LOCUS       NZ_JAABOK010000001     20972 bp    DNA     linear   CON 29-MAR-2024
DEFINITION  Chitinophaga solisilvae strain O9 NODE_1, whole genome shotgun
            sequence.
ACCESSION   NZ_JAABOK010000001
VERSION     NZ_JAABOK010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Chitinophaga solisilvae
  ORGANISM  Chitinophaga solisilvae
            Bacteria; Bacteroidota; Chitinophagia; Chitinophagales;
            Chitinophagaceae; Chitinophaga.
REFERENCE   1  (bases 1 to 776765)
  AUTHORS   Jianli,Z. and Weiwei,P.
  TITLE     Chitinophaga flavus sp. nov., isolated from forest soil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 776765)
  AUTHORS   Jianli,Z. and Weiwei,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-JAN-2020) School of Life Science, Beijing Institute of
            Technology, 5 South Zhongguancun Street, Beijing 100081, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.5.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 246.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009928525.1-RS_2024_03_29
            Annotation Date                   :: 03/29/2024 05:41:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,090
            CDSs (total)                      :: 6,009
            Genes (coding)                    :: 6,004
            CDSs (with protein)               :: 6,004
            Genes (RNA)                       :: 81
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 16S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 0 of 5
            Pseudo Genes (incomplete)         :: 5 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:41:33
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 491095
            Orig. end                         :: 512067
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAABOK010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20972
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="3"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20972
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20972
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10972](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10972
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            993..1811
                     /locus_tag="GWG06_RS01720"
     CDS             993..1811
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (50-153). E-value:
                     8.4e-21. Score: 66.6. Matches aSDomain:
                     nrpspksdomains_GWG06_RS01720_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014217864.1"
                     /locus_tag="GWG06_RS01720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_160710964.1"
                     /sec_met_domain="PF00561 (E-value: 2.2e-17, bitscore: 58.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.5e-14, bitscore:
                     50.3, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLHRIILFLVCLLLQTFAAKAFQHTATDSATYFRSFDNTRIHYTS
                     KGNGEPVILVHGFITNGNSWLATPLYDSLLKHHFRVITLDLRGNGTSDHPHDSLAYLDD
                     AEAKDIMALATHLQLGAYRIVGYSRGAIIAARLLVLDKQRVRCGVLGGVGTGFTDPAWP
                     RRLQFYDALSGKDVPELAAMVKNVQAAGLDQRALALMQFGQPATTAAEFALVQQPVLVI
                     GGDKDEDNDTGGSLAALMPRGMHGTVAGNHTTTLRSPWFAEWITDFLEKH"
     aSDomain        1143..1451
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GWG06_RS01720_Abhydrolase_1.1"
                     /evalue="8.40E-21"
                     /label="GWG06_RS01720_Abhydrolase_1.1"
                     /locus_tag="GWG06_RS01720"
                     /protein_end="153"
                     /protein_start="50"
                     /score="66.6"
                     /tool="antismash"
                     /translation="PVILVHGFITNGNSWLATPLYDSLLKHHFRVITLDLRGNGTSDHP
                     HDSLAYLDDAEAKDIMALATHLQLGAYRIVGYSRGAIIAARLLVLDKQRVRCGVLGGV"
     CDS_motif       1350..1394
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GWG06_RS01720_0001"
                     /evalue="1.50E-03"
                     /label="NRPS-te1"
                     /locus_tag="GWG06_RS01720"
                     /protein_end="134"
                     /protein_start="119"
                     /score="11.2"
                     /tool="antismash"
                     /translation="GAYRIVGYSRGAIIA"
     gene            complement(1820..2263)
                     /locus_tag="GWG06_RS01725"
     CDS             complement(1820..2263)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012575.4"
                     /locus_tag="GWG06_RS01725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Rieske (2Fe-2S) protein"
                     /protein_id="WP_160710966.1"
                     /transl_table=11
                     /translation="MERRKFVSNVGLTLVLACTAGMAACSKGGGGYGSSPDPGPGGGSA
                     RVTLNLTSDLTQVGDFRIANGVIVIRTGTGNTAAAFSALSSTCTHQGCTVSTFSKASGL
                     IECNAPCGHGSRYTATGAVNTGPAAAALTPYSITVNGNMLTVS"
     gene            complement(2330..3163)
                     /locus_tag="GWG06_RS01730"
     CDS             complement(2330..3163)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012791301.1"
                     /locus_tag="GWG06_RS01730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helical backbone metal receptor"
                     /protein_id="WP_127044050.1"
                     /transl_table=11
                     /translation="MTSSRHWDGNSPRTFRDQLQRTVTLAKAPERIISLVPSQTELLYT
                     LGLEKEVAGITKFCVHPAAWFRSKTRVGGTKNVHADIVRSLQPDLIIANKEENTAADVE
                     ALMKDYPVWVSDIRTLEDALEMIAGVGAITCREAAANALISDIQTQFSALQPLTPPVPT
                     AYFIWRNPWMVAGGDTFIRQMMQRCGLQNVFADMPRYPAITPEQLAGSGCRLVLLSSEP
                     YPFKEKHIAELQEILPAARILLVDGEMFSWYGSRLAEAVPYFRQLLDIPAFHFSR"
     gene            complement(3135..4493)
                     /locus_tag="GWG06_RS01735"
     CDS             complement(3135..4493)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018629990.1"
