LOCUS       NZ_CP047144            21086 bp    DNA     linear   CON 30-JAN-2024
DEFINITION  Streptomyces sp. HF10 chromosome, complete genome.
ACCESSION   NZ_CP047144
VERSION     NZ_CP047144.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. HF10
  ORGANISM  Streptomyces sp. HF10
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7814787)
  AUTHORS   Li,J., Ni,J. and Li,Y.
  TITLE     Multiple polyene macrolides produced by antifungal Streptomyces from
            gut of Macrotermes barneyi facilitates the termite-fungus mutualism
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7814787)
  AUTHORS   Li,J., Ni,J. and Li,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-DEC-2019) State Key Laboratory of Microbial
            Technology, Shandong Unversity, 72 Binhai Road, Qingdao, Shandong
            266237, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 10-NOV-2018
            Assembly Method                   :: SPAdes v. NOV-2018
            Assembly Name                     :: SDU_Sthf_5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/30/2024 05:29:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,091
            CDSs (total)                      :: 6,988
            Genes (coding)                    :: 6,640
            CDSs (with protein)               :: 6,640
            Genes (RNA)                       :: 103
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 79
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 356
            CDSs (without protein)            :: 348
            Pseudo Genes (ambiguous residues) :: 0 of 356
            Pseudo Genes (frameshifted)       :: 235 of 356
            Pseudo Genes (incomplete)         :: 154 of 356
            Pseudo Genes (internal stop)      :: 18 of 356
            Pseudo Genes (multiple problems)  :: 53 of 356
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:39:54
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5187935
            Orig. end                         :: 5209021
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP047144.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Jinfeng Ni.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21086
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="15"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21086
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21086
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11086](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11086
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            664..1257
                     /locus_tag="GR129_RS23280"
                     /old_locus_tag="GR129_23280"
     CDS             664..1257
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016437896.1"
                     /locus_tag="GR129_RS23280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_23280"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_145487201.1"
                     /transl_table=11
                     /translation="MAAARESLLDAAVAALARRPWPTVRMVEVAASAGVSRQTLYNEFG
                     GKAGLARALVRRAADGYLAGVERALAGGGGDWERLTAVAEWTAGAAQEDALVRALLTGC
                     WSERLPAPHRGPSPVPAPRRPERPLPSPPDLVRLVRDRAVTALSGPGTGPAATAELARS
                     CELVLRLALSCVTAPPAEGGLPALLRSLAPRTTL"
     gene            complement(1400..1723)
                     /locus_tag="GR129_RS23285"
                     /old_locus_tag="GR129_23285"
     CDS             complement(1400..1723)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018845570.1"
                     /locus_tag="GR129_RS23285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_23285"
                     /product="multidrug efflux SMR transporter"
                     /protein_id="WP_159704812.1"
                     /transl_table=11
                     /translation="MAWLLVIVAGMLETGFAVCLKLSHGFTRLWPTIAFASFALGSFGL
                     LTLSLRKLDVGPAYAVWTGIGATGTAIYGMIFLGDLVSTLKIISISFVIVGIIGLQLSG
                     SSH"
     misc_feature    complement(1738..1751)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     gene            complement(1808..2818)
                     /gene="rsgA"
                     /locus_tag="GR129_RS23290"
                     /old_locus_tag="GR129_23290"
     CDS             complement(1808..2818)
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rsgA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006142295.1"
                     /locus_tag="GR129_RS23290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_23290"
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="WP_159704815.1"
                     /transl_table=11
                     /translation="MRRYGKNTDEDDIRSRPNRKGNRPRTHIRPKHEDAAEGLVLTVDR
                     GRLTCLVEDRVVMAMKARELGRKAAVVGDRVMLVGDLSGKKDTLARIVRIQERTSVLRR
                     TADDDDPYERVVVANADQLAIVTALADPEPRPRLIDRCLVAAYDGGLEPLLVLTKSDLA
                     APDELLELYGHLDIPYVVTSREELENGDAADRVREFLDGRITAFVGHSGVGKTTLVNAL
                     VPEERRRTTGHVNAVTGRGRHTTTSALALPLAGDDGWVVDTPGVRSFGLAHIDPSRVIH
                     AFPDLEPGTADCPRACGHDEPDCALDAWVEAGHADPARLYSLRRLLATRERTEGD"
     gene            complement(2828..4168)
                     /gene="aroA"
                     /locus_tag="GR129_RS23295"
                     /old_locus_tag="GR129_23295"
     CDS             complement(2828..4168)
                     /EC_number="2.5.1.19"
                     /GO_function="GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="aroA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674885.1"
                     /locus_tag="GR129_RS23295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_23295"
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="WP_145487204.1"
                     /transl_table=11
                     /translation="MAPNTASTALWPAPHASGAVDATVHVPGSKSVTNRALVLAALASE
                     PGWLRRPLRSRDTLLMAEALRAMGVEIEETVSSSSSVAGGPDGTGEAWRVLPTGLHGPA
                     TVDVGNAGTVMRFLPPVAALADGPIRFDGDPRSYERPLHGVIDALRRLGARIDDDGRGA
                     LPLTVHGGGALDGGPVSIDASSSSQFVSALLLSGPRFNQGVEVRHTGASLPSVPHIRMT
                     VDMLRAVGAQVDTPESGGEPNVWRVTPGALLGRDLTIEPDLSNAQPFLAAALVTGGKVL
                     VPDWPERTTQPGDRLREIFTEMGGACELTEFGLVFTGSGAIHGIDVDLGDVGELTPGIA
