                     YSSARPQLAVHLVSKSTGARYQFYADFRQGAQLSITAIHNIGSGTREKLDLHSMEPVYP
                     GETGYLNRLIKTGEKKVIAGVACEEYKADNIRRDSTIGGTSHALATASVWTPMQPHTLF
                     PGYALIPEEYKDEMERMLVAGSYPPVAMPLEMHLEYSNGDRVDTYTTDIVKNENRRVRV
                     AAVIE"
     gene            complement(8218..9201)
                     /locus_tag="GWG06_RS23975"
     CDS             complement(8218..9201)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018616511.1"
                     /locus_tag="GWG06_RS23975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl transferase"
                     /protein_id="WP_160716533.1"
                     /transl_table=11
                     /translation="MQVVSPEHIFSLQPDGLEAAALELFRYQYRENDIYRAYTDALHIN
                     PAGVKSILEIPYLPIQFFKTHRVACGDFEPELIFESSGTTQTVNSKHLVKDAAVYTQSF
                     MTAFEQFYGPVTDYVVVGLLPSYLERQHSSLVRMVQEMAVRSGREESGFYLYEHDKLFH
                     QLQALEARQQKVLLIGVTFGLLDFAEKYTMQLQHTIVMETGGMKGRREEWTREEVHAFL
                     KERLGVKEVHAEYGMTELLSQAYSKGHGFFETPAWMKILLRDENDPFQLTAGKGAGVMN
                     VIDLANIYSCAFIATEDIGKIHADGRFEVLGRLDNSALRGCSLMVS"
     gene            9352..9801
                     /locus_tag="GWG06_RS23980"
     CDS             9352..9801
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GWG06_RS23980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_127038022.1"
                     /transl_table=11
                     /translation="MKKTLFLFLAAGLIYACKKDNIGSKPMVSFKSYSADSITPETQQF
                     NVTLRVEDGDGDIEDSIWLAILIKSQQEVSKDTLWGKYKMPGIGQNRGNRIKADVILGL
                     QQEHFAFNYTARPNDSAHFVTYLRDSRGNISDTIATPIFPFRRNQ"
     misc_feature    complement(9802..9818)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 22.21"
                     /tool="antismash"
     misc_feature    9871..9885
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.06"
                     /tool="antismash"
ORIGIN
        1 ctgacagccg cctggatgcc gtcgcagaag gcatttctgt agaagaggtc atcccagttg
       61 gcgggcccga agtaacgcgg ctgtgaggag tctgccaggt agcgggggaa gttacgccac
      121 tgtgtttcat tggcgtattc ccggtaaaag ggcatccgga aatcgctttc atacttacca
      181 ttcaccacat cagccggtgg gcgcagcgcc agcccggcat aggcgttgac ggctacctgc
      241 attttaccaa cacgggggcc tctggtagtg atgctgacaa ccccgttggc cgccagcggg
      301 ccgtatctgg cagtagcgcc gaaatctttc agtacggaga tgctttcaat atcgttgatg
      361 tccagtcctg ccagggtatt ggtttctgtg cccatcctgt taaaatcaaa ccgttgtatg
      421 tcataggcat aagcgtgttc ctgaataagc ggcatgccat ctactacata aagcggttgt
      481 gcataaaaca gatcgctgtt tttcaggagc agggaggaag taccgcggat gaacatgctg
      541 ctgcgctttc ccggttcagc ggtaggaata cgtatatcca ctcccgttac cctgccaatg
      601 agcgcctgtt cgatggtgag ataaggtaat tttctgactt cgctgatgtg gaggtccgat
      661 gcggcgcccg cggtggcggt gcggagaaaa aggtcattat tacggataat accagtggag
      721 tcgctggctt tcatgatgcc ttttacccag ctgacagtgt cggcggcggc caccgcagta
      781 tctttatttt tatagagcac ctgctgtgca acaccttgcc ggcagaggcc cagggtagct
      841 ataacgacaa tggctatacg ttgtaacagg taaaagagat acttcataca tgcaatgttt
      901 aggaatgaga ttccctgcgg cataagcggg gcttataccg gcaaacggaa acaggtggta
