LOCUS       NZ_CP047144            21986 bp    DNA     linear   CON 30-JAN-2024
DEFINITION  Streptomyces sp. HF10 chromosome, complete genome.
ACCESSION   NZ_CP047144
VERSION     NZ_CP047144.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. HF10
  ORGANISM  Streptomyces sp. HF10
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7814787)
  AUTHORS   Li,J., Ni,J. and Li,Y.
  TITLE     Multiple polyene macrolides produced by antifungal Streptomyces from
            gut of Macrotermes barneyi facilitates the termite-fungus mutualism
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7814787)
  AUTHORS   Li,J., Ni,J. and Li,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-DEC-2019) State Key Laboratory of Microbial
            Technology, Shandong Unversity, 72 Binhai Road, Qingdao, Shandong
            266237, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 10-NOV-2018
            Assembly Method                   :: SPAdes v. NOV-2018
            Assembly Name                     :: SDU_Sthf_5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/30/2024 05:29:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,091
            CDSs (total)                      :: 6,988
            Genes (coding)                    :: 6,640
            CDSs (with protein)               :: 6,640
            Genes (RNA)                       :: 103
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 79
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 356
            CDSs (without protein)            :: 348
            Pseudo Genes (ambiguous residues) :: 0 of 356
            Pseudo Genes (frameshifted)       :: 235 of 356
            Pseudo Genes (incomplete)         :: 154 of 356
            Pseudo Genes (internal stop)      :: 18 of 356
            Pseudo Genes (multiple problems)  :: 53 of 356
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:39:54
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6856656
            Orig. end                         :: 6878642
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP047144.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Jinfeng Ni.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21986
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="28"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21986
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21986
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11986](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11986)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(261..276)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.68"
                     /tool="antismash"
     gene            complement(785..1915)
                     /locus_tag="GR129_RS30445"
                     /old_locus_tag="GR129_30445"
     CDS             complement(785..1915)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) azdH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019060249.1"
                     /locus_tag="GR129_RS30445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_30445"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_159706703.1"
                     /sec_met_domain="azdH (E-value: 2.9e-127, bitscore: 423.1,
                     seeds: 3, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFLHTERAVLDRLLPGLDAALAAHPLAELERAPSPAIEAFREAG
                     GPGLLVPAEHSGAGATVLQAVRAQRAVGARCPSLAVATTMHHFSVAGLVETARHGTGME
                     GLLLTAVAGERLLLASGFAEGNTGQNILRPAIRAELRDGRVVLNGSKKPCSLSRSMDLL
                     TASVTLTGADGVARLAVAIVPAKTPGLSVRPFWNSPVLAGAESDEVVLTEVELDPQMVV
                     TTEVTADAVPDSLNVAGFLWFELLLTAGYLGVVSALVERVLAKPRGFGGDPTPFLVDVE
                     AAMLAVEAVAMAMETEAWDDTLLVRALHARYAAQDTIARTAPRCLSALGGMAFIGSPDG
                     TYLASAAAGLGFHPPSRARMAGPLREHLDGARLRIG"
     gene            complement(1956..3149)
                     /locus_tag="GR129_RS30450"
                     /old_locus_tag="GR129_30450"
     CDS             complement(1956..3149)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="GR129_RS30450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_30450"
                     /product="cytochrome P450"
                     /protein_id="WP_159706705.1"
                     /sec_met_domain="p450 (E-value: 4.4e-22, bitscore: 77.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFTAEGKEDPYPALAELRRIAPVYYHEKLDTYFLTRFADCQQVLS
                     DPSCLTPDLTWCETELPDWREHPAAVFFYSSLLRANGTDHVRLRRLVADRFSARRIAVL
                     TERIETTTAALLDRFADATRDGGAADFQELVGYPLPVAVVGDLIGVPHADQDRFHHYGQ
                     DASRLLEPVRTDEDWKRADEAVTALRGYFARLIALRRRRPADDLVSALLAVREMDDGRL
                     AESELLDMLLLVFVAGFETTTSLLGLTVHALLSHPDQLALLREDPALVPNGVEESLRWD
                     TPVRMTERIATRPLTVGGVAIPQGGNITTVLAAAGRDPARHPDPDTFDVLRPDIRVLSF
                     SAGAHYCLGAALARLEGAAVVRQLLARFPGLAHARPPVRRDSISLRAFTRLPLVTSG"
     misc_feature    complement(3372..3385)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.06"
                     /tool="antismash"
     misc_feature    3375..3388
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 17.96"
                     /tool="antismash"
     gene            <3501..>3767
                     /locus_tag="GR129_RS36235"
                     /pseudo=""
     CDS             3501..>3767
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972166.1"
                     /locus_tag="GR129_RS36235"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="sugar ABC transporter substrate-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRLTAAPVARQAPGDTFRGTRGGIKLVCSAEPDALENALGKAERA
                     DIPVVGPNSGQADRKRFGPLEFFGRDESVAGEAFGNKLNTTGAE"
     gene            3884..4786
                     /locus_tag="GR129_RS30460"
                     /old_locus_tag="GR129_30460"
     CDS             3884..4786
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019522605.1"
                     /locus_tag="GR129_RS30460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_30460"
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="WP_159706709.1"
                     /transl_table=11
                     /translation="MPHVLDRVRVGSAPDSWGVWFPDDPRQVPWERFLDEVAEAGYAWI
                     ELGPYGYLPTDPARLTEEVARRDLKVSAGTVFTGLHRGPAVWADTWAHVSQVAALTQAV
                     GARHLVVIPSFWRDDKTAEILEPSELTAEQWGHLARGMERLGRQVKETYGLDIVVHPHA
                     DTHIDTEAHVERFLDATDSGSVGLCLDTGHYAYCGGDSVRLIETYGERIGYLHLKQVDP
