LOCUS       NZ_WTWY01000019        22131 bp    DNA     linear   CON 30-JAN-2024
DEFINITION  Paenibacillus sp. USDA918EY NODE_19_length_127886_cov_244.128959,
            whole genome shotgun sequence.
ACCESSION   NZ_WTWY01000019
VERSION     NZ_WTWY01000019.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus sp. USDA918EY
  ORGANISM  Paenibacillus sp. USDA918EY
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 127886)
  AUTHORS   Keshri,J., Ramirez,R. and Oakley,B.
  TITLE     Draft genome of a novel Paenibacillus isolate from cecum cecum
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 127886)
  AUTHORS   Keshri,J., Ramirez,R. and Oakley,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-DEC-2019) College of Veterinary Medicine, Western
            University of Health Sciences, 2nd Street, Pomona, CA 91766, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: AUG-2019
            Assembly Method                   :: SPAdes v. 3.12.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 442x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/30/2024 05:01:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,271
            CDSs (total)                      :: 6,215
            Genes (coding)                    :: 6,129
            CDSs (with protein)               :: 6,129
            Genes (RNA)                       :: 56
            rRNAs                             :: 2, 3, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 5 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 31 of 86
            Pseudo Genes (incomplete)         :: 67 of 86
            Pseudo Genes (internal stop)      :: 8 of 86
            Pseudo Genes (multiple problems)  :: 19 of 86
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:00:32
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 77717
            Orig. end                         :: 99848
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            WTWY01000019.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22131
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="redox-cofactor"
                     /region_number="1"
                     /rules="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /tool="antismash"
     cand_cluster    1..22131
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(PF04055 and (TIGR04085 or SPASM))
                     and (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /kind="single"
                     /product="redox-cofactor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22131
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12131](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12131
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
     gene            complement(1532..3256)
                     /locus_tag="GQY55_RS26525"
     CDS             complement(1532..3256)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005546210.1"
                     /locus_tag="GQY55_RS26525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sensor histidine kinase"
                     /protein_id="WP_160044927.1"
                     /transl_table=11
                     /translation="MFKLNYYRRIQLSFLLFIIVPIITVSVISFVLIKETMVEKLQLTN
                     ENFLNVMVDEIGKTIDDATFASHFIVNDTSFKKYLKNFADTDRLRSYDDYTNFTEIKGV
                     FSLITSKPLNNNTRMYLVNRKRFIIPSSEDDTTGVNDRLDELYAKINFKQPETLQWLGM
                     DRGDPGKDGTYYIARVIFDSREKQYLSVLIIGINQAYFEKLLKPVGFGKVALLDAKGNL
                     IAGSAELSAPDPSVPASSLRTEVTLDKTNWTLVYEANKEAFTGKISRTFYAGIGGVILF
                     FIIFSISSMYIAKRLHRPIQKLQRVVRQFGMGNLDVRLEVKGRNDIAELSQTLNTMLDQ
                     LQRLVHDIEREQEQKRVMELEALFMQIRPHFLINTLNSIKCSLILQKDRLHSGIIDSLM
                     SLLRAYMKFNEPTSLRDECELMRHYIDIMKIRNDIPVRLEVELDPEIASWTMPKLMLQP
                     LIENAIVHGLVDHPDAQITIRATKSRGFITIEIEDNGDGIEEKRRLMLNERLQSCDSGP
                     DDPYDRVGLINVAQRLRLSFGSEATIALMPNAERGITAVLHIPDHEIRSLLPGRDAS"
     gene            complement(3355..4482)
                     /locus_tag="GQY55_RS26530"
     CDS             complement(3355..4482)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009672149.1"
                     /locus_tag="GQY55_RS26530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="WP_160044928.1"
                     /transl_table=11
                     /translation="MWTQAIEDAVAKTLRNIERFGDKFPHVSLNGTYGLNDNDDWTDGF
                     WSGMLWLCYEYSGNERFRQAAEATVASFRKRMQEHVVLDHHDIGFLYSLSSKAQWIVSR
                     DESARQLTLQAADALMKRWREPGGYIQAWGRKDDAKEAGRIIIDCLLNLPLLYWASEQT
                     GDPVYRNAAAAQAEKSRRYLVRGDDSSYHTFFFNPETGEPIGGATHQGYSNGSTWTRGQ
                     AWGVYGFALSYRYTKNPLFLESSKRLARYFLNHLPEDHVAYWDFNAPVHADTYRDSSAS
                     AIVAAGLLELISHLDEQDPDRSYFQDMLLKSMTSLVERYATIGEEDAEGLLKRGSYYVH
                     GGISPDDYMIWGDYFYLEALMRMEKGLTGYWYERE"
     gene            complement(4705..5043)
                     /locus_tag="GQY55_RS26535"
     CDS             complement(4705..5043)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006675933.1"
                     /locus_tag="GQY55_RS26535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="zf-TFIIB domain-containing protein"
                     /protein_id="WP_160044929.1"
                     /transl_table=11
                     /translation="MKCPICEDSRMKEVEKNGILIDICPTCKGVWLDRGELDKLMANVR
                     EERPQYNEWYYGDSGDHHAPKEHRQPPGHHYAPPKQHCPEYDKHGHSSYPYKKKKKSVL
                     DVFGDLFD"
     gene            5246..6982
                     /locus_tag="GQY55_RS26540"
     CDS             5246..6982
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024753.4"
                     /locus_tag="GQY55_RS26540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PQQ-binding-like beta-propeller repeat protein"
                     /protein_id="WP_160044930.1"
                     /transl_table=11
                     /translation="MKTTYFKIGIAILSASVVISGCGTSTNKTTPSEPAPATPSKSTPP
                     AAPAKVTGTSFKNFGTYGFDLKNTRHVPYKEVTAENVKDLGVIWSADLKALDKDVKNGN
                     QCYPVVVDGVVYITTAGNQVFAFDAVTGGQIWHWKPSAEQAANFSKAGIIANRGVAVGE
                     GKVFMLTVDNHIVSLDQKTGKLIKMVPISDSVKGVTLENGYYETTAPVYYKGNIYIGSS
                     GGDNGIRGFVNAYKASDLTPAWDTPFWTVPPKGQGWLANSKFQGGGAVWNPPAIDEETG
                     IMYFAVGNPAPDFYGESRPGANPHTDSVVAVDAATGKLIWAKQEISHDLWDYDAAASPM