      961 tttcttcagt catcagcggg cataggtatc cctgttcctt tgcaggaaaa aggaaaaaag
     1021 tgacccgtga tgtatgcaga tcaggactac aggccggatc aggaagatgt aaggccgccg
     1081 tacagcgggt agtaacggat acgtacaggc aggcgcacgc gcatgtcgtt caggaacggt
     1141 aaaggtgttg ccatgtgaaa gaaattaata aacgtgaaat tctagtctta cttcggtttt
     1201 ccgggtttaa tgctatactg ctttgccaac gcgggtctgt actctggggc gcttcagtgc
     1261 tatgcagtat atatcgtttt aaattttggt tgttgttttc agctacttat caaatgtaaa
     1321 cagctaaacc gatttttcat agttttcagc aagaaatttt taaaataatt ttcaggcagg
     1381 ataactaccg gtgaatcgct ttcttttcgt atatccctct cagttatttt ttacgtttca
     1441 gcatcagatt gctcctgtgc ggggaaaccg cggcctgccg gcatccggac tgaaccggta
     1501 taaccggaaa cagccattca gagctgctcc gcgcatataa ttccacatac tgttgctctt
     1561 tccggacgta cagccagcag ccacatccct gtaaacagcc cctgcatggc atttataacg
     1621 ggcattgcct ttgatggtaa tctggataag atcaaaccat tgttgacatt atatttcatt
     1681 tttatgtact ccgacgtaca aattcttatt gtagatgatg accccgaaga cgtatttatt
     1741 atgcagatga tgtgcaaaga gttatccttc ctggaaaacg tacactttgt acccgatgga
     1801 ctgacgctat tgcactacct ggatggacta tacgaaaatc agctgccgct gctgattatc
     1861 ctggatcaga acatgccgcg cttcaatggc gtacagacac tggaagccat ccgcagcaat
     1921 acccggtatc atctgttgag ggttatcatc tatactgact taccggatgc attgcagtca
     1981 aaccggctga aagaactggg agtggaagcc tttgttacca aacccaacac ctacgaacaa
     2041 ggtcttgaaa tcatgcagca gttccatgac tgcagtaaag gtggctatac ctttcccatg
     2101 gctgctaccg gctgatcagg caaccgctgc ctgctttctg aatgcagaag gattcatgcc
     2161 ccggtatttt ttaaataacc ggttgagatg actttcatct gtaaaattca gctctgccgc
     2221 tatttcatta atacgcatgt cactgtgctg caaacgggtt tccaccagct tcagcttata
     2281 attggtaata tagtcctgca tattctcccc cgtatgcttc ctgaaatacc ttcccaggta
     2341 actcaccgaa ataccgaact gcttcgctac tacctctgca cgcagctcct gcggtgaata
     2401 gatatgctcc tgtatataac ggataaggtt caacgccatt actgccgtgt tgtctttcac
     2461 ctgctccggc agcttcagcg ctatatttcg cgctactatg gtaataagtg tattcaccag
     2521 ctgggaaatt acctcgccgt gatacagctg ccggccttca tcctctttca gcaaaccgtc
     2581 taccagcgcc ggcaccagct gcttgtcggc cgccgcatac aacagacacc ccggctgatg
     2641 actggcatta cccaggataa attccatgcg ctgcctccag tcctgcgtat acatcagggc
     2701 cgtctgctgc cggttcaggt atacctggct gaaacgtaaa aagaaaaaac gggtacggac
     2761 atccagctca aaatgatgcg tatcctgcgg tgtcagcaaa aagagatgcc cggtttcaaa
     2821 acggatggag ttaccattta catactggat gccactgcct tccactatgt aaatcaactc
     2881 aaaaaaagtg tgctgatgcg gcactacagg acaggaatcg acctccttat atattatctc
     2941 aaatggctga tatatgtttt ccctggtcat atcgttgtca gaatcttact ataaaaacga
     3001 aaaattgtac aagtaaaatg cgcttaaaat tgtacaattt tacaccatca aatatacact
     3061 atccatcagt aaaaatacca taaacatgaa agtattaata gtatacgcac atccggaacc
     3121 cctttccctc aatggttcac tgaaaaattc agctgtcagg atattacagg aaaacggcca
     3181 cgaagtagta gtgtcagacc tttaccagat gcaatggaaa gccgccgccg atgaaaacga
     3241 tttcagctcc tatactcccg gcaaccgcct gttctacagc agggaagcca gggaagcact
     3301 ggctaacggc accctgtctg ccgccgtcat gactgaacag gaaaaaatcc gctgggcaga
     3361 caccatcctt ttcgtattcc cgttatggtg gttcagcatg cccgccatca tgaaaggctg