                     AVLAEVVARELPFGPAVARGVFREPPHGVPELGPVLEAAQKLGVDLFAIVEQDMYPCAP
                     DKPLPIAERTRRFLRSCGA"
     gene            5011..5205
                     /locus_tag="GR129_RS30465"
                     /old_locus_tag="GR129_30465"
     CDS             5011..5205
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676274.1"
                     /locus_tag="GR129_RS30465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_30465"
                     /product="hypothetical protein"
                     /protein_id="WP_145490652.1"
                     /transl_table=11
                     /translation="MTHRTEPRNTAQDTADAAARRRERFGTLPERIRPEDTVETSPATL
                     PDPARDRYHADEWLVRYCG"
     gene            complement(5229..6233)
                     /locus_tag="GR129_RS30470"
                     /old_locus_tag="GR129_30470"
     CDS             complement(5229..6233)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006380934.1"
                     /locus_tag="GR129_RS30470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_30470"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_159706711.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 9.5e-19, bitscore:
                     66.9, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 6.2e-25,
                     bitscore: 86.2, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIGILGLGRIGVFHAETLSGLDAVASLVFADPLADAAKAAAERF
                     GAQVADSPGALLAAGVDALVVAAATDAHPALIRAGVAAGVPVFCEKPVARTMAEGVALR
                     DRVRGSGVPVQIGYNRRFDAGFAAARAAVRSGELGALHTVRCTTLDPAPPPAAYVAASG
                     GIFRDCSVHDFDIIRWVTGREVTEVYAVGGNRGAVPIARAGDADTAGAVLTLDDGTIAL
                     VSNSRHNGRGYDVRMELHGFADAIAVGLDERLPLRSAEPGAGFPSGTPHAFFMDRFADA
                     YRAELTAFTEVVAGTRTSPCTVEDALEAGWIAEACTLSRAEHRPVTVAEVRQV"
     gene            complement(6302..7474)
                     /locus_tag="GR129_RS30475"
                     /old_locus_tag="GR129_30475"
     CDS             complement(6302..7474)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020116695.1"
                     /locus_tag="GR129_RS30475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_30475"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_268982814.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 1.1e-22, bitscore:
                     79.6, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 4.3e-29,
                     bitscore: 99.7, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTRRGGRVEELGVAVVGFGWMGRVHTRAYARLPHHYPRLPLRPR
                     LIAVAEEVPGRAEEAAGQFGFATATRDWREVAADPRVRAVSVNAPNFLHRRIGVAMAEA
                     GKHLWIEKPVGLSAGDARAVADAAARAGVQGTVGFNYRNAPAVERARDLIAAGEIGAVT
                     HVRIRLFSDYAAHPDSALTWRYERERGGSGVLGDLASHGADLARFLLGDITALTADTAV
                     FVPERARPAGATAGHILTGGAERGLVENEDYVGCLLRFASGARGVLEACRVSVGEQNAY
                     GFEVHGTSGAVFWDFRRMNELAVSRGTAIQDQPVCTVQAGPGDGEFAAFQPGAANAMGY
                     DDLKVVEAHRFLRSIAEGRPYGATLADAVRGAVVLDAMAESAASGNWVDL"
     gene            complement(7606..7950)
                     /locus_tag="GR129_RS30480"
                     /old_locus_tag="GR129_30480"
     CDS             complement(7606..7950)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676281.1"
                     /locus_tag="GR129_RS30480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_30480"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_145490660.1"
                     /transl_table=11
                     /translation="MTHSFALHIPDADLEPEPLDPEQIVSGNPEVTGKVLWESADGRQI
                     RGIWQITPGVVTDTEADELFVVVSGSATIDVEDGPTLRVGPGDMAVLRAGDRTTWTVHE
                     TLRKAYAINL"
     gene            8082..8618
                     /locus_tag="GR129_RS30485"
                     /old_locus_tag="GR129_30485"
     CDS             8082..8618
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676282.1"
                     /locus_tag="GR129_RS30485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_30485"
                     /product="hypothetical protein"
                     /protein_id="WP_159706713.1"
                     /transl_table=11
                     /translation="MADSTAADAHGQVAEGPRPGGHSTREALLFGGVYGAVLASSMVAA
                     LTRYGTSTPATRRYDALWLLVTALASALAHGYAHYIAERVPHRRWDGLRALRNEWPLVA
                     AVAPTVLLLAGAGWGWWPAKGVEYPAFTLNVLILFTLGLTTARQAARPWPAAVLMGLGD
                     ALLGLVVVVANAFIK"
     tRNA            8702..8775
                     /anticodon=(pos:6865392..6865394,aa:Pro,seq:ggg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="GR129_RS30490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="GR129_30490"
                     /product="tRNA-Pro"
     gene            8702..8775
                     /locus_tag="GR129_RS30490"
                     /old_locus_tag="GR129_30490"
     misc_feature    complement(9201..9216)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.6"
                     /tool="antismash"
     misc_feature    9204..9219
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.46"
                     /tool="antismash"
     misc_feature    complement(9206..9219)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.88"
                     /tool="antismash"
     gene            9214..9375
                     /locus_tag="GR129_RS30495"
                     /old_locus_tag="GR129_30495"
     CDS             9214..9375
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031579.1"
                     /locus_tag="GR129_RS30495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_30495"
                     /product="hydrophobic protein"
                     /protein_id="WP_093680146.1"
                     /transl_table=11
                     /translation="MVPLLLVLLLALILFGAGFALKALWWIAVIVLVVWLVGFVARPKG
                     GSARWYRW"
     gene            complement(9504..9908)
                     /locus_tag="GR129_RS30500"
                     /old_locus_tag="GR129_30500"
     CDS             complement(9504..9908)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GR129_RS30500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GR129_30500"
                     /product="hypothetical protein"
                     /protein_id="WP_159706715.1"
                     /transl_table=11
                     /translation="MQGAHVRLRHRQLTAAMSFGALQRSFVPTAGTSGNDVPAAGVLVE
                     AGSLDPPGEFGDGCGEDGVNRARMLPPVAGAVMPCFFRAVSRSRSNGDVRPGRLTCLEV
