LOCUS       NZ_CP028218            26296 bp    DNA     circular CON 22-JUN-2024
DEFINITION  Bacillus subtilis strain SRCM102756 chromosome, complete genome.
ACCESSION   NZ_CP028218
VERSION     NZ_CP028218.1
KEYWORDS    RefSeq.
SOURCE      Bacillus subtilis
  ORGANISM  Bacillus subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 4145782)
  AUTHORS   Jeong,D.-Y.
  TITLE     Bacillus subtilis SRCM102756 having antimicrbial activity species
            isolated from korea Soy sauce
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4145782)
  AUTHORS   Jeong,D.-Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-MAR-2018) Functionality Evaluation Team, Microbial
            Institute for Fermentation Industry, Minsokmaeul-gil 61-27, sunchang
            56048, Korea, Republic of
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. v3.0
            Expected Final Version            :: yes
            Genome Coverage                   :: 187.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009913595.1-RS_2024_06_22
            Annotation Date                   :: 06/22/2024 02:31:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,384
            CDSs (total)                      :: 4,263
            Genes (coding)                    :: 4,129
            CDSs (with protein)               :: 4,129
            Genes (RNA)                       :: 121
            rRNAs                             :: 10, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 84 of 134
            Pseudo Genes (incomplete)         :: 67 of 134
            Pseudo Genes (internal stop)      :: 16 of 134
            Pseudo Genes (multiple problems)  :: 29 of 134
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:18:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 330696
            Orig. end                         :: 356992
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP028218.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26296
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="2"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..26296
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26296
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16296](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16296)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            complement(42..2159)
                     /gene="pnp"
                     /locus_tag="C7M30_RS01780"
                     /old_locus_tag="C7M30_00362"
     CDS             complement(42..2159)
                     /EC_number="2.7.7.8"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pnp"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389551.1"
                     /locus_tag="C7M30_RS01780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M30_00362"
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="WP_003231897.1"
                     /transl_table=11
                     /translation="MGQEKHVFTIDWAGRTLTVETGQLAKQANGAVMIRYGDTAVLSTA
                     TASKEPKPLDFFPLTVNYEERLYAVGKIPGGFIKREGRPSEKAVLASRLIDRPIRPLFA
                     DGFRNEVQVISIVMSVDQNCSSEMAAMFGSSLALSVSDIPFEGPIAGVTVGRIDDQFII
                     NPTVDQLEKSDINLVVAGTKDAINMVEAGADEVPEEIMLEAIMFGHEEIKRLIAFQEEI
                     VAAVGKEKSEIKLFEIDEELNEKVKALAEEDLLKAIQVHEKHAREDAINEVKNAVVAKF
                     EDEEHDEDTIKQVKQILSKLVKNEVRRLITEEKVRPDGRGVDQIRPLSSEVGLLPRTHG
                     SGLFTRGQTQALSVCTLGALGDVQILDGLGVEESKRFMHHYNFPQFSVGETGPMRGPGR
                     REIGHGALGERALEPVIPSEKDFPYTVRLVSEVLESNGSTSQASICASTLAMMDAGVPI
                     KAPVAGIAMGLVKSGEHYTVLTDIQGMEDALGDMDFKVAGTEKGVTALQMDIKIEGLSR
                     EILEEALQQAKKGRMEILNSMLATLSESRKELSRYAPKILTMTINPDKIRDVIGPSGKQ
                     INKIIEETGVKIDIEQDGTIFISSTDESGNQKAKKIIEDLVREVEVGQLYLGKVKRIEK
                     FGAFVEIFSGKDGLVHISELALERVGKVEDVVKIGDEILVKVTEIDKQGRVNLSRKAVL
                     REEKEKEEQQS"
     gene            complement(2332..2601)
                     /gene="rpsO"
                     /locus_tag="C7M30_RS01785"
                     /old_locus_tag="C7M30_00363"
     CDS             complement(2332..2601)
                     /GO_component="GO:0005840 - ribosome [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpsO"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010898561.1"
                     /locus_tag="C7M30_RS01785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M30_00363"
                     /product="30S ribosomal protein S15"
                     /protein_id="WP_003220957.1"
                     /transl_table=11
                     /translation="MAITQERKNQLINEFKTHESDTGSPEVQIAILTDSINNLNEHLRT
                     HKKDHHSRRGLLKMVGKRRNLLTYLRNKDVTRYRELINKLGLRR"
     misc_feature    2727..2740
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.31"
                     /tool="antismash"
     gene            complement(2758..3708)
                     /gene="ribF"
                     /locus_tag="C7M30_RS01790"
                     /old_locus_tag="C7M30_00364"
     CDS             complement(2758..3708)
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /codon_start=1
                     /gene="ribF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389549.1"
                     /locus_tag="C7M30_RS01790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M30_00364"
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="WP_160243908.1"
                     /sec_met_domain="CTP_transf_like (E-value: 1.3e-05,
                     bitscore: 23.4, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTIHMTHPHHLIKEEQAKSVMALGYFDGVHLGHQKVIGTAKQIA
                     EEKGLTLAVMTFHPHPSHVLGRDKEPKDLITPLEDKINQIEQLGTEVLYVVKFNEVFAS
                     LSPKQFIDQYIIGLNVRHAVAGFDFTYGKYGKGTMETMPDDLDGKAGCTMVEKLTEQDK
                     KISSSYIRTALQNGDVELANVLLGQPYFIKGIVIHGDKRGRTIGFPTANVGLNNSYIVP
                     PTGVYAVKAEVNGEVYNGVCNIGYKPTFYEKRPEQPSIEVNLFDFDQEVYGAAIKIEWY
                     KRIRSERKFNGIKELTEQIEKDKQEAIRYFSNLRK"
     gene            complement(3727..4656)
                     /gene="truB"
                     /locus_tag="C7M30_RS01795"
                     /old_locus_tag="C7M30_00365"
     CDS             complement(3727..4656)
                     /EC_number="5.4.99.25"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /GO_process="GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="truB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389548.1"
                     /locus_tag="C7M30_RS01795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M30_00365"
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="WP_160243909.1"
                     /transl_table=11
                     /translation="MVNGVLLLHKPVGMTSHDCVMKIRKLLKTKKVGHTGTLDPEVSGV
                     LPICVGRATKIVEYLTEKSKTYDAEITLGFSTTTEDQTGETVETKPVNHDIDKADVEKV
                     LNSLKGKQEQIPPMYSAVKVNGKKLYEYARAGIEVERPKRMITIEDIALTTEIKHHGET
                     ASFRFTVTCSKGTYVRTLAVMIGEKLGYPAHMSHLIRTASGDFSLDECFTFDELEAQAQ
                     SGTVEEHTVPIKRALNHLPKWIISDTLAKKVENGALLETPEQFSEMTSEDRIAVFTESG
                     TCLAIYFPHPAKKGLLKPAKVLMQKSEQ"
     gene            complement(4738..5091)
                     /gene="rbfA"
                     /locus_tag="C7M30_RS01800"
                     /old_locus_tag="C7M30_00366"
     CDS             complement(4738..5091)
                     /GO_process="GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /gene="rbfA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389547.1"
                     /locus_tag="C7M30_RS01800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M30_00366"
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="WP_009967251.1"
                     /transl_table=11
                     /translation="MSMRANRVGEQMKKELGDIISRKLKDPRIGFLTVTDVRVSGDLQI
