LOCUS       NZ_CP028201            21612 bp    DNA     circular CON 22-JUN-2024
DEFINITION  Bacillus subtilis strain SRCM102753 chromosome, complete genome.
ACCESSION   NZ_CP028201
VERSION     NZ_CP028201.1
KEYWORDS    RefSeq.
SOURCE      Bacillus subtilis
  ORGANISM  Bacillus subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 4025706)
  AUTHORS   Jeong,D.-Y.
  TITLE     Bacillus subtilis SRCM102753 having probiotics activity species
            isolated from traditional soybean paste
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4025706)
  AUTHORS   Jeong,D.-Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-MAR-2018) Functionality Evaluation Team, Microbial
            Institute for Fermentation Industry, Minsokmaeul-gil 61-27, sunchang
            56048, Korea, Republic of
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. v3.0
            Expected Final Version            :: yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009913255.1-RS_2024_06_22
            Annotation Date                   :: 06/22/2024 02:37:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,123
            CDSs (total)                      :: 4,002
            Genes (coding)                    :: 3,910
            CDSs (with protein)               :: 3,910
            Genes (RNA)                       :: 121
            rRNAs                             :: 10, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 58 of 92
            Pseudo Genes (incomplete)         :: 42 of 92
            Pseudo Genes (internal stop)      :: 14 of 92
            Pseudo Genes (multiple problems)  :: 19 of 92
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:16:20
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3460827
            Orig. end                         :: 3482439
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP028201.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21612
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="11"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     cand_cluster    1..21612
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21612
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11612](+)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11612
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     misc_feature    complement(87..101)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.21"
                     /tool="antismash"
     gene            complement(179..3865)
                     /gene="narG"
                     /locus_tag="C7M16_RS17500"
                     /old_locus_tag="C7M16_03450"
     CDS             complement(179..3865)
                     /GO_component="GO:0009325 - nitrate reductase complex
                     [Evidence IEA]"
                     /GO_function="GO:0008940 - nitrate reductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009061 - anaerobic respiration [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="narG"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391609.2"
                     /locus_tag="C7M16_RS17500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_03450"
                     /product="nitrate reductase subunit alpha"
                     /protein_id="WP_160221882.1"
                     /transl_table=11
                     /translation="MKKKKMSPLFRRLNYFSPIEHHSNKHSQTTREDRDWENVYRNRWQ
                     YDKVVRSTHGVNCTGSCSWNIYVKNGIVTWEGQNLNYPSTGSDMPDFEPRGCPRGASFS
                     WYIYSPLRVKYPYVRGVLINLWREALQTHQNPLEAWKSIVENPEKAKSYKQARGKGGFV
                     RAEWPEVLKLISASLLYTVMKYGPDRNVGFSPIPAMSMISHASGSRFMSLIGGPMLSFY
                     DWYADLPPASPQIWGDQTDVPESSDWYNSGYIITWGSNVPLTRTPDAHFLAEARYKGAK
                     VISISPDFAESSKFADDWLSIRQGTDGALAMAMGHVILQEFYVNQETERFIEYAKQYTD
                     FPFLVTLSKENGVYTAGRFLHAKDIGRKTKHDQWKPAVWDEQTSSFAIPQGTMGSRWDG
                     QQKWNLHMIDEETGEPIEPRLSVLGIEDEIGTVRIPYFSNDGNKVLERDLPIKKMNLNG
                     EETYITTVFDLILANYGVNRGIGERSAVSYDDPEPFTPAWQEQMTGIKKEAVVKIAREF
                     AQNAIDTDGRSMIIVGAGINHWFNSDTIYRAVLNLVLLVGAQGVNGGGWAHYVGQEKLR
                     PAEGWQTIATAKDWEGVPKLQNGTSFFYFATDQWRYEDQPISDLASPIAASSRYKHHAD
                     YNVLAARLGWLPSYPTFNQNGIDLYKEAEKAGAATPEDVGAYVASQLQEKKLKFAIEDP
                     DNEVNFPRNLFVWRANLISSSGKGHEYFLKHLLGTTNGLMNDDSDSIRPEEIKWREQAP
                     EGKLDLLINLDFRMAGTALYSDIVLPAATWYEKHDLSSTDMHPFIHPFAPAISAPWESK
                     SDWDIFKALSKAVSDLAEEVDMEPVKEVVATPLLHDTMQELAQPFGKINDWSKGECEAI
                     PGKTMPNIQVVERDYKHIFHKMTALGPNVALKPSGTKGMSWSIADEYESLKQRLGEITS
                     DSVAKGCPNISEAKQAAEAILTLSSTSNGKVAVKAWESLENITNLKLKDLAEEREEECF
                     TFEQITAQPKTVITSPAFSGSEKGGRRYSPFTTNVEKLIPWRTLTGRQSYYVDHELMME
                     FGETMATFKPILQHRPFLSKRPDQEGKEIVLNYLTPHNKWSVHSMYFDSLPMLTLFRGG
                     PTVWMNKDDAEDTDIKDNDWIECFNRNGVVVARAVLSHRIPKGMAFMHHAQDRHINVPG
                     TKLTNNRGGTHNSPTRIHVKPTQMIGGYAQLSYGFNYYGPTGNQRDLNVVIRKLKEVDW
                     LED"
     misc_feature    complement(3931..3946)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     misc_feature    complement(3955..3968)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.07"
                     /tool="antismash"
     misc_feature    3955..3969
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.64"
                     /tool="antismash"
     gene            complement(4084..4560)
                     /gene="arfM"
                     /locus_tag="C7M16_RS17505"
                     /old_locus_tag="C7M16_03451"
     CDS             complement(4084..4560)
                     /codon_start=1
                     /gene="arfM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391610.1"
                     /locus_tag="C7M16_RS17505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_03451"
                     /product="Crp/Fnr family transcriptional regulator ArfM"
                     /protein_id="WP_003243032.1"
                     /transl_table=11
                     /translation="MNQCDYLLFLKQLPMFNEVPLSIVETLLKNGTFIRGSCDQSPSFL
                     HSQSVYIVLKGSVRFMDTRLPEGSKTVALWEKGDVFPIDEKGGLYLSPFISVNATSDIL
                     ILNIPYYIFKKMMSYHPQLQMNFLAMLQQNVFCSYQLFLRYLHTSQDENAEPGS"
     misc_feature    complement(4618..4633)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            4704..5423
                     /gene="ywiC"
                     /locus_tag="C7M16_RS17510"
                     /old_locus_tag="C7M16_03452"
     CDS             4704..5423
                     /codon_start=1
                     /gene="ywiC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391611.1"
                     /locus_tag="C7M16_RS17510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_03452"