                     AVAALADSPSTLRGVAHLRLHETDRLAALTKEINELGGDVTETADGLHIRPRALHGGTF
                     HTYEDHRMATAGAIIGLAVEGVRIENIGTTAKTLPDFPELWTGMLGQ"
     misc_feature    complement(4170..4186)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.34"
                     /tool="antismash"
     misc_feature    4223..4242
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: medium, score: 24.93"
                     /tool="antismash"
     misc_feature    4226..4240
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 25.09"
                     /tool="antismash"
     gene            complement(4240..4962)
                     /locus_tag="GR129_RS23300"
                     /old_locus_tag="GR129_23300"
     CDS             complement(4240..4962)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992842.1"
                     /locus_tag="GR129_RS23300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_23300"
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_145487205.1"
                     /transl_table=11
                     /translation="MNSLAALAPSGLWDRLTGIQPDPDLWVVLATLAAALVVVVPHPLW
                     RVSRNAITIAHEGGHGLIALLTGRQLTGIRLHSDTSGLTVSRGKPYGLGMILTAAAGYI
                     APSLLGLGGAALLAAGRITLLLWAATALLAVMLVMIRNAYGVLTVVLAGGAFLLVSWLA
                     GPQVQAAFAYAVVWFLLFGGVRPPFELQSKRRRGEAGDSDADQLSRLTHVPAALWLFLF
                     HAVCLCSLIGGGRWLLEV"
     misc_feature    complement(4964..4978)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.88"
                     /tool="antismash"
     gene            5013..5828
                     /locus_tag="GR129_RS23305"
                     /old_locus_tag="GR129_23305"
     CDS             5013..5828
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0018142 - protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980380.1"
                     /locus_tag="GR129_RS23305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_23305"
                     /product="SOS response-associated peptidase"
                     /protein_id="WP_159704818.1"
                     /transl_table=11
                     /translation="MCGRYAASRGPEDLAKTFGIEKWEPEETLEPDYNVAPTKEVHVVL
                     DRPLKDADSPRPVRQLRTLRWGLVPSWSKTPEGAARMINARAETVHEKPSYRRAFAARR
                     CVVPADGYYEWVTGKQERDLEVEGRRKRPRKQPYFVLPADGSVFAMAGLYEFWRDRTLP
                     DDHPGAWWVTCSVITTEAERTPLAVAPADGPRSLADIHPRMPLMLTPDRWDAWLDPSRT
                     DPDELRALLAPPPPGLMRAYPVATAVSNVRNNGPELLKELEAPEEGTLF"
     gene            5830..6456
                     /locus_tag="GR129_RS23310"
                     /old_locus_tag="GR129_23310"
     CDS             5830..6456
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973757.1"
                     /locus_tag="GR129_RS23310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_23310"
                     /product="alpha/beta family hydrolase"
                     /protein_id="WP_159704821.1"
                     /transl_table=11
                     /translation="MIETVETDAGTARITWHRATAPRAVLALSHGAGGGIEARDLQALA
                     GVLPGHGVSVALVEQPWRVAGKRVAPAPRTLDTGWRGIWPALAGMELPVISGGRSAGAR
                     VACRTATGLGARAVLALSFPLHPPGRPEKSRADELLGTGVPTLVVQGGNDPFGKPAEFP
                     EGDFRMVEVPYGDHGFAVPRRAPTGQERALEIITDAVVEWTASLA"
     misc_feature    complement(5833..5847)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     gene            6713..7408
                     /gene="sigR"
                     /locus_tag="GR129_RS23315"
                     /old_locus_tag="GR129_23315"
     CDS             6713..7408
                     /codon_start=1
                     /gene="sigR"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973756.1"
                     /locus_tag="GR129_RS23315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_23315"
                     /product="RNA polymerase sigma factor SigR"
                     /protein_id="WP_167532282.1"
                     /transl_table=11
                     /translation="MGPVTGTDAGTDNGRAEEPEGRGTSAEASAESSAERSARFERDAL
                     EFLDQMYSAALRMTRNPADAEDLVQETYAKAYASFHQFREGTNLKAWLYRILTNTFINS
                     YRKKQREPQRSAAEEIEDWQLARAESHMSTGLRSAESQALDHLPDSDVKEALQAIPEEF
                     RIAVYLADVEGFAYKEIADIMGTPIGTVMSRLHRGRRQLRGMLEDYARERGLVPAGAGE
                     SDEAKGSGS"
     gene            7405..7707
                     /gene="rsrA"
                     /locus_tag="GR129_RS23320"
                     /old_locus_tag="GR129_23320"
     CDS             7405..7707
                     /GO_function="GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136687.1"
                     /locus_tag="GR129_RS23320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_23320"
                     /product="mycothiol system anti-sigma-R factor"
                     /protein_id="WP_037660188.1"
                     /transl_table=11
                     /translation="MSCGEPHETDCGEVLDHLYEFLDSEMPDVDRDKFRHHFEECSPCL
                     EKYGLEEAVKKLVKRCCGHDDVPADLRAKVMGRLDLIRSGQPAPDHDITSTAQDN"
     gene            7927..8907
                     /locus_tag="GR129_RS23325"
                     /old_locus_tag="GR129_23325"
     CDS             7927..8907
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889310.1"
                     /locus_tag="GR129_RS23325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_23325"
                     /product="hypothetical protein"
                     /protein_id="WP_128791613.1"
                     /transl_table=11
                     /translation="MRIFGKGRHRPSASWRQATDRAFTLIGDGRYEDAGELLTRAADLE
                     PWLSESWFNLALLHKFRHDWEQARAAGLRAVALLDRESGAPDWWNVGIAATALQDWPLA
                     RRAWQAYGLKVPGGATAAGEPLGMELGSAAVRLSPEGEAEVVWGRRLDPARIEVLSIPL
                     PSSGRRWGEVVLHDGVPHGERTTSAGHSYPVFDEIELWAPSPVPTWVVLLEAATEADRD
                     ALEQLAADAGFAAEDWSSSVRLLCRMCSESRMPSDEGEGEHLDPHDHSEPGHPGPLGHR
                     TDGQLWVPERECGVAAPPSLVRGLLDGWVADSPDSRDWRDLEEVC"
     gene            9060..9710
                     /gene="def"
                     /locus_tag="GR129_RS23330"
                     /old_locus_tag="GR129_23330"
     CDS             9060..9710
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983603.1"