                     AKVYISVLGDEKKREEALKGLAKAKGFIRSEIGSRIRLRKTPEIEFEFDESIDYGNRIE
                     TLIHELHSEKPSE"
     gene            complement(5108..5386)
                     /locus_tag="C7M30_RS01805"
                     /old_locus_tag="C7M30_00367"
     CDS             complement(5108..5386)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003328897.1"
                     /locus_tag="C7M30_RS01805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M30_00367"
                     /product="DUF503 domain-containing protein"
                     /protein_id="WP_003231905.1"
                     /transl_table=11
                     /translation="MIGFAECECIIYDAGSLKEKRAVLKRVLTRVQNKFNVSISEIGYQ
                     DTWQRTSFGIAAVSSSRVQTEKELQRVLAFIDSFPEIERTITRTEWF"
     gene            complement(5383..7533)
                     /gene="infB"
                     /locus_tag="C7M30_RS01810"
                     /old_locus_tag="C7M30_00368"
     CDS             complement(5383..7533)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003743 - translation initiation factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_process="GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="infB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389545.1"
                     /locus_tag="C7M30_RS01810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M30_00368"
                     /product="translation initiation factor IF-2"
                     /protein_id="WP_014479801.1"
                     /transl_table=11
                     /translation="MAKMRVYEYAKALNVSSKEILTALKNMDLEVNNHMAMLEEKAIKK
                     LDAKYKKGGAAAKSQKPAETNKNKQPQGVNQQSAGNQPNKIRDGKKNDVQNNQFNKNKK
                     NNNNKKNKRNNNNNKNQHQQKPVKPKKELPEKITFSGTLTVGALAEELGKEPSEIIKKL
                     MLLGVMATINQELDKDTIELIASEYGVETEEVIVLEETELEKYEEPDNEEDLEIRPPVV
                     TIMGHVDHGKTTLLDSIRKTKVVEGEAGGITQHIGAYQIEENGKKITFLDTPGHAAFTT
                     MRARGAEVTDITILVVAADDGVMPQTVEAINHAKAAEVPIIVAVNKIDKESANPDRVMQ
                     ELTEYGLVPEAWGGETIFVPLSALTGKGIDELVEMILLVSEVEELKANPNRQAKGTVIE
                     AELDKGRGSVATLLVQTGTLHVGDPIVVGNTFGRVRAMVNDIGRRVKTAGPSTPVEITG
                     LNDVPQAGDQFLVFKDEKTARSVGEARASKQLEEQRSDKAKLSLDDLFEQIKQGDVKDI
                     NLIVKADVQGSAEALTAALQKIEVEGVKVKIIHTGVGAITESDIILASASNAIVIGFNV
                     RPDGNAKSTAEAENVDIRLHRIIYKVIDEIEAAMKGMLDPEYEEKVIGQVEVRQTFKVS
                     KIGTIAGGYVTEGTITRDSGLRLIRDGVVIFEGEVDVLKRFKDDVKEVSQGYECGITIK
                     KYNDIREGDILEAFVMQEIERT"
     gene            complement(7553..7855)
                     /gene="rulQ"
                     /locus_tag="C7M30_RS01815"
                     /old_locus_tag="C7M30_00369"
     CDS             complement(7553..7855)
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /codon_start=1
                     /gene="rulQ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389544.1"
                     /locus_tag="C7M30_RS01815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M30_00369"
                     /product="YlxQ family RNA-binding protein"
                     /protein_id="WP_003220946.1"
                     /transl_table=11
                     /translation="MSGMEWFPLLGLANRARKVVSGEDLVIKEIRNARAKLVLLTEDAS
                     SNTAKKVTDKCNYYKVPYKKVESRAVLGRSIGKEARVVVAVTDQGFANKLISLLD"
     gene            complement(7857..8132)
                     /gene="rulR"
                     /gene_synonym="ylxR"
                     /locus_tag="C7M30_RS01820"
                     /old_locus_tag="C7M30_00370"
     CDS             complement(7857..8132)
                     /codon_start=1
                     /gene="rulR"
                     /gene_synonym="ylxR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389543.1"
                     /locus_tag="C7M30_RS01820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M30_00370"
                     /product="glucose-induced regulator RulR"
                     /protein_id="WP_009967250.1"
                     /transl_table=11
                     /translation="MNKHKKIPLRKCVVTGEMKPKKELIRVVRSKEGEISVDPTGKKNG
                     RGAYLTLDKECILAAKKKNTLQNQFQSQIDDQIFDELLELAEKVKK"
     gene            complement(8146..9261)
                     /gene="nusA"
                     /locus_tag="C7M30_RS01825"
                     /old_locus_tag="C7M30_00371"
     CDS             complement(8146..9261)
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_process="GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /gene="nusA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389542.1"
                     /locus_tag="C7M30_RS01825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M30_00371"
                     /product="transcription termination factor NusA"
                     /protein_id="WP_003231912.1"
                     /transl_table=11
                     /translation="MSSELLDALTILEKEKGISKEIIIEAIEAALISAYKRNFNQAQNV
                     RVDLNRETGSIRVFARKDVVDEVYDQRLEISIEEAQGIHPEYMVGDVVEIEVTPKDFGR
                     IAAQTAKQVVTQRVREAERGVIYSEFIDREEDIMTGIVQRLDNKFIYVSLGKIEALLPV
                     NEQMPNESYKPHDRIKVYITKVEKTTKGPQIYVSRTHPGLLKRLFEIEVPEIYDGTVEL
                     KSVAREAGDRSKISVRTDDPDVDPVGSCVGPKGQRVQAIVNELKGEKIDIVNWSSDPVE
                     FVANALSPSKVLDVIVNEEEKATTVIVPDYQLSLAIGKRGQNARLAAKLTGWKIDIKSE
                     TDARELGIYPRELEEDDEPLFTEPETAESDE"
     gene            complement(9296..9766)
                     /gene="rimP"
                     /locus_tag="C7M30_RS01830"
                     /old_locus_tag="C7M30_00372"
     CDS             complement(9296..9766)
                     /GO_process="GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /gene="rimP"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389541.1"
                     /locus_tag="C7M30_RS01830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M30_00372"
                     /product="ribosome maturation factor RimP"
                     /protein_id="WP_003231915.1"
                     /transl_table=11
                     /translation="MSKKVTDTVQEMAQPIVDSLQLELVDIEFVKEGQSWFLRVFIDSD
                     DGVDIEECAKVSEALSEKLDEADPISQNYFLEVSSPGAERPLKKKADFEKSLGKNVYIK
                     TYEPIDGVKVFEGELAEFDGQTVTVEITIKTRKKRINIPYEKIANARLAVTF"
     misc_feature    9805..9818
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.81"
                     /tool="antismash"
     gene            complement(10001..11230)
                     /locus_tag="C7M30_RS01835"
                     /old_locus_tag="C7M30_00373"
     CDS             complement(10001..11230)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="C7M30_RS01835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M30_00373"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_041850824.1"
                     /sec_met_domain="LANC_like (E-value: 1.2e-59, bitscore:
                     199.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLNNYIDKIIIKTSKQISDLQLVLNLQRLDDISVASGISSVCILF
                     AELDYTFPNRGWDRIGHEYLIHIKKKLEGMEDYSPSCLGGMGGIGFCILALSKNGNRYR
                     NFLTDFNLYYFDIIKKHIEEFKDLSSLQKNDLFLYETIYGFAGIGRYLLFFRDQRESRD
                     LLEKILVLITRMANKNVNSLADEKYVLDCGLAHGVSGPLSLLSLSYINNIIVEGQLDAI
                     KKISNFLIKTKTKSANGYLFPNGIILNEKNKDQTVDITTRDAWCYGSPGTCRALLLAKE
                     ATGDAKYSNCAVTVFKDVIKRNFEQQKNYSPTFCHGLSGLLTITFLFNESIRDPKFKSY
                     QIYLVKKLLGYYNDNNVLGFQNIERDNLNKEIVSDELGILNGVTGVLLTLLAFRNQMTY
                     TRWESILLLN"
     gene            complement(11312..13123)
                     /locus_tag="C7M30_RS01840"
                     /old_locus_tag="C7M30_00374"