                     /product="YwiC-like family protein"
                     /protein_id="WP_014481214.1"
                     /transl_table=11
                     /translation="MKALIPKQHGAWAMLLIPFLLGMVKGGPVIWHIPLFLGWLFLYLA
                     VYPVTLALKKKQSKPYQKWMCYYGFPACCFLMISVFHKPPLIWVGVSLLPLFLIHMYFA
                     RRKNERALLNDVAGVLFFCSGGFASCWLGMGTLDGWAWFIFLQSALFFIGSSFYVKSVI
                     RERKNRAFAYWSWGYHLLLPFLSALFGAGWAFLAFIPSSLRAWFFHGRDWPVKTIGILE
                     IVNACFFLAVMCLFITR"
     gene            complement(5455..6171)
                     /gene="fnr"
                     /locus_tag="C7M16_RS17515"
                     /old_locus_tag="C7M16_03453"
     CDS             complement(5455..6171)
                     /codon_start=1
                     /gene="fnr"
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391612.1"
                     /locus_tag="C7M16_RS17515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_03453"
                     /product="fumarate/nitrate reduction transcriptional
                     regulator Fnr"
                     /protein_id="WP_003227573.1"
                     /transl_table=11
                     /translation="MNFLSVRPSDSDLISSDLHELLESISTKRKMEKHTYLFREGMDAE
                     ELYLIQSGLIEIGKLTSDGKDLTLRICQKHDIVGELTLFTEEPRYMLSAKVLEDGEVLV
                     INKNKLEKELIQNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYG
                     VERSDGILINIVLTNQDLAKFCAAARESVNRMLGDLRKKGVISIDESGKIILHKRDYLR
                     CEIECENCPLEICNID"
     gene            complement(6270..7457)
                     /gene="narK"
                     /locus_tag="C7M16_RS17520"
                     /old_locus_tag="C7M16_03454"
     CDS             complement(6270..7457)
                     /codon_start=1
                     /gene="narK"
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391613.2"
                     /locus_tag="C7M16_RS17520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_03454"
                     /product="nitrate transporter NarK"
                     /protein_id="WP_014478287.1"
                     /transl_table=11
                     /translation="MINRQHIQLSLQSLSLVAGFMVWVLISSLISQITLDIHLSKGEIS
                     LVTAIPVILGSLLRIPLGYLTNRFGARLMFMVSFILLLFPVFWISIADSLFDLIAGGFF
                     LGIGGAVFSIGVTSLPKYYPKEKHGVVNGIYGAGNIGTAVTTFAAPVIAQAVGWKSTVQ
                     MYLVLLAVFALLHVLFGDRHEKKVKVSVKTQIKAVYRNHVLWFLSLFYFITFGAFVAFT
                     IYLPNFLVEHFGLNPADAGLRTAGFIAVSTLLRPAGGFLADKMSPLRILMFVFAGLTLS
                     GIILSFSPTIGLYTFGSLTVAVCSGIGNGTVFKLVPFYFSKQAGIANGIVSAMGGLGGF
                     FPPLILASVFQATGQYAIGFMALSEVALASFVLVIWMYWQERMKTHTERNSQSIN"
     misc_feature    complement(7522..7537)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     gene            complement(7593..9263)
                     /gene="argS"
                     /locus_tag="C7M16_RS17525"
                     /old_locus_tag="C7M16_03455"
     CDS             complement(7593..9263)
                     /EC_number="6.1.1.19"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391614.1"
                     /locus_tag="C7M16_RS17525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_03455"
                     /product="arginine--tRNA ligase"
                     /protein_id="WP_003227570.1"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGD
                     YSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELEKLRKDLENFRVPFDVWYSETSLYQNGKIDKALEALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKP
                     AADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     gene            complement(9260..9688)
                     /gene="ywiB"
                     /locus_tag="C7M16_RS17530"
                     /old_locus_tag="C7M16_03456"
     CDS             complement(9260..9688)
                     /codon_start=1
                     /gene="ywiB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391615.1"
                     /locus_tag="C7M16_RS17530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_03456"
                     /product="DUF1934 domain-containing protein"
                     /protein_id="WP_003243604.1"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFVTGASTIAKYKMSFGELELKTSTKSIQ
                     SDLDEEKGRISIAYDMHVGDEQEHLHNMTITYEGGTHA"
     misc_feature    9895..9910
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 25.99"
                     /tool="antismash"
     gene            10001..10132
                     /gene="sboA"
                     /locus_tag="C7M16_RS17535"
                     /old_locus_tag="C7M16_03457"
     CDS             10001..10132
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="sboA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391616.1"
                     /locus_tag="C7M16_RS17535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_03457"
                     /product="subtilosin A"
                     /protein_id="WP_003222002.1"
                     /sec_met_domain="Subtilosin_A (E-value: 8.7e-29, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       10001..10030
                     /prepeptide="leader"
                     /note="peptide class: sactipeptide"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="C7M16_RS17535_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       10031..10132
                     /prepeptide="core"
                     /locus_tag="C7M16_RS17535_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[10000:10030](+)"
     gene            10089..10241
                     /gene="sboX"
                     /locus_tag="C7M16_RS17540"
     CDS             10089..10241
                     /codon_start=1
                     /gene="sboX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_054594.1"
                     /locus_tag="C7M16_RS17540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bacteriocin-like protein SboX"
                     /protein_id="WP_010886632.1"
                     /transl_table=11
                     /translation="MKLPVQQVYSVYGGKDLPKGHSHSTMPFLSKLQFLTKIYLLDIHT
                     QPFFI"
     gene            10266..11612
                     /gene="albA"
                     /locus_tag="C7M16_RS17545"
                     /old_locus_tag="C7M16_03458"
     CDS             10266..11612
                     /codon_start=1
                     /gene="albA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391617.1"
                     /locus_tag="C7M16_RS17545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_03458"
                     /product="subtilosin maturase AlbA"
