LOCUS       NZ_CP047144            21347 bp    DNA     linear   CON 30-JAN-2024
DEFINITION  Streptomyces sp. HF10 chromosome, complete genome.
ACCESSION   NZ_CP047144
VERSION     NZ_CP047144.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. HF10
  ORGANISM  Streptomyces sp. HF10
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7814787)
  AUTHORS   Li,J., Ni,J. and Li,Y.
  TITLE     Multiple polyene macrolides produced by antifungal Streptomyces from
            gut of Macrotermes barneyi facilitates the termite-fungus mutualism
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7814787)
  AUTHORS   Li,J., Ni,J. and Li,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-DEC-2019) State Key Laboratory of Microbial
            Technology, Shandong Unversity, 72 Binhai Road, Qingdao, Shandong
            266237, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 10-NOV-2018
            Assembly Method                   :: SPAdes v. NOV-2018
            Assembly Name                     :: SDU_Sthf_5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/30/2024 05:29:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,091
            CDSs (total)                      :: 6,988
            Genes (coding)                    :: 6,640
            CDSs (with protein)               :: 6,640
            Genes (RNA)                       :: 103
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 79
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 356
            CDSs (without protein)            :: 348
            Pseudo Genes (ambiguous residues) :: 0 of 356
            Pseudo Genes (frameshifted)       :: 235 of 356
            Pseudo Genes (incomplete)         :: 154 of 356
            Pseudo Genes (internal stop)      :: 18 of 356
            Pseudo Genes (multiple problems)  :: 53 of 356
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:39:54
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7143274
            Orig. end                         :: 7164621
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP047144.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Jinfeng Ni.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21347
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="nucleoside"
                     /region_number="30"
                     /rules="(LipM or LipV or LipU or TunD or pur6 or pur10 or
                     nikJ or nikO or truD)"
                     /tool="antismash"
     cand_cluster    1..21347
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(LipM or LipV or LipU or TunD or pur6 or
                     pur10 or nikJ or nikO or truD)"
                     /kind="single"
                     /product="nucleoside"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21347
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:11347](+)"
                     /cutoff="20000"
                     /detection_rule="(LipM or LipV or LipU or TunD or pur6 or
                     pur10 or nikJ or nikO or truD)"
                     /neighbourhood="10000"
                     /product="nucleoside"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11347
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(LipM or LipV or LipU or TunD or pur6 or
                     pur10 or nikJ or nikO or truD)"
                     /neighbourhood="10000"
                     /product="nucleoside"
                     /protocluster_number="1"
     gene            complement(709..1365)
                     /locus_tag="GR129_RS31625"
                     /old_locus_tag="GR129_31625"
     CDS             complement(709..1365)
                     /EC_number="1.14.11.-"
                     /GO_function="GO:0008198 - ferrous iron binding [Evidence
                     IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025024.4"
                     /locus_tag="GR129_RS31625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_31625"
                     /product="2OG-Fe(II) oxygenase"
                     /protein_id="WP_159707001.1"
                     /transl_table=11
                     /translation="MNAGVIDLQTPGHRTVQQDPYPWAVLHECFGDQGAAADLAAHFPA
                     GGYTLRAGDAATGKGYSTYNLTLADRGEPAPEVRGLAPQWRSLVATLLGDDYRAWLART
                     MGTDLNGCTAHLRAVRYAQQGWIDPHTDRADKAVTQIWYFNPVWPPEWAGALRVLRSAD
                     PEDVAAEVRPLLGTSVLMRPSANSWHCVTPVAPGAPDRLTLLLHFVRPEPTEGGR"
     gene            complement(1362..2012)
                     /locus_tag="GR129_RS31630"
                     /old_locus_tag="GR129_31630"
     CDS             complement(1362..2012)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025024.4"
                     /locus_tag="GR129_RS31630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_31630"
                     /product="2OG-Fe(II) oxygenase"
                     /protein_id="WP_159707003.1"
                     /transl_table=11
                     /translation="MTPEPHRTEETMLDLDAPVTAHRTPYIWAQADGLLPLPLLERLRG
                     ALPATDLFDRKERAAGGDKAYAMQVLPLVRGGADCAVLDRLDPVWRDLVDALRTPAYLD
                     WVQRAVEVPVTARHAEIGLFVFGTDDHVSCHTDKSGKLASHVIYLNEAWGPDDGGAFEV
                     HTSGSGGTPHATLPPEAPRSVVFARSEHSWHAVEPVRADDGRLRWTIQVELWA"
     gene            complement(2009..2887)
                     /locus_tag="GR129_RS31635"
                     /old_locus_tag="GR129_31635"
     CDS             complement(2009..2887)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (1-177). E-value: 9.6e-08. Score:
                     24.1. Matches aSDomain:
                     nrpspksdomains_GR129_RS31635_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012334.4"
                     /locus_tag="GR129_RS31635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_31635"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_159707005.1"
                     /transl_table=11
                     /translation="MLGGTRGLGRELAREAMRHDCGVVVYGRSAAPAEAPAAEVPEAET
                     LAAEVTAAAVPAARAQPLRARALDLTDPAAVDAVDLAELRGPGPLYLFWVAGEFLKQPL
                     AETAAEDADRLTALLWQGPVRLLRRLLADRLRQPSPPQPLHLVTVASASSWRAREEQSL
                     YCGLKAAQAAFTRALTPELLRADPRNRVTLIQPGAMATPGFHDVLGLTPEELDAFMDPA
                     VVAAHIWQLVNRPEHPARRFLEAHLLRGPADPVTGHAVPRLLLGPQAPEAPPPPDRPHR
                     SGRPLPEAARL"
     aSDomain        complement(2357..2884)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GR129_RS31635_PKS_KR.1"
                     /evalue="9.60E-08"
                     /label="GR129_RS31635_PKS_KR.1"
                     /locus_tag="GR129_RS31635"
                     /protein_end="177"
                     /protein_start="1"
                     /score="24.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="LGGTRGLGRELAREAMRHDCGVVVYGRSAAPAEAPAAEVPEAETL
