LOCUS       NZ_JAABOK010000009     25379 bp    DNA     linear   CON 29-MAR-2024
DEFINITION  Chitinophaga solisilvae strain O9 NODE_9, whole genome shotgun
            sequence.
ACCESSION   NZ_JAABOK010000009
VERSION     NZ_JAABOK010000009.1
KEYWORDS    WGS; RefSeq.
SOURCE      Chitinophaga solisilvae
  ORGANISM  Chitinophaga solisilvae
            Bacteria; Bacteroidota; Chitinophagia; Chitinophagales;
            Chitinophagaceae; Chitinophaga.
REFERENCE   1  (bases 1 to 329547)
  AUTHORS   Jianli,Z. and Weiwei,P.
  TITLE     Chitinophaga flavus sp. nov., isolated from forest soil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 329547)
  AUTHORS   Jianli,Z. and Weiwei,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-JAN-2020) School of Life Science, Beijing Institute of
            Technology, 5 South Zhongguancun Street, Beijing 100081, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.5.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 246.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009928525.1-RS_2024_03_29
            Annotation Date                   :: 03/29/2024 05:41:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,090
            CDSs (total)                      :: 6,009
            Genes (coding)                    :: 6,004
            CDSs (with protein)               :: 6,004
            Genes (RNA)                       :: 81
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 16S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 0 of 5
            Pseudo Genes (incomplete)         :: 5 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:41:33
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 13149
            Orig. end                         :: 38528
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAABOK010000009.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25379
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..25379
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25379
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15379](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15379
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    complement(473..491)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 22.4"
                     /tool="antismash"
     gene            complement(478..1578)
                     /locus_tag="GWG06_RS19115"
     CDS             complement(478..1578)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018305.4"
                     /locus_tag="GWG06_RS19115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="histidine kinase"
                     /protein_id="WP_160715213.1"
                     /transl_table=11
                     /translation="MGKSTTQEKLFNRYYRIFIFPMIFLLYYLLSYLVNPFSGYWEELW
                     KQKWTDILIEGVIMMIFCALITEMSLIIARQLNKIMPWNEKPIARSFIQLLLQLVSVGL
                     LLAFLYYTLFFIFGPPPKATKPPDKLDEWQFVFVCSMLAILISAVHTGHYFLQRWKTSM
                     LEASELKLKAAEFKQIAMQAQLQSLKLQLDPHFMFNNFSALSALIMEDKDVALSFLENL
                     AKVYRYMITNLNNDIITLAEEEKIIRAFAYLIKIRHGDNVVIDIDIPASIAGRGIPPIT
                     LQLLIENAIKHNMATAARPLLIKIYEDDSGRLIVSNRIQRIRHQIQSTKLGLENIRNRY
                     RILSDQQPVIKEEDGMFIVVLPVLDI"
     misc_feature    complement(1576..1590)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 20.38"
                     /tool="antismash"
     gene            complement(1645..3060)
                     /locus_tag="GWG06_RS19120"
     CDS             complement(1645..3060)
                     /GO_component="GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /GO_function="GO:0015288 - porin activity [Evidence IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1076: RND efflux
                     system, outer membrane lipoprotein,"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012791213.1"
                     /locus_tag="GWG06_RS19120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="efflux transporter outer membrane subunit"
                     /protein_id="WP_160715215.1"
                     /transl_table=11
                     /translation="MKEKISLILVMAVICVTTACRVGKDFTRPAVALPDKYRGAGAATD
                     TTSIAGIPWKSFFTDPVLQTLIDSAIAKNFDMLTALKNVEAAERSVRASRLGNLPDINL
                     TVQGNRNWPSKNSLNGSLSQEFIGTRFMDDYNANVGLSWEVIAWGKISRLKEAALADYL
                     RSAEASKAVQTKLVSDVAQGYYNLLMLDNQLEITKKNLALNDSTLRIMRLQYESGQTNT
                     LAIEQTEAQRDAAAALLPKIEQQISQQENALRLLTGDLPGSIARQANLQSVRFDGQLSA
                     GVPAALLSARPDVHAAEMSVMAANARTGVARANMYPALNITASAGLNAFKASSWFSIPG
                     SLFETVGGSITQPVFQRRKLKTEWETAKIEWEKSVISFRQSVLTAVGEVSDALVKIDKL
                     KAQYSITQQRVQKLESATRNASMLYQNGMANYLEVITAQGNVLQSELDLAAIQREQLGA
                     VTELYRALGGGWK"
     gene            complement(3086..6265)
                     /locus_tag="GWG06_RS19125"
     CDS             complement(3086..6265)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) RND_efflux"
                     /gene_functions="transport (smcogs) SMCOG1049:
                     AcrB/AcrD/AcrF family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018629690.1"
                     /locus_tag="GWG06_RS19125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="efflux RND transporter permease subunit"
                     /protein_id="WP_160715217.1"
                     /transl_table=11
                     /translation="MLKKIIQRPVLATVISVILVILGVVGLTRLPVTQFPDIAPPSVMV
                     SASFPGGNAATVLRSVVTPLEEAINGVENMTYVQSTASNDGSASISVFFKLGTDPDQAA
                     VNVQNRVAQVTSTLPPEVVQAGITTTKQQNGMIMILDIVSGDQKKYDEAFLQNFAKINV
                     IPELKRISGVGQVQVFGGKDYSMRVWLKPAALAAYKVTPAEVMNAIRDQSLEAAPGKFG
                     EGTDAALSYVINYSGKFNTPEQFENIVVRVAPDGSVLFLKDLARIELGSATYATDNRVN
                     GQDAVTMAVFQTNGSNANAIQTTVKEVMENAQKTFPKGIRYQITMSTKEQLDTSIAQVK
                     STLIEAFILVFVIVFLFLQDFRSTLIPAIAVPVSLIGTFFFLQLMGFSVNMLTLFALVL
                     AIGIVVDDAIVVVEAVHSKMERSHLPAKAATLSAMSEITGAIISITLVMAAVFLPVGFM
                     EGPTGVFYRQFAFTLAIAILISALNALTLSPALCALFLKNPHTAEGDNENSNGHTKKGF
                     GRRFFTAFNTGFQAMTYRYTRIIKWLISYKWVSLGSLAVIIAAVVYLMRVTPKGFIPNE
                     DGNFVAWSLSLPPGAGLERTTKALEKADSVLKTMPMVVSGTSISGYNILSNAASPAYAM
                     GFVKLKDIKDRGEVQQIDHVVAVMTERLSTIKEGTFSVFTFPTVPGFGSFNGLELMLQD
                     RTGGSVQNFSETANNFIGELMQCPEIGVAFTMFKADFPQFEVQVDAVKAKQLGVSVSDL
                     MMTLQTYYGSNQASDFNRFGKYYRVMVQAAPEDRSDAASMEGVFVKNEQGEMVPVNSIV
                     TLKKVYGPEMMNRYNLFNAIAVNAMPKPGYSTGQAMQAVERVAATKLPAGFSFEWTGLS
                     KEEKNSGNQMVLIFALAIVFVYFLLAAQYESYILPLAVLLSIPTGLIGVFLAINMVGID
                     NNIYVQVGLVMLIGLLAKNAILIVEFAVQRRRAGRTLLSAALEAARLRLRPIIMTSLAF
                     VVGLIPLMSVKGPSAMGNVSISIGTAGGMLTGVILGVFIIPVLFIVFQFLQEKVTGKKP
                     AEHAVAEEVHA"
     gene            complement(6287..7474)
                     /locus_tag="GWG06_RS19130"
     CDS             complement(6287..7474)