     CDS             complement(11312..13123)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="C7M30_RS01840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M30_00374"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_041850825.1"
                     /transl_table=11
                     /translation="MSKFYNVTYKEVISSFNNWPKLYKIFLKVDKISFFQIIIIAVISG
                     FIPPSLLLLNQSLLNNLQRETQINKVLLIFILLIVVYLVQVIVNQYKQYKEEIFANKLA
                     YFINLEILKKTKILELPDFENPHIYDQIQRVTSESSYRPFQIFTEILNILTNIITIIST
                     SIIIIIWKWWVVILLFLTPIISSIFFVKLGKKEYEIEWERTPLRRKIYYYIFLMTRDFN
                     IKEIKLFNLSDLLISRYEKINKVFLKTDKEMAQRKMKVSTIFETVNQLIVGGIMLYIIL
                     KVFSKEIMIGTMMALIQGVISSQTALKTLMQGVFSVYENNLYVNDFFEFVKNRKLNNDT
                     KLEEKIQLTEINKITFNNVSFKYPNKNNYALKKISFELKKGETIAIVGGNGSGKSTLIK
                     LICRLYDGFEGEILINSIPIEKYSIESIRAQTSIIFQDFIKYEFSIRENIGFGNYNEMK
                     NQDFLEYAAYISGANKIINKYPDRFDSQLGKMFNKGHQLSGGEWQKMAISRAIFKKASL
                     YMMDEPSSALDIYSEQELFIKYNEFLKNKIGLFITHRFNTVQLASRILVMNNGEIIECG
                     THKELLQNKGMYYDLYNQQKKVFYSGL"
     gene            complement(13120..16296)
                     /locus_tag="C7M30_RS01845"
                     /old_locus_tag="C7M30_00375"
     CDS             complement(13120..16296)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="C7M30_RS01845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M30_00375"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_041850826.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.5e-149,
                     bitscore: 497.1, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 4.4e-07,
                     bitscore: 28.5, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 9.6e-34, bitscore:
                     115.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSLKKDSLKNIEQKWFSLDSFFIRTPTLSLTFLENYLHKMINGK
                     ESYSNWVKDLINNPIFMEAIYIASPSLYENLKYWKNITDKKRKEQIAISLNNYLLRMTS
                     RTTPFGLFSSVTVGRFENETSINIDPLVHNIKKCNPDMNWLYKLIKKLEKENSIFLELN
                     VKFNNLVEKVGNRYFLSYNSKIDSARQNNITNDISSIIVSPPIEIIEKLTQEPLKIKNI
                     LRYLKKEYSSVTSEKILSLIHNLVDQDYLITDLRPSLLEKSPFNYVINKIKSIEKQDLQ
                     YILQELLSIQAKINYYETLPIGEGLNEVNEIEKLMSNLVVSDIYLQVNLSLNNKSEIKL
                     SNNVKKDLIELTECLEYFSITNNKPRHLKNYLNEFIDKYGEHREVELLELLNNDIGLGS
                     PASYKNPTSTREFIYKSNQKLENYLLRKLLNSIKENEQEIEITLEELKHLNKEKNISGQ
                     NNFVKSFEIFGNIVADNIDSFNKGKYTIFLNSENPVSNFAGKAAGRFTDLLKDKTNVKQ
                     FYDQQTICEHYINAEMSYTPNNGKIANIMMVDNFSDYEINLNNFCSEENETIPIEDIVV
                     GVEEDLFYFKSKNLNKRINISVNSLVNMDITPNVFRFIQEASLFNDQYLTGFNWGRLIE
                     SEFLPRVKFKKTILSPAMWNFNLSDHITEKPNYDEWLKIFKRWAKKWSIPKSVYLVEGD
                     EKLFLNLDVHLHLKILYKKIQKMKIIRLIESEINLSKSWAQDRNKNKYNIEFIFPLIQN
                     KNNNSIGKTKKNKPIIYTNSILTKKQIGSDWLYFKLYFNSFRDEEIIADHIPSFLNQLI
                     NNNQLINKYFYVRYLDDKPHIRLRIQGDPNILLSTVLIKMKDWTSNLIEGGLINKIELS
                     CYEREIERYGGPDFIDICETLFYYDSICVSELFNFLSYTTNELFDKETIAVLSVIFYLE
                     EIGFDYNQQLNLFERILENNKFPKEFRLKKDYLVFLCNSNLNWSNLRKSEDGNKLISIF
                     EKRKKIINHASEEFSVKSNYLYSPTKDIWLSIIHMHLNRLLGVDREKEKNIMLLVKYTL
                     KNLKYQKGIL"
     aSDomain        complement(15523..15798)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_C7M30_RS01845_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="2.90E-09"
                     /identifier="RREFam001.1"
                     /label="C7M30_RS01845"
                     /locus_tag="C7M30_RS01845"
                     /protein_end="258"
                     /protein_start="166"
                     /score="28.5"
                     /tool="antismash"
                     /translation="NNLVEKVGNRYFLSYNSKIDSARQNNITNDISSIIVSPPIEIIEK
                     LTQEPLKIKNILRYLKKEYSSVTSEKILSLIHNLVDQDYLITDLRPS"
     gene            complement(16378..16557)
                     /locus_tag="C7M30_RS01850"
                     /old_locus_tag="C7M30_00376"
     CDS             complement(16378..16557)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C7M30_RS01850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C7M30_00376"
                     /product="hypothetical protein"
                     /protein_id="WP_041850827.1"
                     /transl_table=11
                     /translation="MEKDIFDLDLKIQTSKSNVEPNSIRLTFGCSGGVASKALCSRAMC
                     DGIVITKNYGYCDA"
     CDS_motif       complement(16492..16557)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MEKDIFDLDLKIQTSKSNVEPN"
                     /locus_tag="C7M30_RS01850_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(16378..16491)
                     /prepeptide="core"
                     /locus_tag="C7M30_RS01850_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="13.90"
                     /molecular_weight="3724.3"
                     /monoisotopic_mass="3721.8"
                     /core_sequence="SIRLTFGCSGGVASKALCSRAMCDGIVITKNYGYCDA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MEKDIFDLDLKIQTSKSNVEPN"
                     /leader_location="[16491:16557](-)"
                     /alternative_weights="3742.3"
                     /alternative_weights="3760.4"
     misc_feature    complement(16574..16591)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: medium, score: 18.97"
                     /tool="antismash"
     gene            complement(16704..21017)
                     /gene="polC"
                     /locus_tag="C7M30_RS01855"
                     /old_locus_tag="C7M30_00377"
     CDS             complement(16704..21017)
                     /EC_number="2.7.7.7"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_function="GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /gene="polC"
                     /gene_functions="other (smcogs) SMCOG1194: DNA polymerase
                     III subunit alpha"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389540.1"
                     /locus_tag="C7M30_RS01855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M30_00377"
                     /product="PolC-type DNA polymerase III"
                     /protein_id="WP_015715890.1"
                     /transl_table=11
                     /translation="MEQLSVNRRQFQILLQQINMTDDTFMTYFEHGEIKKLTIHKASKS
                     WHFHFQFKSLLPFQIYDTLTTRLTQSFAHIAKVTSSIEVQDAEVSESIVQDYWSRCIEE
                     LQGISPPIISLLNQQKPKLKGNKLIVKTKTDTEAAALKNKYSSMIQAGYRQFGFPDLQL
                     DAEIFVSEQEVQKFREQKLAEDQERAMQALIEMEKKDKESDEDQAPSGPLVIGYQIKDN
                     EEIRTLDSIMDEERRITVQGYVFDVETRELKSGRTLCIFKITDYTNSILIKMFAREKED
                     AALMKSLKKGMWVKARGSIQNDTFVRDLVMIANDVNEIKAKTREDSAPEGEKRVELHLH
                     SPMSQMDAVTGIGKLVEQAKKWGHEAIALTDHAVVQSFPDAYSAAKKHGIKMIYGMEAN
                     LVDDGVPIAYNAAHRLLEEETYVVFDVETTGLSAVYDTIIELAAVKVKGGEIIDKFEAF
                     ANPHRPLSATIIELTGITDDMLQDAPDVVDVIRDFREWIGDDILVAHNASFDMGFLNVA
                     YKKLLEVDKAKNPVIDTLELGRFLYPEFKNHRLNTLCKKFDIELTQHHRAIYDTEATAY
                     LLLKMLKDAAEKGIQYHDELNENMGQSNAYQRSRPYHATLLAVNSTGLKNLFKLVSLSH
                     IHYFYRVPRIPRSQLEKYREGLLIGSACDRGEVFEGMMQKSPEEVEDIASFYDYLEVQP
                     PEVYRHLLELELVRDEKALKEIIANITKLGEKLNKPVVATGNVHYLNDEDKIYRKILIS
                     SQGGANPLNRHELPKVHFRTTDEMLEAFSFLGEKKAKEIVVTNTQKVASLVDDIKPIKD
                     DLYTPKIEGADEEIREMSYQRARSIYGEELPEIVEARIEKELKSIIGHGFAVIYLISHK
                     LVKRSLDDGYLVGSRGSVGSSLVATLTEITEVNPLPPHYVCPECQHSEFFNDGSVGSGF
                     DLPDKTCPHCGTPLKKDGHDIPFETFLGFKGDKVPDIDLNFSGEYQPQAHNYTKVLFGE
                     DNVYRAGTIGTVAEKTAYGYVKGYAGDNNLHMRGAEIDRLVQGCTGVKRTTGQHPGGII
                     VVPDYMDIYDFSPIQFPADATGSEWKTTHFDFHSIHDNLLKLDILGHDDPTVIRMLQDL
                     SGIDPKTIPTDDPEVMKIFQGTESLGVTEEQIGCKTGTLGIPEFGTRFVRQMLEDTKPT
