LOCUS       NZ_CP028201            20828 bp    DNA     circular CON 22-JUN-2024
DEFINITION  Bacillus subtilis strain SRCM102753 chromosome, complete genome.
ACCESSION   NZ_CP028201
VERSION     NZ_CP028201.1
KEYWORDS    RefSeq.
SOURCE      Bacillus subtilis
  ORGANISM  Bacillus subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 4025706)
  AUTHORS   Jeong,D.-Y.
  TITLE     Bacillus subtilis SRCM102753 having probiotics activity species
            isolated from traditional soybean paste
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4025706)
  AUTHORS   Jeong,D.-Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-MAR-2018) Functionality Evaluation Team, Microbial
            Institute for Fermentation Industry, Minsokmaeul-gil 61-27, sunchang
            56048, Korea, Republic of
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. v3.0
            Expected Final Version            :: yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009913255.1-RS_2024_06_22
            Annotation Date                   :: 06/22/2024 02:37:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,123
            CDSs (total)                      :: 4,002
            Genes (coding)                    :: 3,910
            CDSs (with protein)               :: 3,910
            Genes (RNA)                       :: 121
            rRNAs                             :: 10, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 58 of 92
            Pseudo Genes (incomplete)         :: 42 of 92
            Pseudo Genes (internal stop)      :: 14 of 92
            Pseudo Genes (multiple problems)  :: 19 of 92
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:16:20
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 937492
            Orig. end                         :: 958320
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP028201.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20828
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20828
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20828
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10828](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10828
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(44..277)
                     /gene="gerPB"
                     /locus_tag="C7M16_RS04710"
                     /old_locus_tag="C7M16_00923"
     CDS             complement(44..277)
                     /codon_start=1
                     /gene="gerPB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388952.2"
                     /locus_tag="C7M16_RS04710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_00923"
                     /product="spore germination protein GerPB"
                     /protein_id="WP_003233090.1"
                     /transl_table=11
                     /translation="MNFYINQTIQINYLRLESISNSSILQIGSAGSIKSLSNLYNTGSY
                     VEPAPEVSGSGQPLQLQEPDTGSLVPLQPPGR"
     gene            complement(292..513)
                     /gene="gerPA"
                     /locus_tag="C7M16_RS04715"
                     /old_locus_tag="C7M16_00924"
     CDS             complement(292..513)
                     /codon_start=1
                     /gene="gerPA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388953.1"
                     /locus_tag="C7M16_RS04715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_00924"
                     /product="spore germination protein"
                     /protein_id="WP_003233088.1"
                     /transl_table=11
                     /translation="MPAIVGAFKINAIGTSGVVHIGDCITISPQAQVRTFAGAGSFNTG
                     DSLKVMNYQNATNVYDNDAVDQPIVANA"
     misc_feature    complement(527..543)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 23.92"
                     /tool="antismash"
     misc_feature    complement(927..941)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 23.18"
                     /tool="antismash"
     misc_feature    complement(928..943)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 21.96"
                     /tool="antismash"
     gene            complement(937..1107)
                     /gene="yisI"
                     /gene_synonym="pchI"
                     /locus_tag="C7M16_RS04720"
                     /old_locus_tag="C7M16_00925"
     CDS             complement(937..1107)
                     /codon_start=1
                     /gene="yisI"
                     /gene_synonym="pchI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388954.1"
                     /locus_tag="C7M16_RS04720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_00925"
                     /product="aspartyl-phosphate phosphatase YisI"
                     /protein_id="WP_003233086.1"
                     /transl_table=11
                     /translation="MNSKIEEMRITLIETAQKYGMNSKETIQCSQELDILLNTRIKEEM
                     IFGRYLENSRM"
     misc_feature    complement(1190..1210)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 24.84"
                     /tool="antismash"
     gene            complement(1252..2175)
                     /gene="yisJ"
                     /locus_tag="C7M16_RS04725"
                     /old_locus_tag="C7M16_00926"
     CDS             complement(1252..2175)
                     /codon_start=1
                     /gene="yisJ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388955.1"
                     /locus_tag="C7M16_RS04725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_00926"
                     /product="CotH kinase family protein"
                     /protein_id="WP_080529155.1"
                     /transl_table=11
                     /translation="MERVHLFFHREQLKRKGTAKGLFVTDRSVSPILLTQRDRAEKASY
                     EISWEKSLLGERTLFLNAEQDDPSLMRRRLAYCFFDQIGVPAPAASYSFLTINGQPEGI
                     YLNINNHQPASKTSYGVKTADPRVPLSLFNNDSSAFLHEFFILIRTAGDDELAERIKLY
                     LDVKLFFLWLIGNACTNQGFYYTFCLNESGRLYVSPIETRSLAVQEWYDEDPLLTKGKT
                     LSSRLLSIPAFRSQYHTLMKNVLKRSFTIERLSPLINEWHLDICQSAADDPFIKKSPFQ
                     IEKEQTNILREIEERQDFLQAHLARL"
     gene            2330..3235
                     /gene="mblK"
                     /locus_tag="C7M16_RS04730"
                     /old_locus_tag="C7M16_00927"
     CDS             2330..3235
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="mblK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388956.1"
                     /locus_tag="C7M16_RS04730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_00927"
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="WP_003233084.1"
                     /transl_table=11
                     /translation="MKFATGELYNRMFVGLIIDDEKIMDLQKAEKKLFELETIPGSLIE
                     CIAEGDKFVAHARQLAEWAKKPNDELGSFMYSLSEVKLHAPIPKPSKNIICIGKNYRDH
                     AIEMGSEADIPEHPMVFTKSPVTVTGHGDIVKSHEEVTSQLDYEGELAVVIGKSGTRIS
