LOCUS       NZ_CP047144            22163 bp    DNA     linear   CON 30-JAN-2024
DEFINITION  Streptomyces sp. HF10 chromosome, complete genome.
ACCESSION   NZ_CP047144
VERSION     NZ_CP047144.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. HF10
  ORGANISM  Streptomyces sp. HF10
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7814787)
  AUTHORS   Li,J., Ni,J. and Li,Y.
  TITLE     Multiple polyene macrolides produced by antifungal Streptomyces from
            gut of Macrotermes barneyi facilitates the termite-fungus mutualism
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7814787)
  AUTHORS   Li,J., Ni,J. and Li,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-DEC-2019) State Key Laboratory of Microbial
            Technology, Shandong Unversity, 72 Binhai Road, Qingdao, Shandong
            266237, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 10-NOV-2018
            Assembly Method                   :: SPAdes v. NOV-2018
            Assembly Name                     :: SDU_Sthf_5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/30/2024 05:29:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,091
            CDSs (total)                      :: 6,988
            Genes (coding)                    :: 6,640
            CDSs (with protein)               :: 6,640
            Genes (RNA)                       :: 103
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 79
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 356
            CDSs (without protein)            :: 348
            Pseudo Genes (ambiguous residues) :: 0 of 356
            Pseudo Genes (frameshifted)       :: 235 of 356
            Pseudo Genes (incomplete)         :: 154 of 356
            Pseudo Genes (internal stop)      :: 18 of 356
            Pseudo Genes (multiple problems)  :: 53 of 356
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:39:54
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6232299
            Orig. end                         :: 6254462
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP047144.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Jinfeng Ni.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22163
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="23"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22163
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22163
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12163](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12163
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            172..825
                     /locus_tag="GR129_RS27655"
                     /old_locus_tag="GR129_27655"
     CDS             172..825
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675678.1"
                     /locus_tag="GR129_RS27655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_27655"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_159706039.1"
                     /transl_table=11
                     /translation="MNGFFDLPSDLQYTYLGLVGLHLREALIPVLAGLVVALPIAQLCA
                     RFRWVYPPVLGLTTVLYSIPSLAFFVVLIDYFGQSETTVMIPLAVYSLVVLVPGIVDGV
                     RSVPQETLAAAEAMGFGPLRRYLQVQLPIAAPAIIAGLRVAVISSLSLVSVGMLIGNQG
                     ALGNMLYDANTYHRPALAVNSVLTTAVLGVLADALLVLVRRLLTPWMPRKGAAR"
     gene            822..1490
                     /locus_tag="GR129_RS27660"
                     /old_locus_tag="GR129_27660"
     CDS             822..1490
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016432011.1"
                     /locus_tag="GR129_RS27660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_27660"
                     /product="ABC transporter permease"
                     /protein_id="WP_145486557.1"
                     /transl_table=11
                     /translation="MNVLHLVHAFFGDGAHWHGYDGIPARLAEHVTYSLEALLIAAVIG
                     LPVGLVTGHYGRGGNALALIATAGRALPSFGLLVLMVLWIGLGLVPVMIPLVVLAVPPI
                     LVTTYEAVATVDPSPVDAARGMGMSEGRVLFRVEVPVALPLILSGLRTAAVQIISTATI
                     AAYVGLGGLGRYIIDGLYQRDYEKVVGGAALVAGLALVTLLLFWAAARVTVSRGVRRST
                     "
     gene            1612..2532
                     /locus_tag="GR129_RS27665"
                     /old_locus_tag="GR129_27665"
     CDS             1612..2532
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016432006.1"
                     /locus_tag="GR129_RS27665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_27665"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_145486556.1"
                     /transl_table=11
                     /translation="MTSTSQISRSIRRNRGAAAAVALAMATALLAGCSAKSGGVVVGSN
                     NFPESNLLADIYGEALKAKGIDVTYKPNIGSRETTYGLLKNGSVAVLPEYNGALLAYLD
                     PKATPKSAEETTAAIKAKLASKLTLLDPSSAQDKDSLAVNAETARKYHLTTDSSAADLK
                     AVAKDLVIGGSPEFQTRQQGLAGLKSVYGLDFKSFKALDAGGTLTQTALKKNDVQVADI
                     FSTDPTIAKEKFVVLKDPQNLFGFQNIQPVVSRTALPKKGVAALNAVSAKLDTATLLNL
                     DTQVQLQHKDPLDVAKAWLKSAGLD"
     gene            complement(2602..3057)
                     /locus_tag="GR129_RS27670"
                     /old_locus_tag="GR129_27670"
     CDS             complement(2602..3057)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675687.1"
                     /locus_tag="GR129_RS27670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_27670"
                     /product="TerB family tellurite resistance protein"
                     /protein_id="WP_145486555.1"
                     /transl_table=11
                     /translation="MALWDRVKESASQMQNQLVAKKNDLKSGAFRDASMAMCALVAAAD
                     GTVDPSERQRVAQLIATNEVLQNFPADDLRRRFDENLNKLTTDFAFGKVSILQEIAKAK
                     KKPAEARAVIQIGIVIGGADGDFDKTEQAVVREACFTLELPPHEFDL"
     misc_feature    3011..3025
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.24"
                     /tool="antismash"
     gene            complement(3156..3593)
                     /locus_tag="GR129_RS27675"
                     /old_locus_tag="GR129_27675"
     CDS             complement(3156..3593)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010034198.1"
                     /locus_tag="GR129_RS27675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_27675"
                     /product="DUF6114 domain-containing protein"
                     /protein_id="WP_186337699.1"
                     /transl_table=11
                     /translation="MADRSRPGAGRSFRSWRARRPFWGGLLLALGGGEILLTEKASLKV
                     VMHIGMQGLAGYLLPGLMALLGLLILFNPAQRLFYSIVGVLVSLGTWVTSNLGGFFIGL