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1029: RND family
                     efflux transporter MFP subunit"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012790438.1"
                     /locus_tag="GWG06_RS19130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="WP_235938425.1"
                     /transl_table=11
                     /translation="MKQLLHTGGRRGTICGLALLGMLAAGITGCGGNAGAAAGAEAMPP
                     QELPVATLDTTTAMTTKAYAAQLEGKVNVDVRPQVDGYLDKIYVEEGSYVKAGQPLFGI
                     NDQPYREQLNKDIASLHAMESALAAAELEAEKIRPLVENKVVAGIQLKTAQATVQTAKA
                     NVEQAKAAVAASRINMGFTVVKAPVSGYIGRIPKRIGNLVGKTDASPLTTLSDISEVYA
                     YFSMSENDFMDFSHGGAAGNLSQQIKQLRPVTLVLSNGTDYTHTGRIEMVDGQFNKATA
                     AISLRATFPNPSSVLRSGNTGKVKIETLNSGVLLVPQAATLEMQNKVFVYQLGDSNKVK
                     RQIIDIAGSSDNNFLVKGGLKRGDKIVTAGIETLMEGAVVTPAAAPKDSAAAKAK"
     misc_feature    7451..7469
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 24.1"
                     /tool="antismash"
     misc_feature    complement(7754..7767)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.06"
                     /tool="antismash"
     misc_feature    complement(7756..7772)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 23.49"
                     /tool="antismash"
     gene            7775..9979
                     /locus_tag="GWG06_RS19135"
     CDS             7775..9979
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="GWG06_RS19135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_160715219.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.2e-32, bitscore:
                     106.6, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQKLFTRKKFPFYKQSDGMDCGPTCLKMIAEHYGRKFPLQYLRN
                     ISKLTRQGVTMADLEATAEQLGFNTLPASLHIQVLTDKAPLPCILHWEKQHFVVLYDIT
                     KTHAFIADPALGKPVSYPLADFLAAWEQEPGSRTGRALLLEKTGRFNEGEAVPDKDVRL
                     WSLLPWLRPHTRRLPAVAGTLLLASACSLLTPLLTQRIVDTAITGKNLPLLLLICTGLL
                     LLFTGRTLMDFIRARVLYKAGALISIQLLKAYLEKLMRLPLAFFDNRHAGDNMQRVTDN
                     QRVEDFLTSSLVNFMLSVITIAVLGGALLWYNTWIFLLFLTSAAVSVLWANSFQEKRRI
                     LDQKKFRILSANQHILLEIFSAMQEIKLTGSEHLKSTQWEALQDKSLALKLDSLRMDQF
                     MQGTGAFINEIKNILITGVAAMLVIEGQITLGAMLAITFICGQLNAPVLQLAEFIRVSQ
                     NTRFSLQRMEEVQQEPDEDPPQAAPFPDITEKDIRLRNLCFQYGHKHSPMVLQHVSLVI
                     PAGKVTAIVGMSGSGKTTLLKLLLRCYAPVSGQILVGTVPLQSLPAREWRRHCGVVMQD
                     GYIFMDTIANNIYAGAQIRDESRMFRAAEMACIHDFFSSMPFGYETMVGKDGYGLSEGQ
                     TQRLLIARLIYRNPSFIFLDEATNSLDAHNERAIIGNLHQFFPGKTVVVVAHRLSTVKH
                     ADQIVVMDKGQIVERGTHAALAASNGAYYQLIKNQLELGK"
     misc_feature    complement(7780..7789)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 17.48"
                     /tool="antismash"
     gene            10001..12619
                     /locus_tag="GWG06_RS19140"
     CDS             10001..12619
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="GWG06_RS19140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_160715221.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 2.8e-20, bitscore:
                     65.9, seeds: 73, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVNIFPYTLTRYSTIHHRDFRPLTLPGIRRQLWLQQRTGELVIA
                     GREALCEGLFHLIREQEDDSLRKQLIKLKRELQQDKLPAQLPPGLPAALQVQLESQLRL
                     LLRRQSLPASWQAYYDRRLQQYRQQLQQWTRNPLLLNGLLLSSPVLYEQLPAYTTAHPA
                     AFRHKELKIEYSLLRYITRMAFKTSPFSTFTYTGLTAVTAEAATTAPPAMSHSSIRLNN
                     TLFTTLQSLMLQHPLLNEALYLRLNSSIARENGQLLFLVNCFNIESFQRMPDSGIMQWL
                     YAFITNSRERVSLQTVTDALHAKLADTDRDTVKAYLLKLVSSGLLEAVTGCSAVHPQWE
                     EQLLQFCRDNLAVHTALLPVHELLQQLFTSRRDYVYASPADRYRLLQDAATLINQSLET
                     LYAVPELAAALAAPESAAAKIRESGAFVTDMFARRNFSPAGIFYEDAAATGIGHLPAAD
                     IHAFTATLEKLFQSLTPLDDLQEERTSMRDFFLKHYEPDEQIAVTTFYHQYYLEEKKVR
                     KTQQGDRSLLPVSEATKQRLESLLDTHFSNAFHAEISAREVALPDRRHAGAAFVQFYRG
                     PAGLTGVVNNLLPGMGKVAGRFLDLFDPSLAAQFCDWNQALYPDHMLMELSDGSSFNAN
                     IHLPLLPFEIAVPGGYNNYPAEQRARLQDVLVRYDEASQQLWLQHAPDQRRIFAYDLCL
                     ESFYLRSNFYQLLAHFNPEPYLPLKKFFRLTDDAHATAFPEQGHIRPRITFESKVVLRR
                     MGWLVQTADIPQQQTAETEAAWFLRVQQWREQQGIPEQVFLFLRSRYSKADKDSPSALQ
                     RDDYKPQYLHFGQPLLMGLLKKLLARAGTQIYLEEMLPHTSDLQQEPVTEQLLHWYNYG
                     T"
     gene            12616..13548
                     /locus_tag="GWG06_RS19145"
     CDS             12616..13548
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03891.1"
                     /locus_tag="GWG06_RS19145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_160715223.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.4e-38, bitscore:
                     127.1, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHPSNSWSAANRSALPNTGTAWLSAHIYSRGPLDRLINLLAAPF
                     TATVAACLHPVSPFFFIRYGEGGPHIRLRLHVNTSHTETVRHMLKEAAGNYFSEYPSVP
                     VSGGEMPLHDTLAFMHYQQETARYGNQHTIPLAEEQFYLSSRLVMEQLQNGAAAASLTY
                     GIQLHLCFFMAMQTTLADIQRICTRFIQAWSPSLAGSMNTPEQAALINTHMENMYRQYA
                     PSLLPASETLWQQLKQGKAPPALQSFTYRNSRLLQRYYHAGLAAGQLEEAFCSMMHMSH
                     NRLGISNAEESWCVFLTLKCISHLYEYDR"
     gene            13532..15379
                     /locus_tag="GWG06_RS19150"
     CDS             13532..15379
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="GWG06_RS19150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="WP_160715225.1"
                     /sec_met_domain="LANC_like (E-value: 2.7e-52, bitscore:
                     171.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSMTADHQRINDAVMSTAARLLQAAQEDEHGIYWITPPHIQGGAP
                     GESTDLFNGTTGILFFFLSLYDYTGEAAYLRVCIRGTARLLQHPEIRQPAFYPFYTGAT
                     GILLLCIRMHRYTGNSDYLEQALLLTYSYQQGILQEVKKDDLLSGDAGNLLLFTHLYAY
                     TQHPCYLEIMRQLIDQLLSHARIAPAGLKWDPVKQAYDSLTGFSHGGSGIAFALLQAAR
                     CLHSDGLLYLAEQALAYENTYADPARNNWMDLRTGVKRMQQLADTQGAAILKWELTPFL
                     AGMSHLNTWAHGAAGIGIARLHIWEHTHHPAYMADIQQALRRCLADAAADNRGDYTLCS
                     GYGGIAAFLVEAARILKQPYLTAAAQRIAIAAIDYSEKHHTYNSHLITDPEDPGLLSGL
                     AGAGYFLLSTIHAPGPDSILHPAINTENTEINVNAYTLNEIKEKLFSRYYPRTWQTLTQ
                     DETIAGILLQARDIPGLRILLREQIIRHPDARSLFLNEDTATDLWLQHKGWLQHRECRR
                     LQQQLIQQVTEHRLLVISRHVKVCGQVIWYSHDTGINSTSAGKLTAVILEWLATPMSMI
                     QLQEQLMQTQPPGTPDAVAYNIITAQVNELLQCGFITPA"
     gene            complement(15381..15701)
                     /locus_tag="GWG06_RS19155"
     CDS             complement(15381..15701)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GWG06_RS19155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_160715227.1"
                     /transl_table=11
                     /translation="MKQEALKKDILSVLEGDNAEDDRWLRFSRKIDEGIGAGWGRREVF
                     AVLRDIFEHHAAGLSEQVQEELKEFENTITGFCDPVDIYRFPGDPQEVEALSAKVRSNN