                     KEDAYDHVFGYTIVNDITARDLQKRHKQFFIGKSLDTTCPMGPVLVHKSTIQEPERLKV
                     ETRVNGELRQSGSASDMIFSIPELIETLSKGMTLEAGDIIATGTPSGVGKGFTPPKFLR
                     SGDKIDITIDPIGTLSNQIG"
     misc_feature    3268..3282
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.4"
                     /tool="antismash"
     gene            3351..3707
                     /gene="yisL"
                     /locus_tag="C7M16_RS04735"
                     /old_locus_tag="C7M16_00928"
     CDS             3351..3707
                     /codon_start=1
                     /gene="yisL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388957.1"
                     /locus_tag="C7M16_RS04735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_00928"
                     /product="YisL family protein"
                     /protein_id="WP_160221484.1"
                     /transl_table=11
                     /translation="MTHLHITTWVVALILLFVSYSLYSSGSAKGAKITHMILRLFYILI
                     ILTGAELFVRFANWNGEYAGKMILGIITIGLMEMLLIRKQKEKSTGGLWVGFVIVLLLT
                     VLLGLHLPIGFQLF"
     gene            3875..6559
                     /gene="wprA"
                     /locus_tag="C7M16_RS04740"
                     /old_locus_tag="C7M16_00929"
     CDS             3875..6559
                     /codon_start=1
                     /gene="wprA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388958.1"
                     /locus_tag="C7M16_RS04740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_00929"
                     /product="cell wall-associated protease WprA"
                     /protein_id="WP_160221485.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 5.3e-47, bitscore:
                     158.4, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRRKFSSVVAAVLIFALIFSLFSPGTKAAAAGAIDQAAALENGK
                     EQTGAMKEPEQVKWYKVTPGATDIQKNSHMALTVKSDSVLNVSVYPSKEKALKDETFEM
                     YRSFTAEDGKSEVIFPYAWSGPYYVKVEYLGEEEPEDGGTTEAAAEAKYTIGYKGTKKQ
                     PSDLEEEEACPVEMSVDQKKSGKGILDKLRAIRDEQLSQTAEGKELTSLYYKAAPFIVA
                     KLALNKTARNEIYQDLVTLKPLFDDVSENGASSSHKVTEKDQKAINRLYDKALQSVPSF
                     LKEEIKKQADRLNMKQLQGKTAGAILTENNIAAKSEVQTTKVIFKVKDNKSLSSVHNEM
                     KGFSASAQSKKDISNVKKAKKLFDNLYSFELPKDEKQNGAYTASAKRVKSAAATLSKMS
                     NVEFAEPVQEYKSLANDIQYPYQWPLKNNGENGGVKNADVKYEPANTLLSKRKLNDTLI
                     AVVDTGVDSTLADLKGKVRTDLGHNFVGRNNNAMDDQGHGTHVAGIIAAQSDNGYSMTG
                     LNAKAKIIPVKVLDSAGSGDTEQIALGIKYAADKGAKVINLSLGGGYSRVLEFALKYAA
                     DKNVLIAAASGNDGENALSYPASSKYVMSVGATNRMDMTADFSNYGKGLDISAPGSDIP
                     SLVPNGNVTYMSGTSMATPYAAAAAGLLFAQNPKLKRTEVEDMLKKTADDISFESVDGG
                     EEELYDDYGDPIEIPKTPGVDWHSGYGRLNVMKAVSAADLQLKVNKLESTQTAVRGSAK
                     EGTLIEVMNGKKKLGSAKAGKDNAFKVNIATQKQDQVLYVKATKGDAKTSYKVVVVKGK
                     PSGTPKVNAVKTKDTAVKGKANSKAMIRVKNKSKKVIASAKADAKGTFSVKIKKQKAGT
                     VLYVTAADTDKKESKEAKVVVEK"
     gene            complement(6590..7171)
                     /gene="yisN"
                     /locus_tag="C7M16_RS04745"
                     /old_locus_tag="C7M16_00930"
     CDS             complement(6590..7171)
                     /codon_start=1
                     /gene="yisN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388959.1"
                     /locus_tag="C7M16_RS04745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_00930"
                     /product="DUF2777 domain-containing protein"
                     /protein_id="WP_160221486.1"
                     /transl_table=11
                     /translation="MKKKETAWMKRKQLLYTEERKWEYGTILIEDGICLIENGEGDILL
                     ADSLQHSPIWIHHKGKWEQAGFQDKLVLACGAENISLSGGERIRYEKSVKRPLMALLDS
                     LDDETFIAFLQHLHSFGLSVFDCVYSYNKGVFSNSSAEQGVSFYHFSNDTAQCAMQHHY
                     SSEGTGDRFEWTASNGKRSIMYSAVQRGGK"
     misc_feature    complement(7154..7170)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 21.16"
                     /tool="antismash"
     gene            7317..9161
                     /gene="asnB"
                     /locus_tag="C7M16_RS04750"
                     /old_locus_tag="C7M16_00931"
     CDS             7317..9161
                     /EC_number="6.3.5.4"
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="asnB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388960.2"
                     /locus_tag="C7M16_RS04750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_00931"
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="WP_160221487.1"
                     /sec_met_domain="GATase_7 (E-value: 1.8e-46, bitscore:
                     154.9, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 1.9e-99, bitscore:
                     331.5, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGITGWVDFKKQLVQEKQTMDRMTETLSKRGPDDSNVWGEHHVL
                     FGHKRLAVVDIEGGRQPMACTYKGDTYTIIYNGELYNTENLRKELRARGHQFERTSDTE
                     VLLHSYIEWQEDCVDHLNGIFAFAVWDEKRNLLFAARDRLGVKPFFYTKEGSSFLFGSE
                     IKAILAHPDIKARVDRTGLSEIFGLGPSRTPGTGIFKGIKEIRPAHALTFSKDGLNIWR
                     YWNVESEKHTDSFNDTVANVRSLFQDAVTRQLVSDVPVCTFLSGGLDSSAITAIAAGHF
                     EKEGKAPLHTYSIDYEENDKFFQASAFQPNDDGPWIEKMTEAFGTTHHKCVISQKDLVD
                     HLEEAVLVKDLPGMADVDSSLLWFCREIKKDFVVSLSGECADEIFGGYPWFHTADVESG
                     FPWMRSTEERIKLLSDSWQKKLNLKEYVNAKYEETLAETPLLDGETGVDKARRQLFYLN
                     MLWFMTNLLDRKDRMSMGASLEVRVPFADHRLVEYVWNIPWEMKMHDNREKGILRKALE
                     GILPDDILYRKKSPYPKTHHPEYTKGVSEWLKTIRSQKDSVLHTLLDRKQLDQLLETEG
                     SSFKVPWFGQLMKGPQLIAHLAQIHTWFEAYRIDIDER"
     gene            complement(9290..9769)
                     /gene="bstH"
                     /locus_tag="C7M16_RS04755"
                     /old_locus_tag="C7M16_00932"
     CDS             complement(9290..9769)
                     /codon_start=1
                     /gene="bstH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_054576.1"
                     /locus_tag="C7M16_RS04755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_00932"
                     /product="DinB family protein"
                     /protein_id="WP_160221488.1"
                     /transl_table=11
                     /translation="MIKFFEYNWQVRNQWFTWCHQLTTEELLKNRLGGVENILYTLFHI
                     IDVEYSWIRAIQGKEDIAVQFADYQTLNKVKSLSNTFRTEIIDVLQTHSDQIKDELVSV
                     PWETGVLYTRDEILHHIIAHEIHHIGQLSVWARELKLSPVSASFIGRTLKPIHSY"
     misc_feature    9748..9762
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.73"
                     /tool="antismash"
     gene            10001..10828
                     /gene="farP"
                     /locus_tag="C7M16_RS04760"
                     /old_locus_tag="C7M16_00933"
