LOCUS       NZ_CP047146            21059 bp    DNA     linear   CON 30-JAN-2024
DEFINITION  Streptomyces sp. GS7 chromosome, complete genome.
ACCESSION   NZ_CP047146
VERSION     NZ_CP047146.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. GS7
  ORGANISM  Streptomyces sp. GS7
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9067183)
  AUTHORS   Li,J., Ni,J. and Li,Y.
  TITLE     Multiple polyene macrolides produced by antifungal Streptomyces from
            gut of Macrotermes barneyi facilitates the termite-fungus mutualism
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9067183)
  AUTHORS   Li,J., Ni,J. and Li,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-DEC-2019) State Key Laboratory of Microbial
            Technology, Shandong Unversity, 72 Binhai Road, Qingdao, Shandong
            266237, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 20-NOV-2019
            Assembly Method                   :: SPAdes v. Nov-2019
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/30/2024 05:53:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,019
            CDSs (total)                      :: 7,925
            Genes (coding)                    :: 7,616
            CDSs (with protein)               :: 7,616
            Genes (RNA)                       :: 94
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 309
            CDSs (without protein)            :: 309
            Pseudo Genes (ambiguous residues) :: 0 of 309
            Pseudo Genes (frameshifted)       :: 107 of 309
            Pseudo Genes (incomplete)         :: 258 of 309
            Pseudo Genes (internal stop)      :: 29 of 309
            Pseudo Genes (multiple problems)  :: 79 of 309
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:40:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4981451
            Orig. end                         :: 5002510
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP047146.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Jinfeng Ni.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21059
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="19"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21059
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21059
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11059](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11059
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(925..939)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     gene            1109..2149
                     /locus_tag="GR130_RS22030"
                     /old_locus_tag="GR130_22030"
     CDS             1109..2149
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1113:
                     inner-membrane translocator"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018538067.1"
                     /locus_tag="GR130_RS22030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_22030"
                     /product="ABC transporter permease"
                     /protein_id="WP_159506294.1"
                     /transl_table=11
                     /translation="MTHSPRRPPGSRFGHLTGAYGLLALGALLFLAFSLALPDTFPTLD
                     NISEVLSNQSIPAILALGATIPIVTAKFDLSIGYGLGLAHVMTMQLIAHEAWPWPLACL
                     LVVLGGTLVGILNGAVVEFARINSFIATLGTGSILYAVTGWITNGARIVPGPHGLPTAF
                     TDLYDSRFLGLPVSAFYVLALTAVLWLVLERLPLGRYLYVIGSNPRAAELVGIPTRRYV
                     IHAFAGSGLVVGIAGVLLAAQQRIGNPSVGLDYLLPAFVGALLGSTAIRPGRANALGTL
                     VAVVVLAVGLAGIGQLGAQFWVTPLFNGATLLLAVGMAGYAARRQLRRQRTEPPRTLPD
                     PPRTTP"
     gene            2212..3339
                     /locus_tag="GR130_RS22035"
                     /old_locus_tag="GR130_22035"
     CDS             2212..3339
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018538066.1"
                     /locus_tag="GR130_RS22035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_22035"
                     /product="substrate-binding domain-containing protein"
                     /protein_id="WP_159510134.1"
                     /transl_table=11
                     /translation="MTVAAAVLTAGTALLGCERGTSVGGGPLPPSPAKPGCPTVLARAA
                     AAVQQAEKTNPATTGPTSGPRATTGKTVVYVAQTMTNPGVAGAANGVAEAARTIGWDLR
                     VIDGRGTPAGIQAAFGQAITLRPSGIVIGGFDPDLTSQQVAQATAERIPLVGWHAVGSP
                     GPSRHPALFTNITTRVEDVARTSAEWIIAHSHGHAGVVLFTDASIPFARTKSELIRKEL
                     ASCSGVKLLAEDNIPISDSSSRTPQEVSALLSRFRDAWTHSAAINDVYFADAAPALRAA
                     RKKGAAAPFNIGAGDGDPSAFQRVNSRQFQAATVPEPFAQQGWQILDEFNRAFSGRPAS
                     GYVAPVHIATAANSAGATTWDPPGYRAAYRKIWGR"
     gene            3624..4154
                     /locus_tag="GR130_RS22040"
                     /old_locus_tag="GR130_22040"
     CDS             3624..4154
                     /GO_function="GO:0032559 - adenyl ribonucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016571117.1"
                     /locus_tag="GR130_RS22040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_22040"
                     /product="universal stress protein"
                     /protein_id="WP_159506295.1"
                     /transl_table=11
                     /translation="MNKPGYRVVAGVSGSLESLTALHRAASEARATGATLWAVLAWEPP
                     GGDIAHRGGPCPEPLAAWRRMAVDRLTDALGTAFGGTGPGVPLERLVVLGKPAKVLLSV
                     ADRPDDLLVVGAGARGRMRRALQPSVARYCLARAGCPVLAVPPSPLHRTFHTMHRRNTW
                     KLPLKTQGLAERR"
     gene            complement(4320..5279)
                     /locus_tag="GR130_RS22045"
                     /old_locus_tag="GR130_22045"
     CDS             complement(4320..5279)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016573655.1"
                     /locus_tag="GR130_RS22045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_22045"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_159506296.1"
                     /transl_table=11
                     /translation="MRHTLDETDRRIAASLLASPRASWREVARCLGLSERTVVRRAAPL
                     YADGTLRTTAVRNPACFPHLIPIALRIRCRPNKIRQVAHALARRTDTVWVDILGGGDEI
                     STVFFLDGPDARNALLLRDLPATEAVDSWTAHTLLRVFPTAFRWTAGLLSPQEVAQLIP