                     /locus_tag="GR129_RS23330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_23330"
                     /product="peptide deformylase"
                     /protein_id="WP_145487209.1"
                     /transl_table=11
                     /translation="MAQQDTDQQHAGVLPVDDEGYVVDTEDCEGREKAWRESGTSRPIT
                     VVGNPVLHKECRDVTEFGEELRQLVADMFASQRTAEGVGLAANQIGVDLKVFVYDCQDD
                     EGARHVGVVCNPKLVDLPAERRRLDDNNEGCLSVPGAYAELARPDYAEVTGQDEQGNPV
                     KVRGTGYFARCLQHETDHLYGYLYIDRLSKRDRKDALRQMAENEPRYPVVAND"
     misc_feature    9800..9813
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.11"
                     /tool="antismash"
     misc_feature    complement(9855..9872)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     gene            10001..11086
                     /gene="cyc1"
                     /locus_tag="GR129_RS23335"
                     /old_locus_tag="GR129_23335"
     CDS             10001..11086
                     /EC_number="4.2.3.37"
                     /GO_function="GO:0052680 - epi-isozizaene synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cyc1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992851.1"
                     /locus_tag="GR129_RS23335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_23335"
                     /product="epi-isozizaene synthase"
                     /protein_id="WP_159704827.1"
                     /sec_met_domain="T1TS (E-value: 4e-62, bitscore: 209.6,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQAFPHRTTETTTAVVVPPSLALPVIESGFPRRLHPYWPRLQEKT
                     RLWLLEKQLMPEDKVREFADDLRYTDLMAGYYTDARDEVLQAIADYSAWFFVWDDRHDR
                     DIVHARLGDWRRLRHRLHAALDAPAHHLHHPDPLVAGFADSVLRLYGFLPVSWNQRFAR
                     HFHTVIEAYDREFRNRTQGYVPGVEEYLALRRLTFAHWIWTDLLEPSAGCELPDAIRRN
                     PAYRRAALLSQEFAAWYNDLCSLPKEIAGDEVHNLGISLITYEGLTLEEAVDNLRRRVE
                     TCIDEFLVAEREALRFADALADGTVRGKELSVAVRTCVGNMRNWFSSVYWFHHESGRYM
                     VDSWADRSTPPYVTNEAAGEK"
     gene            11083..12456
                     /locus_tag="GR129_RS23340"
                     /old_locus_tag="GR129_23340"
     CDS             11083..12456
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018544422.1"
                     /locus_tag="GR129_RS23340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_23340"
                     /product="cytochrome P450"
                     /protein_id="WP_145487211.1"
                     /sec_met_domain="p450 (E-value: 2.6e-69, bitscore: 232.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVESVQPETSVAPAQLREPPLAGGAVPVFGHGLQLVRDPLDFMS
                     SLRAHGDIVRLRLGPKTVYAVTTPELTGALALSPDFKIDGPVWESLVGLLGEEGVATAN
                     GPRHRRQRRTIQPAFRMDAIPDYGPIMEEEAHALTERWRPGAPIDCTSESFRVAVRMAA
                     RCLLRGEFMDERAERLSTDLATVFRGMYRRMVVPLGPLYKLPFPANREFNRALADLHLL
                     VDEIVAERRASGQKPDDLLTALLEAKDDNGEPIGEQEIHDQVVAIITPGAETIASTIMW
                     LLQALAEHPEHAEKVRAEVESVTGGRPVGFEHVRSLRHTNNVILEAIRLRPAVWILTRR
                     ATVDTALGEYRIPAGADIIYSPYAIQRDARSYDRHLDFDPDRWLPERAKEVPKYAMSPF
                     SVGNRKCPSDHFSMAQLSLITAAITAKYRFEPADDSDDSVRVGITLRPDNLRLRPLPW"
     gene            complement(12502..13464)
                     /locus_tag="GR129_RS23345"
                     /old_locus_tag="GR129_23345"
     CDS             complement(12502..13464)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018544423.1"
                     /locus_tag="GR129_RS23345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_23345"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_159704830.1"
                     /transl_table=11
                     /translation="MLKNVAAVLLDGVHPFELGVVCEVFGIDRSDEGLPVYDFAVVSAE
                     GPDLGTHCGFTVSTPHGLERLEEADLIAVPAGESYVDRDYPPELLAALRRAVERGCRVL
                     SVCSGVFVLAAAGLLDGRRCAVHWHHAEQLARRHPRLAVEQDVLYVDEDPVITSAGTAA
                     GIDACLHLVRKEQGPEVANKIARRMVVPPHRDGGQAQYIERPLPRTPCDTVGEVLVWME
                     EHLDREVTVEQLAARAHMAPRTFARRFQQETGTTPYRWILRQRVLRAQELLEGTGETVD
                     AIAARTGFGTAAALRHQFMRALGTTPNAYRRAFRGPQAA"
     gene            complement(13479..13697)
                     /locus_tag="GR129_RS35360"
     CDS             complement(13479..13697)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GR129_RS35360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_201300659.1"
                     /transl_table=11
                     /translation="MVLLGLPDLPVDAPLAQDAEHGGKGQEDEDPEGRGHSDQALDLVS
                     GHVTTVLPDTADREWQDCRAPSNYCQP"
     gene            complement(13712..14725)
                     /locus_tag="GR129_RS23355"
                     /old_locus_tag="GR129_23355"
     CDS             complement(13712..14725)
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674901.1"
                     /locus_tag="GR129_RS23355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_23355"
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_145487214.1"
                     /transl_table=11
                     /translation="MSTRHQNLLDPGFELTLRPMRYPDFYERYRDAIKNTWTVEEVDLH
                     SDVSDLAKLSPAEQHLIGRLVAFFATGDSIVANNLVLTLYKHINSPEARLYLSRQLFEE
                     AVHVQFYLTLLDTYLPDPEDRAAAFAAVENIPSIREKAEFCFKWIDSVDKIDRLESKSD
                     RRRFLLNLICFAACIEGLFFYGAFAYVYWFRSRGLLHGLATGTNWVFRDETMHMSFAFD
                     VVDTVRKEEPELFDDQLQQEVTDMLREAVEAELQFARDLCGDGLPGMNTDSMRQYLECV
                     ADQRLSRLGFAPVYGSENPFSFMELQGVQELTNFFERRPSAYQVAVEGKVDLDEDF"
     gene            complement(14725..17082)
                     /locus_tag="GR129_RS23360"
                     /old_locus_tag="GR129_23360"
     CDS             complement(14725..17082)
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674902.1"
                     /locus_tag="GR129_RS23360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_23360"
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="WP_159704836.1"
                     /transl_table=11
                     /translation="MTIAPAEPASAQGLENDGPGTALLRTLTELTGDLPDADPGRVAAA
                     ALRGRSAHADEAELRELATEAAAGLISEDPAYSRLAARLLTISIRAEAASQGVASFTES
                     VAVGHREGLIADRTAEFVRIHAARLDHLIDRAADDRFGYFGLRTLHSRYLLRHPITRQV