     CDS             10001..10828
                     /codon_start=1
                     /gene="farP"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388961.1"
                     /locus_tag="C7M16_RS04760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_00933"
                     /product="farnesyl diphosphate phosphatase"
                     /protein_id="WP_160221489.1"
                     /sec_met_domain="phytoene_synt (E-value: 3.6e-31, bitscore:
                     106.3, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 7.8e-36,
                     bitscore: 121.7, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHRSEKMKEIKEAYQQCGQIVGEYAPACFKALSYLPLKQRQASW
                     AVLSFCHTAAASADEKVLPAFEAKADHVYQRTNNGKQHLWKAFDHAYRTFTLESEPFRE
                     FIAAQKEDAKPYDDLDELLMYAYRTGGAAGLMLLPILTRRKQDQLKQAAVSLGLAIQLV
                     RFLSDLGTDQQKNRIPRQVMQQFGYTEADLQKGTVNKAFTMTWEYIAFEAEAYLEECQD
                     ALPLFPQYSQKTVKAALHLHRAVLEKIRAKQHDVFQYHFALTETEVKQILSDI"
     gene            complement(10858..12225)
                     /gene="yisQ"
                     /locus_tag="C7M16_RS04765"
                     /old_locus_tag="C7M16_00934"
     CDS             complement(10858..12225)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene="yisQ"
                     /gene_functions="transport (smcogs) SMCOG1086: MATE efflux
                     family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388962.1"
                     /locus_tag="C7M16_RS04765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_00934"
                     /product="MATE family efflux transporter"
                     /protein_id="WP_003233074.1"
                     /transl_table=11
                     /translation="MKQAVFKSTALKKPADKTFSLFSLTWPIFIEVSLYMFMGNADTLM
                     LSQYSDNSVAAVGVSNQILNLIIVMFSFIATGTTVIISQFLGSRQKKEAMEVAYVSIGA
                     NFFISLAISAVVFFAAVPLLHMMGLSDALMPDAKVFLQVVGGLSFIQALIMTFSAILKS
                     YGYTKDTMFVTIGMNILNIAGNFVVIFGLFGFPVLGVAGVAMSTSIARVIGLIAMIVIV
                     NKRIQLKMSLKKVFHMHKEHLRKLLKIGIPSAGEQLSYNLSQMIVTYFIAIMGAQALTT
                     KVYTQNITMFILLFGTAISQGTQILIGRYIGGKQFDAAYERCMKSLYWALGIAAATSVL
                     MTIFSKDLIGLFTQSPDIIATASLLIAMTIILEPGRSFNVIIINSLRAAGDAKFPVYMA
                     MISMWGIGLPLAYLFGIHLGFGLAGIWISFIADEWVRGILMYRRWRSRIWIQKGMA"
     gene            12349..13212
                     /gene="yisR"
                     /locus_tag="C7M16_RS04770"
                     /old_locus_tag="C7M16_00935"
     CDS             12349..13212
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="yisR"
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388963.1"
                     /locus_tag="C7M16_RS04770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_00935"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_160221971.1"
                     /transl_table=11
                     /translation="MPRILFTVPPFPVFIAAGEGVFKKGETHVKRVFSVFDLIYVKQGT
                     LYITENETSFSVEGGEYILLSPGLEHYGTKGSDEATSYYWLHFDEHRYEFTAKGGSNWS
                     ELQQEKGSFEEPARYGLALPRKGKVQRPQFMAQQFEKLIDYSAENSDLPLRKQILFEEL
                     ILHLQKEAFQIPSAKERVAWEAARYLQEHYKEKTTIKDLSLALHYHQDYVSRCMQQVLG
                     VTPAQYTNRVRMTEAKRLLSSTNDKMGVIAETVGMEDPTYFSKLFKQIEGISPIEYRKI
                     VSRKVQ"
     gene            13230..14243
                     /gene="degA"
                     /gene_synonym="iolQ"
                     /locus_tag="C7M16_RS04775"
                     /old_locus_tag="C7M16_00936"
     CDS             13230..14243
                     /codon_start=1
                     /gene="degA"
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /gene_synonym="iolQ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388964.1"
                     /locus_tag="C7M16_RS04775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_00936"
                     /product="transcriptional regulator DegA"
                     /protein_id="WP_160221490.1"
                     /transl_table=11
                     /translation="MKTTIYDVAKAAGVSITTVSRVINNTGRISDKTRQKVMNVMNEMA
                     YKPNVHAAALTGKRTNMIALVAPDISNPFYGELAKSIEERADELGFQMLICSTDYDPKK
                     ETKYFSVLKQKKVDGIIFATGIESHDSMSALEEIASEQIPIAMISQDKPLLPMDIVVID
                     DVRGGYEAAKHLLSLGHTNIACIIGDGSTTGEKNRIKGFRQAMEEAGVPIDESLIIQTR
                     FSLESGKEEAGKLLDRNAPTAIFAFNDVLACAAIQAARIRGIKVPDDLSIIGFDNTILA
                     EMAAPPLTTVAQPIKEMGRSVIELLAEAIEGKRKAKQKIVLPPELVVRHSTSPLNT"
     misc_feature    14380..14389
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     misc_feature    complement(14400..14411)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.99"
                     /tool="antismash"
     gene            14452..15480
                     /gene="iolX"
                     /gene_synonym="yisS"
                     /locus_tag="C7M16_RS04780"
                     /old_locus_tag="C7M16_00937"
     CDS             14452..15480
                     /codon_start=1
                     /gene="iolX"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="yisS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388965.1"
                     /locus_tag="C7M16_RS04780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_00937"
                     /product="scyllo-inositol 2-dehydrogenase"
                     /protein_id="WP_015715649.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 7.3e-33, bitscore:
                     111.7, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 1.7e-27,
                     bitscore: 93.8, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHQVRCAVLGLGRLGYYHAKNLVTSVPGAKLVCVGDPLKGRAEQ
                     VARELGIEKWSEDPYEVLEDTGIDAVIIVTPTSTHGDMIIKAAENGKQIFVEKPLTLSL
                     EESRAVSEKVQETGVICQVGFMRRFDPAYADAKRRIDAGEIGKPIYYKGFTRDQGAPPA
                     EFIKHSGGIFIDCSIHDYDIARYLLGAEITSVSGHGRILNNPFMEQYGDVDQALTYIEF
                     DSGAAGDVEASRTSPYGHDIRAEVIGTEGSIFIGTLRHQHVTILSAKGSSFDIIPDFQT
                     RFHEAYCLELQHFAECVRDRKTPIVTDIDATINLEVGIAATNSYKSGRPVQLDVKRAYT
                     GM"
     gene            complement(15531..16040)
                     /gene="bstC"
                     /locus_tag="C7M16_RS04785"
                     /old_locus_tag="C7M16_00938"
     CDS             complement(15531..16040)
                     /codon_start=1
                     /gene="bstC"
                     /gene_functions="other (smcogs) SMCOG1250: DinB"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388966.2"
                     /locus_tag="C7M16_RS04785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_00938"
                     /product="DinB family protein"
                     /protein_id="WP_160221491.1"
                     /transl_table=11
                     /translation="MTDAKQFYDYHSWANKKIFTHIENLPAETAYQEVKSVFPSVSDVL