                     DPTPPTAPALPLAVDTALIAALTEDGRTTYTELARRAGTTALAARRRLDALVRGQAVRL
                     ATEVDLALLGAHTEALLWIAVRPGALGEAARTLSVHPHVRFCAATTGPANLVVALATAD
                     LDTLYAFLTDAVGLLDGITAIDTTPLLATVKRTGLIRH"
     misc_feature    complement(5278..5291)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.92"
                     /tool="antismash"
     gene            5474..7093
                     /locus_tag="GR130_RS22050"
                     /old_locus_tag="GR130_22050"
     CDS             5474..7093
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016573656.1"
                     /locus_tag="GR130_RS22050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_22050"
                     /product="amidohydrolase"
                     /protein_id="WP_159506297.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 2.7e-09, bitscore:
                     35.5, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDHGADLVIRAGAVHTLVPGQAPRRALAVRGDRIMALSPDPNGL
                     DHLVSARTTVHDLPGATVLPAFDDTHTHLIFAAHGAHDVPVHRARTIPEFLGLIRQRAR
                     TTPEGEWIRTTTNWQELNLAERRMPTAAELDQATDRHPVLVKRGGHNDVVNTYALRLAG
                     VTEDTPVPPGGVIGRDADGSLNGRLIDNALPLVERLVPAQDRARRIDALHLASGWYAAT
                     GIGTVRDCAVSPEDYAVLLAAREAGALSIRVRALVSALGMTGRAQVEDLLDVMEDWRYN
                     SDPRLGVWGVKFGLDGGLEAGATEEPYACDHAFSGMLTWEPDALVEAVEAVVRRGWRVG
                     THSYGDRAVRILLDVYERVLDRNPGLPAGTLVMEHGGLAGPGQRARAAALGIPVTIQQP
                     LLHDTAEVEEGFWGPERVARLFPARGWLDQGAQVSAGSDFPVGQFGAMRSVWGMTTRQT
                     VIGVKGAEHAITYDEALALHTTNAARLCGEENLRGTLTPGRLADLSVWDQDPAHCAGET
                     LRDLSASHTFVGGLLVSSTTAQ"
     gene            7205..8194
                     /locus_tag="GR130_RS22055"
                     /old_locus_tag="GR130_22055"
     CDS             7205..8194
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024880.4"
                     /locus_tag="GR130_RS22055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_22055"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_236573349.1"
                     /transl_table=11
                     /translation="MRIEVLVVPDCPHEKAAVELLRHALDDAGLTDVTWDRRVVADQDA
                     AERIGFAGSPTFLIDGRDPFAEPGRAPGLTCRMYPTPQGPAGLPTRDRLRQALTSACPA
                     GGAPAGAGGEAQQAREQRRHWQDTYAAHPGMYGAEPSAPAVHAAGVFRAAGAERVLELG
                     AGHGRDALYFAREGFAVHATDFSSTGLDQLREASRAQGLADRIATTVHDVRSPLPFPDD
                     SVDAVFAHMLLCMALTTREIHALVAEVRRVLRPGGVFVYTVRHTGDAHYAAGTSRGDDI
                     YEHGGFAVHFFPRRLVDGLAGGWRLDEVHGFEEGELPRRLWRITQTLA"
     gene            8542..9981
                     /locus_tag="GR130_RS22060"
                     /old_locus_tag="GR130_22060"
     CDS             8542..9981
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016576907.1"
                     /locus_tag="GR130_RS22060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_22060"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_159506298.1"
                     /transl_table=11
                     /translation="MSTPDSVTGSATEEPALDPADTALTSLSTQAARQLATTTKSVPQM
                     QAITSRWLLKALPWVDVKGGTYRVNRRLQLRVGRGRVQFEQNGADDIKVIPQTLTELPV
                     LRGYPDIDVLKEVAGRFRVREVRAGQVLFEAGQPATEAYLVVHGRFARYAAGKYGEEEV
                     IGVVTDGDQMGDEAIGLAEPRWQTSVRAQTAGVLLVLPWDVVQEFTDRVPSLAAHLAAY
                     AEQQQRPVNRKGEAEVPVAAGHVGEPTLSGGFVDYDLTPREYELSLTQTVLRVHSRVAD
                     LYNEPMDQTQQQLRLTVEEIRERQEWELVNNREFGLLHNTDYGQRISTYSGPPTPDDMD
                     ELLSMRRKTRLFLAHPKAIAAFFRQCNKRGLVPGTANVDGHEVPAWRGVPIFPCGKIPV
                     SGEHTSSIIALRTGEADQGVVGLHQTGLPEEFQPGLNVRFMGIDNAAIIKYLVTAYYSM
                     AILVPDAAGILENVQIGRSAD"
     gene            10001..11059
                     /locus_tag="GR130_RS22065"
                     /old_locus_tag="GR130_22065"
     CDS             10001..11059
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018538318.1"
                     /locus_tag="GR130_RS22065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_22065"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_159506299.1"
                     /sec_met_domain="T1TS (E-value: 5.1e-48, bitscore: 163.4,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTPPDTAAGYSLPGPPNLARTLRARRGGAVPGLKYRPAVPADPE
                     KAGEIDRRLESWARRLDLFPAQWTGDFAQFQVGRAVVLQHPGAADLERLTVAGEFLLAE
                     NIVDSCYCEEDEGRGASRRSLGGRLILGQSALDPFHGTPALEEEWRRGMQADGPLRSYH
                     WAMQDYAAFATPSQTGRFVHDMARLHLGYLAEASWSQTRHMPHVWEYLVMRQFNNFRPC
                     LSLVDAVDGYELPEALYARPEVQRVTALACNATTIVNDLYSFTKELASDPNHLNLPQVV
                     AANDKRGLKAAYLKSVEIHNEVFEAFEAESAPLAAASPLLERYVRGLSAWVAGNHEWHA
                     TNTDRYHLPNYW"
     gene            11093..11968
                     /locus_tag="GR130_RS22070"
                     /old_locus_tag="GR130_22070"
     CDS             11093..11968
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016574303.1"
                     /locus_tag="GR130_RS22070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_22070"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_159506300.1"
                     /transl_table=11
                     /translation="MTIAHADTVRTPVPTQSTYQSRVADYWNAEENPVNLELGKIDDLY
                     HHHYGIGDADWSVLDEPDPDLRREQVTGELHRLEHAQAELLASHLGDLSPTDRVFDAGC
                     GRGGGSVVAHLRYGCHADGATISAKQADFANEQARKRGIDDKVRYHHRNMLDTGFTSGA
                     YAASWNNESTMYVELELLFAEHARLLRRGGRYVTITGCYNDAYGRASREVSLINAHYIC
                     DIHPRSAYFNAMAHNRLVPVHVQDLTEAALPYWELRRQADHLVTGIEETFLNAYRNGSF
                     QYLLIAAERV"
     gene            12074..12499
                     /locus_tag="GR130_RS22075"
                     /old_locus_tag="GR130_22075"
     CDS             12074..12499
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004986724.1"
                     /locus_tag="GR130_RS22075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_22075"
                     /product="pyridoxamine 5'-phosphate oxidase family protein"
                     /protein_id="WP_159506301.1"
                     /transl_table=11