     3421 ggtagaccgc gtattctccg ctggcttcgc atacggcatc aaacaacgct acggcatagg
     3481 taacctcagc ggcaaaaagg taatgctgat ggtcaccacc ggcggcatgg aagaaaacta
     3541 cctggaaaaa ggcggcatca acggcagcat gtccgacctc ctgtttcata tccaccacgg
     3601 aatatgctgg ttcaccggcg ccgcttcact cccgcccttt gtagtatata gcgccgaccg
     3661 cctcacagaa gataaatatc ctgcggtgga aactgccctg gaagaacggc tccttactat
     3721 ggacaccacg cctgtgctgc ctttccgtta cagcaacagc ggcgactacg acgaaaaaga
     3781 tgtactcctg ccacacctgg cagcaggtaa acagggattt gcactgcacc tgagagagga
     3841 actaccgctc caggaaatga tcgatactga tacggccgcc gccatagacg agcaacgtaa
     3901 ataagaacag gatataatag agcggaatct caaagccatt atcgccggcc tcgaagccat
     3961 tggcaaggtg tactgtgata atggctacca ccatactgat catcagcgga atggtgataa
     4021 agcggacaaa aagtcccaac gttaacaaaa caacgcccag cagctccgta acagctacca
     4081 ggtaagcatt gaaataaggc agcggtatct gcagctgcgc aaaccagtcg ccgataccat
     4141 gaatatcttt ccatttcatc atcgccgggt gccagaagcc atacgccagc accagccgga
     4201 tcagcagcag cggccagtcc ctgagtactg acagccggcg ggcaaaggaa gcatataaac
     4261 gcatatgtca ggattgaaag cccagcacaa aatgttgccg ttgcatctgt tgcagaaaag
     4321 ccagtgtatc cctttccagt gtatccgtta acgttattcc cagctgtggt gcatattcca
     4381 gtatatcctt caacgttata cccaccgcca gctgctccgt aacgaaagcc agccacggtg
     4441 aaagatccgt aaactgtaca ttgcccgttt cagggtcccg gtacaataat acaaaccagg
     4501 cgccctttcc ctgtaccagc tccgttgcat ccccatgcag gtgcaccggg taacggaatg
     4561 ccagcaacct gtattccgga ttcagcacca gcggcgtttc cagccagttg ccaccctgct
     4621 gaaaaggcgc tgccggtata tcttccatat tatagacttc cgtttccgcc cattcaaacg
     4681 ccagcaggtc attcagataa ggaataccat acacctcctc ccagttctgc tccaccgcat
     4741 aggtgtaaaa ttccagcggc agcttccata cctggtacga ctgacaggca tgatgtgtaa
     4801 aaaagtcctt caccattttg ttccacttcc gcgccggaat atgatgaaag gcaaccggga
     4861 agccatcttc cataatatcg ttgataacat tgaacaccag gcggcggtaa tgtttcagcc
     4921 tgccgggcgt tacccccggc agctttacag catttccgct gcggcaatac gcggaaaaac
     4981 gctgttgaat gcggtaagta tcaggcaaca agttcatttt gcgatgtcca ttgtttttga
     5041 cagatagttt tcagcctgtt cagctcctgc tgcagttcct gcatttcagg aatgttaaaa
     5101 tccctctcca gcagcaccgg taccggcttc aggtactgga tcgtccattc aaacaggtca
     5161 tacaccgggt caataacagg ttcgccatgc gtatcaataa ttaaatcctg cgatacctgc
     5221 gtatgccccg ccatatgtat ataggcgacc ttgtccagcg gtagctgttg tataaattcc
     5281 ctggcgttgt attgatgatt gaaggcattc acatagatgt tgttcacatc caacagcagc
     5341 tggcagccgg actgccgcac cacttccccg ataaaatcgg cctcgctcat ttccgcagcc
     5401 accggcgtat aataggatac tatttccatc accaggggac gctgcaggaa atcctgtacc
     5461 tgcctgatac gcgcggcaat atgccttacc gcatccatcc ggaacggaat gggaagcagg
     5521 tcatacatat gcgcattatc gcatttggaa tagctcaggt gctctgaata aatctgcacc
     5581 cggtaatctt ccaggaattg tttaacatgc cgcagaaagt ctctgtcaag atcttcggga
     5641 ctacccacag acaacgaaag accgtggcat aataccggat acttctctac cacctggtgc
     5701 aatatcttct tccagtttcc tccgatatgc atccagttct ccggtgcaaa ttcaatgaaa
     5761 tccggcgtga tatgctttcc gctgattata tctgccgcaa aatcgcgacg aaaaccgact
     5821 ccgaccatgg tctgcagttt aggtgaaagg aaaaaggccg gaaggctgta actgtttgct