                     WR"
     misc_feature    15722..15731
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     misc_feature    complement(15829..15838)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     misc_feature    complement(15837..15846)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     gene            complement(15907..16092)
                     /locus_tag="GWG06_RS19160"
     CDS             complement(15907..16092)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038180.1"
                     /locus_tag="GWG06_RS19160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pinensin family lanthipeptide"
                     /protein_id="WP_160715229.1"
                     /transl_table=11
                     /translation="MKENNVSNLKLSLEDLKIESFVTSIDSEMSMRLAGGLAAQAHPTH
                     TERTDDEGHFCTTQIC"
     misc_feature    complement(16084..16097)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 19.99"
                     /tool="antismash"
     misc_feature    16211..16226
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: strong, score: 26.8"
                     /tool="antismash"
     gene            complement(16223..18319)
                     /locus_tag="GWG06_RS19165"
     CDS             complement(16223..18319)
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_function="GO:0015343 - siderophore-iron transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1051:
                     TonB-dependent siderophore receptor"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:TIGR01783.1"
                     /locus_tag="GWG06_RS19165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TonB-dependent siderophore receptor"
                     /protein_id="WP_160715231.1"
                     /transl_table=11
                     /translation="MKKEVRFLLLFLIMASSVCAQQQPDSIRRMRLREVEVQEKKKRLR
                     ADSIPAGLRLEGSLIETPQNIVSVSSALVAEQGGLVMKDIVRNASGVHMGYNTNLFDGS
                     ATIFIRGFPAPTYVNGLLQRTTIDDAAIIEQVEFIKGPAGFLASAGEPGGTVNITTKVP
                     LQRRVRSVEIAGGSFGMWRASVDLGSMIKTKGFSWRMNAAYQQERSFLDFLQTKKYVLA
                     PVVQYNFSPRTSVLLEYNLLRASSAGGSGLNKVGTDEEIRHARIADNFAGDPGLPGSYG
                     ETQSVRFLFNHALSKSWKLVAQGRYTSTPAETWYLFSANQSPVNFINDTTRRLPVRNHS
                     TGQVVASQLYVKGVFNTGTAIRHYLMTGVDFNYARDVYNYTTGQYSFYFDRRQPVYGLH
                     TDSVRMLKAAADQVDENNWASAYAYDMIHVGEAWRINIGGRYTRNTRPGKELQQAFSPR
                     LGITWLLRSNLSVYALYDQSFIPQTGSDFDKNLFKPLLGNDFELGVKGDWFNKRLSTTV
                     TGYRIIKNNMLVADPEHRRFRKQIGQVKSTGVEVDVMGQITDRFTVSANYSYTDAVISK
                     DTKPANVGTALPFMPQQNINTWLQYSIPVSTARLRLSLGQRTAIRPGTYTPDLYLPDYT
                     LFDAGASWDAGKWYVRIVAENITNRRYFSSGDILIGSVYPDVKTTYYIDGTPINFKAFA
                     GIRW"
     gene            complement(18340..19770)
                     /locus_tag="GWG06_RS19170"
     CDS             complement(18340..19770)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024091.4"
                     /locus_tag="GWG06_RS19170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF3526 domain-containing protein"
                     /protein_id="WP_160715233.1"
                     /transl_table=11
                     /translation="MRYSIQIIASELRALFRTAVLPVLTAVCLAAGSCALFYGHHVTQQ
                     RVAGIDSMQRQYTERYTAMYTSLRADTATEQGKQNYQAAIEPAVVEYRLYNNAVQLPGA
                     MSVLAIGMSDVARHYYPVKINAGYTPAEEKLSNPQQLMTGNFDLAFVCIYLLPLMLIAL
                     TYNLFSQEQEQGTLKLLIIQQGSFRRILLMRLCIRWVLLLLLVTFLILAGIIFLPAGIP
                     VNAGEVWAWIAVTAAYTLFWAGVCWVVTTWGKSSGVNLIALLSCWLLLLVVMPAVIHFR
                     ISDTGVTDDTATNASRQRDIAWDTWELPQRQLLDSFYQVYPQYRNHLAYDTSEGSMRRS
                     MAYYQLAEQRMDRILAPQQQRRQQQLAGVTAAYAWSPAVYAQALYSRIAHTDITDDYYF
                     RQQVTAFREQWKHYFYGFYFNNRQFTAAAYATIPKYQPAGDPDAGRMIGKGILYLTAAG
                     IVLLAAGCVIAGRRNIQL"
     misc_feature    19750..19768
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 22.47"
                     /tool="antismash"
     gene            complement(19798..21219)
                     /locus_tag="GWG06_RS19175"
     CDS             complement(19798..21219)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024091.4"
                     /locus_tag="GWG06_RS19175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF3526 domain-containing protein"
                     /protein_id="WP_160715235.1"
                     /transl_table=11
                     /translation="MYKIIVAKDWQTMCRNRTWLAGCLLLLLMCGIAFTGTLQQDAQLQ
                     TQRLAADSLFRAQWDQLRAGNPHDAAHFGTWLYKPLSVLSSFDNGIHHVSGYTMRVEAH
                     VQHMPAAAPVQPADNYLRFGAFTPAAVLQLFFPLVIIFCCYQLYVQEREAGTLKLLLIQ
                     GGARGVLVRAKAGLALLLSNGLLLACLLLLLPALFFWRGGITSAISVQALLLTIAYMLY
                     ASVIALLCMAASVLLKRSNQALLLLLAGWLFAVVILPRMTAAAGDMLYPLPAQSVVQEN
                     ISRAEKSGIHGDEPRVQRQQQLEARWLKQYQVKTTAELPVNFDAILMQAAEDYMQRIYE
                     DQTRHIDSIIRLQHSITAYAVLLDPYLAIRELSMALCGADYMHHAHFFAAARRYRNDFI
                     AALNHEMAYGGSKTGDYSWKADATFFKQMPVFRYTPPGTGEILRQQYLAGISLLIWVTA
                     GLLLLGKLSRQESAG"
     gene            complement(21223..21930)
                     /locus_tag="GWG06_RS19180"
     CDS             complement(21223..21930)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012792920.1"
                     /locus_tag="GWG06_RS19180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_127044324.1"
                     /transl_table=11
                     /translation="MLQAIALTRQFGQHKALCALDLHVGPGEIFCLLGPNGAGKTTTIN
                     CFLGFVQPDSGQALVNGINVQQHREQARKHIAYIPETVMLYPYLSGLENLVFFHALTGM
                     HHSRQELLEYLLRAGLQEDAVHRRVGGYSKGMRQKVGIAIATAKQAAVLLLDEPTSGLD
                     PAASNEFSVLLQRFSNEGRAVLMATHDLYRAREVASRIGIMKHGRLLTVMDAADVDHYA
                     LESIYMEHMTAAR"
     gene            complement(21983..22327)
                     /locus_tag="GWG06_RS19185"
     CDS             complement(21983..22327)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GWG06_RS19185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_160715237.1"
                     /transl_table=11
                     /translation="MKQPGHNVWPRLCAFFLLAVLVFIQAVKTTHRHDYAGKEGMRIFQ
                     QHNPSGCTISVAAHYCAICDYQLAKEVWQPSVKPSLLLQPSWMVAYASLHITPPQAIIL
                     HCANKGPPVV"
     misc_feature    22377..22386
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     misc_feature    complement(22496..22505)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     gene            complement(22507..23268)
                     /locus_tag="GWG06_RS19190"
     CDS             complement(22507..23268)
                     /NRPS_PKS="Domain: PKS_KR (6-174). E-value: 2.5e-09. Score:
                     29.2. Matches aSDomain:
                     nrpspksdomains_GWG06_RS19190_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012791944.1"