                     LHMCRADYIWLNVLSGVAYQEIIDSAGKLESAQGNMAAIKQHAAELESQYHDFFSRQTD
                     LEQTFTMQHPKLGTLESTYADTILHVVNHGTYHRGNVTAMLRQLGHSGVPTDYMYYLYE
                     KRESKG"
     gene            complement(16090..16750)
                     /gene="yisU"
                     /locus_tag="C7M16_RS04790"
                     /old_locus_tag="C7M16_00939"
                     /pseudo=""
     CDS             complement(16090..16750)
                     /codon_start=1
                     /gene="yisU"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388967.1"
                     /locus_tag="C7M16_RS04790"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_00939"
                     /product="LysE/ArgO family amino acid transporter"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTISLMIEKNVKGVFQHECNHSRNCARVWLNFAAGSAECVYFSAR
                     RVAKAYLAGSPSCHQCFSLRYPVNRISRCGRVCHCAGAACV"
     misc_feature    16716..16731
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 25.99"
                     /tool="antismash"
     gene            16818..18272
                     /gene="yisV"
                     /locus_tag="C7M16_RS04795"
                     /old_locus_tag="C7M16_00940"
     CDS             16818..18272
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (121-462). E-value:
                     5.1e-36. Score: 116.5. Matches aSDomain:
                     nrpspksdomains_C7M16_RS04795_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="yisV"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388968.2"
                     /locus_tag="C7M16_RS04795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_00940"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_160221492.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 3.2e-34, bitscore:
                     116.5, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLSQWQPSRKSDVPLHRQIEQYMKDKILHGEWAVGTKIPSQRTL
                     ADMFQVNRSTVTAAIDELTSQGLLEGRRGGGTKVVNSTWSVLAAEPPLDWSDYVRSGIH
                     RANSSIIQAINQNEPRADIIRLGTGELSPDLVPADTIGRMFQQINLGVLSLGYEQPKGN
                     RKLREAVADHLKGKKIHVSPSAILIVSGALQALQLISIGLLKRDSVILTEKPSYLQSLH
                     VFQSAGMRLRGLPMDDEGVKAGLVSSNRKQYGGQLLYTIPSFHNPTGTVMSEQRRKEII
                     SLSKKEQLPIIEDDAYGDLWFEEKPPQPLKAMDHEGNILYLGTFSKTVSPGLRIGWLAG
                     PEPVIERLADIKMQTDYGSSGLSQWAAAEWLSQGYYEEHLTWVRRKLKERRDAAVHFLE
                     RYAGDIATWRIPAGGFYIWVTFHKNLPVSRFFYGLLKRQVLVNPGYIYDGEDRNSIRLS
                     YSYASLGDLETGIKAAAETARRLMMS"
     aSDomain        17181..18203
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C7M16_RS04795_Aminotran_1_2.1"
                     /evalue="5.10E-36"
                     /label="C7M16_RS04795_Aminotran_1_2.1"
                     /locus_tag="C7M16_RS04795"
                     /protein_end="462"
                     /protein_start="121"
                     /score="116.5"
                     /tool="antismash"
                     /translation="DIIRLGTGELSPDLVPADTIGRMFQQINLGVLSLGYEQPKGNRKL
                     REAVADHLKGKKIHVSPSAILIVSGALQALQLISIGLLKRDSVILTEKPSYLQSLHVFQ
                     SAGMRLRGLPMDDEGVKAGLVSSNRKQYGGQLLYTIPSFHNPTGTVMSEQRRKEIISLS
                     KKEQLPIIEDDAYGDLWFEEKPPQPLKAMDHEGNILYLGTFSKTVSPGLRIGWLAGPEP
                     VIERLADIKMQTDYGSSGLSQWAAAEWLSQGYYEEHLTWVRRKLKERRDAAVHFLERYA
                     GDIATWRIPAGGFYIWVTFHKNLPVSRFFYGLLKRQVLVNPGYIYDGEDRNSIRLSYSY
                     A"
     gene            complement(18280..18918)
                     /gene="yisX"
                     /locus_tag="C7M16_RS04800"
                     /old_locus_tag="C7M16_00941"
     CDS             complement(18280..18918)
                     /codon_start=1
                     /gene="yisX"
                     /gene_functions="other (smcogs) SMCOG1286: Pentapeptide
                     repeat protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388970.1"
                     /locus_tag="C7M16_RS04800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_00941"
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="WP_049140709.1"
                     /transl_table=11
                     /translation="MNKIAIQKPNIPENLQTADFHDAMTQDDVISMHLFEDCTICGKDI
                     ERLCVEKTVFRNVVFIDVSFRHIELTDVIFEKCDLSNADFSGAVIHRTSVKQSKMVGMN
                     VAEATLRNVSFEECHGHFSSFSYSNMKQVRFDHCALMQSECSDTVLQQTHFDGCELEGA
                     SFTGTSLQNMDISTCRFEQLHVSLDKLKGCKIAPEHAIAFARALGAVIV"
     gene            19124..19930
                     /gene="yisY"
                     /locus_tag="C7M16_RS04805"
                     /old_locus_tag="C7M16_00942"
     CDS             19124..19930
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (22-254). E-value:
                     4.7e-35. Score: 113.3. Matches aSDomain:
                     nrpspksdomains_C7M16_RS04805_Abhydrolase_1.1"
                     /codon_start=1
                     /gene="yisY"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388971.1"
                     /locus_tag="C7M16_RS04805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_00942"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_032725375.1"
                     /sec_met_domain="PF00561 (E-value: 1.5e-27, bitscore: 94.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.4e-17, bitscore:
                     62.9, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGHYVKTEEHVTLFVEDIGHGRPIIFLHGWPLNHKMFEYQMNELP
                     KRGFRFIGVDLRGYGQSDRPWEGYDYDTMADDVKAVIYTLQLENAILAGFSMGGAIAIR
                     YMARHEGADVDKLILLSAAAPAFTKRPGYPYGMRKQDIDDMIELFKADRPKTLADLGKQ
                     FFEKKVSPELRQWFLNLMLEASSYGTIHSGIALRDEDLRKELAAIKVPTLILHGRKDKI
                     APFDFAKELKRGIKQSELVPFANSGHGAFYEEKEKINSLIAQFSNS"
     aSDomain        19190..19885
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C7M16_RS04805_Abhydrolase_1.1"
                     /evalue="4.70E-35"
                     /label="C7M16_RS04805_Abhydrolase_1.1"
                     /locus_tag="C7M16_RS04805"
                     /protein_end="254"
                     /protein_start="22"
                     /score="113.3"
                     /tool="antismash"
                     /translation="PIIFLHGWPLNHKMFEYQMNELPKRGFRFIGVDLRGYGQSDRPWE
                     GYDYDTMADDVKAVIYTLQLENAILAGFSMGGAIAIRYMARHEGADVDKLILLSAAAPA
                     FTKRPGYPYGMRKQDIDDMIELFKADRPKTLADLGKQFFEKKVSPELRQWFLNLMLEAS
                     SYGTIHSGIALRDEDLRKELAAIKVPTLILHGRKDKIAPFDFAKELKRGIKQSELVPFA
                     NSGHGAFYEE"
     gene            complement(19958..20557)
                     /gene="cysC"
                     /locus_tag="C7M16_RS04810"
                     /old_locus_tag="C7M16_00943"
     CDS             complement(19958..20557)
                     /EC_number="2.7.1.25"