                     RGSRALTAAAPACASLYPRSCISQEPCENI"
     gene            complement(10001..11986)
                     /locus_tag="GR129_RS35430"
     CDS             complement(10001..11986)
                     /NRPS_PKS="Domain: oMT (71-188). E-value: 1.9e-10. Score:
                     31.2. Matches aSDomain: nrpspksdomains_GR129_RS35430_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="GR129_RS35430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_201300713.1"
                     /sec_met_domain="T1TS (E-value: 1.8e-42, bitscore: 144.9,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQDTPAAIPVVPISGPTPDPYQAAVERVYQDPPDRWRPVIGEAMW
                     FQFGVYDRGTSLDEAGARHFEIQLDLAGIEPPRRVLELGPGWGTATSYLATRFPNCPRL
                     DIVNVSRPQLDHAARRLARAGLAGRVNLYLCAARDVDRLPDPGEHYDLVLLRGAIVHLS
                     PEILEETLAGLARRMSPGGTVVISEHTYADLDRYRSAIPDPDDRLASGHRKTVTDLTRA
                     LDRHGFVLRDLRQLPSAGDSIRWLTDIGANVARHYPGADRPRVFAELADHARNWSSALR
                     TGQVAVSSLIATLGPATRSDQSRRTRAVMPSFGTTVHLPPVELTLPVLRHPGGDEAERR
                     TRIADQPYLEAHYGNAEAIAAFAAHRVPVLASLCWPHAEGDRIFHLQRALEHIAMLDDE
                     FARPDVLDNDDQCAVLREDHLNVLDGAAPRAGAPLAKLFSEVLASVLADVRPAAGARLV
                     TAVRKQIENLAARPARQVDALSLDQYLVLRRVDFFLDWMAALTEYALGIDMSGGPAGHP
                     DLTALRDTAFDLTVLFGDLYSLRKEAAERDPLNAVWLVMRDEHLDLQEAVDALAGRCEV
                     LQRHLVGIRDRILGSALGEHAAVRRYVPEIVHLHTGICEFHRVSKRYQGLGFSGSRFDS
                     GDLTIEPYRTPASIADQERRHRPFDS"
     aSDomain        complement(11423..11773)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GR129_RS35430_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="1.90E-10"
                     /label="GR129_RS35430_oMT.1"
                     /locus_tag="GR129_RS35430"
                     /protein_end="188"
                     /protein_start="71"
                     /score="31.2"
                     /tool="antismash"
                     /translation="AGIEPPRRVLELGPGWGTATSYLATRFPNCPRLDIVNVSRPQLDH
                     AARRLARAGLAGRVNLYLCAARDVDRLPDPGEHYDLVLLRGAIVHLSPEILEETLAGLA
                     RRMSPGGTVVISE"
     gene            complement(12000..13184)
                     /locus_tag="GR129_RS30510"
                     /old_locus_tag="GR129_30510"
     CDS             complement(12000..13184)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="GR129_RS30510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_30510"
                     /product="cytochrome P450"
                     /protein_id="WP_201300714.1"
                     /sec_met_domain="p450 (E-value: 5.2e-20, bitscore: 70.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDRNSPPIFGDDFARDPYRPLAALRARAPAHKVLTPDGTGLWIT
                     TGYQDTRAVLDDPTMGKDADGLRAALKRPGTVHEIDRMIAFTDPPEHTRLRRLIVSAFT
                     TARVAALRPRIESVAERLVHRMRRADGPADLIADFAVPLPFTVICELLGVPNEDRPGFR
                     AAWSRLRSAASGTTAHTAAANKMAEVLSRIVRAKRGEGTDDLLAALVNAPGDGERLTRT
                     ELVAMAYALLVAGHETTANLIGNGTLCLLTHPQQYDLIRTDAGLVPGAVHELLRYESPV
                     YLATHRFTTVPVQLGHVTVPAGEVVLAGLGPANRDPRRFPDPDRLDITRTGGGHLSFGH
                     GIHRCLGAPLALLEAEVALTVLPALRLAVPPDRLDWHTTTVFRGLNHLPVTLAT"
     misc_feature    complement(12492..12494)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(13110..13112)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(13219..14142)
                     /locus_tag="GR129_RS30515"
                     /old_locus_tag="GR129_30515"
     CDS             complement(13219..14142)
                     /EC_number="2.1.-.-"
                     /NRPS_PKS="Domain: oMT (86-206). E-value: 2.9e-11. Score:
                     34.0. Matches aSDomain: nrpspksdomains_GR129_RS30515_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006350397.1"
                     /locus_tag="GR129_RS30515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_30515"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_159706719.1"
                     /transl_table=11
                     /translation="MDGKSKTTPEYSVVRGGVLDPYEEKVVRTYEDDPADWLKVLGEHL
                     LFEWGVYNHPDSPRPVSLDEAGIRFFERQLELAGLTATSRPPLRRILDLGCGWGYIMRD
                     LADRFPECPLIDGINISPQQLDYCARYLAGHRLTDRTRLYLCNGRDVDLIPDRGHPYDL
                     VVARGVFTHFPRDTYETCLAALARRTAPGALLVISDTLFKSPEGYESAIPDEVDRLACG
                     NRKSPAYFAGTIEGAGFTIEDMRVLPSNTDVAHWFLETRSNIETWFPDGVTGALEDLRV
                     TALNMSVALLTDQVSAYSVVARRDER"
     aSDomain        complement(13525..13884)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GR129_RS30515_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="2.90E-11"
                     /label="GR129_RS30515_oMT.1"
                     /locus_tag="GR129_RS30515"
                     /protein_end="206"
                     /protein_start="86"
                     /score="34.0"
                     /tool="antismash"
                     /translation="PLRRILDLGCGWGYIMRDLADRFPECPLIDGINISPQQLDYCARY
                     LAGHRLTDRTRLYLCNGRDVDLIPDRGHPYDLVVARGVFTHFPRDTYETCLAALARRTA
                     PGALLVISDTLFKSPE"
     misc_feature    complement(14262..14271)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     misc_feature    complement(14294..14309)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.54"
                     /tool="antismash"
     gene            complement(14690..14983)
                     /locus_tag="GR129_RS30520"
                     /old_locus_tag="GR129_30520"
     CDS             complement(14690..14983)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GR129_RS30520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GR129_30520"
                     /product="hypothetical protein"
                     /protein_id="WP_159706721.1"
                     /transl_table=11
                     /translation="MRRLATTLGVLGASVALTLGATQSASAANGVLIFNGGRWENPTGC
                     HASNWPGDPATIVNATDSIAYVYSDLACKDLVDILLPTYVRTVPHAWSVAFY"
     misc_feature    15087..15101
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.28"
                     /tool="antismash"
     misc_feature    complement(16332..16347)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.15"
                     /tool="antismash"
     misc_feature    16558..16573
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 20.94"
                     /tool="antismash"
     gene            16647..17129