                     IETPQHFMLRVAAGLAEDDSARSVDEVAALYRLMSRLDYLPSSPTLFNSGTRHPQMSSC
                     YLLDSPLDELDSIYDRYHQVARLSKHAGGIGLSYSRIRARGSLIRGTNGHSNGIVPFLK
                     TLDASVAAVNQGGRRKGAAAVYLETWHSDLEEFLELRDNTGEDARRTHNLNLAHWVPDE
                     FMRRVNADGQWSLFSPADVPELVDLYGAEFDAAYREAERKGLAKKTMPARELYGRMMRT
                     LAQTGQGWMTFKDAANRTANQTAEPGQVIHSSNLCTEILEVTNDGETAVCNLGSVNLGA
                     FVVDGDIDWARLDETVHTAVTFLDRVVDINFYPTEQAGRSNAKWRPVGLGAMGLQDVFF
                     KLRLPFDSPEAKALSTKIAERIMLAAYEASADLAERSGPLPAWEQTRTARGVLHPDHYG
                     VEETWPERWAALRKRIAEVGLRNSLLLAIAPTATIASIAGVYECIEPQVSNLFKRETLS
                     GEFLQVNSYLVQDLKGLGVWDARTREALREANGSVQGFAWIPEEVRALYRTAWEIPQRG
                     LIDMAAARTPFLDQAQSLNLFMETPTIGKLSSMYAYAWKSGLKTTYYLRSRPATRIARA
                     AQAQQTIPVQQVADPDAVACSLENPESCEACQ"
     regulatory      complement(17205..17340)
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    17239..17256
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     misc_feature    complement(17327..17341)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 23.4"
                     /tool="antismash"
     misc_feature    complement(17358..17372)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: strong, score: 25.12"
                     /tool="antismash"
     gene            complement(17490..19118)
                     /locus_tag="GR129_RS23365"
                     /old_locus_tag="GR129_23365"
     CDS             complement(17490..19118)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674905.1"
                     /locus_tag="GR129_RS23365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_23365"
                     /product="sodium:solute symporter family protein"
                     /protein_id="WP_145487216.1"
                     /transl_table=11
                     /translation="MKTGVNGVALGVFIFFFLAVTVLGFLAARWRRAENEHTLDEWGLG
                     GRSFGTWITWFLLGGDLYTAYTFVAVPAAIYAAGASGFFAVPYTILVYPLIFTFLPRLW
                     SVSHRHGYVTTSDFVRGRFGSKGLSLAVAVTGILATMPYIALQLVGIQAVLDVMGVGGG
                     DNTNAFVKDLPLLIAFAVLAAYTYSSGLRAPALIAFVKDALIYIVIGVAIIYIPIKLGG
                     FDDIFAKAAHAFSQVNPATGKPRGALAPAPAGQWTYATLALGSALALFMYPHSITATLS
                     SKSRNVIRRNTTILPLYSLMLGLLALLGFMAIAAGVKVTNGQLAIPQLFEDMFPDWFAG
                     VAFAAIGIGALVPAAIMSIAAANLFTRNIYKDFIKPDATPKQEAQVSKFVSLLVKVGAL
                     IFVLGMDKTVAINFQLLGGIWILQTFPALVGGLFTRWFHRWALLAGWAVGMIYGTLAAY
                     GVASPTQKHFGGSADDIPGIGQIGYIGMTAFVLNVLVTVVLTVVLKAVKAPEGIDETRP
                     EDYTADAGDPGVQVELPPATAGTSH"
     gene            complement(19115..19378)
                     /locus_tag="GR129_RS23370"
                     /old_locus_tag="GR129_23370"
     CDS             complement(19115..19378)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992859.1"
                     /locus_tag="GR129_RS23370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_23370"
                     /product="DUF3311 domain-containing protein"
                     /protein_id="WP_186337848.1"
                     /transl_table=11
                     /translation="MSETPEVGPPVVTPLRVVIGICLVAPFVAMLWVGSYAKTDPTFIG
                     IPFFYWYQMVWVLISTALTMTAYKLWQHDQRSRRDAQGGAAK"
     gene            complement(19513..20277)
                     /locus_tag="GR129_RS23375"
                     /old_locus_tag="GR129_23375"
     CDS             complement(19513..20277)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973740.1"
                     /locus_tag="GR129_RS23375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR129_23375"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_037660203.1"
                     /transl_table=11
                     /translation="MSTDVSSAENEAGTTVRTARVPKYYRLKKHLLDMTETQAPGTPVP
                     PERTLAAEFDTSRTTVRQALQELVVEGRLERIQGKGTFVAKPKVSQALQLTSYTEDMRA
                     QGLEPTSQLLDVGYITADDRLAGLLDISAGGRVLRIERLRMANGEPMAIETTHLSAKRF
                     PALRRSLVKYTSLYTALAEVYDVHLAEAEETIETSLATPREAGLLGTDVGLPMLMLSRH
                     SLDRAGLPVEWVRSVYRGDRYKFVARLKRPMD"
     misc_feature    20299..20314
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.61"
                     /tool="antismash"
     misc_feature    20413..20428
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 21.06"
                     /tool="antismash"
ORIGIN
        1 agacatggat gcggctcgcg gaggtcagat tgcggccggt gaaggcgccg tggcccttgg
       61 cggcccacca gcggcggccg agcgcggggg cggagacgag gcccacgacc gggtggtggc
      121 ccccctcgcc cgcctccatc agcgagatca gcgtggccca caccgggacg ccgcgcacgt
      181 agttcttggt gccgtcgatc gggtcgatca cccagcgccg ggggccggtg ccctcggcgc
      241 cgtactcctc gccgaggacc gagtctctgg gacgggcgcg ctggagctgg ccgcggatca
      301 gttcctcggc cgccttgtcc gcttcgctca ccggcgtcat gtccggcttc gtctcgacct
      361 tcaggtccag ggccttgaag cggtccatgg tgatggcgtc ggccgcgtcc gcgaggacat
      421 gggcgagacg gaggtcgtcg aggtagtcgg gcatgtacgt cacgctatcg gctgagcggg
      481 tacgggagcc accgggggcg tgcgcgtgtc gagccggccg tgcgcggcgc ccgcgcgggc
      541 gtgggcggcg gtcgcgcgtc cgcacgcggt gggcgggctt ccgctcccgg cgggagaccc
      601 cttgacatca tccgaaagtc cgtcaaatct gggcggaacg ccgttgactc cagggagacg
      661 acgatggccg ctgcccggga atccttgctg gacgccgctg tcgcggcgct ggcgcgccgg
      721 ccgtggccga cggtgcgcat ggtggaggtg gccgcgtcgg cgggcgtgtc ccggcagacc
      781 ctgtacaacg agttcggcgg caaggccggc ctcgcgcggg cgctggtgcg gcgggcggcc
      841 gacggctatc tcgccggtgt ggagcgcgcg ctcgcgggtg gtggcggcga ctgggagcgg
      901 ctcaccgccg tcgccgagtg gacggcgggc gcggcccagg aggacgcgct ggtacgggcg
      961 ttgctcaccg gctgctggag cgagcggctc cccgcgccgc accggggccc gtccccggta
     1021 ccggcaccgc gccgcccgga acggccgctc ccctcgcccc ccgacctcgt acggctggtc
     1081 cgcgaccgcg ccgtcaccgc gctgtccggc cccggcacgg gccccgccgc caccgccgaa
     1141 ctggcccgct cctgcgaact ggtcctccgc ctcgccctct cctgcgtcac agccccaccg
     1201 gccgagggcg gcctccccgc actgctccgc tccctcgcac cccgcacaac actctgaccg
     1261 acgccaaccg ccgtcagtac gtggtgcttc gggcgccccg cacagtgggt ccgcaaccag
     1321 agcgtccggc gacggaacgg ctcccgcgtg ccgcccagtc gaacggtggc cggcccaccg