                     /protein_id="WP_085185524.1"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1079.3, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 4.9e-29,
                     bitscore: 98.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.2e-07, bitscore: 28.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 1.5e-44, bitscore:
                     150.4, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 3.3e-06, bitscore: 24.6,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1e-21, bitscore: 75.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 5e-10, bitscore: 37.5,
                     seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.6e-09, bitscore: 36.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIEQMFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLN
                     KTAYELCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQLGNRASR
                     RTITTSGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIEQFKKTADMLFDN
                     GVLTCEITGGEIFVHPNANEILDYVCKKFKKVAVLTNGTLMRKESLELLKTYKQKIIVG
                     ISLDSVNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIVHPTKDAEQHHKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFNSPLVHKLWQAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     aSDomain        10281..10556
                     /aSDomain="Subtilosin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a subtilosin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_C7M16_RS17545_Subtilosin_rSAM_RRE.1"
                     /evalue="3.40E-31"
                     /identifier="RREFam018.1"
                     /label="C7M16_RS17545"
                     /locus_tag="C7M16_RS17545"
                     /protein_end="97"
                     /protein_start="5"
                     /score="98.4"
                     /tool="antismash"
                     /translation="MFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLNKTAYE
                     LCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQ"
     gene            11625..11786
                     /gene="albB"
                     /locus_tag="C7M16_RS17550"
                     /old_locus_tag="C7M16_03459"
     CDS             11625..11786
                     /codon_start=1
                     /gene="albB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391618.1"
                     /locus_tag="C7M16_RS17550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_03459"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbB"
                     /protein_id="WP_003222006.1"
                     /transl_table=11
                     /translation="MSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGM
                     RARKADSR"
     gene            11783..12502
                     /gene="albC"
                     /locus_tag="C7M16_RS17555"
                     /old_locus_tag="C7M16_03460"
     CDS             11783..12502
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="albC"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391619.1"
                     /locus_tag="C7M16_RS17555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_03460"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_003227564.1"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQLKTHRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFASLAEAFHFSKYINRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYQKMREYCEAGGTILFSSHLLDVVQRFCDYAAILHNKQIQKVIPI
                     GEETDLRREFFEVIGHE"
     gene            12495..13805
                     /gene="albD"
                     /locus_tag="C7M16_RS17560"
                     /old_locus_tag="C7M16_03461"
     CDS             12495..13805
                     /codon_start=1
                     /gene="albD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391620.1"
                     /locus_tag="C7M16_RS17560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_03461"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbD"
                     /protein_id="WP_046381398.1"
                     /transl_table=11
                     /translation="MNNIIPIMSLLFKQLYSRQGKKDAIRIAAGLVILAVFEIGLIRQA
                     GIDESVLRKTYIILALLLMNAYMVFLSVTSQWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLFWLGRFSFFTVYSIIFGVVLSNHFVKKKN
                     LMFLLHAAIFACVCLSAALMPATTLPLCAVHMLWAVIIDFPVFLQAPPQQGKMHSFMRR
                     SEFSFYKREWNRFISSKAMLLNYAVMAVFSGFFSFQMMNTGIFNQQVIYIVISALLLIC
                     SPIALLYSIEKNDRMLLITLPIKRKTMFWAKYRFYSGLLAGGFLLVVMIVGFISGRPIS
                     VLTFLQCIELLLAGAFIRLTADEKRPSFSWQTEQQLWSGFSKYRSYLFCLPLFLATLAG
                     TAVSLAVIPIAGLVIVYYLQKQDGGFFDTSKRERLGS"
     gene            13795..14955
                     /gene="albE"
                     /locus_tag="C7M16_RS17565"
                     /old_locus_tag="C7M16_03462"
     CDS             13795..14955
                     /codon_start=1
                     /gene="albE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391621.1"
                     /locus_tag="C7M16_RS17565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_03462"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbE"
                     /protein_id="WP_086344631.1"
                     /sec_met_domain="Peptidase_M16_C (E-value: 6.5e-05,
                     bitscore: 20.9, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYFYGAAAYLK
                     EQIIDAFGCAAGSRFMYSANLFFDQQLKTCGTRLIHPLYNGNLHVDALLKTFADLSFPS
                     SLSFEAVEKARNELLLRIEKKFTDPFSYSAARLAEEVFGNPMYGTGMFGRRDRIKAIHP
                     KRFLDATDFIVDLVSQQKQLNILGQVQACDVRGHAPQTSAVTSGRIPVNRHIFETETRS
                     AAGPSVLTLGFDCGEMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAVYHVITRYD
                     VMNNLLLVSICTDQLHEKDIPPRVLEAVSAFHTDERELEQAKQFLRNELLLQFDSPEGL
                     LAYMGVLRRFSCTKEALLDGISAVTCRDVLQFIATINYIGAHVVRG"
     gene            14960..16240
                     /gene="albF"
                     /locus_tag="C7M16_RS17570"
                     /old_locus_tag="C7M16_03463"
     CDS             14960..16240
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="albF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391622.1"
                     /locus_tag="C7M16_RS17570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_03463"
                     /product="pitrilysin family protein"
                     /protein_id="WP_086344438.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 2.4e-13, bitscore:
                     48.2, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKAFFQQLDERTDIRYTDSGLKIFRLKFPRAHLRLCNVKIDFG
                     SRDVCIRAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNHQLSYHYQLISMLS
                     PSSPAAVFPAGRIEDIEALDISDLQKAYKAAYQAHRMTLFLIGGSENTETLLPPHLQLE
                     KRPDYHAERKIIPACPPALSQKMMLGDEERMEDTWTGLQIGALPGQNDLLSIKLYWDIA
                     ARILFQLDSPFFQEIQQTYRLEIDRLSAETYIYEDGGFLILHSQGTHSSAYIDVASYYV
                     TQKKEQVAAWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCDCSFLDMYHIIQDMDAQ
                     VFLSLIDAMASSNKAIIHVSQKEAIRQ"
     gene            16237..16938
                     /gene="albG"
                     /locus_tag="C7M16_RS17575"
                     /old_locus_tag="C7M16_03464"
     CDS             16237..16938
                     /codon_start=1
                     /gene="albG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391623.1"
                     /locus_tag="C7M16_RS17575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_03464"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbG"
                     /protein_id="WP_003243391.1"
                     /transl_table=11
                     /translation="MKQSTVFTLLLLLIGMAAYSFGWVQAVAEAAAQYVQMINNDAVRL
                     GLLACTAALLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQQHNLCSRYAEDVK
                     SLRDSYKNVRQTYVMAAVLCQVIIFGCMFEIVKAVPFRLHTPPAFSMGLAMLLILYLLF
                     CMRTYLRQLFRHGSLFRKVFAGALAAAGIWWMLSFSISELLFLIILAAIQQIGSFIYKR
                     FSYHSTASLDL"
     gene            complement(16944..18320)
                     /gene="ywhL"
                     /locus_tag="C7M16_RS17580"
                     /old_locus_tag="C7M16_03465"
     CDS             complement(16944..18320)
                     /codon_start=1
                     /gene="ywhL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391624.1"
                     /locus_tag="C7M16_RS17580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_03465"
                     /product="YncE family protein"
                     /protein_id="WP_086344439.1"
                     /transl_table=11
                     /translation="MKKNDLSVLQENCFCFCDEEISREAPFQVPIDIPEGFKVDSAEAS
                     AAVTWSTDNLSCISEPCLIQTGPEPEDIGVRYAVRVQGAITLLVSVSPVRNQYGQGDGA
                     VSVIHTEEIDQVVYYAAQSGRCPDFSQMTVEDLLIVPPFYGSPLTVAGILVLPPSPDPQ
                     SYVFTANTGDSTVSVIDADLNTIVKTIPFSAVPTNLGVTFDKAFTYILHGNTNLVSVID
                     NKTLTIINTITVGGGPRKIEFDPTDEFAYVMAAGSIYVINTASQSVIDVIPIPGALDFA
                     LDPNGQYVYTANGSSWSVDKYDVNTGQLVESIIDTFEFPSLITTPYAGNFAYVLNGELW
                     PKGVTEISLSPLSRGGDFSRLFETLRTIVFSLDSTRAYFLEPYSEPFLINNLYVVNTAR
                     QRIIANVSLPGAFDLAVTPDKQYIYAAQPNDNAVTVYRTSDYTAVTVIPVGAGPSAIAM
                     "
     gene            complement(18360..19715)
                     /gene="ywhK"
                     /locus_tag="C7M16_RS17585"
                     /old_locus_tag="C7M16_03466"
     CDS             complement(18360..19715)
                     /codon_start=1
                     /gene="ywhK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391625.1"
                     /locus_tag="C7M16_RS17585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_03466"
                     /product="YncE family protein"
                     /protein_id="WP_086344440.1"
                     /transl_table=11
                     /translation="MRKNKLSFKEKAGAEQEECLCFCEGEASREAMFQAPIELPEGFVV
                     DPAEAVANVTWNADSLSCVSDRCLIQTGPEPDEVGVQFAVRLQGTVTLLVSVSPVRNQY
                     GQGDGAVSVIHNAEIDQVVYYSDEPDDCPDISDITIENLVVVPPFYGSPLSVTGTIVLV
                     PEPEPVYAFTANPNDQSVSVIDTNTHTVVTTIALPYNPAGIEITPDKSAVFVLHPNNNV
                     ISVIDYDTLTVTATILLDQPPRLIRFIPNHEFAYVFTGTAIYVIGIDTLTVERSIPVEG
                     FDIAIDPNGLFAYVLNFGLVQKVDLSTGEVLGTIERELIVSSIETDSTERYAYVLEQEF
                     LFNYLTVIDLNTFTIRDTQELEPDGLYVMFTSGSEVYLHDSFTGNLYSVSPNGAGVIGN
                     LPQSATDYAFTPNGDFLYATRFIEQSIIVYNTDDYSVETVISLGVSPGAIAI"
     gene            complement(19712..19942)
                     /locus_tag="C7M16_RS20805"
     CDS             complement(19712..19942)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009968328.1"
                     /locus_tag="C7M16_RS20805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_024572000.1"
                     /transl_table=11
                     /translation="MQIPPFIILYMSYFIINILVRSAKKPQFFLSLHRMFGDIFSKRSF
                     YPQQFVQANTLPFHILLYLREQCMSEKEVKE"
     misc_feature    19896..19912
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.81"
                     /tool="antismash"
     gene            19945..21090
                     /gene="rapF"
                     /locus_tag="C7M16_RS17595"
                     /old_locus_tag="C7M16_03467"
     CDS             19945..21090
                     /codon_start=1
                     /gene="rapF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391626.1"
                     /locus_tag="C7M16_RS17595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_03467"
                     /product="response regulator aspartate phosphatase RapF"
                     /protein_id="WP_086344441.1"
                     /transl_table=11
                     /translation="MTGVISSSSIGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFN
                     FFRGMYELDQREYLSAIKFFKKAESKLIFVKDRIEKAEFFFKMSESYYYMKQTYFSMDY
                     ARQAYEIYKEHEAYNIRLLQCHSLFATNFLDLKQYEDAISHFQKAYSMAEAEKQPQLMG
                     RTLYNIGLCKNSQSQYEDAITYFKRAIAVFEESNILPSLPQAYFLITQIHYKLGKMDKA
                     HEYHSKGMAYSQKAGDVIYLSEFEFLKSLYLSGPDEEAIQGFFDFLESKMLYADLEDFA
                     IDVAKYYHERKNFQKASAYFLKVEQVRQLIQGGVSLYEIEV"
     gene            21074..21193
                     /gene="phrF"
                     /locus_tag="C7M16_RS17600"
                     /old_locus_tag="C7M16_03468"
     CDS             21074..21193
                     /codon_start=1
                     /gene="phrF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391627.1"
                     /locus_tag="C7M16_RS17600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_03468"
                     /product="phosphatase RapF inhibitor PhrF"
                     /protein_id="WP_041334633.1"
                     /transl_table=11
                     /translation="MKLKSKLLLSCLALCTVFVATTIANAPTHQIEVAQRGMI"
ORIGIN
        1 tttatatttg tcctggtcct cccattgctt cgggtagccg atgcccggct ttgtttctac
       61 attattgaag tacatatatt ccgcaccgga acgatttgtc cacgtgtttt tgcaggtgac
      121 gctgcacgtg tggcagccga tgcatttatc caagttcatg accataccga tttgcgcttt
      181 aatcttcaag ccaatcgacc tccttcagct tgcggatgac gacgttcagg tcgcgctgat
      241 tccccgttgg accgtaataa ttaaagccgt agctgagctg ggcgtagcca ccgatcatct
      301 gtgtcggctt gacgtgaatc cttgtcgggc tgttatgggt gcctccgcgg ttattcgtca