                     AAEVTAAAVPAARAQPLRARALDLTDPAAVDAVDLAELRGPGPLYLFWVAGEFLKQPLA
                     ETAAEDADRLTALLWQGPVRLLRRLLADRLRQPSPPQPLHLVTVASASSWRAREEQSLY
                     CGLKAAQAAFTRA"
     CDS_motif       complement(2822..2881)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GR129_RS31635_0001"
                     /evalue="2.50E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="GR129_RS31635"
                     /protein_end="22"
                     /protein_start="2"
                     /score="13.7"
                     /tool="antismash"
                     /translation="GGTRGLGRELAREAMRHDCG"
     gene            complement(2920..4146)
                     /locus_tag="GR129_RS31640"
                     /old_locus_tag="GR129_31640"
     CDS             complement(2920..4146)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GR129_RS31640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GR129_31640"
                     /product="hypothetical protein"
                     /protein_id="WP_159707007.1"
                     /transl_table=11
                     /translation="MPSATDSPSATVPGPTAPGAPPAPCAAPRSESFTLGYAFAALHVD
                     SRVPGVRELLPRVLGPAFATTDSGAGAPAGVLRLTVRLRGSEEPTAATVHGLERMPTLL
                     LDGTRQVVLARTPEVVTVLQLAEEDATELLLTAHPGTGEVDLALPDGSPGALRAVARTV
                     KFLVGAQLTAAGLPVFHGSAVARDGEGIVVVGPSGSGKSSLMFLVATRAGWDFVSDDLV
                     FAWAGADGAPRMSGWSNRIGLSVATLSGHPARRRFEEARLRRYDQPIGPLDVDADRPWS
                     RADRVRVYCDIDEFLEVARIGGAAAVRPRGVVVPVAERDRKGWEITVEEPGDLRWRSDF
                     DANIRQLKHVTDFLGLVPRPATAGNGAVGVGAALDAMPVVRARYGRDMLDDVPRFWAEV
                     TEALQRARR"
     gene            complement(4212..5618)
                     /locus_tag="GR129_RS31645"
                     /old_locus_tag="GR129_31645"
     CDS             complement(4212..5618)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012497.4"
                     /locus_tag="GR129_RS31645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_31645"
                     /product="hypothetical protein"
                     /protein_id="WP_159707009.1"
                     /transl_table=11
                     /translation="MASRMVLIAQAVPASSRSAAADLPAVVVHGGGRIGGQVRVAGHKH
                     SMVAAFAATLALGVRATLTGVPQVTERDVLLEQLELLGCTWSVEGDQVVLDATAARPAP
                     LSARLTRKIHGSLYLLPAMLARFGEVEFPGAGGDQLGDFEMGQGRPFLHLLEMLERFGC
                     RFEVSADGSVHGRRDRRRCADVELLDWSDDPRTIAGSRMSSVTKAALLLAAATDGTSRL
                     RHPLVLWSTQDLMSFLGAAGVGVAVDPDGGAVTIRGRGPGHGRAAAQLAPDCLETVTWA
                     ACAVATGGTVEIRTGAPDRMRRMMHHELAALAQLGVQHEWDGDRLTVTGDPGTLRPADL
                     VARNATLSTDALPLYTTVMMRAPGRSSVSDLVWLGRYAYAEHLGRVGVPTSTTGASLTV
                     VGGAPLRPADAPLTPGDTRSGAVALITALAAPGRTEVHGLDHVHRGYADMLGKLTALGA
                     GLTPCPVPAP"
     misc_feature    complement(5744..5759)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.73"
                     /tool="antismash"
     gene            5816..6559
                     /locus_tag="GR129_RS31650"
                     /old_locus_tag="GR129_31650"
     CDS             5816..6559
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024744.4"
                     /locus_tag="GR129_RS31650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_31650"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_159707011.1"
                     /transl_table=11
                     /translation="MADAPALQNLGINFRPVQCPHLRPGHLHRSADLRTLSPEECGRLY
                     GEYGIRAVLDLRSAPERERDGLPATAASGLGLVDHHVPLTGYPHDPIGSPRPGAADYAR
                     YYTGMVRRSSSEDLRALFATVARVAHEPFLLACYCGKDRTGVVTAALMVLAGCDDACVA
                     TEYGRTAEGLIPHVDHFSRLWTGYGHTREDFLARLGQTRQETMLLFLATMRREHGGLVP
                     ALLDRGVSPADLDRIGALLTAGAAA"
     gene            6556..7404
                     /locus_tag="GR129_RS31655"
                     /old_locus_tag="GR129_31655"
     CDS             6556..7404
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GR129_RS31655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GR129_31655"
                     /product="hypothetical protein"
                     /protein_id="WP_159707013.1"
                     /transl_table=11
                     /translation="MSTAAPGATAAPGATAAPRVAAVIGEAAGLGRALTELALRQGVPV
                     FRFGSAEDCAGSPPGAESRLVDLADAAQPWTVDPALPGPALVFWVAGRFLQQPFAELTA
                     ADAEALTRHSLTGPAALLARILAADPHPVHLVTVGSVSAWRARQHQAYYCALRAAQSAL
                     TRNLLPELREHSPDGRATLVELGGLAVPPLPPYPAMDYGTTLDPVHVAELVWRLADTQT
                     EPLTHAVIQRDKRPGAEGSPLLSFHGPVPDPPPHPRPDTLRPVGTHPNREERGEVEQQR
                     T"
     gene            7401..7943
                     /locus_tag="GR129_RS31660"
                     /old_locus_tag="GR129_31660"
     CDS             7401..7943
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016144.4"
                     /locus_tag="GR129_RS31660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_31660"
                     /product="GrpB family protein"
                     /protein_id="WP_159707015.1"
                     /transl_table=11
                     /translation="MSRHPMVITAYDPVWPEAFAVEAARIAAVCPVGTAVEHIGSTAVP
                     GLAAKPVLDVLVGVAALEPEGAACVRALVANGYRYKPDFEAAMPDRRYLTRSTADGVRI
                     ANVHLVRRGDPMWRQTLAFRDALRQDPALRAGYEAAKRAALAAAPEDVHRYNDAKAPFI
                     ARALEALGVAPPRPEQR"
     gene            complement(7990..8664)
                     /locus_tag="GR129_RS31665"
                     /old_locus_tag="GR129_31665"
     CDS             complement(7990..8664)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GR129_RS31665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GR129_31665"
                     /product="hypothetical protein"
                     /protein_id="WP_159707017.1"
                     /transl_table=11
                     /translation="MTADRAGGGPAPERVVLGALAQARRVAVVGCPGSGKTWLATRLAA
                     LTGLPYVGLDDHYFDRAWQVRGPAERWRADHEVLVQGTSWVMDGLHSTTLPDRLHRADA
                     VVWLDYPTRVCVLGYLRRTARWRLTGRAPGYASAADGAVRLPPDATSFLRFILTFRRRR
                     RPALAELLARQGADCPVVRLTRRSQVPGLLEALTASVDSGGQGRPARRDRRDAVAAPDD
                     NR"
     gene            complement(8661..9824)
                     /locus_tag="GR129_RS31670"
                     /old_locus_tag="GR129_31670"
     CDS             complement(8661..9824)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (36-359). E-value:
                     4.5e-37. Score: 119.9. Matches aSDomain:
                     nrpspksdomains_GR129_RS31670_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012382.4"
                     /locus_tag="GR129_RS31670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_31670"