     1381 cccggcacgc agcgggcgcc tagtggctcg accccgacag ttgcaggccg atgattccca
     1441 cgatcacgaa gctgatcgag atgatcttca gggtggagac caggtcgccc aggaagatca
     1501 tgccgtagat cgccgtgccg gtcgcgccga tgccggtcca gacggcgtac gcggggccga
     1561 cgtcgagttt gcgcagggag agggtcagca ggccgaagct gccgagggcg aaggaggcga
     1621 aggcgatggt cggccacagg cgggtgaagc cgtgggagag cttgaggcac acggcgaagc
     1681 cggtctccag cattccggcc acgatgacca gcagccacgc catgcgctgt cctcccgttg
     1741 atccggatct ccggcccggt gcgattatgc acttgccgca ccgtggcccg ggcaaacaac
     1801 gcgaaggtca gtcgccttcc gtgcgctccc gcgtcgccag cagccgccgc agcgagtaca
     1861 gccgcgccgg atccgcgtgc cccgcctcca cccacgcgtc cagcgcgcag tccggctcgt
     1921 cgtggccgca cgcgcgcggg cagtccgccg taccgggctc caggtccggg aaggcgtgga
     1981 tgacccggga cggatcgatg tgcgccaggc cgaaggaccg tacacccgga gtgtcgacca
     2041 cccagccgtc gtcgcccgcc agcggcagcg ccagcgccga cgtggtggtg tgccggccgc
     2101 gccccgtcac cgcgttgacg tgtcccgtcg tgcgccgccg ctcctccggg accagcgcgt
     2161 tcaccagcgt cgtcttgccc acgccggagt gccccacgaa cgccgtgatc cgcccgtcca
     2221 ggaactcccg cacccggtcc gccgcgtccc cgttctccag ctcctcgcgg ctggtgacca
     2281 cgtacgggat gtccagatgg ccgtacagct cgaggagttc gtccggtgcg gccaggtccg
     2341 acttggtcag caccagcagg ggttcgagcc ccccgtcgta cgccgcgacc aggcagcggt
     2401 cgatcagccg gggccgcggc tcggggtcgg cgagggccgt gacgatcgcc agctggtcgg
     2461 cgttggcgac caccacgcgc tcgtaggggt cgtcgtcgtc cgccgtgcgc cgcagcaccg
     2521 acgtccgctc ctggatccgg acgatccgcg cgagcgtgtc cttcttgccg gacagatcgc
     2581 cgaccagcat cacccggtcc ccgaccaccg ccgccttgcg gcccagctcc cgcgccttca
     2641 tcgccatcac cacccggtcc tccaccaggc aggtcagccg cccccggtcc acggtcagga
     2701 ccaggccctc ggccgcgtcc tcgtgcttgg gccggatgtg cgtccgcggc cggttgccct
     2761 tgcggttggg gcgggagcgg atgtcgtcct cgtcggtgtt cttgccgtag cggcgcatgg
     2821 cgtgtcccta ctgcccgagc atcccggtcc acagctcggg gaagtccggc agggtcttgg
     2881 ccgtcgtccc gatgttctcg atgcgtacgc cctcgaccgc caggccgatg atcgcgccgg
     2941 cggtggccat gcggtggtcc tcgtaggtgt ggaaggtgcc gccgtgcaga gcgcgcgggc
     3001 ggatgtgcag accgtcggcc gtctccgtga cgtcgccgcc gagctcgttg atctccttgg
     3061 tgagcgcggc gagccggtcc gtctcgtgca gccgcagatg ggccaccccg cgcagcgtcg
     3121 agggggagtc ggcgagcgcg gcgacggccg cgatgcccgg ggtcagctcg ccgacgtcgc
     3181 ccaggtcgac gtcgatgccg tggatcgcgc cggaaccggt gaacaccagc ccgaactcgg
     3241 tgagttcgca ggcgccgccc atctcggtga agatctcgcg cagccggtca cccggctggg
     3301 tggtgcgctc cggccagtcc gggaccagca ccttgccgcc ggtgaccagg gccgccgcca
     3361 ggaacggctg cgcgttggac aggtccggct cgatcgtcag gtcccggccg agcagcgcgc
     3421 ccggcgtcac ccgccatacg ttcggctcgc cgcccgactc cggggtgtcc acctgggcgc
     3481 cgaccgcgcg cagcatgtcc accgtcatcc ggatgtgcgg cacggacggc aggctggcgc
     3541 cggtgtgccg gacctcgacg ccctggttga agcgggggcc cgagagcagc agcgcggaga
     3601 cgaactgcga ggaggaggac gcgtcgatcg acaccgggcc gccgtccagc gccccgccgc
     3661 cgtgcacggt cagcggcagc gcgccccggc cgtcgtcgtc gatccgcgcg ccgagccggc
     3721 gcagcgcgtc gatcacgccg tgcagcggac gctcgtacga ccgcgggtcg ccgtcgaacc
     3781 ggatggggcc gtcggccagc gcggccaccg gcggcaggaa gcgcatcacg gtgcccgcgt
     3841 tgccgacgtc cacggtggcc gggccgtgca ggccggtcgg cagcacccgc caggcctcgc
     3901 cggtgccgtc cgggccgccc gcgacggagg agctggacga caccgtctcc tcgatctcca
     3961 cgcccatggc ccggagggcc tccgccatca gcagggtgtc ccgggagcgc agcgggcggc
     4021 gcagccagcc gggctcggag gcgagggcgg ccagcaccag ggcgcggttg gtgaccgact
     4081 tggaccccgg cacatggacg gtggcgtcga cggctccgct cgcgtgcgga gcgggccaga
     4141 gggcggtgga ggcggtgttc ggggccatgg gcccacttta taaggagggc ggggccgcaa
     4201 ccttccggcg acgggcccgc cgtccgggac gaacggccct cagacctcca gcagccagcg
     4261 cccgccgccg atcagcgagc acaggcacac ggcgtggaag aggaacagcc acagggccgc
     4321 cgggacgtgc gtcagccggg acagctggtc cgcgtccgag tcgccggcct cgccccggcg
     4381 gcgcttgctc tgcagctcga acggcggccg tacgcccccg aacagcagga accacaccac
     4441 cgcgtacgcg aacgccgcct gcacctgcgg ccccgcgagc cacgacacca gcaggaacgc
     4501 cccgcccgcg agcaccacgg tgagcacgcc gtacgcgttg cggatcatca ccagcatcac
     4561 cgcgagcagg gccgtcgccg cccacagcag cagcgtgatg cggcccgcgg cgagcagggc
     4621 cgcgccgccg aggccgagca gcgagggcgc gatgtagccc gcggccgcgg tgaggatcat
     4681 gccgagcccg tacggcttgc cccggctcac cgtgagcccg ctggtgtcgg agtgcagccg
     4741 gatcccggtg agctgccggc cggtgagcag ggcgatgagc ccgtggccgc cctcgtgcgc
     4801 gatggtgatc gcgttgcgcg acacccgcca cagcggatgc ggtaccacca ccaccagcgc
     4861 ggcggcgagg gtggcgagca ccacccacag atcggggtcg ggctggatac cggtgagccg
     4921 gtcccagagg ccggacggcg cgagggcggc gaggctgttc atgtgtccga gtggctccct
     4981 ggtggcgggc ggagtctggc agtgtggcac gtatgtgcgg acggtatgca gccagtcgtg
     5041 ggcccgagga cctcgccaag accttcggga tcgagaagtg ggaacccgag gagaccctgg
     5101 agccggacta caacgtggcc cccaccaaag aggtccacgt cgtgctcgac cgccctttga
     5161 aagacgcgga ctccccgcgt ccggttcgcc agctgcgcac actcaggtgg ggactggtgc
     5221 cgtcctggtc gaagaccccc gagggcgccg cccggatgat caacgcccgt gcggagaccg
     5281 tgcacgagaa gccgtcctac cgccgtgcct tcgccgcccg ccgctgcgtc gtgcccgccg
     5341 acggctacta cgagtgggtg accgggaagc aggagcggga cctggaggtc gaggggcgca
     5401 ggaagcggcc gcgcaagcag ccgtacttcg tactgcccgc cgacggctcc gtgttcgcga
     5461 tggccggcct gtacgagttc tggcgcgacc gcaccctgcc cgacgaccac cccggcgcct
     5521 ggtgggtcac ctgctcggtg atcaccacgg aggccgagcg gaccccgctg gccgtcgccc
     5581 ccgccgacgg accgcgctcg ctcgccgaca tccacccccg gatgccgctg atgctcaccc
     5641 cggaccgctg ggacgcctgg ctggacccct cccgcaccga cccggacgag ctgcgcgccc
     5701 tgctcgcccc gcccccgccc ggcctgatgc gcgcctaccc ggtcgccacc gccgtcagca
     5761 acgtccgcaa caacggcccc gagctgctga aggagctgga ggccccggaa gagggcacac
     5821 tcttctagcg tgatcgagac cgttgagacc gacgccggaa ccgcccgcat cacctggcac
     5881 cgggccacgg ccccccgggc cgtcctcgcg ctgagccatg gcgcgggcgg cggtatcgag
     5941 gcgcgtgacc tccaggcgct cgccggggtc ctgcccgggc acggggtgag cgtggccctc
     6001 gtggaacagc cctggcgggt cgcgggcaag cgggtggcgc ccgcccccag gacgctggac
     6061 accggatggc gcgggatctg gcccgcgctg gccggcatgg agctgccggt gatctccggc
     6121 ggccgcagcg ccggcgcccg cgtcgcctgc cgcaccgcca ccggactggg agcccgcgcc
     6181 gtcctcgccc tgagcttccc gctgcacccg ccgggcaggc ccgagaagtc ccgcgcggac
     6241 gaactgctgg gcaccggcgt gcccaccctc gtcgtccagg gcggcaacga ccccttcggc
     6301 aagcccgccg agttccccga gggcgacttc cggatggtcg aggtgccgta cggcgaccac