                     LLGVAGSCLAFGWLPDQEPRVGRRGRRRARALAEEAGTSAV"
     gene            complement(3599..4294)
                     /locus_tag="GR129_RS27680"
                     /old_locus_tag="GR129_27680"
     CDS             complement(3599..4294)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996942.1"
                     /locus_tag="GR129_RS27680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_27680"
                     /product="DUF6230 family protein"
                     /protein_id="WP_145486553.1"
                     /transl_table=11
                     /translation="MASSPDLSSTGNTPENPESGSPSEAPSSTAAPATGRRGRVRARRA
                     AVMAVPATLVAAGLAVLTAQGALGVQFAISGMPFTVTASQLDGTGFEQFGGLDNMADGS
                     PNAGDTGGQELIVTSAIKKATLTKLCQSVDLGGTNLLITAGSGATKVSASDLTTDSTAM
                     SGDASFNHIEIGNDASTLTEANAKGPIGVFSQQADSVHIDHLRQTNYATTAGVFKLPGL
                     KLRFSDSGC"
     misc_feature    complement(4475..4490)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.09"
                     /tool="antismash"
     gene            5030..5680
                     /locus_tag="GR129_RS27685"
                     /old_locus_tag="GR129_27685"
     CDS             5030..5680
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675693.1"
                     /locus_tag="GR129_RS27685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_27685"
                     /product="Tat pathway signal sequence domain protein"
                     /protein_id="WP_159706041.1"
                     /transl_table=11
                     /translation="MRTRTLIALAGTATATALALVSAGPASAAGSVLTKGSAGGTAVAV
                     GDTLTAPLASGTSATFYSSSTGTSGVKCGTSQFTAKVTANPTAPGTATESLTGQTFSGC
                     TSNVTGVLGVGSVTIDNLPYTAAASSSGTLTVSPPSGSVIQSTVKLNTLLGSVTCVYQG
                     PSLAGKTANADNSITFTNQQFTKTSGSSLCFSTAYFSAKYAPVTDAGSSVYVN"
     gene            5991..6635
                     /locus_tag="GR129_RS27690"
                     /old_locus_tag="GR129_27690"
     CDS             5991..6635
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675696.1"
                     /locus_tag="GR129_RS27690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_27690"
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_159706043.1"
                     /transl_table=11
                     /translation="MARQLRAEQTRATIITAAADLFDQHGYESTSLSDIVAHAKVTKGA
                     LYFHFAAKEDLAHAILELENRAARRLVADLDGRGYSSLEGLMRTTFGIARLAVDDPVPR
                     AGLRLATADVKVRPPLRHPYTEWLEFAGRKFTGAVREADVHGDLDVSAAAHSLVCFFFG
                     TRVAGRFEPVGRLPRRVAEMWHLMIRGLVPVHRRPRYVTLATQLEREIRTA"
     misc_feature    6003..6005
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            6658..7854
                     /locus_tag="GR129_RS27695"
                     /old_locus_tag="GR129_27695"
     CDS             6658..7854
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010034217.1"
                     /locus_tag="GR129_RS27695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_27695"
                     /product="damage-control phosphatase ARMT1 family protein"
                     /protein_id="WP_159706045.1"
                     /transl_table=11
                     /translation="MPETPFASVILGNEPGSFPHGVLAERHPAIVRQVRDALPYGPGQH
                     RALDELLKSCAEGTVEPLPADAPDRAAWHAWGLAEYAGRSWFDVPWLWSESYFYRRLLE
                     AVGYFAPGPWRGIDPFRPVKRAELAAPETDRELAALDDLRELPEPERDRALLHGSLWGN
                     RADLGFRLSAEGAEAREPAPALVADDSERLWTLLPPGGAADLVLVADNAGRELVPDLLL
                     IAHLLAGGRIARAVLQVKPYPYYVSDAIMADVLDALERLRTAPGAAGEHGRLLRSAMAD
                     GRLTVRAHPFCCAPLPYERMPDDLRAEFAAATLTVFKGDLNYRRLVGDRRRPPTASFAA
                     ATAYFPGPVAALRTLKSEVVTGLAAATEERLVAAEGQRWRTDGTHALIQVNPGAPAAT"
     gene            complement(7826..9088)
                     /locus_tag="GR129_RS27700"
                     /old_locus_tag="GR129_27700"
     CDS             complement(7826..9088)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016645378.1"
                     /locus_tag="GR129_RS27700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_27700"
                     /product="cytochrome P450"
                     /protein_id="WP_159706047.1"
                     /sec_met_domain="p450 (E-value: 1.7e-16, bitscore: 58.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTGTAGPVPDVFDPRRYASGVPYDAYRVLRDEHPVAWQEEPEVL
                     GWPAGPGFWAVTRHADVVRVLKDSAAYSSRLGATQIRDPDPEDLPFIRRMMLNQDPPHH
                     GRLRRLVSRAFTPGRIERFAALAGERARTLLAAARERAALGDGTVDLVAAVTDEYALLN
                     LTDLLGVPEGDRRLLLRWTRRVIGYQDPDEAAPRVLDGSGKPLNPRSPAMLRDMFAYAR
                     ELAAHKRRHPADDIMTTLAADPELTGPELEMFFFLLTVAGNDTVRGAAPGGLLALAEHP
                     EPYELLRTGKAELAPAVEELLRWHPPVLTFRRTAARDTELAGRRIAAGDKVVVFHASAN
                     RDERVFAEPGRLDLARSPNPHVSFGDGPHVCLGAHFARLQLRLLYAEALRALPVLRPAG
                     PAERLVSNFINGLKSLPVHLG"
     gene            complement(9085..9867)
                     /locus_tag="GR129_RS27705"
                     /old_locus_tag="GR129_27705"
     CDS             complement(9085..9867)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (19-239). E-value:
                     9.7e-23. Score: 73.0. Matches aSDomain:
                     nrpspksdomains_GR129_RS27705_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983604.1"
                     /locus_tag="GR129_RS27705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_27705"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_159706049.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.2e-17, bitscore:
                     64.0, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 7.2e-17, bitscore: 60.5,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSFVLPHEVHGDGAHRVFAVHGWFADRSAYAAVLPDLDRTSFTY
                     VPVDLRGYGEAADAPGPYTTAQAAVDLVALADRLGWARFSVIGHSMGGAVAQRLLALAP
                     GRLRRVVGVSPVPAAGMPLSGEQGALFTDAAHKAGNRRAIIDFTTGGRRPAAWLDRMVW
                     TSFQRSDAKAFRAWLDSWAGEDFHAEVTGSEVPALAVAGELDPALTPELMRRTWLSWYR
                     HGHLVALPGAGHYAMDETPLELIRVVEDFLRADGSDEA"
     aSDomain        complement(9151..9810)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GR129_RS27705_Abhydrolase_1.1"
                     /evalue="9.70E-23"
                     /label="GR129_RS27705_Abhydrolase_1.1"
                     /locus_tag="GR129_RS27705"
                     /protein_end="239"
                     /protein_start="19"
                     /score="73.0"
                     /tool="antismash"