                     /locus_tag="GWG06_RS19190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_127036688.1"
                     /sec_met_domain="adh_short_C2 (E-value: 1.1e-31, bitscore:
                     104.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTGKIALVTGGSRGLGKNMALSLAAKGIDVVITYNSRKEDADAV
                     VAAIEQSGRKAAALQLNTGDIKTFDAFFQQLGQLLTSHFKADHFDFLVNNAGVGVHAPF
                     ASTTEDDFDMLVNIHLKGVFFLTQKALPWLNNGGRIVNLSTGLARFALPGYSAYAAMKG
                     GVEVLSRYMAKELGERGIAVNVVAPGAIATDFGGGLVRDNEHVNQLIASTISLGRVGLP
                     DDIGGVVAFLCTEDARWINAQRIEVSGGQNL"
     aSDomain        complement(22747..23250)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GWG06_RS19190_PKS_KR.1"
                     /evalue="2.50E-09"
                     /label="GWG06_RS19190_PKS_KR.1"
                     /locus_tag="GWG06_RS19190"
                     /protein_end="174"
                     /protein_start="6"
                     /score="29.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="ALVTGGSRGLGKNMALSLAAKGIDVVITYNSRKEDADAVVAAIEQ
                     SGRKAAALQLNTGDIKTFDAFFQQLGQLLTSHFKADHFDFLVNNAGVGVHAPFASTTED
                     DFDMLVNIHLKGVFFLTQKALPWLNNGGRIVNLSTGLARFALPGYSAYAAMKGGVEVLS
                     RYMAK"
     CDS_motif       complement(23185..23247)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GWG06_RS19190_0001"
                     /evalue="9.10E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="GWG06_RS19190"
                     /protein_end="28"
                     /protein_start="7"
                     /score="11.9"
                     /tool="antismash"
                     /translation="LVTGGSRGLGKNMALSLAAKG"
     misc_feature    complement(23375..23387)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 22.66"
                     /tool="antismash"
     gene            complement(23393..24298)
                     /locus_tag="GWG06_RS19195"
     CDS             complement(23393..24298)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012793947.1"
                     /locus_tag="GWG06_RS19195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_127036690.1"
                     /transl_table=11
                     /translation="MEPISLEGFYQETASLIPEGINKEIGHFNVFRIDDLFPANKPRVP
                     MSYNRRAYYKISLISGRNKAEYADKVIDIEKNALLFATPKIPYHWLPEDDHQSGYFCIF
                     TADFLVQQKSGVILDDLPIFQPRGYPVFQLTDEEAEDILFIFRKMYKELSSDYAYKYDL
                     LRNYVMEVIHYGQKLQPATALYPTHTAAARISSLFIELLERQFPVESPQQRLLLRTAKD
                     YADRLAVHVNHLNRVLKENTGKTTTDLISGRILQEAKVLLKQTDWNISEIAYSLGFEEV
                     AHFSNFFRKQTTLSPVAFRS"
     misc_feature    complement(24763..24780)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: medium, score: 26.51"
                     /tool="antismash"
     misc_feature    25035..25044
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
ORIGIN
        1 acggtgcggt aaccatcctt atagggtatc aggaagcggg agcggtaaat ggtttctttc
       61 ttttcaagat agcgcaggat gtccttcacc ggctctgata ctaccttctg ctggcgcagg
      121 ctctcaaatt tgcgcagggc ggcgctcagg tcttcctgca caatgggttt catgagataa
      181 tcgatgctgt ttaccttgaa agcgcggata gcgtattcgt cgtaggcagt ggtaaagatc
      241 acgggacacc cgatttccac ctgttcaaat atttcgaagc tgaggccatc agcaagacgt
      301 atatccatca gaacgaggtc cggcagcggg tgggacctga tccagtcaac ggtttcagta
      361 atactttcac aaacaccggg gatccggata tccgggttga tctcctgcaa catacgttgc
      421 aggcgggtgg cgttcaatgc ttcatcttct actattaaaa tctccatata caaaatttta
      481 tatatccagt accggcaaca caactatgaa cataccatct tcttctttga taactggttg
      541 ctgatctgat aaaatgcgat agcggttacg tatattctcc aatcccagct tggtggattg
      601 tatctggtgc ctgatccgtt gaatacggtt gctgacaatc agccggccgg aatcatcttc
      661 atagatcttt atcagcagcg gcctggcagc tgtagccata ttatgcttga tggcattttc
      721 tatgagcagc tgcagcgtaa tcggcggaat tcctctgccg gcaatggatg cagggatatc
      781 aatatcaata actacgttat cgccatgcct gatctttatc aggtaagcga aggcgcggat
      841 gatcttttct tcttctgcca gcgtgataat atcgttattc agattggtaa tcatataacg
      901 gtatactttg gccagattct ccaggaaaga caatgccacg tctttatctt ccatgatgag
      961 cgcagacagc gcgctgaagt tattgaacat aaaatgcggg tcgagctgca gctttaacga
     1021 ttgcagctgc gcctgcatgg cgatctgttt gaactcggcc gctttcagct tcagctcaga
     1081 agcctccagc atagaggttt tccagcgttg caggaaataa tgcccggtat gtacggcgct
     1141 gatcagaatg gctaacatgg agcagacaaa tacaaactgc cactcatcga gcttatcagg
     1201 gggtttggtt gctttggggg gaggtccgaa aataaagaac agcgtatagt atagaaaagc
     1261 cagcagcagc cctacagata ccagctgcaa taacagctgg ataaaagaac gggctatcgg
     1321 cttttcattc cacggcatga tcttgttaag ctgccgggca atgatgagac tcatttcagt
     1381 gatcagcgca cagaagatca tcatgatgac accttctatc aggatgtctg tccatttctg
     1441 cttccagagt tcctcccagt agccgctgaa aggatttacg agataagata acaggtagta
     1501 caggaggaat atcatcggga agatgaatat cctgtaatac ctgttaaata atttttcctg
     1561 tgtggtagat ttgcccatta tcggaatatt agccggggta ttgacagtta taaatgacag
     1621 ttaaaattaa caaatccacg gctactattt ccaaccgccg ccgagagcac ggtataattc
     1681 cgtgacggcg cccagctgtt cccgctgtat ggcagcgaga tccagttcgc tctgcagtac
     1741 gttgccctgt gcggtaatca cttccagata attggccatt ccgttctgat aaagcatgct
     1801 ggcattcctg gtagcacttt ccagcttctg tacccgctgt tgcgtgatgc tgtactgtgc
     1861 tttcagcttg tcgattttca ccagcgcatc agacacttct cctacggctg tgagtactga
     1921 ttgtctgaag ctgatgactg acttttccca ttcgatcttt gctgtttccc attctgtttt
     1981 gagcttcctc cgctgaaata caggctgcgt gatacttcca cccaccgttt caaacaggct
     2041 accaggaata ctaaaccagc tgcttgcctt aaaagcattc aaacctgcgc tggctgtgat
     2101 gttcagcgca gggtacatat ttgcgcgcgc tacgccggta cgggcgttgg cggccataac
     2161 agacatctca gcggcatgta cgtccgggcg cgcactaagc agggcggccg gtacaccggc
     2221 ggataactgt ccgtcgaaac gcacggattg caggtttgcc tgccgcgcga tgctgccggg
     2281 aagatcgccg gtgagcagtc gcagggcatt ttcctgctga ctgatctgct gttcaatctt
     2341 gggcagcaac gcagcagcgg cgtcgcgctg ggcttccgtc tgttctattg ctaatgtgtt
     2401 tgtttgtccg gattcatact gcaggcgcat gatacgcagt gtactgtcgt tcagcgccag
     2461 gttcttcttc gttatctcca gctggttgtc cagcatgagc aggttataat acccctgcgc
     2521 cacatcgctt accagttttg tctgcaccgc tttggaggct tcggcactac gcaggtaatc
     2581 cgccagcgcg gcttctttca gcctgctgat cttaccccag gcaatcactt cccaggacaa
     2641 tcctacgttg gcgttatagt catccatgaa cctggtgccg ataaattcct gcgacaagga
     2701 gccgttcaga ctgtttttag acggccagtt acggttaccc tgtactgtca ggttgatatc
     2761 cggcaggtta cctaacctgg acgcacgtac gcttctttct gccgcttcca catttttcag
     2821 ggctgtcagc atatcgaagt ttttcgcaat ggcgctgtct atcagcgttt gcagcaccgg
     2881 atctgtaaag aatgatttcc aggggatgcc ggcaatactg gtggtatccg tggccgcacc
     2941 ggcgccgcgg tacttatccg gtaatgctac tgccggcctg gtgaagtctt tacccacccg
     3001 gcaggccgtc gtcacacaga tgacggccat taccaggatg agtgatattt tttctttcat
     3061 aaaaaatact gatttaagaa gatgattaag catgtacttc ttctgctact gcatgttctg
     3121 ccggcttttt accggttact ttttcctgca ggaactggaa aacaataaac agcaccggta
     3181 tgataaatac ccccagtata acacctgtga gcataccgcc ggcggtgcct atactgatgg