                     /locus_tag="GWG06_RS01735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyridoxal-phosphate dependent enzyme"
                     /protein_id="WP_127044051.1"
                     /sec_met_domain="PALP (E-value: 3.4e-69, bitscore: 228.6,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYVNNILETIGHTPLVKLNRVTASLPCQVFAKVEFFNPGNSIKD
                     RMAIKMVEVAEQKGLLKPGGTIIEGTSGNTGMGLALAAVIKGYKCIFTTTDKQSKEKVD
                     ILKAVGAEVIVCPTNVEPEDPRSYYSVSKRLATEIPNSFYVNQYDNLANRDAHYEQTGP
                     EIWDQTDGKVTHLVVATGTGGTITGTGRFLKEKNPDIKVWAIDSYGSLLKKYYETGELD
                     MNEVYPYITEGIGEDFVPENYDMSVIDAFEKVTDKDGAVMARRITKEEGIFVGYSAGSA
                     IAGLLQLKASLKPEDVVVVVFHDHGSRYVGKVYNDQWMMERGFLDVKTVKDVVNARRNL
                     PLVTVTPDERVSDAIAKMKKFDIEHIPVKRDSEIVGSVSENGLFNKLIDDSNLKDALIG
                     QVMQAPFPLVSQDTPIEKLSVYINRENGAVLTKDDSGDHHIVTKYDIIQALGR"
     misc_feature    complement(4592..4605)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 21.42"
                     /tool="antismash"
     misc_feature    4593..4606
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 20.58"
                     /tool="antismash"
     misc_feature    4593..4608
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 23.54"
                     /tool="antismash"
     misc_feature    complement(4595..4608)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 20.52"
                     /tool="antismash"
     misc_feature    4596..4609
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 21.3"
                     /tool="antismash"
     misc_feature    complement(4596..4611)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 20.94"
                     /tool="antismash"
     gene            4784..5428
                     /gene="bioD"
                     /locus_tag="GWG06_RS01740"
     CDS             4784..5428
                     /EC_number="6.3.3.3"
                     /GO_function="GO:0004141 - dethiobiotin synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="bioD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012791303.1"
                     /locus_tag="GWG06_RS01740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dethiobiotin synthase"
                     /protein_id="WP_127043834.1"
                     /transl_table=11
                     /translation="MNRIFITGIGTGVGKTVTAACVTAALEADYWKPVQSGMEEGTDTA
                     TIQALLAGTTTICHPEAYVLKEPASPHLAARMEHITIDTSRITAQADGITGNRPLIIEG
                     AGGLLVPLNDEMSTLDLIRQLQARVIIVAQNYLGSINHSMLTAKVLQHTGVPVMGWIFT
                     GHHHSNEDDVIRWSGYPSLGRIPQAGEVNSAFVMEQARLLTGPLNASLYDH"
     gene            5418..5999
                     /locus_tag="GWG06_RS01745"
     CDS             5418..5999
                     /EC_number="6.3.3.2"
                     /GO_function="GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA]"
                     /GO_process="GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR02727.1"
                     /locus_tag="GWG06_RS01745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="WP_160710968.1"
                     /transl_table=11
                     /translation="MTTKKDIRKFFLEERLNLPDEQAQALNRRLLEQVQELDYTGVGTL
                     HLFLPISEKKEVDTWPLAAWLRERFPAIRLALSRADMKTGEMFHYAWEAHTALVKNKFG
                     IPEPAGGDELPATDIDLVFVPLLAFDREGQRVGYGKGMYDRFLKECRPDVRTVGLSLFE
                     PVEKITDTDAWDVPLHTVVTPAHIYHFKQF"
     gene            6002..7072
                     /gene="lpxK"
                     /locus_tag="GWG06_RS01750"
     CDS             6002..7072
                     /EC_number="2.7.1.130"
                     /GO_function="GO:0009029 - tetraacyldisaccharide 4'-kinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lpxK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012791305.1"
                     /locus_tag="GWG06_RS01750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tetraacyldisaccharide 4'-kinase"
                     /protein_id="WP_160710969.1"
                     /transl_table=11
                     /translation="MLKYLKILLYPFSLLYGLVMWIRNRFYDKGLLTAVEFDIPTIAAG
                     NLSVGGTGKTPHVEYLIRLLKDTFRVATLSRGYNRRTSGYILADEHSTAADIGDEPMQF
                     HEKFPEISVCVGEERMLAIPQLLGDEPGTQVVLLDDAFQHRSIKPGMNILITDYRRRFT
                     RDHVVPFGRLREGRKGYMRADCIIVSKCPPDLSVAEKQAIEKEISPLPHQRLFFTTLQY
                     GALYDMITRQPVEIPASATVLLACGIARPEPLLEALKNRFSQVFLLSFPDHYYYSEKDI
                     ANIGKELNDLPGKDKIVITTEKDAVRLHLLKKELAEQNLQLAVMPVEISFLFGEADSFN
                     NFIFDYVGRHLPVPGQ"
     gene            7088..9973
                     /gene="rnr"
                     /locus_tag="GWG06_RS01755"
     CDS             7088..9973
                     /EC_number="3.1.13.1"
                     /GO_function="GO:0008997 - ribonuclease R activity
                     [Evidence IEA]"
                     /GO_process="GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rnr"
                     /inference="COORDINATES: protein motif:HMM:TIGR02063.1"
                     /locus_tag="GWG06_RS01755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ribonuclease R"
                     /protein_id="WP_160710970.1"
                     /transl_table=11
                     /translation="MSKKKKDKKSPGQKKTFRGVVELTKSGMAFVIVPGLTKDIMVKQK
                     NLHTALDKDEVLVDVIKHARGEGRQEGIITDILKRNKTEFTGTLQISKSFGFLLTEKGM
                     FMPDIYIPANSLKDAKNGDKAVVKIVAWGEKSRKPVGEVIEILDASDTNDLAMKEILIE
                     AGFPLSFPDEVLEELAVIREEITETEVRKRKDVRNILTFTIDPVDAKDFDDAISFRLLK
                     NGLYEIGVHIADVSHYVIPGTELDKEADKRATSVYLPDRVLPMLPEKISNELCSLRPKE
                     DKLTFSAIFQMNEKGEVKHHWIGRTLIHSDHRFTYEDAQEIIEGNSNGPHKEEILLLNK
                     IAQQLRQERFKHGAINFSSQEVRFKLDENGKPIGIVIKESKEAHQLIEEFMLLANRTIA
                     AYVAKIRVNKQPVPFPYRVHDTPDEEKLKVFASFAGKFGYKFDTSSPENIARSFNKMLQ
                     LVQGKPEQHVLETLGIRTMAKAIYTTENVGHYGLGFEDYCHFTSPIRRYPDVLVHRVLA
                     ECLAGNIHPDKHMEKKCKHDSEMERKAMEAERAANKYKQVEYMQQYIGHTFEGVISGVA