     6361 ggcttcgcgg tccccagacg cgcgccgacc ggccaggaac gggccctgga gatcatcacc
     6421 gacgccgtcg tggagtggac cgcgtcactc gcgtgacccc cgggaatgct gcgcggcgca
     6481 gcgctgttgt gacgcacagg agtgctgagg cctcggcacc gacgtcgtcg gaagggaagt
     6541 ccgccgcatg ggttcgacca tctgcccggc ccgtcagacc ggcgctgagc tggactggac
     6601 ggtgctgcgc gcgcccaaga ccgcctcaat tcgaggggcg gcgggtacgg gtcgtgttct
     6661 atcctccgaa tcgagtggga ccactctcgg tcctgcccgg gatcttgagg aggtgggtcc
     6721 ggtcacaggg accgacgcgg ggaccgacaa cggccgggcg gaagagcccg agggccgggg
     6781 cacgagcgcg gaggcgtccg ccgagtcgag cgcggagcgc agcgcgcgct tcgagcggga
     6841 cgcgctcgag ttcctcgacc agatgtactc ggccgccctg cgcatgacgc gcaacccggc
     6901 cgacgccgag gacctcgtgc aggagacgta cgccaaggcc tacgcctcct tccaccagtt
     6961 ccgcgagggc accaacctca aggcgtggct gtaccggatc ctcaccaaca ccttcatcaa
     7021 ctcgtaccgc aagaagcagc gtgagcccca gcgctccgcc gcggaggaga tcgaggactg
     7081 gcagctcgcc cgggccgagt cgcacatgtc gacggggctg cgctccgccg agtcgcaggc
     7141 gctcgatcat ctgcccgact cggatgtgaa ggaagcgctc caggcgatcc ccgaggagtt
     7201 ccgcatcgcc gtgtatctcg cggatgtgga ggggtttgcc tacaaggaga tcgcggacat
     7261 catggggaca cccatcggta cggtgatgtc ccggctgcac cggggccgcc gtcaactgcg
     7321 cggcatgctg gaggactacg cccgtgagcg cgggctggtc ccggcgggcg ccggggagtc
     7381 ggacgaagcg aaaggctcgg gctcatgagc tgcggagagc cgcacgagac ggactgcggt
     7441 gaggtcctcg accatctgta cgagttcctc gacagcgaga tgccggacgt cgaccgcgac
     7501 aagttccggc accacttcga ggaatgctcg ccgtgcctgg agaagtacgg cctggaagag
     7561 gccgtgaaga agctggtcaa gcggtgctgc ggccatgacg acgtgcccgc ggacctgcgt
     7621 gccaaggtca tgggccggct ggacctgatc cgctccggac agcccgcgcc cgaccacgac
     7681 atcacctcca cggcccagga caactgagcc cacgcgccgc acgcgccccg caccctcccg
     7741 tcgagccccg cccggccccg ccgtcggcgc gggcgagacg tacggcactg tctgatcccg
     7801 cccgcacctg ggtaacccat gggtaatgag cgccgttccc accgcacgtg gttggatgcg
     7861 agggagaggg cgcctggggg cacaagccag cccactgtgc ggaactggaa ctggcaggcg
     7921 ggaatcgtga ggatcttcgg caagggacgg caccgaccct ccgcctcctg gcggcaggcc
     7981 accgaccgcg cgttcacgct catcggcgac ggccggtacg aggacgcggg cgaactgctg
     8041 acccgcgccg ccgacctgga accctggctg tcggagtcct ggttcaacct cgcgctgctg
     8101 cacaagttcc ggcacgactg ggagcaggcc cgcgccgccg gactgcgcgc cgtcgccctg
     8161 ctcgaccgcg agagcggcgc ccccgactgg tggaacgtgg gcatcgccgc gaccgccctc
     8221 caggactggc cgctggcccg ccgcgcctgg caggcgtacg gcctgaaggt gcccgggggc
     8281 gcgaccgccg ccggggaacc gctcggcatg gagctgggca gcgcggccgt acggctctcg
     8341 cccgagggcg aggccgaggt ggtgtggggc cgccggctgg accccgcgcg gatcgaggtg
     8401 ctgtccatcc cgctgccctc ctcggggcgg cgctggggcg aggtcgtgct gcacgacgga
     8461 gtcccgcacg gggagcgcac cacgtccgcc gggcacagtt accccgtctt cgacgagatc
     8521 gagctgtggg cgccctcgcc cgtgcccacc tgggtggtgc tcctggaggc ggccaccgag
     8581 gcggaccggg acgcgctgga gcagctggcc gcggacgccg ggttcgccgc ggaggactgg
     8641 tcgtcctcgg tgcggctgct gtgccggatg tgcagcgagt cccggatgcc gtccgacgag
     8701 ggcgaggggg agcacctgga cccccacgac cacagcgaac ccggccaccc gggccccctg
     8761 ggccaccgca cggacggcca gctgtgggtg ccggagcggg agtgcggggt ggccgcgccg
     8821 ccttcgctgg tccgggggct gctggacggc tgggtcgccg acagcccgga ctcgcgggac
     8881 tggcgggatc tcgaagaggt gtgctgagca gctcgttcgg ctgattcgcc gtcgtggctg
     8941 atcgcgcaca cgcggcggag ccgcatatca gacactgacc cgcccccctc cggggcgcgt
     9001 ccgcgtaccc tgtatcagca ttcactccca gttcttgtgc aggaaggcgt acgtcggtca
     9061 tggcgcagca ggacaccgat cagcagcacg cgggcgtgct ccccgtcgac gacgagggct
     9121 atgtcgtgga cacggaggac tgcgaggggc gcgagaaggc ctggcgggag agtggcacct
     9181 cgcggccgat cacggtcgtc ggcaatccgg tgctgcacaa ggagtgccgg gacgtcaccg
     9241 agttcggcga ggaactgcgg cagctggtcg ccgacatgtt cgccagccag cgcaccgccg
     9301 agggcgtggg cctggccgcc aaccagatcg gcgtcgacct gaaggtcttc gtctacgact
     9361 gccaggacga cgagggcgcc cggcacgtgg gcgtggtgtg caacccgaag ctggtcgacc
     9421 tgcccgccga gcggcgccgg ctcgacgaca acaacgaggg ctgcctgtcg gtgcccgggg
     9481 cctacgccga gctggcgcgc cccgactacg ccgaggtgac cggccaggac gagcagggca
     9541 acccggtcaa ggtccgcggc accggatact tcgcacggtg tttgcagcac gagaccgacc
     9601 acctctacgg ctacctctac atcgaccggc tgtccaagcg cgaccgcaag gacgcgctgc
     9661 ggcagatggc cgagaacgag ccgcgctacc ccgtggtcgc caacgactag gtcccgtggg
     9721 gccgttgggc gccgtaccgg gaaccagtcc cggcccggcg cccttcttct tgcccttctt
     9781 cgttcaccag tacgtcgcac aaatggtcgt ttctgcggtg ctggtgatca ttaatcagtc
     9841 acacagggga ggaatctcgg caccatgggg tagtgagggg cgcaaatccg ttcccacggc
     9901 ggtcagttgt ggtgctgaat gggaagtgcg ggataggtaa cgagacgcac cggtcccacc
     9961 cgagcgggtg cgtatccggc ggctgagagg ggtttgttcc gtgcaggctt tcccacaccg
    10021 caccacagag acgacgacgg cggtcgtggt accaccctcg ctggcactcc cggtgatcga
    10081 gtccggcttt ccccggcgac tgcacccgta ttggccgcgg ctccaggaga agacccggct
    10141 gtggctgctg gaaaagcagc tgatgccgga ggacaaggtg cgggagttcg ccgacgatct
    10201 gcgctacacc gacctgatgg cgggctacta cacggacgcc cgcgacgagg tgctccaggc
    10261 gatagcggac tacagcgcct ggttcttcgt ctgggacgac cggcacgacc gcgacatcgt
    10321 gcacgcgcgc ctgggcgact ggcggcggct gcgccaccgg ctgcacgcgg cactcgacgc
    10381 acccgcgcac catctgcacc acccggaccc gctggtcgcg ggattcgccg acagcgtgct
    10441 gcggctctac ggcttcctgc cggtcagctg gaaccagcgc ttcgcccggc atttccacac
    10501 ggtcatcgag gcgtacgacc gtgaattccg caatcgcacc caggggtatg tgcccggcgt
    10561 cgaggagtat ctcgccctgc gccggctcac cttcgcgcac tggatctgga ccgaccttct
    10621 cgaacccagt gccggatgtg aactccccga tgccataagg aggaatcccg cttatcgccg
    10681 ggccgccttg ctcagtcagg aattcgccgc ctggtacaac gatctgtgct cgctcccgaa
    10741 ggaaatagca ggcgatgagg tccacaatct cggaatcagt ctcatcacct acgaggggct
    10801 gactctcgaa gaggcggtgg acaatctcag gcggcgcgtc gagacctgca tcgacgaatt
    10861 cctcgtagcc gaacgcgaag ccctccggtt cgcggatgca ctcgccgacg gtacggtacg
    10921 cggaaaggaa ttgagcgtcg ccgtccgcac ctgcgtcggc aatatgcgca actggttcag
    10981 ctcggtctac tggttccacc acgagtccgg ccgttacatg gtggacagtt gggccgaccg
    11041 ctccacaccc ccgtacgtca ccaacgaagc ggcaggtgag aaatgaccgt agagtccgtg
    11101 cagcccgaga cctccgtcgc cccggcgcag ctgcgtgaac cacccctggc cggcggcgcc
    11161 gtcccggtct tcgggcacgg cctgcaactg gtgcgcgacc cgctggactt catgtcctcg
    11221 ctgcgcgccc acggcgacat cgtgcgtctc aggctcggcc ccaagaccgt gtacgccgtc