                     /translation="AVHGWFADRSAYAAVLPDLDRTSFTYVPVDLRGYGEAADAPGPYT
                     TAQAAVDLVALADRLGWARFSVIGHSMGGAVAQRLLALAPGRLRRVVGVSPVPAAGMPL
                     SGEQGALFTDAAHKAGNRRAIIDFTTGGRRPAAWLDRMVWTSFQRSDAKAFRAWLDSWA
                     GEDFHAEVTGSEVPALAVAGELDPALTPELMRRTWLSWYRHGHLVALPGAGHYAMDE"
     CDS_motif       complement(9577..9612)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GR129_RS27705_0001"
                     /evalue="4.00E-04"
                     /label="NRPS-te1"
                     /locus_tag="GR129_RS27705"
                     /protein_end="97"
                     /protein_start="85"
                     /score="13.0"
                     /tool="antismash"
                     /translation="VIGHSMGGAVAQ"
     gene            10001..12163
                     /gene="cyc2"
                     /locus_tag="GR129_RS27710"
                     /old_locus_tag="GR129_27710"
     CDS             10001..12163
                     /EC_number="4.1.99.16"
                     /EC_number="4.2.3.22"
                     /EC_number="4.2.3.75"
                     /codon_start=1
                     /gene="cyc2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010034221.1"
                     /locus_tag="GR129_RS27710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_27710"
                     /product="germacradienol/geosmin synthase Cyc2"
                     /protein_id="WP_159706051.1"
                     /sec_met_domain="T1TS (E-value: 1.1e-82, bitscore: 277.4,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQPFELPHFYMPFPARLNPHLDEARAHSTAWAREMGMLEGSGIW
                     DQADLDAHDYGLLCAYTHPDCDGAALSLITDWYVWVFFFDDHFLDMFKRTQDRAAGKAH
                     LDRLPLFMPIDPHAPVPEPENPVEAGLKDLWARTVPAMSVDWRRRFSVSTEHLLNESMW
                     ELSNINEGRIANPVEYIEMRRKVGGAPWSAGLVEYATAEVPAAVAETRPLRVLMETFAD
                     AVHLRNDLFSYQREVEDEGENSNGVLVLETFFGCTTQQAADTVNDILTSRLHQFEHTAL
                     TEVPAIALEHGLTPAETGAIAAYAKGLQDWQSGGHEWHLRSSRYMNKGARSDSPWRLPS
                     GPGTSAAHIGALLASAAHERLRAYSHVPHQKVGPSILPEFHMPFALELSPHLDATRRNL
                     RAWCDRMGILQEGVWDEDKLRAYDLALCSAGLDPDATPEALDLSAQWLAFGTYGDDYYP
                     LVYGHRRDLAAARLTTARLSACMPVDGEPPLVPGNAMERSLGDLWARTTAPMSTGQRRT
                     LKQAVDTMTESWVWELSNQLQNRVPDPVDYLEMRRATFGSDLTLSLCRMGRGPAVPPEV
                     YRSGPVRSLENAAIDYACLLNDIFSYQKEIEYEGEIHNAVLVVQNFFGVDYPTALGVVH
                     DLTTQRMRQFEHVVAHELPVLYDDFGLSPQARTAMDGYVDDLRNWLAGILNWHRSVDRY
                     KDAWLSRRAHGFLPDRPPVRPLLTPG"
     gene            <12333..>12572
                     /locus_tag="GR129_RS27715"
                     /old_locus_tag="GR129_27715"
                     /pseudo=""
     CDS             12333..>12572
                     /GO_function="GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431964.1"
                     /locus_tag="GR129_RS27715"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="GR129_27715"
                     /product="multicopper oxidase domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MEQWSFLDLAPIVHPMHIHLADFQLLGRDAHDVSGFDPAAGGTRA
                     PIRHDAGTAIPLAPNEQGYKDVFRVPGGQPLRVMG"
     misc_feature    complement(12611..12629)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.67"
                     /tool="antismash"
     gene            12762..13301
                     /locus_tag="GR129_RS27720"
                     /old_locus_tag="GR129_27720"
     CDS             12762..13301
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007445378.1"
                     /locus_tag="GR129_RS27720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_27720"
                     /product="PDZ domain-containing protein"
                     /protein_id="WP_159706053.1"
                     /transl_table=11
                     /translation="MEHTALRPRPLPGRGPRTGGGPRTGGGPAHHPHAASRRVRRLRTL
                     LLGVCAGTLLVLSGVGIGAVGATVLGAGQSAEPHPPAAAPPARDSGPKATLGVEAVDYG
                     SPGALVVGVHTPGPGSRAGLARGDVLLQFGGARVDTAADLAGAVARARPGSEILLTVRH
                     SGGGFQQLTVVPGVVT"
     gene            13520..14647
                     /locus_tag="GR129_RS27725"
                     /old_locus_tag="GR129_27725"
     CDS             13520..14647
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1172: methionine aminopeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019071452.1"
                     /locus_tag="GR129_RS27725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_27725"
                     /product="aminopeptidase P family protein"
                     /protein_id="WP_159706055.1"
                     /transl_table=11
                     /translation="MTGRTTTPFSAADHKARMERAARAAADAGLAGLLVAPGPDMVWLT
                     GYTPTAVTERLTLLVLAPGRDPVLVVPTLEAPDAEHSVAGEALTLRDWTDGKDPYAVTA
                     ELLDGRGRYGISDNTWGMHVLGLQRTLPDSSYAALTDSLPMLRAVKDAAEVELLAAAGA
                     AADAAFEEIRKVTFAGRRESDLGRDLAALLRRFGHSQVDFTIVGSGPNGANPHHEVGDR
                     VIRRGDMVVLDFGGLKDGYGSDTTRTVHVGEPTEEERRVHDIVREAQEAGYQAVRPGVA
                     CQDVDRAARAVITDAGYGEYFIHRTGHGIGVTTHEPPYMIEGEELPLVPGMCFSVEPGI
                     YLPGRFGVRIEDIVTVTEDGGRRLNNTGREMVTVD"
     gene            14724..15656
                     /locus_tag="GR129_RS27730"
                     /old_locus_tag="GR129_27730"
     CDS             14724..15656
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020133694.1"
                     /locus_tag="GR129_RS27730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_27730"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_159706057.1"
                     /sec_met_domain="APH (E-value: 3.2e-14, bitscore: 52.1,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQAPTPTADTVRQLVRSLLKEGPDGDGPDVRPVREGHAYTWWVG
                     TRQVLRLAPDREASARRRRELRLRALVRPHVPVAVPVSVAHADWAPGLACTLDTVVPGG
                     TAEEHEVSAAGEADLAGLLTGLRAVPVRQADALGVPRAAPRSLEALRRMAVHAAERLAA
                     ADEFDAAPMYQLTPAGAAQLAAQPGVAVLTHHGLTGERVVVSADGRVRGVLDWTEAALG
                     DPAEDIAGLAVAVGSPAAVRAATLAGYGARPCLRGLWLARCDTVLRLMDRLDDRAPGDP
                     TLLRSRLHRAWEPILLERVTDFKTAGEEP"
     gene            complement(15726..17471)
                     /gene="treZ"
                     /locus_tag="GR129_RS27735"
                     /old_locus_tag="GR129_27735"
     CDS             complement(15726..17471)
                     /GO_function="GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /GO_process="GO:0005992 - trehalose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="treZ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1297: Pullulanase, type I"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675705.1"