     3241 aaacgttccc catggctgac ggacctttta cggacatcag cgggatcagc cccaccacga
     3301 aggccagcga tgtcatgatg ataggacgga gccttagccg ggctgcctcc agtgcggcag
     3361 acaacaacgt tctgcctgcc ctgcggcgct gtacggcaaa ttccacaatc aggatcgcgt
     3421 tcttggccag caaaccaatc agcattacca gccccacctg cacgtaaata ttattgtcta
     3481 tacccaccat gttgatggcg aggaatacgc ctatcaaccc cgtcgggatg gacagcaata
     3541 ctgccagcgg aagaatatag ctctcatact gcgctgccag caggaagtat acgaatacaa
     3601 tcgccagcgc gaagatgagt accatctgat tgccggaatt tttctcttcc ttacttaaac
     3661 cggtccattc gaaactgaag ccagccggca attttgtagc tgccacccgc tctaccgcct
     3721 gcatagcctg accggtactg tatcccggtt taggcatcgc gttcaccgca atggcgttga
     3781 acagattata gcggttcatc atctccggac catatacttt tttcagggta acgatgctgt
     3841 tgacaggcac catttctccc tgttcattct ttacaaatac cccttccatg ctggcggcat
     3901 cgctgcggtc ttccggcgca gcctgcacca tcacacggta atatttaccg aaacggttaa
     3961 agtccgatgc ctggttactg ccgtaatagg tctgcagcgt catcatcagg tcactcacac
     4021 tcacgcctaa ttgtttggct tttaccgcat ccacctgtac ttcaaactgc gggaagtccg
     4081 ccttgaacat ggtgaacgcc acccctattt cagggcactg catcagttcc ccgatgaagt
     4141 tattggccgt ttcgctgaag ttctgcacag agccgccggt gcggtcctgc aacatcagct
     4201 ccagcccgtt gaaggaacca aatcccggca cggtagggaa agtgaatacg ctgaaagtac
     4261 cttccttaat ggtgctcagc ctttctgtca tcaccgccac tacgtgatca atctgctgta
     4321 cttctcctct gtccttaata tctttcagtt tcacgaaacc catcgcatag gcagggctgg
     4381 cggcattact caggatgtta taaccggaga tgctggtgcc ggaaactacc atgggcatgg
     4441 ttttcaatac gctgtctgct ttctccaggg ctttggtggt acgttccagg cctgctcccg
     4501 gagggagaga cagggaccat gccacgaagt tgccgtcttc attggggata aaccctttcg
     4561 gtgttacccg catcaggtat accactgctg cgatgatcac cgcgagggaa cccagactga
     4621 cccatttgta gctgatcagc catttgatga tgcgcgtata gcggtaggtc atcgcctgga
     4681 aaccggtgtt gaaagcggtg aaaaagcggc ggccaaaacc tttcttcgta tgaccgttac
     4741 tgttttcatt atcaccttca gcggtgtggg ggttcttcag aaacaatgca cataaggccg
     4801 ggctcagggt cagcgcgttc agcgctgaaa tcaggatggc gatagccagc gtaaaggcaa
     4861 actgccggta gaatacgccg gtagggcctt ccatgaaacc taccgggagg aatactgccg
     4921 ccatcaccag ggtaatggag ataatggcgc cggtaatttc gctcatagca gataaagtgg
     4981 cggctttggc aggcagatgc gagcgttcca tcttactgtg cactgcctcc accaccacaa
     5041 tagcgtcgtc caccacaata ccaatggcca gtaccagggc aaacagcgtc agcatattca
     5101 ccgaaaagcc catcagctgc aggaaaaaga aagttcctat cagcgatacc ggtacggcta
     5161 tcgcggggat cagggttgac cggaaatcct gcaggaacag gaatacgatc acaaatacaa
     5221 ggatgaatgc ctctatcagc gtggatttca cctgcgcaat ggaggtatcc agctgttctt
     5281 tggtactcat cgttatctgg taacggatac ctttggggaa tgtcttctgg gcattttcca
     5341 tcacctcctt tacagtggtc tgtatcgcat tggcgttgga gccattggtc tggaaaacgg
     5401 ccatggttac ggcatcctga ccgtttacgc ggttatccgt tgcataggtg gcgcttccca
     5461 gttctatgcg ggccaggtcc ttcaggaata atacagagcc atccggggct acgcgtacta
     5521 caatattttc aaactgctcc ggtgtattga acttaccgct gtaattgata acataggaca
     5581 aggcagcatc cgtgccctct ccgaatttac cgggagcagc ttccaggctc tggtcacgga
     5641 tggcgttcat cacctctgca ggcgttacct tatacgctgc cagtgcagca ggtttcagcc
     5701 atacgcgcat ggagtagtcc ttaccgccga acacctgcac ctgccctact ccggagatac
     5761 gtttcagctc agggatcacg ttgatcttgg caaagttctg caggaaggct tcgtcatatt
     5821 ttttctggtc cccgctcaca atgtcgagga tcataatcat accattctgc tgcttggtgg
     5881 tagtaatacc tgcctgtact acttccggcg gcagggtact ggttacctgg gccacgcggt
     5941 tctgtacgtt caccgccgcc tggtcagggt ctgtacccag tttaaaaaac acggagatag
     6001 aggcactgcc gtcgttgctg gcagtggatt gtacgtaggt catgttctcc accccgttga
     6061 tggcctcttc cagcggcgta actaccgaac gtaataccgt tgcggcgtta ccacccggga
     6121 agctggcgct caccataaca ctgggaggag caatatcggg gaactgtgtc accggcagcc
     6181 gggtaagtcc taccaccccc agtatcacca ggatgacgga tattaccgtt gccagtacag
     6241 gtctttgtat aattttcttt aacatagtca gaattcgttt aagcgcttat tttgcttttg
     6301 cggcagcgga atctttaggg gctgcagccg gcgttactac ggcgccttcc atcagtgttt
     6361 caatccctgc tgtcacaatc ttgtctccgc gtttcaatcc tccctttacc aggaagttat
     6421 tgtcgctgct gccggcgata tctatgatct ggcgttttac tttattgctg tcacccagct
     6481 gatacacaaa caccttgttc tgcatctcca gggtagcggc ctgcggtacc agcagtacgc
     6541 cggaattcag cgtctctatc tttaccttgc cggtattacc ggaacgcagt acggaggagg
     6601 ggttcgggaa agtggcccgc agactgatag ctgctgtggc tttgttgaac tgcccgtcta
     6661 ccatttcaat gcggccggta tgcgtatagt cggtaccgtt agacagcacc agcgttacgg
     6721 ggcgcagctg ttttatctgc tgggataaat tacctgcggc gccgccatgg ctgaaatcca
     6781 tgaaatcatt ttcactcatg gagaagtagg catatacctc gctgatatcg gaaagggtcg
     6841 tcagcggcga agcgtctgtt tttcctacca ggttacctat tcttttggga atacggccta
     6901 tatagccgct caccggcgct tttacaacgg tgaagcccat attgatccgg gaggctgcaa
     6961 cagccgcttt ggcctgttcc acattggctt tcgccgtctg tacggtagcc tgcgctgttt
     7021 tcagttgtat acctgcaacc accttgtttt ctaccagcgg ccggattttt tcggcttcca
     7081 gttcggcagc ggccagtgcg gactccatcg catgcaggct ggcgatgtcc ttgttaagct
     7141 gctcccggta aggctggtcg ttaataccaa acaacggctg acctgccttt acgtaactgc
     7201 cttcttccac ataaatttta tcgagatagc catctacctg cggacgcacg tccacattta
     7261 cctttccttc cagctgggca gcataggctt tggtagtcat agcggtagta gtatccaggg
     7321 tcgcaacggg caactcctgg ggaggcatgg cttctgcgcc cgcagcagct ccggcattac
     7381 cgccacaacc ggtaatacca gctgccagca tgcccagcag cgctaatccg caaatggttc
     7441 ccctgcgtcc tcctgtatgt aataactgtt tcattacgat gagaaatttt taacctatga
     7501 gaagcaaata tcgcttccat taaaaagagg tatggcacaa ttccctacga aacggaaata
     7561 acaggagctg aaacggataa ataacagggt gaattattta agatttgatt atttggctat
     7621 ttgagatttg attatttgaa atgcagcgaa gattaccagg aaaagaatac tgaaatcgtc
     7681 ctggtaatct tcgctgcatt tcaaataatc aaatctcaaa taatcaaata accaaatatt
     7741 ggtggtttga aattattgtt ttaaaattgc aacaatgttt caaaaattat tcacacggaa
     7801 aaagttcccc ttctataaac agtcagatgg tatggactgc ggaccaacct gtctgaaaat
     7861 gattgcggaa cattacggcc ggaagtttcc gctgcagtac ctgcgcaaca tcagcaagct
     7921 gacgcggcaa ggggttacca tggcggatct ggaggcaacg gcggaacagc tgggatttaa
     7981 tacgctgccc gcctcgctgc atatacaggt attgacggat aaagcaccgc tgccctgtat
     8041 tttacattgg gagaaacagc actttgtggt gttgtacgat ataacaaaaa cgcacgcatt
     8101 catcgcagac cccgcattgg gaaagcctgt cagctatccg ctggccgatt tcctcgcggc
     8161 atgggaacag gagccgggca gccgtaccgg cagggcattg ctgctggaaa aaaccgggcg
     8221 cttcaatgaa ggggaagccg taccggataa agatgtccgc ctctggtcat tgttgccctg
     8281 gcttcgtccc catacccgcc gcctgcccgc tgtggccggc accctcctgc tcgccagcgc
     8341 gtgctccctg ctgacaccgc tgctcacgca acgtattgtg gatacggcta tcaccggcaa
     8401 gaacctgccg ctgctgctcc tcatctgcac agggctgctg ctgctgttta ccggccgcac
     8461 cctgatggac ttcatccgcg cacgcgtgct ttacaaagcc ggcgctctca tcagcataca
     8521 attgctgaaa gcctacctgg aaaagctgat gcgcctgccg ctcgctttct ttgacaatcg
     8581 ccacgcgggc gataatatgc aacgggtaac agacaaccag cgggtagaag acttcctgac
     8641 atcctccctc gtaaatttca tgctgtctgt catcaccatt gcagtacttg gcggcgcgct
     8701 gctatggtac aatacatgga ttttcctgct gttccttaca agtgcggcgg tcagcgtact
     8761 atgggccaac tccttccagg aaaaacgccg catcctcgat cagaagaaat tcaggatact