      361 gctttgtgcc gggcacgttg atgtggcggt cctgggcatg gtgcataaac gccattcctt
      421 taggaatccg atgagacaaa accgctctcg cgacgacaac accgtttcgg ttaaagcatt
      481 caatccaatc gttgtctttg atatccgtgt cctctgcatc atctttattc atccacacgg
      541 tcggcccgcc gcggaacagc gtcagcatcg gcagagaatc aaaatacatg ctgtggacag
      601 accatttatt atgcggcgtc aaataattga ggacgatttc ttttccctct tgatcaggcc
      661 gcttgctcag aaacgggcga tgctggagga tcggtttgaa tgtcgccatc gtttcaccga
      721 attccatcat cagttcatga tcgacataat aggattgtct gcctgtcagc gtccgccacg
      781 gaattaattt ttcaacattt gttgtaaacg gcgaatacct gcgccctcct ttttcagagc
      841 cggaaaacgc tggagacgtg atcaccgttt tcggctgggc tgtaatttgt tcgaacgtaa
      901 agcattcttc ctcgcgttct tccgccaggt ctttcagctt caggttcgtg atgttttcaa
      961 gtgattccca tgctttgacg gcgacctttc cattcgaagt ggatgatagg gttaaaatcg
     1021 cttctgctgc ctgctttgct tcacttatat tcggacatcc ctttgcgaca ctgtccgagg
     1081 tgatttctcc caatctctgt ttgagtgatt catattcatc ggctattgac cagctcatcc
     1141 cttttgttcc gctcggcttt aaagcaacgt tcggaccaag tgcagtcatt ttatgaaaaa
     1201 tgtgtttgta atcccgttca acgacttgga tgttcggcat cgtttttccc ggaatggctt
     1261 cacattcgcc tttgctccag tcattgattt tgccgaatgg ctgggccaat tcctgcatgg
     1321 tgtcatggag gagcggcgtc gcaaccactt ctttcaccgg ctccatatcg acttcttctg
     1381 ccagatcgga aacggctttt gacagcgcct tgaaaatatc ccagtctgac ttcgattccc
     1441 acggagccga gatcgcagga gcaaatggat gaatgaacgg atgcatatct gtgctgctga
     1501 gatcgtgttt ttcataccat gtcgccgccg gcagcacgat atcggaatac agcgccgtac
     1561 cggccattcg gaagtcaaga ttgattaaca agtcgagctt tccttccggc gcctgctccc
     1621 gccatttgat ttcttcaggg cggatgctgt cgctgtcgtc attcatcaaa ccgttcgtcg
     1681 tccccagcaa atgcttgaga aaatattcat gcccttttcc tgagcttgag atcagatttg
     1741 cccgccatac gaagagattt cttggaaaat tcacttcatt atcaggatct tcaatcgcga
     1801 atttcagttt tttctcttga agctgtgagg ccacgtacgc acctacgtct tcgggtgttg
     1861 ctgcccctgc tttttcagct tctttataca gatcgatgcc attttgattg aaagtcgggt
     1921 aagacggaag ccaccccagc cgcgcggcca gcacattgta atcagcgtgg tgcttgtagc
     1981 gggatgacgc agcaatcggt gatgccaaat cactgatcgg ctggtcctca taacgccact
     2041 gatctgtcgc aaagtagaaa aatgaggtgc cgttttgcag cttaggcacg ccctcccagt
     2101 cctttgcagt tgcaatcgtc tgccaccctt cagcaggtcg gagcttttcc tgccccacgt
     2161 aatgggccca gcctccgccg tttacgcctt gggcgcctac aagtaaaaca agatttaaca
     2221 ccgctcggta gatcgtgtcg gagttgaacc agtggttaat gccggcccct acgataatca
     2281 tggaccggcc atctgtatcg atcgcatttt gggcaaactc tctggcaatc ttaacgacag
     2341 cttctttttt gattcctgtc atttgttcct gccaggcagg cgtaaacggc tcaggatcat
     2401 cataggagac agccgatcgt tcgccgatgc cccggttcac gccgtagtta gccagtatca
     2461 agtcaaacac ggtcgtgatg tacgtttctt caccgttcag gttcattttt ttaataggaa
     2521 gatcccgctc gagcactttg tttccgtcat ttgaaaaata cgggatgcgc accgtgccga
     2581 tttcgtcctc tattcccagc acagagagac ggggttcaat cggttccccg gtttcttcat
     2641 caatcatgtg caggttccat ttctgctgcc cgtcccagcg cgagcccatt gtcccttggg
     2701 gtatggcaaa tgaacttgtc tgttcatccc aaactgcagg cttccactga tcatgctttg
     2761 tcttccgccc gatgtccttc gcatgcagaa accgtcccgc tgtgtatacg ccattttctt
     2821 ttgacagagt gacgagaaat ggaaaatcag tgtattgctt cgcgtactca ataaaacgtt
     2881 cagtttcttg gttcacgtaa aattcctgca gaataacgtg acccatcgcc atcgcaagcg
     2941 ccccgtcagt cccttggcga atactcagcc agtcatccgc gaactttgag gattccgcaa
     3001 aatctggact gatcgaaatg accttagcgc ctttatagcg ggcctccgcc aaaaaatgcg
     3061 cgtcaggcgt tctcgttaac ggaacgttgg agccccatgt gataatatag ccggaattgt
     3121 accaatcact gctttccgga acgtccgtct ggtcacccca aatttgcggg gatgctggag
     3181 gaagatccgc ataccagtca taaaaactga gcatagggcc tccgattaac gacataaacc
     3241 gggagcctga tgcgtggctg atcatggaca tggccggaat cggagaaaaa ccgacgtttc
     3301 ggtcaggccc gtatttcatc actgtataca gcagagaggc tgaaatcagc ttcagcacct
     3361 ccggccattc agcgcgcaca aaaccgcctt tccctctcgc ctgtttatag gacttcgctt
     3421 tttcagggtt ttcgacgatc gatttccagg cttccaatgg attttgatgc gtctgcaatg
     3481 cctcccgcca caaattgatc agcacaccgc gcacgtatgg atatttcaca cggagcgggc
     3541 tgtagatata ccatgaaaaa ctggcccccc gcgggcagcc tctcggttca aaatcaggca
     3601 tatccgagcc tgttgatgga taattcaaat tttgcccttc ccacgtgaca attccgtttt
     3661 tcacataaat attccagctg caagaccctg tacagttgac gccgtgggtg gagcgaacga
     3721 ctttgtcgta ctgccatctg tttctgtata cattctccca atcgcgatcc tcgcgggtag
     3781 tttggctatg tttatttgaa tggtgttcga taggagagaa ataattcaat ctcctaaaca
     3841 acggactcat tttctttttc ttcatgagag ttcactcctt ccgagtcagg tgatgctaag
     3901 ttcactataa acagagacag cgtgttttct tgtgaactat gtcacacact ctgctttttt
     3961 cacaaaatgt tcacacaaag gagaaggaag gcttttcaca ggatatgagg aaggctgcgt
     4021 tcaggcagga cgcttgggtc attagccgcc tttcattcaa agatcaaaaa aaaccggctc
     4081 tatttaagaa ccgggctcgg cgttttcatc ctgtgatgta tgcagatacc gcaaaaataa
     4141 ttgataggaa caaaaaacat tttgctgaag catagccaaa aagttcattt gcagctgcgg
     4201 atgataagac atcattttct taaatatgta atatgggatg ttgagaatca gaatgtctga
     4261 agtggcattg actgagataa agggcgataa ataaagcccg cctttttcat caatcggaaa
     4321 cacatcgcct ttttcccaca gcgcaacggt tttcgaccct tcagggagcc ttgtgtccat
     4381 aaaacggaca ctgcctttta atacaatata aacagattga gaatgaagaa aagatggaga
     4441 ctgatcacat gaaccgcgga taaacgtgcc gtttttcagc aaggtttcga caatggatag
     4501 aggcacttca ttaaacatag gaagttgttt cagaaataat aaatagtcac actgattcat
     4561 aggaaaacct cctgtgctaa ggatagcttt agtgtagctc gactgagcct gtacagcagt
     4621 gatgtatttc acagcctgta tgatgaatgt cacttatcag gagggtgaat gcatttataa
     4681 tgaaagaaaa aaggaggatt tcgatgaagg cgctgattcc gaagcagcac ggggcgtggg
     4741 cgatgctgct gatcccattt ttactcggca tggtcaaggg aggccccgtt atttggcata
     4801 ttccgctctt ccttggttgg cttttcctat acttagcggt ttatcccgtt acgcttgcct
     4861 taaaaaagaa acaaagcaaa ccatatcaaa agtggatgtg ttattacggt tttcccgcct
     4921 gctgcttttt gatgatctcg gtctttcata agccgcctct catctgggtg ggcgtttctt
     4981 tactgccgct gtttctcata catatgtatt ttgcccgcag aaaaaacgaa cgagccttat
     5041 tgaatgatgt tgcaggtgtc ttgttctttt gttcgggcgg gtttgcgagc tgctggctgg
     5101 ggatgggaac ccttgacggc tgggcttggt ttattttctt gcagtctgct ttatttttta
     5161 tcgggagttc cttttatgtg aaatcggtga tccgcgagag aaaaaacagg gcatttgcat
     5221 actggtcatg gggatatcac ctgctgctcc cctttttatc cgctcttttc ggagcaggat
     5281 gggcgtttct cgcttttatc ccgagcagct tgcgggcatg gttttttcat ggaagggatt
     5341 ggcccgtaaa aacgattggc attctggaaa tcgtgaatgc ctgcttcttt cttgccgtca
     5401 tgtgcctgtt tatcacaagg taaaaaaaca aggacaccgc tgtccttgtt tttttcagtc
     5461 aatattgcaa atctccagcg ggcaattttc acactcaatc tcacatcgta aatagtcccg
     5521 cttgtgcaaa ataatttttc cggattcgtc tatcgaaata accccttttt tgcggagatc
     5581 tccgagcata cgattgacgc tttcccgtgc agccgcgcaa aactttgcca aatcctgatt
     5641 tgtcaggaca atgttaatca gaatgccgtc gcttcgctcc actccgtagc tgtttgataa