                     ILDATVKGKKQKIVVQGGKSGQWYAWDAKTGKVIWDGIPFAKIAHPKPTPEGVTVYPGV
                     LGGENYAPETYDPKTNYVLIPGIEQGAVIKSAKSQDEASTPNAPGAAAFGTSELAPSND
                     VPYGTITAMDVNTGKKAYQIKTKDPMRGGFTSTATGLAFYGELDGKINALDIKSGKVIW
                     TFQTTGDSVQAAPAIFTVDDKQYMAFTTGGTTPKVFVFGLGGDKTQGQAGTAEDTNAHQ
                     SK"
     gene            7037..8188
                     /locus_tag="GQY55_RS26545"
     CDS             7037..8188
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GQY55_RS26545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="carboxypeptidase-like regulatory
                     domain-containing protein"
                     /protein_id="WP_236575883.1"
                     /transl_table=11
                     /translation="MKKGAQTPTMKQLYRISMSLLLAVTLAGCAGHSSRHATEALPSSP
                     GTKHDVRLEIDQPVFPIKQWKSDGSHMTSVKGKLLIDDRPVANGMLHPSNTATHVMTGK
                     DGSFKNTLDQSLLSDIKVNVTSLDQATVSGKRLTEDMTKSLQSASATVSVYYPIRVTHV
                     EDSPQDDSQVRVHGQVIPGKGDVVSFFQVDKYRMGGVVKDADGKPVENAVVWFDRDKGE
                     GFGKSTPTDRNGNYSIYYWPEDEDTHLSVTVGTKRYTLPEGRVFKMPEQTSVEIDITLP
                     KKGTVIDDKPPNLVSVTSAGAMYTGVLVGLNLPKEVPYTATIPDKQGRFVITVSKKIWE
                     QKPAFFETTASKFVEGSLTTGDSLPPHYFQPAEEDPKNITPMM"
     gene            complement(8268..8717)
                     /locus_tag="GQY55_RS26550"
     CDS             complement(8268..8717)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF041742.1"
                     /locus_tag="GQY55_RS26550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="WGxxGxxG family protein"
                     /protein_id="WP_160044932.1"
                     /transl_table=11
                     /translation="MKRHIKSGFMAAALSLMLTVPAYAHTATEDGGNGGMGNGMGTVGT
                     KAYDGSRYRINEVGTTSNYDVSVYGTGTGSQYWNTNNQMIDTSRIQTNNYTGYGTNTLN
                     GNTDNRLRAASTPTDRGGWNWGWLGLLGLIGLAGMWGRNPGRERR"
     misc_feature    8852..8868
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 21.15"
                     /tool="antismash"
     misc_feature    9059..9068
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            9081..9998
                     /gene="pqqB"
                     /locus_tag="GQY55_RS26560"
     CDS             9081..9998
                     /codon_start=1
                     /gene="pqqB"
                     /inference="COORDINATES: protein motif:HMM:NF003523.0"
                     /locus_tag="GQY55_RS26560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqB"
                     /protein_id="WP_160044934.1"
                     /transl_table=11
                     /translation="MFVKVLGSAAGGGFPQWNCNCPNCRGVRADRRIYRARTHNSLAVS
                     DDGKAWVLLNATPDIHAQIVSHAELQPGGKVRGTPIFAVLLTDAELDHTIGLLHLRESA
                     EIEVYAASPVLRALEGPFPIRQMLGPYAAFTWSEVKLDESFPLFGGRLIIHPFYLGGKP
                     PRYAAVPDKKEPGPLSPWVIGYRIEDQRTGGSVVYAPGVESWTDELDRHSENADCILMD
                     GTFWQSDELNTLGISELKASDMGHLPIAGPGGSLERLANLSAGRKIYVHINNTNPILHE
                     DSSEYRCLRALGIEVGYDGLELEV"
     gene            10001..10711
                     /gene="pqqC"
                     /locus_tag="GQY55_RS26565"
     CDS             10001..10711
                     /EC_number="1.3.3.11"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR02111"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010283697.1"
                     /locus_tag="GQY55_RS26565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyrroloquinoline-quinone synthase PqqC"
                     /protein_id="WP_236575884.1"
                     /sec_met_domain="TIGR02111 (E-value: 2.5e-102, bitscore:
                     334.2, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNYLLSNEELTMRLKEVGELRYHDKHPYHIRMHEGKLSPEQLRA
                     WVANRFYYQKNIPVKDAIILSKLPTKEDRRQWIQRIMDHDGTAEHEGGIEAWIRLGEAV
                     GIPREEMLDERHVLPAVRFAVDAYVNFCRHKPWLEAVASSLTELFAPILISHRIAVFER
                     LYPWIRPEGLEYFKARLHQAPRDADHGLELVLRECRDRRDQDQAIAALHFKCDVLWAIL
                     DALSLAYPDAENGR"
     gene            10708..10986
                     /gene="pqqD"
                     /locus_tag="GQY55_RS26570"
     CDS             10708..10986
                     /GO_function="GO:0048038 - quinone binding [Evidence IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: Thurincin_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03859.1"
                     /locus_tag="GQY55_RS26570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyrroloquinoline quinone biosynthesis peptide
                     chaperone PqqD"
                     /protein_id="WP_160044935.1"
                     /sec_met_domain="PqqD_RRE (E-value: 5.1e-26, bitscore:
                     83.3, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.9e-17, bitscore: 56.3,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Thurincin_rSAM_RRE (E-value: 1.5e-08,
                     bitscore: 27.5, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMRWELSEQIRLRNPARLKFDKARQTDLLLLPERVVRLNPTAGAI
                     LWLCDGERTVGQIIEELESKYNQSDLEADVLDFLAQAADRGWVEPWK"
     aSDomain        10723..10974
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_GQY55_RS26570_PqqD_RRE.1"
                     /evalue="1.20E-26"
                     /identifier="RREFam006.1"
                     /label="GQY55_RS26570"
                     /locus_tag="GQY55_RS26570"
                     /protein_end="89"
                     /protein_start="5"
                     /score="83.3"
                     /tool="antismash"
                     /translation="LSEQIRLRNPARLKFDKARQTDLLLLPERVVRLNPTAGAILWLCD
                     GERTVGQIIEELESKYNQSDLEADVLDFLAQAADRGWVE"
     aSDomain        10801..10965
                     /aSDomain="Thurincin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a thurincin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_GQY55_RS26570_Thurincin_rSAM_RRE.1"
                     /evalue="3.60E-09"
                     /identifier="RREFam019.1"
                     /label="GQY55_RS26570"
                     /locus_tag="GQY55_RS26570"
                     /protein_end="86"
                     /protein_start="31"
                     /score="27.5"
                     /tool="antismash"
                     /translation="PERVVRLNPTAGAILWLCDGERTVGQIIEELESKYNQSDLEADVL