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_159707019.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 5.2e-35, bitscore:
                     119.9, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAASAVRTRPTMLEAVAASPVQALRTYRRRRVPGAVNLASNELR
                     HPVLERLAGEALSDLPAADLAGYPSGTAVTRLLADRLRTSPESLLLVAGSDDAYRLLTE
                     ALGPTLGAAAVTQQLNYQSLPDYARLRGLELLTAPYLPQRHAFDTAELIRLQAARPGRA
                     VVWLSNPNGPTGAVHTPEELENLCATVAAAGNLLVVDEVYRDFQDGPRWAGPARTGHHR
                     HLLRLRSFSKGYGLAGARLGYLHGHPDLISYLARWNTPGPVSVTALHLAAHLLRHGDEV
                     AAVHREVAADRAWFATAADALPGFTALPSQGNFVAVRAGTDQLVRRGLDALAEEGITVR
                     DLRPLGVMGPVLRVGMAQRPVLRRALTALSQAADDQATRDGAGAGRE"
     aSDomain        complement(8748..9716)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GR129_RS31670_Aminotran_1_2.1"
                     /evalue="4.50E-37"
                     /label="GR129_RS31670_Aminotran_1_2.1"
                     /locus_tag="GR129_RS31670"
                     /protein_end="359"
                     /protein_start="36"
                     /score="119.9"
                     /tool="antismash"
                     /translation="VNLASNELRHPVLERLAGEALSDLPAADLAGYPSGTAVTRLLADR
                     LRTSPESLLLVAGSDDAYRLLTEALGPTLGAAAVTQQLNYQSLPDYARLRGLELLTAPY
                     LPQRHAFDTAELIRLQAARPGRAVVWLSNPNGPTGAVHTPEELENLCATVAAAGNLLVV
                     DEVYRDFQDGPRWAGPARTGHHRHLLRLRSFSKGYGLAGARLGYLHGHPDLISYLARWN
                     TPGPVSVTALHLAAHLLRHGDEVAAVHREVAADRAWFATAADALPGFTALPSQGNFVAV
                     RAGTDQLVRRGLDALAEEGITVRDLRPLGVMGPVLRVGMAQR"
     misc_feature    9894..9909
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.95"
                     /tool="antismash"
     misc_feature    9907..9922
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.73"
                     /tool="antismash"
     gene            10001..11347
                     /locus_tag="GR129_RS31675"
                     /old_locus_tag="GR129_31675"
     CDS             10001..11347
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     nucleoside: nikJ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="other (smcogs) SMCOG1277: Radical SAM
                     domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF015983.4"
                     /locus_tag="GR129_RS31675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_31675"
                     /product="radical SAM protein"
                     /protein_id="WP_159707021.1"
                     /sec_met_domain="nikJ (E-value: 1.2e-165, bitscore: 550.2,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.5e-17, bitscore: 62.4,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKILVVWPPHVPGYFNAGHHTPLFEVAEYLRRRPGVERVDALDG
                     GALNVNWKDLGATLYQGRYDVIAMMNDYDAVDGFERFLSYARELSPGAKVITFGRLSAQ
                     NPGHFLRYDLDAVVRSGDVECGVGDYVDAVLAGEPERPLPGVQVRTADGWTAPTAPGRT
                     LEPDEWALPDVREIPYEAYERLYARDDRKFCGIPFRRELVVPIARGCPVGCSYCDVHEI
                     FGLRERRLGVDAVLEYIAAAREAEPSFEYVSFYAPTFTLNRPWTRELCRRLLEQPDRLP
                     WKCTTTVPHLDEKMVQLMGAAGCVRISVGLETLDEDGHGSLPRSKRVHQDRFESLARWC
                     ADAGIELNAFVMVGLPGTSPEGTAATVAFARSLDVRVRPTLYTPLHDLRPTMTTAEVSR
                     YNRHTLTTPTPPELAEQHYSHIFGPESRLTRVQERIPRAAAPVPAPAST"
     gene            11344..12351
                     /locus_tag="GR129_RS31680"
                     /old_locus_tag="GR129_31680"
     CDS             11344..12351
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024871.4"
                     /locus_tag="GR129_RS31680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_31680"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_159707023.1"
                     /transl_table=11
                     /translation="MIRASAAPPEVVPLTRAVWEQALRQDPQAMATQTPGWLDAICAEG
                     PWAEAGRLYRWDDGTRIVLPLVTHTGPPGPGSPELASWPTEWGVGGPLCPDGPPTSAHT
                     AAVLADLADVPGRVRLRIGPLTAGPWAEAVPERAGRTPRTTHVVDLAGPAGAWRQRLHP
                     GARRSMRKAARSGLDVTRGSTAHDLEVFYALYQQSMDRWATRSGEPADQVRRRIEARDP
                     LRKLRTVRDRLGGACSVWTAWYRGEPAASVILLRQGRQAKYWRGAMSQPLAAPTRANHL
                     LHELALQEAADAGCTHYHMGDSHPGGVTRFKESLGARPYPTPAYLLPAAPLTAR"
     gene            12378..13592
                     /locus_tag="GR129_RS31685"
                     /old_locus_tag="GR129_31685"
     CDS             12378..13592
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF026257.4"
                     /locus_tag="GR129_RS31685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_31685"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_159707025.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 6.7e-12, bitscore:
                     44.1, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVMDASPHPDPPHSAERIVQATRDYYGLDQDRPDRLLHRAERSD
                     PKFRLTLLSAYHHAHPGALSASRVHELDEARARLAAYAAVRDRLAQVVPGLSPVKGLAI
                     SACYPAPLLRHQGDLDLHVPDEAGLWRAAQALISDGWQHTDLAVRQVDHAPAHLLTFYR
                     PHGDDLARPLYVELTDVAWLGDGRRSMPRRTLPATAAADGAAREGLPADDVVTSLLFLC
                     LEGLERALGLRDAVDTWLLAVRLTAEDRALLTDLIDRLGLHDGYRRMVAAAGRAGLLAD
                     GGLLPGAPRPRRRRPTLRRPDIAVLNWLQWAGFYRGPSRLRSAVWERLSMRIDAPTAFR
                     GGMWAFGIPAEALGDHARTPALGDTPPALQETAVLRGRRRLSTPLGDFLLVSGPRVPAG
                     ILDAA"
     gene            complement(13901..14464)
                     /locus_tag="GR129_RS31690"
                     /old_locus_tag="GR129_31690"
     CDS             complement(13901..14464)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009191782.1"
                     /locus_tag="GR129_RS31690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_31690"
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="WP_145484253.1"
                     /transl_table=11
                     /translation="MSVRILALVGSLRAGSHNRQLAEAAAKLAPEGAEVVIFEGLADVP
                     FYNEDIDVEGSVPAAAAALRAAAQGADAFLLFSPEYNGTMPAVLKNAIDWLSRPYGAGA
                     FGGKPVAVIGTAFGQFGGVWAQDDTRKSVGIAGGKVIEDIKLSIPGSMTRFAETHPADD
                     AEVAAQLTEVVTRLHGTAAQITAA"
     misc_feature    complement(14453..14468)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.83"
                     /tool="antismash"
     misc_feature    complement(14483..14500)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.51"
                     /tool="antismash"
     gene            14565..15245
                     /locus_tag="GR129_RS31695"
                     /old_locus_tag="GR129_31695"
     CDS             14565..15245
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387335.1"
                     /locus_tag="GR129_RS31695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_31695"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_201300730.1"