                     TFSELVQISGLSHGTDVWLGNAQELIHNNICELSEVIGCRDDIMVYLIYQGLEPSLAFK
                     IMEFVRKGKGLTPEWEEEMKNNNVPDWYIDSCKKIKYMFPKAHAAAYVLMAVRIAYFKV
                     HHALLYYAAYFTVRADDFDIDTMIKGSTAIRAVMEDINAKGLDASPKEKNLLTVLELAL
                     EMCERGYSFQKVDLYRSSATEFIIDGNSLIPPFNSIPGLGTNAALNIVKAREEGEFLSK
                     EDLQKRGKVSKTILEYLDRHGCLESLPDQNQLSLF"
     misc_feature    21100..21109
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            complement(21126..22820)
                     /gene="proS"
                     /locus_tag="C7M30_RS01860"
                     /old_locus_tag="C7M30_00378"
     CDS             complement(21126..22820)
                     /EC_number="6.1.1.15"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="proS"
                     /gene_functions="other (smcogs) SMCOG1162: threonyl-tRNA
                     synthetase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389539.1"
                     /locus_tag="C7M30_RS01860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M30_00378"
                     /product="proline--tRNA ligase"
                     /protein_id="WP_003231918.1"
                     /transl_table=11
                     /translation="MRQSLTLIPTLREVPADAEAKSHQLLLRAGFIRQNTSGVYSYMPL
                     AYKVIQNIQQIVREEMEKIDAVEMLMPALQQAETWQESGRWYTYGPELMRLKDRHGREF
                     ALGATHEEVITSLVRDEVKSYKRLPLTLYQIQSKFRDEKRPRFGLLRGREFIMKDAYSF
                     HASAESLDETYQKMYEAYSNIFARCGINVRPVIADSGAMGGKDTHEFMALSAIGEDTIA
                     YSDESQYAANIEMAEVLHQEVPSDEEPKALEKVHTPNVKTIEELTAFLQVSAEACIKSV
                     LFKADDRFVLVLVRGDHEVNDIKVKNLLHAEVVELATHEEVIQQLGTEPGFVGPVGIHQ
                     DVEVYADQAVKAMVNAVAGANEGDHHYKNVNVNRDAQIKEFADLRFIKEGDPSPDGKGT
                     IRFAEGIEVGQVFKLGTRYSEAMNATYLDENGRAQPMLMGCYGIGVSRTLSAIAEQHHD
                     EKGLIWPKSVAPYDLHILALNMKNDGQRELAEKLYADLKAEGYEVLYDDRAERAGVKFA
                     DSDLIGLPIRITVGKRADEGIVEVKIRQTGESTEISVDELSAFISKQ"
     gene            complement(22853..24121)
                     /gene="rseP"
                     /locus_tag="C7M30_RS01865"
                     /old_locus_tag="C7M30_00379"
     CDS             complement(22853..24121)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="rseP"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M50"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389538.1"
                     /locus_tag="C7M30_RS01865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M30_00379"
                     /product="RIP metalloprotease RseP"
                     /protein_id="WP_085186057.1"
                     /sec_met_domain="Peptidase_M50 (E-value: 1.2e-83, bitscore:
                     278.2, seeds: 56, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFVNTVIAFIIIFGTLVFFHELGHLLLAQRAGILCREFAIGFGPK
                     IFSFKKNETVYTIRLLPVGGFVRMAGEDPEMIEVKPGYTVGLLFNKEDQVEKVIINQKE
                     KYPDALVIEVETADLEHDMKITGYEQGKEDELSSFTVSETSFFIVDGEEVQIAPYNRQF
                     GSKPVWQRIKAIAAGPIMNFILAYVILVMLGLIQGVPSNEPMLGQLTDNGRAAEAGLKE
                     GDYIQSINGEKMRSWTDIVSAVKENPEKEMDVAVKRDNKTLHISVTPEAVKDENKKTIG
                     RFGSYAPTEKGVLSAVAYGATSTVDIGNQILETFGNLVTGQFKINMLAGPVGIYDMTDQ
                     VAKTGLVNLVRFAAFLSINLGIVNLLPIPALDGGRLLFLFIEAIRGKPINREKEAFVVF
                     IGVAFLMLLMLVVTWNDIQRLFL"
     gene            complement(24128..25279)
                     /gene="dxr"
                     /locus_tag="C7M30_RS01870"
                     /old_locus_tag="C7M30_00380"
     CDS             complement(24128..25279)
                     /EC_number="1.1.1.267"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0030604 - 1-deoxy-D-xylulose-5-phosphate
                     reductoisomerase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="dxr"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389537.2"
                     /locus_tag="C7M30_RS01870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M30_00380"
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="WP_003245155.1"
                     /transl_table=11
                     /translation="MKNICLLGATGSIGEQTLDVLRAHQDQFQLVSMSFGRNIDKAVPM
                     IEVFQPKFVSVGDLDTYHKLKQMSFSFECQIGLGEEGLIEAAVMEEVDIVVNALLGSVG
                     LIPTLKAIEQKKTIALANKETLVTAGHIVKEHAKKYDVPLLPVDSEHSAIFQALQGEQA
                     KNIERLIITASGGSFRDKTREELESVTVEDALKHPNWSMGAKITIDSATMMNKGLEVIE
                     AHWLFDIPYEQIDVVLHKESIIHSMVEFHDKSVIAQLGTPDMRVPIQYALTYPDRLPLP
                     DAKRLELWEIGSLHFEKADFDRFRCLQFAFESGKIGGTMPTVLNAANEVAVAAFLAGKI
                     PFLAIEDCIEKALTRHQLLKKPSLADIQEVDKDTRGYVNSILT"
     gene            complement(25341..26150)
                     /gene="cdsA"
                     /locus_tag="C7M30_RS01875"
                     /old_locus_tag="C7M30_00381"
     CDS             complement(25341..26150)
                     /EC_number="2.7.7.41"
                     /codon_start=1
                     /gene="cdsA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389536.1"
                     /locus_tag="C7M30_RS01875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M30_00381"
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="WP_003231924.1"
                     /transl_table=11
                     /translation="MVDMKQRILTGVLAAIVFLFLVIVGKLPFTILIYAMGSVALFELL
                     RMKKLKLVSLPGLIGLLLLWMFLLPSQYSFFEADGISKMEIALFAVLLLLTYTVLVKNT
                     FTFDEVGFITLAAIYIGMCFHYFIEIRNLDQYGLTYIFYACVVIWSTDSGAYFVGKSLG
                     KRKLWPEISPNKTVEGFAGGIVIALVLATIFQLVAQLPIPYIYLLLITLFLSVFGQLGD
                     LVESALKRHYDVKDSGNILPGHGGILDRFDSFLFVMPFLYFLLALFS"
ORIGIN
        1 ataaagaagc cgggtctccc aggctccttt tatgttttca tttaagattg ttgttcttct
       61 ttttctttct cttcacggag caccgcttta cgggacaaat tcactcgtcc ttgtttatca
      121 atttcagtga ctttgacaag aatctcgtct ccgattttta caacatcttc aactttccct
      181 acgcgttcaa gcgcaagctc tgaaatgtgc accaaaccgt cttttccgct gaaaatttca
      241 acgaaagccc cgaatttttc aatccgtttc actttaccta ggtaaagttg gccgacttca
      301 acctctctaa caaggtcttc gatgattttt ttcgcttttt ggttgccgct ttcatctgta
      361 gaggaaataa agattgtgcc gtcctgctca atatcaattt taacaccggt ttcttcgatg
      421 atcttattga tttgttttcc gcttggtccg atgacatcgc ggattttatc aggattaatg
      481 gtcattgtta agatcttagg cgcatatcga gaaagctctt ttcttgattc gcttaatgtt
      541 gcaagcatgc tgttgaggat ttccattctg ccctttttcg cctgctgaag cgcttcttca
      601 agaatctctc tggaaaggcc ttcaatttta atgtccattt gcagggccgt tacgcctttt
      661 tcagttcccg ctactttaaa gtccatatct ccgagcgcgt cttccatgcc ttggatgtca
      721 gtcaagacag tgtaatgttc gcctgatttg acaagaccca tcgcaatacc agcaactggc
      781 gctttaatcg gtacaccagc atccatcatt gcaagtgtgc ttgcgcaaat gcttgcttga
      841 gatgtagaac cgtttgattc aagcacttct gaaacaagac ggacagtata agggaagtct
      901 ttttcagacg gaataactgg ctcaagcgca cgctcaccca gtgctccgtg tccgatttca
      961 cgacgtcccg gtccgcgcat cggtcctgtt tccccaacgc tgaattgcgg gaagttgtaa
     1021 tgatgcataa accgtttcga ctcttcgaca cctaagccgt caaggatttg cacatctccc
     1081 agagcaccta gcgtacatac gctgagggcc tgagtttgtc cccttgtaaa tagacctgaa
     1141 ccgtgcgttc ttggcaagag gccaacctct gaagagagcg ggcggatttg atcgacaccg
     1201 cggccatccg gtcttacttt ctcttcagta atcaggcggc gaacttcatt tttcaccagc
     1261 ttggataaaa tctgcttcac ttgcttgatt gtgtcttcat catgttcttc atcctcgaat
     1321 tttgccacaa ctgcgttctt cacttcgtta atggcatctt cacgggcatg cttttcatga
     1381 acttggatgg ctttcagcag atcctcttct gccaaagctt ttactttttc attaagctct
     1441 tcatcaattt caaagagctt aatttcagat ttctctttgc cgactgctgc aacaatttct
     1501 tcttggaatg caatcaggcg tttaatctct tcatggccga acataatggc ctcaagcatg
     1561 atttcctcag gaacttcgtc cgctcccgct tctaccatgt taatcgcatc tttcgtgccg
     1621 gcaacgacaa gattgatgtc gcttttttca agctgatcga ctgtcgggtt aatgataaat