                     /locus_tag="GR129_RS30525"
                     /old_locus_tag="GR129_30525"
     CDS             16647..17129
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GR129_RS30525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GR129_30525"
                     /product="ricin-type beta-trefoil lectin domain protein"
                     /protein_id="WP_159706723.1"
                     /transl_table=11
                     /translation="MSKKCIGRAVMTVAAVPALVLAVSTSAHADSRVSWQDAATGGCLR
                     TYSYDYHTVDTDAGAGLNCFTGNNQNTNWIDSQSNLENPDGAWTEKSGGRCLTAYGNSV
                     YIESCGTANYYEQWYEKWNGKTWNLVNRQSGYCLDSNSSGNVYAQPCNGGNYQNWK"
     gene            complement(17855..18847)
                     /locus_tag="GR129_RS30530"
                     /old_locus_tag="GR129_30530"
     CDS             complement(17855..18847)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024039.4"
                     /locus_tag="GR129_RS30530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_30530"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_159706725.1"
                     /transl_table=11
                     /translation="MNVAHRVGLPRGEFGHLLGLAPEHLGDDLCRPPAATINRIAELTV
                     AHAPWTDVSQLLAQQSTVGALGVWDYLITCAATPLEGIKDAAASFAVVADPATETLTVT
                     EDGDHVTIGHLNHADLANQAACAIRGFALGLYRQRLSQAAGRPVTPLRVTLTTQAPRRH
                     DTLTELYGTRAIDFEAPASSLTFLASDLETPNPLTQPGLPRVLRQVAEQQLTTATPLYD
                     WLHLFRRTLSFAHAEGAPTLAAVAQRMTISIRTLQRRLEDHGTTWNTELEALRRTQITH
                     LLQKTDYGVDAIAARTGYKDGRSLRRAVHRWYGTTPSALRGTNSSSSSG"
     gene            complement(19494..19850)
                     /locus_tag="GR129_RS30535"
                     /old_locus_tag="GR129_30535"
     CDS             complement(19494..19850)
                     /GO_function="GO:0042314 - bacteriochlorophyll binding
                     [Evidence IEA]"
                     /GO_process="GO:0019684 - photosynthesis, light reaction
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018849441.1"
                     /locus_tag="GR129_RS30535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_30535"
                     /product="PRC-barrel domain-containing protein"
                     /protein_id="WP_159706727.1"
                     /transl_table=11
                     /translation="MTENMWDYTPTAGHTPDADLTGYTVEATDGHIGKVDKHSNDVGSQ
                     YIVVDTGVWIFGKEVLLPAATITLIDHEARTVSVARSKEQIKSAPEFDKDKHLGDPAYR
                     DQISGYYGAGGPGH"
     gene            complement(20042..21805)
                     /locus_tag="GR129_RS30540"
                     /old_locus_tag="GR129_30540"
     CDS             complement(20042..21805)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055: pyruvate oxidase/decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006377677.1"
                     /locus_tag="GR129_RS30540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_30540"
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="WP_145490683.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.4e-48, bitscore:
                     163.4, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.5e-39, bitscore:
                     133.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRTVARVIVDALSELGVRQVFGVVGDALNPVTDAIRETENLEWV
                     GCRHEEAAAFAASAQSQLTGTLGVCMGTVGPGSVHLLNGLYDAAKSHAPVLAIAGQVPL
                     AELGSDYFQEVDNDALFSDVAVFRATITSPDQLPQMLETAVRTALGRKGVAVLTVPGDL
                     GERELTADRPARFSLNPPLSRPDDEAVRHAAELLDGSERITMLVGQGARAARADVLALA
                     DRLAAPMVLTLKAKAGFEGDTNPFQVGQTGLIGNPAAASALQDADTLLLLGTDFPYRDW
                     YPEGRKVIQVDTEATHIGRRVPVDIGLVGDTGATVRDLLERLDTPPAGSDGARDRSHLE
                     KARKRFDQWRAGQARLADPGHDKGVVGRIRSALDNRSHDIRPEALAAVVDRVAADDAVF
                     TSDTGMATVWLSRFVEMRGERRLIGSYNLGSMANAMPQALGAQILDRERQVVAFCGDGG
                     LSMLLGDLMTLKTYRLPVKLVVFDNRRLGMVKLEQEQVGLPEFGTVLDNPDFAAVAEAM
                     GITGIRVTDPGDLDAAVRRAFSTSGPVLLDVLTNPDEIAVPAKPTVEQGWGFAVAKVKE
                     VVRSHGDSGGH"
     misc_feature    complement(21816..21831)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.97"
                     /tool="antismash"
ORIGIN
        1 atcgggcagc agggacgtga agtcctcgac gatctcgacg cgtgcccccg gccaggccgc
       61 gaacttgcgc agcttgctgc gggcgttgcg ccgcggcttg gcgggcagcg cgcggacgta
      121 cgcctcgaac gactcgtacc cgagccgcag ttcggtgtcc ggcatgctgc gcgtgaagaa
      181 gcacccggcg cgctccaact ccggtcgcag aagggcgagt tcccggtcgc cgaaatcctt
      241 gaacaccacg gtcccgagcc cggaccaggc ggccacgtcc ccggccgccg ccaccagcgg
      301 tcgtacggcc tccggcggca gcggtcccgc cgccgcgatg tggccctggc ccagcaggtg
      361 gccgcagaac agcatgggca cgcgcagcag cccggggcac acggcgcgca gcgggcgcag
      421 cagccggcgt tcgcgcggcc ccaccacgtc gtccaggcgc agcccgggaa agaggcacag
      481 cggcagcacg gccaccaact cgccgtcccg gcgcagcagc agatagcggt agccctcggg
      541 gccgaggcgg ccgcgttcca tcgccgcgaa cacaccctgg gcccacagcg gatcgtccgc
      601 cggggccagc ttccgccaga cgtccggcgg cacggcgtcg acggtgtcgg cgatctcgac
      661 ccggtaggac gcccgcgcgg gcgacggtgc gcccggccgc ggtgccgcac cgtgctctcg
      721 cctcatgagt gcctcctcgg cggggtggga tcgagggccg gagcccctgc gcgcatcgcg
      781 tcgctcagcc gatgcgcagc cgggcgccgt cgaggtgctc ccgcagcggc ccggccatgc
      841 gggcgcgcga cggcggatgg aagccgagcc cggccgcggc cgaggccaga taggtgccgt
      901 cgggcgagcc gatgaacgcc atcccgccga gggcggacag acagcggggc gccgtgcggg
      961 cgatggtgtc ctgcgccgcg taccgggcgt gcagcgcccg caccagcagc gtgtcgtccc
     1021 atgcctcggt ctccatggcc atcgccacgg cctccacggc gagcatcgcg gcctcgacgt
     1081 cgaccaggaa cggcgtcgga tcgccgccga agccacgggg tttggccagc acccgttcga
     1141 ccagggcgct gaccactccc aagtaccctg cggtcagcag gagttcgaac cagaggaagc
     1201 ccgcgacatt gagcgagtcg ggcaccgcgt cggccgtgac ctccgtggtg acgaccatct
     1261 gcggatcgag ttccacctcg gtgagcacca cctcgtcgct ctcggctccc gcgagcaccg
     1321 ggctgttcca gaacggccgc acggagagcc ccggggtctt cgccggtacg atcgccaccg
     1381 cgaggcgtgc caccccgtcc gcgccggtga gcgtgacgga ggcggtgagc aggtccatcg
     1441 accgggacag gctgcacggt ttcttgctgc cgttcaacac cacgcggccg tcccggagtt
     1501 cggccctgat ggccgggcgc aggatgttct ggccggtgtt gccctccgcg aacccggagg
     1561 ccagcagcag ccgttccccg gcgacggcgg tcagcagcag accctccatc ccggtgccgt
     1621 gcctggcggt ctccaccaga ccggcgaccg agaagtgatg catggtggtg gcgaccgcga
     1681 gggacgggca gcgggcgccg acggcccgct gcgcccggac cgcctggagc acggtggccc