     8821 gtctgccaac cagcacatac tcctcgaaat attctccgcc atgcaggaaa taaaactcac
     8881 cggcagcgaa catctcaaaa gcacacagtg ggaagccctg caggataaat cgctggcgct
     8941 gaagctggac agcctgcgca tggaccagtt catgcagggc accggcgcat tcatcaacga
     9001 aatcaaaaat atactcatca ccggcgtggc cgctatgctg gtaatagaag gccagattac
     9061 gctgggcgcc atgctcgcca ttacctttat ctgcgggcag ctcaacgcgc cggtactgca
     9121 actggcagag ttcatccgtg tttcacagaa tacccgcttc agtctgcaac ggatggagga
     9181 agtacagcaa gaacctgatg aagatccgcc gcaggcagca cccttcccgg atataacgga
     9241 aaaggatata cggctgcgca acctctgctt ccagtacgga cataaacatt ctcctatggt
     9301 gctgcaacat gtcagcctgg tgatacctgc cggtaaagtg accgctattg tcggtatgag
     9361 cggcagcgga aaaacgaccc tgctcaaact gctgctccgc tgttatgcac cggtatccgg
     9421 tcagatcctg gtaggcacag taccgctgca aagcctgcct gccagagagt ggcgcagaca
     9481 ttgcggcgta gttatgcagg atgggtacat ctttatggat actatcgcca ataacatcta
     9541 tgccggcgca cagatcaggg atgaatccag gatgttccgc gcagctgaaa tggcctgtat
     9601 ccacgacttc ttcagcagca tgcctttcgg atacgaaacc atggtgggga aagacggata
     9661 cggcctgagc gaaggccaga cccagcggct gctgatagcg cggctgatct accgtaaccc
     9721 gtccttcatc ttcctggatg aagccaccaa ttcactcgat gcgcataacg aacgcgccat
     9781 catcgggaac cttcaccagt tcttccccgg aaaaacggtg gtggtagtag cccatcgtct
     9841 cagcactgtt aaacacgccg atcagatcgt agtcatggac aagggccaga ttgtggaacg
     9901 cggtacccat gcggcacttg cagccagtaa cggcgcctat taccagctga taaaaaacca
     9961 gcttgaactg gggaagtaat cactttgtaa acccatcacc atgccagtaa acatttttcc
    10021 gtatacgctt acccgttata gtactattca tcaccgggac ttccgcccgc tgacactacc
    10081 cggcattcgc cggcagctgt ggctgcagca gcgcaccggc gaactggtga tcgccggccg
    10141 cgaagcgctc tgtgaaggcc tgtttcacct catccgggaa caggaagacg atagcctccg
    10201 gaaacaactg ataaaactta aaagggaact gcagcaggat aagctaccgg cacagcttcc
    10261 acccggatta ccggcagctt tgcaagtaca gctggaaagc cagctacggc tgctgctacg
    10321 ccgccagtca ctgcctgcct cctggcaggc atactacgac cgccgcctgc agcaataccg
    10381 gcagcagctg cagcaatgga cccgcaatcc actactgctg aacggcctgc tgttatccag
    10441 ccccgtactg tacgaacagc tgcccgccta taccactgca catcccgctg ctttcaggca
    10501 taaggaactg aaaatagagt atagcctcct gcgttatatc acacgcatgg catttaaaac
    10561 ctctcccttc agcaccttta cctatacggg gcttaccgcc gttacagcag aagcggcaac
    10621 taccgcaccg cctgccatga gccacagcag catccggctc aacaacaccc tgtttactac
    10681 cctgcaatcg ctgatgctac agcatccgtt actgaatgaa gccctgtacc tccggctgaa
    10741 cagctccatc gccagggaaa acggacagct gctgttcctg gtcaactgct ttaatataga
    10801 atctttccag cgcatgcccg atagcggcat tatgcaatgg ctgtacgcat ttatcacgaa
    10861 cagcagggaa agggtaagtc tgcagacggt aacagatgca ttacatgcta aactagcgga
    10921 tacagacagg gatactgtaa aggcatacct cctgaaactg gtgagcagcg gcctgctgga
    10981 agcagttacc ggctgctctg ccgttcaccc gcaatgggaa gaacagctgc tgcagttctg
    11041 ccgggataac ctggcagtgc ataccgccct gttgcccgtt catgagttat tacagcaatt
    11101 attcacttcg cgccgggatt acgtatatgc atcaccggca gacaggtacc ggttgctgca
    11161 ggacgctgcc acactgatta atcagtcact ggaaaccctc tatgccgtac ctgaactggc
    11221 ggccgccctt gccgcaccgg aaagtgctgc tgctaaaatc agggagtccg gcgcttttgt
    11281 taccgacatg tttgcccgca gaaatttttc tcctgccggt attttttatg aagatgctgc
    11341 tgccaccggc atcggtcatc tcccggcggc agacatccac gctttcacgg caaccctgga
    11401 aaagctcttc cagtcgctta ccccgctgga tgacctgcag gaagaacgaa ccagcatgcg
    11461 cgatttcttt ctgaaacatt atgaaccgga tgaacagatt gctgtaacca ccttctatca
    11521 tcagtattat ctggaagaaa aaaaagtaag aaaaacgcag cagggagaca ggtccctgct
    11581 cccagtctcc gaagcaacaa agcaacgtct ggaatcctta ctggatacac atttcagcaa
    11641 tgcgttccat gctgaaatca gcgcccgtga agtagcactg ccggacaggc gccatgcagg
    11701 agcggcgttc gtgcagtttt accggggccc cgcaggcctg acaggtgtgg taaacaacct
    11761 gctgcccggc atgggaaaag tagccggccg cttcctggat ctgttcgatc cttcgctggc
    11821 agcgcagttt tgtgactgga accaggccct ataccccgat catatgctga tggagctgag
    11881 cgatggttcc agtttcaatg ccaatataca cctgccgttg ctgccttttg aaatagctgt
    11941 tcccggcgga tacaacaact atccggcgga acagcgtgcc cggctgcagg atgtactggt
    12001 cagatatgac gaagcctcgc agcagctctg gctgcagcat gcgccggatc aacgccgcat
    12061 cttcgcctat gatctctgcc tggaatcctt ttatctgcgc tccaattttt atcagctgct
    12121 ggcacatttt aacccggagc cttatctgcc gcttaaaaaa ttcttccggc tgacagatga
    12181 tgcccatgca accgcttttc cggagcaagg gcatatccgt ccgcgcatca cttttgaaag
    12241 caaggtggta ctgcgcagaa tgggctggct cgtacaaacg gctgacatac cgcagcagca
    12301 gacagcagaa acggaggccg cctggttcct gcgtgtacag caatggcggg aacagcaagg
    12361 cattccggag caggtattcc tgttcctccg ctcccgctac agcaaagcgg ataaggactc
    12421 tccttctgca ctgcagcggg atgattacaa gccgcagtac ctgcatttcg ggcaaccttt
    12481 gctgatgggt ttacttaaaa aactactggc ccgcgccggt acacagatat acctggaaga
    12541 gatgctgccg cataccagtg acctgcagca ggagccggta acagaacaat tattgcactg
    12601 gtataattac ggaacatgaa gcatccatcc aacagctggt ctgcagccaa ccgctctgcc
    12661 ttgcccaata cgggaacggc ctggctctcc gcgcatattt actcccgcgg cccgctggac
    12721 cggctgataa atctgctggc cgctcctttc accgccacgg tagccgcctg tctgcatcct
    12781 gtaagtcctt tcttctttat acgctatggc gaaggaggcc cccatatacg gttacggcta
    12841 cacgtcaaca catcgcacac agaaacggtg cggcatatgc taaaagaagc tgccggaaac
    12901 tatttcagcg aatatccctc agtgccggtc agcggaggcg aaatgcccct ccatgatacg
    12961 ctggctttta tgcactacca acaggagaca gcacgctacg gcaaccagca cacgatcccg
    13021 ctggccgaag aacagtttta cctgtcttcc cggctggtga tggaacagct gcagaacgga
    13081 gctgcagcag catccctgac atacggtatt caactgcacc tttgcttttt catggccatg
    13141 cagaccaccc tggcagatat tcagcgcata tgtacccgtt tcatccaggc ctggtcgcca
    13201 tcattagcag gttccatgaa cactcctgag caggcagccc tgataaatac gcatatggaa
    13261 aatatgtacc ggcaatacgc accttcccta cttcctgcca gcgaaacgct ctggcagcaa
    13321 ctgaagcagg gaaaggcacc gccggcgctg caatccttta cctaccgtaa cagccgcctg
    13381 ctgcaacggt attatcacgc cggattagct gccgggcaac tggaagaagc cttctgcagc
    13441 atgatgcata tgtcacacaa cagactgggc atctccaatg cagaagaatc ctggtgcgtt
    13501 tttcttaccc tgaaatgtat ttcccacctg tatgagtatg accgctgacc atcaacgtat
    13561 aaacgatgcc gttatgagta ccgccgcgcg gctgctgcag gcagcacagg aggatgaaca
    13621 cggtatttac tggatcactc ctccgcatat acagggcggc gcgccgggag aaagcacgga
    13681 cctttttaac ggcactaccg gcatactctt cttctttcta tccctgtatg attataccgg
    13741 cgaggccgca tatctgcgcg tatgtatacg gggaaccgcc cggctgctgc aacatccgga
    13801 aatccggcag ccggccttct atcctttcta taccggcgcc accggtatat tactgctgtg
    13861 catccggatg caccgctata ccggcaacag cgattacctg gaacaggcgc tgctgctaac
    13921 gtacagctat cagcaaggta ttctgcagga agtaaaaaaa gatgacctgc tcagcggtga
    13981 tgccggcaac ctgctgctgt tcacacatct ctacgcctat acgcagcatc cctgctacct
    14041 ggagataatg cggcagctta ttgaccagct gctgagtcat gcccgtatag cgcccgccgg
    14101 tctgaagtgg gacccggtaa aacaggcata cgacagcctg acgggatttt ctcacggcgg
    14161 ctccggcatt gcctttgccc tgctgcaggc tgcgcgctgc ctgcatagcg atggattact
    14221 atacctggca gaacaggcgc ttgcctatga aaatacttac gcggaccccg cccgcaacaa
    14281 ctggatggat ttacgtacag gcgttaaaag aatgcaacag ctggcagata cccagggagc