                     /translation="MTLSMRERELFLAEPHIGALSVIERPDRAPLTVPIWYQYTPGGEL
                     WVRTGPDSRKARAIRSAGRFSLMVQRTEPTVRYVSVEGPVTRTEPDSRERSWEMAARYL
                     PQDKVADFVEYDRTRLGEHIAVYMRPEHWLSADMGSL"
     misc_feature    complement(12096..12107)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.74"
                     /tool="antismash"
     gene            12748..13200
                     /locus_tag="GR130_RS39965"
     CDS             12748..13200
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GR130_RS39965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_201304964.1"
                     /transl_table=11
                     /translation="MKLAIRTGLVVAIAASAFAALAPTAGAATARSDQAANEPNWATTS
                     AVAPVAAGDHAMGARLAANPTTIKAAAYNQARSILAKAGSDSAAKSHPVHGTGDVPVRY
                     GTSLLAGSRDEFRSKDRNVPDKKSGMSPAHYQAIHDAARTMGIDRW"
     misc_feature    12754..12756
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(13384..13770)
                     /locus_tag="GR130_RS22085"
                     /old_locus_tag="GR130_22085"
     CDS             complement(13384..13770)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016906415.1"
                     /locus_tag="GR130_RS22085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_22085"
                     /product="VOC family protein"
                     /protein_id="WP_159506302.1"
                     /transl_table=11
                     /translation="MLDHIAIQVRDLAASAAFYDAVLAPLGGERRKQFGENIGFGVTGH
                     PLWLVPATDPAPARELHIAFAAADRAAVDGFYAAALAVGAEVLHAPRLWPDYHESYYGA
                     FVRDPDGNNVEAVCHRPDGLGGSR"
     misc_feature    complement(13693..13695)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    13754..13770
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.34"
                     /tool="antismash"
     gene            complement(13964..14410)
                     /locus_tag="GR130_RS22090"
                     /old_locus_tag="GR130_22090"
     CDS             complement(13964..14410)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003976571.1"
                     /locus_tag="GR130_RS22090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_22090"
                     /product="DUF1772 domain-containing protein"
                     /protein_id="WP_159506303.1"
                     /transl_table=11
                     /translation="MLNALEVFTTVVLGLMVGVEFSVLFVLNPILNALPEDSGQLGHAH
                     GGRMLGAVMPVWYITSLVLVAVWAIAGWHHHGTGLVVTAGALLILSVIMSLLLLVPINN
                     RNKTWTPENRPEDWKEQMNRWARYHYVRVAVIIAAFALLVAALT"
     gene            14502..15080
                     /locus_tag="GR130_RS22095"
                     /old_locus_tag="GR130_22095"
     CDS             14502..15080
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981641.1"
                     /locus_tag="GR130_RS22095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_22095"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_159506304.1"
                     /transl_table=11
                     /translation="MSVQERKQRERAERERLIVATARELAEQQGWDAVTTRRLAERIEY
                     SQPVLYSHFRGKREIIGAVALQGATEMAAAVRAAASRANSPRERVAALARTYLDFAARN
                     PAVYDAIFQLDGGLAFAHEDTPEPLKDAFAALLESLGEVTGDGVHPGLFTEVFWAALHG
                     LATLTRARRLPPEDTERRVELLVDRLAVV"
     misc_feature    14508..14519
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     gene            complement(15341..15811)
                     /locus_tag="GR130_RS22100"
                     /old_locus_tag="GR130_22100"
     CDS             complement(15341..15811)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015655545.1"
                     /locus_tag="GR130_RS22100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_22100"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_159506305.1"
                     /transl_table=11
                     /translation="MTGAGAARVRRARAADLPQVVHLVADHAAYEKAPPPPTDLARRLE
                     VLLFSTETPRLRCFVAELNDGEIIGYASCAPEISTWDGAEYLHMDCLFLRDGHRGLKVG
                     SLLVEAVVAEAHALGLGQVQWQTPPWNTDAIRFYNRLGAQAKEKLRYQLPVS"
     gene            complement(15808..16341)
                     /locus_tag="GR130_RS22105"
                     /old_locus_tag="GR130_22105"
     CDS             complement(15808..16341)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007379709.1"
                     /locus_tag="GR130_RS22105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_22105"
                     /product="hypothetical protein"
                     /protein_id="WP_159506306.1"
                     /transl_table=11
                     /translation="MRDLAESQLGESLAAVDSDALLALADDYHARAVRPLGSRAVAGHL
                     VKSYAIEAPGRSVTDQDVQNAVRIAADYLSSAQSRGSLGLSVLLIHAGGDGDYILVHTW
                     IEGYMSDLAIFTGPAGDATQLRPGRVGLAPCVWEAAVLAHERDALTRHVLDSHGAVAER
                     LVAWRGDVLEGEVR"
     misc_feature    complement(16446..16459)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 22.87"
                     /tool="antismash"
     gene            complement(16504..17049)
                     /locus_tag="GR130_RS22110"
                     /old_locus_tag="GR130_22110"
     CDS             complement(16504..17049)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018538098.1"
                     /locus_tag="GR130_RS22110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_22110"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_159506307.1"
                     /transl_table=11
                     /translation="MDKLDLLLHPVRLRIVHAMSGGRTRTTSDLCASLPDVPKTTVYRH
                     VGLLADAGVLEVTDEQRVHGAVERHYRLRRERAVIDADEAAAMSRDDHRQGFTAALAGL
                     HADFNAYLDRDDTDPIADSVGYTQIPLWLDRDELAELIDELLSAIRSKRHNKPAPGRSL
                     HLLSPILFPLERLPHQDG"
     gene            17238..17372
                     /locus_tag="GR130_RS41390"
     CDS             17238..17372
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GR130_RS41390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_268977931.1"
                     /transl_table=11