                     /locus_tag="GR129_RS27735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_27735"
                     /product="malto-oligosyltrehalose trehalohydrolase"
                     /protein_id="WP_159706059.1"
                     /sec_met_domain="Alpha-amylase (E-value: 2.6e-10, bitscore:
                     39.1, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQFEVWAPQADRVTLRCEGAARALARDPEREGWWKGEATAGDGAR
                     YGFALDDGPVLPDPRSRRQPDGPDGLSAVVDQERYRWRVPWPGRELPGAVLYELHVGTY
                     TPEGTLDAAADRLGHLVELGISHVELMPLCPFPGRHGWGYDGVSPWAVHEPYGGPEALK
                     RFVDRAHELGLGVVLDVVHNHLGPSGNHLPSFGPYFTDTHTTPWGAAMNLDAPGSDEVR
                     AFLVGSALAWLRDFRLDGLRLDAVHALYDTRAVHFLEELSAAVDHLAAEVDRPLFLIAE
                     TDLNNPRFITPRAESGLGLHAQWNDDFHHALHTALTGESQGYYADFARDPFAALARTLT
                     GGYFHDGTYSGFRGRHHGRPLDRARVAGHRLLGYSQTHDQIGNRAQGDRLSARLSPGLL
                     ACAATLVLTAPFTPMLFMGEEWAAGTPWQYFADHTDPGLAEAVRRGRRREFAAHGWAEE
                     DVPDPGDPATRERSCLDWSEPERVAHARMLDWYRRLISLRRDQPDLTDPDLADTKVAYD
                     GQARWLAFRRGDVRVAVNLGEEPAAIPLGSRPALVLAAWEPVEPPGADGMLQLPGESCV
                     VLSQP"
     misc_feature    complement(17631..17645)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.42"
                     /tool="antismash"
     gene            17674..18237
                     /locus_tag="GR129_RS27740"
                     /old_locus_tag="GR129_27740"
     CDS             17674..18237
                     /GO_function="GO:0051219 - phosphoprotein binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385491.1"
                     /locus_tag="GR129_RS27740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_27740"
                     /product="DUF1707 and FHA domain-containing protein"
                     /protein_id="WP_145486541.1"
                     /transl_table=11
                     /translation="MTSSFEFPTAPAPASARLSDTEREAALEVLRDGAAKGRLSHETFV
                     RRMELALAARHADELAVLVADLPRENRLSRAVFGTVEAVSGFTVRLRRAWQAERLPKLL
                     LPGPAHTRPLRIGRDPGNGLRLTHETVSRVHAELSHQGGLWILRDLGSTNGTTVNGRRV
                     IGAVAVREGDQVAFGRVAYRLSLS"
     misc_feature    complement(18240..18258)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.21"
                     /tool="antismash"
     misc_feature    18348..18364
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.06"
                     /tool="antismash"
     gene            18364..18771
                     /locus_tag="GR129_RS27745"
                     /old_locus_tag="GR129_27745"
     CDS             18364..18771
                     /GO_function="GO:0004867 - serine-type endopeptidase
                     inhibitor activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019071457.1"
                     /locus_tag="GR129_RS27745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_27745"
                     /product="SSI family serine proteinase inhibitor"
                     /protein_id="WP_159706061.1"
                     /transl_table=11
                     /translation="MTYFTRATTAAGVLLATAGLLAAGPAQAVPHPHGNRLHLTITRSG
                     LRADSGRSALLRCLPPHGHPYAAEACAELAVARGDIDRIPARKVFCPRIYSPVTATARG
                     RWNGRLVDFRRTYTNSCELRARTGSVFDLGD"
     gene            complement(18810..20063)
                     /locus_tag="GR129_RS27750"
                     /old_locus_tag="GR129_27750"
     CDS             complement(18810..20063)
                     /GO_function="GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006381321.1"
                     /locus_tag="GR129_RS27750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_27750"
                     /product="M14 family zinc carboxypeptidase"
                     /protein_id="WP_159706063.1"
                     /transl_table=11
                     /translation="MSLLPELRYPSVPELVASARALAASEPGLCALRQVGRSRAGRPLH
                     LLSVGHARRSVLVVAGAHANEPTGGSTLRVLAQRVLAEPELRSGISWHFLLCADPDGAA
                     LHVTPAPRSLLDYHLGFYRPTGAEQPEWSPSVLPPDRLPPETQALTGVIDELRPYLQVT
                     LHGTDLGGSWVQLTRDVPGLAEPFAKSAAQLHIPVETGASDAAGWPASGPGVHVMPGPE
                     TGVAYPSMPDDARHSTWYHAHRYGGLTAVVEVPMWASDLVDDPAPHPAPAAAIRRLARR
                     LLRDSLEVERVLAEALPRLDGAEGPLLRAARWALELIPGLAEDWIHTAPAATTMAYVGS
                     VDAFGRRLPLRAAAMLLRVLRESGDRAAPDLERLVAAWSDAFAQRFRARWVPLTHQVEH
                     QSRTVLLAARQAREQAYQ"
     misc_feature    complement(20484..20499)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.76"
                     /tool="antismash"
ORIGIN
        1 cggcaccgac tcgctgcgca ccgccctgga cggggccgtg ctgtcgccga ccggctgggc
       61 ggtcgcggtg gacggcgagg ggcgcgccgt gggcgtcgtg tcgcagcagg ccatcgggga
      121 ggcgatccgc gccgcgcacg gccgggcggg ggccgaggtg aaggccgcct catgaacggt
      181 ttcttcgatc tgccgagcga cctccagtac acctacctcg gcctcgtcgg actgcatctg
      241 cgcgaggcgc tgataccggt cctggccggg ctggtcgtcg cgctgcccat cgcccagctg
      301 tgcgcccgct tccgctgggt ctacccgccc gtgctcggcc tcaccaccgt gctctactcc
      361 atcccctcgc tcgccttctt cgtcgtcctc atcgactact tcgggcagag cgagaccacg
      421 gtgatgatcc cgctcgcggt ctacagcctg gtggtgctgg tccccggcat cgtggacggc
      481 gtccgctcgg tgccccagga gacactggcc gccgccgagg cgatgggctt cggcccgctg
      541 cgccgctatc tccaggtcca actccccatc gccgcaccgg cgatcatcgc cgggctgcgg
      601 gtggcggtca tctccagcct gtccctggtc agcgtcggca tgctcatcgg caaccagggc
      661 gccctgggca acatgctcta cgacgccaac acctaccacc ggcccgccct cgccgttaac
      721 tcggtactga ccacggcggt gctgggcgtc ctggccgatg ccctgctggt cctcgtgcgc
      781 cgactgctga ccccctggat gccgaggaag ggcgccgccc ggtgaacgta ctgcacctcg
      841 tccacgcctt cttcggcgac ggcgcccact ggcacggcta cgacggcata ccggcccggc
      901 tcgccgagca cgtcacctac tcgctggagg cgctgctgat cgccgccgtg atcgggctgc
      961 ccgtcggcct ggtcaccggg cactacggcc ggggcggcaa cgcgctcgcg ctgatcgcca
     1021 ccgccgggcg ggcgctgccc agcttcgggc tgctggtgct gatggtcctg tggatcgggc
     1081 tcggcctggt gccggtgatg atcccgctgg tggtgctcgc cgtaccgccg atcctggtca
     1141 ccacctacga ggcggtggcg accgtcgacc cgtccccggt ggacgccgcc cggggcatgg
     1201 ggatgtccga ggggcgggtg ctgttccggg tcgaggtgcc ggtcgcgctg ccgctgatcc
     1261 tctccgggct gcgcacggcg gccgtgcaga tcatctccac cgccaccatc gcggcgtacg
     1321 tcggtctcgg cgggctcggc cggtacatca tcgacggcct ctaccagcgg gactacgaga
     1381 aggtcgtggg cggcgccgcc ctggtcgccg ggctcgccct ggtgaccctc ctgctgttct