                     HFGFWVETVDTKCEGLVSIHNLNRKEEFVFNEAEYALVGQASGRKFRIGEKVNIRVVAA
                     NLAKRQLDYDLESELGVAGRDSKPFAQPGRRDDQRRDDRRDRDRDHRRDDRGRKKKKGK
                     HGGNYIPQKQWQRDDKPAALPVTVQVPQEVAPDPVVDKVNAETHVVNETAAAIPAEKAP
                     VVTSPAKSSPAKSSSGKERVNSEKAGVKKAAEKKEVKEAPVKTAAAKKVKEKAAKVVKA
                     PEKEPEAVKEKVVKSAAGKAPATKKAVAEKETPVKKAVVKKAVPEKTAAAKTTQKKETA
                     AKTAKQETPKKTAPAKAAAKKATAEKATVKTAAPKKAAASKPSAVKATAPKKAAAKTAA
                     PKKAAAGKAVKAPAKKAATTKKAAAKGKKKE"
     gene            10001..10972
                     /locus_tag="GWG06_RS01760"
     CDS             10001..10972
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012791307.1"
                     /locus_tag="GWG06_RS01760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_160710971.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.9e-65, bitscore:
                     215.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHSFQELIEQFGQRFEHRQFPEQPSRLYDAASHILEIGGKRIRPV
                     LSLMGNELFDTLHDDAFHVGAAVELFHNFTLIHDDIMDKAPIRRGKPTVHMIYGDSAAI
                     LAGDVMLINVYEKLNKIRAHYKHKIIAGFNKAAIEVCEGQQLDMDYETMDPEQVRYDDY
                     VRMIGLKTSVLLAASLQLGAVIGGAGEGNQEHIYNFGKNIGIAFQIQDDYLDAFGDPEK
                     FGKQQGGDILVNKKTFLLLKALELCNPAQHNELKTLLASSPDDKVDRVLEIFKSCKADI
                     WAEKEKERFQEKAFESLESIAVLSSRKKPLMELANYLLNRQQ"
     misc_feature    11006..11022
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 21.29"
                     /tool="antismash"
     gene            11104..12735
                     /locus_tag="GWG06_RS01765"
     CDS             11104..12735
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012791309.1"
                     /locus_tag="GWG06_RS01765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amino acid permease"
                     /protein_id="WP_160710972.1"
                     /transl_table=11
                     /translation="MSNSLFRKKSLTSIIKDANDGLTDGLETGGMHKVLKVKDLTAMGI
                     AAVIGAGIFSTIGEASFHGGPGVSLLFLITAITCGFSALCYAEFASRVPVSGSAYTYSY
                     VTFGELAAWVIGWALILEYAIGNIAVAISWSGYCNNLLRGLGLSLPAWLSSNYDSASPE
                     TIAAAPHIGSLPVIVNLPAFIVVVLITYLAYVGIRESKRSANFMVGLKILVILFVIVLG
                     FFYVNKSNWVPFMPNGFSGVLKGVSAVFFAYIGFDAVSTTAEECANPQRDLPKGMIYSL
                     VICTVLYILISFVLTGMVPFYKLKVDDPLAFVFDEVHLPWISYLISVSAVIATTSVLLV
                     FQIGQPRIWMSMSRDGLLPKRFAKIHPRFKTPSFATIITGIIVGVPALFLNLTIVTDLT
                     SIGTLFAFILVCGGVLMLPPQEKGDGKRFRLPYINGQIVVPVLVTGLVIFFHKELLQKL
                     SFAGGWEVWKHNIPFFIFVVVTVLITYFSFARKLSLIPVLGLLSCFYLMTEIALKNWIV
                     FSIWLVIGLSIYFLYSYRHSKLKSAV"
     gene            12804..13271
                     /locus_tag="GWG06_RS01770"
     CDS             12804..13271
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012791310.1"
                     /locus_tag="GWG06_RS01770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DoxX family protein"
                     /protein_id="WP_127043840.1"
                     /transl_table=11
                     /translation="MNMLQRVEHWGDTHHPKWLSVVRILLGVFLMYIGVMFVQNRDALI
                     AVINDNPTLAALSVILAHYVVFAHTVGGLFIAMGLLTRFSALVNIPVLLGAVFFVHSAT
                     GLFNMYPMMGLSLLVLFLLIFFLIEGSGPISVDDYMRRHPEKRRNKQYADF"
     misc_feature    13341..13355
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.47"
                     /tool="antismash"
     misc_feature    complement(13342..13357)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.13"
                     /tool="antismash"
     gene            13419..14483
                     /locus_tag="GWG06_RS01775"
     CDS             13419..14483
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013844.4"
                     /locus_tag="GWG06_RS01775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Smr/MutS family protein"
                     /protein_id="WP_127043841.1"
                     /transl_table=11
                     /translation="MKYQTGDRILLLSSKEEGTVVDIINDNMVMIEVKGTSFPVYLDQI
                     DFPYFHRFTQQKLVKEKPRQIPGDEIKVDRKKYEVFKTDKGMFMSVLPVYQMDGYDETV
                     KLMKFHLFNDTPHAMRFYFQIWLNNQMDLEIKNEIQPYNHFYLADLIFESLNDNPRFEF
                     TFFLKEPQPKLAPSVKKTWKIKPKQMFMQLQELRSKEEATLTYPLFEKYPEKEAEPTPP
                     PASASAPAGKKAAPIKTVGSGNFASLLSKIQLQPETSLEPKHEVDLHIEVLEKNWKGLS
                     NIAILAIQLNAFQRYLELAISHHQHSMIVIHGVGKGKLRDEIHNILKQTPEVNTFVNQY
                     HGKYGYGATEITFK"
     ncRNA           14612..14982
                     /db_xref="RFAM:RF00010"
                     /gene="rnpB"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="GWG06_RS01780"
                     /ncRNA_class="RNase_P_RNA"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /product="RNase P RNA component class A"
     gene            14612..14982
                     /gene="rnpB"
                     /locus_tag="GWG06_RS01780"
     gene            15052..15465
                     /locus_tag="GWG06_RS01785"
     CDS             15052..15465
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021221.4"
                     /locus_tag="GWG06_RS01785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4870 domain-containing protein"
                     /protein_id="WP_160710973.1"
                     /transl_table=11
                     /translation="MDQKEERNWGTYVHLGGILGTIIIPTVGNIVLVLVLWLIKRNESK
                     FVDEQGKEAINFQITISLVGAALSIIGNITSGLWSLSHIFWHSRGDYFDFSWGWHSLHP
                     ILWVINIIFSIIAAVKANEGISYKYPFNLRLVK"
     gene            complement(15590..17275)
                     /locus_tag="GWG06_RS01790"
     CDS             complement(15590..17275)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012311.4"
                     /locus_tag="GWG06_RS01790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="S8 family serine peptidase"