                     /translation="MRAAHEQVADRARGFGVHGTLHALFVSEASGRIAKVPVPGRGTD"
     gene            complement(17510..18397)
                     /locus_tag="GR130_RS22115"
                     /old_locus_tag="GR130_22115"
     CDS             complement(17510..18397)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016575668.1"
                     /locus_tag="GR130_RS22115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_22115"
                     /product="DUF4190 domain-containing protein"
                     /protein_id="WP_159506308.1"
                     /transl_table=11
                     /translation="MTTPVSPDGPTTGDPLPRHRDPWAAPPAESDAYRAPCPPPAWTPQ
                     PSNGMGITALVLALVGLVLGAFIFLFWLSWLPALLAVIFGGIGLSRVRTGRATNKAMAF
                     SGVVLGILGLVAAAGGAAFTVVLVKGVVDRDRAHVKEVDADARAKAEAARESAAAAEKA
                     RHLSFGKSYTFGDGLKVTVGKPVPFSPDGYVLGHAKGNKAVQVTVAVVNTGGRRVAVET
                     GLPSVNDADGASTELVIDGSGRQKVLTGYVLPGKEAVGKYAFSLPPGAADRIEVEFSPD
                     AKRWEDAYWSGPTT"
     misc_feature    complement(18426..18440)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.65"
                     /tool="antismash"
     gene            complement(18606..18827)
                     /locus_tag="GR130_RS22120"
                     /old_locus_tag="GR130_22120"
     CDS             complement(18606..18827)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019349.4"
                     /locus_tag="GR130_RS22120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_22120"
                     /product="FCD domain-containing protein"
                     /protein_id="WP_268977932.1"
                     /transl_table=11
                     /translation="MEPIAAAIYLRWSGPVGQDYDRDVAREHQALLDAVLARDPRAAAD
                     LLAQHIDRTSASLRAVIQGKAEPVRVRP"
     gene            18865..19293
                     /locus_tag="GR130_RS22125"
                     /old_locus_tag="GR130_22125"
     CDS             18865..19293
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012335.4"
                     /locus_tag="GR130_RS22125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_22125"
                     /product="hypothetical protein"
                     /protein_id="WP_328707597.1"
                     /transl_table=11
                     /translation="MGYDAEVLRKAGPIDEQPRAAAPDGLDVVVDNVGGEQPKAAIGLA
                     RRGARIALIGTLAGQLGDSATTEIDPHALIAGSIALRGAALYDYLDIIPEWTDFFARAL
                     RDGTLTFPRTVLTGLDQAPRALRELVEGRHLGAVHMEL"
     gene            19543..20187
                     /locus_tag="GR130_RS22130"
                     /old_locus_tag="GR130_22130"
     CDS             19543..20187
                     /GO_function="GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014818415.1"
                     /locus_tag="GR130_RS22130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_22130"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_159506309.1"
                     /transl_table=11
                     /translation="MDQLLRIMNFNVSRDGIGAGEHQSLQRPFGHDHPERLFAWAGATA
                     SWPMRTDPGGSRGLDDYFTRDFTRNIGAEIMGRNKFGPQRGPWQDHEWRGWWGEEPPFH
                     TPVFVMTHHQRPSFTLCDTTFHFVDGSPATILERAREAAQGKDVRLGGGVTIIRQFLDA
                     DLVDTMHVAVSPVKLGSGLRLWESPDELLDRFHLEVVPSPSGVTHHLFWRR"
     misc_feature    19554..19569
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.7"
                     /tool="antismash"
     gene            complement(20497..20751)
                     /locus_tag="GR130_RS22135"
                     /old_locus_tag="GR130_22135"
     CDS             complement(20497..20751)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GR130_RS22135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GR130_22135"
                     /product="hypothetical protein"
                     /protein_id="WP_159506310.1"
                     /transl_table=11
                     /translation="MLAVVLALANQMLHAHAVLMATGSITLFLVVFATGTLLMLHGGAV
                     GKSPQAPAAGDRPASSSRRTRYRRQLRLRPHRPESHRSG"
ORIGIN
        1 acctcgaccc gcgcgccacc ctcgccggcc tgccgcgagc cgaacgctcc ctggtagcca
       61 tcgcccgcgc gctgtccaca cgggccgaac tcatcgtcct cgacgagccg accgccagtc
      121 ttccggccgc cgactgcgcc cggctcttcg gcgtcctgca caccctgcgc gaccagggcc
      181 gcgccatcgt ctacgtcacc caccggctcg acgaggtcta ccaggtcgcc gacgccttcg
      241 ccgtcctgcg cgacggccgc ctcatcagcc agggcccgct cgccgaccgc agccccgccc
      301 gactggtccg cgacatcgtg ggccacgaac ccggccggta ccggcccgcc cccgccgcgg
      361 gccgccccgt cctgtgtctg gaccgcgtac ggaccggcaa cacggcaccg gtcagcctgg
      421 aactgcacgc cggcgagatc ctcgggatgg tggggctcac cggcgccgga cacctggaac
      481 tgggccgcgc cctcgccggt gcccggcccc tcctcggtgg acgggccctg ctcgacggac
      541 ggccatacgc accgcgcacg gtggccgccg cggtcgcctc cggcgtcggc ctggtgaccg
      601 gcaaccgtca ggaggagggc tgcgccgccg aactgaccgt acgggagaac atcctggcca
      661 acccccgggc cgacggcctc ccggccctcc actggatcag cccccggcgc gagcgggcca
      721 aggccaccgc cctgatcgac cgggtcgcgg tgcgcccgcg ggacagcgaa gcacctctct
      781 ccgccctgtc cgggggcaac cagcagaagg tcatggtcgg ccggtggctc cggatcagcc
      841 gcaagctgct gatcctcgaa gagccgaccg ccggggtgga cgtcggcgcc aagtcggcga
      901 tctaccgcat gctccaggac gcgctggccg acggcctcgc cgtcctgctc ctctccaccg
      961 acttcgagga ggtcgccaac gtgtgccacc gtgccctggt attcgtccgc ggggcggtga
     1021 cgacggagct gagcggcgag gccctcaccg tcgccgggct cgcccgcgcc tcctcggcca
     1081 tgcccgcact caccgggacg acggggccat gacccactct ccacgtcgcc caccaggcag
     1141 ccggttcggg cacctcaccg gcgcgtacgg cctcctggcc ctgggcgccc tgctgttcct
     1201 ggcgttctcc ctcgccctgc cggacacctt tcccaccctg gacaacatct ccgaggtcct
     1261 gtccaaccag tcgatccccg ccatcctcgc gctcggcgcg acgatcccca tcgtcaccgc
     1321 caagttcgac ctgtccatcg gctacggcct cggcctcgcg cacgtcatga ccatgcagct
     1381 catcgcccac gaagcctggc cctggccgct cgcctgcctc ctggtggtcc tcggcgggac
     1441 actggtcggc atcctcaacg gcgcggtcgt cgaattcgcg cggatcaact ccttcatcgc
     1501 cacgctcggc accggcagca tcctgtacgc cgtcaccggc tggatcacca acggtgcccg
     1561 gatcgtcccc ggcccgcacg gcctgcccac cgccttcacc gacctctacg actccaggtt
     1621 cctcggcctg ccggtatccg ccttctacgt cctcgcactc accgccgtcc tctggctggt