     1441 gggcggccgc ccgggtcacg gtgtcccgcg gtgtgcgcag gagcacctga ccggccgtcc
     1501 gcagttcccc ctcgtccccc ttcatcgagt tcgttcccct tcatcaagaa tgcgttacaa
     1561 gagccgggcg cgccgttgac tcggcgccga gcccgtggat tggatcaggt agtgacttca
     1621 acaagccaga tcagcaggtc catacggagg aaccggggcg cggcggcggc ggtcgcgctc
     1681 gcgatggcga cggccctgct cgcgggctgt tccgccaagt ccggcggcgt ggtcgtcggc
     1741 tccaacaact tccccgagag caacctgctc gccgacatct acggcgaggc gctcaaggcc
     1801 aaggggatcg acgtcacgta caagccgaac atcggcagcc gtgagaccac ctacgggctg
     1861 ctgaagaacg gctccgtcgc cgtcctgccc gagtacaacg gggcgctgct ggcctacctc
     1921 gaccccaagg cgacgccgaa gagcgccgag gagaccacgg cggccatcaa ggccaagctc
     1981 gcctccaagc tgaccctgct ggacccctcg tcggcgcagg acaaggacag cctcgcggtc
     2041 aacgccgaga cggcgcggaa gtaccacctc accacggact ccagcgccgc cgatctgaag
     2101 gccgtcgcca aggacctggt gatcgggggc tcgccggagt tccagacccg gcagcagggc
     2161 ctggcgggcc tgaagtccgt ctacggcctc gacttcaagt ccttcaaggc cctggacgcg
     2221 ggtggcacgc tcacccagac ggcgctgaag aagaacgatg tccaggtcgc cgacatcttc
     2281 agcaccgacc ccaccatcgc caaggagaag ttcgtcgtcc tcaaggaccc ccagaacctc
     2341 ttcggcttcc agaacatcca gcccgtcgtc tccaggacgg ccctccccaa gaagggcgtc
     2401 gccgccctga acgcggtctc cgccaagctc gacaccgcga ccctgctgaa tctggacacc
     2461 caggtccagc tccagcacaa ggacccgctg gacgtggcga aggcgtggct gaagtcggcg
     2521 gggctcgact gaggcacgtg cgacgcgaag ggcggggcgc ggccgggaat tcccggccgc
     2581 gccccgccct tgtgccgtcg gtcagaggtc gaactcgtgc ggcggcagtt ccagggtgaa
     2641 gcaggcctcg cggacgacgg cctgttcggt cttgtcgaag tcgccgtcgg cgccgccgat
     2701 gacgatgccg atctggatca cggcgcgggc ctcggcgggc ttcttcttgg ccttggcgat
     2761 ctcctggagg atgctcacct tgccgaaggc gaagtcggtg gtgagcttgt tcaggttctc
     2821 gtcgaagcgg cggcgaaggt cgtccgcagg gaagttctgg agcacctcat tggtggcgat
     2881 gagctgagcg acgcgctggc gctcggaggg gtcgacggtg ccgtccgccg ctgccacgag
     2941 ggcgcacatg gccatgctcg cgtcccggaa ggcgccgctc ttcaggtcgt tcttcttcgc
     3001 caccagctgg ttctgcatct gcgacgcgga ttccttgacg cggtcccaca gggccatgct
     3061 cgctcctcat atcaacggca ggtgccccgc ggcacccacc ggcaacttct acaacaccgt
     3121 agaaactgac ggtggggccg gaaagttccg ggacgtcata ccgcgctcgt cccggcctcc
     3181 tcggcgaggg cccgtgcccg gcggcgcccg cggcggccca cccggggctc ctggtcgggc
     3241 agccagccga aggcgaggca gctgccggcg acaccgagca gcaggccgat gaagaagccg
     3301 cccagattgg acgtgaccca ggtgcccagc gacaccagca ccccgacgat ggagtagaag
     3361 agccgctgcg cggggttgaa gaggatcagc agacccagca gcgccatcag gcccggcagc
     3421 agatagccgg ccagcccctg catgccgatg tgcatcacga ccttcagcga cgccttctcg
     3481 gtcagcagga tctcgccgcc gcccagggcg agcagcagcc cgccccagaa cggccggcgg
     3541 gcccgccagg accggaagga gcgcccggca cccggccggg aacggtccgc cacggcgctc
     3601 agcaacccga gtcgctgaag cgcagcttga gacccggcag cttgaacacc cctgccgtgg
     3661 tcgcgtagtt ggtctgccgc aggtggtcga tgtgcacgct gtcggcctgc tggctgaaga
     3721 cgccgatcgg gcccttcgcg ttggcctcgg tcagcgtgct cgcgtcgttg ccgatctcga
     3781 tgtggttgaa cgacgcgtca cccgacatcg cggtggagtc ggtggtcagg tcggacgcgc
     3841 tgaccttggt ggcgccgctg cccgcggtga tcagcaggtt ggtgccgccg aggtcgacgc
     3901 tctggcacag cttggtgagg gtcgccttct tgatcgccga ggtgacgatg agctcctggc
     3961 cgccggtgtc accggcgttg gggctgccgt cggccatgtt gtccaggccg ccgaactgtt
     4021 cgaatccggt gccgtccagc tggctcgcgg tgaccgtgaa cggcatgccg gagatggcga
     4081 actgcacgcc cagcgcgccc tgcgcggtga ggaccgcgag gccggcggcg acgagggtgg
     4141 cgggcaccgc catcaccgcg gcgcgacggg cccggacgcg gccccgtctc ccggtcgcgg
     4201 gggccgcggt gctgctcggt gcttcggacg gtgaaccgct ttccgggttc tcgggggtgt
     4261 tgccggtgga cgagaggtcc ggggacgagg ccatgtctgc tcccatgggc atggatcaac
     4321 gcgggttggg cttcagtggc gcgatgtcct ggcgcggaca gcggccgccg cggacgcctc
     4381 ctcgcactcc cggcgggcgc aagggctttc tcgttacgcg gcggtagcct ttcgaggaag
     4441 ttaccgccgg ttacattttg gggtcaaggg agatgtgaaa aaagggtgtc gacggtgcgt
     4501 gcgggccgct gagggtctca acttcccctg tgtacagatg ggttgagcgg tccgatgggt
     4561 tgacgccggt ggttgacggg gttacaaatt cttcagattc cacggatccg tggcgccgga
     4621 tcccccgagc ggcagcggcc gaccgtgccc cctccgggca ccggccgcgt tcccggccct
     4681 tacgcggcac ccgctccatc ggtcaccgat cgtctcgaac tcgggccgcc gcgcacgccg
     4741 gcccctgcga acggcggccg cttcgaacgg tgatcttccc gcaccgcgcg cgagtacggc
     4801 acggacagct ccccatgggt ccgtaccggc attccccttg ttcgtccggc ccagccgatt
     4861 ccccccgggc accggccggt gtccggcccg ccgccgtcgc cggtccaccg cgtaaggaga
     4921 aggcgtgacg gacccgcgcc ggcggcgaca tccgcaccac ccggcaccgc cgcgcaccgc
     4981 ccccaccccc cacgtccgtg tttccccacc tcatgagaga ggcacccgca tgcgtacgcg
     5041 taccctcatc gctctcgccg gcaccgccac cgccaccgcg ctcgccctcg tgtcggccgg
     5101 tccggcctcc gcggccggct cggtcctcac caagggcagc gccggcggca ccgccgtcgc
     5161 ggtcggcgac accctcaccg cgccgctggc gagcggcacc tcggccacct tctactccag
     5221 ctcgaccggc accagcggcg tgaagtgcgg cacctcccag ttcaccgcca aggtgaccgc
     5281 caacccgacc gcgccgggca ccgccaccga gtccctcacc ggtcagacct tcagcggctg
     5341 caccagcaat gtcaccggtg tcctcggtgt cggcagcgtg accatcgaca acctgcccta
     5401 cacggcggcg gcctcctcca gcggcaccct caccgtctcg cccccgagcg gctccgtcat
     5461 ccagtccacg gtcaagctga acaccctgct gggcagcgtc acctgcgtct accagggccc
     5521 gagcctggcc gggaagacgg ccaacgccga caacagcatc accttcacca accagcagtt
     5581 caccaagacc tccgggtcct cgctctgctt ctccaccgcg tacttcagcg ccaagtacgc
     5641 cccggtgacg gacgctgggt cctcggtcta cgtcaactga cgtcccccgg gcggtcgttt
     5701 cgggccgttc tgaacgcagc gcccaggcgg cgccgacgcg gtgctctccg gcatcgcggc
     5761 ggcgccgccc tgctgtgcgc ggtcatgccg gcaggggtcg tactgcctta cagcgcaagg
     5821 cagttggcct ttttcggccc tccggtgaga cgccattgag gagccggtcg tccgcctcgt
     5881 atcgtggcga tcatgggggc tcccgttgtc attcggtgag ttatcgtatg caaggggtta
     5941 aaaacaaacc gcatgtcccg ttcgttcgtc tcgcgaggag gggtcccagc atggcgaggc
     6001 agttacgcgc cgaacagacc cgggccacga tcatcacggc cgccgccgat ctgttcgacc
     6061 aacacggcta cgaatccacc agtctgagcg acatcgtcgc acacgcgaag gtcaccaaag
     6121 gtgccctcta cttccacttc gccgccaagg aggacctggc gcacgcgatc ctggagctgg
     6181 agaaccgcgc ggcccgccgt ctggtggccg atctcgacgg ccgcggctac tcctccctgg
     6241 agggcctgat gcgcaccacc ttcgggatcg cccggctcgc cgtggacgac ccggtgccgc
     6301 gcgccggact gcgcctcgcc accgccgacg tgaaggtacg gccgccactg cgccacccct
     6361 acaccgagtg gctggagttc gccggccgca agttcaccgg ggccgtgcgc gaggccgatg
     6421 tgcacgggga cctggacgtc tcggccgccg cccactcgct cgtctgcttc ttcttcggca
     6481 cccgcgtcgc cggccgcttc gaacccgtgg gacgcctgcc gcgccgggtc gccgagatgt
     6541 ggcacctgat gatccgcggc ctggtcccgg tgcaccgccg cccccgctac gtcaccctcg