                     /transl_table=11
                     /translation="MLYSVVMSSAPQPFPTPQEPSDAPPLLELGTAPEEPCLRADAARN
                     RARLLEAAARLIAEHGVAGVTMEAVAAAAQVGKGTVFRRFGDRTGLLMALLDHSGRRLQ
                     ADFLGGPPPLGPGAPPLERLRAFGIAVLYRSAEQLELQLAAQPEACRRFSHPATQALRT
                     HVTMLLRQIVPDADCELLSQTLLASLDPALIHHLTRQRGMPMARLEAAWVDLVARVTRT
                     QQPV"
     misc_feature    complement(15283..15292)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.19"
                     /tool="antismash"
     gene            15350..16345
                     /locus_tag="GR129_RS31700"
                     /old_locus_tag="GR129_31700"
     CDS             15350..16345
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676462.1"
                     /locus_tag="GR129_RS31700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_31700"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_145484255.1"
                     /transl_table=11
                     /translation="MVQIPNTPTSADVARLAGVSRATVSYVLNNTDAVRISEPTRRRVH
                     EAARELGYVPHAAARSLRAGHSRTVLMPAPAIPVGPLYSAFLNEVHSALGRLDYTVVQY
                     GSVGLPGDEAARAWAELRPVAVLVPGTGIGPRGVAVLKRSGARAVVTLGPERVEGAHAL
                     LMDHDAVGRCAAAHLYERGRRRIGVVVPEEPGLEVYSRPRLDGARQALRGTGASVIGVP
                     LAYTERAAAELAANWPGLDAVFAYNDEYAMLLMRGLQDAGRRIPEDVAVIGADDLMLGR
                     LLRPRLSTVRIELPAGRDLAALVDRAVRDPGGEPEVHRVLGSSVVRREST"
     misc_feature    15710..15712
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(16374..16760)
                     /gene="trxA"
                     /locus_tag="GR129_RS31705"
                     /old_locus_tag="GR129_31705"
     CDS             complement(16374..16760)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="trxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006376459.1"
                     /locus_tag="GR129_RS31705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_31705"
                     /product="thioredoxin"
                     /protein_id="WP_159707027.1"
                     /transl_table=11
                     /translation="MSGTVELTKDNFDQTVTDNDFVLIDFWASWCGPCRQFAPVYEKAA
                     KDNPDLVFGKVDTEAQPELAQAFGIQSIPTLMIVRDRVAVFAQPGALPEAALTDVIGQA
                     RGLDMDEVRKSIAAQEGAEEGQAR"
     misc_feature    16711..16726
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 23.51"
                     /tool="antismash"
     gene            16956..18395
                     /locus_tag="GR129_RS31710"
                     /old_locus_tag="GR129_31710"
     CDS             16956..18395
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004979724.1"
                     /locus_tag="GR129_RS31710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_31710"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_159707029.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.3e-46, bitscore:
                     157.0, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTETTESETIAYDVVVLGAGPVGENVADRTRAAGLTTAIVESELV
                     GGECSYWACMPSKALLRPVIAQADGRRLPGLAAAVQGPLDTPAVLERRDNFTSHWQDDG
                     QVDWVEGIGADLYRGHGRLAGPRTVTVTVSDGGVTTLTARHAVVVCTGTRAQLPDLPGL
                     AEVRPWTSREATSADTAPGRLLVVGGGVVATEMATAWAALGSRVTLLVRGKGLLGRMEP
                     FAGELVAEALTEAGVDVRTGASVTSVTRENGTVVALTRTGERFEADEILFATGRVPQTD
                     DIGLDTVGLEPGSWLETDDTLRVAGTDWLYAAGDVNHRALLTHQGKYQARIAGAAIGAR
                     AAGTPLLDGPWGPHAATADHEAVPQVVFTDPEAAAVGLSLAEAEEAGHRVRAVDVEFSS
                     VAGAALYGDGYKGRARMVVDLEDEILRGVTFVGPGVGELIHSATIAVAAHVPISRLWHV
                     VPSYPTLSEVWLRLLEAYRDN"
     gene            complement(18404..19048)
                     /locus_tag="GR129_RS31715"
                     /old_locus_tag="GR129_31715"
     CDS             complement(18404..19048)
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /GO_process="GO:0018206 - peptidyl-methionine modification
                     [Evidence IEA]"
                     /GO_process="GO:0031365 - N-terminal protein amino acid
                     modification [Evidence IEA]"
                     /GO_process="GO:0043686 - co-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676465.1"
                     /locus_tag="GR129_RS31715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_31715"
                     /product="peptide deformylase"
                     /protein_id="WP_159707031.1"
                     /transl_table=11
                     /translation="MASDRDHAPLAERVEELLAAGGPLPIVAAGRPVLRRPTEAYDGQL
                     GPALLARFVEALRLTMHAAPGVGLAAPQVGVELRIAVLEDPAPVPDEIAAVRGRRPQPF
                     RVLVNPVYEPVGTTRAAFFEGCLSVPGWQAVVARHTEVRLRAEDECGRPVDEVFTGWPA
                     RIVQHETDHLDGTLYLDRAEPRSLSTNEAVAALWSQPTPSTAATALGFELP"
     gene            complement(19264..19611)
                     /locus_tag="GR129_RS31720"
                     /old_locus_tag="GR129_31720"
     CDS             complement(19264..19611)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012999005.1"
                     /locus_tag="GR129_RS31720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_31720"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_145484262.1"
                     /transl_table=11
                     /translation="METTYYGHGTPAERWERAQAFFAAKDYAGAARVLAALVEEVPEQT
                     GPRLLLARAYYHSAQLRRAEDQLRTIVERDPVEHYARLMLGRTLERQSRHAEAERHLRI
                     AAALAGEPARG"
     misc_feature    complement(19600..19615)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.61"
                     /tool="antismash"
     misc_feature    19604..19619
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.21"
                     /tool="antismash"
     gene            complement(19765..20889)
                     /locus_tag="GR129_RS31725"
                     /old_locus_tag="GR129_31725"
     CDS             complement(19765..20889)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009720567.1"
                     /locus_tag="GR129_RS31725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_31725"
                     /product="XdhC/CoxI family protein"
                     /protein_id="WP_159707033.1"
                     /transl_table=11
                     /translation="MRDIAEGLSAWSASGKRFAVATVVRTWRSAPRQAGSSLAVAEDGE
                     VIGSVSGGCVEGAVYELASEVLESGEPALVTYGVSDDDALAVGLTCGGIIEILVRPAGA
                     GRFPGLPGVLEAMGAGRPVAVVSPLPDEGGGAEPDPTAAPAGQLIVTPSGGRGTLGDAR
                     LDASVVERAQGLLAQGSTGVVRVGRAGEERRDGVAVFVESFAPPPRMLVFGAIDFASAV
                     ARIGKFLGYHVTVCDARPVFATRRRFPDADELVVEWPHRYLESTEVDENTVICVLTHDP
                     KFDVPLLRRALRTPARYIGAMGSRRTHEDRLRRLREEGMSEAELSRLAAPIGLDLGART