     1681 cctggaacga ctgcccctcg gccggtacct gtacgtcatc ggctccaacc cccgcgccgc
     1741 cgagctggtg ggcatcccca cccggcgcta cgtcatccac gccttcgccg gatcgggcct
     1801 ggtcgtcggc atcgcgggtg tcctgctcgc cgcccagcag cgcatcggca accccagcgt
     1861 cggcctggac tacctgctgc ccgccttcgt cggcgcactg ctcggctcca ccgccatcag
     1921 acccggccgg gcgaacgccc tgggcaccct ggtcgccgtc gtcgtcctcg cggtcggcct
     1981 ggccggcatc ggtcagctcg gcgcacagtt ctgggtcacc ccgctgttca acggcgccac
     2041 cctgctcctc gccgtcggca tggccggcta cgccgcccgc cggcagctgc gccgacaacg
     2101 gaccgaacct ccccgcactc tccccgaccc gccccggacc accccatgac ctccgcccgc
     2161 catcaccacg ccatcccgtt gcgcggcacc cgcgcccccg gggcggtcgt gatgacggtg
     2221 gcggctgccg tcctcaccgc cggtacggcc ctcctcggct gcgagcgcgg tacgtcggtc
     2281 ggcggcggcc ctttgccgcc gagccccgcg aagcccggct gccccaccgt cctggcccgc
     2341 gccgcggcgg ccgttcagca ggccgagaag accaacccgg cgacgaccgg ccccaccagc
     2401 ggccccaggg cgaccaccgg caaaaccgtc gtctatgtcg cacagaccat gaccaacccc
     2461 ggcgtcgccg gcgccgccaa cggcgttgcg gaagccgccc ggaccatcgg ctgggacctg
     2521 cgggtgatcg acggccgggg cacccccgcc gggatccagg cggcgttcgg tcaggccatc
     2581 accctgcggc cctcgggcat cgtcatcggc ggcttcgacc ccgacctcac gtcgcaacag
     2641 gtcgcgcagg ccaccgccga acgcatcccg ctcgtcggct ggcacgcggt cggctccccc
     2701 ggcccgagca ggcaccccgc gctcttcacc aacatcacca ccagggtcga ggacgtcgcg
     2761 aggaccagcg cggaatggat catcgcgcac tcccacggcc acgccggtgt cgtcctgttc
     2821 accgacgcct cgatcccctt cgccagaacc aagtccgaac tgatcaggaa ggaactggcc
     2881 tcctgctccg gcgtcaagct gctggcggag gacaacatcc cgatctcgga ctccagcagc
     2941 cgaactcccc aggaggtctc cgcacttctc tcccgattcc gggacgcctg gacccactcc
     3001 gccgccatca acgacgtgta cttcgccgac gccgccccgg ccctgcgcgc cgcacgcaag
     3061 aagggtgccg ccgccccgtt caacatcggc gcgggcgacg gcgacccttc cgccttccaa
     3121 cgcgtcaaca gcaggcagtt ccaggcggcc accgttcccg agccgttcgc ccagcagggc
     3181 tggcagatcc tcgacgagtt caaccgcgcc ttctccggcc ggcccgccag cggatacgtc
     3241 gcccccgtgc acatcgccac ggccgccaac agcgccgggg ccacgacctg ggacccgccc
     3301 ggctaccgcg ccgcgtaccg caagatctgg ggccggtagg cgggtacgcc cgggaaaccg
     3361 cgcgctgtcc gcgtcgaggt gagtgaccgt caccgccgag gaacgcaccg agtggccctg
     3421 cccggccgga ccgcgccacc acccgctccg cccgtacccg tgtgtcggca ggctgccccg
     3481 catcggattc cggcccgatg gcgtcaggaa cccgtcaagg caacccctcc cggcgcaaag
     3541 aaaacaccaa cacctcgcga tcgcgctatc gggtcgattt ccatggggcg tgtgaacgtg
     3601 gcacagggcg aggagcagac cccatgaaca agccgggcta ccgcgttgtg gccggggtga
     3661 gcggttcgct ggaaagtctg accgcgctgc accgggccgc ctccgaagcg cgcgccaccg
     3721 gcgccacact gtgggccgtg ctggcctggg aaccaccggg cggcgacatc gcccatcgcg
     3781 gcggcccctg ccctgagccg ctggccgcgt ggcgccgcat ggcagtcgac cgtctcaccg
     3841 acgcgctcgg caccgcattc ggcggcaccg gacccggggt accactggag cggctggtgg
     3901 tactcggcaa accggccaag gtcctgctgt cggtcgccga tcggcccgat gacctgctgg
     3961 tggtcggagc cggagcccgc ggccggatgc gccgggcgct gcagccctcc gtggcccgct
     4021 actgcctcgc acgcgccggc tgcccggtcc tcgccgtccc gccctccccc ctccaccgca
     4081 cattccacac catgcaccgc cgcaacacgt ggaaactccc cctcaaaacc caggggttgg
     4141 ccgagcggcg ctgacaccgc gatcgaacgc accgggctac gacgcacgcg gcaggcgtgc
     4201 acgaaacctc gcggacgtcg tggagcagcc acggaggaag gggcgccggc ggcgaggaag
     4261 gcgtcccact cctcgttcgg cggggttcgg aatccctcgt tgggcggagt gaggtctcgt
     4321 cagtggcgga tcaggccggt gcgtttgact gtcgccagca gcggagtggt gtcgatggcc
     4381 gtgatcccgt cgaggaggcc gacggcgtcg gtgaggaagg cgtacagggt gtcgaggtcc
     4441 gccgtggcca gagcgacgac gaggttggcc gggccagtgg tggcggcgca gaagcggacg
     4501 tgcgggtgga cgctgagggt ccgggcggcc tccccgagcg cgccgggccg gaccgcgatc
     4561 cacagcaggg cttcggtgtg cgcgccgagc agggcgaggt cgacctcggt cgccaggcgc
     4621 acggcctggc cgcgaaccag cgcgtcgagt cgtcggcggg cggcgagcgc ggtggtgccg
     4681 gcccggcggg cgagttcggt gtaggtggtc cggccgtcct cggtcagcgc cgcgatcagc
     4741 gcggtgtcca cggccagagg caaagcaggc gccgtcgggg gtgtggggtc ggggatgagc
     4801 tgggccacct cttggggtga gaggagaccc gcggtccagc ggaacgcggt gggaaagacg
     4861 cggagcagtg tgtgagcggt ccaggagtcg acggcttcgg tggcgggcag gtcacgcagc
     4921 agcagggcgt tgcgggcgtc ggggccgtcg aggaagaaga ccgtggagat ctcgtcgccg
     4981 ccgccgagga tgtcgaccca gaccgtgtcg gtgcggcgtg ccagtgcgtg ggcgacctga
     5041 cggatcttgt tcgggcgaca gcggatgcgc agggcgatgg ggatcaggtg cgggaagcac
     5101 gccgggttgc ggacggccgt cgtgcgcagg gtgccgtcgg cgtagagggg tgcggcgcgg
     5161 cgtacgacgg tgcgctcgga caggcccagg cagcgtgcca cctcgcgcca ggaggcacgt
     5221 ggcgaggcga ggagggaagc cgcgatccgg cggtccgtct cgtcgagcgt gtggcgcatg
     5281 atctgcatca taggtcgctg ctgtggcgta tttcctgtgt catgggctgc tgaatgttca
     5341 tgtatcggct ggccgcgcgt acatctgtct ggtcagcgga cgtggccggc gaccggactg
     5401 ctgagcacgg tcgcggcaac tagtggcgcc cctgacacgg tccgaacgac gtcgagacag
     5461 cctggagaag acgatgaccg atcacggagc cgacctggtg atccgggccg gtgcggtgca
     5521 cacgctggtg cccggtcagg ccccgcggcg ggcgctggcc gtgcggggtg accgcatcat
     5581 ggccctctcc cccgacccga acggcctcga ccacctggtg agcgcgcgca ccacggtcca
     5641 cgacctgccc ggagccacgg tgctgcccgc gttcgacgac acccacaccc acctgatctt
     5701 cgccgcccac ggtgcgcacg acgtgcccgt gcaccgggcg cgcaccatcc ccgaattcct
     5761 gggcctgatc cggcaacggg ccaggaccac ccccgagggc gagtggatcc gtaccaccac
     5821 caactggcag gaactcaacc tggccgaacg gcggatgccc accgcggcgg aactcgacca
     5881 ggccacggac cggcacccgg tcctggtcaa gcgcggcggc cacaacgacg tcgtcaacac
     5941 ctacgcgctg cgcctggcgg gggtcaccga ggacaccccg gtaccgccgg gcggtgtcat
     6001 cggccgcgac gccgacggca gcctcaacgg tcggctcatc gacaacgccc tgccgctggt
     6061 ggagcggctg gtcccggccc aggaccgggc ccggcgcatc gacgcactgc acctggccag
     6121 cggctggtat gccgccaccg gcatcggcac cgtgcgcgac tgcgcggtct ccccggagga
     6181 ctatgcggtg ctcctggctg cccgcgaggc gggggcgctg agcatccggg tgcgggccct
     6241 ggtctcggca ctcggcatga ccggcagggc gcaggtggag gacctgctcg acgtcatgga
     6301 ggactggcgc tacaactccg atccccgact cggggtgtgg ggagtgaagt tcggcctcga
     6361 cggcggcctg gaggccgggg ccaccgagga gccgtacgcc tgcgaccacg ccttctccgg
     6421 aatgctgacc tgggagcccg acgcactggt cgaggcggtc gaggccgtgg tgcggcgtgg
     6481 ctggcgggtc ggcacccact cctacggcga ccgcgcggtc cgcatcctcc tggacgtcta