     5701 acggataagg gtggaataga gcgccccctt tttgccatga agaagcagat ccctgatttt
     5761 ggactgaatc ttccggaggt gcgtgctcat ccatttcatg aactcaaatg tcaaagcgcc
     5821 gttttggatt aattcttttt ccagcttatt tttattaatg acgagcacct cgccatcctc
     5881 tagcactttt gcactgagca tatacctcgg ttcttcagtg aaaagtgtta attctccgac
     5941 gatatcatgc ttttggcaga ttctaagcgt caggtctttt ccgtcagatg tcagcttgcc
     6001 gatttcaatg agtcctgatt gaatcagata aagctcttct gcatccattc cttctcgaaa
     6061 caaatacgtg tgtttttcca tttttctttt cgtgctgatc gattccagca gttcatgcag
     6121 atcgctggat ataagatcac tatcagatgg tcgaacagag agaaaattca tgagctcacc
     6181 tcgaagaaag tcacgttgtg tgtttattgt aacgtgaatt gatttgtacc catcgagaaa
     6241 aaactaacaa tcttgtgaat gccccagtgt tagttgatgc tctggctgtt tctctccgtg
     6301 tgtgttttca ttctttcctg ccaatacatc catatgacaa ggacaaaact ggctaacgcc
     6361 acctctgaaa gcgccataaa cccgatcgcg tactggcctg ttgcctgaaa tacactcgcc
     6421 aatatgagcg gaggaaaaaa gccgcctaat ccgcccatgg cagacacaat cccattggca
     6481 atccccgctt gcttcgaaaa atagaaaggc accagtttaa aaacagtccc gtttcctatg
     6541 cctgagcaga cggccacggt taatgatcca aacgtataaa ggccgattgt cggcgagaac
     6601 gataggataa tgcctgataa tgtaagcccg gcaaaaacaa acatcaagat gcggagcggg
     6661 ctcattttat cagccaggaa tccgcctgca ggcctgagca gcgtagaaac cgcaataaag
     6721 ccagccgtcc gcaagccggc atctgcagga ttcagcccaa aatgctccac cagaaagttc
     6781 ggcagataga tagtgaaggc gacaaaggca ccgaacgtaa taaaataaaa caggctcaga
     6841 aaccatagca catgattccg gtaaacggct ttgatttgag tcttaacaga aactttgacc
     6901 ttcttctcat gcctgtcacc gaacaaaacg tgcagtaagg caaagacagc cagcaaaacc
     6961 agatacatct gcacggttga tttccacccg acggcttgag cgataaccgg cgctgcaaat
     7021 gtcgtaacgg ctgtcccgat atttcctgca ccgtaaatcc cattgacgac accgtgcttt
     7081 tctttcggat aatatttcgg gagggaggtc accccaatgg aaaacaccgc tcccccgatc
     7141 cctaagaaaa agccgcctgc gattaaatca aacagagaat ccgcgatact gatccaaaat
     7201 acaggaaata aaagcaggat gaagctaacc ataaacatga gccgcgcgcc aaacctgttc
     7261 gttaaatacc ctaaaggaat gcggagaagc gacccgagga tcacaggaat cgccgtcacc
     7321 aaagaaatct cacccttgct taaatgaata tctaatgtga tttgggaaat gagtgatgaa
     7381 atcagcaccc aaaccataaa ccctgccacc aagcttaatg actgtaacga taattgaatg
     7441 tgttgacggt tgatcatttg gcttgcccct ttcaatgatt caataatcag tcttatcata
     7501 caaaaactag ccaaacagga ttgtgaatta catcacacgt ttttctcata aaaaaaggac
     7561 aaagcccgaa gactttgtcc ttttgatcgt gattacattt tttccggagc cgatacgccg
     7621 atcagctgaa gcgcattgtt cagcgtaatt tgcgttgcct tcattaaagc caggcgcgcg
     7681 cggcttttct cttcattttc agggtcgatg actttctctg cgttgtagaa gctgtgcaga
     7741 gcagaagcca gatcataaat atagttagtg acacggtgcg gaattcgttt ttccgctgct
     7801 tccgccactg cctctgggaa gccgccgatc gttttcagca gatcgtattc tttttctgat
     7861 tgaatatggc tgaaatcaag atctgccgcc ggtttaagcc cctgctcttc cccttggcga
     7921 agcatgctgc aaatacgtgc atgcgcgtat tgtgcataat acacagggtt ttcgttagat
     7981 gttgatacag caagatctaa gtcaaaatcc atatgggtgt ctgcacttcg cattgcaaag
     8041 aagtaacgca cggcatccaa gccgacttct tcaatcaggt cacgcatcgt tacggcttta
     8101 ccggtccgtt tgctcatttt cattttctcg ccgtttttgt aaaggtgaac gagctgaatg
     8161 atttctactt caagcgttcc tttttcatac cccagcgctt cgattgccgc tttcatacgc
     8221 gggatgtagc cgtggtgatc ggcgccccaa acgttgatca gcttatcaaa gccgcggtca
     8281 agcttgtcct tatgatacgc gatatcagga agcaggtacg tgtacgtgcc gtccttcttg
     8341 atcaatacgc ggtctttatc atcgccgaac gtcgtggaac ggaaccaagt cgcgccgtct
     8401 tcttcataga catggccttt ttcgcggagc gcttcaagcg ccttgtcgat ttttccattt
     8461 tggtacagtg aagtttctga ataccacaca tcaaacggca cacggaagtt ttccaagtcc
     8521 ttgcgaagct tttccagctc gtatttcagg ccgtattcac ggaaaaacgc gaggcgttca
     8581 ctttcctctt cgttaacgaa acggtcaccg tattcctcag cgagacgctt tccgatcgca
     8641 atgatatcct caccgcggta gccatcctcc ggcatcggtt tttccaatcc gagtgcttca
     8701 aagtaacgga cttcaacaga aagcgccaga ttgttgattt ggtttcccgc atcgttaatg
     8761 tagtattcgc ggcttacatc gtaacccgct tttgaaagca cgttgcacaa ggaatcgccg
     8821 acagccgccc cgcgcgcatg cccgaggtga aggtctcccg tcggattcgc tgatacgaat
     8881 tctacctgaa ctcgttcacc gtttccgatg ttcgtttccc cgtatgcttc ccctgcttcc
     8941 agtacagacg gaatcagctt tgttaaatat tgattgttca tatagaaatt gataaaaccc
     9001 gggccggcga tatccagttt ttcaatcgaa gccttccctt tatcaaaatg ggcgacaatc
     9061 tcttcagcga tttgacgcgg cgcttttttt gccactcttg ccaactgcat cgccatattc
     9121 gttgagtagt cgccgtgtgt tttatctttc ggtgtttcta aaacaacatt gggaatctgg
     9181 ctttcttcag ccagtcccgc tttcagaacg gccgctttga tttcttcttt cagcacgtcc
     9241 ttcatttgtt ccgcaatgtt catgcgtgag ttcctccctc atacgtgatc gtcatattat
     9301 gtaaatgctc ctgctcgtct ccgacatgca tgtcatatgc gatgctgata cggccttttt
     9361 cttcatcgag atcagattga atcgattttg tgcttgtttt cagctcaagc tcaccaaatg
     9421 acattttata tttagcaatt gtggaagctc ccgttacgaa acgctgattc attttgacag
     9481 cgcctgacct catgaccagg acttcgcctt cgcttacttt cacaatcgtt ttgactttgc
     9541 ctaagtcgtg ttcttcataa taagatagat acactttatt ttgttttaca tagtaaaatc
     9601 cggtggtgcg gaattcgatg acttcttggt ttccgtcatc ctcgatcaca gacttcacat
     9661 ggagtgttat cggtgtctct tgcttcattc tgacacgtcc ttttcatcat tccactttga
     9721 cttgaatagt ataatcattc ggtttgtaaa cttcaactgc ttctatctta ccatcattgc
     9781 tcatcagatt tgaagataaa cctcataaaa agcatttcct tatatagaag agaaaatcat
     9841 atcactaatt acctttagga aatgttacat ttttccgaaa tctatcattt ccttttcaca
     9901 tttttttcaa aatatatgta ttgaattagt aatttgatag ttttaagata aaagtacaac
     9961 atagatctgc tagaaaaaca aaaaaaggga ggattcaatt atgaaaaaag ctgtcattgt
    10021 agaaaacaaa ggttgtgcaa catgctcgat cggagccgct tgtctagtgg acggtcctat
    10081 ccctgatttt gaaattgccg gtgcaacagg tctattcggt ctatgggggt aaggatctcc
    10141 caaaagggca tagtcattct actatgccct ttttaagtaa attacaattt ttaactaaaa
    10201 tctacctctt ggatatacat acacaaccgt ttttcatttg aatcatatgt ataggggatg
    10261 gtattttgtt tatagagcag atgtttccat ttattaatga aagtgtaaga gttcaccagc
    10321 ttcctgaggg cggcgtgtta gaaatcgact acttgcgcga taatgtctcc atttctgact
    10381 ttgagtattt ggatctcaac aaaacggctt acgagctctg catgcgcatg gatggccaaa
    10441 aaacagctga gcagatttta gctgagcaat gtgcagtgta tgatgaatca ccggaagacc
    10501 ataaagattg gtattacgac atgctcaaca tgctccagaa caagcaggtg atccagcttg
    10561 gaaaccgggc cagccgccgt acaatcacca cgagcggaag caatgaattt ccgatgcccc
    10621 tgcacgccac ctttgaactg acgcaccgct gtaatttgaa atgcgcccac tgttatttgg
    10681 aaagctcacc tgaagcgctc ggcaccgtgt cgattgagca attcaaaaaa acggctgata
    10741 tgctgtttga taacggtgta ttgacatgcg aaatcacagg cggagaaatt tttgtccatc
    10801 caaacgccaa tgagattctt gactatgtgt gtaaaaagtt caaaaaagtc gctgtcttaa
    10861 caaacggaac actcatgcga aaagagagcc tggagctttt gaagacttac aagcaaaaaa
    10921 tcatcgtcgg catttctcta gatagtgtca attccgaggt ccatgactcc tttagaggga