     1681 tgatcatcaa tgcgtccgac agtcacccct gcaatcggtc cttcaaacgg aatatccgat
     1741 acagaaagtg caagagatga accgaacatg gcagccattt ctgaagagca gttttggtca
     1801 acactcatga caatgctgat gacttgaact tcattacgga atccatcggc aaacaaagga
     1861 cggatcggac ggtcaattaa acggctggca agaaccgctt tttcacttgg acgtccttct
     1921 cttttaataa atccgcccgg aattttccct accgcatata atctttcttc atagtttaca
     1981 gtaagaggga agaaatcaag cggtttaggt tcttttgaag cggttgctgt actaagtact
     2041 gctgtatcac cgtagcggat catcacagca ccatttgcct gtttggcaag ctggccggtt
     2101 tcaacagtaa gcgttcttcc ggcccaatct atggtaaaga catgtttttc ttgtcccata
     2161 caattacgaa ctcctctctt cgttgtgtga aataatcaat tactcctatt atgaacgaaa
     2221 tgaattgaac atatcaatgt caaagtagta tgtaaaagga tttcaatgat ttgttataag
     2281 aaatttcgct ttaatacgat aaaaaagcgg gaatcctccc gctttttacg attatcgacg
     2341 taagcctagt ttgttaatta actcacggta acgagttacg tctttattac gcagatacgt
     2401 aagaagatta cgacgcttac ctaccatttt aagaagaccg cgacgtgagt ggtggtcttt
     2461 cttgtgagta cgtaaatgct cgttcaagtt gttaattgag tcagttagga tagcgatctg
     2521 aacttctgga gatccagtat cagattcgtg tgttttgaac tcattgatga gttggttttt
     2581 acgctcttga gtaattgcca tcctgtttca cctccaaatc atatttagcc ccagttacct
     2641 agcaaccgtc ggtgacttcg gattgccaag caatggtttt aagactacga aaactatcat
     2701 actaaaaatc gtgcctatat gcaaatattt tagaataaaa tttgcgtgcg ttgcaagtta
     2761 tttccgcaaa ttgctgaaat aacggatggc ttcctgctta tctttctcaa tttgctctgt
     2821 taattctttg atgccattga atttccgctc gctccgaatc cgtttgtacc attcgatttt
     2881 tatagcggct ccatatacct cttgatcgaa atcaaacaga ttgacctcga tggaaggctg
     2941 ctcagggcgc ttttcataaa acgttggctt atagccaata ttgcaaacgc cattgtaaac
     3001 ttcgccgttc acttccgctt ttacggcata tacacctgtg ggcggaacga tatagctgtt
     3061 atttaaaccg acatttgctg tcggaaaacc gatggtccgc cctcttttat caccatgaat
     3121 gacaattcct ttaataaaat atggctgtcc aagcaagaca ttcgccaatt caacatctcc
     3181 gttttgaagc gcggtacgga tatacgaaga actgattttt ttatcctgct ccgtcaattt
     3241 ttctaccatt gtgcacccag cttttccgtc taaatcatcc ggcatggtct ccattgttcc
     3301 cttgccgtat tttccgtacg taaagtcaaa gcctgccact gcgtgccgca cattaagacc
     3361 gataatatac tggtctataa actgcttagg agaaagagaa gcaaacactt cattaaattt
     3421 aacgacatac agaacttctg tacctaattg ttcaatttga tttattttgt cttcaagagg
     3481 cgtaatcaga tccttaggtt ccttatctct gcccaacacg tgagaaggat ggggatgaaa
     3541 ggtcatcaca gccaatgtca gacctttttc ttcggctatt tgcttcgctg tgccgattac
     3601 cttttgatgc ccgagatgaa cgccgtcaaa atatcctaac gccatcactg attttgcctg
     3661 ctcctctttt attaaatgat gaggatgtgt catatgtatc gtcttcacag aacggtcacc
     3721 ttttttctat tgttcgcttt tttgcatcaa tacttttgcc ggctttaaca gccctttttt
     3781 tgcaggatga gggaaataga tcgccaagca ggttccggat tcagtaaaga cggcaatacg
     3841 gtcttcactt gtcatttcag aaaactgctc gggcgtctca agcaaagccc cattttctac
     3901 tttcttagct aatgtatcac ttatgatcca tttcggcaaa tgattgagcg cacgtttaat
     3961 aggaactgta tgctcttcca cggttccgga ttgggcctgt gcttcgagct catcaaaagt
     4021 aaagcattcg tcgagagaaa aatctccgga tgccgtacgg attaaatgag acatatgagc
     4081 cggatatccg agcttttctc cgatcatgac cgccagcgtc cttacatagg tccctttgga
     4141 gcaagtcact gtaaaccgga agcttgcggt ttctccatga tgtttaatct ctgtcgtcag
     4201 ggcaatgtct tcaatggtta tcatacgttt cggacgttct acttcaatcc ctgctcttgc
     4261 gtattcgtat aattttttgc cgtttacttt tacagcggaa tacatgggcg gaatttgttc
     4321 ttgtttcccc tttaaactgt ttaaaacctt ttctacatcc gctttatcaa tgtcgtgatt
     4381 gacaggcttt gtttccaccg tttctccggt ttgatcctct gttgtggttg aaaagccaag
     4441 cgttatttct gcatcatacg ttttagattt ttcagttaag tattcgacta tttttgtcgc
     4501 tcttcctaca caaatcggaa gcacgcctga cacttccgga tcgagcgttc ctgtatgtcc
     4561 tacttttttt gtttttaaca gctttcggat cttcatgaca cagtcgtgcg atgtcatgcc
     4621 aacaggttta tgtaaaagga gaactccgtt aaccatttgc ttttcactcc ttcttttgag
     4681 cttttttctt ttaaacgaag aaagaggaca gacgatatac gcctatcctc tcatttttta
     4741 ttcagatggt ttctctgaat gtaattcgtg aatcagtgtt tcgatccgat tcccgtaatc
     4801 gattgattca tcgaactcaa attcaatttc aggcgttttt cgaagtctga tgcggctgcc
     4861 gatttcggat cggataaatc ctttcgcttt tgccagccct ttcagcgctt cttcccgttt
     4921 tttctcgtca ccgagaaccg agatatacac ctttgcaatt tgcaaatcac ctgatacacg
     4981 tacatccgtt actgtcagaa aaccaattct cgggtctttc agcttgcggc tgataatatc
     5041 accgagttct tttttcattt gctcgccgac acggtttgct ctcatactca attcaatcac
     5101 ctctaagtta aaaccactct gtcctagtga tcgtccgttc aatttcagga aaagaatcga
     5161 taaacgctag gacgcgctgc agttcttttt ctgtttgaac gcgagaggaa gaaacagcgg
     5221 cgattccgaa gctggttctc tgccaggtgt cctgatagcc aatctccgaa atcgaaacat
     5281 tgaacttgtt ttgaaccctg gttaaaaccc gcttcagaac ggcacgcttt tcttttagcg
     5341 atcctgcatc ataaatgatg cattcacact ccgcaaatcc gatcacgttc tttcaatttc
     5401 ttgcatgaca aacgcttcaa ggatgtcacc ttcacgaatg tcattgtatt tcttaattgt
     5461 aataccacat tcatagcctt gtgaaacttc tttcacatcg tctttaaagc gtttcagaac
     5521 atctacttcg ccttcaaaga tgacgacgcc gtcacgaatt aaacggaggc cgctgtcgcg
     5581 cgtaatggtt ccttcagtaa catatccgcc ggcaattgta ccgattttag atactttgaa
     5641 tgtttggcgt acttctactt gaccaattac tttttcttca tattcaggat caagcatacc
     5701 tttcatggca gcttcaatct cgtcgattac tttgtaaatg atacggtgaa gtcgaatatc
     5761 tacattttca gcttcagccg tactcttagc atttccgtcc ggtctcacat taaacccgat
     5821 aacaattgca ttggaagcag atgccaagat aatgtctgat tcagtaatcg caccaacgcc
     5881 tgtatggatg attttcactt taacgccttc tacttcaatt ttttgaagtg cagccgttaa
     5941 agcttcagca gatccttgaa cgtcagcttt tacgatgagg ttgatgtctt ttacatcacc
     6001 ttgcttaatt tgctcgaata aatcatcaag actgagcttc gctttatcgc tacgctgctc
     6061 ttcaagctgt ttcgaagcac gggcttcacc gacagaacga gctgtttttt catccttaaa
     6121 gacaaggaat tggtctcccg cttgagggac atcattcaaa ccggtaattt caaccggagt
     6181 tgacgggccg gcagttttca cacggcggcc aatgtcgttg accattgcac ggacacggcc
     6241 aaatgtattg ccgactacga tcggatcacc gacatgcagt gttccagtct gtacgagcaa
     6301 tgtcgcgact gaccctctgc ctttatcgag ttcagcttca ataaccgttc cttttgcctg
     6361 acggttcgga ttcgctttca gttcctctac ctcactgaca agcaaaatca tttcaacgag
     6421 ctcatcaatg ccttttccag ttaaagcgga aagcggcaca aaaatggttt ctccgcccca
     6481 agcttcaggg acaagtccgt attccgtcag ttcttgcatt acacggtcag ggtttgcgga
     6541 ttctttatct attttattca cagcaacgat gattggaacc tctgctgctt ttgcatggtt
     6601 aatcgcttca actgtttgcg gcatgacacc gtcatcggca gctacgacaa gaatcgtaat
     6661 atcagttact tctgcaccgc gtgcacgcat tgttgtaaat gcggcgtggc ccggtgtatc
     6721 caaaaacgtg attttcttgc cgttctcttc aatttgataa gcgccgatat gctgagtgat
     6781 tccgcctgct tctccttcaa caacctttgt tttacggatg ctgtcaagaa gcgttgtttt
     6841 cccatggtca acgtggccca tgattgtcac gacaggagga cgaatttcaa gatcctcttc
     6901 attatcaggc tcttcgtatt tttccagctc tgtttcttca agcacaatga cctcttctgt
     6961 ttcaacacca tattctgatg caatgagttc gattgtgtct ttatcaagct cttggttaat
     7021 ggttgccatt acgccaagaa gcatcagctt tttaatgatt tctgaaggct ctttgccaag
     7081 ctcttcagca agtgcgccaa ctgttaaagt gccagagaat gtaattttct caggaagctc
     7141 ttttttcggc tttacaggct tttgctgatg ttggttttta ttattgttgt tgttgcgttt
     7201 attttttttg ttgttgttat tcttcttgtt tttgttaaat tgattattct gcacgtcatt
     7261 cttctttccg tctcgaattt tatttggttg atttccagct gattgctgat taaccccttg
     7321 tggctgtttg tttttgttcg tttctgctgg cttttgagat ttagcagctg cgccgccttt
     7381 tttatatttg gcatcaagct ttttaatggc cttttcttca agcatggcca tgtgattatt
     7441 cacttctaaa tccatgttct tcagtgcggt caaaatttcc ttacttgaaa catttaacgc
     7501 ttttgcatat tcgtatactc tcattttagc cattcgttca cccccaaaaa tattaatcga
     7561 gcaagctgat cagcttattc gcaaaacctt ggtcagtgac ggcgacaacg acacgggctt
     7621 ctttaccgat agagcgtcca agaaccgcgc gactctcgac ttttttataa gggactttat
     7681 aataattgca cttgtcagtt actttttttg ctgtgttaga tgatgcatcc tctgtaagca
     7741 ggacaagctt tgcacgcgca ttcctgattt cttttattac caagtcttcg cctgacacga