                     /protein_id="WP_202182922.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 8.5e-53, bitscore:
                     174.6, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLFSREVAVLAGCVAMMTAFTTRTAAQGKTLPKNWHLLSYDTDS
                     VYGTGIEKAYKELLKGKKSTPVIVAVIDSGIDTLHEDLKGILWTNPREIPGNGKDDDGN
                     GYIDDIHGWNFLGGKDGGSVKEDSDEASREYYRFKNKYGNPDSALDKNSAEYATWQRIV
                     AKVDKPSNESMMQYKSMVKLQENVNKCETILKNYLHTDDFTVGKLDSIQTTSQDVLLAR
                     NFMTRLLKSAGEESPAFNEFKNEFDAYMSDLKRKTEGAETPPNENRQKIVGDNYDDIKD
                     NKYGNNDVMGAFGFHGTHVSGIIAAARNNGVGMDGVADNVRIMAVKAVPDGDERDKDVA
                     LAIRYAVDNGAQIINMSFGKPFSPHKEWVDDAIRYAEKKGVLIVHAAGNDGNNNDSVPN
                     FPNTDFLDGTHPTNYITVGASSSGLGPDKVAGFSNYGKKHVDIFAPGVQIYSTIPGGNK
                     YGSASGTSMAAPVVAGVAALVLSRYPDLSARQLKYILERSATPLADGTTEVNKPGSDEK
                     IKFADLSVTGGLVNAYEALKLAASIKGENVKKPQKAKMKPVKKN"
     misc_feature    complement(17674..17688)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 20.46"
                     /tool="antismash"
     misc_feature    17871..17880
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 17.48"
                     /tool="antismash"
     misc_feature    17891..17906
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 21.43"
                     /tool="antismash"
     gene            complement(18129..19658)
                     /locus_tag="GWG06_RS01795"
     CDS             complement(18129..19658)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012791316.1"
                     /locus_tag="GWG06_RS01795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_127044278.1"
                     /sec_met_domain="Aldedh (E-value: 1.6e-136, bitscore:
                     450.6, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEDILQAFGIGAQQSGVSTGKHWLSAGGADIVSFSPVDNKKIAT
                     VKSATREDYDNVIAVAHQAFAAWRQWPAPRRGEVVRQIGDALRQHKEHLGRLVSYEMGK
                     SLQEGYGEVQEMIDICDFAVGLSRQLYGLTMHSERPGHRMYEQWHPIGITGIISAFNFP
                     VAVWSWNSMLSWVCGNVCVWKPSEKTPVTALACQRIVETVFAANNVPEGVSCLVTGGRE
                     VGEWMAGDHRVPLVSATGSTRMGKSVAAAVGARLGRSLLELGGNNAIIVSQDADLDMSL
                     IGAVFGAVGTAGQRCTTTRRLIIHESVYDAFTARLVKAYGQLRIGNPLNENNHVGPLID
                     TDAVKAYLHTIEQVKQQGGTFLVEGGVLEGAGFESGCYVKPCIAAVENTYDIVQHETFA
                     PILYVMKYQTLTEAIAMQNDVPQGLSSAIMTLNLREAEQFLSHAGSDCGIANVNIGTSG
                     AEIGGAFGGEKETGGGRESGSDSWKAYMRRQTNTINYSDKLPLAQGIKFDL"
     gene            complement(19683..20573)
                     /locus_tag="GWG06_RS01800"
     CDS             complement(19683..20573)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012791317.1"
                     /locus_tag="GWG06_RS01800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF1338 domain-containing protein"
                     /protein_id="WP_127044277.1"
                     /transl_table=11
                     /translation="MLKEVLNGLMSRYQERVPDVAAVIAAMVRDGLISQADDIENDHIA
                     FRTMGVPQLGVQSLEKIFLHYGYTKMDHYYFAGKKLDAWWYAPPEPKYPRIFISELRVN
                     DLSPEAQAIIRSYTDEVTVDPVTRLNLDDSQAVDTFLHSGLWRTPTLADFKALSAESEY
                     AAWVIYNRYYLNHFTVSVHNLPPGYNTVAEFNAFLEKNGFILNDAGGKIKTSPDGRLLQ
                     SATVARMIEATFAGGDTVKIAGSYVEFAERKVLPEFAHLPAAEIKRQHRREGFEAGNAD
                     KIFESTYATQTKKSS"
ORIGIN
        1 tcggtatcaa tattcatttt gataacgccg taacccagtg cttctgcgat ctggtgcttc
       61 ggagagccgc tgccgccgtg gaatacgtag tataccggct tggctttggt gccgaatttc
      121 tgctggatat attcctggct gttctgcagg atcaccggac gcagttctac gttacccggg
      181 ctgtatacgc catgtacgtt tccgaaagcg gcggctacag tgaagcggct gcctacttta
      241 gacagtactt cataagcgta ggccacatct tcaggctggg tatataactt ggagttatct
      301 acgccggagt tgtccacacc gtcttcttct ccaccggtta cgcccagctc aatttcgatg
      361 gacataccca gtttattcat tctttcaaaa tatttatggg agatttcgat gttctcctgg
      421 ataggctctt cagacagatc cagcatgtga gagctgtaca aaggctggcc atgcagtttg
      481 aaatattctt caccggcagt cagcagaccg tcgatccatg gcaaccattt tttagcggcg
      541 tggtcagtat gcaatacaac aggaacgcca tagtacttag ctacttcatg cacgtgttta
      601 gcaccggaga taccgccggc gatgtttgcc tgcagcttat cgttaggcat gcctttaccg
      661 gcataaaact gcgcaccccc attggaaaac tgtataatta ccggtgaatt tactttcgca
      721 gctgtttcca gcaccgcatt cacggagttg gttcccacaa cattcacggc aggcatagca
      781 aatccgttgt ctttggcatc gttatacagc gcatccagct cttcgccgaa taatacgcca
      841 gctctgtatt ttcccatact ctaaaaatgt atttgttttt taaggaaagc aaatataagc
      901 aggaaaaaat aagatttata gcgaaatgta tttattgcag cgataaaagt aaagagataa
      961 aaatgtattt tacccggata tcctccatta tcatgttaca tagaattatt cttttccttg
     1021 tttgtctgtt actgcaaacc tttgctgcta aggcctttca gcatactgca accgattccg
     1081 ccacttactt ccgctccttc gataatacgc gtattcatta caccagtaaa ggaaacggag
     1141 agccggttat ccttgtgcat ggcttcataa caaacggtaa ttcctggctg gcaacgccgc
     1201 tgtacgattc gctgctgaaa catcatttcc gggtgattac gctggacctg cgcggcaacg
     1261 gcacttccga ccatccgcac gacagcctgg cctatctgga tgatgcagaa gcaaaagata
     1321 ttatggcgct tgccacgcat ctgcagctgg gcgcctacag gatagtaggg tattcccgcg
     1381 gagccattat cgcagcccgg ctgctggtgc tggacaaaca acgtgtgcgc tgcggcgtgc
     1441 tgggaggcgt aggcaccggg tttactgatc cggcatggcc ccgccgcctg cagttctatg
     1501 atgccctctc cgggaaagat gtcccagagc tggcggccat ggtgaaaaac gtacaggcgg
     1561 cagggttaga ccagcgcgcg ctggcgctga tgcagttcgg gcagcccgct accaccgccg
     1621 cggaatttgc actggtacaa cagccggtac tggttatcgg aggcgataaa gacgaagaca
     1681 atgatacagg cggttccctc gcagccctta tgccgcgcgg tatgcacggc actgtagccg
     1741 gcaatcatac tactacattg cgctctccct ggtttgcgga gtggatcaca gattttttag
     1801 aaaaacattg acagggatct taactaactg tcagcatatt accatttacc gtaatgctgt
     1861 agggagtgag cgccgcagca gccggtccgg tgtttacagc gccggtggct gtatacctgc
     1921 tgccatggcc gcatggcgcg ttgcattcta tgaggccgga agctttgctg aaagtagaaa
     1981 cggtacatcc ctgatgggtg caggtacttg ataaagcgct gaaagccgcg gcggtattgc