                     DFLAQAADRG"
     gene            10977..12131
                     /gene="pqqE"
                     /locus_tag="GQY55_RS26575"
     CDS             10977..12131
                     /GO_process="GO:0018149 - peptide cross-linking [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010494345.1"
                     /locus_tag="GQY55_RS26575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqE"
                     /protein_id="WP_236575885.1"
                     /sec_met_domain="PTHR43273 (E-value: 8.1e-33, bitscore:
                     106.7, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.5e-26, bitscore: 86.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 4.1e-10, bitscore: 33.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 3.5e-11, bitscore: 36.5,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 3.1e-12, bitscore:
                     39.7, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEINIPYALTAELTHRCPLHCVYCSNPIELQKRERELTTPDWINI
                     LEEAADLGIVQVHLTGGEPLLRPDVDRIIKRARELDLYVNLITSGVGVTEKRIRQLAHA
                     GIDSIQLSVQAPTAELGDAIAGSFAHEYKKRTAAWIREAGLPLHMNVVLHRQNIHAVEE
                     MIELCVSWGAERLELANAQYYGWALLNRQHLLPTKAQLAAAEEAYARAKARYGRQIELI
                     WVIPDYYEDFPKPCMGGWSSISMTVTPDGRVLPCMAASGIQTMKFESVKEKSLKWIWEE
                     SPSFNAYRGFDWMVEPCRSCEHRFRDFGGCRCQAFLLTGDSQQADPVCSRSPHHGIITG
                     IISSINDTNTEDHERTDSGADPLFPFYSYRGRPTLNGKTSLEQP"
     gene            complement(12315..12566)
                     /locus_tag="GQY55_RS26580"
     CDS             complement(12315..12566)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GQY55_RS26580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_160044936.1"
                     /transl_table=11
                     /translation="MGKIHLKSSVKGAITGASMTGGWLLADLLLPEPWGDVALFAAMAV
                     LNIGIGWKIGKMFERQEAERGVAEAVETKAAAGLESHS"
     misc_feature    complement(12844..12859)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.84"
                     /tool="antismash"
     gene            complement(12847..13668)
                     /locus_tag="GQY55_RS26585"
     CDS             complement(12847..13668)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017813987.1"
                     /locus_tag="GQY55_RS26585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_160044937.1"
                     /transl_table=11
                     /translation="MRRKILITGAAGRIGSCLAEGLRSSNRYDVIATDVNADPGGGIIK
                     LDMTDAPAVEAALQGVDTVLHFGWAKDEGDFLGKVLPVNVAGAYHVYEGARKGGVARVI
                     FASSNHATGFCRVGEKVAPLDHRPDSFYGLSKSYIELLGRFYADQYGISSFNIRIGNFP
                     VDDRPHSERAAHIWISRRDMVHLAECCIEADPSIKFLTLYGTSANDGNYYDIGYLTELI
                     GYRPSDNAAEVPAIQTPGEKDMKHDIGEFQGGPNVRMAERCVETSGGERRD"
     gene            complement(13690..13977)
                     /locus_tag="GQY55_RS26590"
     CDS             complement(13690..13977)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009675658.1"
                     /locus_tag="GQY55_RS26590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_160044938.1"
                     /transl_table=11
                     /translation="MREIREADHGYVMVEDGREVAEITFQPIDERTVMIDHTFVSEELR
                     GQRVGDQLVKAVVDWARKEGKRIVPACSFALVQFKRHKDYKDVWHQEEKA"
     gene            14195..15604
                     /locus_tag="GQY55_RS26595"
     CDS             14195..15604
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014195281.1"
                     /locus_tag="GQY55_RS26595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amino acid permease"
                     /protein_id="WP_160044939.1"
                     /transl_table=11
                     /translation="MTRHKLGFWILTALVVGNMVGSGIFMLPRSLSEAASPAGVLLAWA
                     ATGLGVLMLALVFGSLAVRKPELTGGPQIYAKELFREGSLGSLLAGFMSTWGYWVGNIA
                     GFVAVITTFASYLSTFFPVLTSGKVWLSVGGFTLKAGNALTFLVCSLLLWGTHAICLKG
                     IKGAGRLNFIATATKVIGFILFIVIALFTFQNSNIGPFLAPRTNDSGQTIGLLSQVNAA
                     AVATLWAFIGVESAMVFAARARRKQDIRRATIAGLLISIVLYVGISVLTMGLLTQDQLA
                     ASQNPLVDGISAAIGPVYGKLLAGLGLISLLGSTIGWVLLSAEVPFQAAKQGVFLRSFA
                     KENDMGMPKASLWISNALGQLLLLSTVSGSISAAFDFIIYIATLAYLVPYLIASVYHLK
                     LIWTGETYSLRKERVSEGIIGVLAFIYSAWVIVAGTANLKTFLLGLALIVSGILFYPLL
                     LRNRKTNSKTV"
     gene            complement(15686..16369)
                     /locus_tag="GQY55_RS26600"
     CDS             complement(15686..16369)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015735790.1"
                     /locus_tag="GQY55_RS26600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_236575886.1"
                     /transl_table=11
                     /translation="MGQINTQEYAKYLLGLMDEEADGEEIEDVAFYGYFQMYMPSGKGV
                     EATFLPLENAAEYLRRITPIYDMLDPDDFSGDTVPGYFNGKTVHVAEDVLKNYGEHLIR
                     GLKYLLKEHADLDGTEEAASYLDGIEEVVVIAPREIEEHRSHDRYDPIVYEALSDLVSE
                     HTDYDDPVQILNEAYYSINCDYWISYYLQWHRYGLEGDPLAPYFELYRLGYSAVFSGQK
                     LFIGS"
     misc_feature    16711..16726
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.19"
                     /tool="antismash"
     gene            complement(16732..17289)
                     /locus_tag="GQY55_RS26605"
     CDS             complement(16732..17289)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426846.1"
                     /locus_tag="GQY55_RS26605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YdhK family protein"
                     /protein_id="WP_160044940.1"
                     /transl_table=11
                     /translation="MNKVFAFLGIAAMLVLSGCDHAEKAAESAPTEMDMMSMHHSDSGE
                     IPKGLKEAMSPTYHVGEHVVIHAKHMSGMNGATGKVVGAYDTIAYSVTYTPTNGGQPVK
                     NHKWVIQEEIKDAGSKPLDQGTKVILEADHMEGMMGAQATIDTANRTTVYMVDYTPAKG
                     GAPVKNHKWVVERELSERLYKS"
     gene            complement(17407..18267)
                     /locus_tag="GQY55_RS26610"
     CDS             complement(17407..18267)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006640265.1"
                     /locus_tag="GQY55_RS26610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_160044941.1"
                     /transl_table=11