     6601 ccacgcagct ggagcgggag atcagaaccg cgtgagacgc gcggtacggt gacggacatg
     6661 cccgaaaccc cgttcgcatc cgtgattctc ggcaacgaac ccggctcgtt cccgcacggc
     6721 gtgctggccg agcggcaccc ggcgatcgtc cgccaggtgc gggacgccct cccgtacggc
     6781 cccgggcagc accgggcgct ggacgaactg ctgaagagct gcgccgaggg gaccgtggaa
     6841 cccctgcccg ccgacgcccc ggaccgggcg gcgtggcacg cgtggggcct ggccgagtac
     6901 gccgggcggt cctggttcga cgtgccgtgg ctgtggtccg agagctactt ctaccgccgg
     6961 ctcctcgaag ccgtcggcta cttcgcgccc ggcccctggc ggggcatcga ccccttccgg
     7021 cccgtcaagc gcgcggaact ggccgcgccc gagaccgacc gggaactcgc cgccctcgac
     7081 gacctgcggg aactgcccga accggagcgg gaccgcgccc tgctgcacgg ctcgctctgg
     7141 ggcaaccgcg ccgacctggg cttccggctg tccgccgagg gcgccgaggc ccgggaaccg
     7201 gcgcccgcgc tggtcgccga cgacagcgag cggctgtgga cgctgctgcc gcccggcgga
     7261 gccgccgacc tcgtcctggt cgcggacaac gcggggcgcg aactcgtccc cgacctgctg
     7321 ctgatcgccc atctcctcgc cgggggccgg atcgcgcggg cggtgctcca ggtgaagccg
     7381 tacccgtact acgtctcgga cgcgatcatg gccgatgtgc tcgacgccct ggaacggctg
     7441 cgtacggcgc cgggcgcggc cggggagcac gggcggctgc tccgctccgc catggccgac
     7501 gggcggctca ccgtgcgcgc ccaccccttc tgctgcgccc cgctgccgta cgagcggatg
     7561 ccggacgacc tgcgtgccga gttcgccgcc gccaccctca ccgtcttcaa gggcgacctc
     7621 aactaccgcc gtctggtggg cgaccggcgc cgcccgccga ccgcgtcgtt cgccgcggcg
     7681 accgcgtact tcccgggtcc ggtggccgcg ctgcgcaccc tgaagtccga ggtggtcacc
     7741 gggctggccg ccgccaccga ggagcggctg gtggcggcgg aaggccagcg ctggcgcacg
     7801 gacggcaccc acgcgctgat ccaggtcaac ccaggtgcac cggcagcgac ttgagcccgt
     7861 tgatgaagtt cgacaccagc cgctcggccg gccccgcggg gcgcagcacc ggcagggcgc
     7921 gcagcgcctc cgcgtagagc agccgcagtt gcaggcgggc gaagtgggcg cccaggcaga
     7981 cgtgcgggcc gtccccgaag gagacgtgcg ggttggggga gcgggcgagg tccagccggc
     8041 cgggctcggc gaagacccgc tcgtcgcggt tggcggaggc gtggaagacc acgaccttgt
     8101 cgcccgccgc gatgcgccgg cccgccagct cggtgtcccg cgcggcggtg cgccggaagg
     8161 tcagcacggg cgggtgccag cgcagcaact cctccacagc cggggcgagt tcggccttgc
     8221 cggtgcgcag cagctcgtac ggctccgggt gctcggccag ggccagcagg ccgcccgggg
     8281 ccgcgccgcg gacggtgtcg ttgcccgcga ccgtgagcag gaagaagaac atctccagct
     8341 cgggcccggt gagttcgggg tcggcggcga gggtcgtcat gatgtcgtcg gcggggtgcc
     8401 ggcgcttgtg cgcggccagt tcgcgcgcgt aggcgaacat gtcccgcagc atcgccgggg
     8461 agcgcgggtt cagcggcttg cccgagccgt cgaggacccg gggagcggcc tcgtccgggt
     8521 cctggtagcc gatcacccgc cgcgtccagc gcagcagcag ccggcggtcg ccctccggga
     8581 cgcccagcag atcggtgagg ttgagcaggg cgtactcgtc ggtgacggcc gccaccaggt
     8641 cgaccgtgcc gtccccgagc gcggcccgct cccgtgccgc cgcgagcagc gtccgcgccc
     8701 gctccccggc gagggccgcg aaccgctcga tccgccccgg ggtgaacgcc cggctcacca
     8761 gccgccgcaa ccgcccgtgg tggggcgggt cctggttgag catcatgcgc cggatgaacg
     8821 gcagatcctc cgggtcgggg tcccggatct gggtcgcgcc gaggcgcgag gagtacgcgg
     8881 ccgagtcctt caggacccgc acgacgtccg cgtgccgggt caccgcccag aacccgggac
     8941 ccgcgggcca gcccagcacc tcgggctcct cctgccaggc caccggatgc tcgtcgcgca
     9001 ggacgcggta ggcgtcgtac ggcaccccgg aggcgtaccg gcgcgggtcg aagacgtccg
     9061 gcacgggacc ggcggttcct gtgctcacgc ctcgtcgctc ccgtccgcgc gcaggaagtc
     9121 ctccaccacc cggatcagct ccagcggtgt ctcgtccatc gcgtagtgcc cggccccggg
     9181 cagggcgacg agatggccgt gccggtacca ggacagccag gtcctgcgca tcagctcggg
     9241 cgtcagggcc gggtccagtt cgcccgccac ggccagcgcg ggcacctcgc tgccggtcac
     9301 ctcggcgtgg aagtcctcgc ccgcccacga gtccagccag gcccggaacg ccttcgcgtc
     9361 gctgcgctgg aacgaggtcc agaccatccg gtccagccag gcggccgggc ggcgcccgcc
     9421 ggtggtgaag tcgatgatcg cgcgccggtt gcccgccttg tgcgccgcgt ccgtgaacag
     9481 cgcgccctgc tcgcccgaga gcggcatccc cgcggccggc accggggaca cgccgacgac
     9541 ccggcgcagc cgcccgggcg cgagcgcgag cagccgctgg gctaccgcgc cgcccatgga
     9601 gtgcccgatc accgagaacc tggcccagcc cagccggtcg gccagcgcca ccaggtccac
     9661 ggccgcctga gccgtcgtat acggccccgg ggcgtccgcg gcctccccgt agccgcgcag
     9721 atcgaccggc acatacgtga agctggtgcg gtccaggtcc ggcaggacgg ccgcgtaggc
     9781 ggagcggtcg gcgaaccagc cgtgcacggc gaacacccgg tgggcgccgt cgccgtgcac
     9841 ctcatggggc agcacgaagg agttcatgcg cctaccgtgg cccgggcacc tgagcacggc
     9901 aagggcgcgg acggggccca cctcggggcc ggttcacgcg atggtgtgat catgtcccgc
     9961 gcgtgggatg ggtgttcggg gtgccgggta gggcccggcc atgacgcagc cgttcgaact
    10021 cccgcacttc tacatgccgt tccccgcgcg gctcaatccg cacctcgacg aggcacgcgc
    10081 ccattccacc gcgtgggccc gcgagatggg catgctggag ggctccggga tctgggacca
    10141 ggccgacctg gacgcgcacg actacgggct gctgtgcgcc tacacccacc ccgactgcga
    10201 cggcgccgcc ctctcgctga tcaccgactg gtacgtgtgg gtgttcttct tcgacgacca
    10261 cttcctggac atgttcaagc ggacccagga ccgcgccgcc ggcaaggccc acctcgaccg
    10321 gctgccgctg ttcatgccga tcgaccccca cgcccccgtg cccgagccgg agaaccccgt
    10381 cgaggcgggt ctgaaggacc tgtgggcgcg tacggtgccc gcgatgtcgg tggactggcg
    10441 ccgccgcttc tcggtgtcca ccgagcatct gctcaacgag tcgatgtggg agctgtccaa
    10501 catcaacgag gggcggatcg ccaaccccgt cgagtacatc gagatgcgcc gcaaggtggg
    10561 cggggcgccc tggtccgccg ggctcgtgga gtacgcgacc gccgaggtgc ccgccgccgt
    10621 cgcggagacc aggccgctgc gggtgctcat ggagaccttc gccgacgccg tccacctgcg
    10681 caacgacctg ttctcctacc agcgcgaggt cgaggacgag ggcgagaaca gcaacggcgt
    10741 gctcgtcctg gagaccttct tcggctgcac cacccagcag gccgccgaca ccgtcaacga
    10801 catcctcacc tcacgccttc accagttcga gcacaccgcg ctcaccgagg tgcccgcgat
    10861 cgccctggag cacggcctca ccccggccga gacgggcgcg atcgccgcct acgccaaggg
    10921 actccaggac tggcagagcg gcggccacga atggcatctg cgctccagcc gctacatgaa
    10981 caagggcgcg cgcagcgact cgccctggcg gctgccgagc ggccccggca cctccgccgc
    11041 gcacatcggc gccctgctcg cctccgccgc gcacgagcgg ctgcgcgcct actcgcatgt
    11101 gccccaccag aaggtcgggc cctcgatcct gcccgagttc cacatgccgt tcgccctgga
    11161 gctcagcccg cacctggacg ccacccgccg caacctgcgc gcctggtgcg accggatggg
    11221 catcctccag gagggcgtct gggacgagga caagctgcgc gcctacgacc tcgccctgtg
    11281 ctccgccgga ctcgacccgg acgccacccc ggaggccctc gacctcagcg cccagtggct
    11341 cgccttcggc acctacggcg acgactacta ccccctggtg tacggccatc gccgggacct
    11401 ggccgccgcc cgcctcacca ccgcccggct gtcggcctgc atgcccgtcg acggcgagcc
    11461 cccgctggtg cccggcaacg ccatggaacg ctccctgggc gacctgtggg cccgcaccac
    11521 cgccccgatg agcaccgggc agcggcgcac cctcaagcag gccgtggaca ccatgaccga
    11581 gagctgggtg tgggagctgt ccaaccagct ccagaaccgc gtccccgacc cggtcgacta
    11641 cctggagatg cgccgcgcca ccttcggctc cgacctcacc ctgagcctgt gccggatggg
    11701 ccggggcccc gcggtcccgc cggaggtcta ccgcagcggc ccggtgcgct ccctggagaa
    11761 cgccgccatc gactacgcct gcctgctcaa cgacatcttc tcgtaccaga aggagatcga