    11281 accaccccgg agctgaccgg cgcgctcgcc ctcagccccg acttcaagat cgacggcccg
    11341 gtgtgggagt cgctggtggg cctgctcggc gaggagggcg tggccacggc caacggcccc
    11401 cgccaccgca ggcagcggcg caccatccag cccgcgttcc ggatggacgc catacccgac
    11461 tacggcccga tcatggagga ggaggcgcac gcgctgaccg agcgctggcg gcccggcgcc
    11521 cccatcgact gcacctcgga gtccttccgg gtggccgtgc gcatggcggc ccgctgcctg
    11581 ctgcgcggcg agttcatgga cgagcgcgcc gagcggctga gcaccgacct cgccaccgtc
    11641 ttccgcggta tgtaccgcag gatggtggtg ccgctggggc ccctgtacaa gctgccgttt
    11701 ccggccaatc gtgaattcaa ccgcgcattg gccgatttgc atctgctggt ggacgagatc
    11761 gtcgccgagc ggagggcatc tggtcaaaag ccggacgatt tgctgacggc attgctggag
    11821 gcgaaggacg acaatgggga gcccatcggg gaacaggaga tccacgacca ggtcgtcgcg
    11881 ataatcaccc ccggcgccga aacgatcgcg tccacgatca tgtggctgct ccaggcgctc
    11941 gcggaacacc cggagcatgc cgagaaggtg cgtgccgagg tcgaatccgt gaccggcggc
    12001 cggcccgtcg gattcgagca cgtccgctcc ctcaggcaca ccaacaatgt gatcctggag
    12061 gccatccggc tgcgcccggc cgtatggatt ctgacgcgcc gggcgaccgt cgacaccgcg
    12121 ctcggggagt accgcattcc ggccggggcc gacatcatct acagcccgta cgccattcag
    12181 cgcgacgccc gttcgtacga ccggcatctc gacttcgacc cggaccgctg gcttccggaa
    12241 cgggccaagg aggtgccgaa gtacgcgatg agccccttca gcgtcggcaa ccgcaagtgc
    12301 cccagcgacc acttctccat ggcccagctg agcctgatca ccgcggcgat cacggcgaag
    12361 taccgcttcg aaccggcgga cgacagcgac gacagcgtcc gggtgggcat caccctgcgc
    12421 ccggacaatc tgcggctgcg gccgctgccc tggtgagaca ccccgggtga caccaggagc
    12481 gatgccgcta ccggcgcgtg ttcaggcggc ctgcgggccc cggaacgcgc gccggtaggc
    12541 gttcggggtg gtaccgagcg cccgcatgaa ctggtggcgc agcgcggccg ccgtaccgaa
    12601 cccggtgcgc gcggcgatcg cgtccaccgt ctcgccggtg ccctccagca actcctgtgc
    12661 gcgcagcacc cgttggcgca ggatccagcg gtacggcgtg gtccccgtct cctgctggaa
    12721 gcggcgggcg aaggtgcgcg gcgccatatg ggcgcgggcg gcgagctgtt cgacggtcac
    12781 ctcccgatcg aggtgctcct ccatccacac cagcacctcg ccgacggtgt cgcacggcgt
    12841 cctgggcagc ggccgttcga tgtactgggc ctggccgccg tcccggtgcg ggggcaccac
    12901 catccggcgg gcgatcttgt tggcgacctc ggggccctgc tccttgcgca ccagatgcag
    12961 acaggcgtcg atgccggccg cggtgcccgc ggaggtgatc accgggtcct cgtccacata
    13021 gagcacgtcc tgctcgacgg cgagccgcgg atggcgccgg gccagctgct cggcatggtg
    13081 ccagtgcacc gcgcaccggc gcccgtccag cagcccggcg gcggccagca cgaacacccc
    13141 ggagcagacg ctgagcaccc ggcagccccg ctcgacggcc cgccgcagcg ccgcgagcag
    13201 ctcgggcgga tagtcccggt ccacatagct ctcaccggca ggtacggcga tcagatcggc
    13261 ctcttccagc cgctccaggc cgtgcggcgt ggacacggtg aacccgcagt gcgtgccgag
    13321 gtcgggcccc tcggccgaga ccacggcgaa gtcgtacacc ggcagcccct cgtcgctgcg
    13381 gtcgatgccg aacacctcgc agacgacgcc cagctcgaag gggtgcactc cgtccagcag
    13441 cacggcggcc acgttcttga gcatgccccc agtgtgcctc agggctggca gtaattcgag
    13501 ggtgcccggc agtcctgcca ctcccggtca gcagtgtccg gcaggacagt ggtgacatga
    13561 ccggaaacca gatccaaggc ctgatcggaa tgaccgcgac cctcgggatc ctcgtcctcc
    13621 tggcccttcc ctccgtgctc ggcgtcctgc gcgagcggcg cgtcgaccgg cagatcagga
    13681 aggcccagga ggaccacgga aagaaggagg ctcagaagtc ctcgtccagg tcgaccttgc
    13741 cctccaccgc cacctggtac gccgacgggc ggcgctcgaa gaagttggtc agctcctgaa
    13801 caccctggag ctccatgaag gagaaggggt tctccgaacc gtagaccggc gcgaagccca
    13861 gccgggacag gcgctggtcg gccacgcact ccaggtactg ccgcatggag tcggtgttca
    13921 tgcccgggag gccgtcaccg cacaggtcgc gcgcgaactg cagctcggcc tcgacggcct
    13981 cccgcagcat gtcggtgacc tcctgctgga gctggtcgtc gaacagctcc ggctcctcct
    14041 tgcgcacggt gtcgaccacg tcgaaggcga aggacatgtg catcgtctcg tcgcggaaca
    14101 cccagttggt gccggtggcc aggccgtgca gcagaccccg gctgcggaac cagtagacgt
    14161 acgcgaaggc gccgtagaag aacaggccct cgatgcacgc ggcgaagcag atcaggttga
    14221 gcaggaagcg ccggcggtcc gacttcgact ccagccggtc gatcttgtcc accgagtcga
    14281 tccacttgaa gcagaactcg gccttctcgc ggatcgaggg gatgttctcg acggccgcga
    14341 acgccgccgc gcggtcctcc gggtcgggca ggtaggtgtc cagcagcgtc agatagaact
    14401 ggacgtgcac cgcctcctcg aacagctgac ggctcaggta cagccgcgcc tcaggggagt
    14461 tgatgtgctt gtacagcgtc agcaccaggt tgttggcgac gatcgagtca cccgtcgcga
    14521 agaacgcgac caggcggccg atcaggtgct gctcggccgg gctcagcttc gcgaggtcgg
    14581 agacgtccga gtggaggtcg acctcctcca cggtccaggt gttcttgatg gcgtcccggt
    14641 agcgctcgta gaagtccggg tagcgcatcg gacggagagt cagttcgaag cccgggtcga
    14701 gcaggttctg atgacgggtg gacattactg gcaggcctcg caggactcgg ggttttccag
    14761 ggagcaggcg acggcgtcgg ggtcggcgac ctgctggacg gggatggtct gctgcgcctg
    14821 ggcggcacgg gcgatccggg tcgccgggcg cgagcgcagg tagtacgtcg tcttcagccc
    14881 ggacttccag gcgtacgcgt acatcgagga gagcttgccg atcgtcggcg tctccatgaa
    14941 caggttcagg gactgcgcct ggtcgaggaa cggggtgcgc gccgccgcca tgtcgatcag
    15001 accgcgctgc gggatctccc acgcggtgcg gtacagcgcc cgcacctcct cggggatcca
    15061 cgcgaagccc tgcaccgagc cgttggcctc gcgcagcgcc tcccgggtgc gcgcgtccca
    15121 gacgcccagg cccttcaggt cctgcaccag gtaggagttg acctggagga actcaccgga
    15181 cagcgtctcg cgcttgaaca ggttggacac ctgcggctcg atgcactcgt agacgcccgc
    15241 gatggaggcg atggtggccg tcggcgcgat cgccagcagc agcgagttgc gcaggccgac
    15301 ctcggcgatc cgcttccgca gcgccgccca gcgctcgggc caggtctcct cgacgccgta
    15361 gtggtcgggg tgcagcacac cgcgcgcggt ccgggtctgc tcccaggcgg gaagcgggcc
    15421 gctgcgctcg gcgaggtcgg cggacgcctc gtacgcggcg agcatgatcc gctcggcgat
    15481 cttcgtggac agcgccttcg cctcgggcga gtcgaagggc agccgcagct tgaagaagac
    15541 gtcctggagg cccatcgcgc cgaggcccac cgggcgccac ttggcgttgg agcggcccgc
    15601 ctgctcggtc gggtagaagt tgatgtccac gacgcggtcg aggaaggtga cagcggtgtg
    15661 gacggtctcg tccaggcgcg cccagtcgat gtccccgtcg acgacgaagg cacccaggtt
    15721 gacggagccc aggttgcaga ccgccgtctc accgtcgttg gtgacctcca ggatctccgt
    15781 gcagaggttg gaggagtgga tgacctggcc cggctcggcg gtctggttgg cggtgcggtt
    15841 ggcggcgtcc ttgaacgtca tccagccctg gccggtctgc gcgagggtgc gcatcatgcg
    15901 gccgtacagc tcacgggccg gcatggtctt cttcgcgagc cccttgcgct ccgcctcgcg
    15961 gtaggcggcg tcgaactccg cgccgtacag gtccaccagc tcgggcacgt ccgccgggga
    16021 gaacagcgac cactgcccgt cggcgttgac ccggcgcatg aactcgtccg gcacccagtg
    16081 cgcgaggttc agattgtgcg tacggcgggc gtcctcaccg gtgttgtccc gcagctccag
    16141 gaactcctcc aggtcggagt gccaggtctc caggtacacc gcggccgcgc ccttgcgccg