     7801 ccttacgagc tcgattggcc agacccagca agggaaacca ttccattcca gacattttat
     7861 tttttcacct tttccgccag ttccagcaat tcatcgaaaa tctggtcatc gatttgtgat
     7921 tgaaattgat tttgcaaagt gtttttcttt tttgctgcta agatgcactc tttatccagc
     7981 gttaaataag caccccgccc attctttttt ccggtcgggt ctactgagat ttcgccttct
     8041 tttgaccgta caactcggat cagttccttt ttaggcttca tttcaccagt cactacacat
     8101 ttgcgtaatg ggatcttttt gtgtttattc acctaaagtc acctcttatt catccgattc
     8161 agcagtttca ggctccgtaa agagcggctc atcatcttct tcaagttctc tcggatagat
     8221 tccaagttct cttgcgtccg tttcgctctt aatatcaatc ttccagcctg tcagtttagc
     8281 agctaagcgt gcgttttgtc ctcttttgcc aattgccaga gacagctggt aatcaggaac
     8341 aataacagtt gtcgcttttt cttcttcatt aacaatgaca tcaagcactt tggaagggct
     8401 gagcgcattc gcgacaaatt ctacaggatc actggaccag ttgacaatgt caattttttc
     8461 accttttaat tcattgacga ttgcttgcac acgctggcct ttaggcccta cgcatgaacc
     8521 gacaggatca acgtcaggat catctgtgcg aacagaaatt tttgaacggt cgccggcttc
     8581 tctggcaaca gattttagct cgacagttcc atcataaatt tcaggcactt caatttcaaa
     8641 caaacgcttt aacaggcctg gatgtgttct tgacacataa atctgcgggc ccttcgttgt
     8701 tttttctact tttgtgatat ataccttaat gcggtcatgg ggcttgtagc tttcattcgg
     8761 catttgctca ttaaccggca gcaaggcttc tattttgcct aaagacacgt agataaattt
     8821 attgtccaga cgctggacga tccctgtcat gatgtcttct tcacggtcga taaattcaga
     8881 atagatcacg ccgcgctcag cttcgcgcac acgctgtgtg acgacctgct tcgctgtttg
     8941 agcagctatg cgcccgaaat ccttaggtgt aacttcgatt tcgacgacat cgccgaccat
     9001 atattccgga tggattccct gtgcctcttc aattgagatc tctaatcttt ggtcgtatac
     9061 ttcgtcaacg acatcttttc ttgcaaatac acggatggag ccagtttcac ggtttagatc
     9121 cacccgtaca ttttgcgctt gattaaaatt ccgcttataa gcagaaatta acgcagcttc
     9181 gattgcttcg atgataattt ctttactgat gcctttttct ttttcaagaa tcgtgagagc
     9241 atctaataat tcactgctca tttaacggtc tcccccctta aaacatttgt attcattaga
     9301 atgtaacagc taatcttgca ttagctatct tttcatacgg aatattgatc cgtttctttc
     9361 ttgttttgat cgtgatctca actgtcactg tttgtccatc aaattcagcc agttcacctt
     9421 caaacacttt tacgccgtca ataggctcat acgtcttaat gtatacgttt tttcctagtg
     9481 atttttcgaa atcggctttt ttctttagcg gacgctcagc tcctggagat gagacttcaa
     9541 gaaagtaatt ttggctgatt gggtctgcct catcaagctt ttcgcttaaa gcttcgctta
     9601 ctttggcaca ttcctcaata tccacaccgt catcggaatc aataaacacg cgaaggaacc
     9661 agctttggcc ctctttgaca aattcaatgt caacgagttc cagctgaagg ctgtctacga
     9721 ttggctgagc catttcttga acggtgtcag tcactttttt gctcatgttc ttcctccttg
     9781 tgctgtcgat ctcatattcg tctcgtcact ctgcataaaa accctgcttc aaaagagcag
     9841 gggctaaaaa gtaaacgatg aacatgtcga gacaaaattc tcctgttcaa tacaaaagag
     9901 cgggtttccc cactctttgc ctcggtaatc gttagcattt ccaataaaac tataccataa
     9961 ccatattttt attgcaaaat cttttcgtta aaaataacct ttaattaagc agtaaaattg
    10021 attcccaacg tgtatacgtc atttggtttc taaatgcaag taaagtcagt aatactcctg
    10081 ttactccatt caaaatacct aactcgtcac taacaatctc cttattcaaa ttatcccttt
    10141 cgatattttg aaatccaaga acattattat cattataata accaagaagt tttttcacta
    10201 aatatatttg ataagattta aatttaggat ccctgattga ttcattaaat aagaatgtaa
    10261 tcgtcaataa tccacttaat ccatgacaaa atgtaggaga atagtttttt tgctgttcaa
    10321 aattcctttt tataacatct ttaaatactg taaccgcaca gttactatat ttcgcgtcac
    10381 ctgttgcttc ctttgctaat agcaatgccc tgcatgttcc tggagaacca taacaccatg
    10441 cgtctcgtgt agttatatca actgtttgat ctttattttt ttcattaaga atgataccgt
    10501 tgggaaataa ataaccatta gcgctcttag tttttgtttt tataaggaaa ttagaaattt
    10561 tctttatcgc atctaattgg ccctcaacaa ttatattatt aatgtaacta agagaaagta
    10621 agctaagcgg tccacttacc ccatgtgcca acccacagtc taatacatat ttttcatctg
    10681 ctaatgaatt tacattttta ttagccatac gagtaattaa tactaatatt ttttctaata
    10741 aatctcttga ctctctctga tccctgaaga acaataagta tcttcctatt ccagcaaaac
    10801 cataaattgt ttcatacaag aataaatcat ttttttgtag gctcgacaag tctttaaatt
    10861 cttcaatatg ttttttaatt atatcgaagt agtataaatt aaaatcagtt agaaaattac
    10921 ggtatctatt tccatttttc gacaaagcta atatacaaaa acctatccct cccatgcctc
    10981 ctagacatga cggtgaataa tcttccattc cttctaattt tttttttata tgaattagat
    11041 attcatgtcc tatcctatcc caacctctat ttggaaaagt ataatctaat tcagcaaaca
    11101 aaatacatac tgatgaaatt ccacttgcaa ctgatatatc atctaatctt tgcaaattta
    11161 agactagttg taaatcagaa atttgtttac tggtcttaat tattatttta tcgatataat
    11221 tgttaagcat gataatacag ctcctagata actataatat gtctcaatta tcagatccat
    11281 cgacttatta cttttaaata ttctactcag atcataggcc tgaataaaat actttttttt
    11341 gttgattata cagatcataa tacatacctt tattctgcaa caattcttta tgagtgccac
    11401 actctattat ttctccatta ttcattacta aaatacgaga tgccagttgc actgtgttaa
    11461 atctatgagt aataaataat ccaattttat tttttaaaaa ctcattatat tttataaata
    11521 attcttgttc agagtaaatg tctaaggcag agcttggttc atccatcata tacaaacttg
    11581 ccttcttaaa gatcgcacgc gatatagcca ttttttgcca ctctccaccg gaaagttgat
    11641 gtcctttatt aaacatcttc cccaactgac tgtcaaatct gtctggatac ttatttataa
    11701 tcttatttgc accagaaatg taagctgcat attccaaaaa atcttgattc ttcatttcat
    11761 tataattacc aaaccctata ttttccctta ttgaaaattc atatttaata aaatcctgaa
    11821 aaataatgct tgtctgagcc ctaatactct caattgagta tttttcaata ggtatagagt
    11881 taattaatat ttctccttca aaaccatcat acaagcgaca tataagtttg attaaggtag
    11941 acttacctga gccattacca ccaacaattg caattgtttc tccttttttt aattcaaaac
    12001 taattttttt aagggcataa ttatttttat ttggatattt aaatgaaaca ttattaaaag
    12061 taattttatt tatttcggta agttggattt tttcctccaa tttagtatca ttattcaatt
    12121 ttctattttt cacaaattca aagaaatcat ttacatacaa attgttttca taaacagaga
    12181 atactccctg cattaacgtt ttcaaagctg tctgagaaga tataaccccc tgtattaagg
    12241 ccatcattgt tccaatcata atttctttgg agaatacttt taatattata tataacatta
    12301 ttccaccaac aattaattgg tttacagttt caaaaattgt cgaaaccttc atttttcttt
    12361 gtgccatttc tttatctgtt tttaaaaaaa ccttgttaat tttttcgtat ctactaatta
    12421 ataaatcgct taaattaaaa agctttattt ccttaatatt aaaatcacgt gtcatcaaaa
    12481 aaatataata gtatattttt cttcttaatg gagttctttc ccattctatt tcgtattcct
    12541 ttttccctaa tttcacaaag aaaattgaag atatgattgg cgttaaaaac aagagtatta
    12601 caacccacca tttccaaata attataatta ttgaagttga aattatagtt ataatattag
    12661 ttaatatatt aagaatctca gtgaaaattt ggaatggtct gtaactagat tctgaagtta
    12721 ctctttgtat ctgatcataa atatgagggt tttcgaaatc aggtaattct aaaatcttag
    12781 ttttctttaa aatttccaag ttaataaaat aggctaactt atttgcaaag atctcctctt
    12841 tatattgttt atattgatta acgataacct gcactaaata aaccactatt aataatatga
    12901 aaataagtaa tactttattt atttgtgttt ctctttgtaa attatttaaa agcgattgat
    12961 ttagaagtaa taaagaaggt ggaataaatc cacttataac agcaattata atgatttgaa
    13021 agaaacttat tttatctacc ttaagaaaaa tcttatataa ttttggccaa ttattaaaag
    13081 aactaattac ttctttataa gtaacattat aaaatttact catagtattc ccttttggta
    13141 tttaagattt ttaagtgtat attttacaag cagcataata tttttctctt tttccctatc
    13201 cactcctaat aatctattta aatgcatatg aattatactc aaccaaatat ctttagtagg
    13261 actatataaa taattgcttt taacagaaaa ttcttcgctg gcatgattaa ttattttttt
    13321 tcttttttcg aaaatactaa ttaatttatt tccatcttcg ctttttctta ggttactcca
    13381 atttagattt gagttacata ggaaaactaa atagtctttc tttaatctaa attccttagg
    13441 aaatttatta ttctctaaaa ttctttcaaa aagattaagt tgttgattat aatcaaaacc
    13501 tatttcttct aagtagaaaa tgacactaag aactgcaatt gtctctttat caaataactc
    13561 attagtagta tacgataaaa aattgaatag ctcagagaca cagatgctat cataataaaa
    13621 taaagtctca caaatatcta taaaatcagg tcctccatat cgttcaattt ctctttcata
    13681 gcaagataat tcgattttat taattaaacc tccttcaatt agatttgatg tccagtcttt
    13741 catttttatt aatacagtcg acaaaagaat gttggggtct ccctgtattc gtaatcttat
    13801 atgcggttta tcatctaaat aacgcacata aaaatattta ttaattaatt gattattatt
    13861 aattaattga tttaaaaaag acggaatatg gtcagcaatt atttcttcat ctctaaatga
    13921 attaaagtac aatttgaaat acaaccaatc actgcctatt tgtttttttg taagaatact