     6541 cgaacgcgtc ctcgaccgca accccgggct gcctgccggc acgctggtga tggagcacgg
     6601 cggcctggcc ggccccggac agcgtgcccg agccgcggcc ctgggcatcc ccgtcaccat
     6661 ccagcagccg ctgctgcacg acaccgccga ggtggaggag ggcttctggg gaccggaacg
     6721 cgtcgcccgg ctcttccccg ccaggggctg gctcgaccag ggtgcccagg tcagcgctgg
     6781 atcggacttc cccgtcggcc agttcggcgc catgcgctcc gtctggggca tgaccacccg
     6841 gcagaccgtc atcggcgtca agggcgccga gcacgccatc acctacgacg aggccctcgc
     6901 cctgcacacc accaacgccg cccgcctgtg tggagaggag aacctgcgcg gcaccctcac
     6961 ccccggccgc ctggccgacc tcagcgtctg ggaccaggac cccgcacact gcgccggcga
     7021 gactctgcgc gacctcagcg ccagccacac cttcgtcggt ggcctcctgg tctcctccac
     7081 caccgcgcag tgagccacgc cgcccctgcc cacagccagg gccccgcaga ccagccccgg
     7141 gcacggcgac aggggtggtg accaccccac gcgtcacggt ctccccctgc gtcatcctgg
     7201 aaccatgagg atcgaggttc tggtcgtgcc ggactgcccc cacgagaagg cggcggtcga
     7261 gctgctgcgc cacgcgctgg acgacgccgg gctgacggac gtcacctggg acaggcgggt
     7321 ggtggccgat caggacgcgg ccgagcggat cggcttcgcg gggtccccga cctttctgat
     7381 cgacggacgc gacccgttcg ccgagcccgg tcgcgccccc ggactgacct gccggatgta
     7441 cccgacgccg caagggcccg ccggcctgcc cacccgcgac cggttgcggc aggcgctgac
     7501 ctccgcctgc ccggccggcg gcgctccggc gggggcgggt ggcgaggcgc agcaggcgag
     7561 ggagcagcgg cggcactggc aggacaccta cgccgcgcac cccggcatgt atggcgccga
     7621 gccctccgcc ccggccgtgc acgcggccgg cgtcttccgg gccgcgggcg ccgaacgcgt
     7681 actggaactc ggtgccgggc acggccgcga cgccctgtac ttcgcccggg agggcttcgc
     7741 cgtccacgca accgacttca gttccaccgg actcgatcag ctgcgcgaag cctcccgcgc
     7801 ccaggggctg gccgaccgga tcgccaccac cgtccacgat gtccgcagtc ctctgccgtt
     7861 tcccgacgac tcggtggacg ccgtcttcgc gcacatgctg ctgtgcatgg cgctgaccac
     7921 ccgcgagatc cacgccctgg tcgccgaggt ccgccgggtg ctgcgcccgg gcggtgtctt
     7981 cgtctacacc gtccggcaca ccggcgacgc tcactacgcc gccggtacct cccgcggcga
     8041 cgacatctac gaacacggcg gcttcgccgt ccacttcttc ccacgccggc tggtcgacgg
     8101 cctcgccggg ggctggcgcc ttgacgaggt ccacggcttc gaagaaggcg aactgccccg
     8161 ccgtctgtgg cgcatcaccc agaccctggc ctgacgcgca acagcaatcc cgcccgggcg
     8221 actacgcacg gcccggcccg tccggatgcc acgaccccgc ccgcgcatgc cctccacacc
     8281 ctgcgaaccg actggtgaga agggttatcg gccccggtcc cgccgcttgt attcctggaa
     8341 tacccggccg gcggagggcg cgcggaagca ctgtcgggct ccggccgcac catgccgggg
     8401 tttgtgcctc ctgaatgcga ggccgccccc tttcacgccg taccgagatg atctcccgcc
     8461 tgtttcgctt gatcctgcgc acggccaccc tgcgcgccac cggccgtttt gctcacgtct
     8521 gttcacgtcc cgggagggaa tgtgtccaca ccggacagcg tcaccggttc cgctaccgaa
     8581 gagcccgcac tcgatcccgc agacaccgcg ctcaccagtc tcagtacaca ggccgcgcgc
     8641 caactggcca ccaccaccaa gtccgtgccc cagatgcagg ccatcacctc gcgatggctg
     8701 ctgaaggcgc tgccgtgggt ggacgtcaaa ggtggcacct accgggtcaa ccggcgtctg
     8761 caactccgtg tcggccgggg ccgtgtccag ttcgagcaga acggcgcgga cgacatcaag
     8821 gtgatcccgc agaccctcac cgaacttccc gtcctgcgcg gttaccccga tatcgacgtc
     8881 ctcaaggagg tcgccggccg gttccgcgtc cgggaggtcc gggccggcca ggtcctcttc
     8941 gaggcggggc agcccgccac cgaggcgtac ctcgtcgtcc acggccggtt cgcgcgctac
     9001 gcggccggca agtacggcga ggaggaggtc atcggcgtcg tcacggacgg cgaccagatg
     9061 ggggacgagg cgatcggcct ggccgaaccg cgctggcaga cctcggtacg cgcccagacg
     9121 gcgggcgtgc tgctggtgct gccctgggac gtggtccagg agttcaccga ccgcgtaccg
     9181 tccctggcgg cgcacctggc ggcctacgcg gagcagcagc agcgccccgt gaaccgcaag
     9241 ggcgaggcgg aagtgccggt ggcggcggga cacgtgggcg agccgacgct gtccggcggc
     9301 ttcgtcgact acgacctcac cccgcgcgag tacgaactct ccctgaccca gaccgtgttg
     9361 cgggtgcaca gccgggtcgc cgatctctac aacgagccca tggaccagac gcagcagcag
     9421 ctgcggctca ccgtcgagga gatccgtgag cgccaggagt gggagctggt caacaaccgc
     9481 gagttcgggc tgctgcacaa caccgactac ggccagcgca tcagcaccta ctcgggcccg
     9541 cccacccccg acgacatgga cgagctgttg tccatgcgcc gcaagacacg gctgttcctg
     9601 gcccacccca aggcgatcgc cgccttcttc cggcagtgca acaaacgcgg tctggtaccg
     9661 ggcacggcga acgtcgacgg gcacgaggtt cccgcctggc gcggcgtccc gatcttcccg
     9721 tgcggcaaga tcccggtcag cggcgagcac accagcagca tcatcgcgct gcgtaccggg
     9781 gaggcggacc agggggtcgt cggcctgcac cagaccggcc tccccgagga gttccagccc
     9841 ggcctgaacg tccgcttcat gggcatcgac aacgccgcga tcatcaagta cctcgtcacc
     9901 gcctactact cgatggcgat cctcgtgccc gacgcggccg gaatcctgga gaacgtccag
     9961 atcggccgga gcgccgactg accgggtgga gtacccaacc atgagcacgc cccccgacac
    10021 cgcggccggg tattcgctgc ccggcccgcc gaacctcgcc cgcaccctgc gggcccgacg
    10081 tggcggagcc gtccccgggc tgaagtaccg gcccgccgtc cccgccgacc cggagaaggc
    10141 cggggagatc gaccgcaggc tggagtcctg ggcccgccgg ctggatctct tccccgcgca
    10201 gtggaccggg gacttcgcgc agttccaggt cggccgggca gtcgtcctgc agcatcccgg
    10261 tgcggccgat ctcgaacgcc tcaccgtcgc gggcgagttc ctgctggccg agaacatcgt
    10321 cgacagctgc tactgcgagg aggacgaggg ccgcggtgcc tcacgccgca gcctgggcgg
    10381 tcgtctgatc ctcggccagt cggccctcga cccgttccac ggcacgcccg cactggagga
    10441 ggagtggcgc cgtggcatgc aggccgacgg cccgctgcgc tcgtaccact gggccatgca
    10501 ggactacgcg gccttcgcca cccccagtca gacgggccgg ttcgtccatg acatggcccg
    10561 gctgcacctc ggctatctcg ccgaggcgtc ctggtcacag acgcggcaca tgccgcatgt
    10621 ctgggagtac ctggtgatgc ggcagttcaa caacttccgc ccctgcctgt cgctcgtgga
    10681 cgccgtggac ggctacgaac tgcccgaagc gctctacgcc cgccccgagg tccagcgggt
    10741 caccgccctg gcctgcaacg ccacgaccat cgtgaacgac ctgtattcct tcaccaagga
    10801 gctggccagt gaccccaacc acctgaacct gccgcaggtg gtggccgcca acgacaaacg
    10861 cggtctgaag gccgcctacc tgaagagcgt cgagatccac aacgaggtct tcgaggcgtt
    10921 cgaggcggag tcggccccgc tggctgccgc ctcgccgctc ctcgaacggt acgtccgggg
    10981 cctgtccgcc tgggtcgccg gcaaccacga gtggcacgcc accaacaccg accgctacca
    11041 cctgcccaac tactggtaga ccgatcccgt gcaccaccgc aaggagcgac cgttgaccat
    11101 cgcacacgcc gacaccgtcc gcacgccggt gccgacccag tccacgtacc agtcccgcgt
    11161 cgcggactac tggaacgccg aggaaaaccc ggtcaacctc gaactcggaa agatcgacga
    11221 cctgtaccac caccactacg gcatcgggga cgccgactgg tcggtactgg acgagccgga
    11281 ccccgacctg cgccgcgagc aggtcaccgg cgaactgcac cgcctggaac acgcccaggc