    10981 gaaaaggctc ttttgcccaa acttgtaaaa cgataaaatt gttgagtgac cacggtatat
    11041 ttgtcagagt cgctatgtct gtcttcgaaa aaaacatgtg ggaaatccac gatatggccc
    11101 aaaaggttcg ggatctcggg gcgaaggcgt tctcttacaa ttgggttgat gatttcggaa
    11161 gaggcaggga tattgtccat ccaacgaaag acgccgagca gcaccacaag tttatggaat
    11221 acgagcaaaa tgtgattgat gagtttaaag atctgattcc gattattccc tatgagagaa
    11281 aacgcgcggc aaattgcggc gctggctgga agtccattgt gatcagcccg ttcggcgaag
    11341 tacgtccttg cgccctcttt ccaaaggaat tttcattggg aaatattttt catgattcct
    11401 atgaaagcat ctttaactcc cctctcgtcc ataaactgtg gcaagcgcag gcgccgcggt
    11461 tcagcgaaca ttgcatgaaa gacaaatgcc cgttcagcgg ctattgcgga ggctgttact
    11521 taaaagggct gaactctaac aaatatcacc ggaaaaacat ttgctcttgg gcgaaaaatg
    11581 aacaattaga agacgtggtc cagcttattt aggagggaaa cgatttgtca ccagcacaaa
    11641 gaagaatttt actgtatatc ctttcattta tctttgtcat cggcgcagtc gtctattttg
    11701 tcaaaagcga ttatctgttt acgctgattt tcattgccat tgccattctg ttcgggatgc
    11761 gcgcgcggaa ggctgactcg cgatgagcat tttggatata cacgatgtat ccgtttggta
    11821 tgaacgggac aacgtcatct tagaacaagt ggatttacat ttagaaaaag gcgccgttta
    11881 cgggttgctt ggggtaaacg gcgccggaaa aacgacactg attaatacgc tgacaggcgt
    11941 gaaccgcaat ttcagcgggc gctttacact gtgcggaatt gaagcggagg ccggcatgcc
    12001 gcagaaaaca tcagatcagc tgaagactca ccgttacttc gccgccgatt atccgctgct
    12061 atttacagaa attacggcga aggactatgt gtctttcgtc cattcgcttt atcaaaagga
    12121 tttttcagag cagcagtttg ccagtttggc cgaggccttt catttttcga aatacatcaa
    12181 taggagaatt tcggagctgt ccttggggaa caggcaaaag gttgtattga tgacaggctt
    12241 attgctgcgc gctcccctgt ttattttgga tgagccgctc gtcggtttgg atgtggaatc
    12301 gatagaggtt ttttatcaga aaatgcgcga gtactgtgaa gcaggcggga ccattttgtt
    12361 ttcttctcat ctgctcgatg tcgtgcaaag attttgtgat tatgcggcta ttcttcacaa
    12421 caaacagatt caaaaggtca ttccgattgg agaggagacc gatctgcggc gggaattttt
    12481 tgaggtgatc ggccatgaat aacataatcc ctatcatgtc tttgctgttc aaacagcttt
    12541 acagccggca agggaaaaag gatgccatcc gcattgccgc aggccttgtc attctggccg
    12601 tgtttgaaat tgggctgatc cgccaggccg gcattgatga atcggtgttg cgcaaaacgt
    12661 atatcatact cgcgcttctc ttaatgaacg catatatggt gtttctttct gtgacatctc
    12721 aatggaagga atcttatatg aaactgagct gcctgctgcc gatttcttca cggagctttt
    12781 ggctcgccca gagtgtcgtt ttgtttgtcg atacctgttt gagaagaact ttattctttt
    12841 ttattttacc gctgttctta tttggaaacg gaacgctgtc aggggcgcaa acattgtttt
    12901 ggctcggcag gttttcgttt tttaccgttt actccattat tttcggagtt gtgctaagca
    12961 accacttcgt caaaaagaag aacttgatgt ttctgctgca tgcggcgata ttcgcctgtg
    13021 tatgtctcag cgccgctttg atgccggcca ccacgcttcc gctttgcgcg gttcatatgc
    13081 tgtgggcggt gatcattgac tttcctgtct ttctgcaggc gcctccgcag cagggcaaga
    13141 tgcattcatt tatgcggcga tctgaatttt cgttttacaa aagagaatgg aaccgattta
    13201 tctcttctaa agcgatgctg ttaaattacg cggtaatggc ggtattcagc ggcttctttt
    13261 cgttccagat gatgaacacc ggcatcttca atcagcaagt gatttatatc gtgatttccg
    13321 cgcttttgct catctgctcg ccgatcgccc ttttgtactc gattgaaaaa aatgaccgga
    13381 tgttgctcat cacgcttccg atcaagcgga aaacgatgtt ttgggcgaaa tatcgctttt
    13441 attcaggcct attggcaggc ggatttctcc ttgtcgtgat gattgtgggt ttcatcagcg
    13501 gccgtccgat ttcagttctc acttttttgc agtgcattga gttgctgctg gcgggagctt
    13561 ttatcaggtt aactgcggat gaaaaaaggc cctccttcag ctggcagacg gagcagcagc
    13621 tatggagcgg tttctcaaaa tatcggtctt atctgttttg tcttccccta ttcttagcca
    13681 cattagccgg caccgctgta tccttggcgg tcattccgat agccggtctg gtcatagtct
    13741 attacctgca aaaacaggat ggtggtttct ttgatacaag caaaagagaa cggcttggaa
    13801 gttaacctgc tgaagactca tcaattttca actatatcaa tcgccgcgag ctttctgaaa
    13861 ccgatcgaaa gcgcggcgga acctgaggaa gaaacaattt atttttacgg cgccgccgcg
    13921 tacctgaagg agcaaatcat tgacgctttc ggttgtgctg ccggcagccg tttcatgtac
    13981 tcagcgaatc tcttttttga tcagcagctg aaaacctgcg ggacccgttt gattcaccca
    14041 ttatataacg ggaatcttca tgttgacgcc ctgctgaaaa cttttgcaga cttgtctttc
    14101 ccttcttctc tttcattcga agcagttgaa aaggccagga atgagctgct gctgagaatc
    14161 gaaaagaaat tcactgatcc tttctcctac tcggcggcgc gcttggctga ggaggtcttc
    14221 ggaaacccga tgtacggcac aggcatgttt ggccggagag acaggataaa ggcgattcat
    14281 cctaaacggt ttctcgacgc aacggacttt atcgttgatt tagtgtccca gcaaaaacag
    14341 ctgaacatat tgggacaagt acaagcatgt gatgttcggg gacatgcccc gcaaacgtcc
    14401 gctgtaacgt ccggaagaat acccgtaaac cggcatattt ttgaaacaga gacacgcagc
    14461 gctgcaggtc cttccgtctt gacactcgga tttgactgcg gagagatgaa agatgccagc
    14521 gattatatca aaatacagct aatagacgga ttactgggaa agtacggcca ttccgcttta
    14581 ttcaagcact tcagagagaa ggatctggca gtctatcacg ttatcacccg ttacgatgtc
    14641 atgaacaatt tgctgcttgt ttcaatatgt acagatcagc ttcatgagaa agacattccc
    14701 ccgcgcgttt tggaagctgt ctcagctttt catacagatg agcgggaact agaacaggca
    14761 aagcagtttt tacgcaatga attgctgctg caattcgatt ctcccgaagg tctattggcc
    14821 tatatggggg tcctgcgccg cttctcctgc acgaaagaag ccttgctgga tggcatctca
    14881 gcggttacat gccgtgatgt attgcaattc atagcgacca tcaattatat cggagctcat
    14941 gtagtaaggg gatgaagaga tggaaaagaa agcctttttt caacagctgg atgaacgaac
    15001 cgatatcaga tacacagaca gcggactaaa aatattcaga ttgaaattcc cccgcgccca
    15061 cctgcggctg tgcaatgtaa aaatcgattt tggaagccgg gatgtatgta tacgggcaga
    15121 atccggtgat acactgcttc cgtatggcac agcacatttt ttagagcatc ttctcttctg
    15181 gcataacggc cgcaatctgt acagtgattt ttttgcgcat ggcgcgcttt taaacgcatt
    15241 cactacctac accgatacca atttcatgtt tacctcatta ccggatcggc tcagacaaac
    15301 gattcccatc ctgcttgatg ctttatggaa ccactcattt gacaagaaga ttgtcgctca
    15361 ggaaaaagct gtgattacaa gcgaaattca aacagcacac cttaaccatc agctctcata
    15421 tcattatcag ctgatcagca tgctttctcc ctcctcacca gctgccgttt tccccgcagg
    15481 cagaatcgaa gatattgagg cgctggacat cagtgattta caaaaagcct ataaggctgc
    15541 ctaccaagcc catcggatga cgctgttttt gattgggggc tcagaaaata cagaaacgct
    15601 tttgcctcct cacctccagc tggaaaagcg tccggattat catgctgaaa gaaaaatcat
    15661 cccggcatgc cctccagccc tctcacaaaa aatgatgctg ggtgatgagg agcggatgga
    15721 agatacctgg accggattac agatcggcgc acttcccggg caaaacgatc tgttgtcgat
    15781 aaagctttat tgggatatcg cggctcgtat tctatttcaa ttagattcac cgttttttca
    15841 agagattcag caaacgtacc gcctggaaat cgatcgcttg tcagccgaga cttatatata
    15901 tgaggatggc ggtttcttga tccttcacag tcaagggacc cattcttcag cttatatcga
    15961 tgtggcttca tactatgtca cacagaagaa agaacaggtt gccgcctggc ttcaatacgg
    16021 caaggactct ttgacagacg cgatcattta tgacagcgat tatgtgcgta aatgcttcga
    16081 gtgggcagcc gagtgtgaca ggtgcgattg ctcgtttctt gacatgtacc acatcattca
    16141 agatatggat gcgcaggttt tcttgtctct cattgatgca atggcatctt ctaacaaagc
    16201 gatcattcac gtttctcaga aagaggcgat cagacaatga aacaaagcac tgtctttacc
    16261 cttttattgc tgcttatagg tatggcggct tattccttcg gctgggttca ggccgttgcc