    13981 attagtataa ataatgggtt tattcttttt agttttgcct atactattat tatttttatt
    14041 ttgtatgaga ggaaaaataa actctatgtt atatttattt ttattcctat cttgtgccca
    14101 tgactttgac aaattaattt cactttcgat taatctaata atcttcattt tttggatttt
    14161 tttatacagt attttcaagt gaagatgaac gtctagattt aaaaataatt tttcatcacc
    14221 ttcaactaaa tatacacttt taggaatact ccattttttt gcccatcttt taaaaatttt
    14281 taaccattca tcataattag gtttttccgt aatatgatca cttaaattaa aattccacat
    14341 tgcaggggat aatattgttt ttttgaattt aactcttggt aaaaattcac tttctattag
    14401 tcttccccaa ttaaatcctg taagatattg atcattaaat aatgaagctt cttgtataaa
    14461 tctaaataca tttggagtta tatccatatt aactagacta tttacgctaa tattaattct
    14521 cttatttaag tttttggatt taaaataaaa taaatcctct tctacgccga caactatatc
    14581 ctcaattgga atagtttcat tttcctcaga acaaaagttg ttaaggttaa tttcatagtc
    14641 ggaaaaatta tctaccatca taatattggc tattttacca ttattagggg tgtaactcat
    14701 ttcggcatta atataatgct cacaaattgt ttgttggtca tagaattgtt ttacattagt
    14761 tttatctttt aaaagatcag taaatctacc cgcggctttt cctgcaaagt tagaaactgg
    14821 gttttcagag ttaaggaata ttgtatactt tcctttatta aaggaatcaa tattatcagc
    14881 tacaatattt ccgaatattt caaacgattt aacgaaatta ttttggccac ttatattttt
    14941 ttctttattt aaatgtttta gttcttccaa tgtaatttca atttcttgct cattttcttt
    15001 tatagaatta agtaactttc ttaacaaata gttttccaac ttttgattac tcttatagat
    15061 aaactctcta gtactcgtag gatttttata acttgctgga gatcctaatc cgatatcatt
    15121 atttaataat tctaataatt caacctcgcg atgctctcca tacttatcta taaattcatt
    15181 tagatagttt tttagatgtc gaggtttatt atttgttata gaaaagtact ctaaacactc
    15241 tgtcagttct attaaatctt tttttacatt attacttaat ttaatctcac ttttattatt
    15301 taaactcaaa ttaacttgta agtaaatatc gctaacaaca agattgctca ttagtttttc
    15361 gatctcgttg acttcattta agccttctcc aattggcaag gtttcataat aatttatttt
    15421 agcttgtatt gataataact cctgaaggat atattgtaaa tcttgttttt caatactttt
    15481 aattttattg atcacataat taaacggcga tttctccaac agagatggtc ttaagtctgt
    15541 aattaagtaa tcttgatcta ctaaattgtg tattaaagat aatattttct cgctagttac
    15601 tgaggaatac tcttttttta aataccttaa tatatttttt attttaagag gttcttgtgt
    15661 taacttctct ataatttcaa taggaggact aacaatgatt gagcttatgt catttgttat
    15721 gttattttga cgtgcagaat caatttttga attataggaa agaaaataac ggttccctac
    15781 tttctcaact aagttgttga attttacatt aagctctaaa aaaatcgaat tttctttttc
    15841 taattttttt atcaacttat ataaccaatt catatctggg ttgcacttct taatattatg
    15901 tacaagagga tctatattaa ttgaggtttc attctcgaat cttccaacag taacactgga
    15961 gaaaagccca aaaggagttg ttctagaggt catccgcaat aaataattat ttaatgatat
    16021 tgctatttgc tctttccttt ttttgtccgt tatatttttc caatatttta aattctcata
    16081 taatgaagga ctggcaatat aaatagcttc cataaaaatt ggattattaa ttaaatcttt
    16141 cacccagtta gagtaacttt cttttccatt tatcatttta tgtaaataat tttcaagaaa
    16201 ggttagagat aaagtaggag ttctaataaa gaaactatct aaagagaacc atttctgctc
    16261 tatattcttt aaactatctt tctttagtga tttcatataa acaacactct ctttataaca
    16321 aatttaatta aacaacttac caaagaggtg aagataatac tatcttcacc caaaatatta
    16381 agcatcacaa tacccatagt ttttagtaat aacgatacca tcacacattg cccgagaaca
    16441 gagagctttt gaagcgacac caccactgca accaaaggta agtcgaatac tattaggttc
    16501 tacattcgat ttgctcgttt gaattttcaa atctaaatca aaaatatcct tttccaaacc
    16561 aatcacctcc cttttaatag aaatgtaaca tatattttgt ttatatgtca atattatact
    16621 ttaacattcg acttaattgt ttatatttta attattttca aaacagaaaa agacacaatt
    16681 aagaaaactg tgtctttttt attttaaaac agtgacaatt gattttgatc aggcagtgac
    16741 tccagacagc catggcgatc taagtactct aaaatcgttt ttgatacttt ccctctcttt
    16801 tgcaaatctt cttttgagag gaattcgcct tcttcgcgag cttttacaat gttcaaagca
    16861 gcgttcgtcc ctaaccctgg aatagagtta aacggcggaa taagactgtt gccgtcaata
    16921 ataaactctg tagcgctgga gcgatataaa tcgacttttt ggaatgaata gcctctctca
    16981 cacatctcaa gcgctaattc taaaacagtc agaaggttct tttccttcgg tgaagcatcg
    17041 agtcctttag cgtttatatc ctccattacc gctctgattg ctgtagagcc cttgatcatt
    17101 gtatcaatat caaagtcatc tgcacgaacg gtaaaataag ccgcataata caaaagagca
    17161 tgatgcactt taaagtaagc aatgcggact gccattaaga catatgccgc ggcgtgggct
    17221 ttcgggaaca tgtatttaat ctttttacaa gaatcaatat accagtctgg gacattgtta
    17281 tttttcattt cttcttccca ttcaggcgtt aatccttttc ctttacgcac gaattccatg
    17341 attttaaagg caagggacgg ttcaaggcct tgatagatta aataaaccat aatgtcatca
    17401 cggcagccga taacctcact cagctcacaa atattattgt ggatgagctc ctgtgcattg
    17461 ccaagccata catcagttcc gtgagacaag cctgaaatct gaacgagctc agaaaaagtg
    17521 gtcggctttg tatcttcaag catctgccgg acaaatcggg ttccgaattc aggaattcca
    17581 agagtgcccg ttttacagcc aatctgttct tcagtcacac cgagtgattc ggttccctgg
    17641 aagatcttca tcacttcagg atcatccgtc ggaattgttt tcggatctat tccgcttaag
    17701 tcttgaagca tccgaataac agtcgggtca tcgtgtccga gaatatcaag ttttaacagg
    17761 ttgtcatgga tggagtggaa atcaaaatga gtcgttttcc actctgaacc tgtggcatct
    17821 gccgggaact ggatcggtga aaaatcataa atatccatat aatccggaac tacgataata
    17881 ccgccagggt gttgtccagt tgtacgtttt acacctgtgc atccctgtac gagccgatct
    17941 atttcggcac cgcgcatatg aagattgttg tctccggcat agccttttac ataaccgtag
    18001 gctgtttttt ctgccaccgt gcctattgtt cccgcacgat atacattgtc ttctccgaac
    18061 aatacttttg tgtaattgtg tgcttgcggc tgatattccc ctgagaagtt caaatcgata
    18121 tcaggtactt tgtccccttt aaatcctaag aacgtttcaa atggaatatc atggccgtct
    18181 tttttcaaag gcgttccgca atgagggcat gtcttgtcag gcaggtcaaa accggaaccg
    18241 acagaaccgt cattaaagaa ctcagaatgc tggcactcag gacaaacata gtgcggcggc
    18301 agcgggttta cctcagtaat ctcagtaagt gtcgcaacta atgaagatcc tacggaacca
    18361 cgggaaccaa cgagataccc gtcatctagt gaacgtttta caagtttgtg agagatcaag
    18421 taaataacag caaatccgtg gccaataata ctctttaact ctttttcaat ccgcgcttcg
    18481 acaatttcag gcagctcttc cccgtaaatg cttcttgcac gctgatagct catttctctg
    18541 atctcttcat cagcgccttc gattttcggc gtatataaat catctttaat cggcttgatg
    18601 tcatcaacta aagaagcaac cttttgggta ttggtgacta cgatctcctt cgcttttttt
    18661 tcacctaaga aagaaaaagc ttcaagcatt tcgtctgtcg ttctgaaatg cactttcggc
    18721 agttcatgcc tattcagcgg atttgccccg ccttgtgagg atattaaaat ctttctgtag
    18781 attttatcct catcattcaa gtaatgaaca tttcccgtag caacaaccgg tttattaagc
    18841 ttttccccca gcttcgtgat attcgcaata atttctttca gcgctttttc atcacggacc
    18901 agttcaagct ccagcaagtg acgatacact tcaggcggct gaacctcaag gtaatcatag
    18961 aatgacgcga tatcttccac ctcttcaggc gatttttgca tcattccctc aaaaacctct
    19021 cccctgtcac aggcagaacc gatcagcagc ccttccctgt atttctcaag ctgagatctc
    19081 ggaatacgcg gcactctgta aaaataatga atatgagaaa gtgacacaag cttaaataaa
    19141 tttttaagtc ccgtgctgtt cacggcaagt aatgttgcat gatacggtct tgatctttga
    19201 taagcattgg actgacccat attttcattc aactcatcat ggtactgaat acctttttca
    19261 gccgcgtctt tcagcatttt cagaagcaaa taagcggttg cctcagtatc atagatcgca
    19321 cggtgatgct gtgtgagttc gatatcaaac tttttacaaa gtgtgttcag ccggtggttc
    19381 ttaaattccg gatagagaaa acgtcctagt tctagcgtgt caatgactgg gtttttagct
    19441 ttatcgactt caagaagctt tttataggct acatttaaga atcccatatc aaagcttgca
    19501 ttatgagcga caaggatatc atcgccaatc cattctctga aatctcttat tacatctacg
    19561 acatccggag cgtcttgtag catatcatca gtgatccctg tcagctctat gattgtggcg
    19621 gaaagcggac gatgcgggtt cgcaaacgcc tcaaatttat caataatttc tccgcctttt
    19681 acttttactg cagccagctc aataatggta tcgtatacag cagacaatcc tgtcgtctca
    19741 acgtcaaaaa caacatatgt ttcttcttcg agcagacgat gtgcggcatt ataagcaatt
    19801 ggcacgccat catccacgag attcgcttcc atcccgtaaa tcattttaat tccatgcttt
    19861 ttggccgcag aatacgcatc agggaaggat tgaacgacag catggtcagt caaagcgatg
    19921 gcctcatgcc cccatttttt cgcctgttcg acaagctttc caatacccgt aacagcatcc
    19981 atttggctca ttggggaatg aagatgcaat tccactcttt tttctccttc aggtgctgaa
    20041 tcttcacggg tttttgcttt tatttcgttt acgtcatttg cgatcatgac aaggtctctg
    20101 acaaatgtat cattttgaat gcttccgcgt gcttttaccc acattccttt tttcagagac