                     /translation="MNQNEKILITGASGKTGSRIAKRLTDLGYAIRTAGRGKSLPNGAN
                     EHVIFDWFDESTHEAALKDVDKLYLVGPIAVMDPSEIVMPFLERALKTGVRRIVLLGSA
                     SIPEEGPVFGKIHRAIRELAPEWAVLRPSYFMQNFVDSHGAQILNDGTIVSATGSGRVG
                     FVDADDIAEVGVRALTDKQPHNTDHIITGPDSLTYAEAGDIIGAAAGRTIRHVNVPTQE
                     LANRFMAFGMPQDYARFLAGMDEDIRLYGKEDLVTDTVERITGRPPKSLKKFAEEHAAN
                     WKTAK"
     gene            complement(18305..19735)
                     /locus_tag="GQY55_RS26615"
     CDS             complement(18305..19735)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013919668.1"
                     /locus_tag="GQY55_RS26615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_160044942.1"
                     /transl_table=11
                     /translation="MNTSRHKGLALMILAVSQLMLALDYTIVFVALPSLGADLGFSANH
                     LQWVVSAYSLVYGGFLLLGGRLSDMVGRRRMFMIAIALFGVGSLIGGLASSQVLLIVAR
                     GLQGLGGALLSPSTLSLIMSNFDEGAERNRAMSIWAAMGGVGLSLGLLLGGILTSYLGW
                     EFTFFVNVPVSLIALILAPSVLVESKAGPGHKHFDALGTISVTGGMILLVYYLIQSPIE
                     GWLSMGTLPFGLISAALFIGFAVIERYAKEPLVPFRLFRNRNLSGAALTAALFSASFGT
                     LYYFLTLYTQNVLHYSAIQSGLSFLPLTISALLGSRLINRMLAAAGTAGTIAIGMALGG
                     IGFILLTQLSDKGTVWGMIPGTVIIGLGQALVFTTMFIAGGTGIEPRDQGVSSAIVSTG
                     QQVGSSVGLAIIMAIISASLGSDLKLETLKPVDLNHAVHMAFTVAFVITLLGIFIAFMT
                     LKQKKRTSKVNKQGISSR"
     misc_feature    complement(19747..19760)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 21.35"
                     /tool="antismash"
     gene            complement(19843..20424)
                     /locus_tag="GQY55_RS26620"
     CDS             complement(19843..20424)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003233859.1"
                     /locus_tag="GQY55_RS26620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_160044943.1"
                     /transl_table=11
                     /translation="MARNKEFDTTLVLHKAMEVFGHYGYEGTSLQTLLDGLGIARQSLY
                     DTYGTKRDLFIKAVKHYVNEKSSGVVAHLEGGESVKKAIAEIFRTIVSVLQDEERRREC
                     MILHSAIDQIPHDPDIAALFEQDRSCLENAFHEALVRAQNQGEISVGKDLHVLARYLYH
                     ARYAMTQAAKLMNDPKELEEIAAVTLSVLD"
     gene            complement(20599..21087)
                     /locus_tag="GQY55_RS26625"
     CDS             complement(20599..21087)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027: isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811927.1"
                     /locus_tag="GQY55_RS26625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="isochorismatase family cysteine hydrolase"
                     /protein_id="WP_160044944.1"
                     /transl_table=11
                     /translation="MKVGFLIIDMQTIHLENLDNKIINRACEYINYVSNVLRRNGHVVV
                     HVQDIEGIDESNKDLFRTIPEIQVDVNDLILNKEHSSAFWKTDLERMLSDQNVELIIIS
                     GFAAEQCVLFTYNGAVERGFKPVMLQNGILSNSPDVIATTYRDRHVISYPVVEYLIQK"
     misc_feature    21209..21218
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 17.48"
                     /tool="antismash"
     gene            complement(21255..21668)
                     /locus_tag="GQY55_RS26630"
     CDS             complement(21255..21668)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006677654.1"
                     /locus_tag="GQY55_RS26630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_236575887.1"
                     /transl_table=11
                     /translation="MDKHFQIGYEPPEAEEYANLRVKAGLSGKDIEASRRGLPNSLFVV
                     TIRIEGELIGMGRVIGDGGCMFHVVDIAVSPEHQGQGLGKRIMSEITAYLDRHATKGAY
                     VSLMADVPADRLYQQYGFEYGAPASVGMYKKYN"
ORIGIN
        1 ttcttgaata ctttggaaaa ataggttcga tccgagtatc caagacccat cgcgagggat
       61 tccagggttt gcccggagct tttcatcatt ttcgccgcga tgcccatctt gtattggtgg
      121 acgtaatccg taaagttgat gccggtcagc cgcttgaaat accgggaaaa gtagcttgaa
      181 ttcaaataca agtaccgcgc catgtcaatc gaagtaatat tgtctgccag atgctggtcg
      241 atgaattgct ggatcatttg caatttcggc tcgcggatcg ccgcggacga ccccttttgc
      301 ttgtgctggg cgataaaggc gagttgtctt tcggcaagct ccatgacatc ttccagagtt
      361 ctggcatcgg caaggtacgc gtatcgggct tcatccgact ttttttccga gaacatcatg
      421 tcaatgccgc gcaggagcat cgtaatctcg cgtacgaaat cgtcgggttc gaaccgcttc
      481 tcttgggcca attgtgccaa gtttgccatg agctcgcgga tgctccgcat atcgtttccc
      541 aagaccgccc tttccagatc cgatttgtat ccatccaaaa ttcgctgcgg cagaggaaaa
      601 aacaattgcc tatgaaggaa ccccatatcc gttgccgtaa attccccgtt cgcgtaaaac
      661 tcgtgtttat gccggatcat ttgatgataa caggagccaa ggtcggccag tccgatttta
      721 tccgtcacgg cggaaacgtt cagccgcaat ttcaaaaacc gttccgcccc gaaccgcagc
      781 tcccgcagaa acgcttgaaa atgggaatat gcgttgccgg ctaaattttg ccggaaattg
      841 tacataacga tcaggtgatc ctgctccaaa aacggcgtga tcccctcgta agaagcggca
      901 agctcgacgg caatattgta aatggcgtag gaaattaacg agacgttgct ctgaacgtac
      961 agctgttcat aagacgagta atgcaaatgc acaatcccca tcatgaacca gggatattcc
     1021 catgaaatcc cgagcccggc ggcatattcc cgcgtcgttt gcggatccac tccgtccaaa
     1081 atgcgctgca gcaacccttg tttgaacaaa tcgctgctat aattggacgt tttctgatac
     1141 aagggcgtca ctttggaatg aagagagcgg atcgactttt gcaggctttg ttcgagctgc
     1201 tcggccgtca gctggtcttt aagcagataa tcgtccgcgt tcagcttcac cgcctgctgg
     1261 gcataatgaa aatcctcatg gcaggttaaa aagatgacgc ggatgtcggg cttcatatgg
     1321 cgaaaagctt ccgcaagctc gatcccgttt ttttgcggca ggccgatgtc cgtcacgacg
     1381 atatccggcc aagtctcttg aaatagatgc agcgctttgg cgctggagta ggtggatccg
     1441 acgatgcgca gccgaagctc atcccaatcg atcatttgct tcagcacctt cagcatcgga
     1501 acgtcatcat caatcaacat cactttaagc attagcttgc atcccttcct ggaagtaatg
     1561 agcggatttc gtggtccgga atgtgaagca cggcggtgat gccccgctcc gcattcggca
     1621 tgagcgcaat cgtggcctcg gaaccgaaag acaaccgcag tctttgggca acgttgatca
     1681 gcccgaccct gtcatacggg tcatccgggc cggaatcgca gctttgcagc cgttcattca
     1741 gcatcagccg acgtttttct tcgatgccgt ccccgttatc ctcgatttcg atggttatga
     1801 agccgcggct ttttgtggcg cgaatcgtta tttgggcgtc cggatgatcc accagcccgt
     1861 gcacgatggc attttcgatt aaaggctgaa gcatcagctt gggcatggtc catgaagcga
     1921 tttccggatc cagctcaacc tcgagcctaa cgggaatgtc gttccggatt ttcataatat
     1981 cgatataatg ccgcatcaat tcgcactcat cccgcaagga cgtcggttcg ttaaatttca
     2041 tgtaagcccg gagcaaactc attaaagagt cgataattcc gctgtgcagc cggtccttct