     5881 gtaccgtctt tccggccttt gaaattttac gcacctttgg tggtatcgga tttaggcttg
     5941 tgtccttttc cacccttttt ctctcccttc tttttgtcag tgccacattt gccctctccg
     6001 cattttcctt ctccgcactt accttctttc cctttcttaa caccggcaga atccttttta
     6061 gcaccgcagg ccagctccat agcactggca gcagcgccgt taccggttaa ggcacttctt
     6121 accgcttcgc cagtacccat atgatggtag ctgacagggt tggcagaagc aggttgcgat
     6181 gcagcaaaac caagaatagc agccgcaacg agggaaccgg acagcagcat ttttttgctg
     6241 atagatttgt tgttttccat tttgttacat ttaaaaagac tgagaaatga atgatataat
     6301 aaactgatac tgataagaag acgtgaataa ttacagttga tgatgcatat gccggaatag
     6361 aactgcttcc tgaaatcgcc tgacttcgcc tggccgggtc gggtgtaaaa tcctcaccgc
     6421 aattactgca ccattttacc agcttcggaa aagccccttt ttgtaatatt tgctgtaaga
     6481 atcttacgca attttagcag ttttagtttt cccctggtca caaataaatg ttatttctgt
     6541 ttttatccta tttttggact gcacgcaaat gtgtgataag aaataaaatc tgcccatgaa
     6601 agataagatg ccccctgtaa catccgtcta tttcactaca ttgatgaagg catatttgcg
     6661 cggaactaaa acaagagagg aagtactgca ggacctgtat gatgcggcac acctgcaacc
     6721 tgcagatacg gaggacaatg aggaagatat tacccggctt atactgagaa cagcttctgc
     6781 tgtcaatgag gactattacc aggaagtgat cgggtctata acccaggctc ctgatgccat
     6841 cccttcccgc gccggtgtga ttcaccagct ggaagcgctg ctgcatgggc gcattacccc
     6901 ggagcagttg ctgcagtggg ctacctggca caacgatccc ggagaggatg acggcgtcag
     6961 ctattttgac gatattgctg tagactattt ctgtacgcag ctgttgccga atccgccgga
     7021 accgtttacc cctgcccact tcgagcaggc gttaaaaatc tttaccggca accgcaacaa
     7081 tccgctcaaa gataaagtgg cgctggtatt gcttttcgac aaggaacggc agcgttttct
     7141 cttttacgtg ggcgattata tccaggggca taccgctccg gaacaactgg atgtttacct
     7201 gatgaacaaa ttcggtatgg atcattactc cttcccgtat atgggtacgc tgtccaacat
     7261 catgcacgac ccggcaaaac tcccggcgct gctgcatatg gcagcctaca cagaataatt
     7321 attctatcac tgccgccacc ctgacccggc ggttttcatt tttcacaata tcggtggtat
     7381 aggtatctac ccggtcgcca ttgctgtatt caaggtgcat ttccagcggc atggctaccg
     7441 gagggtaact accggcaacg agcatacgct ccatctcgtc cttgtactcc tcagggatca
     7501 aggcatatcc cggaaacagc gtatggggct gcattggcgt ccagacggaa gctgttgcca
     7561 gcgcatgact ggtaccccca atggtactgt cgcggcggat attatctgct ttatattctt
     7621 cacaggccac gcctgcaatt acttttttct ctcctgtttt tatcagccgg ttgagatatc
     7681 ctgtttcgcc ggggtagaca ggttccatgc tatgcaggtc cagcttttct ctggtaccgc
     7741 tgccaatgtt atgaatcgct gtaatgctca gctgcgcgcc ctgccggaag tccgcataaa
     7801 actggtaccg ggcgcccgta cttttgctga ccaggtgtac ggccagctgc ggcctggcgc
     7861 tgctgtagaa tacgatgatc tcctccccgc cttttactac ccgctgatta ccttgccagg
     7921 cttcggtttc ctggtatact gcgatgtcga attcaaaaac ggaatccagc tgcagctgcc
     7981 cgctgccgct gatagtcagg gaaggctgcc cgttcaccgg gccattggca ggcgtttcaa
     8041 aaggaccttc tgtcagggag gaatcggtac gcacggcagt caggctgcgt acccggtctt
     8101 tcatctttct caggaattgc gcctgtacag cagaaataca acatatacaa gccaggaaca
     8161 gtaatgcctg ctttttcata ggaatggtat atattatgta aatctactat aaataaatta
     8221 actcaccatc aggctgcagc cccggagtgc ggaattatcc agccggccca gtacttcaaa
     8281 acggccgtcg gcatgtattt tacctatatc ttctgtggca atgaaagcgc aggaataaat