     2041 ctgtgccggt acggataaca atcacgccat tggcaatcct gaaatcgcct acttgggtaa
     2101 ggtcgctggt aagattcagg gtaaccctgg cggatccgcc accagggccg ggatcaggag
     2161 atgatccata accgccgcct cctttgctgc aggcagccat tccggcggta caggccaata
     2221 ccagcgttag ccctacgttt gatacaaatt tccttctttc cataaagtaa attttacggt
     2281 gacagtacaa cgtgtatgac ttgtacgcgg aagaaaggga acaggttgcc tagcggctga
     2341 aatgaaaggc gggtatgtcc agcagctgcc ggaaataggg aaccgcttcg gccaggcggc
     2401 tgccgtacca ggagaacatt tctccgtcta ccagcaaaat acgcgctgcc ggcaggatct
     2461 cctgcaattc ggcgatatgt ttttccttaa agggataagg ttcggaagaa agcagtacca
     2521 gccggcagcc actgccggcc agctgttccg gtgtgatggc agggtagcgg ggcatatctg
     2581 caaatacatt ctgcagtccg cagcgctgca tcatctgccg gatgaatgtg tcgccaccag
     2641 ccaccatcca tggattgcgc cagatgaagt aggcggtggg aacagggggc gttaaaggct
     2701 gaagtgcgga aaactgtgtt tgtatgtcgc tgataagcgc gttagcagca gcttcccggc
     2761 aggtgatggc gccaacgccg gcaatcatct ccagcgcatc ttccagcgtc cggatgtcgc
     2821 tcacccatac cggataatct ttcatcagcg cctctacatc agcggccgta ttttcttctt
     2881 tattggcgat gataaggtct ggctgcaggg aacggacaat atcggcatgc acgtttttag
     2941 taccgcctac acgggttttg ctacggaacc acgctgccgg atgtacgcag aatttagtga
     3001 tgcctgccac ttctttttcc agccccagcg tatataataa ttccgtttgc gaaggcacca
     3061 gagagatgat cctctccggc gccttcgcca gtgttaccgt gcgttgcagc tgatcgcgaa
     3121 acgtgcgggg gctgttaccg tcccagtgcc tggatgatgt catacttagt tacgatgtga
     3181 tgatctccgc tgtcgtcttt agtgagtaca gcaccgtttt cccggttgat atagacagac
     3241 agtttttcta tcggcgtatc ctgacttacg agcgggaatg gcgcctgcat gacctgcccg
     3301 atgagtgcat ctttcaggtt gctgtcatca atcagtttat tgaacaggcc gttttcagaa
     3361 acggaaccaa caatttcgct gtcacgttta acggggatat gttcaatatc gaattttttc
     3421 attttcgcaa tggcatcgct gactctttca tctggtgtaa ccgttaccag tggcagatta
     3481 cggcgcgcgt tcaccacgtc tttcaccgtt ttgacgtcca gaaatccgcg ttccatcatc
     3541 cattggtcgt tgtatacttt tcctacataa cggctgccat gatcgtggaa aaccactact
     3601 accacatctt ccggtttcag ggaggctttc agctgtaaaa gacctgctat ggcggaaccg
     3661 gcagagtaac ccacgaagat gccttcttct ttcgtaatac ggcgggccat aacggcgccg
     3721 tctttatcag ttactttttc gaaggcgtct atcacgctca tatcgtagtt ctccggcaca
     3781 aagtcttctc ctataccttc agtgatatag ggatatactt cgttcatatc cagttcgccg
     3841 gtttcataat attttttcag gagagagccg tagctgtcaa tagcccatac cttgatatcc
     3901 ggatttttct ctttcaggaa cctgcctgta ccggtgatgg taccaccggt gccggtagct
     3961 actaccaggt gggtcacttt accatccgtc tgatcccaga tttccggacc ggtctgctca
     4021 tagtgcgcat cgcggttggc gaggttatcg tactggttta catagaagga gttgggtatt
     4081 tccgtagcca gccttttgga tacggagtag taggagcggg gatcttccgg ttccacgttg
     4141 gtcggacaca cgattacttc cgcgcctacg gctttcagga tatctacttt ttccttggat
     4201 tgtttatcgg tggtggtaaa aatacatttg tagcctttga tgacggctgc aagtgccagg
     4261 cccataccgg tattgccgga ggtgccttca atgatggtgc cgccgggttt gagcaggcct
     4321 ttctgttcgg caacttctac cattttgata gccatcctgt ccttgatgga gttgcccggg
     4381 ttaaagaatt ctaccttggc aaacacttgg cagggcaggg aagccgttac gcggttcagt
     4441 tttaccagtg gggtgtggcc aatcgtttcg agtatgttat taacgtattt catataaaat
     4501 aatgaggttg tgcggttgta aattacgaat tcagaatcag gaatcgtgca tttatcgcag
     4561 attctcccat ctggcataga aaagaacggc tttatgataa ttattattta tttttttctt
     4621 ctgaaagatt tccctcactg aatttccttt aacgaaccga tacaaaaaat agaaaacaac
     4681 aatcccctca tcattcatca tgtatacccc cctctccgct gcatttataa ttcgtcctgc
     4741 ataattcgtc attcgtaatt cccaattcct atctttgccg gagatgaatc gaatatttat
     4801 aaccggtatt ggtaccgggg ttggaaaaac ggttactgcc gcctgtgtaa cagcagcact
     4861 ggaagcagat tactggaaac ctgtacagag cggcatggaa gagggcacgg atacggcaac
     4921 cattcaggcc ctgctggctg gtaccaccac catatgccac ccggaagcct acgtattgaa
     4981 agaacctgct tcgccgcacc tggcggcccg gatggagcat attaccattg atacttcccg
     5041 tattacagca caggcagacg gtatcacggg caaccggccg ctgattatag aaggcgccgg
     5101 cggactactg gtgccgctga atgacgaaat gtccacactg gacctgatcc ggcagctgca
     5161 ggccagggta atcattgtgg cgcagaacta cctgggcagc atcaaccatt ccatgcttac
     5221 cgcaaaagtg ctgcagcata caggcgttcc cgttatgggc tggatattta caggccatca
     5281 tcacagtaat gaagatgatg taatccgctg gagcgggtat ccttcactgg gccgcatacc
     5341 gcaggccgga gaggtgaaca gcgcctttgt catggaacag gcacggcttt tgacaggtcc
     5401 tctcaacgct tcactgtatg accactaaga aggatatacg aaaatttttc ctggaagaaa
     5461 gactgaacct ccctgatgaa caggcgcagg cgctgaaccg gcggctgctg gaacaggtgc
     5521 aggaactgga ttatactggg gtgggcaccc ttcatctttt tctgcctatt tcagagaaga
     5581 aggaagtgga tacctggccc ctcgctgcct ggctgcggga acgcttcccg gctatacgcc
     5641 tggcactttc ccgcgccgat atgaaaaccg gagagatgtt tcattatgcc tgggaggccc
     5701 ataccgcact ggtaaaaaat aaatttggta tcccggagcc ggcaggcgga gacgaactgc
     5761 ccgccacgga tatagatctt gtattcgtac ctttactggc ttttgaccgc gaaggacaac
     5821 gggtcggcta cggtaaggga atgtacgacc gcttcctgaa agaatgccgc ccggatgtac
     5881 gtacagtagg gctttccctg tttgaaccgg tagagaagat taccgataca gacgcctggg
     5941 atgtaccgtt gcataccgtc gtaacaccag cgcatattta tcattttaaa caattttagc
     6001 agtgctgaaa tacctgaaaa tactattata tcctttttcc ctgttgtatg gcctcgtgat
     6061 gtggatacgc aaccggttct atgataaagg cctgctcact gccgtagaat tcgatatccc
     6121 tactatcgcc gcaggcaacc tttccgttgg cggcaccggt aaaaccccgc atgtggaata
     6181 cctgatccgc ctgctgaaag atactttccg ggtggctacc ctcagccgtg gctacaaccg
     6241 tcgtacaagc ggttatatac tggctgatga acacagcacc gcagctgata tcggcgatga
     6301 gcccatgcag tttcatgaaa aatttccaga gatcagcgtt tgtgtaggag aggaacgcat
     6361 gctggccatc ccgcagctcc tgggcgatga gccgggcaca caggtagtgc tgctggacga
     6421 tgccttccag caccgatcta tcaaaccggg catgaatatc ctgattacgg attacagacg
     6481 ccgcttcacc cgcgatcatg tggtgccctt cggccgcctc cgcgaaggtc gtaaaggtta
     6541 tatgcgcgct gattgtatca ttgtttccaa atgtccgccc gacctgagcg tggcagaaaa
     6601 acaggcgatc gaaaaagaaa tcagtccttt gccgcatcag cggttgtttt ttactacctt
     6661 gcaatacggg gccctgtatg atatgattac acgccagccg gtggaaatac cggcatccgc
     6721 caccgtactg ctggcctgcg gtatcgccag gcccgaacca ttgctcgaag cgttgaaaaa