                     PEETAVAIMAEVIALRWGGTGRRLVEMTPLPIHR"
ORIGIN
        1 tgacccggtc gcagatcgcc tccgcctcgc ccatgtcgtg cgtggtcacc agcaccgtgc
       61 ggccctcggc gcgcagcccg gtcaccaggt cgcggaaacc gtgcgcggag accgggtcca
      121 tgcccgcggt cggctcgtcc aggagcacca cctgcggatc gtgcaccagg ccccgggcca
      181 ggtgcaggcg ctgcttcatc ccgcgcgaga aacgctccac ccggtcgtcg gcatgcgcgc
      241 ccagccccag ctgctccagc agttcggcgc tgcgggtcgc cagccggcgg cccgacatgc
      301 cgtacaacga ggcccagtag accaggttct gccgggcggt cagccggtcg tagagtccgc
      361 gctcaccgcc gaagacgatg ccgatgagcg ggcgcaccgc ccccgggtcg gcggccacgt
      421 cgtgcccgag cacgtgcacg gagcccgagc tgggcagcag caccgtggaa aggatcttgc
      481 acagggtggt cttgccggca ccgttcggtc cgagcagtcc gtgcacctcg ccctcggcga
      541 tgtccaggtc gatcccctgg agggcgaccc gctcgccggt gtcggcacca cgccgccggc
      601 ctccggtgcg gaaggtgcgg cgcagcgcgc gcaccgacac ggccgcaccg ggggaaggag
      661 cgaccgcgcc gcccccggcc gggtcggtgc ccggggtggt ggcccgcgtc atcgcccgcc
      721 ctccgtcggc tcgggccgca cgaagtgcaa cagcagggtg agccggtccg gagcaccggg
      781 cgccaccggg gtgacgcagt gccaggaatt cgccgagggc cgcatcagca ccgaggtgcc
      841 gagcagcggt cgtacctcgg ccgccacgtc ctccgggtcg gctgagcgca gcacccgcag
      901 cgcgcccgcc cattcgggcg gccagaccgg gttgaagtac cagatctggg tgaccgcctt
      961 gtccgcccgg tccgtgtgcg ggtcgatcca gccctgctgt gcgtaccgga cggcgcgcag
     1021 gtgcgcggta cagccgttca ggtcggtgcc catcgtccgc gcgagccacg cccggtagtc
     1081 gtcgccgagc agcgtcgcca ccaggctgcg ccactgcggc gccagcccgc gcacctcggg
     1141 ggcgggctcg ccgcggtcgg ccagggtgag gttgtaggtg ctgtagccct tgccggtggc
     1201 ggcgtccccg gcgcgcaggg tgtatccgcc ggccgggaag tgcgcggcca ggtccgcggc
     1261 ggcgccctgg tccccgaagc actcgtgcag caccgcccac ggataggggt cctgctggac
     1321 cgtgcggtgg cccggcgtct ggaggtcgat cacgcccgcg ttcacgccca cagctccacc
     1381 tggatggtcc agcgcagccg gccgtcgtcg gcccggaccg gctccacggc gtgccaggag
     1441 tgctcggacc gggcgaagac caccgagcgc ggcgcctcgg ggggcagcgt ggcgtgcggg
     1501 gtgccgccgc tgccggaggt gtgcacctcg aaggcgccgc cgtcgtccgg gccccaggct
     1561 tcgttgagat agatgacgtg gctggcgagc ttgccggact tgtcggtgtg gcagctgaca
     1621 tggtcgtcgg tcccgaagac gaacagcccg atctcggcgt gcctcgcggt gacgggcacc
     1681 tcgacggcgc gctggaccca gtccaggtag gcgggggtgc gcagggcgtc gacgaggtcg
     1741 cgccagaccg ggtccagccg gtccagcacc gcgcagtccg cgcccccccg caccagcggc
     1801 agcacctgca tggcgtaggc cttgtcgccg cccgcggcac gctccttgcg gtcgaacagg
     1861 tccgtcgcgg gcagcgcgcc gcgcagtcgc tccagcaggg ggaggggcag caggccgtcg
     1921 gcctgggccc agatgtaggg cgtccggtgc gccgtgacgg gagcgtcgag gtcgagcatg
     1981 gtctcctccg tgcgatgggg ttcgggggtc acagccgggc tgcctcgggc agcggccggc
     2041 cggagcggtg cgggcggtcg ggcggcggcg gtgcttcggg agcctgtggg ccgagcagca
     2101 ggcggggcac ggcgtgcccg gtgaccgggt cggcggggcc acgcagcaga tgcgcttcga
     2161 ggaaccgccg ggcggggtgt tcgggccggt tgacgagctg ccagatgtga gcggcgacca
     2221 cggcggggtc catgaaggcg tccagctcct ccggtgtcag accgaggaca tcgtggaagc
     2281 cgggcgtcgc catggcgccg ggctggatca gggtgacgcg gttgcgcggg tcggcgcgca
     2341 gcagttcggg cgtgagcgcc cgggtgaacg cggcctgggc cgccttgagc ccgcagtaca
     2401 ggctctgttc ctcgcgagcg cgccaggagg acgccgaggc gacggtgacc aggtgcagcg
     2461 gctgcggcgg cgagggctgc cgcagccggt cggcgagaag gcggcgcagc agccgcacgg
     2521 gcccctgcca cagcagcgcg gtgaggcggt cggcgtcctc ggccgcggtc tcggcgagcg
     2581 gctgtttcag gaactccccg gcgacccaga acaggtacag cgggccgggc ccgcgcagtt
     2641 cggccagatc gacggcgtcg acggccgcag ggtcggtgag gtccagcgcc cgggcgcgga
     2701 gcggctgtgc ccgggccgcg ggcacagccg ctgcggtcac ctccgccgcg agcgtctccg
     2761 cctcgggcac ctccgccgca ggcgcctcgg ccggggccgc ggaacggccg tagacgacga
     2821 cgccgcagtc gtgccgcatt gcctcgcgag ccagttcacg gccgagcccc cgagtgccgc
     2881 cgagcaccgc ggcgatccca cgcggcccct ttgcaccgct catcggcggg cccgctggag
     2941 cgcctcggtc acctcggccc agaaccgggg cacgtcgtcg agcatgtccc gcccgtaccg
     3001 cgcccggacc acgggcatgg cgtccagcgc cgccccgaca cctaccgcgc cgttgccggc
     3061 cgttgccggc cgcggcacca gccccaggaa gtcggtgaca tgcttgagct gccggatgtt
     3121 cgcgtcgaag tcgctgcgcc agcgcaggtc gccgggctcc tcgacggtga tctcccagcc
     3181 cttccggtca cgttcggcga ccgggacgac cacgccgcgc gggcgcaccg ccgccgcgcc
     3241 gccgatccgg gcgacctcca ggaactcgtc gatgtcgcag tagacccgca cccggtcggc
     3301 ccgggaccag gggcggtcgg cgtccacgtc gagcgggccg atcggctggt cgtagcggcg
     3361 cagccgggcc tcttcgaacc gccgccgggc cgggtgcccg ctgagcgtgg ccacgctgag
     3421 gccgatgcgg ttggaccagc cgctcatccg gggcgccccg tcggcaccgg cccaggcgaa
     3481 gaccaggtcg tcggagacga agtcccagcc cgcgcgggtg gcgacgagga acatcagcga
     3541 ggacttgccg ctgccgctgg gtccgacgac cacgatgccc tccccgtccc tggccacggc
     3601 cgagccgtgg aagacgggca gtccggcggc cgtcagctgg gcgccgacca ggaacttcac
     3661 cgttcgggcc acggcgcgca gcgcgcccgg tgagccgtcg ggcaacgcga ggtcgacctc
     3721 gcccgtgccg gggtgtgcgg tgagcagcag ctcggtggcg tcctcctcgg cgagttgcag
     3781 caccgtcacc acctcgggcg tgcgggccag gacgacctgg cgggtgccgt cgagcagcag
     3841 ggtcggcatg cgctccaggc cgtggacggt ggccgcggtg ggctcctcgg agccccgcag
     3901 gcgcacggtc agccggagca caccggcggg ggcaccggcg ccggaatcgg tcgtggcgaa
     3961 ggcgggtccg agaacgcgcg ggagcaactc ccgcacaccc gggacacggg agtcgacgtg
     4021 cagggcggcg aaggcgtagc cgagtgtgaa ggactcggag cgcggcgcgg cgcacggcgc
     4081 gggcggggcc ccgggagcgg tcgggcccgg gacggtggcc gagggcgaat cggtggctga
     4141 cggcaaggca ggctccagta cgggtcgcgt gggtcgggcg cggggaagcc gcgcggggtc
     4201 ggggcgcgcg gtcagggcgc ggggaccggg cacggtgtga gcccggcccc gagcgcggtg
     4261 agtttgccga gcatgtccgc gtagccgcgg tggacatggt ccaggccgtg cacctcggtg
     4321 cggccggggg cggcgagcgc cgtgatgagc gcgaccgcgc cggagcgggt gtcgcccggt
     4381 gtcagcggcg cgtccgccgg gcgcagcggg gcgccgccga cgacggtgag gctcgcgccg
     4441 gtggtgctgg tcggcacccc gacgcggccg aggtgctcgg cgtaggcata acggccgagc
     4501 cagaccaggt cgctgacgct ggagcggccg ggggcccgca tcatgacggt ggtgtagagc
     4561 gggagcgcgt cggtggacag ggtggcgttg cgggccacca ggtcggccgg gcgcagggtg
     4621 cccgggtcgc cggtgacggt gaggcggtcg ccgtcccact cgtgctggac gccgagctgg
     4681 gccagcgcgg ccagttcgtg gtgcatcatc cgccgcatcc ggtccggggc tccggtacgg
     4741 atctcgacgg tgcccccggt cgccacggcg caggcggccc aggtcaccgt ttccaggcag
     4801 tcgggggcga gctgcgcggc ggcccggccg tgcccggggc cgcggccgcg gatggtgacg
     4861 gcgccgccgt ccgggtccac cgcgacgccg acgcccgccg cgccgaggaa ggacatcagg
     4921 tcctgggtgg accagagcac cagcggatgg cgcagtcggc tggtcccgtc ggtcgccgcg
     4981 gccagcagca gggccgcctt ggtcacgctc gacatccggg agccggcgat ggttctcggg
     5041 tcgtcggacc agtccagcaa ctcgacgtcg gcgcagcggc ggcggtcgcg gcggccgtgc
     5101 acggagccgt cggcggacac ctcgaaacgg cagccgaatc gctccagcat ctccagcagg
     5161 tgcaggaagg gccgcccctg gcccatctcg aagtcaccca gctggtcgcc gccggcgccg
     5221 gggaactcca cctcaccgaa ccgggcgagc atggcgggca gcagatagag ggagccgtgg
     5281 atcttccggg tcagccgggc gctgagcggg gcggggcggg cggcggtggc gtcgagcacc