     1741 cggcaccgga gtgctcggcg ggcaccagca gccccgggcc gcccgcctcg cggaacgcct
     1801 cgatcgcggg gctcggcgcg cgctccagct cggccagcgg atgcgcggcg agcgcggcgt
     1861 ccagaccggg gagcagccgg tcgagcacgg cgcgttcggt gtgcaggaag ttcacggacg
     1921 tcccttctgt gggccggggc tccgggcggg tgcgctcagc ccgaggtgac gaggggcagc
     1981 cgggtgaagg cccgcaggct gatgctgtcc cggcgcaccg gcggccgggc gtgcgccagt
     2041 ccggggaagc gcgccagcaa ctgccgtacg acggcggccc cttcgagacg ggccagggcg
     2101 gcgcccaggc agtagtgggc gcccgcgctg aagctgagca cccggatgtc gggccgcagc
     2161 acgtcgaagg tgtcggggtc cggatgccgg gcggggtcgc ggcccgcggc ggcgagcacg
     2221 gtggtgatgt tgccgccctg ggggatcgcg acgccgccca cggtcagcgg gcgggtggcg
     2281 atccgctccg tcatccgcac cggtgtgtcc cagcgcaggg actcctccac gccgttgggc
     2341 accagggcgg ggtcctcgcg cagcagtgcc agctggtcgg gatggctgag cagggcgtgc
     2401 acggtcaggc cgagcaggct ggtggtcgtc tcgaagccgg ccacgaacac cagcagcagc
     2461 atgtccagga gttcgctctc ggcgagcctg ccgtcgtcca tctcgcgcac cgcgagcagc
     2521 gcggagacca gatcgtcggc gggtctgcgc cggcgcaggg cgatgagtcg ggcgaagtag
     2581 ccgcgcaggg cggtcacggc ctcgtcggcg cgcttccagt cctcgtcggt gcgcaccggc
     2641 tccagcagtc ggctggcgtc ctgcccgtag tggtggaagc ggtcctggtc cgcgtgcggg
     2701 accccgatca gatcgcccac gacggccacg ggcagcgggt agccgaccag ttcctggaag
     2761 tcggccgcgc cgccgtcgcg ggtggcgtcg gcgaaccggt cgaggagtgc cgcggtggtg
     2821 gtctcgatgc gctccgtgag gacggcgatc cggcgggcgc tgaagcggtc ggccaccagc
     2881 cgccgcagcc gtacatggtc ggtgccgttg gcgcgcagca gcgaggaata gaagaacacg
     2941 gcggccggat gttcccgcca gtcgggcaac tccgtttcgc accaggtgag atcgggagtg
     3001 agacaggaag ggtcgctcag gacctgctgg cagtcggcga accgggtcag gaagtaggtg
     3061 tcgagcttct cgtgataata gacgggggcg atacggcgca gttcggccag ggccggatag
     3121 gggtcttcct tcccctcggc cgtgaacatc gacgaaagca gtgtttccga atccaccgtt
     3181 gcggcctttc cggccatccg gtccgggagc ggagtggcac gtcgtcagta tgtccctcag
     3241 ctggtccgac tgccatgccg gtgaattgtc cggccaatta tgatccacct ctggccggat
     3301 cccataaggg gcgtgaaata cgcgccctct tcaccacccc ggagtgcgac ggggtggtgc
     3361 aagaaggtga attatataag tcatataagc ggtcttcggg gtcggataat ccagagaccg
     3421 gaaatggacc gctcttctcg ctcgggctcg cgcacgtcgg taccgctcgt ggtcatggcc
     3481 accgcgggca cggcggacac ccccggctga ccgccgcccc ggtcgcccgc caggcgcccg
     3541 gcgacacctt ccggggcacc aggggcggca tcaagctcgt ctgctccgcc gagccggacg
     3601 cccttgagaa cgcgctcggc aaggcggagc gggcggacat cccggtggtg ggcccgaact
     3661 ccggacaggc cgaccggaag cggttcgggc cgctggagtt cttcgggcgg gacgaaagcg
     3721 tggcgggcga ggcgttcggg aacaagctga acacgaccgg cgccgaactg aacaaggatc
     3781 tcgtgaaggc cgtacggaac ggcagtatcg agtccgccgt agccgccgcc cgcggtggca
     3841 tcgcccacct cggcgacacc tttcccgaag ggaccacctg atcatgccgc acgtactcga
     3901 ccgcgtccgg gtcggctccg cccccgactc ctggggcgtc tggttccccg acgacccgcg
     3961 gcaggtgccc tgggaacgct tcctggacga ggtcgccgag gccggctacg cctggatcga
     4021 actcggcccc tacggctacc tgcccaccga ccccgcccgg ctcaccgagg aggtggcccg
     4081 ccgcgacctc aaggtctccg cgggcacggt cttcaccggc ctgcaccgcg gccccgccgt
     4141 ctgggccgac acctgggccc atgtctccca ggtcgccgcg ctcacccagg cggtgggcgc
     4201 ccggcacctc gtggtgatcc cgtccttctg gcgcgacgac aagaccgccg agatcctgga
     4261 gccgtccgag ctgaccgccg agcagtgggg ccacctcgcc cggggcatgg aacggctggg
     4321 ccgccaggtg aaggagacgt acggcctcga catcgtggtg cacccgcacg ccgacaccca
     4381 tatcgacacc gaggcccacg tcgaacgctt cctcgacgcg accgactccg gctcggtcgg
     4441 cctgtgcctg gacaccgggc actacgccta ctgcggcggc gacagcgtca ggctgatcga
     4501 gacgtacggc gaacgcatcg gctatctcca tctcaagcag gtcgacccgg ccgtgctcgc
     4561 cgaggtcgtc gcgcgcgagc tgcccttcgg tcccgccgtg gcccggggcg tcttccgcga
     4621 accaccgcac ggagtaccgg agttgggccc cgtgctggag gcggcgcaga agctgggcgt
     4681 ggacctgttc gccatcgtgg agcaggacat gtacccgtgc gcgccggaca agccgctgcc
     4741 gatcgcggag cggacacgaa ggttcctgcg gtcctgcggg gcgtgaggag gggcacccgc
     4801 cgcgtcgtcg cggacggcgc gcgtacgtcg tacgacccgt cgcgcgtcct cgccgcgccg
     4861 gtccggcgct gccggacatg acgcccgaga ggcgggcgtc gttcctgcgc aaccctgacg
     4921 gattcgcgcc agacgcggcc gggaaccaac cgggggcacg tgggcgttgt tgaggtgaac
     4981 gggggcgccc gcgcagacgg gaggacgagg atgacacacc gtacggaacc ccggaacacg
     5041 gcacaggaca ccgccgacgc ggcggcccgg cgccgggaac gcttcggcac cctgcccgag
     5101 cggatacgtc ccgaggacac ggtcgagacc agcccggcca cgctgccgga cccggcccgc
     5161 gaccggtatc acgcggacga gtggctggtg cggtactgcg gctgaggaag gccccggtac
     5221 cgcgtccgtc agacctgccg cacctccgcg accgtcaccg ggcggtgctc ggcgcgggag
     5281 agcgtgcagg cctcggcgat ccagcccgcc tccagggcgt cctcgacggt gcacggggac
     5341 gtcctggtgc cggccaccac ctcggtgaac gcggtgagtt cggcgcggta ggcgtcggcg
     5401 aaacggtcca tgaagaaggc gtgcggggtg ccggacggaa agccggcccc gggttcggcc
     5461 gagcgcagcg gcaaccgctc gtccaggccc acggcgatgg cgtcggcgaa gccgtgcagc
     5521 tccatgcgga cgtcgtagcc ccggccgttg tgacgcgagt tggagaccag cgcgatcgtg
     5581 ccgtcgtcca gggtgaggac cgcgcccgcg gtgtcggcgt caccggcccg cgcgatggga
     5641 acggcgccgc ggttgccgcc gaccgcgtac acctcggtga cctcgcggcc cgtcacccac
     5701 cggatgatgt cgaagtcgtg caccgagcag tcccggaaga tgccaccgga ggcggcgacg
     5761 tacgcggccg gcggcggtgc cgggtccagc gtcgtacagc gcacggtgtg cagcgccccc
     5821 aactcgcccg agcgcacggc ggcccgcgcg gcggcgaaac ccgcgtcgaa gcggcggttg
     5881 tagccgatct ggaccggcac cccgctgccg cgcacccggt cgcgcagcgc cacgccctcc
     5941 gccatggtgc gggccaccgg cttctcgcag aagaccggga cacccgccgc cacaccggcg
     6001 cggatcagcg cgggatgggc gtccgtggcc gccgccacga ccagggcgtc caccccggct
     6061 gccagcaggg cccccggcga gtccgcgacc tgtgccccga accgctcggc ggcggccttc
     6121 gcggcgtccg cgagcggatc ggcgaacacg agcgatgcga cggcgtcgag cccggagagg
     6181 gtctcggcgt ggaagacgcc gatgcggccg aggccgagga ttccgatacg catgggtgtt
     6241 gccgctcctc aggggttcgg acgaaagggg cgaaaggtca cggggtggtc gctcaacctg
     6301 cctacagatc gacccagttg ccactggccg cggactcggc catcgcgtcc aggacgaccg
     6361 cgccgcgcac cgcgtccgcg agcgtcgcgc cgtacggtct gccctcggcg atggagcgca
     6421 ggaaccggtg ggcctcgacg accttcagat cgtcgtagcc catcgcgttg gccgcgcccg
     6481 gctggaacgc ggcgaactcg ccgtcgcccg ggccggcctg cacggtgcac accggctggt
     6541 cctggatggc cgtgccccgg ctgaccgcga gttcgttcat ccgccggaag tcccagaaca
     6601 ccgcgccgct cgtgccgtgc acctcgaagc cgtaggcgtt ctgctcgccg accgagaccc
     6661 ggcacgcctc caggacaccc cgggcgccgg aggcgaagcg cagcaggcag ccgacgtagt
     6721 cctcgttctc caccaggccg cgctcggcgc cgccggtgag gatgtgaccg gcggtggcgc