    11821 gtacgagggc gagatccaca acgccgtcct ggtggtgcag aacttcttcg gcgtcgacta
    11881 cccgaccgcg ctcggcgtcg tccacgacct gaccacccag cgcatgcgcc agttcgaaca
    11941 cgtggtcgcc cacgaactgc ccgtgctgta cgacgacttc gggctctccc cgcaggcccg
    12001 cacggcgatg gacggttacg tcgacgacct gcggaactgg ctcgcgggga tcctcaactg
    12061 gcaccgcagc gtggaccgtt acaaggacgc ctggctgtcc cggcgcgccc acggcttcct
    12121 gcccgaccgc ccgcccgtgc gcccgctcct cactccgggc tgatccaccg tttcggtggg
    12181 gagaagaagg aggcgccggg cgaactcagg ctgtatgcgg cgtcaccggc ggcggcaacg
    12241 acggctgggc ggacaacgcg gtcggcgccg gcggagccca gctgtcggag tacccgaacg
    12301 accaccagac gacgcagtgg cggtaccacg accacgagca gtggagcttc ctcgacctcg
    12361 cgcccatcgt gcaccccatg cacatccacc tggccgactt ccagctgctg ggccgggacg
    12421 cccacgacgt ctccggcttc gacccggcgg ccggcggcac ccgcgccccg atccgccacg
    12481 acgcgggcac cgcgatcccg ctcgcgccca acgagcaggg gtacaaggac gtcttcaggg
    12541 tgcccggcgg ccagccgctg cgggtcatgg gccttcgacg gggcgcacga cggcggccac
    12601 ggagggcaca tgggctgagc cgaccctgag tggggggccg gggccggtgc gcggggtgtc
    12661 cgtagtgact acccgccgcg ggcgtcccgt cagtctcact cgttcgtgtc tcgtcgccgg
    12721 ccggtgcgcc gggtagatga ccggccggag gcgagcgaac catggaacac actgcgttgc
    12781 ggcccaggcc gctgcccggc cggggccccc gcacgggcgg cggccctcgc acgggcggcg
    12841 gccccgccca ccatccgcac gccgcgtccc ggcgcgtacg gcggctgcgg accctgctgc
    12901 tcggcgtctg cgcgggcacc ctgctggtgc tgtccggcgt gggcatcggc gcggtcggcg
    12961 ccacggtgct cggcgcgggg cagagcgccg aaccgcaccc cccggccgcg gccccgcccg
    13021 cgcgggacag cggacccaag gccaccctgg gcgtggaggc cgtcgactac ggcagcccgg
    13081 gcgcgctggt ggtgggtgtg cacacgcccg gccccggctc ccgggcgggc ctggcccgcg
    13141 gcgacgtcct gctccagttc ggcggcgccc gcgtcgacac cgccgccgac ctggccgggg
    13201 ccgtcgcccg cgcccgcccc ggcagcgaga tcctgctcac cgtgcggcac agcggcggcg
    13261 gattccagca gctgacggtg gtgccgggcg tggtgacctg agcgcggcgg ggtccggggg
    13321 ccgccggcca tgacggccgg gtgccgaggg tcctgccgac ctctgcgacc cgccgcgcgc
    13381 gcggccgcgc cgtgcccggc ggacgcggga tcgtccgatc gggtcgcgtg gcccggtccg
    13441 ggcgggcagg atgctgcccg gggcgccttc cgcgcgcccc ggcacctgcc cgaccagcca
    13501 gaaccgcccg gaggcccgga tgaccggtag gacgaccacg cccttcagcg cagccgacca
    13561 caaggcccgc atggagcgtg ccgcgcgcgc cgcggccgac gccggactcg ccgggctgct
    13621 cgtggcgccg ggcccggaca tggtgtggct gaccggctac acccccaccg ccgtcaccga
    13681 gcggctcacc ctgctggtcc tcgcccccgg ccgggacccc gtcctggtcg tccccaccct
    13741 ggaggccccg gacgccgagc actccgtcgc gggcgaggcg ctcaccctgc gcgactggac
    13801 cgacggcaag gacccctacg ccgtcaccgc cgagctgctc gacggccgcg gccgctacgg
    13861 catcagcgac aacacctggg gcatgcacgt cctcggcctc cagcgcaccc tgcccgacag
    13921 ctcgtacgcc gccctcaccg actccctgcc catgctgcgc gcggtcaagg acgccgccga
    13981 ggtggaactg ctcgcggccg ccggagccgc cgccgacgcc gcgttcgagg agatccgcaa
    14041 ggtgaccttc gccgggcgcc gcgagtccga cctcggccgc gacctcgccg cgctgctgcg
    14101 ccgcttcggc cactcccagg tcgacttcac catcgtcggc tccggaccca acggcgccaa
    14161 cccgcaccac gaggtcggcg accgcgtcat ccggcgcggc gacatggtcg tcctcgactt
    14221 cggcggcctg aaggacggct acggctccga caccacgcgc accgtgcacg tcggcgagcc
    14281 caccgaggag gagcgccggg tccacgacat cgtgcgcgag gcccaggagg ccggctacca
    14341 ggcggtgcgg ccgggcgtgg cctgccagga cgtcgaccgg gccgcccgcg cggtgatcac
    14401 cgacgccggg tacggcgagt acttcatcca ccgcaccggg cacggcatcg gcgtcaccac
    14461 gcacgagccg ccgtacatga tcgagggcga ggagctgccg ctggtgcccg ggatgtgctt
    14521 ctcggtggag cccggcatct atctgcccgg ccggttcggg gtgcgcatcg aggacatcgt
    14581 gacggtgacc gaggacggcg gccgccgcct caacaacacc ggccgcgaga tggtgaccgt
    14641 ggactgacgg cccgcccgag cccgggtccg aggcggcccc gggcgaccac cccgacgaca
    14701 cccggaacgg caacgcgcga tccatgaccc aggcaccgac ccccaccgcg gacaccgtcc
    14761 gccagctggt ccgttcgctg ctcaaggaag gcccggacgg cgacggaccc gacgtccggc
    14821 ctgtccggga ggggcacgcg tacacctggt gggtcggcac ccgccaggtg ctgcggctcg
    14881 cccccgaccg ggaggcgtcc gcccgccgcc gccgggaact gcggctgcgc gccctggtcc
    14941 ggccgcacgt cccggtcgcg gtgccggtca gcgtcgcgca cgccgactgg gcgcccggcc
    15001 tcgcctgcac cctggacacc gtggtgcccg gcggcaccgc cgaggagcac gaggtctcgg
    15061 cggccggcga ggccgatctc gccggactgc tcaccgggct gcgcgcggtg ccggtacggc
    15121 aggccgacgc gctcggcgtg ccgcgcgccg ccccgcgctc cctggaggcg ctgcgccgga
    15181 tggccgtgca cgcggccgaa cggctcgccg ccgccgacga gttcgacgcc gcgccgatgt
    15241 accagctcac cccggccggg gccgcccagc tggccgcgca gcccggtgtc gccgtgctca
    15301 cccaccacgg gctgaccggc gaacgcgtgg tggtcagcgc cgacgggcgg gtgcgcggcg
    15361 tcctcgactg gaccgaggcg gcgctcggcg atcccgccga ggacatcgcg gggctcgccg
    15421 tcgccgtcgg ctccccggcc gccgtccgcg ccgccaccct cgccgggtac ggcgcccgcc
    15481 cctgcctgcg cggcctctgg ctcgcccgct gcgacacggt gctgcgcctg atggaccgcc
    15541 tcgacgaccg cgctcccggc gacccgacgc tgctgcgcag ccggctgcac cgggcgtggg
    15601 agccgatcct gctggagcgg gtgacggact tcaagacggc gggggaggag ccgtaacggg
    15661 cgttcccccc aggccacctc ccccccgcct caggaatcct cccctcaggg ctgcttcttt
    15721 ccgtctcagg gctggctgag caccacgcac gactccccgg gcagctggag catgccgtcc
    15781 gcgcccggcg gttcgaccgg ctcccacgcg gcgaggacca gggccgggcg ggagcccagc
    15841 gggatggcgg ccggttcctc gcccaggttc accgcgaccc gtacatcgcc ccgccggaag
    15901 gccagccagc gggcctgccc gtcgtaggcg accttcgtgt cggcgaggtc cgggtcggtc
    15961 aggtccggct ggtcgcggcg cagcgagatc agccgccggt accagtccag catccgtgcg
    16021 tgcgccaccc gttcgggttc cgaccagtcg aggcaggagc gctcccgggt cgccgggtcc
    16081 cccgggtccg gtacgtcctc ctcggcccag ccgtgcgccg cgaactcccg gcgccgcccg
    16141 cgccgtaccg cctccgcgag tccggggtcc gtatggtcgg cgaagtactg ccagggcgtg
    16201 cccgcggccc actcctcgcc catgaacagc atcggggtga acggcgcggt cagcaccagc
    16261 gtcgccgcgc aggccagcag gccgggggag agccgggcgg agagccggtc gccctgggcg
    16321 cggttgccga tctggtcgtg ggtctgggag tagccgagca gccggtgccc ggccacccgc
    16381 gcccggtcca gcggtcgccc gtggtgccgg ccccggaaac cggagtacgt gccgtcgtgg
    16441 aagtagcccc cggtgagcgt cctggccagc gcggcgaagg gatcgcgcgc gaagtccgcg
    16501 tagtagccct gggactcgcc ggtcagcgcg gtgtgcaggg cgtggtggaa gtcgtcgttc
    16561 cactgcgcgt gcagcccgag cccgctctcc gcgcgcggcg tgatgaagcg ggggttgttg
    16621 aggtcggtct cggcgatcag gaacagcggc cggtccacct ccgccgcgag gtggtcgacg
    16681 gcggccgaca gctcctccag gaagtggacg gcccgggtgt cgtacagcgc gtgcaccgcg
    16741 tccaggcgca gcccgtcgag ccggaagtcc cgcagccacg ccagcgcgct gccgacgagg
    16801 aacgcgcgca cctcgtccga accgggcgcg tccaggttca tcgccgcgcc ccacggcgtg
    16861 gtgtgggtgt cggtgaagta cggcccgaag gacggcagat gattgccgga gggccccaag
    16921 tggttgtgca cgacgtccag gacgacaccg agtcccagct cgtgcgcccg gtccacgaac