     6781 ccggttctca caggtattcc tgctttcctt ccctgatcat tactattact cagagaaaga
     6841 tattgccaat atcgggaaag aactgaacga cctgccagga aaggataaga ttgtcatcac
     6901 cacagagaaa gacgcggtga gattacacct gctgaagaaa gaactggcag aacaaaacct
     6961 gcaattagct gttatgccag tggaaatttc cttcctcttc ggagaagcag attcatttaa
     7021 taactttatt tttgactacg taggcaggca tctgccggta cccggtcaat aatacttact
     7081 acaagacatg agtaaaaaaa agaaagataa aaaaagcccc ggacagaaga agaccttcag
     7141 aggggtagtg gagttgacaa agtcaggaat ggcttttgtg attgtacccg gacttaccaa
     7201 agacatcatg gtaaagcaga agaacctgca taccgcactc gataaagatg aagtgctggt
     7261 ggatgtcatc aagcatgccc gcggcgaagg ccgccaggaa ggtatcataa cggatatcct
     7321 taaacgaaat aaaacggaat ttaccggcac cctgcagatc agtaagagct tcggcttcct
     7381 gctcacggag aaggggatgt ttatgccgga tatctatatt cccgccaatt ccctgaaaga
     7441 cgctaagaac ggagataagg ccgttgtaaa aattgtggcc tggggcgaaa aatcgcgcaa
     7501 acccgtaggc gaagtgattg agatcctgga tgccagcgat accaacgacc tggccatgaa
     7561 ggaaattctc attgaagccg gattcccgct cagcttcccc gacgaagtgc tggaagaact
     7621 ggccgttatc agggaggaaa taacggaaac ggaagtacga aaacgtaagg acgtacgcaa
     7681 tatcctgacc ttcaccatcg accccgttga tgccaaggat tttgatgatg ccatctcctt
     7741 ccgcctgctg aaaaacgggc tgtatgaaat tggcgtccac atcgcggatg taagtcatta
     7801 tgtgattccc ggaacagagc tggacaagga agcagacaaa cgcgctacct ccgtgtatct
     7861 gccggaccgc gtactgccca tgctgccgga aaaaatttcc aacgaactgt gctcgctgcg
     7921 cccgaaagaa gataaactga ccttctccgc catctttcag atgaacgaaa aaggagaagt
     7981 aaaacaccac tggataggcc gtaccctgat ccactcggat caccgcttca cctatgaaga
     8041 tgcacaggaa attatagaag gtaacagcaa tggtccgcat aaagaagaga tactactgct
     8101 gaataagata gcccaacaac tgcgccagga gcgctttaag catggcgcta tcaacttctc
     8161 ctcccaggaa gtgcggttca aactggatga aaacggtaaa cctatcggta tcgttatcaa
     8221 ggaaagcaag gaggcgcatc agctgattga agaattcatg ctgctggcca accggaccat
     8281 cgccgcctat gtggcaaaga tccgggtaaa caaacaaccc gtgccattcc cttaccgggt
     8341 gcacgatacg ccggacgaag aaaaactgaa ggtattcgct tccttcgccg gaaaattcgg
     8401 gtataagttt gataccagct ccccggaaaa cattgcccgc tccttcaata aaatgctgca
     8461 gctggtacag ggcaagcctg aacagcatgt gctggaaacc ctgggtatcc gtaccatggc
     8521 caaagcgatc tataccaccg agaatgtagg gcactacggt cttggctttg aagattactg
     8581 ccactttact tcccctatac gccgttaccc ggatgtactc gtacatcgtg tgctggcgga
     8641 gtgcctggcc ggtaatatcc atccggacaa gcacatggag aaaaaatgca agcacgattc
     8701 cgaaatggaa cgtaaggcca tggaagcgga aagggcagcc aacaaatata aacaggtgga
     8761 atacatgcag cagtacatcg gacacacttt tgaaggtgtt atcagcggtg tggcgcattt
     8821 cggcttctgg gtggaaaccg tggataccaa atgcgaaggg ctggtgagta ttcataacct
     8881 caaccggaag gaagaatttg ttttcaatga agcagaatac gcgctggtag gacaagccag
     8941 tggccgtaag ttccgcatcg gcgaaaaagt gaatatacgt gtggtggccg ccaacctggc
     9001 caaacgccag ctggattacg acctggaaag tgaactgggc gttgcaggcc gcgacagtaa
     9061 accgtttgcg cagcctggcc gcagggatga ccagcgccgt gacgaccggc gtgaccgcga
     9121 ccgcgatcat agaagagatg accgtggccg taagaagaaa aaaggaaaac acggaggtaa
     9181 ctacattccg cagaaacaat ggcaacgtga tgataaacct gctgcactgc cggtaactgt
     9241 tcaggtgccg caggaagtag cgcctgatcc ggtagtggat aaggtaaatg cagaaacaca
     9301 tgtagtgaat gaaactgcag ccgctatccc ggctgaaaaa gcgccggtag taacctctcc
     9361 ggcaaaatca tctccggcaa aatcatcttc cggaaaagaa agagtgaaca gcgaaaaagc
     9421 aggcgtaaag aaagctgcag agaaaaaaga agtaaaagaa gcgcctgtaa aaactgctgc
     9481 tgcaaagaaa gtaaaagaga aggcagcaaa agttgtaaaa gcacctgaaa aggaaccgga
     9541 agcggtaaag gagaaagtgg tgaagagtgc cgccggtaaa gcacctgcaa cgaagaaagc
     9601 ggttgctgaa aaggaaacgc cggtaaaaaa ggcagttgtt aaaaaagctg ttccggaaaa
     9661 gactgctgct gcgaaaacaa cacagaaaaa ggaaacagcc gcaaaaacag cgaaacagga
     9721 aacgcctaag aaaaccgctc ctgccaaagc agcagctaaa aaagccaccg cagaaaaggc
     9781 aacagtaaaa acagccgctc cgaaaaaagc agctgcatct aagccgtccg ctgtaaaggc
     9841 aacagcgcct aaaaaggccg ctgccaaaac cgccgcacct aaaaaggctg ctgccggaaa
     9901 agcagtgaaa gcaccggcaa aaaaggctgc cactactaag aaagctgctg ccaaagggaa
     9961 gaaaaaagag taaaaaaata taaaccaccg tctatttcag atgcattcat ttcaagagtt
    10021 aatagaacag tttggccaac ggtttgaaca caggcagttt ccggagcaac ccagcagatt
    10081 gtatgatgcg gcatcgcaca tactggaaat aggaggaaaa cgtatacgcc cggtattgag
    10141 tctgatgggt aatgaattgt ttgataccct gcatgacgat gcttttcatg taggcgcagc
    10201 cgtagagctt ttccataact ttaccctgat ccatgacgat attatggaca aagcgcctat
    10261 ccgccgggga aaacctacgg tgcatatgat ctatggtgat tctgctgcta tcctggccgg
    10321 cgatgtgatg ctgatcaatg tatatgaaaa gctgaacaag atacgcgcgc attacaagca
    10381 taaaatcatt gccggattca ataaggcggc catcgaagta tgcgaaggtc agcagctgga
    10441 tatggattac gaaacgatgg atccggagca ggtacggtac gacgactacg tgcgcatgat
    10501 tggcctgaaa acgtccgtac tgctggcggc gagcctgcag ctgggcgctg tcatcggcgg
    10561 cgcgggcgaa ggtaaccagg aacatatcta caacttcggt aaaaatatcg ggatcgcctt
    10621 tcagatccag gacgactatc tcgatgcctt cggcgatccg gagaaattcg gcaagcaaca
    10681 gggcggagat attctcgtga ataaaaaaac cttcctgctg ctgaaagcac tggagttatg
    10741 caacccggca cagcacaacg agctgaaaac cctgctggca tcttcccctg acgataaggt
    10801 agacagggta ctggagatct tcaaaagctg caaagcagac atatgggcag aaaaagaaaa
    10861 ggaacgtttc caggaaaaag catttgaaag cctggaaagc atcgcggtat tatcttcccg
    10921 caaaaaaccg ctgatggaac tggcgaatta cctgttaaac cgccagcaat aatttttata
    10981 ttcaaaatcg ccttatattc gcgaatgccg taaaaacggg cggactgtgt tcaacgcagc
    11041 ccgcctgctt ttaacggagt atttatttat tttactgact accttaaacg taattcctcg
    11101 ccaatgtcta attcgctgtt tcggaagaag tcccttacct caataatcaa agatgccaat
    11161 gacgggttga ctgatggcct tgaaacaggc ggtatgcata aggtgctgaa ggtgaaagac
    11221 cttaccgcaa tgggaattgc ggcggtaatc ggagccggta tattttccac tatcggggaa
    11281 gcctctttcc atggcggtcc cggtgtttcc ctgttatttc tgatcactgc cataacctgt
    11341 ggcttttctg cattgtgtta tgcagaattc gcctccaggg tacctgtatc cggcagtgcc
    11401 tacacctatt cttacgttac tttcggagag ctggccgcct gggtgatagg ctgggcgctg
    11461 atcctggagt atgccatcgg gaatatagct gtggctattt cctggagcgg ctattgcaat