                     /GO_function="GO:0004020 - adenylylsulfate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0000103 - sulfate assimilation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="cysC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388972.1"
                     /locus_tag="C7M16_RS04810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C7M16_00943"
                     /product="adenylyl-sulfate kinase"
                     /protein_id="WP_003245829.1"
                     /transl_table=11
                     /translation="MTHNPNIIWHPAAISKSDRQSLNGHKSCVLWFTGLSGSGKSVLAN
                     AVDEKLYRKGIQSYVLDGDNIRHGLNKDLGFQTGDRIENIRRIGEVAKLFVDSGQMILT
                     AFISPFREDRDMVRALFPKGEFFEIYVKCPLHVCEQRDPKGLYKKARNGEIKHFTGIDS
                     PYEAPLSPDFIIESDQTSISDGADLIINALQNRGII"
     misc_feature    complement(20551..20561)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     misc_feature    complement(20780..20789)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
ORIGIN
        1 ggaaacagat tgatcataca tgttcttcac ctctttcata tgattaacgg ccaggaggct
       61 ggagcgggac caatgaacct gtgtcgggct cctgcagctg gagcggttgc cctgagccag
      121 aaacttctgg tgccggttct acatagcttc ctgtattata caaatttgac agtgacttga
      181 ttgatccggc gctcccgatt tgcagaatgg aggagttgct gattgattcc agccggagat
      241 agttgatttg aatggtttga ttaatataga agttcatgag cctcactcct tttacgcatt
      301 ggccacgatc ggctgatcaa ccgcatcatt gtcatacaca ttcgtcgcgt tttgataatt
      361 catcaccttg aggctgtcgc cggtattaaa gctgccagca ccggcaaacg ttctgacctg
      421 agcctgagga gaaatcgtaa tgcagtcccc gatgtgaacg actccgctcg taccaatcgc
      481 attaatttta aacgctccga caatggccgg catacgagca catcctttgt tgaaaaatta
      541 aaaaaagaca ggtaaagtga aatgacaatt ctgatttcaa ttgggctatt cacgatagct
      601 tatgacaaac gcacatatgt gtgagagaaa tttaaagggg acatatcggc tcttgatgaa
      661 agcgttttat ttttttcggg ccgttatgtt taaacatggc aaaagaggat gttgggtata
      721 aattgagcgg aaatgcggcg aaggatgccg ctatccgcct agggtgattt ttgtttattt
      781 ctttggtgtt tttgcgtgta gaatgctttt tggagtatgt cgtgctgcgg tattcgattt
      841 ttgggcgggc acattctcgc cctgaggtat atcccagaag tgctgagcaa aaaccggagt
      901 tacatgtggt gtattctaat tgttatagaa aatgatttac atacgggagt tttcaagata
      961 tctcccaaaa atcatttctt ctttaatccg ggtattcagc aggatatcca gctcttggct
     1021 gcattgaatc gtttcttttg aattcatgcc gtatttttgt gcggtttcaa ttagtgtgat
     1081 cctcatttct tcaattttac tgttcattac gctatctcca attctagatt ttattttgat
     1141 ataaatacag gatatcgtta gtataaccta ttttggctca aaaggttgcc tttcgtcaat
     1201 ttgactaaaa aagcgacaat ttttgctgcg gcctttttaa tggagaaagg actaaagtct
     1261 tgctaagtgt gcttgcaaaa agtcctgccg ttcctcaatt tctctaagta tgtttgtctg
     1321 ctccttttcg atctgaaagg ggcttttttt gataaaagga tcatcagcag cactttgaca
     1381 aatgtcaagg tgccattcgt tgatgagagg agataatcgt tcaatagtaa acgaccgctt
     1441 cagcacgttt ttcattaatg tgtgatattg cgaccggaag gcgggaatgg atagaagcct
     1501 tgacgaaagc gtctttcctt ttgtcagaag cgggtcttcg tcataccatt cttgtacggc
     1561 aagcgatctt gtctctatcg gggaaacgta aagccggccg gattcgttta aacaaaatgt
     1621 gtagtaaaag ccttgattgg tgcaggcgtt gccgatcagc cacaaaaaaa acagcttgac
     1681 atccagatac aatttaatcc tttcagccaa ttcgtcatct ccggctgtgc ggatcagtat
     1741 gaaaaattca tgtaagaatg ccgaggaatc attgttaaaa agggacaacg gaacccttgg
     1801 atcggctgtc ttcactccgt aactcgtttt actggctggc tgatggttat tgatgttcaa
     1861 ataaatgcct tcaggctggc cattgatggt cagaaagctg tacgaggcag cgggagcagg
     1921 tacgccgatc tggtcaaaaa aacaataggc gagtctgcgc cgcatcaggg acggatcatc
     1981 ctgttctgca ttcaaaaaaa gtgtcctttc accaagcaga gacttttccc agctgatttc
     2041 ataggatgcc ttttccgctc tgtcacgctg tgtgagaaga atgggagaaa cagatcgatc
     2101 tgttacgaaa agccccttgg cagtaccttt ccttttcagc tgctcccggt gaaaaaataa
     2161 atgcacgcgc tccatattct ttcctccttc tcaaaacgac attcgtatga tatgtagagc
     2221 aagctcgtcc tgaaacgaaa tgaaaacgga aaggagaaaa agggatttca gcattcgaca
     2281 gagaatacat gaaggagcat tctgatttaa aagatgatgg aggaataaca tgaaatttgc
     2341 gacaggggaa ctttacaacc gaatgtttgt cggcctgatc attgacgatg agaaaattat
     2401 ggatttgcag aaggctgaaa aaaaactgtt tgaacttgag acgattccgg gatcgctgat
     2461 tgaatgtatc gcagaagggg ataaattcgt tgcgcatgca aggcagctgg ccgagtgggc
     2521 aaagaaaccg aatgatgagc tgggatcatt tatgtattca ttatctgagg tgaagctcca
     2581 tgcacccatt ccgaagccat caaaaaatat catctgcatc ggcaaaaact atcgggatca
     2641 cgcgattgaa atgggaagcg aggctgatat tccggagcat ccgatggtat ttacaaaatc
     2701 accggtaacg gttacggggc atggtgatat cgtaaagagc catgaagagg ttacctctca
     2761 gcttgattat gagggagaac ttgctgtcgt gatcggaaaa agcgggactc gcatttcaaa
     2821 agaagatgca tatgaccatg ttttcggata tacgattgtg aatgatatca cggcgcgtga
     2881 tctgcaaaaa aggcataagc agttttttat cggaaaaagc ttggatacga catgtccgat
     2941 ggggcccgtg cttgtacata aatcaacgat tcaggagcca gagcgcctca aggttgaaac
     3001 aagagtcaac ggcgagctgc gccaatccgg ttcggcaagc gatatgatct tttccattcc
     3061 ggaattaatt gaaaccctct caaaggggat gacgcttgaa gcgggcgaca ttattgccac
     3121 cggtacgccg tctggtgtcg gcaaggggtt tacgcctcca aaattcttgc ggtcaggtga
     3181 caaaattgat attacaattg atccgatcgg aacgctgtca aaccaaattg gctgaataaa
     3241 actggagggc ggacccggac ccgcccgttt tttctgacaa tcatctttgt ggcagaggac
     3301 aagttcatgg tactataagt ggggtaattt atctgatagg gggaacatat atgacacacc
     3361 tacatattac gacatgggtg gtagcgctga ttctgctttt cgtcagctac tcgctgtatt
     3421 cgtcaggaag tgcaaagggc gcaaaaatca ctcatatgat tctgcggtta ttctatatcc
     3481 ttattatttt gacaggagct gagctgtttg tccgtttcgc caactggaac ggagaatacg
     3541 ccggcaaaat gattctgggc attatcacca tcggcctgat ggaaatgctc ctcatccgca
     3601 agcaaaaaga aaaatcaaca ggaggcctgt gggtcggctt cgtcattgtc cttttgctga
     3661 cagtgctgct cggtctgcat ttgccaattg gttttcaatt gttttaatag aaaaacctat
     3721 gaacccggct ctttgataga gttgggtttt tttatattta tcccctcata ttccaaatca
     3781 tttaaaataa ccttaaaatt ccctgtaagc ggtatctcgt cctatgaaat tatgatacct
     3841 tcaaggagat tcattatttt gcaggaggga taacatgaaa cgcagaaaat tcagctcggt
     3901 tgtggcggca gtgcttattt ttgcactgat tttcagcctt ttttctccgg gaaccaaagc
     3961 tgcagcggcc ggcgcgatcg atcaggcggc tgctctggaa aacggcaaag agcagacagg
     4021 cgccatgaag gagccggaac aggtgaaatg gtacaaagtg accccgggag caacggatat
     4081 tcagaaaaac tcacatatgg cactgaccgt aaagagtgat tcagtactga atgtatctgt
     4141 atatccaagt aaggaaaaag cgcttaaaga tgagacgttt gagatgtacc gttctttcac
     4201 agcggaggat ggaaaaagcg aagtcatttt tccatacgcg tggagcggcc cttactatgt
     4261 aaaagttgaa tacctcggag aagaagaacc agaggacggc ggaacaacag aagcagctgc
     4321 agaagccaag tatacgatcg ggtataaagg caccaaaaaa cagccgtcag atttagaaga
     4381 ggaagaagct tgcccggttg aaatgagtgt cgatcagaag aaatcaggaa aaggcatcct
     4441 ggataaattg agagcgattc gtgatgagca gctgagccaa acagcagaag gcaaagaact
     4501 gacaagcctt tattacaaag cagcaccgtt tatcgttgca aagctcgcac tcaataaaac
     4561 agcaagaaat gaaatctatc aggatcttgt gacattaaag ccgttatttg acgatgtgtc