    16201 gccgccctgg ttcaccgcgg ccaccgaggc gtccagggtc ttcaggaacg gcacgatgcc
    16261 gttggagtgc ccgttggtgc cccggatcag cgaaccgcgg gcgcggatac gggagtacga
    16321 cagaccgatg ccgccggcgt gcttggagag ccgggcgacc tggtggtagc ggtcgtagat
    16381 ggagtccagc tcgtccagcg gggagtcgag gaggtagcag gacgacatct gggggtgccg
    16441 ggtgccggag ttgaacaggg tgggggagga gggcaggtag tcgagccggc tcatcagccg
    16501 gtagagcgcg gcgacctcgt ccaccgagcg tgccgagtcg tcctcggcga ggccggcggc
    16561 gacacgcagc atgaagtgct ggggggtctc gatgacctga cgggtgatcg ggtggcgcag
    16621 cagatagcgg ctgtgcaggg tgcgcagccc gaagtagccg aagcggtcgt cggcggcgcg
    16681 gtcgatcagg tggtcgagcc gggcggcgtg gatccggacg aactcggccg tccggtcggc
    16741 gatgagcccc tcgcggtgtc cgacggcgac cgactcggtg aaggacgcca cgccctgcga
    16801 ggcggcctcg gcgcggatgg agatggtcag cagccgggcg gcgagccgcg agtacgcggg
    16861 gtcctcggag atcaggccgg ccgcggcctc ggtcgcgagc tcgcgcagct ccgcctcgtc
    16921 ggcgtgggcg gagcggccgc gcagcgcggc ggcggcgacc cggccgggat cggcgtcggg
    16981 gaggtccccg gtcagctcgg tcagggtccg cagcagcgcg gtaccgggac cgtcgttctc
    17041 caggccctgg gctgaagccg gttcggctgg cgcgatggtc acgtggggct ctccctcgct
    17101 cggcacgggg cctggcggag ggcaggggca gccacgagcg cacacggcgt cgcgtccacc
    17161 ggcccactcc gcgaggcccg gacgtctcag agcacccgaa ccggtgggcc gggtgcgctg
    17221 ccggcaggtc ctcggactga tccccgtgcg cggatgcgca caagtacacc gttgcgggac
    17281 agttccggat tcgcaccgga ttcccctgcg acgacagcga ccatgagcat acatctagtg
    17341 ccgggccgga atgccacccc cagatgttgt gtcaccgtgt gtctacgagg ggtatgcgaa
    17401 acggggcgcg aggggcacgc gaaacgggcc gccggcgccc tttggcgccg ccggcccgcc
    17461 cctggccgcc cgggtccccg ggcgcctcgc tagtggctgg tgcccgccgt ggcgggcggc
    17521 agctcgacct gtacgcccgg gtcgccggcg tccgccgtgt agtcctcggg acgggtctcg
    17581 tcgatgccct cgggggcctt cacggccttc aggacgacgg tcaggacgac cgtgacgagg
    17641 acgttgagga cgaaggccgt catgccgatg taaccgatct ggccgatgcc cgggatgtcg
    17701 tcggcggagc cgccgaagtg cttctgggtc ggggaggcga caccgtacgc ggcgagggtg
    17761 ccgtagatca tgccgaccgc ccagcccgcg agcagcgccc agcggtggaa ccagcgggtg
    17821 aacaggccgc cgaccagggc cgggaaggtc tgcaggatcc agatgccgcc gagcagctgg
    17881 aagttgatgg cgaccgtctt gtccatgccc agtacgaaga tcagcgcgcc gaccttcacc
    17941 agcagcgaca cgaacttgga gacctgcgcc tcctgcttcg gcgtggcgtc cggcttgatg
    18001 aagtccttgt agatgttgcg cgtgaacagg ttcgccgccg cgatcgacat gatcgccgcc
    18061 gggaccagcg cgccgatgcc gatcgccgcg aacgccacac cggcgaacca gtccgggaac
    18121 atgtcctcga acagctgcgg gatcgccagc tgcccgttgg tgaccttcac cccggccgcg
    18181 atcgccatga agcccagcag cgccagcagg cccagcatca gggagtacag cggcaggatg
    18241 gtggtgttgc gccggatcac gttacggctc ttggaggaga gcgtcgcggt gatcgagtgc
    18301 gggtacatga acagcgcgag cgcggaaccg agggccagcg tggcgtacgt ccactgtccg
    18361 gcgggcgccg gcgcgagcgc cccgcggggc ttgccggtgg ccgggttgac ctggctgaac
    18421 gcgtgggccg ccttggcgaa gatgtcgtcg aagccgccca gcttgatcgg gatgtagatg
    18481 atcgccacac cgatcacgat gtagatcagc gcgtccttga cgaacgcgat cagcgcgggc
    18541 gcccgcagcc ccgaggagta cgtgtacgcg gccagcaccg cgaacgcgat cagcagcggc
    18601 aggtccttca cgaacgcgtt ggtgttgtcg ccgccgccga cgcccatcac gtccagcacc
    18661 gcctggatgc cgacgagctg gagcgcgatg tacggcatcg tcgccaggat gccggtcacc
    18721 gcgaccgcga gcgacaggcc cttcgagccg aagcggccgc gcacgaagtc ggaggtggtg
    18781 acgtagccgt ggcggtgcga gaccgaccac agccgcggca ggaaggtgaa gatcagcggg
    18841 tagaccagga tcgtgtacgg caccgcgaag aagccggacg cgcccgccgc gtagatcgcc
    18901 gccggtacgg ccacgaaggt gtacgccgtg tacaggtcgc cgccgagcag gaaccaggtg
    18961 atccaggtgc cgaacgaccg gccgcccaga ccccattcgt ccagcgtgtg ctcgttctcg
    19021 gcccggcgcc agcgcgcggc gaggaagccc aggaccgtga cggccaggaa gaagaagatg
    19081 aagacgccca gtgcgacgcc gttgaccccg gtcttcactt cgcggcaccc ccctgcgcgt
    19141 cacggcggga gcgctggtcg tgctgccaga gcttgtacgc ggtcatggtg agggcggtgg
    19201 agatcagcac ccagaccatc tggtaccagt agaagaaggg gatcccgatg aacgtcgggt
    19261 ccgtcttcgc gtacgagccg acccacagca tcgccacgaa gggcgcgacg agacaaatgc
    19321 cgatgaccac gcgcagcggt gtcaccaccg gtggtcccac ttcgggcgtt tctgacatgc
    19381 tgcggctccg tcccctcgct gatcaccgag taatgcgcag gcaatctagg tgacggtatc
    19441 cagccggtgg aagaccccgt ctcaagctgt gtgtatcgat tcggcgaagg aacggacgcc
    19501 tccgggcggg cctcagtcca tcgggcgctt gaggcgggcc acgaacttgt agcggtcgcc
    19561 gcggtacacc gaccgcaccc actcgaccgg caggcccgcg cggtccagcg agtgccggga
    19621 gagcatcagc atcggcagcc cgacgtccgt gccgagcaga ccggcctcgc gcggggtggc
    19681 cagcgaggtc tcgatggtct cctcggcctc ggcgaggtgg acgtcgtaca cctcggcgag
    19741 cgcggtgtag agggacgtgt acttgaccag cgaacggcgc agcgcgggga agcgcttggc
    19801 ggacagatgg gtggtctcta tggccatggg ctcgccgttg gccatgcgca gccgctcgat
    19861 gcgcagcacc cggccgcccg cggagatgtc gagcagcccg gcgagccggt cgtcggcggt
    19921 gatgtagccg acgtccagca gctgggaggt gggctccagg ccctgggcgc gcatgtcctc
    19981 ggtgtaggag gtgagctgga gcgcctggga gaccttgggc ttggcgacga aggtgccctt
    20041 gccctggatg cgctccaggc ggccctccac gaccagctcc tgaagggcct ggcggacggt
    20101 ggtgcgggag gtgtcgaact ccgcggccag cgtgcgctcc ggcgggaccg gcgtgccggg
    20161 cgcctgcgtc tccgtcatgt cgagcaggtg cttcttcagg cggtagtact tcggcacgcg
    20221 cgcggtacgg acggtggtgc cggcctcgtt ctccgcactg ctgacatcgg tgctcatgct
    20281 ccgccttccc ggctccggac gccgaaagcg accgacatcc catcggccac ggctcacatc
    20341 gtggcacggc ttaccgtgcc aggactccac ccgcacgctc cgtgatcccc tctgtatacc
    20401 gtcgggaccc gagctggtct agtccaacag gggtcccatg ggcaccgggt gcggtcctgc
    20461 tagatcccct gccactccgg cttgttcgcg taggtgtgcc ggaagtagtc cgccagcttc
    20521 agctcggcgg cggccgcctc gtccacgacg acggtggcgt gcggatgcag ctggagcgcg
    20581 gaggccgggc atacggccgc caccggaccc tcgacggtcg ccgcgaccgc gtccgccttg
    20641 ccctcgccgg tcgcgagcag caccaggtgc cgggcctcca ggatggtgcc gatgccctgg
    20701 gtgatgacgt ggtgcgggac ctgctcgatc tcgccgtcga agaagccgcg ttgtccacgc
    20761 gggtctgctc ggtcagggtc ttgatccggg tgcgggaggc gagcgaggag cagggctcgt
    20821 tgaacccgat gtgcccgtcg gtgccgatcc cgagcagctg gaggtccacc ccgccggccg
    20881 cggcgagcgc gcggtcgtac gcctcgcacg ccgcctggac gtccttcgcc gtgccgtcgg
    20941 ggccgaggaa ggagtccatg ccgatgccga gcggctccag cacctcgcgg cgcagtaccg
    21001 agcggtagga ctcggggtgc tcggcgggca gccccacgta ctcgtcgagc tgggctatcc
    21061 gggcccgcgc ggtgtccacg tcaccg
//