     6781 cggccgggcg ggcgcgctcg gggacgaaga ccgcggtgtc ggcggtcagc gcggtgatgt
     6841 cgccgagcag gaagcgggcc aggtcggcgc cgtgcgaggc cagatcgccg agcaccccgc
     6901 tgccgccgcg ctcgcgctcg tagcgccagg tcagggcgga gtcggggtgg gcggcgtagt
     6961 cgctgaacaa ccggatgcgc acatgggtga cggcgccgat ctcacccgcg gcgatcagat
     7021 cgcgggcccg ttccacggcg ggcgcgttgc ggtagttgaa gccgacggtg ccctgtaccc
     7081 cggcccgcgc ggcggcgtcc gcgaccgcgc gggcgtcccc ggcggacagg cccaccggct
     7141 tctcgatcca caggtgcttg cccgcctcgg ccatcgccac cccgatcctg cggtgcagga
     7201 agttcggcgc gttgacgctg accgcccgca cccggggatc ggcggccacc tcccgccagt
     7261 cgcgggtcgc ggtggcgaaa ccgaactgcc cggcggcctc ctcggcccgg cccggcacct
     7321 cctcggcgac cgcgatcagc cgcggccgca gcgggagccg ggggtagtgg tgggggagac
     7381 gggcgtacgc ccgggtgtgc acccggccca tccagccgaa cccgacgacg gcgacaccca
     7441 gctcctccac cctgccgcct ctccgcgtca gcaccccggg accggtccac cgcccccgcc
     7501 cggccacctt tgtcctgaca tggtggcgct gtcaacgccc cgaacggggc gggatgtcga
     7561 gatcgccggt ttcggtgcgc cgcctccggc agttccgcga gtgccctaca gattgatggc
     7621 gtacgccttg cggagcgtct cgtgcacggt ccacgtcgta cggtcgcccg cgcgcagcac
     7681 cgccatgtcg cccggcccga cccgcagcgt cgggccgtcc tcgacgtcga tcgtggcgga
     7741 gccgctgacc acgacgaaca gctcgtcggc ctcggtgtcg gtgaccacgc cgggggtgat
     7801 ctgccagatc ccgcggatct gccggccgtc cgccgactcc cagagcacct tcccggtgac
     7861 ctcggggttc ccggagacga tctgttccgg gtcgaggggc tcgggttcga ggtcggcgtc
     7921 gggaatgtgg agcgcgaagc tgtgcgtcat gggcccgacc ctaacggggc ccgtgccccg
     7981 gccaccgtcg acagagtgtg cggcatcggg cctggtcgcc ggacacttcg tcgggccgcg
     8041 cggactggcg ggcgcgcggg ccgggggtga tcgtggaaga catggccgac tcgaccgcgg
     8101 cggacgccca cggacaggtg gcggagggac cgcgccccgg cgggcacagc acccgcgagg
     8161 cgctcctctt cggcggggtc tacggcgccg tcctcgccag ctcgatggtc gccgccctca
     8221 cccgctacgg caccagcacc cccgcgaccc gccgctacga cgcgctgtgg ctgctggtga
     8281 ccgccctcgc ctccgccctg gcccacgggt acgcccacta catcgccgag cgcgtcccgc
     8341 accgccgctg ggacggcctg cgggcgctgc gcaacgagtg gccgctggtc gcggccgtcg
     8401 caccgacggt cctcctgctc gcgggcgcgg gctggggatg gtggccggcc aagggcgtcg
     8461 aataccccgc cttcaccctg aacgtcctga tcctcttcac cctgggcctg accactgccc
     8521 gccaggcggc ccgcccctgg cccgccgccg tcctcatggg cctcggcgac gccctcctcg
     8581 gcctggtcgt ggtcgtcgcc aacgccttca tcaagtgacc cgcccccgat gtcagcgggc
     8641 acccgcgcgc atacggtagt gttgacctgc gtgatcacgc gatacaccgc gtgggccgca
     8701 tcgggacgtg gcgcagcttg gtagcgcact tgactggggg tcaaggggtc gcaggttcaa
     8761 atcctgtcgt cccgactcga cagagtcgca gatcaggggc ggtttcggag acatccggaa
     8821 ccgcccctga tcatttttgg ggaccagatg gggttcagcg ttccttgacc cgtgtcagcg
     8881 ggtgaggaca gtggggccgg gaagggccgg gaagggagcg ggggactcgc ggcagtcacg
     8941 taggactgcg gtggagatgc gtcctccgcc gtgtgccggt gaacatgcgc ggccacgcgg
     9001 tcgcgcccgg catcgtcgag tccctccagt aaaacctcga accagctcat ggagtgcccg
     9061 gactcatccg catgggcgac gaagggccgc ccggagcaga cccgtgtcac tgcgacggtc
     9121 aaccccgtgg gcgaccggat gtagtaatgc ggtcggtaac ctgggattgg agggggagat
     9181 gccgggcaca aggtggcccg gaggttgata atcatggttc ccctgcttct cgttcttctg
     9241 ctcgctctga tcctcttcgg tgccggattc gcactcaagg ccctgtggtg gatcgccgtc
     9301 atcgtgctcg tcgtgtggct cgtcgggttc gtggcccggc ccaagggcgg cagcgcgcgc
     9361 tggtatcgct ggtaaagccg actgccgaca gtcggtagga gcattactgc gggccccacc
     9421 cccacccggg ggcggggccc gcggatgcat gtcgtggatc ggaagccgtt accggctgac
     9481 ccggacgccg ccaacggttt acgtcaaatg ttttcgcagg gctcctgtga aatacacgaa
     9541 cgcgggtaga gggatgcgca tgccggggcg gctgccgtga gcgcacggga accgcgcacc
     9601 tccagacacg tcagccgtcc cggtctcacg tcgccgttcg aacgacttct tgagacggcc
     9661 cggaaaaagc acggcatgac cgccccggcc accggcggca gcatccgcgc ccggttgacg
     9721 ccatcctcgc cgcagccgtc cccgaactcg ccgggcgggt ccaggctgcc ggcttcgacg
     9781 aggacaccgg ccgccgggac gtcgtttccc gacgtcccgg ccgtcggcac gaagctgcgc
     9841 tggagcgccc cgaagctcat cgcggcggtc aactggcggt gccggaggcg aacgtgcgcg
     9901 ccctgcacgt cctggcgccc gcgccgtgaa ggccggcccc gccgcggcgg ccgccgcccc
     9961 gggcctcgca ccggcccggc gtgagcactc gtcggcgcct tcaggaatcg aagggtcggt
    10021 gtcgtcgctc ctggtcggcg atggaggccg gagtgcggta cggctcgatc gtcaggtcgc
    10081 cggagtcgaa gcgggatccg gaaaagccca gcccctggta gcgcttgctc actcgatgga
    10141 actcgcagat tccggtgtgc aggtgcacga tctccggtac gtaacgccgc acggcggcgt
    10201 gctcgcccag cgccgacccg agaattcgat cgcggatccc gacaaggtgg cgctgcagca
    10261 cctcgcacct gcccgcgagc gcgtcgacgg cctcctgcag atccaggtgc tcgtcgcgca
    10321 tgacgagcca gaccgcgttg agggggtccc gttcggccgc ctccttgcgc agggagtaga
    10381 gatcaccgaa caggaccgtg aggtcgaaag ccgtgtcccg cagcgccgtg aggtccggat
    10441 gcccggccgg tccgccgctc atgtcgatgc cgagggcgta ttcggtcaag gcggccatcc
    10501 agtcgagaaa gaagtcgact cggcgcaata ccaggtactg atcgagactg agcgcgtcca
    10561 cctggcgtgc cggccgggcg gccaggttct cgatctgttt ccggacggcc gtgacgagcc
    10621 gcgccccggc cgccgggcgg acatcggcca gcacggaagc gagcacctcg gagaacaact
    10681 tcgccagagg ggctccggcg cgcggcgcgg cgccgtcgag cacgttcagg tggtcctcgc
    10741 gcagcacggc acactggtcg tcgttgtcca gcacgtccgg ccgtgcgaat tcgtcgtcga
    10801 gcatggcgat gtgttccagg gcgcgctgga ggtggaagat ccggtcgccc tcggcatgcg
    10861 gccagcagag gctggcgaga acgggaaccc ggtgtgcggc gaaggcggcg atcgcctcgg
    10921 cgttcccgta gtgcgcttcg aggtacggct ggtccgcgat ccgggtgcgg cgctcggcct
    10981 cgtcgccgcc ggggtgccgc aggaccggaa gcgtcaactc gaccgggggc aggtgcactg
    11041 tggtgccgaa ggacggcatg accgccctgg tccggcgcga ctgatcggac ctggtcgcgg
    11101 gtccgagcgt ggcgatcagg ctggagacgg cgacctggcc ggtgcgcagt gcggagctcc
    11161 agttccgggc gtggtcggcg agttcggcga agaccctggg gcgatccgcg ccgggatagt
    11221 gccgcgccac gttcgcacct atgtcggtca gccagcggat cgagtcgccg gccgagggaa
    11281 gctgccgcag gtcgcggagc acgaagccgt gacggtcgag cgctcgggtg aggtcggtga
    11341 cggtcttgcg gtgtccgctg gcgagccggt cgtccggatc gggtatcgcg gagcggtacc
    11401 gatcgagatc ggcgtaggtg tgctcggaga tcaccaccgt gccgcccggg ctcatccggc
    11461 gcgcgaggcc ggcgagggtc tcctccagga tctccgggct gaggtggacg atggcgccgc
    11521 gcaggaggac caggtcgtag tgctcgccgg ggtcgggcag ccggtcgacg tcccgcgcag
    11581 cgcacaggta caggttgacc cggccggcca agccggcccg agcgagccgc cgggccgcgt
    11641 ggtccagctg cggccggctg acgttgacga tgtcgagccg cgggcagttt gggaaccggg
    11701 tggcgaggta cgaggtcgcc gtgccccagc cggggccgag ttcgagaacg cgacggggag
    11761 gctcgatccc ggcgaggtcg agctggatct cgaagtgccg cgcaccggcc tcgtcgaggc
    11821 tcgtcccccg gtcgtagacg ccgaactgga accacatcgc ctccccgatg accggccgcc