     4621 agaaaacgga gcatcatctt cgcataaggt cactgaaaag gatcaaaaag caatcaaccg
     4681 gctatatgat aaagctttac aatcagtccc gtcattcctt aaagaggaga taaagaaaca
     4741 agcggaccga ctaaatatga agcagctgca aggcaaaaca gccggagcca ttttaacaga
     4801 aaacaatatt gcagcaaaaa gtgaagttca gacaacaaag gttattttca aggtgaagga
     4861 caataaaagc ctctcatccg tacataatga aatgaagggc ttttctgcaa gcgcgcaatc
     4921 gaaaaaagac atatccaatg tgaaaaaggc aaagaaactg tttgacaatc tgtattcatt
     4981 tgaacttccg aaagacgaga aacagaacgg cgcatatacg gcaagcgcca aaagggtcaa
     5041 aagcgctgct gcgacactat ccaagatgtc caatgtagag tttgcggaac ccgtacagga
     5101 atacaaaagc ctggcaaacg atattcagta cccttatcaa tggccgctta aaaacaacgg
     5161 tgaaaacggc ggtgtcaaaa atgcggatgt gaaatatgag cctgccaaca cattgctgtc
     5221 caaacgcaag cttaacgata cactcattgc agtagtagac acaggcgtag acagcacgct
     5281 tgccgattta aaaggaaaag taagaacaga tctcggacac aattttgtcg gacgaaataa
     5341 caatgcaatg gatgatcagg ggcatgggac gcatgtcgca ggcattattg cggcccaaag
     5401 cgataacggc tattcaatga ctggattgaa tgccaaagca aaaatcatcc ctgtcaaagt
     5461 gcttgattcc gcaggttccg gagatactga acaaattgct ctcggcatca aatatgctgc
     5521 tgacaaagga gcaaaggtga ttaatttaag tttaggcgga ggctacagcc gcgtgcttga
     5581 atttgctttg aagtacgcag ctgacaaaaa tgtcttgatt gccgcagcca gcgggaatga
     5641 tggagaaaat gccttatctt atcctgcatc ttctaaatat gtgatgtcag tcggcgcaac
     5701 gaaccgcatg gatatgaccg ctgatttctc taactatgga aaaggtctgg acatatctgc
     5761 tccagggtct gatatcccga gcttagtgcc gaacggaaat gtcacgtaca tgagcggaac
     5821 gtctatggcg acgccgtatg ctgccgctgc tgcaggattg ctgtttgctc aaaatcctaa
     5881 gctgaaaaga acagaagttg aggatatgtt gaaaaagacg gcagatgata tttcctttga
     5941 aagtgtcgat ggcggagaag aagagttgta tgacgattat ggcgatccga ttgaaattcc
     6001 gaagacacct ggtgtagact ggcattcagg ctacgggcgg ctgaatgtca tgaaggctgt
     6061 cagcgcagct gatttacagc ttaaggtcaa caagctggaa agcactcaaa cagctgtcag
     6121 aggaagcgcg aaggaaggca cacttatcga ggtgatgaac ggcaaaaaga aactcggcag
     6181 cgccaaagcc ggaaaagaca atgcgttcaa ggttaatatc gcgactcaaa aacaggatca
     6241 agtactgtat gtgaaagcaa caaaaggcga tgcgaaaaca tcgtataaag ttgttgtcgt
     6301 caaaggaaaa ccttccggca caccgaaagt aaacgcggtg aaaacgaagg atacggcagt
     6361 aaaagggaag gcaaacagca aagcgatgat cagagtgaaa aacaaatcaa agaaagtcat
     6421 tgcttctgcc aaagctgacg caaaaggaac gttttcggtg aaaatcaaaa aacaaaaagc
     6481 cggaacggtg ctgtacgtca cggctgcgga tacagataaa aaagaaagca aggaagcaaa
     6541 agtggttgtt gaaaagtaac caaaaagcgg tgctcgatgc accgcttttt tatttgcccc
     6601 cccgttggac tgctgaatac ataatggatc gctttccgtt tgaagccgtc cattcaaaac
     6661 ggtctcctgt cccttcgctg ctgtagtgat gctgcatcgc gcattgggcg gtgtcatttg
     6721 aaaagtgata aaaggacaca ccctgctccg ccgaagaatt cgaaaagact cctttattat
     6781 aagaatagac gcaatcgaat accgataagc cgaagctgtg caagtgctgc agaaacgcga
     6841 taaaggtttc gtcgtcaaga gaatccaaaa gcgccatgag cggccgcttg actgatttct
     6901 catagcggat gcgttctccg ccggaaaggg agatgttttc tgcaccgcat gccaaaacca
     6961 acttgtcctg aaagccggct tgctcccact ttcctttatg atggatccag attgggctgt
     7021 gttggagact gtccgccagc agtatatcgc cttctccgtt ttcgattaag cagatgccgt
     7081 cttcaatgag gatggtgccg tattcccact ttcgttcctc tgtatataac aattgtttcc
     7141 gtttcatcca tgctgtctcc tttttcttca ttcctctctt ttctttccaa ttcaagcctg
     7201 tcccatacaa ctcttttatg gacaaatcaa ctatctgtct atagatgcat aaacttacta
     7261 aggtgctgaa agaaacgaaa ttgttacgaa agaaacggga ttggagctga tatcacatgt
     7321 gtggaattac gggttgggtc gattttaaaa agcagctcgt ccaggaaaaa caaacgatgg
     7381 acagaatgac agagactctt tccaaacgag ggcctgatga ttcaaacgtt tggggggagc
     7441 atcatgtttt attcggacat aaaagacttg cggttgttga tattgaaggc ggacgccagc
     7501 cgatggcgtg tacctataaa ggggatacgt acaccattat ttacaatggc gagctttata
     7561 atacggaaaa tttgcgcaaa gaattgcggg cgcggggcca tcaattcgaa cgtacgtcag
     7621 ataccgaggt gcttctgcac agctacatcg agtggcagga agactgtgtc gaccatctca
     7681 atggcatatt cgctttcgct gtgtgggatg aaaagcgtaa tctgctgttt gccgcgagag
     7741 accgtctcgg cgtaaagccg tttttttaca cgaaggaagg ctcttcattt ctcttcgggt
     7801 cggaaatcaa agcaatcctc gcgcaccctg atataaaagc gcgagtggac agaacgggac
     7861 tttctgaaat tttcggtctt ggaccgtcca gaaccccggg cactggcata tttaaaggca
     7921 taaaagaaat ccgcccggct catgcgctga cattttccaa agacggactt aatatttggc
     7981 gttattggaa tgttgaaagc gaaaaacata cggacagttt taatgacacg gttgccaatg
     8041 tcagatcgtt atttcaggac gcggtgacgc ggcagcttgt gtcggatgtg cctgtttgca
     8101 cattcctatc aggcggtctg gactcaagcg cgattacagc gattgcggcg ggccattttg
     8161 aaaaggaagg aaaagcaccg cttcatactt attcgattga ttacgaagag aacgataaat
     8221 tttttcaagc aagcgctttt cagccgaatg atgacggacc atggattgaa aaaatgacag
     8281 aggctttcgg cacaacgcac cacaaatgcg tcatcagcca aaaagatctc gttgatcatt
     8341 tggaggaagc tgtactggtc aaagacttgc cgggaatggc ggatgtcgac tcatccctgc
     8401 tgtggttttg ccgggaaatc aaaaaggact ttgtcgtcag cctatcggga gagtgcgcgg
     8461 atgagatttt cggcgggtac ccgtggtttc atacggcaga tgttgagtct ggctttccat
     8521 ggatgagatc aacggaggag cggatcaagc tgctttctga ctcatggcag aaaaaattga
     8581 atctgaaaga atacgtaaat gccaaatatg aagaaacctt ggcagaaacg ccattattag
     8641 atggtgaaac gggtgtggat aaagcaagaa gacagctgtt ctatttaaat atgctttggt
     8701 ttatgacgaa ccttttggat cggaaggatc gcatgagcat gggggcgagc ctggaagtgc
     8761 gggtgccgtt cgccgatcac cggcttgtgg aatatgtttg gaatattccg tgggaaatga
     8821 aaatgcatga taatcgggaa aaaggcattt tgcgcaaagc gcttgaaggt attttgcctg
     8881 atgacattct gtatcgcaaa aaaagcccgt atccgaaaac ccatcatccg gaatatacaa
     8941 aaggcgtcag cgaatggctg aaaacgatca gaagccaaaa ggactccgtg ctccatacct
     9001 tgctggacag aaaacaatta gatcagcttt tagaaacgga aggctcctcc ttcaaggtgc
     9061 cgtggttcgg gcagctcatg aaggggcctc agctaatcgc ccatcttgct caaattcata
     9121 catggtttga agcgtatcgc attgatattg acgagaggta ggttcaatgc aaatgtgatt
     9181 aaaatccaga gatgtataga tttaaataag aaggatagat gagcagggaa atatatgctc
     9241 tatctatcct tttttgtaca acgcactatc gaattgcccc cgcattcctt caataagaat
     9301 gaataggttt taatgttctg ccgataaaac tagctgatac cgggcttaac tttaattccc
     9361 tagcccatac agaaagttga ccaatatggt gaatttcgtg agcgatgata tggtgtaata
     9421 tttcatctcg cgtatataaa acacctgtct cccaaggaac gcttacaagt tcatctttta
     9481 tttgatctga atgtgtttgt aaaacatcaa ttatttcagt tcggaatgta tttgagagag
     9541 atttcacttt attgagtgtt tgataatcag cgaactgaac agcgatatct tcttttcctt
     9601 ggatagcacg aatccaacta tattccacat caataatatg aaaaagggta tataaaatat
     9661 tctctactcc gccaagacgg tttttaagta attcttcagt ggttagttga tgacaccaag
     9721 taaaccattg atttctaacc tgccagttat attcaaaaaa ttttatcact gaactcactc
     9781 caatactatc atgtatcata acaattagcc cttttttccg tgattcctct attattgaag
     9841 tgatgattga gaaatgttta cattctacct gttgtatggc attaaaaata ataatgtata
     9901 tctcgtcgat gatgctgtac gtcttgttac ttttacaaag taagaatcgg cattttcttc
     9961 atatacaatt aggaaaaaac atactagact tgaagaagca gtgatacata ggagtgagaa