     2101 gcagaatcaa gctgcatttg atcgaattaa gcgtattgat caaaaaatgg gggcgaattt
     2161 gcataaacag cgcttccagc tccatcaccc gtttctgctc ctgttcccgc tcgatatcgt
     2221 ggaccaggcg ttgaagctga tccagcatcg tgtttaacgt ttggctcagc tcggcgatat
     2281 cgttccgccc ctttacctcc agcctgacgt ccaaattccc catcccgaac tggcggacga
     2341 cgcgctgcag cttctggatc ggcctgtgga gccgtttggc gatatacatc gaagaaatcg
     2401 aaaagatgat gaaaaacaaa atgacgccgc cgattcccgc gtaaaacgtc cgcgatattt
     2461 tcccggtaaa cgcctctttg ttcgcctcgt acaccagggt ccagttcgtt ttgtccagcg
     2521 tcacttccgt acgcaaggac gatgcgggaa cgctcggatc gggagcggaa agctccgcgc
     2581 ttccggcaat gaggtttcct tttgcatcca ataaagcgac cttgccaaac ccgaccggct
     2641 tcaacaactt ttcaaaatac gcctggttaa tcccgataat cagcaccgat aaatactgct
     2701 tttcgcggct gtcaaaaatg actctggcaa tgtagtaggt cccgtctttg cccgggtcgc
     2761 ccctgtccat gccgagccac tgcagggttt ccggctgttt gaaattgatt ttggcataca
     2821 attcgtccag gcggtcgttg actcccgtcg tgtcgtcctc gcttgacgga ataataaagc
     2881 gttttcggtt taccagatac atccgggtat tgttgttcaa cggcttcgac gtaattaagg
     2941 aaaacacgcc tttgatctcc gtaaagttgg tgtaatcgtc atagctgcgt aaacggtccg
     3001 tatccgcaaa gtttttcaaa tattttttga agctcgtatc attcacgata aaatgggatg
     3061 cgaacgtcgc atcgtcaatc gtttttccga tttcgtcgac catgacgttc aaaaagttct
     3121 cgttggtcaa ttgcagcttc tccaccatcg tttccttgat caggacaaaa gaaatcaccg
     3181 agacggtaat gatcggaacg ataataaaca aaaggaatga caattggatc ctgcggtaat
     3241 agttcagctt gaacatgggt gactttctcc tctttcatgc ttctgggatg attatgctac
     3301 ccgtatcgta tcgcgcttac ggccaagttg tcattcattt tatcggcatt ccgctcattc
     3361 gcgttcatac cagtatccgg tcaggccttt ttccatccgc atcaaggctt ccaaatagaa
     3421 gtagtcgccc caaatcatat aatcatccgg cgatatccct ccatggacgt aatacgatcc
     3481 gcgcttcagc agcccttccg catcttcttc gccaatggtg gcataccgct ccaccaagct
     3541 cgtcatggat ttcaggagca tatcctgaaa ataggaacga tccgggtcct gttcatccaa
     3601 atgggagatc agttccagca aacccgccgc cacgatcgcg gaagccgagc tgtcccggta
     3661 ggtgtcggca tggacggggg cattaaaatc ccaataagcg acgtggtctt caggcaggtg
     3721 gttcaggaaa taccgggcaa gtcgtttcga ggattccagg aacagcgggt ttttcgtgta
     3781 ccggtaagat aatgcaaaac cgtacacgcc ccaagcctgc ccccgggtcc aggtcgaacc
     3841 gttcgaatag ccttggtggg tcgctccccc gatcggttcg ccggtttccg gattaaaaaa
     3901 gaacgtatgg taggaactgt catccccccg gacaagataa cgcctggact tctccgcctg
     3961 tgcggccgcc gcattccggt agaccggatc gcccgtctgt tcgctcgccc agtacagaag
     4021 cggaaggttc agcaggcagt cgataatgat ccggcccgct tccttggcgt cgtctttccg
     4081 gccccaagcc tggatgtagc cgccgggctc gcgccaccgt ttcatcagcg catccgcggc
     4141 ttgcagcgtc aattgccggg ccgattcgtc ccggcttacg atccattgcg cttttgagga
     4201 aagcgaatac aaaaatccga tatcatgatg atccagcacc acatgctcct gcatgcgctt
     4261 gcgaaaactt gcgaccgtgg cttcggctgc ttgacggaaa cgttcattcc cggaatattc
     4321 gtagcagagc cacaacatcc cggaccagaa tccgtcggtc caatcatcgt tatcgttcag
     4381 cccataggtt ccgttcaggc tcacatgcgg gaatttatcc ccgaatcgct cgatatttct
     4441 taacgttttg gcaacggcgt cttctatcgc ttgggtccac atttcaagac acatccccta
     4501 tccatttttg tttcaggttt tagaaccatc ataacgaatc ggagttgccg tcatgcgcgt
     4561 aaattttatc tgtggcgtgc aaaattttga cttttttgag gcgctcccct cacgacaaaa
     4621 gcccggatga tcttcaagat catgccgggc tttcggattc attgatcgac tggcgtatgg
     4681 ttggagcggg atgatgatcc ttgtttaatc aaacaagtcc ccaaacacgt ccaatacgct
     4741 ttttttcttt ttcttatacg gatatgagga atggccgtgt ttgtcatact ccgggcagtg
     4801 ctgctttggc ggcgcataat ggtgcccggg tggctgccgg tgttctttag gcgcgtgatg
     4861 atctccggaa tccccataat accattcgtt atattgcggg cgttcttccc ggacgttcgc
     4921 catcagcttg tccagttccc cccggtccag ccatacccct ttacaggttg ggcatatatc
     4981 gatcaggatg ccgttcttct ccacttcctt catgcgcgaa tcttcacaaa tcggacattt
     5041 cattgcaaat tcctccttgg gattcctctt tacggttcat acggctttta gccgaaacgg
     5101 tttctctttt tcgggccgcg tcattcacga gtttccgcag aagtgaatcg tcaaatccat
     5161 gacggcaacg tccggaattt tttttggcat ggatggaaat agtaccataa aaagtatctg
     5221 aataacacaa aaggagattg ctccgatgaa aacaacttac ttcaagatcg gtattgccat
     5281 tttaagcgca agtgttgtga taagcggctg cggtacaagt acgaacaaaa ccaccccttc
     5341 cgagcctgcg ccagcgacgc cgtccaagag cactccgccg gctgcgccgg caaaagtaac
     5401 ggggacttct tttaaaaact tcggcacgta cggctttgat ttgaaaaata cgcgccatgt
     5461 accttataag gaagtgaccg ccgagaacgt caaagatttg ggcgtcattt ggagcgcgga
     5521 tcttaaagcg ttggacaagg acgtcaaaaa cggaaaccaa tgttaccctg tcgtcgtcga
     5581 cggcgtggtt tacattacga cagccggaaa tcaggtgttt gccttcgatg cggtcaccgg
     5641 cggccagatc tggcattgga aaccctccgc ggaacaggcc gcgaacttca gcaaggcggg
     5701 gatcatcgcg aaccgcggag tcgctgtagg cgaaggcaaa gtgttcatgc tcaccgtcga
     5761 caaccatatc gtttctttgg accaaaaaac gggcaagctc atcaaaatgg ttccgatctc
     5821 cgactccgtc aaaggcgtaa ccttggagaa cggttattac gagacgacgg cccccgtgta
     5881 ttataagggg aatatttata tcggcagcag cggcggcgac aacggcatcc gcggcttcgt
     5941 gaacgcgtac aaggcaagcg atttgacgcc ggcgtgggat accccttttt ggacggttcc
     6001 tcccaaaggg caaggctggc tagcaaacag caagttccaa gggggcggag cggtctggaa
     6061 tcctccggcc atcgacgaag agacgggcat catgtacttt gctgtcggca accccgcgcc
     6121 tgacttttac ggcgaatcga gaccgggcgc caatccccat acggattcgg tcgtagccgt
     6181 tgatgccgcc acgggcaaac tgatctgggc gaagcaggaa atcagccatg acctttggga
     6241 ctacgatgcc gccgcctctc cgatgattct ggatgccacc gtcaaaggaa agaaacaaaa
     6301 gattgtcgta caaggcggga aatccggaca atggtatgct tgggatgcga aaaccgggaa
     6361 agtgatctgg gacggcattc ctttcgcaaa gatcgctcat ccgaaaccga cgcccgaagg
     6421 cgtgaccgtt tatccgggcg tgcttggcgg tgaaaactac gcccccgaaa cgtacgatcc
     6481 aaaaaccaat tacgtgctga tcccggggat cgaacaaggc gccgtcatca aatcggcaaa
     6541 aagccaggac gaagcttcga cgcccaatgc gccgggagct gccgcattcg gcacatcgga
     6601 gctggcgcca tccaacgacg ttccttacgg aacgatcacc gcgatggacg taaataccgg
     6661 caaaaaggca taccagatca aaaccaaaga cccgatgcgc ggaggtttta ccagcacggc
     6721 aaccgggctc gcgttctatg gcgagttgga cggaaaaata aacgcgcttg acattaaatc
     6781 gggaaaagtc atttggacct tccaaacgac aggcgatagc gtacaagccg ctccggcgat
     6841 ttttaccgtg gatgacaaac aatatatggc attcaccacc ggcggaacga cgccgaaggt
     6901 attcgtgttc gggcttggcg gagacaaaac gcaggggcaa gcaggcaccg cggaggacac
     6961 gaacgcgcat cagtcaaaat aataaccgat caaggcatct tacggggtaa agctgtttct
     7021 ggcttacccc gttgccatga agaaaggggc acaaacacca acgatgaaac aactctatcg