     5341 acctggtcgc cctcgaccga ccaggtgcag ccgagcagtt ccagttgctc cagcagcacg
     5401 tcgcgttcgg tcacctgggg aacgccggtg agcgtggccc gtacccccag ggccagcgtg
     5461 gccgcgaacg ccgcgaccat cgagtgtttg tgcccggcca cccggacctg gccgccgatg
     5521 cggccgccgc cgtggacgac gacagcgggg agatccgccg cggcggatcg ggaagaggcc
     5581 gggacggcct gcgcgatgag caccattcgg gacgccatct ccttcggctc tcccgaccgc
     5641 cggacaatcg gctgacgggg ggaagtcctc tgagctgcaa aacccaccag tattgggtgg
     5701 tcaagtctag tcactttgga gtcaagcata gtcattgcag tcagtcaata aactgtggga
     5761 tgctgccggg accgagtaaa ccgagaatca ccgaaccgga atcgaggcca ccgcgatggc
     5821 agatgccccc gccctccaga atctgggcat caacttccgc cccgtgcagt gcccgcacct
     5881 gcggccgggc cacttgcacc ggtccgccga cctgcgcacc ctcagccccg aggaatgcgg
     5941 caggctgtac ggcgaatacg gcatccgcgc cgtactcgac ctgcgcagcg cgcccgagcg
     6001 cgagcgcgac ggactgccgg ccacggccgc ctccgggctg ggcctcgtgg accaccatgt
     6061 gccgctcacc ggctacccgc acgacccgat cggctccccg cgtcccggcg cggccgacta
     6121 cgcccgctac tacaccggga tggtccgccg gagcagctcc gaggacctgc gcgccctctt
     6181 cgccacggtg gcccgagtcg cgcacgagcc cttcctgctg gcctgctact gcggcaagga
     6241 ccgcaccggc gtggtcaccg ccgcgctgat ggtcctcgcg ggctgcgacg acgcctgcgt
     6301 ggccaccgag tacgggcgca cggccgaggg cctgatcccc catgtggatc acttctcccg
     6361 gctgtggacc ggctacggcc acacccgcga ggacttcctg gcccgcctgg ggcagacccg
     6421 ccaggagacg atgctgctgt tcctggccac catgcgccgc gaacacggcg gcctggtccc
     6481 ggcgctgctg gaccgcggcg tctccccagc ggacctggac cgcatcggcg cgctgctcac
     6541 cgcgggggcg gccgcgtgag caccgcagcc ccgggtgcca ccgctgctcc gggtgccacc
     6601 gctgctccgc gggtcgcggc cgtcatcggt gaggccgccg gactcggccg ggctctcacg
     6661 gagctggcac tgcgccaggg cgtccccgtc ttccgcttcg gcagcgccga ggactgcgcg
     6721 ggcagccccc cgggcgccga gtcgcgcctg gtcgacctcg ccgacgccgc acagccctgg
     6781 accgtcgacc ctgccctgcc cggccccgct ctggtgttct gggtcgccgg gcgcttcctc
     6841 cagcagccct tcgccgaact caccgccgcc gacgccgaag ccctgacccg gcacagcctc
     6901 accgggccgg ccgccctgct ggcccggatt ctcgccgcgg acccgcaccc ggtgcacctg
     6961 gtcaccgtcg gctctgtctc cgcctggcgc gcccggcagc accaggcgta ctactgcgcc
     7021 ctgcgcgccg cgcagtccgc gctcacccgg aatctgctcc cggagctacg ggagcactca
     7081 ccggacggcc gggcgacgct ggtcgagctg ggcggcctgg ccgtcccgcc gctgccgccg
     7141 tacccggcca tggactacgg caccacactc gacccggtcc acgtcgccga gctggtctgg
     7201 cggctggcgg acacccagac cgaaccgctg acccatgccg tgatccagcg cgacaagcgc
     7261 cccggtgccg agggcagccc tttgttgtcc ttccacggcc cggtgcccga tccgccgccg
     7321 cacccgaggc cggatacgct ccggcccgtg ggcacacacc cgaaccgcga ggaacgcggg
     7381 gaagtggagc agcagcgcac gtgagccgcc accccatggt catcaccgcc tacgaccccg
     7441 tctggcccga ggcgttcgcc gtcgaggcgg cgcggatcgc cgccgtgtgc cctgtcggca
     7501 cggccgtgga gcacatcggc tccacggccg tccccggtct ggccgccaaa cccgtgctcg
     7561 acgtgctcgt gggcgtggcc gcgctggagc cggagggtgc cgcgtgcgtg cgcgcgctgg
     7621 tcgcgaacgg ctaccgctac aagccggact tcgaggcggc catgccggat cgccggtacc
     7681 tcacgcgcag caccgccgac ggggtccgga tcgccaatgt ccacctggtg cgccgcggcg
     7741 atccgatgtg gcgccagacc ctcgccttcc gcgacgccct gcgccaggac ccggcgctgc
     7801 gcgcgggcta tgaggccgcc aagcgcgccg ctctcgcggc cgcgcccgag gacgtgcacc
     7861 gctacaacga cgcgaaggcg ccgttcatcg cgcgggcgct ggaagcactg ggcgtcgccc
     7921 cgccccgacc ggaacaacgc tgagcctcgg tcgctccggg ccggccgcgg gccggccggc
     7981 ccgcggccgc taacggttgt cgtccggggc ggccacggcg tccctccggt cccgccgagc
     8041 cggcctgccc tgcccaccgc tgtccaccga cgccgtcaac gcctccagca gtcccggcac
     8101 ctggctccgc ctggtcaggc ggaccaccgg gcagtccgcg ccctgacggg ccagcagttc
     8161 cgccagcgcc gggcgcctgc ggcggcggaa ggtgaggatg aagcggagga aggacgtcgc
     8221 gtccggcggg agccgcaccg cgccgtccgc ggccgaggcg tagccggggg cacgtccggt
     8281 cagccgccag cgggcggtgc ggcgcaggta gccgaggacg cagacccggg tggggtagtc
     8341 cagccacacc accgcgtcgg cccggtgcag ccggtcggga agggtcgtgc tgtgcaggcc
     8401 gtccatcacc caggacgtgc cctgcacaag aacctcgtgg tcggcccgcc accgctccgc
     8461 aggaccgcgg acctgccagg cccggtcgaa gtagtggtcg tccaggccga cgtagggcag
     8521 accggtgagc gcggcgaggc gcgtcgccag ccaggtcttg ccgctgcccg gacagccgac
     8581 cacggccacc cgccgggcct gtgccagcgc cccgagcacc acccgctcgg gggccggtcc
     8641 gccgcctgct cggtccgccg tcactcccgc cccgcccccg ccccgtcgcg cgtggcctgg
     8701 tcatcggccg cctgggacaa cgcggtgagc gcccgccgca gcaccggtcg ctgcgccatg
     8761 ccgacccgca gcaccggtcc catgacgccc agcgggcgca gatcccggac ggtgatcccc
     8821 tcctcggcca aggcgtccag cccgcgccgc accaactggt cggtgccggc gcgcaccgcg
     8881 acgaagttcc cctgcgaggg cagcgcggtg aagcccggca gggcgtcggc cgccgtggcg
     8941 aaccaggcgc ggtcggcggc gacctcgcgg tggacggcgg cgacctcgtc gccgtggcgc
     9001 agcagatgcg cggccaggtg cagcgcggtg acggagaccg gccccggggt gttccagcgg
     9061 gccaggtagg agatcaggtc ggggtggccg tgcaggtagc ccaggcgggc cccggccagt
     9121 ccgtagccct tggagaagga gcggagccgg agcaggtgcc ggtggtgccc ggtccgcgcg
     9181 gggccggccc agcgcggacc gtcctggaag tcgcggtaca cctcgtcgac gaccagcagg
     9241 ttgccggcgg cggcgaccgt cgcgcagagg ttttccagtt cctccggcgt gtgcaccgcg
     9301 ccggtggggc cgttggggtt ggacagccac accacggccc gcccgggacg ggcggcctgg
     9361 agccggatca gctccgcggt gtcgaaggcg tgccgctgcg gcaggtaggg ggcggtcagc
     9421 agctctagtc cgcgcagccg cgcgtagtcc ggcagcgact ggtagttgag ctgctgggtg
     9481 accgcggcgg caccgagcgt ggggcccagc gcctcggtga gcagccggta ggcgtcgtcc
     9541 gacccggcca ccagcagcag cgattcgggg ctggtgcgca ggcggtcggc cagcagccgg
     9601 gtgaccgcgg tcccggaggg gtagccggcc aggtccgcgg ccggcaggtc ggacagggcc
     9661 tctcccgcca gccgctccag gacggggtgg cgcagttcgt tgctggccag attgacggca
     9721 ccggggaccc ggcggcggcg gtaggtccgc agggcctgca ccggcgaggc ggcgaccgcc
     9781 tccagcatcg tcgggcgcgt cctcacggcg cttgcagcct tcatggcggc cttcttcctg
     9841 atcaccggcg cgcggcggga ccgagcgcac gaaagcacag taaacatgct gtcaatgcaa
     9901 gtcaatattg ctagtcatgc tctgtcagga ttacttgact cacgcaaatc aatggtgtca
     9961 tatacctctg tcgcgatccg tcgatctgtg aggcgagctg atgtcgaaaa tcctggtggt
    10021 ctggccgcca cacgtccccg gctacttcaa tgccggacac cacacgccgc tcttcgaagt
    10081 cgccgagtac ctgcgtcgcc gccccggtgt cgagcgggtc gacgcgctcg acggcggagc
    10141 gctgaacgtg aactggaagg acctcggcgc caccctgtac cagggccgtt acgacgtcat
    10201 cgcgatgatg aacgactacg acgccgtcga cgggttcgag cgcttcctct cctacgcccg
    10261 cgagctgtcc cccggtgcca aggtgatcac cttcggccgc ctgtccgcgc agaaccccgg
    10321 gcactttctg cgctacgacc ttgacgccgt ggtgcgctcg ggggacgtcg agtgcggggt
    10381 gggcgactac gtcgacgccg tactcgccgg ggagcccgag cggccgttgc caggcgtcca
    10441 ggtacgcacc gccgacggct ggaccgcgcc caccgccccg ggccgcaccc tggaaccgga
    10501 cgagtgggcg ctgcccgacg tccgcgagat cccctacgag gcctacgagc gcctgtacgc
    10561 ccgcgacgac cgcaagttct gcggcatccc gttccgccgt gaactggtcg tgccgatcgc
    10621 ccgggggtgc cccgtcggct gttcctactg cgatgtgcac gagatcttcg gcctgcgcga