    10021 aatgaaagag ataaaagaag cttaccagca atgcggacag attgttggcg aatacgcgcc
    10081 agcctgtttc aaagcattat catatctccc gctaaagcaa agacaagcct cttgggcagt
    10141 attgtcgttt tgccacacgg cggcggccag tgcagacgaa aaggtattgc ccgcatttga
    10201 agctaaagct gatcatgttt accaaaggac aaataacggt aaacaacatc tatggaaggc
    10261 ttttgatcat gcgtatcgga cctttacatt ggaaagcgaa ccttttcggg agtttattgc
    10321 cgcacaaaaa gaagacgcca agccgtatga tgaccttgat gaactgctca tgtacgcata
    10381 tcggacgggc ggtgctgccg gattgatgct gctgccgata ctgacacgcc gaaaacaaga
    10441 tcagctcaaa caagcagccg tctctctcgg cttggccata cagctggttc gcttcttaag
    10501 tgatcttggc acagatcagc aaaaaaaccg cattccccgt caggtaatgc agcaattcgg
    10561 ctatacagag gctgatctcc aaaaaggcac cgtaaataaa gcgttcacaa tgacgtggga
    10621 gtatatcgct tttgaagcag aagcctacct tgaagagtgt caggatgcct tgccgctatt
    10681 tccgcagtat tctcaaaaaa cggtgaaagc cgctcttcat ttgcaccggg ctgttttaga
    10741 aaaaatccgg gcgaagcagc acgatgtatt tcaatatcac ttcgctctca cagagaccga
    10801 agtgaagcag attctgtctg atatctaaaa aacacccggc cttgattgag ccgggtgtta
    10861 cgccatacct ttttgaatcc agatacgtga gcgccatctt ctgtacatta agattccccg
    10921 gacccattca tccgcgataa aagaaatcca aatgccggca agaccgaaac cgaggtggat
    10981 gccgaaaaga taagcaagcg ggaggccgat gccccacatt gaaatcattg ccatgtaaac
    11041 cgggaatttc gcatcccccg cagcccgcag agagttaatg ataatgacat taaacgagcg
    11101 gcctggttca agaataatgg tcatggcaat caataggctt gcagttgcta taatgtcagg
    11161 gctttgtgtg aagagtccga tcaggtcttt tgaaaagatc gtcatcaaaa cagaggtagc
    11221 cgcagcaatt ccgagtgccc aatataagct cttcatgcag cgctcataag cggcatcaaa
    11281 ttgtttgccg ccgatataac ggccgattaa gatttgtgta ccctggctga tcgcagtgcc
    11341 gaacagcaaa ataaacatcg taatattttg cgtatacact tttgttgtca acgcctgcgc
    11401 gcccatgatg gcgataaaat acgtgacaat catttgcgaa aggttgtatg aaagctgctc
    11461 tcccgcagaa ggaatgccga ttttcagcag cttgcgcaaa tgctctttat gcatatgaaa
    11521 gacttttttc agcgacatct tcagctggat gcgtttgttg acaatcacaa tcatcgcgat
    11581 taatccgatg acgcgggcga tagatgtgga catggccaca ccggcaacgc cgagaacagg
    11641 aaagccgaac aaaccgaaaa tcacaacaaa gtttccggca atgtttaaaa tgttcatgcc
    11701 gatagtgaca aacattgtat cttttgtgta gccgtagctt tttaagatcg cgctgaatgt
    11761 catgattaaa gcctgaataa aggacagacc tccgacaact tgtaaaaaga ctttcgcatc
    11821 aggcatcagt gcgtctgata atcccatcat atgaagcaga gggacagccg cgaaaaagac
    11881 gacggcgctg atggccaggc tgatgaagaa gttggcgccg attgacacat aagcgacttc
    11941 catggcttct ttcttttgcc gtgagcctag aaattgtgaa atgataacgg tcgttcctgt
    12001 tgcgataaag ctgaacatca cgataattaa atttaaaatc tggttgctga cgccgactgc
    12061 tgccacgctg ttatccgagt attggctgag catcagtgta tcggcattac ccataaacat
    12121 atataatgag acctcaataa agatcggcca agtaagcgaa aataatgaga acgttttgtc
    12181 agcgggtttt ttcaaagcag ttgatttgaa gacagcttgt ttcatagtgt ctaacccctt
    12241 tcgtaaataa aatcaacgtt ttaaagtgta cctccatttc cttataataa aaagggatag
    12301 aaacgatact tcttgtaaaa atccgactta aaaaggagga tgattcaaat gccccgcatc
    12361 ctgtttacag tcccgccttt tccggtattt attgcagctg gggaaggggt ttttaaaaaa
    12421 ggagaaaccc atgtgaaacg tgtattctcc gtgtttgatc tgatatatgt caaacaggga
    12481 acgttatata taacggaaaa tgaaacatcg ttttctgttg aaggcggcga gtacatcttg
    12541 ctttctcccg gtcttgaaca ctacgggacg aagggcagtg atgaagcaac ctcctactat
    12601 tggcttcact tcgatgaaca ccgatatgaa tttacggcaa agggaggcag caactggtct
    12661 gagcttcagc aggaaaaagg gagtttcgaa gagccggccc gctacggatt ggccttgccg
    12721 agaaaaggca aggtgcagcg cccgcagttt atggcgcagc agtttgaaaa gctgatcgat
    12781 tactccgcgg aaaactctga tttgccgctc agaaagcaaa ttttatttga ggagctgata
    12841 ctgcatcttc aaaaagaagc gttccaaata ccgtctgcga aagagcgggt agcctgggag
    12901 gcggcccggt acttacagga gcactataag gaaaagacga caatcaagga tctgtcgctc
    12961 gcccttcact atcatcagga ttatgtgagc cgctgcatgc agcaggtgct cggcgtaact
    13021 ccggcacaat acacgaaccg ggtgagaatg acggaagcga agcgtctttt atcctctaca
    13081 aatgataaaa tgggcgttat tgcggaaacg gtcggaatgg aagatccgac atacttttca
    13141 aaactcttta agcagataga aggcatttca ccaattgaat accggaaaat tgtcagccgg
    13201 aaagttcaat aaccagacga gggatgaaca tgaaaacaac aatttacgat gtggcaaagg
    13261 cggcgggtgt ctcgatcaca actgtgtccc gtgtgataaa caatacgggg agaatcagcg
    13321 ataaaacacg gcagaaggtc atgaatgtca tgaatgaaat ggcatacaag cccaatgttc
    13381 acgccgcggc gttaacggga aaacgaacga atatgattgc tctcgtggcg cctgatattt
    13441 caaatccgtt ttacggcgaa ctggccaaaa gcattgagga aagagcggat gagctcggtt
    13501 ttcaaatgtt gatttgcagc accgattacg atccgaaaaa agaaacaaag tatttttctg
    13561 tgctgaaaca gaaaaaggtg gatggcatta tttttgcaac agggattgaa agccatgaca
    13621 gtatgtctgc tttggaggaa atcgccagtg aacaaattcc gattgccatg atttctcagg
    13681 ataagccgct tcttccgatg gatattgttg tgatagatga cgttcgtggc ggatatgagg
    13741 ctgccaagca tcttctgtca ctcggccaca cgaacatcgc ctgcattatt ggagacgggt
    13801 caacgacagg cgaaaaaaat agaatcaaag gcttccgtca ggcgatggag gaagcgggcg
    13861 tgcccattga tgaatcactt atcatccaga cgcggttttc cttggaaagc ggcaaggaag
    13921 aagcgggaaa attgctcgac agaaacgctc cgactgctat ttttgccttc aacgacgtat
    13981 tggcttgtgc cgccatacaa gctgcgagaa taagaggcat aaaagtgccg gatgatcttt
    14041 ctatcattgg ttttgataat acgatactcg cagaaatggc ggctccgccc ctgacaaccg
    14101 tagcccagcc gataaaagag atggggcgga gcgtcatcga actgctggca gaagcaatag
    14161 agggaaaacg aaaggcgaaa caaaaaatag tgctcccgcc tgagcttgta gtcagacatt
    14221 ctacatcacc gctcaacaca tgagcccgct aatgagcggg ttttttcatt atgacagttg
    14281 aagccaaaaa aacatattgc gtgtaaacca aaggcagtgt aaaatgaaac catcttttga
    14341 gaaagcgctt gcgcaaaatg gcagagcgga tagaaccgct gtttttttag ctgttaagag
    14401 aaagcgcttt cccaaagcga gcccgaaatg agataaagga gaggatggga cgtggaacat
    14461 caagtaaggt gcgcagtatt gggattagga aggctcggtt attatcatgc gaaaaatctc
    14521 gtcaccagtg tgccgggggc aaagctggtt tgtgtcggtg atccgttaaa agggagagcg
    14581 gagcaggttg ccagagaact cggtatcgaa aaatggtcag aggacccgta tgaagtgtta
    14641 gaagataccg gcattgacgc tgtcattatc gtaacgccga caagcacaca tggtgatatg
    14701 atcatcaaag ctgccgagaa cggcaaacag atctttgttg aaaaaccgct gacattaagc
    14761 cttgaggaat ctagagcagt ttctgaaaaa gtgcaggaga caggtgtcat ctgccaagtc
    14821 ggctttatga gacggttcga tccagcatac gcagatgcca aacggcggat cgacgctgga
    14881 gaaatcggca aacctatcta ttataaaggc tttacgcgcg accaaggcgc gcctcccgca
    14941 gaatttatca aacacagcgg tgggattttt attgactgtt ccatccatga ctatgatatt
    15001 gcccgttatt tgctaggggc ggaaattact tctgtttcag gacacggcag gattctgaac
    15061 aatccgttta tggagcagta cggcgatgtg gatcaggcgc tgacgtatat tgaatttgac
    15121 tccggcgcag cgggggacgt cgaggcaagc agaacctctc catatggaca tgacattcgg
    15181 gcggaggtga tcgggacaga gggcagtatt ttcataggaa cattgagaca tcaacatgtg
    15241 accatcctat cggctaaagg gagcagtttt gatatcattc cagactttca aactcgtttt
    15301 catgaagcct actgcttgga gcttcagcat tttgccgagt gtgtccggga tcgaaaaaca
    15361 ccgattgtga cagatatcga tgcgacgatc aatttagaag tgggcatcgc ggcgaccaat