    14341 ggctatattg aagtgggagc tgacgccttt cctggccggc atgagccatc ttaatacctg
    14401 ggcgcacggc gccgccggca tcggcatcgc gcggctgcat atctgggaac atacgcacca
    14461 cccggcctac atggcagata ttcaacaggc actccgccgc tgcctggcag atgcagcagc
    14521 agataaccgc ggcgactata cgctctgcag cggctatggc ggcatagccg ctttcctggt
    14581 ggaggccgcc cgtatattga aacaaccata ccttacggct gcagcacaac gtatagcaat
    14641 tgcagccatt gattattccg aaaaacatca cacctataac agccacctca taacagatcc
    14701 ggaagatccc ggactccttt ccggactggc tggcgcaggc tatttcctgc tgagcaccat
    14761 acatgcgccc ggcccggatt ccatcctgca ccctgctatc aataccgaaa acactgaaat
    14821 taacgtaaac gcatatacgt taaatgaaat aaaggaaaaa ttattcagca gatattatcc
    14881 ccgcacctgg cagacattga cgcaggatga aaccattgcc ggcatcttac tacaggcccg
    14941 ggatataccg ggattacgga ttttgctacg ggaacaaatt atccggcacc cggatgcgcg
    15001 ctccctgttt cttaatgaag acaccgcaac ggatctctgg ctgcagcaca aaggatggct
    15061 gcaacaccgc gaatgccggc gcttacaaca acagctcata caacaagtaa cggaacaccg
    15121 gctattggta atcagccggc atgtgaaagt atgtggtcag gtaatctggt acagtcatga
    15181 tacgggcatc aatagtactt ctgcgggtaa actgactgct gtgatactgg aatggctggc
    15241 tactcccatg agtatgatac agctacagga acagctcatg cagacacagc caccgggtac
    15301 acccgatgcg gtggcataca acatcattac cgcacaggta aacgagctgc tgcaatgcgg
    15361 cttcattacc cctgcatgag ttaacgccag ttgttactgc gcaccttggc agataatgcc
    15421 tctacttcct gcggatcgcc ggggaaccgg tatatatcca ccggatcaca gaatccggtg
    15481 atggtatttt caaactcctt cagctcttcc tgcacctgtt cactcagacc cgcagcatga
    15541 tgctcaaaga tatcccggag caccgcaaac acttcccttc ttccccaccc cgcaccaatg
    15601 ccctcatcta tcttccggga aaatctcaac caccggtcat cctcagcatt atccccttcc
    15661 agcaccgata aaatatcctt ctttaacgcc tcctgtttca tacccccaaa ataacatttt
    15721 ttattttttt atttggttat ttggttattt gagattttac ctgcacggat tattattact
    15781 attcttttct ccggcaaaag gaatatcatg cataccacaa atctcaaata aaaaaataaa
    15841 aaaataaaag cgggccttgc ggcccgcttt atcttctctg caatctggat ttgcgtcaat
    15901 ccgggattag caaatctgtg ttgtacagaa atgtccttca tcatctgtac gctctgtgtg
    15961 cgtagggtgt gcctgggcag ccaggccacc tgccagacgc atgctcattt cgctgtcaat
    16021 gctggttaca aagctttcaa ttttcagatc ttccaggctc agttttaagt tgcttacatt
    16081 gttttctttc ataaaatagt atttaattga ttagatgcct actattatga gggtttcggc
    16141 attccccgga ttgcaatcca tataaagata taaaaatgaa acattgttgc aaaaattaaa
    16201 agcacttttt ttcagttttt tttcaccacc tgattcctgc gaaagccttg aaattaatgg
    16261 gtgttccatc gatgtaataa gttgttttca catcaggata aacagatccg atcagtatat
    16321 ctccgctgga gaaataacgt ctgttcgtaa tattctccgc tacaatccgc acataccatt
    16381 tacctgcatc ccatgatgcg cctgcatcaa agagcgtata atcaggcagg tacaaatcag
    16441 gcgtataggt gccgggccgg atagcagtac gctgtcccag gctcagccgc aaccgggcgg
    16501 tgctgacagg aatactgtac tgcaaccatg tattgatatt ctgctgcggc atgaacggca
    16561 acgccgtacc tacattagct ggtttggtat ccttactgat aactgcgtcc gtataggaat
    16621 aattggcaga aaccgtgaaa cggtcggtta tctgccccat gacatccact tccacaccgg
    16681 tactctttac ctgcccgatc tgtttgcgga agcggcgatg ctccggatca gctaccagca
    16741 tattattctt gataatccgg taaccggtaa cagtagtact taaccgttta ttgaaccaat
    16801 cgcctttcac acccagctca aaatcatttc ccagcaaggg tttgaacagg ttcttatcga
    16861 agtcggatcc tgtctgcggt ataaacgact ggtcgtacaa tgcatacaca gaaagattgc
    16921 tccgcagcag ccaggtaata cccagcctgg gcgaaaacgc ctgctgcaac tcttttcccg
    16981 gtcttgtatt ccgggtgtac ctgcctccga tattaatacg ccatgcttcc ccgacgtgaa
    17041 tcatatcata ggcataggcg gatgcccagt tgttctcatc cacctgatcg gcagcagctt
    17101 tcagcatacg cacactatcc gtatgcaatc catacaccgg ctgccttctg tcaaaataaa
    17161 aactgtactg cccggtggtg taattgtaca catccctggc atagttaaaa tcaacaccgg
    17221 tcatcaggta atgacgtata gccgttcccg tattgaaaac acctttgaca tacagttgcg
    17281 atgccactac ctgcccggta gaatgattcc gcaccgggag tctgcgggtg gtatcattga
    17341 taaagttcac cggcgactga ttcgctgaaa acagatacca tgtttcggct ggcgtggagg
    17401 tataacgccc ctgtgctacc agcttccagc ttttgcttaa cgcatggtta aacaaaaagc
    17461 ggacagactg cgtttcgccg taggagccgg gcaatcccgg atctccggca aaattatctg
    17521 ctatacgcgc atgcctgatt tcttcgtccg tacctacctt gttcaggccg ctgccgccgg
    17581 ccgacgaagc acgcagcagg ttatattcca gcagcacgga ggtacgcggc gaaaaattat
    17641 actgtaccac aggcgccagc acatattttt ttgtttgaag aaagtccagg aaggaacgtt
    17701 cctgctgata ggcagcattc attctccagg agaaaccctt cgtctttatc atgcttccca
    17761 ggtcaacgga agcccgccac ataccgaaac tgccgccggc tatctccaca ctccgcacac
    17821 ggcgctgcag cggcactttg gtggtaatgt tcactgttcc tcccggctcg ccggcagacg
    17881 caagaaaacc tgccgggcct ttgataaatt ccacctgctc aataatagca gcatcgtcaa
    17941 tggtggtccg ttgcagtaaa ccgttcacat aggtgggcgc aggaaagcca cggataaaaa
    18001 tggtggcaga tccgtcgaat aaattcgtgt tgtagcccat gtgtacgccg cttgcatttc
    18061 tgacaatgtc tttcatcacc agtcctccct gttcagctac cagcgcgctg ctcacgctga
    18121 cgatattctg cggtgtttct ataaggctgc cttccaggcg cagaccagcc ggaatactat
    18181 ctgcgcgcag gcgcttcttt ttttcctgca cctctacctc gcgcagccgc atcctgcgga
    18241 tactgtctgg ctgctgctgc gcacagacgg acgacgccat tatcaggaac agtaacagga
    18301 agcgtacttc ttttttcata tagtcattac gtttataggt tatagttgga tattacgccg
    18361 gccggctatc acacagccgg ctgcgagcag gacgattcct gcggctgtca ggtataaaat
    18421 gccttttccg atcatccttc cggcatcagg gtcgccagct ggctgatatt tcggaatggt
    18481 ggcatatgct gcagcggtaa actgccggtt gttaaaataa aatccgtaga aataatgctt
    18541 ccattgttcc cggaaagcgg ttacctgctg ccggaaatag taatcgtcag taatgtctgt
    18601 atgcgcaata cggctgtata acgcctgcgc atatacggca gggctccatg cataggccgc
    18661 agttactcct gccagctgtt gctgccggcg ttgctgctgc ggggccagga tgcggtccat
    18721 ccgttgttct gccagctgat aataggccat ggaacggcgc atgcttcctt cgcttgtatc
    18781 ataggccagg tgattgcggt actgcggata tacctgatag aaactgtcca gcagctgccg
    18841 ctgcggcagc tcccaggtat cccaggcaat atcccgctgc cgcgaggcat tggtagcagt
    18901 atcatcggta acacccgtat cgctgatcct gaagtgaatg acagccggca taacgaccag
    18961 cagcagcaac cagcagctga ggagtgcaat gaggttcacg cccgatgatt ttccccaggt
    19021 ggtcaccacc cagcagacgc ctgcccagaa cagcgtatag gcggccgtta ccgctatcca
    19081 cgcccacact tcacctgcat tcaccgggat accggccggc agaaaaataa tccccgccag
    19141 gattaaaaat gttaccagca gcagcagcaa tacccatcgg atacacaggc gcatgagcaa
    19201 tattcttctg aaactaccct gttgaataat cagcagtttc agggttccct gttcctgctc
    19261 ctgagaaaac aggttatagg tgagcgcaat gagcatcagc ggcagcaggt agatgcagac
    19321 aaaagccagg tcaaaattac cggtcatcag ttgctgcgga ttactcagct tctcttctgc
    19381 gggcgtataa ccggcattga tcttcaccgg gtaataatgg cgcgccacat cgctcatacc
    19441 tattgccagc accgacatag cgcccggcag ctgtaccgcg ttgttgtaca gcctgtattc
    19501 aactacagcc ggctcaatgg cagcctgata gttctgttta ccttgctccg tagctgtatc
    19561 cgcccgtaag gaagtataca tggcggtata cctttcggta tactggcgct gcatactatc
    19621 tataccggct acacgctgct gagttacatg atgcccataa aacagcgcac agctgccggc
    19681 agccaggcaa acggctgtca gcaccggcaa tactgccgtg cggaacaggg cgcgtagttc
    19741 tgaagcaatt atctgtatac tgtatctcat cgtgtatgac tgcactttat tgatgaatta
    19801 tcctgctgat tcctgccggg ataactttcc cagcaagagc aaacctgctg ttacccatat