     7081 aatatccatg tcactcctgt tggccgtaac acttgccggc tgcgccgggc actcatcccg
     7141 gcacgccact gaagcactac cgtcatcacc agggacgaaa cacgacgttc ggcttgaaat
     7201 cgaccagcct gtgttcccga tcaagcaatg gaagtccgac gggtcccaca tgacttccgt
     7261 aaaagggaag ctgctgatcg atgatcggcc ggtggcgaac ggcatgctgc atccaagcaa
     7321 cacggcaact catgtcatga ccggtaagga cggctcgttc aagaacaccc tcgaccaaag
     7381 cctgctatcc gacatcaaag tcaacgtaac ctcgctcgat caagcgaccg tttccggcaa
     7441 acggcttacg gaagatatga caaagtcgct tcaatcggct tccgcaacgg tcagcgttta
     7501 ttatccgatt cgcgttaccc atgtcgaaga ttctccccaa gacgactcgc aggttcgcgt
     7561 tcacgggcag gtcatccccg gcaaaggcga tgtcgtttcc ttttttcaag tcgataaata
     7621 tcgtatggga ggcgtcgtga aggatgcgga cggcaaaccg gtcgaaaatg ccgtcgtctg
     7681 gtttgaccgg gacaaaggcg aagggttcgg aaagtccacg ccgaccgacc ggaacggcaa
     7741 ctattccata tattattggc ctgaggacga ggatacccat ttgtcggtta cggtcgggac
     7801 gaaacgatac acgcttccgg aaggcagagt attcaaaatg ccggaacaga caagcgtgga
     7861 gatcgatatc acgttgccca aaaaaggcac ggtcatcgac gacaaacccc cgaacctggt
     7921 cagcgtaacg tctgcgggag ccatgtacac cggggttctg gtcggattaa acctcccgaa
     7981 agaggttccg tataccgcca cgattccgga caagcaagga cgttttgtca tcacggtttc
     8041 gaaaaaaata tgggagcaga aaccggcgtt tttcgaaacg acggcttcaa aattcgtgga
     8101 gggcagccta actacgggag attcgctccc cccgcattac tttcaacctg ccgaagaaga
     8161 tccgaagaat ataacgccga tgatgtaaac atcgaaaaag ccctgacata ggtcagggct
     8221 tccgcagtat tgagcaaaat tcatttttca tctgttcgcc tgcaaaatta tctgcgctcg
     8281 cgccccgggt ttcggcccca cattcccgct agtccgatca aaccgagcag gccaagccat
     8341 ccccagttcc agccgccccg gtccgttggg gttgaagctg cgcgcaatct gttatccgtg
     8401 ttgccattga gcgtattcgt gccgtatccg gtgtaattat tggtttgaat tctgcttgta
     8461 tcgatcattt ggttattcgt attccagtat tggctgccgg ttcctgttcc ataaacgctg
     8521 acatcataat tcgatgtagt cccgacttcg ttgattctgt aacgggaacc atcgtacgct
     8581 tttgtcccca cggttcccat tccgttgccc atcccgccgt tgccgccgtc ctccgtcgcc
     8641 gtatgggcat aggccggaac cgtcagcatc aaagacaggg ctgcggccat gaagccgctt
     8701 ttgatatgtc ttttcataag gtacctacct tttgcaaatg tggattttat gccttgcgtt
     8761 attgtgccgc atcgcccccg ttcttatgca atgatgaacc cgcctgcagc cgattctgac
     8821 ctggaacacc tcaggcgcgg cacgttggtt attgttatac aatgtcaaaa cgtaacatag
     8881 gatataaaca atgatgctac agtctcttct cttcatgaac aatggaagag catgatctcc
     8941 agggggtgag cgaaatgtgg gttaagccgg agtttgaggt cattgaggta tgtgccgagg
     9001 taaccgcata tgcgtaccaa aagtaagtat cgagaacatg ccggagaaat ccggcatctg
     9061 ttttttgagg aggaaggaac atgtttgtga aggtgctggg atccgcggcg ggaggaggtt
     9121 ttccgcaatg gaactgcaac tgcccgaatt gccgcggcgt gcgggcggat cgtcgcattt
     9181 atcgcgcccg gacgcataac tcactagccg tcagcgatga cggcaaggcg tgggttcttt
     9241 tgaacgccac tccggacatt catgcccaaa tcgtttccca cgccgaactt cagcccggtg
     9301 gcaaggtgcg cggcactccg atcttcgccg tgctgcttac ggatgccgag cttgaccata
     9361 cgatcggact gctgcattta agggaatccg cagaaataga ggtgtatgca gcgtcccctg
     9421 ttttgcgagc tcttgaaggc cccttcccga tccggcaaat gcttgggcct tatgcagcgt
     9481 tcacatggtc tgaagtgaag ctggacgaat cttttccact ttttgggggg agactaatca
     9541 tacacccgtt ttatttgggc ggaaaacctc ccaggtatgc agccgtcccg gataaaaaag
     9601 aacccggccc tctctcccct tgggtgatcg gataccgcat cgaggaccaa cggacggggg
     9661 gcagcgttgt atacgcgccc ggagtggaat catggacgga tgaactggac cggcattcgg
     9721 agaatgccga ctgcattttg atggacggaa ccttttggca atcggatgag cttaacacgt
     9781 tgggcatctc cgaattgaag gcgagtgaca tgggacatct tccgatcgcc ggtccgggcg
     9841 gaagccttga acgcctcgcc aacctatcgg caggccgcaa aatttacgtg cacatcaaca
     9901 acaccaaccc gatacttcac gaagattctt cggaataccg ctgcctaagg gcgctcggaa
     9961 tcgaggttgg ttacgatggt ttggaattgg aggtctaaac gtgagcaact atttgctgtc
    10021 caatgaagaa ttaacgatga ggctgaagga agtcggggag ctacgatacc atgataaaca
    10081 tccttatcat atccgcatgc atgaaggtaa gctgagtccg gaacagcttc gggcttgggt
    10141 agcgaaccgg ttttattacc aaaaaaacat ccccgttaag gacgcgatca tcctgtcgaa
    10201 actgccgacc aaggaagatc ggcgccaatg gattcagcgc attatggacc atgacggaac
    10261 ggcggaacat gagggcggaa tcgaagcctg gatccgtctc ggcgaagccg tcggcattcc
    10321 gagggaggaa atgctcgacg agcgccatgt gctcccggcc gtccgcttcg cggtggatgc
    10381 ctacgtcaac ttctgccgcc acaaaccgtg gctcgaagcc gttgcgtctt cgttgacgga
    10441 gctgtttgcg cccattctca tttcgcaccg gatcgccgtg tttgaacggc tctatccatg
    10501 gattcggccg gaagggctgg agtattttaa agcaaggctg caccaggctc cccgcgacgc
    10561 ggatcacggg ctcgaactcg tattgcgcga atgcagggat cgccgggacc aggatcaagc
    10621 catcgctgcg cttcatttta aatgcgacgt attatgggcc attttggatg cgttaagttt
    10681 ggcttatccg gatgcggaga acggacgatg atgcgttggg agctgtcgga gcaaatcagg
    10741 ctgcgaaacc cggcccggct gaaattcgat aaagcaaggc aaaccgattt gctgcttctt
    10801 ccggaacgcg tcgtgcgcct gaatcccacg gcgggtgcga tcctgtggct gtgcgacggc
    10861 gaacggacgg ttggccagat tatcgaggaa ctggagtcga aatacaatca gtccgatctg
    10921 gaagcggatg ttcttgattt tctggcgcag gcggcggaca gagggtgggt ggaaccttgg
    10981 aaataaacat cccctacgcc cttacggccg aacttacgca tcgctgcccc cttcattgcg
    11041 tttactgctc gaatccgatc gaacttcaaa aaagggaacg cgagcttacg accccggatt
    11101 ggatcaacat attggaagaa gcagcagacc tggggatcgt gcaggtccac ctcacgggcg
    11161 gggaaccgct attgaggccg gatgtggatc ggatcattaa acgggcccgc gaactggacc
    11221 tttatgtcaa tttgatcacg agcggtgtgg gagttacgga aaaacgcatt cggcagcttg
    11281 cgcatgcggg catcgatagc atccaactta gcgttcaagc gccaacggcc gaactcggcg
    11341 atgcgatcgc gggatctttt gcccatgaat acaaaaaaag aaccgcggca tggatccggg
    11401 aggcgggact gcctttacat atgaatgtcg tgctgcacag gcaaaatata catgcagtgg
    11461 aggaaatgat cgagctttgc gtatcatggg gagctgaacg tttggagctt gctaatgccc
    11521 aatactacgg ttgggctcta ttgaaccgtc agcaccttct ccctacgaaa gcgcagttgg
    11581 ccgccgccga ggaagcatat gcgcgcgcca aggcgcgtta cggccggcaa atcgaactga
    11641 tttgggtcat tccggattat tatgaagatt tcccaaagcc ttgcatgggc ggatggagca
    11701 gcatctcgat gaccgtaacg ccggatggaa gggtgttgcc ctgcatggcg gcatccggca
    11761 ttcaaacgat gaaattcgag tccgtgaaag aaaaaagctt aaaatggatt tgggaggaat
    11821 ccccatcctt caatgcatac cgcgggtttg actggatggt tgagccatgc cggagctgcg
    11881 agcaccgttt ccgggatttc gggggatgcc gctgccaggc ctttctattg acaggcgatt
    11941 cgcagcaagc cgatccggta tgcagccggt cccctcacca tggaatcatt accggaatca
    12001 tttcctctat aaacgataca aacaccgaag accatgaacg aacggattcc ggggctgatc
    12061 cgcttttccc cttctattcc tatcgcggca ggccgacgct aaacggaaaa acgtcacttg