    16321 gaagccgccg cccaatatgt acagatgatc aacaatgatg ctgtgcggct cggactgctg
    16381 gcttgtaccg ctgccctcct gatgctgcct gcttttctct atcttcacta tgtcacccaa
    16441 tccgtgaaaa acatgacagc agcttttcag aaactcacac agtctcatca aagctgctgt
    16501 gactttcagc aacacaactt gtgcagccga tatgcagaag acgtcaaatc gctgcgtgac
    16561 agctataaaa acgtccgcca aacatacgtg atggctgccg tgttgtgcca agtcatcata
    16621 ttcggctgca tgttcgaaat cgttaaagcc gtccctttcc gccttcatac gccccctgcc
    16681 ttttcaatgg gacttgcgat gctactgatc ctgtatttat tgttttgcat gcgaacgtat
    16741 ttgcggcagc ttttccggca cggcagcctg ttcagaaaag tgtttgcggg agcactggca
    16801 gcagccggga tttggtggat gctcagtttc tctataagtg aactgctgtt tctgattatc
    16861 ctggctgcca ttcagcaaat cggatcattt atttataaac gattctctta tcacagcacc
    16921 gcttctcttg atctataaaa tagctacatc gcaatcgcag acggacccgc gccaaccgga
    16981 atcaccgtca cggctgtata atcacttgtg cggtacacgg tcacagcatt gtcgttgggc
    17041 tgtgccgcat aaatatactg tttgtccggc gttacggcga ggtcaaaggc gccggggaga
    17101 gacacgtttg caatgatcct ctgtctggcc gtattaacta cgtataagtt attaatgaga
    17161 aacggttcac tatatggctc tagaaaataa gctctagtac tatcgagaga aaatacaatc
    17221 gtcctcagcg tttcaaataa acggctgaag tcccctcccc tgcttaatgg tgacaaacta
    17281 atctccgtta cacctttcgg ccacagctca ccattcaata cgtacgcaaa atttccagcg
    17341 taaggagttg taattaaact gggaaattca aatgtatcta tgatactttc taccaactgc
    17401 ccagtattta catcatattt atcaaccgac caactgcttc cattagcggt atagacatac
    17461 tgtccattcg gatcaagagc aaagtctaaa gcgccgggta tcggaatgac atcaatgacc
    17521 gattgagagg ccgtgttaat cacatatata gatccggcgg ccatcacgta tgcgaactca
    17581 tctgttggat caaattcgat ttttctcggc cctcctccaa cagtaatggt atttatgata
    17641 gttaatgttt tattatcaat cactgagaca aggttggtat ttccatggag gatatacgtg
    17701 aatgctttat cgaaagtaac gcctagatta gttggcacag cagaaaacgg gattgttttt
    17761 acaatagtgt ttaaatctgc atcaatgact gaaaccgtgc tgtctccagt attggcagta
    17821 aacacatacg attgagggtc tggcgatggc ggtaaaacaa gtatcccggc caccgtgagc
    17881 ggactgccgt agaaaggcgg cacaatgaga agatcttcca ctgtcatttg actaaaatca
    17941 ggacagcggc cagactgtgc tgcataataa acaacttgat caatctcttc agtatgaatc
    18001 acagaaacag ccccgtctcc ttgtccatat tgatttcgta caggcgacac actgacaaga
    18061 agcgtaatgg ccccttgtac tctcacggca tatcgaacac cgatatcttc tggttccggc
    18121 ccagtctgga ttaagcaagg ctcactgata caggacaaat tgtctgtact ccatgtaaca
    18181 gccgctgacg cttcggccga atcaaccttg aagccctcag ggatatctat cggcacttga
    18241 aacggcgctt cccggctaat ttcctcatca caaaaacaga aacaattttc ctgtaaaaca
    18301 gaaagatcat tctttttcat gatttcacgt ccttttagaa atgcaccaca catagttgat
    18361 taaatcgcaa tagctcccgg tgaaacccca agagatatga cagtctccac ggagtaatca
    18421 tccgtgttgt aaacaatgat gctctgctct ataaaacgag ttgcatacag aaaatcgcca
    18481 ttcggggtaa acgcatagtc tgttgctgat tgcggaagat ttccaattac acctgctcca
    18541 ttcggactga cagaatataa attgccagtg aagctgtcat gtaaatacac ctctgatcca
    18601 ctcgtaaaca ttacatatag cccgtcaggc tccagctctt gggtatccct gatcgtaaac
    18661 gtatttaaat caataaccgt caaataattg aataagaatt cttgttctaa tacatacgca
    18721 taccgctccg tagaatctgt ttctatggat gatacgataa gctctcgttc aatcgttcct
    18781 aagacttcac cggtagataa gtccactttt tgcactaacc caaaattaag aacataggcg
    18841 aacaacccat tggggtcaat tgcaatatca aaaccttcta caggaataga cctctcaaca
    18901 gtcaacgtat caattccaat cacataaatg gcagtaccgg tgaaaacata agcaaactca
    18961 tgattaggga taaatctaat caatcgaggc ggctgatcca gcaatatagt tgctgtcact
    19021 gttaatgtgt cataatcgat gacagaaatc acattattgt tgggatgtaa gacaaacaca
    19081 gcgcttttat ctggcgtaat ttcaatacct gccggattgt acggaagagc aatcgttgtc
    19141 acaacagtat gggtgtttgt atcaatcaca gaaactgatt gatcatttgg attcgctgta
    19201 aacgcgtaga cgggttccgg ctccggtaca agcacaatcg tccccgtcac cgataaagga
    19261 ctgccgtaaa acggcggaac aacaacaagg ttctcaatcg tgatgtcact gatatccggg
    19321 caatcatccg gttcatcgga ataatagacg acttgatcga tttctgcatt gtgaatgacg
    19381 gaaacagccc cgtccccttg tccatattga tttcgcacag gtgagacact gacgagtagc
    19441 gtaacggttc cctgcaggcg cactgcaaat tgaacaccga cctcatcagg ctctggcccc
    19501 gtttgaatta agcaacggtc actgacacaa gaaaggctgt ctgcattcca cgtcacgttt
    19561 gcaacagctt cagccggatc aacgacaaat ccttcaggta attcaatcgg cgcttgaaac
    19621 atggcttctc ggcttgcttc tccctcacaa aaacataagc actcttcttg ttctgctcct
    19681 gctttttctt taaaggaaag cttatttttt ctcattcctt cacttccttt tcagacatac
    19741 actgctcacg cagatataac agaatatgga agggtaacgt gtttgcttgt acaaattgct
    19801 gagggtaaaa gcttcttttt gaaaatatat ctccaaacat gcggtgtaac gaaagaaaaa
    19861 attgcggttt ttttgcgctt ctcacaagaa tgttgatgat aaaatatgac atatatagaa
    19921 ttatgaaggg agggatttgc aaacgtgaca ggtgtcatat cttcttcttc catcggagaa
    19981 aagattaacg aatggtatat gtacatacgc cgattcagca tacccgatgc agaatatttg
    20041 cgacgagaaa tcaagcaaga gctggatcaa atggaagaag atcaagacct tcatttgtac
    20101 tattcactga tggagtttcg gcacaacctg atgcttgagt accttgaacc gttagaaaaa
    20161 atgaggattg aggaacagcc gagactgtct gatctgctgc ttgagattga taaaaaacag
    20221 gctcgtttaa ctggtctgct tgagtactat tttaatttct tcagaggcat gtatgagctg
    20281 gaccagcggg aatatctgtc ggctattaaa tttttcaaaa aagccgaaag caagctgata
    20341 ttcgttaagg atcggataga gaaagctgag tttttcttta agatgtctga atcttattac
    20401 tatatgaaac aaacgtattt ttcaatggac tatgcacggc aagcatatga aatatacaaa
    20461 gaacatgaag cttataatat aagattgctg cagtgtcatt ctttatttgc caccaatttt
    20521 ttagatttaa aacagtatga ggatgccatc tcacattttc aaaaagctta ttctatggca
    20581 gaagctgaaa agcagcccca attaatgggg agaactttgt acaatatcgg gctttgtaaa
    20641 aacagccaaa gccaatatga ggatgccata acttatttca aaagagcaat agctgttttt
    20701 gaagaatcaa atattcttcc ttccttacct caagcgtatt ttttaattac acagatccat
    20761 tataaattag gaaaaatgga taaagctcat gaatatcata gtaagggaat ggcttattca
    20821 caaaaggccg gagatgtaat atatttatca gagtttgaat ttttgaaatc tttatactta
    20881 tcaggcccgg atgaagaagc aattcaagga ttttttgatt ttctcgaaag taaaatgttg
    20941 tatgctgatc ttgaagattt cgctattgat gtggcaaaat attatcatga acgtaaaaat
    21001 tttcaaaaag cttctgctta ttttttgaag gtggaacaag taaggcaact tattcaagga
    21061 ggagtgagtt tgtatgaaat tgaagtctaa actattactc tcttgtctgg ctctatgcac
    21121 tgtgttcgtg gcaacaacta ttgcaaatgc acctacacac caaattgaag ttgcacaacg
    21181 aggaatgatt taaccgccgt ccatcggcgg tttttttgtc ccctctttac ccagtctccc
    21241 aatccatgct atgatttttt caataatctt aaaaatagtg gaaatgcagc atgtctctgg
    21301 aaagtgtgag aacccacttt aaacagtgga atcgagaaaa tgatgtgacg gagttcgaaa
    21361 cgtcgagcgc gacagttgaa caggcagctg agacgaccgg cgtgagcccg gctagaatcg
    21421 ccaagaccct gtccttcaga ggggaaggag atcaggtgat tctgattgtg acagccggcg
    21481 atgccaagat cgacaacaaa acgttcaggc aacatttggc tttaaagcaa gaatgctctc
    21541 tcctaatgag gtactggagc agacaggcca tgaaattgga ggagtttgcc catttggatc
    21601 ggctcatgat cc
//