    11341 cgaactcctc gcctcccacc tcggggacct ctcccccacc gaccgcgtct tcgacgccgg
    11401 gtgcggacgc gggggcggca gcgtggtggc gcacctgcgc tacggctgcc acgccgacgg
    11461 cgccaccatc tccgccaagc aggccgactt cgccaacgag caggcccgca aacgcggcat
    11521 cgacgacaag gtgcgctacc accaccgcaa catgctcgac accggcttca cctccggcgc
    11581 gtacgcggcg tcctggaaca acgagtcgac catgtacgtc gaactggagc tgctgttcgc
    11641 ggagcacgca cgcctgctgc ggcgcggtgg acgctacgtc acgatcaccg gctgctacaa
    11701 cgacgcctac ggccgcgcct cccgcgaggt ctccctcatc aacgcccact acatctgcga
    11761 catccacccc cgctcggcgt acttcaacgc catggcccac aaccggctcg tccccgtaca
    11821 cgtccaggac ctgacggagg ccgcgctgcc ctactgggaa ctgcgccggc aggccgacca
    11881 cttggtcacc ggcatcgagg agaccttcct caacgcctac cgcaacggca gcttccagta
    11941 cctgctgatc gccgccgaac gcgtgtgaac accccggggc cgcgccgctc gcggcgcggc
    12001 cccctgttgc ggcacccggc agccggcgcc ccgctgaccc gtcggagctg tcacgcgggc
    12061 tatggtccgt cccatgacac tgtcgatgcg ggaacgagag ctttttctgg cggaacccca
    12121 catcggtgcg ctgtcggtca tcgagcggcc tgaccgcgca ccgctgacgg ttcccatctg
    12181 gtatcagtac acacccggtg gcgaactgtg ggtacgtacc gggcccgact cccggaaggc
    12241 gcgggcgatc cggtccgcag ggcgtttcag cctgatggtg cagcggaccg agccgacggt
    12301 gcgctacgtg tcggtggaag gaccggtgac caggaccgaa ccggacagcc gcgagcggtc
    12361 ctgggagatg gccgcgcggt acctccccca ggacaaggtc gccgacttcg tggaatacga
    12421 ccgcacccgg ctcggtgagc acatcgccgt ctacatgcgg ccggaacact ggctgtccgc
    12481 cgacatggga tccctctgac cacacgagcg cgcaagcccc cacgcaaccg cgccgcgccc
    12541 actcacttca ctcccgccac cgagcgcccg gctccccggt acgagccgag cgcggcatcc
    12601 catcccgccc cgcccccggc acgcacggcc cggcatgcgt tacccgccat ccacaactcc
    12661 gttgtcagcc acggcatttc gtcgacagcg gagacgacat cgggtatagc gtcgacggac
    12721 agcaatgcac agaagggact tgcagcaatg aagttagcca ttcgtaccgg actggtcgtc
    12781 gcgatagcgg cctctgcctt cgcggcgctc gccccgaccg ccggtgccgc caccgccagg
    12841 agcgaccagg cggcgaatga accgaactgg gcgaccacga gcgctgtcgc gccggtcgcc
    12901 gccggcgatc acgcgatggg cgcccgcctg gccgcgaacc cgaccacgat caaggccgcc
    12961 gcgtacaacc aggcccggag catcctggcg aaggccggca gcgacagcgc ggccaagtcg
    13021 caccccgtcc acggcacggg cgacgtgccg gtcaggtacg gcaccagcct gctggccggc
    13081 tcgcgggacg agttccggtc caaggaccgc aacgttccgg acaagaagtc gggcatgtcg
    13141 ccggctcact accaggcgat ccacgacgcg gcgcgcacca tgggcatcga ccgctggtga
    13201 cgtagccgac atcgcctccc ttgtcactac cgctgacggg aatcctcctg tcaggggccg
    13261 aggggggctg ctgggcaggg ccggtgcggt ggcggtattc gttgggcggt atggccgccg
    13321 gaccgcacgg gccttcgtct tccacggcac ggtcaccgtc acaccgatcc ggctgtggct
    13381 gcgtcagcga ctgccgccca gtccatcggg tcgatggcag acggcctcga cgttgttccc
    13441 atcgggatcg cgaacaaagg ctccgtagta ggactcgtgg tagtccggcc agagccgggg
    13501 cgcgtgcagg acctcggcac ccaccgcaag ggccgctgcg tagaagccgt ccacggcggc
    13561 gcggtcggct gcggcgaatg cgatgtgcag ctcgcgtgcc ggcgcgggat ccgtcgcggg
    13621 gaccagccac agcgggtggc ccgtgacccc gaagccgatg ttctcgccga actgtttcct
    13681 acgctcgcca cctaacggag caagtacggc atcgtagaaa gcagcgctgg cagcgaggtc
    13741 gcgcacctgg atggcgatat gatctagcat gcgccaaccc tcccccatcg caggggagtt
    13801 gtcgcgcggt tttcccttca tccgctcccc ggccgggcgc aacggtacac gccggtgctc
    13861 cgacccatcg gcagccgcat tcccggatgt cgggatttcg gtggcccgct gccgcccggg
    13921 gagtggggat cgtgcgccac cagtgcggtg tcggctcgcg gggtcaggtg agggcggcga
    13981 cgagcagggc gaaggcggcg atgatgacgg cgacgcggac gtagtggtag cgggcccagc
    14041 ggttcatctg ctccttccag tcctcggggc ggttctcggg ggtccacgtc ttgttccggt
    14101 tgttgatcgg gacgagcagc aggagcgaca tgatcacgct gaggatcagc agcgcgccgg
    14161 cggtgacgac gaggccggtg ccgtggtggt gccatccggc gatggcccag accgcgacga
    14221 ggacgagcga ggtgatgtac cagaccggca tcacggcgcc gagcatccgg cccccgtggg
    14281 cgtggccgag ttggccgctg tcctcgggga gggcgttgag gatcgggttg aggacgaaga
    14341 gaacggagaa ctccaccccc accatcaggc cgaggaccac ggtggtgaag acctcgagtg
    14401 cgttgagcat gatgacccct cctgggatct agcgccgcta actgatgagg caacgctagt
    14461 actactgccg cttgattgtc tagcgatgct aggatcgaat catgtcggta caggaacgca
    14521 agcagcgcga acgggcggag cgcgaacgcc tcatcgtggc gacagcccgc gaactcgccg
    14581 agcagcaggg ctgggacgcg gtcaccaccc gccggctcgc cgagcgcatc gaatacagcc
    14641 agcccgtcct ctacagccac ttccgcggca aacgcgagat catcggcgcc gtcgccctcc
    14701 aaggcgccac cgagatggcc gcggcggtgc gtgccgcagc ctccagagcg aacagcccgc
    14761 gcgagcgggt cgccgccctc gcccgcacct acctcgactt cgccgcacgc aacccggcgg
    14821 tctacgacgc catcttccag ctcgacggcg gcctggcgtt cgcgcacgag gacaccccgg
    14881 aacctctcaa ggacgccttc gccgcgctgc tggagagcct cggcgaggtc accggggacg
    14941 gcgtccaccc ggggctgttc accgaggtgt tctgggcggc cctgcacgga ctggccaccc
    15001 tgacccgggc gcgacggctc ccgccggagg acaccgagcg cagagtggag ctgctggtgg
    15061 accggctcgc cgtggtctga cacaccgtcc cggcgagcac gcagccgggg ccctcggacc
    15121 ccgccactgc ctgcctgcgg caacgcttcc ggtcactcgc gcccacacgg cgcagccgca
    15181 gaccgccggg ccccgtaccc cagacgggcg cccgccccgg aagccgcggt gctcattgat
    15241 cacgacccga ttcgcgccct ggtcgagtgg gaggacttcc ccctgtccct ggcccgcatc
    15301 cctggttctt ccgttctcac cagtcggtgg cgggccgggt tcagctgact ggcagctggt
    15361 atcgaagttt ctccttcgcc tgggccccca gccggttgta gaacctgatc gcatccgtgt
    15421 tccagggcgg agtctgccac tggacttgtc cgagccccag tgcatgcgct tcggccacca
    15481 cagcctccac cagcagggag ccgaccttca ggccccggtg accgtcgcgc agaaacagac
    15541 aatccatatg gaggtactcg gccccgtccc acgtggagat ctccggggcg cacgacgcgt
    15601 acccgatgat ctccccgtcg ttcaactcgg cgacaaagca ccgcaatcgc ggggtctccg
    15661 tactgaacag cagtacctcc aggcgccgag ccaggtccgt cggtggaggc ggcgctttct
    15721 cgtaggcggc atggtcggcc accaggtgga cgacctgagg aagatcggcc gcgcgtgcgc
    15781 gtcgcacccg ggccgctccg gcgccggtca ccggacctcg ccctcgagca catccccgcg
    15841 ccaggccacg agccgttcgg ccaccgcacc gtggctgtcc agcacgtgac gggtgagggc
    15901 atcgcgttcg tgcgccagga cggccgcctc ccacacgcac ggggcgaggc ccacccggcc
    15961 aggccggagt tgagtggcgt cgccggccgg gccggtgaag atggcgaggt cagacatata
    16021 gccctcgatc caggtgtgca ccaggatgta gtcgccgtcg ccaccggcat ggatgagcag
    16081 cacggagagc ccaagagaac cccgcgactg tgccgacgac aggtaatcgg cggcgatccg
    16141 caccgcgttc tgaacgtcct ggtccgtcac actccgtccg ggcgcctcga tcgcatagga