    12121 aacagccttg atcgggcaac gtgggcatca ttttgataac gattatgccg agggcagtct
    12181 actgaactgt catgatgaaa aagtaattta tacaaaagat aaggagccga tgactcatca
    12241 acggctcctt atcttttgcc tatttccggg caaatcgaat gttatatttc aacatgaggc
    12301 catcgctccc aatcctagga atgggattca aggccggccg ccgcctttgt ttccaccgct
    12361 tcggccactc ctctttcggc ctcctgcctt tcaaacattt tgccgatttt ccagccgata
    12421 cctatattca gtaccgccat cgccgcgaac aacgcgacgt ccccccacgg ctccggaagc
    12481 agcaggtccg ccagcaacca tccgccggtc atcgaagctc ccgttatggc accttttacg
    12541 gaagatttta agtgaatttt ccccattccc catacctcca ttgataaact ggccttacat
    12601 cgaggctgaa gcttacattt gccgtgtcga tgaatgcgga aacaaaactt gccgagctat
    12661 gccaaatacc ttgtttttcc tttcggcttc tttccagata ccgggtgcat ggctgcatgc
    12721 ctcgaccctt gccgacaaat gtttgcggac ataaaccgtt tttgcttacc tagaccgatt
    12781 atatgttggg gacaaaatcg attatgctct aaaaccaaga agattgtctt gaagtgcatc
    12841 atttgttcaa tctcggcgtt cgccgcccga tgtttcgaca catcgctcag ccatgcggac
    12901 gtttggtcct ccctggaatt cgccgatgtc atgcttcata tctttttctc cgggtgtttg
    12961 gattgccggc acctccgccg cgttatcact tggtcgatag ccgataagtt cggtcaagta
    13021 accgatgtca taataattcc cgtcgttggc ggacgtgccg tacagggtaa gaaactttat
    13081 cgaggggtcg gcctcgatgc agcactccgc caaatgcacc atatcacggc gcgaaatcca
    13141 gatatgcgca gcccgttccg aatgcggacg gtcatcgacc gggaagttcc cgatacgaat
    13201 gttgaaagag gaaatgccgt attgatccgc ataaaagcgg cccagcagtt cgatataact
    13261 tttgctcaat ccgtaaaagc tgtcgggcct atggtctagc ggcgcgacct tttcacccac
    13321 tctgcaaaat cctgtcgcat ggttggagct cgcgaagatc acccttgcga cgcctccttt
    13381 gcgggcgcct tcgtatacgt gataggcccc ggcaacgttt acgggaagaa ccttgccgag
    13441 aaaatccccc tcatcctttg cccagccaaa atgaagcacc gtatccacgc cctgaagcgc
    13501 agcttccacc gccggcgcat ccgtcatgtc cagcttgatg attccgccgc ccgggtccgc
    13561 attgacgtcg gtcgcgatca cgtcgtaccg gtttgatgac cgcaaccctt cagccaggca
    13621 gcttccgatc cggccggctg ctccggtgat cagaattttt cgccgcatgc cttgcccccc
    13681 tttgattgat caagcttttt cttcctgatg ccacacatcc ttgtagtcct tatgccgttt
    13741 aaattgtacc aaagcaaacg aacaagcagg aacgatccgt ttgccttcct tcctggccca
    13801 atccactacg gccttcacga gctgatcgcc gaccctctgc ccacgaagct cttccgagac
    13861 aaaggtatgg tcaatcatca ctgtccgttc atcgatcggc tgaaacgtga tttccgcaac
    13921 ttcccgccca tcttcgacca tgacgtatcc gtggtccgct tcccgtatct ctcgcatggg
    13981 gtttaccctc cttattccat ttatcaacat ctcttgtatt cttccccgtt ccccgataca
    14041 gcgaaacatt cgggagtact tcgcaggaaa aaatcggttc gcctaaaatt tactctggtg
    14101 ctttaccaga agaaagtgta ttattagtac ctgtcagtgt tttttttata tgcgacttaa
    14161 atttccatca tcaatgctaa aggagtttaa catcatgacc agacacaaat taggcttctg
    14221 gatcctgacc gcccttgtgg ttggcaacat ggtcggttca ggcatcttta tgcttccccg
    14281 ttccctgtcg gaagcggcca gcccggccgg tgttcttctg gcatgggccg cgacggggct
    14341 cggcgttctg atgctcgcgc ttgttttcgg cagtctggcg gtccgcaagc ccgagcttac
    14401 cggcggcccc caaatttatg cgaaagagct gttccgcgaa ggatcgcttg gttcccttct
    14461 cgcaggattt atgtcgacct ggggctactg ggtcggcaat atcgccggct ttgtggccgt
    14521 gatcacgacg tttgcgagtt atttgtccac cttttttccc gtgctgacaa gcggcaaggt
    14581 atggctgtcc gtcggcggat tcacgttaaa agccggcaac gcgctgacat tcctcgtctg
    14641 ttcgctgctg ctgtggggca cgcatgccat ttgcctgaaa ggcatcaaag gcgcgggacg
    14701 gttgaatttt attgccacgg cgaccaaagt gatcgggttt atccttttta tcgtcatcgc
    14761 tttattcact ttccagaaca gcaacatcgg tccgtttttg gctccgcgca cgaatgacag
    14821 cggccaaaca atcggtttgc tctcgcaggt gaacgcggcg gccgtcgcaa ccctgtgggc
    14881 tttcatcggc gtggaatccg ccatggtttt cgcggcgcgc gcccgccgga agcaggatat
    14941 tcgccgggcg acgatcgccg gcctgctgat ttccatcgtt ctttatgtcg gaatcagcgt
    15001 cctgacgatg ggcctgctga cgcaggatca gttggcggct tcccagaacc cgctggtgga
    15061 cggcatttcc gccgcgatcg gcccggtcta cggcaagctt ctggccggtc ttggactgat
    15121 cagcttgctc ggctccacga tcggctgggt gctgcttagc gccgaggtgc cgtttcaagc
    15181 ggccaaacaa ggcgtgtttc ttcggtcgtt cgccaaagaa aacgacatgg gcatgccgaa
    15241 agcatcgctt tggatttcga acgcgcttgg acagttgttg cttctgtcta cggtgtcggg
    15301 ctccatctcg gcagcattcg attttatcat ttatatcgct acgcttgctt atttggttcc
    15361 ttatttgatc gcatcggtat atcatcttaa gctgatttgg acgggcgaaa cctactcttt
    15421 acgcaaggaa agagtatccg aagggatcat cggggtactg gctttcattt attcggcatg
    15481 ggtcatcgtg gcgggaaccg cgaacctgaa gacgttcctg cttggactcg cgcttatcgt
    15541 cagcggcatt ctcttttacc cgcttctgct ccggaatcgg aaaaccaaca gcaagaccgt
    15601 ataagccatg tgctgctgat agcggataag gcgtccatct ttcgatgggc gcctttgaat
    15661 gagtatatta ataacgatct ctcaattatg aaccaatgaa cagcttctga ccggagaaaa
    15721 ctgccgaata accaagcctg tacaactcaa aataaggtgc aagcgggtcc ccctccaggc
    15781 cgtatcgatg ccactgcagg tagtaggaaa tccaatagtc gcagttgatc gaataatagg
    15841 cttcatttaa gatctgaacg ggatcatcgt aatcggtatg ttcggacacg aggtcggaaa
    15901 gcgcctcata aacaatagga tcataccgat catgcgagcg gtgttcctcg atctcccttg
    15961 gggcaataac aacgacctct tcgattccgt ccaaatagga cgcggcttct tccgtgccat
    16021 caagatccgc gtgttccttc aacaaatact tgagcccgcg aatcaaatgt tcgccataat
    16081 ttttaagcac gtcttcggct acatgtacgg ttttcccgtt aaaataaccc ggcacagtgt
    16141 ctccgctaaa atcgtccgga tcgagcatat catagatcgg ggtgatccgc cgtaaatact
    16201 cggccgcgtt ttcaagcggc aaaaaggtgg cttccacccc tttcccgctt ggcatgtaca
    16261 tctgaaaata gccataaaac gcgacgtcct caatttcttc gccgtccgct tcctcatcca
    16321 ttagaccaag caaatacttc gcatactcct gagtgttgat ttgccccatc tccttccata
    16381 aatagtaaca actgaccgta gttcacggac tatcgtggtt gttttggctc tatggttgcg
    16441 attgccctat gtattttgcc gctcccggta ttacctggca agcaggctcc ttgcccaact
    16501 tgcactgatt cggcattcgc cctcttgaat ccagcagccg cagcgctgtc ttttcaagta
    16561 taatatgatt caaaacgaaa tgaatagtgc cggcaaaaac cgaatagaca cttcaacccg
    16621 cctccccatc aacgcctcaa aaagcgaaga ccttctgagt atagaaaaaa tcccgtctct
    16681 tcagagacgg gacctcccca ttgtttccct cagaccggct ggtccgggtg cttagctttt
    16741 atacaatctt tcggaaagtt ccctttccac gacccactta tgatttttca ccggggctcc
    16801 gcccttcgca ggcgtgtaat ccaccatata aaccgtcgtc cgattggccg tatcgattgt
    16861 agcctgcgcc cccatcatgc cttccatatg atcggcctca agtattacct tcgtaccttg
    16921 gtccaaaggt ttgctgccgg catctttgat ctcctcctga atgacccact tatggttctt
    16981 taccggctga ccgccgttcg tcggggtata cgttacagag taggctatcg tatcataggc
    17041 ccccacaact ttgcctgtcg ctccgttcat gccggacata tgcttggcgt ggatgaccac