    11521 aacctgctga gaggactggg gctgtcgctc ccggcctggc tgtccagcaa ctatgacagc
    11581 gcatctcctg aaacaatcgc tgctgcgccg catattggca gtttgcctgt tattgtgaac
    11641 ctgccggcct ttatagtggt ggtactgatt acctacctgg cttacgtagg catccgcgaa
    11701 agtaagcgca gcgccaattt catggtagga ctgaaaatac tcgtgatcct ttttgtgatt
    11761 gtacttggct ttttctatgt aaataaatcc aactgggtac cctttatgcc gaacggtttc
    11821 tccggtgtgc tgaaaggagt gtctgccgta ttttttgcgt atataggctt tgatgcggtg
    11881 agtactaccg cggaagagtg cgccaatccg caacgggacc tgcccaaggg aatgatctat
    11941 tcgctggtta tctgtaccgt attatatatc ctcatttcct ttgtactgac ggggatggta
    12001 ccgttttaca aattaaaggt agatgatccg ctggcttttg tttttgatga agtacacctg
    12061 ccctggatca gttatcttat ttctgtcagc gccgtaattg ccaccaccag cgtattgctc
    12121 gtattccaga tcgggcagcc ccgtatctgg atgagtatga gccgtgacgg cctgctgcca
    12181 aagcgttttg cgaaaattca tccgcgcttt aaaacgccgt cttttgccac tatcatcacc
    12241 ggtatcatcg taggggtgcc ggcgttattc ctgaacctca ccatcgtaac agacctgacc
    12301 agtataggca cccttttcgc gttcatcctg gtatgcggcg gagttcttat gttgcctccg
    12361 caggaaaagg gcgatggtaa acgcttccgg ctgccatata tcaatgggca gatcgttgtt
    12421 cctgtgctgg taacaggcct ggtcatcttt ttccataaag aactgctgca gaaattatcc
    12481 tttgccggtg gctgggaggt atggaaacac aatattccgt tctttatttt tgtggtggta
    12541 accgttctga tcacttattt ctcctttgcc cgcaaactct ctctgatacc ggtattgggc
    12601 ctgctcagct gcttttatct tatgacagaa atagcgctga aaaactggat agtattctct
    12661 atctggctgg taatagggct gagtatttat ttcctctaca gctatcgcca cagcaagctc
    12721 aaaagcgccg tctgaagcgg cgctatgcgt tcctgagtca tttatttttc gtaccttgac
    12781 agtagttctt taaatctttt tttatgaaca tgctacaaag ggtagaacac tggggtgata
    12841 cacatcatcc caaatggctg agtgtcgtac gcattctgct gggagtattc ctgatgtaca
    12901 taggtgttat gtttgtacaa aacagggatg cactcattgc ggttatcaat gacaatccga
    12961 cactggcagc attatccgtc atcctggcgc actatgtggt atttgcacat acggtaggag
    13021 ggctgtttat tgccatggga ttgctgacaa gattctccgc gctggtaaac attccggtgc
    13081 tgctgggcgc cgtgtttttt gttcattccg ccaccgggtt gttcaacatg tatccgatga
    13141 tgggcttatc cctgctggta ttattcctgc tgatcttctt cctgatagaa ggcagcggcc
    13201 cgatatcagt ggatgattat atgcgccgcc atccggaaaa gcgccgtaac aagcaatacg
    13261 cggactttta atccgttcat ccgcaccaga gcctgtgatt ttcaccattc acctgatggc
    13321 gcaggggagg tatatctccc ggaaaatcat tttccttcta atatctcccg ctaaaatccc
    13381 cgccaaaact ctatttttgc aattcagaag aatgcattat gaaataccaa acaggcgaca
    13441 ggatattact gttaagttca aaggaagaag gcactgtagt tgatatcatc aatgataata
    13501 tggtcatgat agaagtgaaa ggaacatctt ttccggtata tcttgaccag atagactttc
    13561 cgtattttca tcgttttaca cagcaaaagc tggtaaagga gaagccgcgt cagatacccg
    13621 gcgatgaaat aaaagtagac agaaaaaaat acgaagtttt taagacagac aaaggcatgt
    13681 tcatgtctgt actgcccgta taccagatgg atggctacga tgaaaccgtg aagctgatga
    13741 agtttcatct gtttaatgat acaccgcatg ccatgcgttt ctattttcag atctggctga
    13801 ataaccagat ggatctggaa atcaaaaacg agatacagcc gtacaatcat ttttatctcg
    13861 cagacctgat attcgaatcg ctgaatgata atccgcgttt tgagttcacc ttcttcctga
    13921 aagagccgca acccaagctg gctccctctg taaagaaaac ctggaagatc aagcccaaac
    13981 agatgttcat gcagctgcag gaattacgca gcaaggaaga ggcgaccctc acttatccgt
    14041 tatttgagaa gtacccggaa aaggaagcag aaccaacacc accgccggca tcagcatctg
    14101 ctcctgccgg aaagaaagcc gcgccgatca agacggtagg ctccggaaac ttcgccagtc
    14161 tgttaagtaa aatacagctg cagccggaaa cctcgctgga acccaaacat gaagtagacc
    14221 tgcacattga agtgctggaa aaaaactgga aaggcctcag caatattgcc atcctggcta
    14281 tccagctcaa cgctttccag cgttaccttg aactggctat ttcccaccac cagcacagca
    14341 tgatcgttat tcacggcgtt ggcaaaggca aactccgcga cgaaatccac aacatcctga
    14401 aacaaactcc ggaggtaaat acttttgtaa atcaatacca cgggaagtat gggtatggtg
    14461 caaccgaaat aacttttaag tagttatttg attatttgag atttagttat ttaaaatgca
    14521 gcaaagattt acgtgtaaaa tcttcgctgc attttaaata actaaatctc aaataatcaa
    14581 ataagtaaat atccattatc tttgcgctcc aactacaaac cgtgctatcg tctctcagtt
    14641 ttatggggga aggaaagtcc ggacagcaca gagcaacaca ccacctaacg ggtggggccc
    14701 ggcttgccgg gtacagcgag tgccacagaa aataaccgcc tcactgcaaa gcggggtaag
    14761 ggtgaaaatg tggggtaaga gcccacggta taggcaggta actgtttgtg cgggtaaacc
    14821 ttgtgtgctg aaatgccatg tatacggtcg tttgagggct gctcgcccga tgaccgaggg
    14881 taggcagata cagttgacgt gtgagcgtca tcgcagataa atgatagcaa tccccggctt
    14941 cggcagggga gacagaatcc ggcttacagg tttgtagttt tttctttttt tccactccgc
    15001 tttgttatta caaaataagc cgttaacttt tccatataaa tcaatttata tatggatcag
    15061 aaagaagaac gtaactgggg aacctatgtg catctcggag gcatactcgg tacgatcatt
    15121 atccccaccg tcggcaatat cgtcctggta ttggtattat ggctcatcaa gcgtaacgaa
    15181 tcaaagttcg tggatgagca gggtaaggaa gccatcaatt tccagattac catcagtctg
    15241 gtaggggcag cccttagtat catcggaaat attaccagcg gcctgtggtc attgagtcat
    15301 attttctggc attcccgggg cgactatttc gatttctcct ggggctggca cagccttcac
    15361 ccgatactct gggtaatcaa cattattttc agcatcatcg ccgccgtaaa ggctaatgag
    15421 ggcatctcct acaaataccc ctttaacctg cgcctcgtca aatagaaccc catttattat
    15481 tttattattt gattatttga gattttaaat aaagcgaaga ggccctccgt actatccgga
    15541 gggcctcttc gctttattta aaatctcaaa taatcaaata ataaaatgat tagtttttct
    15601 tcactggttt cattttggct ttctgcggtt tcttcacgtt ttctcctttg atgctggcgg
    15661 cgagttttaa tgcttcgtag gcatttacca ggcctccggt aacggagagg tcagcaaatt
    15721 ttattttctc gtcagagccg ggtttgttta cttccgtggt gccgtctgca aggggggtag
    15781 cgcttctttc caggatgtat ttcagctggc gggcactcag gtcagggtag cgggagagaa
    15841 ccagcgcagc cacgcctgct actacagggg ctgccatgct ggtgccgctg gcgctgccgt
    15901 atttgttgcc gccgggtatg gtagaataga tctgtacgcc gggggcgaag atgtctacat
    15961 gttttttacc gtagttggag aagccggcca ctttgtccgg gcccaggccg ctgctgctgg
    16021 cgcctaccgt gatgtagttg gtggggtggg tgccatccag gaaatccgtg ttcgggaagt
    16081 tgggaacaga atcgttgttg ttgccgtcgt tacctgcagc atgaacgatc agtacacctt
    16141 tcttttctgc atatctgatg gcatcgtcta cccattcctt gtgaggggag aagggtttac
    16201 caaagctcat gttgatgatc tgcgcaccgt tgtctaccgc atagcggata gccagggcaa