    11881 accggtccgg cgggtcttgg tagacgcgtt cgacggcggc ctggtaggga tccggggtcg
    11941 gcccgctgat cgggacgacc gggatcgcgg cgggcgtgtc ctgcacggtg gtgctccctt
    12001 caggtcgcga gggtgaccgg gaggtggttc agcccgcgga agacggtggt ggtgtgccag
    12061 tccagccggt cgggagggac cgccaggcgc agtgcgggca gcacggtgag ggccacctcg
    12121 gcttcgagca gggcgagcgg ggcgccgagg cagcggtgga tgccgtgccc gaaggagagg
    12181 tgcccgccgc cggtcctggt gatgtcgagc cggtccgggt cggggaaccg ccgcggatcc
    12241 cggttggccg gcccgagccc cgcgaggacg acttcgcccg ccgggacggt gacgtggccg
    12301 agctggaccg gcacggtggt gaaccggtgt gtcgccaggt acaccgggct ctcgtagcgg
    12361 aggagttcgt gcaccgcgcc ggggacgagc ccggcgtcgg tccggatcag gtcgtactgc
    12421 tgggggtggg tcagcaggca caacgtgccg ttgccgatca gattcgccgt ggtttcgtgg
    12481 ccggcgacca gtaacgcgta ggccatggcg accagttcgg ttctggtgag ccgttccccg
    12541 tcgccgggag cgttgacgag cgcggccagc agatcgtcgg tgccctcgcc gcgcttggca
    12601 cggacgatcc gggagagaac ctcggccatt ttgttggccg cggcggtgtg ggccgtggtt
    12661 ccggaagcgg ccgaccgcaa ccgggaccac gccgcccgga aacccggccg gtcctcgttc
    12721 ggcacgccga gcagctcgca gatgaccgtg aacggcagcg gaaccgcgaa gtccgcgatg
    12781 aggtctgccg ggccgtcagc tcggcgcatg cggtgaacga ggcgctcggc gacgctttcg
    12841 atgcgcgggc gcagcgccgc gaccctcgcc gtggtgaacg cactgacgat cagccgacgc
    12901 agccgggtgt gctccggcgg atcggtgaac gcgatcatcc ggtcgatctc gtgcaccgtt
    12961 cccggccgct tgagggccgc ccggaggccg tcggcgtcct tgcccatcgt cggatcgtcg
    13021 agcaccgccc gcgtgtcctg gtaccccgtg gtgatccaca ggccggtgcc gtcgggcgtg
    13081 agcaccttgt gcgcgggggc ccgtgcgcgt aaggccgcca ggggccggta cggatcacgg
    13141 gcgaagtcgt cgccgaagat cggcggagag ttccggtccc ccacgtgaga agccaccacc
    13201 ttccgtggga gcatcggttc agcgttcgtc ccggcgtgcg accacgctgt aggcggagac
    13261 ctgatcggtc agcagggcca cggacatgtt cagggcggtg acccgtagat cctccagcgc
    13321 cccggtgacg ccgtcgggaa accaggtctc gatgttgctg cgggtttcga gaaaccagtg
    13381 cgccacgtct gtgttggagg gcagcacccg catgtcctcg atcgtgaagc ccgcgccctc
    13441 gatggtgccg gcgaagtacg ccgggctctt gcgattgccg caggccagcc ggtctacctc
    13501 gtcggggatc gcggactcgt agccctccgg ggacttgaac agtgtgtccg agatgaccag
    13561 gagtgcgccg ggagcggtcc ggcgggccag cgcggccagg catgtctcgt aggtgtcgcg
    13621 cgggaagtgg gtgaagaccc cacgggcgac gaccaggtcg taagggtggc cccggtcggg
    13681 gatcaggtcc acgtcccggc cattgcacag gtagagccgg gtacggtcgg tgagccggtg
    13741 gccggccagg taccgggcgc agtagtcgag ttgctggggg ctgatgttga tgccgtcgat
    13801 cagcgggcac tcggggaacc ggtcggcgag gtcccgcatg atgtaacccc agccgcaccc
    13861 gaggtcgaga atccggcgca gcgggggacg gctggttgcc gtgagcccgg ccagttcgag
    13921 ctgtcgttcg aagaaccgta tgccggcttc gtcgagcgac acggggcgag gggaatccgg
    13981 gtggttgtag acgccccact cgaagagcag gtgttcgccg agcaccttga gccagtccgc
    14041 cgggtcgtcc tcgtaggtgc ggacgacctt ctcctcgtag ggatcaagca caccgcctcg
    14101 gacgacgctg tattccggag tcgtcttact ctttccgtcc atgggcactc cgccgcggaa
    14161 aagcgggaca ggcggtcacc gcacttctcg tatgtcctcg ttgcttgccg cggccggtat
    14221 cggtgttctc tccgtcggct tgaatgcgcg ctgatcgatc tggccgcctt catcattttc
    14281 tggcgaggcc gtggtgatga aatcttgagc ccgaccatgg gtcaggtccg ggccgatgcg
    14341 ggcctgaggg cccggagtta ccggtgatct cgggacgtcc cggcctccgg atgcacgatg
    14401 agtcggggtc gtcatgcgac aactcggagt gtaatcccgc acgttgccgg atgccagcac
    14461 tccggccacc cggaaagcaa ggggaaccag cgggaaattc acggacgtcg aagcgttggt
    14521 ccggcgtacc aggtggctcc gcactccggg cagcgagacc ggggccgggg gagccgtcgt
    14581 ccttccagca gggccttgta cacctcgatg gcggcgaggc gggcccgctg ccgtacgcca
    14641 ggctcgcgta cggcagcggg ccgagcagta ctgccgtgag tgtcggctcc tagtagaagg
    14701 cgaccgacca ggcgtgcggc accgtacgga cgtaggtcgg cagcagaatg tcgacgaggt
    14761 ccttgcaggc caggtccgag tacacgtagg cgatgctgtc ggtggcgttg acgatcgtgg
    14821 cggggtcgcc cggccagttg ctcgcgtggc agccggtggg gttctcccag cggccaccgt
    14881 tgaagatcag aactccgttc gcggccgagg ccgactgagt cgcaccgagc gtgagcgcaa
    14941 cactcgcgcc gagtactccg agtgtggtgg caagacgccg catgcacatc tcccttgatc
    15001 cgaaccctcg gtgccgcccc gcgccagagc ggcgggacgg cacctggacg atccgagcct
    15061 gccgggcacc ccgtccgcgc cgccacaata tccaggtact tcgggacgct ggaacacgga
    15121 agcactcgtt gaccagggca gccgcaagca gcctggaacg cgggctggaa cgcctgagcg
    15181 ctccaccagc ccccatgcac ggctccacgg acgatcacat tgaaggaaac cgcccctcaa
    15241 ccggaccgcc ctgcgctcgc gggacttgga cctggacctc ggttacaccc cgtggggggg
    15301 caggcatgag gggcagcgtg gtgtccggcg tcgacccgag cccggatcgc gctggccgcc
    15361 gcgttggagg cggctcgcac cgacggcggc ggccagaaag caaaggcgaa gccgcggctg
    15421 gtccgtacgg tgtcgccggg acgggcatga gccaatgggc ctcgaagccg cgatcggcgc
    15481 gctggtcacc gagcgcgcat gtgagcttcc ggcggcggca tcctcgccga cttcgaggcc
    15541 gtccttcgac agtcgtcctg tcgcacgtgg tcccctgggt ggcgtctttg gtccctggct
    15601 cgacgacctc ccggtcctta ccgtctagaa gtgcggctct cctcgggaga agagccgacg
    15661 cctgaaggcc gatgaactct gaaggagaac aagtggattt gaaggccgcc cgcgtgacgt
    15721 catgagcaac gctcgcagcc gtcctgccga tggcccggag ggcgcgctcc tggcgccatt
    15781 tccgcaaggc cagaaagcgc ggcctggtcc ggcggcaaag cgaggcgatc tgcatatgcc
    15841 acggtccaga acatccgatc aaccgtcaca gaatgggaca cacggcgcta cgcccggggc
    15901 cgtgggcatg ctgcgggccg atccggccgt aatcgggctc gatcgcctcc gcctcggcgg
    15961 tctctccccc cccgatcgct ttggaatgaa ctacacaaag tcggaaaagt aatcatttgt
    16021 atgcgctctg catgccaaat agggaggatt tgaacttgaa gcgcatggct aagttcgcca
    16081 gcgttgcagc cgcggtgccg atgctggtgc ttgccgccag tggcgtcgcc tgccgatggc
    16141 atcgacatca gttggaccaa ccgcgccact ggccgctgtc tgtcgtggac tgacccatcc
    16201 acgagcggct tctacctcgg tacgcagccg gactcaccat ggtgcgtcaa caactacaac
    16261 aacattttct gggacgattc acagaacaac gtatcggccc agaccggtgc cttctggacg
    16321 gagaagccca cgggaaacag ccgtgagtgc ttggccgcga atgggcaggg ccaggcatac
    16381 atggagccct gtatcactcc gcacgcgaac tggaatgagc ggtggcagga gcgctgggtc
    16441 ggaaacggat tcaacctcgt caaccgctgg tcgagccagt gcctcgacgc taacagttcc
    16501 gggcaggttt agaaactccc gtgcaacggt gctcagaacc aggtttggta ctgggcccgg
    16561 accaactggt cggggctggg taggcatgac ccggtcggat ttctggtcgg gcgtcgttca
    16621 aattgaagaa tacggggaga acttacatgt cgaagaagtg cataggccgt gcggtcatga
    16681 cggtggcggc cgtacctgcc ctcgttctgg cggtctctac gtccgcgcac gctgactcca
    16741 gggtcagttg gcaggatgcc gccacgggcg gctgcctccg aacgtattcc tatgactatc
    16801 acacggtcga cacggatgcc ggcgcgggcc ttaactgctt caccggtaac aatcagaaca
    16861 ccaactggat cgactcgcag agcaacctgg agaatcccga cggcgcctgg accgagaagt