    16201 cttcaccagg tgcccggcaa ctgcacggct gcccagtggt cgcaccgcgc gggcgtggta
    16261 gtcatcagcc agcgccagca acgcatccga atcgacagca gccaaagatt cgccgagttg
    16321 ggattccgca agatctctca tccgaccatc atgcacgcct acgccatgcg cccacagggg
    16381 cacacgatcc gccggccagg cagccacctg tcacacccac ctgcccggcc tccacccgcg
    16441 cctcgatgat ctggatcaaa gacctcaccc aggccgccca gtgatcacga ttcgatacgc
    16501 gccctagccg tcttggtgcg gcagccgctc aagcgggaag aggatcgggc tcagcaggtg
    16561 gaggctgcgg cccggcgcgg gcttgttgtg tctcttggac ctgatggcgc tgaggagttc
    16621 gtcgatcagc tcggcgagtt cgtcccggtc gagccagagc ggaatctggg tgtagcccac
    16681 cgagtcggcg atcgggtcgg tgtcgtcccg gtcgaggtag gcgttgaagt cggcatgcag
    16741 gccggccagc gccgcggtga agccctgccg gtggtcgtcc cgggacatgg ccgcggcctc
    16801 gtcggcgtcg atcaccgcac gctcgcggcg cagtcggtag tggcgttcga cggcgccgtg
    16861 cacccgctgc tcgtcggtga cttccaacac cccggcgtcg gccagcagtc cgacgtgccg
    16921 gtacacggtg gtcttgggga cgtcgggaag gctcgcgcac aggtcggagg tggtgcgcgt
    16981 gcgcccaccc gacatggcgt gcacgatgcg caggcgcacg ggatgcagga gcaggtcgag
    17041 cttgtccacc cggatacgat cccacatccg ctaccgcccc cgaagtcggg aaagcaacag
    17101 gaaggggtga gccatcacct ggcaaccgcc ccgagcccgg cgcgaggcgg gcccgaaacg
    17161 ggcccctgag ccgttccgtc acgggaagtc ggcatgagcc ccctgacccg atgcccgctc
    17221 aggccgcatg agccaccgtg cgggccgcac acgagcaagt ggccgaccgg gcccgcggct
    17281 tcggtgtgca cggcacgctg cacgccctgt tcgtctccga agcctccggc cgtatcgcga
    17341 aggtccccgt tcccgggcgc gggaccgact gagaaccggg acgaacggac tcgtacgccg
    17401 acatccctgc ggcggtaacg gggcggcgac cgaccactgc cgcgcgcgta gttgacgtcc
    17461 gccgtggagc cgtggcggta tgccgaccgg tacgccgacc ggtatgccgt caggtggtgg
    17521 gaccgctcca gtaggcgtcc tcccaccgct tcgcgtcggg gctgaactcg acctcgatcc
    17581 ggtcggcggc acccggcggc agggagaagg cgtacttgcc cacggcttcc ttgccgggga
    17641 ggacatagcc ggtgaggacc ttctgccgcc cgcttccgtc gatcaccagc tccgtcgacg
    17701 ccccgtcagc gtcgttgacg ctgggcagcc cggtctctac ggcgacccgc cggccaccgg
    17761 tgttcaccac cgcgaccgtg acctggacgg ccttgttccc cttggcgtga ccgaggacgt
    17821 aaccgtccgg gctgaacggc accggcttgc cgaccgtgac tttcagaccg tcgccgaagg
    17881 tgtacgactt accgaaggac aagtgccggg ccttctcggc ggcagccgcc gactccctgg
    17941 ccgcctcggc cttggcgcgc gcatcggcgt cgacctcctt cacgtgcgca cggtcgcggt
    18001 cgaccacccc cttgaccaac acgacggtga acgccgcgcc gcccgccgcc gcgaccagac
    18061 ccaggatgcc cagaacgaca ccgctgaacg ccatggcctt gttggtggcc cgacccgtgc
    18121 gcacccggct cagcccgata ccgccgaaga tcacggccaa caatgccggc agccaggaca
    18181 gccagaacag gaagatgaac gcgcctagga cgaggccgac aagagcgagt accagcgccg
    18241 tgatgcccat gccgttgctg ggctgcgggg tccaggccgg cggcgggcac ggcgcccggt
    18301 acgcgtcgct ctcagcgggc ggcgcagccc acgggtcgcg gtgccggggc agtggatccc
    18361 cggtcgtggg gccgtcggga gagacgggcg tggtcatgca gaatccttca gccagaacac
    18421 tcggtgaatt tccgacaata ccaggggttt taccttttca ttacccctca cgggtggggc
    18481 cggcacacca cccaggcacc caggcaccca ggcacccagg cacccaggag cggacttgta
    18541 gttggcgcag cgaacgctgc gctgcggaca tgtgcccacc tgcggcggcg atgcgcactc
    18601 caccgtcacg gccgcacacg aaccggttcg gccttgccct ggatcaccgc gcgcagggag
    18661 gcggatgtgc ggtcgatgtg ctgggccagg aggtcggccg cggcgcgggg gtcacgggcg
    18721 agaaccgcgt cgagtagtgc ttggtgttcg cgggccacgt cgcggtcgta gtcctgtccg
    18781 acggggccgg accagcgcag gtagatcgct gcggcgatcg gctccaccag ctcaccgcgc
    18841 gaggccgacg tcctgcagaa ggaactgggc tatgacgccg aggtactgcg caaagcgggc
    18901 cccatcgacg aacaaccgcg ggccgccgcg ccggacggcc tcgacgtggt cgtcgacaac
    18961 gtgggtggcg agcagccgaa ggcagcgatc gggttggccc ggcgcggggc gcgcatcgcg
    19021 ttgatcggca cactggccgg gcagctcggc gactcggcca ccacggaaat cgacccccat
    19081 gccctcatcg caggcagcat cgccttgcgg ggcgcagcgc tctacgacta cctcgacatc
    19141 atccccgagt ggaccgactt cttcgcacgc gcactgcgcg acggcacgct caccttcccc
    19201 cgcaccgtgc tgaccgggct cgaccaggca ccgcgcgctc tgcgggagct agtggagggc
    19261 cggcacctgg gtgcagtgca catggagctt tgatccggtg ccggtgccgc ctcggcgccc
    19321 tccagcgcag cccgttcctc gcccgacaac gtcgactcgg ccttcgtccg ccccgtgtgc
    19381 caagacgatc agttggccgg agccacaccg ccaacggggc tgcttcctga tgcgctgggg
    19441 gaaaagttgc gggtcgctgt cgatccggcc acgtcccgtt cgacgtcatg atgtgcggcg
    19501 cctcgcccca cgatgacgcg acaggacctg acgaggaaac acgtggatca actgctgaga
    19561 atcatgaact tcaacgtctc gcgtgacgga atcggtgccg gtgagcacca gagtctccag
    19621 cggccgttcg ggcacgatca tcccgagagg ctgttcgcct gggccggagc gacggcgagc
    19681 tggcccatgc gcacggatcc cgggggaagc cggggcctcg acgactactt cacgcgagac
    19741 ttcacacgca acatcggtgc cgagatcatg ggccgcaaca agttcgggcc ccagcgcggg
    19801 ccctggcagg accatgagtg gcgcggctgg tggggggagg agcccccgtt ccacactccg
    19861 gtgttcgtca tgacccacca ccagcgtccg tcgttcacgc tctgcgacac cacgttccac
    19921 ttcgtcgacg gctccccggc cacgatcctg gaacgggcgc gggaagcggc acagggcaag
    19981 gacgtccgac tcggcggcgg ggtcaccatc atccggcagt tccttgatgc cgacctcgtc
    20041 gacaccatgc atgtggcggt ctcgccggtc aagctcgggt ccggactacg actctgggag
    20101 tctcccgatg agctgctcga ccggttccac ctggaggtgg tgcccagccc gagcggcgtg
    20161 acgcaccacc tgttctggcg aaggtgagtg acgcgaggcc cacttgagtt cacttccggc
    20221 gggtcggccg gaagcagacg gggtgccggg cagggccgtc acactctccg cccggcaccc
    20281 gagcgcacga gtcggccccg gatgctgcgc cacggggaaa gggcggcggc cgaggccggt
    20341 gtgtggtgaa ctctggtggc tcaggcggag attccagctg gccaggccgg gctcgtcatg
    20401 ccgaaccagg gccgggctga ggggctcggg agccgggcgg tcggagcccc tccacaggcg
    20461 atgggtccct cgcgcagggc cgtgagggac ggggcatcag ccggagcgat gcgattcggg
    20521 gcggtgtggc cggagccgga gctggcggcg gtagcgcgtg cgcctgctgc ttgaggccgg
    20581 gcggtctcca gcggcggggg cctgcgggga cttcccgacg gctcctccgt gcagcatcag
    20641 cagtgtgccg gtggcgaaga ccacgaggaa cagcgtgatc gatccggtgg ccatcagtac
    20701 ggcgtgggcg tggagcatct ggttggccag ggcgagaacc acggccagca cactgcttcc
    20761 cgcggacgag agctgtggct accccggtcg ctgcgctccc ccggcggccc gagccccagc
    20821 cgcacacgtg tccgtctgcg agggcacgtt catggccgat ccctgcctcc gccaggtcta
    20881 ctgctcagcc atctgccgtc gggaagcgga acgacagcgt gaacgcgagc gggcccggtt
    20941 ccgcgccgag gtggacgcgg cgggcaaggt cggtgggttc cacaccgcgc aggtggtgga
    21001 cgccgaaccg gacggagagc cgccctggct ggccacggcg tatgtgccgg gcccgacgc
//