    16261 catccttatc cctttcatcg ccatcaggga ccgctttaac ggccattatg cgcacattgt
    16321 cggccacgcc atccataccc acgccattgt tccgtgcagc ggctataatg ccgcttacgt
    16381 gcgtaccgtg gaagccgaag gcgcccatca catcgttatt gccgtatttg ttgtctttga
    16441 tatcgtcgta gttatcgcct acaatcttct gcctgttttc gttgggagga gtttcagcgc
    16501 cttctgtctt gcgtttgagg tcactcatat aggcgtcgaa ttcatttttg aattcgttga
    16561 aggcggggct ttcttctccc gcgcttttca gcaggcgggt catgaagtta cgtgccagca
    16621 gtacatcctg gctggtggtc tggatgctgt caagtttgcc tacggtaaaa tcatcggtat
    16681 gcagataatt tttcaggatg gtttcgcatt tgttgacatt ctcctgcagt ttcaccatgg
    16741 acttgtactg catcatgctt tcgttgctgg gcttgtcaac ttttgccaca atacgttgcc
    16801 aggtggcata ttcggcagag tttttatcca gtgcggagtc ggggttaccg tatttatttt
    16861 tgaaacggta gtattcgcgg gaagcctcgt cggaatcttc tttcacgctg ccgccatctt
    16921 tgccgcccag gaagttccag ccatgtatat cgtcaatata accgttaccg tcatcgtctt
    16981 tgccgttacc cggaatttcg cgcggattgg tccataaaat gcctttcagg tcttcatgaa
    17041 gggtatcaat accggaatca atgacagcaa caataacagg ggtgcttttc tttcctttga
    17101 gcagttcttt gtaggctttc tctatgccgg ttccgtaaac gctgtcagta tcgtagctta
    17161 acaagtgcca gtttttggga agggttttgc cctgtgccgc tgttctggtg gtaaatgcag
    17221 tcatcattgc aacacaacct gccaggactg ccacctctcg actaaacaat ttcatgtact
    17281 ttaattttcc agtataaatg taagtaatgg ttaaattatc atgtaatgag taaaggtatt
    17341 aaaaaagggg cagaagacgg acatattaat gataaacgtg cgatatgccg gttaaccgga
    17401 ttttgactgc ggaatctatc ctgtaaggtt gaaagggaag gggggatagc ctccccggaa
    17461 gggggtaaaa gtggcccgga agggcacatg gaaaggaaaa aaagggcaaa agttatcgtg
    17521 atttacagaa attctgaaaa taatcctgcg gtgtattata cagcgggcat aacggaagaa
    17581 tcgctgaaaa tgccttgtgg taaagtattt ggtcggtatt ttaggtggaa gctcctctaa
    17641 aattaagtgt tagtagcaca aaagttgaat atgaaaattc agaaaaaagt ctaatattta
    17701 tagtcggaag aatatttaat ggcttcccgc cattggatat ttttctcata agcatggttt
    17761 ccgtttaacg aaaagcgggg ttctctaacc tcgctactat ttttaaaaac catgttttta
    17821 acgtcgatgt atgtagagac acacgaccag acagcgaaaa acggtgtgca tgatttttta
    17881 ccgtcttgct ataacgattt tctgactgtg attttatcaa ccgcttttaa aatctgatcg
    17941 gggggacagt cctgacatga aaattaaaag ctccggggcc aggcctcgga gctgagctcc
    18001 agagaagaaa tccacgctta cagctattac ataattaaac ttttaagaag aagaaggcga
    18061 tttattcttc caaaaagaaa cccgcctggc gtaatgccgg acgggtttca acattattgc
    18121 aaccgtgatt acaggtcaaa cttaatgccc tgtgccagcg gtaatttgtc ggagtagttg
    18181 atggtgttgg tctgacggcg catatatgct ttccaggagt cggaaccact ttctctgccg
    18241 cctccggttt ctttttcacc gccaaaagca ccgccgattt cagcgccgga agtaccgatg
    18301 tttacgttgg cgataccgca gtcagagccg gcgtgggaca ggaattgctc tgcctcgcgc
    18361 aggttcagcg tcatgatggc ggaggataat ccctgcggca catcattctg catggcgatc
    18421 gcttctgtga gcgtctggta tttcatcaca tagaggatcg gtgcgaaggt ctcgtgttgt
    18481 acaatatcgt aggtgttttc cactgccgcg atgcatggtt ttacgtagca gccggattca
    18541 aagccggcgc cttccagtac gccgccttcc acgaggaagg taccgccctg ttgcttcacc
    18601 tgttcgatcg tgtgaaggta tgctttcacg gcatccgtgt caatcagcgg acccacgtgg
    18661 ttgttttcat tgagcggatt accgatgcgc agttgtccgt aagcctttac cagccttgct
    18721 gtgaaggcat cgtacacgct ttcatggata atgagtctgc gggtagttgt gcaacgctgg
    18781 ccggcagtac ctaccgcgcc gaatacagcc ccgatcaggg acatatccag gtcggcatcc
    18841 tgagaaacga tgatcgcgtt gttaccgccc agttccagca gggagcggcc cagacgggcg
    18901 cccacagcgg cagccacgct cttgcccata cgggtggagc ctgtggcgga aaccagaggc
    18961 acgcggtgat caccagccat ccattcacct acttcgcggc cgccggtaac caggcaggaa
    19021 acgccttccg gtacgttgtt ggcagcaaat acggtttcga ctatacgttg acaggcgagt
    19081 gcggtcaccg gtgttttttc ggaaggcttc catacgcata cgttaccgca aacccatgac
    19141 aacattgagt tccagctcca taccgccacc gggaaattga aggcggaaat gataccggtg
    19201 ataccaatcg ggtgccattg ctcatacatg cggtggccgg gacgttcaga gtgcatggtt
    19261 aagccgtaga gctggcggga aagacctact gcaaaatcgc agatgtcgat catctcctgt
    19321 acttctccgt agccttcctg gaggctttta cccatttcat aggaaacgag gcggcccagg
    19381 tgttctttat gctgacgcag tgcatcgccg atctggcgta caacttcccc tctgcgtgga
    19441 gcgggccatt gacgccatgc ggcaaaggcc tggtgggcta cagcgatcac attatcgtag
    19501 tcctcccggg tagcgctttt cacggttgca atctttttat tgtcaaccgg tgaaaaggaa
    19561 acaatatcag ctccgccggc ggagagccag tgtttgccgg tgcttacgcc gctttgctgt
    19621 gcgccgatgc caaatgcctg taaaatatct tctgccattg tattttttgt tattaaacta
    19681 aattaggaac ttttttttgt ttgggtggca taagtgcttt cgaagatctt atcggcatta
    19741 ccggcttcga agccttcccg cctgtgctgc cgtttgattt cagctgccgg caggtgcgca
    19801 aattccggta gtacctttct ttcggcaaac tccacatagg agccggcaat cttaacggtg
    19861 tcgcctccgg caaaagtagc ttcaatcatt ctggctacgg tggcgctttg cagcagtctg
    19921 ccatcagggc tggttttgat tttgccgccg gcatcgttga ggatgaatcc atttttctcc
    19981 aggaaagcat tgaattcagc tactgtattg tatcccggag gcaggttatg tacgcttacc
    20041 gtaaaatggt tcaggtaata acggttgtaa ataacccagg cagcgtattc gctttccgct
    20101 gagagcgcct tgaaatctgc cagggtaggc gttctccaaa gaccgctatg taagaaggta
    20161 tctactgcct ggctgtcatc caggttcagt ctggttacag gatctacggt tacttcgtct
    20221 gtatagctgc ggatgatggc ctgtgcttcg gggctgagat cgtttacacg cagttcactg
    20281 atgaagatgc gcgggtactt cggctccggc ggcgcatacc accaggcgtc cagtttcttg
    20341 ccggcaaaat aatagtgatc cattttcgta tagccgtaat ggaggaatat tttctccagc
    20401 gactgtacgc ccagctgcgg tacgcccatc gttctgaaag cgatgtggtc attttctata
    20461 tcatccgcct ggctgatcag gccatcccgt accatggctg caattaccgc agctacatcc
    20521 ggtacccgct cctggtagcg gctcataagg ccgtttaata cttcttttaa catggctttg
    20581 tttttgaata gtcgcggctc cggcaggctt gctgcctacg cattactagt tataatattg
    20641 agcaaatctg ttattgatga ggtctttgaa atccacatct tcctggcgaa cgaagccatt
    20701 ggcaggcagt ttacctttag cgtggaggtc aattaccgca caggctgcgc cggctgtagt
    20761 cagctgaata gcggtaaaat cctttccttc aatttcctga ttgtatattt tcctggaata
    20821 ggaacgctga acggagcggc cgttgatagt gcctgacacg gatacaaata ccagtactac
    20881 gtcctggggc gtgaaaggaa tgctgtcttc catgatctct ttcagcatct ctctcttctt
    20941 gttcagcttc agttctgaca aaagtatttt ca
//