    16921 cggggggcag atgcctcacc gcctatggaa actccgtcta catcgagtcc tgcggtaccg
    16981 ctaactacta cgagcagtgg tacgagaagt ggaacggtaa aacatggaat ctggtgaacc
    17041 ggcaaagcgg ctactgcctg gacagcaatt ccagcggtaa cgtctacgcc cagccgtgca
    17101 acggcggaaa ttaccagaac tggaaataaa atcaggcagg tgagactctc gcggcggatt
    17161 caaggtcctg gaaatcgcat ccctcgggaa gtcccccagc gccgggtgac ccaggaaacg
    17221 gccgagtcca cccggacccc cgggggcccg gccatcgccg atgcggccgg gccgtgctcg
    17281 acgcggcggc tcggaccggg cgttttcaac aagtggaccg acaaggccaa cggcgacttc
    17341 acctgctacg cggagtccaa tcccagcgac cccaccgccg ccaacatcaa caactcgaac
    17401 atcgagggct ggccgactac tcaactcgac cgcggagaca gggatgtggg accctgccga
    17461 ccacaacttc cacctgcgca attcgcgcac caccggcccg aacgagaagg acttcgtctt
    17521 cgggggcgcc gggacgaggc cggtcccggg tgactcggac ggcatcggca ccgacggcgt
    17581 cggcatgtac gactgcgcga accacatcgt ctgcctccgc gacagcacca ccgcctcggc
    17641 aaagactgca ccatcagcta cggcaccccg gcgacgggga cggccggtaa agcagggcac
    17701 ccgacccctc aggcgtaccc gcactactca cagacgccat cggaatcgcg ctctgcgtca
    17761 ccgcccacga cctcccgtca tcggctgacc gtgccccggc tgacggccgc cggcacttgc
    17821 gggccgaccg ccaggtcgag ggcaggccgg ctggtcaacc gctggatgac gacgagttcg
    17881 tgccgcgcag agcggagggg gtggtgccgt accagcggtg tacagcgcgc cgcagggagc
    17941 gtccgtcttt gtagccggta cgggcggcta tcgcgtcgac accgtagtcg gtcttctgga
    18001 gcaggtgtgt gatctgcgtg cggcgcagag cttcgagctc cgtgttccag gtggtcccgt
    18061 gatcttcgag gcggcgctgg agggtgcgaa tgctgatggt catgcgttgt gcgacggcgg
    18121 ccagggtcgg ggctccctcg gcgtgggcaa aggacagggt cctacggaac aggtgcagcc
    18181 agtcgtacag gggggtggcg gtggtgagtt gctgctcggc cacctgccgc aggacgcgag
    18241 gcagaccggg ctgggtgagc gggttggggg tttcgaggtc ggaggccagg aaggtgagcg
    18301 agctggcggg ggcttcgaag tcgatggcgc gggtgccgta gagctcggtc agggtgtcgt
    18361 gccggcgggg cgcctgcgtg gtgagggtga cgcggagggg ggtgacgggg cgtcctgcgg
    18421 cctggctcag gcgctgccgg tacaggccga gtgcgaagcc gcggatggcg caggccgcct
    18481 ggttcgccag gtcggcgtgg ttgaggtggc cgatggtgac atggtcgccg tcttcggtga
    18541 cggtgagcgt ctcggtggct gggtcggcga ccacggcgaa cgaggcagcg gcgtccttga
    18601 tgccttccag cggcgtggcc gcgcaggtga tcaggtagtc ccacaccccg agggcaccga
    18661 cggtcgactg ttgcgccagc agctgggaga cgtccgtcca gggcgcgtgc gccactgtga
    18721 gttccgcgat gcggttgatg gtggcggccg ggggacggca caggtcgtca ccgaggtgct
    18781 cgggggccag acccagcagg tgtccgaact cgccgcgggg caaaccgacg cggtgtgcga
    18841 cgttcacact gaggcgggtc agcgccgcag aggccgttcc ctgatgggct ggcaatgatg
    18901 tggacacgac cagccatcat agccagggga gtcgatgcac catcgcagcg gtgggatcgg
    18961 tggcgggtgg cacgcacggc ccctcgggtg gcgcgcgcgg cccctccggt ggcgcgcggt
    19021 ccctggtcgg gtgtgctggc gctgcttagc ggtcgattcc cgaaaccatt cgagggttgc
    19081 cgcagcggta ggtgccgtgc cagagggccg ggaggatacc cgggcgtgcg gcggggatcc
    19141 catgtgtggg ccaggacctc ctcgggggtg cgggcgcggg ggccctgccc agaccgggct
    19201 gggcggcggg gggcgtgggg cggcgcgtca ccgccgcccc acgaccgccc accgcgccgg
    19261 catcggcacc ggaccccggg cggagtcctc agatcacgaa cttgtccggg gtgaacccgt
    19321 ccatccgcgg cgaacccgtc cggggtgggc ccgtccgggg cgggcgggcc cgtctggctg
    19381 gggcgggccc gtcgctctgc cgctcgacgg cgacgaaggc cgtgcggtgg accgcaggtc
    19441 gcggggatca gcgaccgtgc gggcgaagta cggtgcgacg ggcgccggac gggtcagtgc
    19501 ccggggccgc cggctccgta gtagccactg atctggtccc ggtaggcggg gtcgcccagg
    19561 tgcttgtcct tgtcgaactc cggcgcgctc ttgatctgct ccttggagcg ggcgacactg
    19621 acggtcctcg cctcgtggtc gatgagggtg atcgtcgcgg ccgggagcag gacctccttg
    19681 ccgaagatcc acacaccggt gtcgacgacg atgtactgcg atccgacgtc gttggagtgc
    19741 ttgtcgacct tgccgatgtg tccgtccgtg gcctccaccg tgtagccggt gagatcggcg
    19801 tcaggggtgt ggccggccgt cggtgtgtag tcccacatgt tctcggtcat gcctgtcctc
    19861 cgcggatgct tgtcgaggga tgcccgcgca tcccggtttc cctctcggga agctccgtct
    19921 gtccgtgaag cggatcggca aacgcctgat gccgccatcc ggggtatgcc tgcgccgggg
    19981 ctgccgtcgg cgagaccctc aacggtcgcc gacggctttc cctgcgggag acctgaagcg
    20041 ctcagtgccc gccgctgtcc ccgtggctcc gtacgacctc cttcaccttg gccaccgcga
    20101 acccccagcc ctgctcgacg gtcggcttgg ccggaacggc gatctcgtcg gggttggtca
    20161 ggacgtcgag cagcaccggc cccgaggtgc tgaacgcccg gcgcaccgcg gcgtccaggt
    20221 cgcccgggtc ggtcacgcgg ataccggtga tgcccatggc ctcggcgacg gcggcgaagt
    20281 cgggattgtc gaggacggtg ccgaactcgg gcaggccgac ctgctcctgt tcgagcttca
    20341 ccatgcccag ccgacggttg tcgaagacga ccagcttgac cgggagccgg taggtcttca
    20401 gggtcatgag gtcgccgagc agcatgctca gtccgccgtc gccgcagaag gccacgacct
    20461 gccgttcgcg gtccaggatc tgtgcgccga gcgcctgcgg catggcgttg gccatcgagc
    20521 cgaggttgta ggagccgatg aggcggcgtt cgccacgcat ctcgacgaag cgggagagcc
    20581 acaccgtggc catgccggtg tcggaggtga agacggcgtc gtcggcggcg acccggtcga
    20641 cgacggcggc gagcgcctcg gggcggatgt cgtggctgcg gttgtccagc gcggaccgga
    20701 tccggcccac gacgcccttg tcgtgaccgg ggtcggcgag ccgggcctgg ccggcgcgcc
    20761 actggtcgaa acgcttgcgc gccttctcca ggtgggagcg gtcacgggcg ccgtcggagc
    20821 cggccggcgg ggtgtcgagg cgctccagca ggtcccgtac ggtggcgccg gtgtcgccga
    20881 cgagtccgat gtcgaccggc acccggcgtc cgatgtgcgt ggcctcggtg tcgacctgga
    20941 tcaccttgcg gccctcggga taccagtccc ggtaggggaa gtcggtgccg agcaggagca
    21001 gggtgtccgc gtcctggagg gcggaggcgg cggcggggtt gccgatcagg ccggtctggc
    21061 cgacctggaa gggattggtg tcgccctcga agccggcctt ggccttcagc gtgagcacca
    21121 tcggcgcggc cagccggtcg gcgagggcga ggacgtcggc gcgggcggcg cgggcgccct
    21181 gtccgacgag catcgtgatc cgctcggagc cgtcgaggag ttcggcggcg tggcggacgg
    21241 cctcgtcgtc gggacggctc aacggggggt tcagggagaa ccgggcgggg cggtcggcgg
    21301 tcagctcccg ctcgcccagg tcacccggca cggtgaggac ggcgacgccc ttgcggccca
    21361 gcgcggtacg caccgccgtc tccagcatct gcggcagctg gtcgggcgag gtgatggtgg
    21421 cgcggaagac ggccacgtcg ctgaagaggg cgtcgttgtc gacctcctgg aagtagtcgc
    21481 tgccgagttc ggcgagcggt acctggccgg cgatggcgag gaccggggcg tggctcttgg
    21541 cggcgtcgta cagcccgttg aggaggtgga cggaaccggg tccgacggtg cccatgcaca
    21601 cgccgagggt tccggtgagc tgggactggg cgctcgcggc gaaggccgcc gcctcctcgt
    21661 gccggcagcc cacccattcc aggttctcgg tttcgcggat ggcgtcggtc acgggattga
    21721 gggcgtctcc cacgacgccg aacacctggc gcacaccgag ttcgctcagc gcgtccacga
    21781 tgacgcgggc aacggtacgg gacatgtgga tcctccggat cagacggtga aacggtcggg
    21841 gtcggcggcc tgccagtcgg ccgcccagga ctgtggtggc tcggcgagca gttgcccggg
    21901 ttcgagccac tcgtacagtt cttcgtagga gcgttcggtg tgggggtcga tgcggcggtg
    21961 gagcatgtgg gggcgcaggt ccgcgg
//