    16981 cgcttcagcg cctcggggcc gccgtacggc tcgtgcaccg cccacggcga caccccgtcg
    17041 tacccccagc cgtgccgccc ggggaacgga cacagcggca tcaactccac gtggctgatg
    17101 cccagctcca ccagatgacc gagccggtcc gccgccgcgt ccagggtgcc ctcgggggtg
    17161 tacgtgccca catgcagctc gtagagcacc gcgcccggca actcccgccc cggccacggt
    17221 acccgccacc ggtaccgctc ctggtccacg accgcgctga gcccgtccgg cccgtccggc
    17281 tggcggcgcg agcgcgggtc gggcagcacc ggaccgtcgt ccagcgcgaa tccgtaccgg
    17341 gcgccgtcac ccgccgtcgc ctcccccttc caccagccct cgcgctccgg atcgcgcgcc
    17401 aacgcccgcg cggcgccctc gcaccggagc gtcacccggt ctgcctgcgg tgcccacacc
    17461 tcgaactgca cggacggttc cccttcgtct gttcaccgtg atgtcccgcg ctcccatcgt
    17521 gcccgccccc gccgtcgatc tccccttcaa tcggcgcctt tccctccagg tgtcgtgcga
    17581 tgttccccgg cgggccgcgc ggaagtaccg gaccgtgggc gccgattacc cgttttctgg
    17641 acactcgcgg cccactgacc gacaatcaca ggcgtgacgt cgtccttcga gttccccacc
    17701 gccccggccc cggcgtccgc gcggctgtcc gacacggagc gggaagcggc gctggaggtg
    17761 ctgcgggacg gcgcggccaa gggccggctg tcgcacgaga cgttcgtgcg ccgcatggaa
    17821 ctggcgctcg ccgcgcgcca cgccgacgaa ctcgccgtcc tcgtcgccga cctgccccgc
    17881 gagaaccgcc tgtcccgcgc ggtcttcggc accgtggagg ccgtctccgg cttcacggta
    17941 cgactgcgcc gcgcctggca ggccgagcgg ctgcccaagc tgctgctgcc gggaccggcc
    18001 cacacccgcc cgctgcggat aggccgcgat ccgggcaacg ggctgcggct gacccatgag
    18061 acggtctccc gggtgcacgc cgaactcagc caccagggcg ggctgtggat cctgcgggac
    18121 ctcggctcca ccaacgggac caccgtcaac ggccgccggg tgatcggcgc ggtcgcggtc
    18181 cgcgagggcg accaggtggc gttcgggcgg gtggcgtacc ggctctcgct gagctgagct
    18241 gagctgagcc gagccgagcc gaggtgggct gagccgagcg tgcggccccg gccccggcgc
    18301 cgcggtcgcg cgaacgggtg acccgcactg cggaacggcg gacgtcctgc cgatgcaacg
    18361 ggcatgacgt acttcaccag agcgaccacg gccgccggcg tgctgctggc caccgccggt
    18421 ctcctcgccg cgggccccgc ccaggcggta ccccatccgc acggcaaccg gctgcacctc
    18481 acgatcaccc gctcgggcct gcgggccgac agcggccgca gcgccctgct gcgctgcctg
    18541 ccgccccacg gccatccgta cgcggccgag gcctgcgccg aactggccgt cgcccgcggc
    18601 gacatcgacc gcatcccggc ccgcaaggtg ttctgcccgc ggatctactc cccggtcacc
    18661 gccacggcgc gcggccgctg gaacggccgg ctggtcgact tccggcggac ctacaccaat
    18721 tcctgtgaac tgcgggcgcg gacggggtcg gtcttcgacc tcggcgactg accggcggcc
    18781 cccaggcgcc gcccgtccgg ccggtgtccc tactgatacg cctgctcccg ggcctgccgg
    18841 gccgccaaca gcaccgtgcg cgactggtgc tccacctggt gggtcagcgg cacccagcgg
    18901 gcccggaagc gctgggcgaa ggcgtcggac caggcggcca cgagccgttc gaggtccggc
    18961 gccgcccggt cgccgctctc ccgcagcacc cgcagcagca tcgcggccgc ccgcagcggc
    19021 agccgccgcc cgaacgcgtc cacgctgccg acgtacgcca tcgtggtggc ggccggcgcg
    19081 gtgtggatcc agtcctcggc cagacccggg atcagctcca gcgcccagcg cgcggcccgc
    19141 agcagcggcc cctcggcgcc gtcgagccgg ggcagcgcct ccgcgagcac ccgctccacc
    19201 tccagcgagt cccgcagcag ccgccgggcc aggcgccgta tcgccgccgc cggtgccggg
    19261 tgcggcgccg ggtcgtccac caggtcgctg gcccacatcg gcacctccac cacggccgtc
    19321 agacccccgt agcggtgcgc gtggtaccag gtgctgtgcc gggcgtcgtc cggcatgctc
    19381 gggtaggcca cgcccgtctc cgggcccggc atcacatgca ccccgggccc ggacgccggc
    19441 cagcccgcgg cgtccgaggc gccggtctcc accgggatgt gcagctgggc cgccgacttg
    19501 gcgaacggct ccgcgagacc cggcacgtcc cgggtcaact gcacccagct gccgcccaga
    19561 tcggtgccgt gcagggtcac ctggaggtag gggcgcagct cgtcgatcac cccggtcagc
    19621 gcctgggtct cgggcggcag ccggtccggg ggcagcacgg acggcgacca ctccggctgc
    19681 tcggcgcccg tgggccggta gaagccgagg tggtagtcga gcaggctgcg cggggcgggg
    19741 gtgacatgga gggcggcgcc gtccgggtcc gcgcacagca ggaagtgcca ggagatgccg
    19801 gagcgcaact caggttcggc caggactcgt tgggccagta cccgcaaagt ggagccgccg
    19861 gtgggctcgt tggcgtgggc gcccgccacc accagcaccg accgccgtgc gtgccccacc
    19921 gacagcaggt gcaggggacg ccccgcgcgc gagcggccca cctgccgcag cgcgcacagc
    19981 ccgggttccg aggcggccaa cgcccgtgcg gaggccacca gttcgggaac gctgggatag
    20041 cgcagctccg gcaggagact cacccccgat tcgtccgccc tgcttcgccc tcccagtccc
    20101 gcacggtgcg cggtggctgt caagcgtgtg gccggatgcc cgggcggcat gtgccgaccg
    20161 gagccggggc caccgcacgc acggcgctca ccgctggtgc ggcccccgcc ccgcgagcgc
    20221 cggaaacacc tcgcccaccg cctccgggag ccgcccgtgc gccatcccct tcgccgacgc
    20281 gggcaacggc atgccacgca cggcaggctc atgccccgcc cccgcccccg cccgcgcccc
    20341 tgcgcctcgg cctcggcgag aggtccgcga gtcacggggg gcgggggccc cgccgtgatc
    20401 gccccggagc cgccgcccgc acggcgctgt tgtgctcccg gcggcccgcc gacccacccg
    20461 tgagccgtgg tccggcggtc cgagtggctg tttctcattc ctccgtgagg cgttccagca
    20521 gcgcgaccgg ctggggtccg aacaggtccg ccaggcgtac ccggccggtg aactgccggg
    20581 ccgggtccag gacatcgccc catcggccgg ggggcagcgg gaggctcgtg tcctgccagc
    20641 cgcccgatcc ggtgagccgc agcgagagcc gggtcaccgc tgtgatcacc tccccggagc
    20701 gggcgaaggc cgtgcagtgc tccgccgccg ggccctcggc ggccagcgga tcgtaggtcg
    20761 ctgacgcccc gaaggcatcg ggcctgcggg cgcgcagccg cagcgccgcc cgcgtcaacg
    20821 cggccttctc gcccgggttc tcgggcggca gggcggccgg gcggcggttg tccgggtcca
    20881 ccagcgcgcg gaactcgccc tcggtgccct ggtagacgtc cgggacgccc ggcatcgtca
    20941 ggtgcaccag ggccgtgccg aggacattgg cgcggatgtg cggctccagc gccttgcgga
    21001 aggcggtcac gcgttcgccg ggcggcccgc agggaccggc cgcggcgaag gcggtcaccg
    21061 cctcctcgta cggcgtctcc cgctcggtcc agctggtgta catgccggcc tcgcgcacat
    21121 gcttcagcag gtactgccgc acccgctcct cgtcggccgg gccgagcccg aacaccgtct
    21181 gccaggccgc ccaggccagc tgcccgtccg gggtgccctc ctcggcccgg gtcagctcgg
    21241 tcaccagctc cgcccagcgg ccggggcatt cggtgaggac ggcaagggcc gcgcggacgt
    21301 cggcgctgcg cttggtgtcg tgcgtggtga cggccgtacc ggtgagcggc cgctcgtcct
    21361 ggacgcgggc gcagtacatg tggaactcgc gcggggagat ccccggccgc cccgggtcgc
    21421 cgcccacctc ggtcgccgac agcagcggca catagcggta gtacgccgtg tcctccaccg
    21481 acttggcccg cagcgcggag gccgtctgcg cgaaccgggt gcgcagttcg agccggtcgg
    21541 cgtggtccgg cgcggccggg tccccgggcg cctcgacgag cagctgccgt acgacgtcga
    21601 cggccgccgc ctcctcgggg accacgaagg cgagccgggc ctcctcggcg gcctcctcgg
    21661 tgacgacggc ggccgcgtcc ccggaggcgt agggccggta gacccgcatc cggaccagga
    21721 gttcctccag ggccgtgcgc agcgcccagg gcgcccggtc gcgcagcgcg aggtcggggg
    21781 agtgggcgca cagccgtgcc gcgacccggg tgagccgctc ggtctcggtg gccagctcgt
    21841 gcgtgagcac cttgtaggcg gcccggcgga ccgtggcgtc ccagacaccg ccccggtccg
    21901 actgcggggc cgcgaaccgc cggtactccg tgaggagctc caccgccccg tccgggtccg
    21961 tgaacaggcc gtcgacccgg cgcagcgcgt cgtagccggt ggtgcccgcg accggccagg
    22021 agggcggcag ccgctcgtcg tcggcgagga tcttctcgac caccgtccag cggccgccgc
    22081 tcgcctcgtg cagccgggcc agataggcgt cggggtcggc gagcccgtcg gggtggtcga
    22141 cgcgcagccc gtcggccacg ccc
//