    10681 gcgccgcctg ggcgtcgacg ccgtgctgga gtacatcgcc gccgcccgcg aggcggaacc
    10741 ctcgttcgag tacgtgtcct tctacgcccc gaccttcacc ctgaaccgcc cctggaccag
    10801 ggaactgtgc cgccgcctgc tggagcagcc cgaccgtctg ccgtggaagt gcaccaccac
    10861 ggtgccgcac ctggacgaga aaatggtgca actgatgggc gccgccggct gcgtgcgcat
    10921 ctcggtcggc ctggagaccc tggacgagga cggccacggc tcgctgccgc gctccaagcg
    10981 ggtgcaccag gaccggttcg agagcctggc ccgctggtgc gccgacgcgg ggatcgaact
    11041 caacgcgttc gtgatggtcg gcctgcccgg cacgtccccc gaaggcaccg ccgccaccgt
    11101 cgccttcgca cgctcgctcg acgtccgggt gcgccccacc ctctacacac ccctgcacga
    11161 cctgcggccc accatgacca ccgccgaggt cagccgctac aaccggcaca ccctgaccac
    11221 accgacgccg cccgagctgg cggagcagca ctactcccac atcttcggtc ccgagtcccg
    11281 gctgacgagg gttcaggagc gcatcccgcg ggccgccgcg ccggtccccg cgcccgcgtc
    11341 cacgtgatcc gcgcgagcgc cgcgccgccc gaggtcgtcc cgctgacgcg cgccgtctgg
    11401 gaacaggctc tgcggcagga cccgcaggcg atggcgacac agaccccggg ctggctggac
    11461 gcgatctgtg ccgagggccc ctgggcggag gcgggccgcc tctaccggtg ggacgacggc
    11521 acccggatcg tgctcccgct ggtcacgcac accggaccgc ccggacccgg cagccccgaa
    11581 ctggcctcct ggcccaccga atggggagtg ggcggcccgc tctgcccgga cgggccgccc
    11641 acttcggcgc ataccgcggc cgtcctggcg gacctggccg acgtgcccgg ccgggtccgg
    11701 ctgcgcatcg gcccgctcac cgcgggaccc tgggccgagg ccgttcccga gcgggccggg
    11761 cgcaccccgc gcaccaccca tgtggtcgat ctcgcgggcc cggccggcgc ctggcggcag
    11821 cggctccacc ccggcgcccg acgctccatg cgcaaggcgg cccgctccgg cctggacgtc
    11881 acccgcggca gcaccgcgca cgacttggag gtcttctacg ccctctacca gcagtccatg
    11941 gaccgctggg ccacacggtc cggcgagccg gcggaccagg tgcggcgccg gatcgaggcc
    12001 cgcgacccgc tgcgcaagct gcgcacggtc cgcgaccgtc tcggcggcgc ctgctccgtg
    12061 tggacggcct ggtaccgcgg cgaacccgcc gcctcggtga tcctgctgcg ccagggccgt
    12121 caggcgaagt actggcgggg tgccatgtcc cagccgctgg ccgcgcccac ccgcgccaac
    12181 cacctgctgc atgaactggc gctccaggag gccgccgacg cgggctgcac ccactaccac
    12241 atgggcgact cccacccggg gggcgtcacc cgcttcaagg agtcgctcgg cgcacggccc
    12301 taccccaccc cggcttacct gctgcccgcc gcgcccctca ccgcccgctg accgcgacgc
    12361 accgttcgga gcccgacatg cccgtcatgg acgcctcacc acaccccgat ccgccgcact
    12421 cggccgaacg catcgtgcag gccacccgcg actactacgg cctggaccag gaccgccccg
    12481 accgcctgct gcaccgggcc gagcgctcgg accccaagtt ccgcctcacc ctgctcagcg
    12541 cctaccacca cgcgcacccc ggggcgctgt ccgcctcccg cgtccatgaa ctcgacgagg
    12601 cccgcgcccg gttggcggcg tacgccgccg tccgggaccg gctcgcccag gtggtccccg
    12661 ggctgagccc ggtcaaaggc ctggccatct ccgcctgcta ccccgccccg ttgctgcgcc
    12721 accagggcga cctcgatctg cacgttcccg atgaagcggg gctgtggcgc gccgcgcagg
    12781 cgctgatctc ggacggctgg cagcacaccg acctcgcggt gcgccaggtc gaccacgccc
    12841 ctgcccacct gctgacgttc taccgcccgc acggtgacga cctggctcgc ccgctctacg
    12901 tcgaactgac cgacgtcgcc tggctcggtg acggccgccg cagcatgccc cggcgcactc
    12961 ttcccgccac tgccgctgcg gacggcgcag cgcgcgaggg cctgccggcg gacgacgtcg
    13021 tgaccagtct gctcttcctc tgtctcgaag gactcgaacg cgccctgggt ctgcgggacg
    13081 ccgtcgacac ctggcttctc gccgtccggc tgacagcaga ggaccgcgcc ctgctcaccg
    13141 acctgatcga ccggctgggg ctgcacgacg gctaccggcg catggtcgct gcggcggggc
    13201 gcgccggact gctggccgac ggcgggctcc tgcccggggc accccgcccg cgccgccgaa
    13261 ggcccacgct gcggcgcccg gacatcgccg tcctgaactg gctccagtgg gccggcttct
    13321 accgcggccc gtcccgactg cgcagcgccg tctgggagcg gctcagcatg cgcatcgacg
    13381 cacccaccgc gttccgcggt ggcatgtggg ccttcggcat ccccgccgag gcgctcgggg
    13441 accacgcccg cactcccgcc ctcggcgaca cgcccccggc tctccaggag accgccgtcc
    13501 tgcggggccg ccgcaggctg tccacccctc tcggcgactt cctgctcgtc tcgggcccgc
    13561 gcgtccccgc cggcatcctg gacgccgcct gagcggatcg accggtgtcc gcgtgacctg
    13621 gctgacgggt gcgcaggggg cacatggccc gccgcccccc cgaggtcgtt cacggaaccg
    13681 agtacgcctg ccgtgacgcc gggcgactcg gcggagctcc cggccgaatc tccgttcgcg
    13741 gcgagtgccg tacggcagtc cgacgtcgcg ttcgcccgtc ctcctcgccg gcggcaccgg
    13801 ggcagcgcgg caccggaccc ttccggcgca aagccccccc caagacccgt agggaccgga
    13861 ggccgctcgg ctccggtccc tacgggtggt tcgggtgggc tcaggcggcc gtgatctgcg
    13921 ccgcggtgcc gtgcaggcgc gtgacgacct cggtcagctg ggcggcgacc tcggcgtcgt
    13981 cggccgggtg ggtctcggcg aagcgggtca tggagccggg gatggagagc ttgatgtcct
    14041 cgatgacctt gccgccggcg atgccgaccg acttgcgggt gtcgtcctgc gcccacacgc
    14101 cgccgaactg gccgaacgcg gtgccgatca cggcgacggg cttgccgccg aaggcgccgg
    14161 cgccgtacgg gcgggacagc cagtcgatgg cgttcttcag gacggccggc atggtgccgt
    14221 tgtactcggg cgagaacagc aggaacgcgt cggcgccctg ggcggccgca cgcagggccg
    14281 cggcggcggc cgggacgctg ccctcgacgt cgatgtcctc gttgtagaag ggcacatcgg
    14341 cgaggccctc gaagatcacg acctcggcgc cctcgggggc gagcttggcg gccgcctcgg
    14401 ccagctgacg gttgtgcgaa ccggcacgca ggctgccgac gagcgcgagg atacgaacag
    14461 acatgtgaaa tctccagggg ctgaaacatc gccgttacga tccggaccaa ggtccgttta
    14521 aatttctacc accacaaccg gaccggggtc cagttctgtt cccgatgctt tactctgtcg
    14581 tcatgtccag cgcgccgcag cccttcccga cgccgcagga gccctccgac gcgccacccc
    14641 tgctggagct cggcacggct cccgaggagc cctgcctgcg cgccgacgcg gcccgcaacc
    14701 gcgcccggct gctggaggcc gccgcccgcc tgatcgcgga gcacggcgtg gccggcgtca
    14761 ccatggaggc cgtcgccgcg gcggcccagg tcggcaaggg cacggtcttc cggcgcttcg
    14821 gcgaccgcac cggactcctg atggccctgc tcgaccactc gggccgccgg ctccaggccg
    14881 acttcctcgg cggccccccg ccgctcggcc ccggcgcgcc gcccctggag cggctgcggg
    14941 cgttcggcat cgcggtgctc taccgctcgg ccgagcagct ggagctgcaa ctcgccgccc
    15001 agcccgaggc gtgccgccgc ttctcccacc ccgcgacgca ggcgctgcgc acccatgtga
    15061 ccatgctgct gcgccagatc gtgcccgacg cggactgcga actgctctcc cagaccctgc
    15121 tggcctccct cgacccggcg ctcatccacc atctgacccg gcagcgcgga atgcccatgg
    15181 cccgtttgga ggcggcctgg gtggacctgg tcgcacgggt gacgcgcacg cagcagcccg
    15241 tctgacaaga ggccgaacag ccggtgcgcg cgcgggagtt ggtcaaaaag cgaaccacat
    15301 tcccccgccc gccacacccc cggaccgctc tgccaagatg cggtctgtca tggtgcagat
    15361 accgaacact cccacgagtg ccgatgtggc ccgcctggcc ggcgtctcgc gcgcgaccgt
    15421 gtcctacgtg ctcaacaaca ccgatgccgt gcggatcagc gaacccacgc ggcggcgcgt
    15481 ccacgaggcc gcgcgggaac tggggtacgt cccccacgcg gccgcccgca gcctgcgcgc
    15541 cggacacagc cgtaccgtcc tcatgcccgc cccggcgatc cccgtcggac ccctctacag
    15601 cgcgttcctc aacgaggtcc acagcgccct gggccggctc gactacaccg tcgtccagta
    15661 cggctccgtc ggcctcccgg gcgacgaagc cgcccgcgcc tgggccgagt tacggcccgt
    15721 ggccgtcctg gtgcccggta ccgggatcgg cccgcggggc gtcgccgtcc tcaaacgctc
    15781 cggcgcccgc gcggtcgtca ccctcggtcc cgaacgcgtc gagggcgccc acgccctgct
    15841 gatggaccat gacgccgtgg gccggtgcgc ggccgcccac ctgtacgaac gcggcaggcg
    15901 gcggatcggg gtcgtcgtac ccgaggagcc cggcctggag gtctattcga ggccccggct
    15961 cgacggcgcg cggcaggcgc tgcgcggcac cggggcgagc gtcatcggcg tgccgctcgc