    17101 atgttctccc acatgatagg tcggactcat ggcttctttt aaacctttcg gaatttcgcc
    17161 ggaatcggaa tgatgcatgc tcatcatatc catttccgtt ggggcgcttt ccgctgcctt
    17221 ttcggcatgg tcgcagccgc ttaaaacgag catggccgcg atgcccaaaa aagcgaagac
    17281 tttattcatc gttgtcacac accttttcgt attgaatcga aaccgggaaa cccgggactt
    17341 ttatcatttt tacccaatat tacccggttc ataggcgtgg tggcgaaatg ttctttgatt
    17401 gcttgattat ttggcggttt tccaatttgc ggcatgttct tcggcaaact ttttcaggga
    17461 tttcggcggg cgtccggtga ttcgttccac ggtgtcggtc accagatcct ccttgccata
    17521 aagtctgatg tcctcatcca tccctgcaag aaaacgggcg taatcttgag gcatcccgaa
    17581 tgccataaaa cgattcgcaa gttcttgggt cggcacgttg acgtgacgga tcgtccgccc
    17641 ggccgcggcg ccgatgatgt ctcccgcttc ggcgtaagtc aaagaatcgg gccccgtaat
    17701 gatatgatcc gtattgtgag gctgcttatc ggtcagcgcc ctaacaccga cttcagcaat
    17761 atcgtcggca tctacaaaac cgacccttcc cgatccggtt gccgatacga tggtcccatc
    17821 gttcaaaatt tgcgcgccgt gactgtccac gaaattttgc ataaaatagg acggccgaag
    17881 caccgcccat tccggcgcca gttcacgtat agcccggtgg atcttgccaa aaaccggacc
    17941 ctcttcggga atcgatgcgc tgccgagcaa cacaattctg cgaacgcctg tcttgagcgc
    18001 tctctccaaa aacggcatca cgatttccga aggatccatc acggcaatcg gacctaccaa
    18061 ataaagctta tcaacgtcct tcaaagcagc ctcatgcgtg gattcgtcga accaatcaaa
    18121 gatcacgtgt tcattggcgc cgtttggcaa cgacttgccc cggccggccg ttcgaatggc
    18181 ataacccaaa tccgttaggc gtttggctat ccggctccct gtttttccgc ttgctccagt
    18241 gattaaaatt ttttcatttt gattcatatg gttcgctcct ttttagattg ttcggtccaa
    18301 aatattaacg ggaagagatt ccttgtttat tgaccttgga tgttcgtttt ttctgtttaa
    18361 gcgtcatgaa agcaatgaaa atgcccagca atgttatgac aaaggcaacg gtaaatgcca
    18421 tatgcaccgc atgattcaag tcgaccggct ttaaagtttc cagcttgagg tctgatccca
    18481 ggctcgcgga aatgatggcc ataatgatgg ccaaccctac cgaactgccg acttgctggc
    18541 ctgtcgaaac gatggccgac gacacccctt ggtctcgtgg ttcaataccg gtgccgcccg
    18601 caatgaacat ggtcgtaaac acaagcgctt gccctaagcc gataatgacg gtgccgggaa
    18661 tcattcccca cacggtgccc ttgtcggaaa gttgcgtaag cagaataaag ccgatgccgc
    18721 ccaaagccat gccgatggca atcgtaccgg ccgtgcctgc cgcagccagc atcctgttga
    18781 tgagtctcga acccagaaga gcgctgatcg tgagcggcaa gaagcttaaa ccggactgaa
    18841 tggccgaata gtgcaataca ttctgcgtgt ataaggtaag aaagtaatac agcgttccga
    18901 aggaagccga gaataaggcc gcagttaacg ccgctccgga aagattgcgg ttgcggaata
    18961 atcggaatgg aaccaacggt tctttcgcgt aacgttcaat gacggcaaac ccgatgaaca
    19021 atgctgcgct gatcagtcca aacggcagcg tccccatgct cagccagcct tcaatcggag
    19081 attggatcaa gtaatagacg aggaggatca ttcctccggt gacggatatc gttccgagtg
    19141 cgtcaaaatg tttatgtccg ggtccggctt tgctttccac cagaacggat ggcgcaagga
    19201 tcaaggcgat gagggaaacc ggaacattaa caaaaaaagt gaactcccag ccgagatagc
    19261 tggtcaatat tccgccgagc agcaatccga gggacaggcc cacgcctccc atcgccgccc
    19321 aaatgctcat cgcccggtta cgctccgcgc cttcgtcaaa attggacatg atcagcgaca
    19381 gcgttgacgg cgacagaagc gccccgccga gtccctgcaa ccctctggca acaatgagca
    19441 acacttggga gctcgccaaa ccgccgatga gcgaaccaac gccaaagagc gcaatggcga
    19501 tcataaacat ccgcctccgc cccaccatgt cggacaatct tcctcccaac agcaaaaatc
    19561 cgccgtacac gagcgaatag gcgctgacga cccactgcaa atgattggcc gaaaacccta
    19621 aatccgctcc gagcgaaggc aatgccacaa aaacaatcgt gtaatccaac gccaacatta
    19681 gttgggatac ggcgagaatc ataagcgcca aacctttatg cctgcttgta ttcatgcaaa
    19741 ctctcctttt tataattata gaccaaacag tccgattaat ttagattttt tgaccaatcg
    19801 atccgaaatg gccggatgaa ggaaacgtca aacgacgctt cttcaatcca gcaccgaaag
    19861 cgtaaccgcg gcgatctcct ccaattcctt gggatcgttc attagtttag ccgcttgcgt
    19921 catcgcgtat ctcgcatgat acaaataccg cgccagtaca tgcaggtcct tgccgacgct
    19981 aatctcccct tggttttgag cgcgaaccag cgcttcatgg aacgcatttt ccaaacacga
    20041 ccggtcttgc tcaaacagcg ccgcaatgtc cgggtcatgg gggatttggt cgatggcgct
    20101 gtgcaaaatc atacattccc tgcgccgctc ttcatcctga agcacggaca cgatcgttcg
    20161 aaaaatttcg gcgatcgctt tttttacgga ctccccgcct tccaagtggg ctacgacgcc
    20221 ggatgacttt tcgttaacgt aatgtttgac cgctttgatg aacaaatctc ttttcgtacc
    20281 gtaagtgtcg tacaaacttt ggcgggcgat ccctaatccg tcaagcaagg tttgcaatga
    20341 tgtgccttcg tacccgtaat gtccaaacac ttccatcgct ttatgcagga caagggtcgt
    20401 atcgaattcc ttgtttcttg ccatgtaaat gatacctctt ttctatatct cttcatgcaa
    20461 tcagcaagtc gatcaaactt atcggactgt tcagtctaaa acaatcaaat caaagcctcc
    20521 tttccttcat gaactgaata ttatcatttc cggatcgttc agtcaataat gaatttggag
    20581 gcgtttattt tcccgatttt atttctggat taaatattca acgacggggt aagaaatcac
    20641 atgcctgtcc cggtaggtcg tggcgatcac gtcaggggaa ttgcttaaga ttccattttg
    20701 caacataacc ggtttaaacc ctctttcaac ggctccgttg taagtaaaca atacgcactg
    20761 ttctgcggcg aatccggaaa tgatgatcaa ttctacattt tgatccgata acattcgttc
    20821 caaatccgtc ttccaaaatg cgctcgagtg ttctttgttt agaatcaagt cattaacgtc
    20881 aacctggatt tccggaatgg ttcgaaataa atccttattg gattcgtcga tgccttcaat
    20941 gtcttggaca tgtacgacga catggccgtt ccggcgaagc acattcgaaa catagttgat
    21001 atattcgcaa gcccggttaa tgattttgtt atccaaattc tcaaggtgga tcgtctgcat
    21061 atcgataatt aaaaagccga ctttcattgc ggtcgctcct tccaaaatgt caccttaacg
    21121 tatttgaatc caaaatatgt atcgaaaaaa tatctctgaa gccgatttga catcatcgta
    21181 ccatacgctc tcctgctgca gtcgggagtg attttttata atcatctttt ctcggtcagt
    21241 aatgcaggct cccgtcaatt gtactttttg tacatgccta cggatgccgg ggcgccgtat
    21301 tcgaagccgt actgctgata cagccggtcg gccggcacat cggccatcaa gctgacgtaa
    21361 gcccctttcg tggcatgccg gtccaaatag gccgtaattt ccgacatgat tcgtttaccc
    21421 agcccttggc cttgatgttc aggggacacg gcaatatcca cgacatggaa catgcagccg
    21481 ccgtcgccga tgaccctgcc catgccgatc aattcccctt caatcctgat cgtaacgacg
    21541 aacaaggaat tgggcagccc cctgcgggaa gcttcgatat ccttgccgct gaggcccgcc
    21601 ttaacccgaa ggttggcgta ttcttccgct tcgggaggct cgtaaccgat ttgaaaatgc
    21661 ttatccaccg cgtaacatcc tttccctgag gtcttttggc acatcataaa tcataataca
    21721 atggcaaccc tggcccactc ataacaatgg tcaaaccttt accgttctga aaccgaagtt
    21781 agcagctcga tcatctcgtt ttcctcgcgg cttttggcga tgtcgagcgg ggtttggccg
    21841 ctttggtcca ggagcgatgg attcgccccg tgctgcagga gcacttcgac gacatccagc
    21901 ctttcctctc cgtcggacgc ctgcgcgtga agcggcgtgt tcccgtcatc cgctgccgca
    21961 ttgacgtccg ccccatgccg aatgagcagc gatgcgattt caggatacaa aacgatatgc
    22021 agcggcgtta tgccctcgtc attttttgct tggacatcag ccccgtgatt tattagaaat
    22081 tccaccatga cttcgttgtc cgtcatcact gccgcgtgca aaaccgaaaa c
//