    20161 ttcatcagtg ccgcatcttc tttttcacgt gcaaacattt tgatcaaaat actatttgta
    20221 tagtctgtaa ttttgaagat acacagcgtg cgcccgctct tcagctcgcg cgtctccaca
    20281 tcaaacacat aaccttggac cgtaattctc cgttcttcgt ccatgatgct gtcaagtgtc
    20341 cgaatttcct cgttatcttt aatttgataa ccgataacaa gaggaccaga tggtgcttgg
    20401 tcttcatcac tttctttatc tttcttctcc atttcaatca aggcctgcat agcccgctct
    20461 tggtcttctg caagcttttg ctcccgaaac ttttgaactt cctgctcgga tacaaatatt
    20521 tcagcatcaa gctgaagatc tggaaagcca aattgacggt agcctgcttg tatcatggaa
    20581 ctgtatttgt tctttagcgc agccgcttct gtatccgttt tggttttgac aatcagttta
    20641 ttgcccttca gcttcggttt ttgctggttt aaaagactga tgatcggcgg cgaaatgccc
    20701 tgcagttctt caatgcagcg tgaccagtag tcttgaacga tactttcact gacctcggca
    20761 tcctgaactt caattgaaga tgtcactttt gctatgtggg caaacgattg cgtcagcctc
    20821 gttgttaatg tgtcatatat ttgaaaaggc agcaaagatt taaattgaaa atgaaaatgc
    20881 caagatttag aagctttgtg aattgtcagc tttttaatct cgccatgttc aaagtatgtc
    20941 atgaaggtat catctgtcat attaatctgc tgcagaagaa tttgaaactg ccttctgttt
    21001 actgataact gttccattaa gacagtatcc ctccctaaaa acatcataag tgaaggtacc
    21061 tcaggcaatg aggtaccttc tattatttct attttaacat gttttttgat aaatcgttat
    21121 ggtgattact gcttgctgat aaacgcagat aattcgtcta ctgaaatctc agttgactca
    21181 ccagtttgac gaattttcac ttcgacgatt ccttcgtcag cccgttttcc gacagtgatg
    21241 cggattggaa ggccgattag atctgaatca gcgaatttta caccggcacg ctcagcacgg
    21301 tcgtcataga gcacttcata gccttccgct tttaaatcgg catacagctt ttcagcaagc
    21361 tctctttgcc catcgttttt catgttcaat gcaagaatat gaagatcgta cggggcaacg
    21421 ctttttggcc atattaatcc tttttcgtcg tgatgctgtt cagcaatagc agaaagcgtt
    21481 cttgacacac cgattccgta acagcccatc agcattggct gcgcgcgtcc gttttcatct
    21541 aaatatgtcg cattcatcgc ttctgaatag cgtgttccga gcttaaagac ttgtccgact
    21601 tcgattccct cagcaaaacg gatcgttccc ttgccgtctg gtgaaggatc accttcttta
    21661 ataaaacgaa gatcagcaaa ttctttaatt tgcgcgtcac gattcacatt gacattttta
    21721 taatgatgat ctccttcatt tgccccggca acagcattaa ccattgcttt cacagcttga
    21781 tcggcatata cttccacatc ctgatgaata ccaacagggc ctacaaaacc tggctctgtt
    21841 ccgagctgct gaatgacctc ttcatgtgta gcaagctcta caacttctgc atgaagcaag
    21901 tttttcactt taatatcgtt aacttcatga tcccctctta caagcactaa gacaaaacgg
    21961 tcatcagctt taaacaatac tgacttaatg cacgcttcag ccgaaacctg taagaacgca
    22021 gtcagttctt cgattgtttt cacgttaggc gtatgaacct tctctagagc tttaggctct
    22081 tcatctgaag gaacttcctg gtgaagaact tcagccatct cgatattagc cgcgtactgt
    22141 gattcatcag aatacgcaat cgtatcctct ccgatcgcag aaagtgccat aaattcgtgc
    22201 gtatcctttc ctcccattgc gcctgaatca gcgataacag gtcttacatt aatgccgcag
    22261 cgggcaaaaa tattagaata ggcctcgtac attttttgat acgtttcatc caggctctct
    22321 gcagatgcat ggaaagagta cgcatccttc ataataaatt cgcggcctct taacaaaccg
    22381 aagcgaggac gtttttcatc tctgaactta gactgaattt gataaagagt cagagggaga
    22441 cgcttataag atttaacctc atcgcgaaca agcgaagtga taacctcttc atgcgttgcc
    22501 cctaaagcaa attcacggcc atgacggtct tttagtctca tcagttcggg accatacgta
    22561 taccatctgc ctgattcctg ccatgtctct gcctgctgca acgcaggcat gagcatttct
    22621 acggcatcaa ttttctccat ttcttctcga acaatctgct gaatgttttg aatcacctta
    22681 tacgcaagag gcatatagct gtataccccg ctcgtattct gtctgataaa tcctgctctc
    22741 agaagaagct gatgactttt tgcttcggca tcagctggaa cttcacggag cgtaggaata
    22801 agcgtcaagc tttgtctcat ttcttcgcac ctctgattga tttacttttc gtttacaaaa
    22861 acagccgctg gatatcgttc catgtgacaa ccagcataag aagcattaag aaagctactc
    22921 cgataaacac aacaaatgct tctttttccc tgttaatcgg tttgccccga atcgcttcaa
    22981 taaatagaaa caacagtctt cctccgtcaa gtgccggaat cggaagcagg ttgacaatcc
    23041 caagattaat gcttaaaaac gcagcgaaac gaaccaaatt aactaacccg gttttcgcca
    23101 cttggtctgt catatcataa ataccaactg gtcccgccaa catatttatt ttaaattgtc
    23161 ctgttactaa attaccaaac gtttctaaga tttgattgcc aatgtcaact gttgatgtcg
    23221 cgccgtaagc aaccgctgag agtacgcctt tttcagtcgg cgcataggaa ccgaaacggc
    23281 cgattgtttt tttgttctca tctttaacag cttccggagt caccgaaata tgaagcgttt
    23341 tgttatctct ttttaccgca acgtccattt ctttctccgg gttttctttt acagcggaga
    23401 caatgtcagt ccaagacctc attttctctc cgttaatgct ttggatataa tccccttctt
    23461 ttagccctgc ttcagcagcc cgtccattgt ctgtcagctg cccgagcata ggttcatttg
    23521 acggtacgcc ttgaatcagc ccaagcatca ctaaaatgac gtaagctaaa ataaagttca
    23581 taatcggccc tgcagcaatt gctttaatcc gctgccacac aggtttggaa ccaaattggc
    23641 gattatacgg cgcaatctgc acttcttctc cgtctacaat aaaaaaggat gtttcgctga
    23701 cagtaaagct ggaaagttcg tcctctttcc cctgttcata accggtgatc ttcatgtcat
    23761 gctctagatc cgctgtttcc acttcaatga ctaaagcatc cggatatttt tccttttgat
    23821 tgatgatgac tttctcaact tgatcttctt tattaaacag aagcccgacc gtgtatccgg
    23881 gtttcacctc aatcatttcc ggatcttcgc cggccatacg aacaaatccg ccgaccggaa
    23941 gcagcctgat cgtataaact gtttcatttt ttttgaaaga aaaaatcttt ggaccgaagc
    24001 cgatcgcaaa ttcacggcag agaattcccg ctctttgggc tagcaataaa tggcccagtt
    24061 catggaagaa aacgagcgtt ccgaaaataa tgataaacgc tataactgta ttcacgaaca
    24121 taccacctta tgtgagtatt gaattgacgt atccccgggt atctttgtcc acttcttgaa
    24181 tgtccgccag gctcggtttt ttcagtaatt gatggcgggt tagtgccttt tcgatacagt
    24241 cttcaatagc caaaaacggt atcttgccag ctaaaaaggc agcgacagct acttcgtttg
    24301 ccgcatttag cactgtcggc attgttcctc ctattttacc tgattcaaaa gcaaattgta
    24361 agcatcggaa cctgtcaaaa tcagctttct caaaatgaag gctgccgatt tcccataatt
    24421 caagcctttt cgcatctggt aatggcaatc ggtcaggata agtgagcgca tattgaatgg
    24481 ggactctcat atccggagtt ccgagctgtg cgatcacact tttatcatgg aactcaacca
    24541 ttgaatggat gatgctctcc ttatgtaaaa ccacatcaat ttgttcataa ggtatatcga
    24601 aaagccagtg tgcctcgatc acctctaatc ccttattcat cattgtagcc gaatcaattg
    24661 taatttttgc acccattgac cagtttggat gttttaatgc atcttcaacc gttactgatt
    24721 cgagctcctc ccgcgtcttg tcccgaaaac ttccgccgga tgccgtaatg atgaggcgtt
    24781 caatgttttt agcctgttcg ccttgaagag cttgaaaaat ggctgaatgc tcactgtcaa
    24841 caggcagcag cggaacatca tatttcttag catgttcttt tactatatgc cctgcagtga
    24901 caagagtttc cttatttgca agcgcaattg tttttttctg ttcaattgcc tttaacgtcg
    24961 ggataagacc gacgcttcca agcaaagcgt tgacaacaat gtcaacctcc tccatcactg
    25021 ctgcttctat cagtccttct tctcccagcc cgatttggca ttcaaaagaa aaagacattt
    25081 gttttaattt atgatatgta tccagatcac cgacagagac aaacttcggc tgaaagacct
    25141 caatcattgg aacggcctta tcaatatttc tgccaaacga catagatacc agctgaaatt
    25201 gatcttgatg tgcacgcagt acatcaagag tctgttcgcc gattgatcct gttgctccta
    25261 aaagacaaat atttttcaaa gttgccacta ctcctattct tattgctgca tgatcagtct
    25321 catattcata ttagactttt ttatgaaaaa agggcaagca gaaagtacaa gaaaggcatg
    25381 acaaacaaga aactgtcaaa acggtctaat ataccgccat gcccaggaag aatattccca
    25441 gaatccttta catcgtaatg tcttttcaag gcggattcca ctaaatctcc aagttgtccg
    25501 aaaacagaca aaaacagcgt gatcaacagc agatagatat acgggatcgg aagttgtgca
    25561 acaagctgaa aaatcgtcgc caatacaagt gcgatgacaa ttccgcctgc aaacccttcc
    25621 actgttttat tcggactgat ttcaggccac agtttccgct tcccaagcga tttaccgaca
    25681 aaataggcac cggaatcggt ggaccaaatg acaacacacg cataaaaaat gtatgttaat
    25741 ccgtattggt caagatttct gatttcgata aaataatgaa aacacattcc gatgtaaatt
    25801 gctgcaagcg taataaaccc gacttcatca aaagtaaagg tgttcttgac caacactgtg
    25861 taagtcagca atagcagtac cgcaaataaa gcgatttcca ttttggaaat tccgtccgct
    25921 tcaaaaaacg aatactggct tggcaataag aacatccaca ataataaaag accgatcaaa
    25981 cccggcagtg aaaccagctt cagctttttc atccgtaaaa gttcaaaaag cgccacactg
    26041 cccatagcat aaattaatat ggtgaacggc aatttcccga caataaccaa aaataaaaat
    26101 acaattgctg ccagaacacc tgtcaaaatt ctttgtttca tgtccaccat cctctaaatt
    26161 ccgccaaacc tccggcctct ctgctgaaac tctcctaacg cctgcaagaa gtgatcttct
    26221 ttaaagtcag gccacaagac gtcagtaaag acaaattcac tgtaggcaac ctgccatagc
    26281 ataaaattac tcagcc
//