    16021 ctacaccgag cgggccgccg ccgaactcgc ggcgaactgg cccgggttgg acgcggtgtt
    16081 cgcctacaac gacgagtacg ccatgctgtt gatgcgcggc ctccaggacg ccgggcggcg
    16141 catccccgag gacgtggccg tgatcggcgc cgacgacctg atgctcggcc ggctgctgcg
    16201 gccccggctg agcaccgtcc gcatcgaact gcccgcgggc cgcgacctcg ccgccctggt
    16261 cgaccgcgcg gtgcgcgacc cgggcggcga acccgaggtg caccgggtcc tcggctcctc
    16321 ggtcgtacga cgcgagtcca cctgaatccc ggtcccggcc cggcccccgg cggctaccgg
    16381 gcctggccct cctcggcgcc ctcctgggcg gcgatgctct tgcggacctc gtccatgtcc
    16441 agcccgcggg cctggccgat gacgtccgtc agggccgcct cgggcagcgc gcccggctgg
    16501 gcgaacacgg ccacccggtc ccgcacgatc atcagcgtcg ggatcgactg gataccgaag
    16561 gcctgcgcca gctccggctg ggcctcggtg tccaccttgc cgaacaccag gtccggattg
    16621 tccttcgcgg ccttctcgta caccggcgcg aactgccggc acggaccgca ccaggacgcc
    16681 cagaaatcga tgagcacgaa gtcgttgtcc gtgaccgtct ggtcgaagtt gtccttggtc
    16741 agttccacgg tgccgctcat ggcctgggtc cctcttcctg gtccgggggt gtgccgacgg
    16801 cggaaacacg gccggtgggc cgcctattcc gggcagttcc cgcgtcggcg cgggcactgc
    16861 ccgggcgcac ccggatgcct ctcgcgcacc cgggtgcccg tgtgcgcgct cgtacccatg
    16921 tggccgccgc gcacaccacc caccagactg accccatgac ggaaacgacg gaatcggaaa
    16981 ccatcgcgta cgacgtcgtg gtgctcgggg ccgggcccgt gggggagaac gtcgccgacc
    17041 gcacccgcgc ggccggcctc accaccgcga tcgtggagag cgaactggtc ggcggcgagt
    17101 gctcctactg ggcgtgcatg cccagcaagg cgctgctcag gccggtcatc gcccaggccg
    17161 acggccgccg gctgcccggc ctcgccgcgg cggtccaggg ccccctcgac accccggccg
    17221 tgctggagcg acgcgacaac ttcacctccc attggcagga cgacgggcag gtcgactggg
    17281 tggagggcat cggcgccgac ctctaccggg gccacggccg cctcgcggga ccgcgcacgg
    17341 tcaccgtcac cgtgtccgac ggcggcgtca ccaccctcac cgcccggcac gccgtcgtgg
    17401 tctgcaccgg cacccgcgcc cagctgcccg acctgcccgg actcgccgag gtgcggccgt
    17461 ggaccagccg ggaggccacc agcgcggaca cggcccccgg ccggctgctc gtcgtcggcg
    17521 gcggtgtcgt cgccaccgag atggccaccg cctgggcggc gctcggctcc cgggtgaccc
    17581 tgctggtgcg cggcaagggc ctgctcggcc gcatggagcc gttcgccggg gaactggtcg
    17641 ccgaggcgct caccgaggcc ggggtggacg tgcgcacggg cgcgtccgtc acctccgtca
    17701 cccgggagaa cggcaccgtc gtggccctca cccgtacggg tgagaggttc gaggccgacg
    17761 agatcctctt cgccaccggc cgcgtcccgc agaccgacga catcggcctc gacacggtcg
    17821 gcctggagcc cggttcctgg ctggagaccg acgacaccct gcgggtcgcc gggaccgact
    17881 ggctgtacgc cgccggtgac gtcaaccacc gcgcgctcct cacccatcag ggcaagtacc
    17941 aggcccgtat cgccggtgcc gccatcggtg cccgcgcggc cggtaccccg ctgctggacg
    18001 gcccctgggg cccgcacgcg gccaccgccg accacgaggc cgtaccgcag gtcgtgttca
    18061 ccgaccccga ggccgccgcg gtcgggctct ccctcgccga ggcggaggag gccggccacc
    18121 gggtccgcgc ggtcgacgtg gagttctcct ccgtcgccgg tgcggccctg tacggcgacg
    18181 gctacaaggg ccgcgcccgc atggtcgtgg acctggagga cgagatcctg cggggcgtca
    18241 ccttcgtcgg ccccggcgtc ggcgaactca tccactcggc cacgatcgcc gtcgcggccc
    18301 acgtcccgat cagccgcctg tggcacgtgg tcccctcgta cccgaccctg agcgaggtct
    18361 ggctgcggct gctggaggcg taccgggaca actgagaggc gcgttacggc agttcgaagc
    18421 cgagggcggt cgccgccgtc gagggggtcg gctgggacca cagggcggcg acggcctcgt
    18481 tggtggacag ggagcgcggt tcggcgcggt cgaggtagag ggtgccgtcg aggtggtccg
    18541 tctcgtgctg cacgatgcgg gcgggccacc cggtgaacac ctcgtccacc gggcgcccgc
    18601 actcgtcctc ggcgcgcagc cgcacctcgg tgtgccgggc caccaccgcc tgccagccgg
    18661 gcacgctgag gcagccctcg aagaacgcgg cgcgcgtcgt gccgacgggc tcgtacaccg
    18721 ggttcaccag gacccggaag ggctgcggac gccggccccg gaccgcggcg atctcgtccg
    18781 gcaccggtgc cgggtcctcc aggaccgcga tccgcagctc cacaccgacc tggggcgcgg
    18841 cgaggcccac gccgggcgcg gcgtgcatgg tcagacgcag cgcctcgacg aaacgggcca
    18901 gcagggcggg gccgagctgg ccgtcgtacg cctcggtggg gcggcgcagc accggccggc
    18961 cggcggcgac gatgggcagg gggccgccgg cggcgaggag ttcctcgacc cgttcggcga
    19021 gcggtgcgtg atcacggtcg gatgccatcg cgccaggatg ccacgggggc ccagccgggg
    19081 acgaggcgcc caccccgggg tgggtacgag gcgcccaccc cggggtgggt acgaggggcg
    19141 cggacccggg atgggtacga ggcgcgcggc cccggggtgg gtacgagggg cgcggcccgg
    19201 ggcgggcgcg tggccgggcg ccggggcgtg ggacctcggc gcccggtgtc gcgccacggc
    19261 gcctcagcct cgcgcgggct cgcccgccag cgcggcggcg atccgcagat gccgctccgc
    19321 ctccgcgtgc cgcgactgcc gttcgagcgt gcggcccagc atcagccggg cgtagtgctc
    19381 caccggatcg cgctccacga tcgtccgcag ctggtcctcg gcccgccgca gctgcgccga
    19441 gtggtagtac gcgcgggcca gcagcagccg gggcccggtc tgctccggta cctcctccac
    19501 cagggcggcc agcacgcgcg ccgcccccgc gtagtccttg gccgcgaaga acgcctgggc
    19561 gcgctcccag cgctcggccg gggtgccgtg gccgtagtac gtggtctcca cctgtgacct
    19621 ccttcggcgg ccacaacggc accagtcagt tcaatattcc actacccgct cccgggggcc
    19681 ggtccacgtc cggccggcct ttctcggtga cgccggccac cggcacccgc gcgccccccg
    19741 ggtgaccggc gtcggcgacc cgcgtcagcg atggatcggc agcggggtca tctccaccag
    19801 tcgccgcccc gtgccgcccc accgcagggc gatgacctcg gccatgatgg ccaccgccgt
    19861 ctcctccggc gtacgggcgc ccaggtcgag cccgatcggc gcggccagcc gggacagctc
    19921 cgcctcgctc atgccctcct cgcgcagccg ccgcagccgg tcctcatggg tacggcggct
    19981 gcccatcgcg ccgatgtagc gggcgggtgt gcgcaacgcc cgccggagca gcggcacatc
    20041 gaacttcggg tcgtgggtga ggacgcagat caccgtgttc tcgtccacct cggtcgactc
    20101 cagataccgg tgcggccact ccaccaccag ctcgtccgcg tccgggaagc ggcggcgggt
    20161 ggcgaacacc gggcgggcgt cgcacacggt gacgtgatag ccgaggaact tgccgatccg
    20221 ggccaccgcg gacgcgaagt cgatggcgcc gaacaccagc atccgcggcg gcggcgcgaa
    20281 ggactccacg aacacggcga cgccgtcgcg ccgctcctcg cccgcgcgcc cgacccgcac
    20341 caccccggta ctgccctgcg ccagcagccc ctgcgcccgc tcgaccacgg aggcgtcgag
    20401 gcgggcgtca ccgagcgtgc cccgcccacc ggacggcgtg acgatcagct gaccggcggg
    20461 cgcggccgtg ggatccggct ccgcgccgcc gccctcgtcc ggcagcggcg acaccaccgc
    20521 caccggccgc cccgcgccca tcgcctccag cacccccggc agccccggga aacggcccgc
    20581 gcccgccggc cgtaccagga tctcgatgat cccgccgcag gtcaggccga ccgcgagcgc
    20641 gtcgtcgtcg ctgacgccgt aggtcacgag ggcgggctcg ccgctctcca ggacctcgct
    20701 cgccagctcg tacaccgcac cctccacaca gccgcccgag acgctcccga tcacctcgcc
    20761 gtcctcggcg accgccagcg aggagcccgc ctggcgcggc gccgacctcc aggtccgtac
    20821 gaccgtcgcc accgcgaatc gcttgcccga cgcactccag gcggagaggc cctccgcgat
    20881 gtcccgcatc cgtgtgcctc cttcggcggc gtccctcacc gccacaccca ccgcataccc
    20941 gttcgggcct ctgcgcaggc cgtacggcgg tccgcgcctc ggcgcccggc ccccgcccaa
    21001 accccgtggc ggccgttctc ccccgtccgg cgtccggatc atgcgaatgc cgtccgccgc
    21061 atgtcaacgg cagcttaagt cttcgcttaa gtgaccgcgc ccgtcgtgtc gagcgagtta
    21121 agcgaaggct taagcagcga ttgacactcc gcccggacgg aggcgcaatg atctttggac
    21181 aacggcgccc gacgcgcccg gctgcccgcc gggcgagaca ggggagtgcg gcatgcaggt
    21241 tcccgctccg ttcgaatacc agcgggtggg cacggtggac gaggcggtca cgcttctgga
    21301 ccggctcggc gacaccgccc ggctggtggc cggcggacac agcctcc
//