    19861 cagcagggag atgcctgcca gatactgctg ccgcagtatc tccccggtgc cgggaggcgt
    19921 gtacctgaat accggcatct gtttaaaaaa tgtggcatct gccttccagg agtagtcgcc
    19981 cgttttgctg ccaccataag ccatttcatg attcagggcc gcgatgaaat cattcctgta
    20041 gcggcgggca gcggcaaaaa aatgcgcatg atgcatatag tcagccccgc ataaggccat
    20101 agacagctcc ctgatagcca ggtaagggtc cagcagtacg gcgtaggccg taatgctatg
    20161 ctgtaaacgg atgatactgt ctatatgcct cgtctgatct tcgtatatgc gttgcatata
    20221 gtcctctgct gcctgcatca ggatggcatc gaagttaaca ggcagttcgg ccgtggtttt
    20281 cacctggtat tgtttcagcc agcgtgcttc cagctgctgc tgccgttgca cccgcggctc
    20341 gtcgccgtgg atgcctgact tctccgcacg ggaaatattt tcctgtacaa ccgactgcgc
    20401 cggcaaagga tacagcatat ctcctgctgc cgcagtcatc ctgggcaata tcaccacggc
    20461 gaacaaccat cccgcgagca ggagcagtaa cgcctggttg ctgcgcttca gcaatacaga
    20521 tgccgccatg catagcagcg caatgacaga ggcatagagc atataagcta tcgtgagcag
    20581 cagcgcctgc acggagatag cagacgttat accgccgcgc cagaaaaata aagcaggcaa
    20641 cagcaagagc agacatgcca gcagcaatcc gttagagagt aacagggcca atccggcctt
    20701 tgcccttacc agtacgcctc gtgcgccacc ctgtatcagc agcagcttca gtgtacctgc
    20761 ttctctttcc tgcacatata actggtaaca gcagaagatg atgaccagcg ggaagaacag
    20821 ctgtaatact gctgccggtg taaatgcgcc gaagcgcaga tagttgtcgg ccggctgcac
    20881 cggggctgct gccggcatat gctgtacatg cgcctctaca cgcatcgtat agccgctaac
    20941 gtgatggata ccattatcaa agctgctcag caccgacagc ggcttgtaca gccaggtacc
    21001 gaagtgcgcc gcatcatgcg gattaccggc acggagctgg tcccattgtg cgcggaacag
    21061 ggaatctgct gcaagacgct gcgtctgcaa ctgtgcatcc tgctgcagtg tgccggtgaa
    21121 agcgatacca cacatcagca gcagcaacag gcatcctgcc agccaggtgc ggttacggca
    21181 catggtctgc cagtctttgg cgacaataat tttatacata agttatcggg cggcggtcat
    21241 atgttccata taaatacttt ccagggcata gtgatctaca tctgcagcat ccatcacggt
    21301 gagcagccgg ccatgcttca tgatgccgat gcgggaagcc acttcccgcg cacggtacag
    21361 atcatgtgtt gccataagca ccgcacggcc ttcattactg aagcgttgca gcaatacgga
    21421 aaattcattg ctcgctgccg ggtccagtcc ggacgtaggt tcatccagca gcaatacagc
    21481 cgcctgcttt gccgtggcaa tggcaatacc tactttctgc cgcatacctt tggaatatcc
    21541 acctacacgg cgatgcacgg catcttcctg taagccggca cgcagcaggt attccagcag
    21601 ctcctgccgg ctatgatgca taccggtgag cgcatgaaag aagaccaggt tttccagtcc
    21661 gctgagatag ggatacagca tcaccgtttc agggatatag gcgatatgct tcctggcctg
    21721 ctcccggtgc tgctgcacat taataccgtt aacgagcgcc tgcccgctgt ctggctgcac
    21781 aaatccgaga aagcagttga tagtcgtggt tttccctgcg ccgtttggtc ccagcaaaca
    21841 gaaaatttca cccggaccaa catgcagatc cagcgcgcac agcgctttat gctgcccgaa
    21901 ctgacgggtc agcgcaatag cttgtagcat agcttttcct taaaggattc actgataaaa
    21961 aacagatgca ataaaaggtg ggctatacaa caggagggcc cttgttggcg cagtggagaa
    22021 tgattgcctg tggcggagta atatgcaggg acgcatatgc caccatccag gagggttgta
    22081 ataacaagga gggtttcaca gatggctgcc acacctcttt cgccagctga taatcacaga
    22141 tggcgcaata atgtgcagca acagatatcg tacatcccga aggattatgc tgctgaaaaa
    22201 tacgcatccc ttccttccct gcatagtcat gccggtgcgt cgtttttaca gcctgtataa
    22261 ataccagtac agccagtaaa aagaacgcac acagccgagg ccacacatta tgtccgggtt
    22321 gcttcataaa agcaaatata agggaagttc cgaattatga aaccaagttg catttttatt
    22381 tttttatttg attatttgag atttggttat ttaaaatgca gcggagattt cagcatatat
    22441 catcatcgcc aaaatctccg ctgcatttta aatagccaaa tctcaaataa tcaaataaaa
    22501 aaataattac aggttttgtc cgccggaaac ttcgatgcgt tgcgcattga tccagcgggc
    22561 atcttcggta cagagaaagg ctactacgcc gccgatatca tcgggaaggc cgacacggcc
    22621 cagtgaaata gtggatgcaa tgagctggtt gacgtgctcg ttatctctga cgaggccgcc
    22681 gccgaaatcg gtagcgatgg cgccgggagc cactacgtta acggctatac cgcgttcgcc
    22741 gagttctttg gccatgtacc gggacaatac ttccacaccg cctttcatgg ctgcataggc
    22801 gctgtagccg ggcaatgcaa aacgtgccag accggtagaa agatttacga tacggccacc
    22861 gttgttcagc cagggtaaag ccttctgtgt caggaagaat actcctttca gatgtatgtt
    22921 caccagcata tcgaaatcat cttccgttgt ggaagcaaat ggtgcgtgca cacctacgcc
    22981 ggcattattc accaggaaat caaaatgatc tgccttaaaa tgtgaagtca gcagttgtcc
    23041 cagttgctga aagaaagcgt caaacgtttt tatgtcgccg gtattcagct gcagggcggc
    23101 agctttgcgg cctgactgct caatagctgc tactacggca tctgcatctt cttttctgct
    23161 gttataggta atgactacat ctataccttt tgcagcaagg ctaagcgcca tattttttcc
    23221 gagtccgcgg ctaccaccag taaccagtgc gattttacct gttgtcattt tttccttttt
    23281 ttgatgttac aggatgatga tgccatcatt ccaactgata tcacaaaggt aaaacgggat
    23341 atggagcagg ccgttgcgca catcaatccg atgtttgcaa aattcaaaca tctcaggaac
    23401 ggaaggccac gggagacaaa gtagtttgtt tacggaagaa gttagaaaag tgtgctacct
    23461 cttcaaaacc aagactatag gctatttcag agatgttcca gtcggtctgc ttcagcagta
    23521 ccttcgcctc ctgcaggata cggccgctga tcaggtctgt agtggttttg ccggtgttct
    23581 ccttcagcac cctgttcagg tgattcacat gcactgccag ccggtcggca taatcttttg
    23641 ccgtacgcag caacagccgc tgctgcgggg attctaccgg aaactgcctt tccagcagct
    23701 ctatgaacag cgatgatata cgtgccgcag cagtatgtgt aggatataat gccgtagcgg
    23761 gctgcagctt ctgcccgtaa tgtattacct ccatcacata gttgcggagc aggtcatatt
    23821 tataggcata atcagaagaa agctccttat acattttccg gaagatgaac aggatatctt
    23881 ccgcttcctc atcggtgagc tgaaacaccg gatagccacg gggctggaaa ataggcaggt
    23941 cgtccagtat aacgccgctc ttctgctgca ccaggaaatc ggctgtgaaa atacagaagt
    24001 agccggactg atgatcgtct tccggcaacc agtggtaagg aatcttcggc gtggcaaaca
    24061 gcagcgcatt cttctcaata tctatcacct tatctgcata ctccgccttg ttacggccgc
    24121 ttatcaggct gatcttataa taggcccgcc ggttgtagga catgggcaca cgcggcttgt
    24181 tggcggggaa cagatcatct atcctgaaaa cattgaagtg cccgatctcc ttgtttatac
    24241 cttccggaat caaggaggct gtttcctgat aaaacccttc gagtgagata ggttccatac
    24301 attttctcat ttgcaataat caaagatagg gaaagaaatc cggtagcaga tgagcagaat
    24361 atttatcttc gtcagctaaa gaaaagatat aaatcagaca gatgaaaaaa ctattttttt
    24421 cggtattgat aatagcttcc ataaaaacgc aggcacaaca ggacatgaag atgaaatcct
    24481 ttgtaggcgg acttatgagc agaatgacgc tggaagaaaa aatcggccag ctcaacctgg
    24541 tagtacccgg cggcggcaca gtaaccggcg ctgtagtaag tcaggatgtc gatgaaaaaa
    24601 ttcgtaaagg aaacgtaggc ggacttttcg gcgtcaccgg tccggaaagg ctccgcaaaa
    24661 ttcaggatat cgcggttaaa aatacccgtc tccatatccc gctgattttt ggcctcgatg
    24721 ttattcatgg ctacaggaca gtattcccta taccgctggg cctatccgct tcctgggata
    24781 tggcgctgat agaaaacagt gcacgtatcg ctgccaccga agccactgca gacggcatct
    24841 gctgggccta ctccccgatg gtagacatcg cacgcgatcc acgctgggga agaattgcag
    24901 aaggctccgg ggaagatccc tacctcggct cccggattgc cagtgctatg gtaaaaggct
    24961 accagggcag cgattacagc aagggcaaca ccctcatggc ctgtgttaaa cactttgcac
    25021 tgtacggcgc tgccgaaggc ggccgcgact acaactccgt ggacatgagc cgcattaaaa
    25081 tgtacgaata ttatctccca ccctataaag ccgctatcga cgcaggcgta ggcagtatca
    25141 tgacttcctt caacgatgtg gatgctgttc ctgccaccgg caacaaatgg ctgctcaccg
    25201 acctcctgcg caaacagtgg ggcttccggg gcctcgttgt cagcgattat accgctgtca
    25261 atgaaatgag cgcacatggt ctgggagatc tgcaggccgt atctgcccag gcactgcgtg
    25321 ccggcctgga tatggacatg gtaggcgaag gttttcttac cacactcaaa aaatcactg
//