     8341 attggcgagg tctatcacat tcattacacc agcgcctttt ccggctgtca gctgaaaggg
     8401 atcattttca tcgcgcagca ggattttcat ccaggcgggt gtctcaaaaa agccatggcc
     8461 tttggaatag gcctgggaca ggagttctgt cataccgtat tcggcatgta cttcctttac
     8521 gcccagccgc tctttcagaa aagcgtgtac ctcttcccgt gtccactctt cccttcttcc
     8581 tttcatacca cctgtttcca taacaatggt atgttgcagc tgcatggtat atttttcggc
     8641 aaaatccagc agtccgaagg taacgccgat cagcagcact ttctgctgcc gcgcttccag
     8701 cgcctgtagc tgatggaata acttatcgtg ttcgtacagg taaaaaccgc tttcttcccg
     8761 gccgctgcgc actgccattt cctgcaccat ccgcaccagg gaagaatgct gccgttccag
     8821 gtacgaaggc aggaggccta ccactacata gtctgttact ggaccgtaaa actgctcaaa
     8881 ggccgtcata aaactttgtg tatatacggc ggcatctttc accaggtgtt tactgttgac
     8941 cgtctgcgta gtgccgctgc tctcaaagat cagctccggt tcaaagtcac cgcaggcgac
     9001 ccggtgtgtc ttgaaaaact ggatgggcag gtagggaatc tccaggatac tctttacccc
     9061 tgcaggatta atatgcaggg catcggtata agcccggtaa atgtcattct cccggtactg
     9121 ataccggaaa agctccaggg cggcagcttc cagtccgtct ggctgtaatg aaaatatatg
     9181 ttccggagaa acgacctgca tattcatcta tctttaaaat cgtacaaagt taggcagaag
     9241 aataaattta cccgcaggaa gtaacaatta gcttaaaaaa aacgttttgt cctgagtacg
     9301 cagagatagt cgataatttg tatatttcct aaattaatgt aggtttgttt tatgaagaaa
     9361 actctctttt tattcctggc ggctggtctg atctatgcct gtaaaaaaga taatatcggc
     9421 tccaaaccta tggtatcttt caaaagctat tccgccgaca gcatcactcc ggaaacccag
     9481 cagttcaatg taacgctgcg ggtggaagat ggcgacggcg atatagagga cagcatctgg
     9541 ctcgccatcc tgataaaaag ccagcaggaa gtaagcaagg atacattatg gggaaaatat
     9601 aaaatgcccg gcatcgggca aaaccggggt aaccgtatta aagcagatgt tatcctgggc
     9661 ctgcagcagg aacattttgc ctttaactat accgcacgcc ccaatgacag cgcacatttt
     9721 gtgacctacc tccgggacag ccgcggaaat atcagcgata ccattgccac gccaatattt
     9781 cccttccgca gaaatcaata agtgtaaaaa cattacattt acaacataac aaggattcct
     9841 tcgtaaagga atccttttat ttttcagatt taaccttcat tttcagcata tgaacaaaat
     9901 agaagaatta cagtccagga tcaaggaagc catgttaggc ggtggtgaag tccgtattgc
     9961 ctcccagcac aaaaaaggaa aactgacagc ccgcgaaaga ctgcagctgc tccttgatga
    10021 aggctccttc gaagagctgg atatgctggt cgcaaaccgc aaccgcggca tcaccaccga
    10081 acaggaacag tttcccggcg atggcgtggt taccggctac ggcaccatca acggcagaat
    10141 cgtgtacgtt ttctcacagg acttcaccgt gtatggcggt agtctttctg aaccgcatgc
    10201 ccgcaaaatc tgcaaggtaa tggacctcgc catgcagaac ggcgctcccg tgatcgggct
    10261 gaacgacagc ggcggcgcac gtatacagga aggcgtggta agccttggag gctatgcgga
    10321 tatcttctac cgtaataccc gcgcctccgg cgtgattcca cagatctccg ccatcatggg
    10381 accctgcgcc ggcggcgccg tatactctcc cgccatcacc gattttatca tgatggtgga
    10441 acaaacatcc tacatgttcg ttaccggccc taacgtggtg aaaacagtga cccacgaaga
    10501 agtaacttcc gaagaactgg gcggcgcgca tacccacgcc accaaaagcg gtgtcaccca
    10561 ctttgcctgc gccaacgaag tagaatgtat tcagaacatc aaacaactgc tcagctatat
    10621 cccgcagaac tgcgaagaaa ctgcccccgt atatccgtac gagcccggca atgaaagcag
    10681 ggaagccctc aacacgctca tccccctcaa tgccaatcag ccttacgata tgaaagaggt
    10741 catcagccac ctcaccgatg cagacagctt ctttgaagta cacaaggatt tcgcggataa
    10801 tattatcgtt ggatttgcac gcatcggc
//