    15421 tcctataaga gcggcaggcc cgtacagctt gatgtgaagc gcgcttatac aggtatgtaa
    15481 aagctaatgt gttgcatttg aggctttccg caaaaaaaag caaggacatt ttagcccttg
    15541 ctttctcttt tctcatataa atagtacata taatcagtag gtacgcctga atggcccagc
    15601 tgtctcagca tggcggttac gtttcctctg tggtaagtgc cgtgattgac gacatgcagg
    15661 atggtgtctg cataggttga ttccagtgta cctagtttcg gatgctgcat tgtgaaggtc
    15721 tgttctaagt ccgtctggcg gctgaagaaa tcatgatact gtgactccag ctcggcagcg
    15781 tgctgtttaa tcgctgccat attaccttgc gcggactcta atttgcctgc gctgtctata
    15841 atctcttggt aggccactcc cgaaagaaca ttcagccaaa tgtagtcagc cctgcacata
    15901 tgaagcagca cgtcgctgac agaaggaaat acgctcttta cttcttgata ggcagtttcc
    15961 gccggcaggt tttcgatatg ggtaaatatt ttcttgtttg cccaagaatg atagtcataa
    16021 aactgttttg catcagtcat cagcatgccc ccttttctaa gaaattcgtt tttttcatct
    16081 gtttctcctt caattgcaaa agagtgacac cccaaaatat cctgccgctg cccacataac
    16141 cgctgcagag catttgttta cgatcagcat aagcctgccg ctcgtatcta tcgtctgaaa
    16201 caaccggccc gctattgcaa ggctgataaa ccaaatccaa gacacagcga tgcaggcggc
    16261 cataaagagc catttctcaa gccccgaata ttgaagagag ctcgtgccga tgacgccgat
    16321 cgtgtccaga atggcatgcg ggtttaaaag agaaacagca gccgcaaacg cagcttgctt
    16381 ttttggtgtg aacgtatgtt tctcgttttg gcttgtgttc ggacggctgt tccaagtcac
    16441 ccagcccata tagagcaaaa ataaaaatcc gccggccatc atgactgtct caaacacagg
    16501 cagctcctgc acaatgacag acacgcccgc aacggctaat acgattaaca gggtatcgca
    16561 gactgaagca ctgatgacag ctgggagagc ccgccaaata tgcttttgcc acgcgccttg
    16621 ctgaaaaata aacacattct gcactcccag cggcaaaatt aagccaaacg cgagcacaat
    16681 tccgtgaatg attgcattca tgctgaaaaa ctcccttcac atttttttca atcataagag
    16741 agattgtcac taaagtctcc agccatttgg ttgggttagg aaccagccaa atgtataatg
    16801 tgtaaaaaag ggggggcatg accttgtcgc aatggcagcc aagccgaaag tcggatgttc
    16861 cgctgcatcg gcagatcgaa caatatatga aagacaagat tcttcacgga gagtgggctg
    16921 tagggacgaa aatcccctca cagagaacgc tggccgacat gtttcaagtc aaccgcagca
    16981 cagtcacagc agccatagat gaactcacgt ctcaaggctt gttagaggga agaagaggcg
    17041 gcggtacgaa ggttgtaaac agtacttgga gcgtgctggc ggctgagcct ccgcttgatt
    17101 ggagcgatta cgtccgttcg ggcattcatc gcgccaattc ttccatcatt caagctatta
    17161 atcagaacga accaagagcg gatatcatca gattaggaac tggagaactt tcaccggatc
    17221 ttgtgcctgc tgacacaatt ggacggatgt ttcagcaaat caatctgggc gtcctgtctt
    17281 taggatatga gcagccgaaa ggaaaccgta aactgcggga ggcagtggcc gaccatttaa
    17341 aaggaaagaa gatccatgtg tcaccgtctg caattttaat tgtgtccggt gcacttcagg
    17401 cacttcagct catctcaatt ggacttttaa aacgagattc tgtcattttg acggagaagc
    17461 cgtcctacct tcaatccttg catgtatttc aatcagctgg gatgcggctt cgcggcttgc
    17521 cgatggatga tgaaggggtc aaagcggggc ttgtttcttc taatcgaaaa caatatggag
    17581 gacagctgct ttacacgatt ccgtcgtttc ataatccgac aggcacagtc atgtcagagc
    17641 agcgaaggaa agagatcatc agcctgtcaa aaaaagagca gctgcccatc attgaggatg
    17701 atgcgtacgg tgatttatgg tttgaagaaa aacctccgca gccgttgaaa gcaatggatc
    17761 atgagggcaa tattctgtat ctgggcacgt tttcaaaaac ggttagcccc ggtctgcgaa
    17821 tcggctggct tgccggtccg gagccggtta ttgaaaggct ggcggacatt aaaatgcaga
    17881 cagactacgg atcaagcggc ctgtcccagt gggcggctgc cgagtggctg tcacaggggt
    17941 attatgaaga gcatctgact tgggtacgca ggaagcttaa agaaaggaga gacgccgccg
    18001 ttcattttct cgagcggtat gccggggaca ttgccacgtg gcggattccc gcaggcggct
    18061 tttatatttg ggtgacattt cacaaaaacc tgcctgtcag ccgtttcttt tatggattgc
    18121 tgaaacggca ggtgcttgtg aatcccggct acatttatga cggtgaagac cgaaacagca
    18181 tcaggctgtc atattcctat gcatctcttg gagatttgga aactggcatt aaagcggcag
    18241 ctgaaacagc acgccgcctg atgatgtcct aagctttggt tatacgatga cagctcccag
    18301 tgccctggcg aaggcaatcg catgctcagg tgcgattttg cagcctttca atttgtcgag
    18361 ggagacatga agctgttcaa aacggcatgt gctgatgtcc atgttttgaa gggacgtgcc
    18421 ggtaaagctg gcgccttcca attcgcatcc gtcaaagtgt gtctgctgga gcaccgtatc
    18481 gctgcattca ctttgcataa gagcacagtg atcaaatcga acttgtttca tatttgaata
    18541 cgaaaatgag ctgaaatgtc cgtggcattc ctcgaatgaa acattccgca gcgttgcttc
    18601 cgccacattc attccaacca tttttgactg cttaactgaa gttctgtgaa tgacagcccc
    18661 gctgaaatcg gcgtttgata aatcgcactt ttcaaagatc acatcggtca gttcaatatg
    18721 ccgaaaagac acatcgataa agacgacatt tctgaatacc gttttttcaa cacagagtct
    18781 ttcgatatct ttgccgcaga tggtacaatc ttcaaacaaa tgcatgctga ttacatcatc
    18841 ctgcgtcatg gcatcatgaa aatctgcggt ttgcaggttt tctggtatgt ttggtttttg
    18901 aattgcgatt ttattcatgt gatgacatcc tttgctgccc gaaaaacaga ggcttccggg
    18961 ttcaatttaa tagatcgtta aggaaattga tacatatagt aaatcgtgaa gagccttttc
    19021 ttggtacagc agcccgcttg ttttgtaagc ataaatggaa agattcctat acgtcaagtc
    19081 gtttacaggc cgaaaaagcc aaagggaaca ggaggaatgc ggaatggggc attacgtcaa
    19141 aaccgaggag catgtgacac tgtttgtaga ggatatcgga catggaaggc cgatcatctt
    19201 tttgcacggg tggccgttga atcataagat gtttgaatat caaatgaatg agcttccgaa
    19261 aaggggattt cgttttatcg gcgttgattt gcggggatat gggcaatctg accgcccttg
    19321 ggaaggctac gattatgaca cgatggccga tgatgtgaaa gcagtcattt atacgctgca
    19381 gcttgagaat gcgattcttg ccggtttttc aatgggcggc gccattgcaa tccgttatat
    19441 ggcaaggcat gaaggagccg atgttgataa gctgatttta ctgtctgcag cagcccctgc
    19501 gtttacaaaa cgcccgggtt atccgtacgg gatgaggaag caggatattg acgatatgat
    19561 tgaattgttc aaagctgatc ggcccaaaac actggctgat ttagggaaac agttttttga
    19621 gaaaaaagtg tctccagagc ttagacagtg gtttctcaat ctgatgctgg aggcttcctc
    19681 ctacgggacg atccactcgg gcatcgcatt aagagacgaa gatctcagaa aggaacttgc
    19741 tgcaatcaag gtgccgacgc tgatcctgca cgggagaaag gataaaattg cgccgtttga
    19801 ttttgcgaaa gagttgaagc gcggcatcaa acagtcggaa ttggttccgt ttgcaaacag
    19861 cgggcacgga gcattttatg aggaaaaaga gaagatcaac agtttgattg cgcagttctc
    19921 caactcataa gaaaaaaccc gacattgatc gggtttttta tataattcct ctgttttgaa
    19981 gtgcgttaat gatgagatca gctccatcgg aaatagaggt ctggtctgac tcaatgatga
    20041 aatcgggtga aagcggcgct tcatacggag aatcgatccc ggtgaaatgt ttgatctctc
    20101 cgtttcgcgc ttttttataa agcccttttg gatcgcgctg ttcacaaaca tgcagcgggc
    20161 acttcacata aatttcgaag aactcacctt taggaaagag cgctctaacc atgtcccgat
    20221 cctctctgaa tggagaaata aaagccgtta aaatcatttg cccgctgtcg acaaacagct
    20281 tcgccacttc cccgatccgg cggatgtttt caatcctgtc accagtctga aatccaaggt
    20341 ctttgtttaa gccgtggcgg atattatcac cgtcaagcac gtagctctga atgcccttgc
    20401 ggtaaagctt ttcatcgact gcattggcca gcaccgattt tccggagccg gacaaacctg
    20461 taaaccaaag gacgcagctt ttgtgtccgt ttaaggactg tctgtcagac tttgagatgg
    20521 cagcgggatg ccaaatgatg ttcggattgt gtgtcattgc aattccccgc tgttttgttt
    20581 gatggcaaca ggctgttggt gaagtccctt gatcaggacg gctgcgacct caggccggct
    20641 gaattcttta ggcggctttt tgccttggcg gagaagctct ctcacttttg tgcctgataa
    20701 gtggatgtgg tctcttgagc tgtgcggaca tgttttggag gtgcccatgt ttccgcattt
    20761 tcggcaataa aagctgtgct caaaaaacat cggcttgatg cccagctctt cctctgtgaa
    20821 tgattgaa
//
