LOCUS       NZ_CP047146            41122 bp    DNA     linear   CON 30-JAN-2024
DEFINITION  Streptomyces sp. GS7 chromosome, complete genome.
ACCESSION   NZ_CP047146
VERSION     NZ_CP047146.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. GS7
  ORGANISM  Streptomyces sp. GS7
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9067183)
  AUTHORS   Li,J., Ni,J. and Li,Y.
  TITLE     Multiple polyene macrolides produced by antifungal Streptomyces from
            gut of Macrotermes barneyi facilitates the termite-fungus mutualism
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9067183)
  AUTHORS   Li,J., Ni,J. and Li,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-DEC-2019) State Key Laboratory of Microbial
            Technology, Shandong Unversity, 72 Binhai Road, Qingdao, Shandong
            266237, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 20-NOV-2019
            Assembly Method                   :: SPAdes v. Nov-2019
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/30/2024 05:53:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,019
            CDSs (total)                      :: 7,925
            Genes (coding)                    :: 7,616
            CDSs (with protein)               :: 7,616
            Genes (RNA)                       :: 94
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 309
            CDSs (without protein)            :: 309
            Pseudo Genes (ambiguous residues) :: 0 of 309
            Pseudo Genes (frameshifted)       :: 107 of 309
            Pseudo Genes (incomplete)         :: 258 of 309
            Pseudo Genes (internal stop)      :: 29 of 309
            Pseudo Genes (multiple problems)  :: 79 of 309
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:40:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4888616
            Orig. end                         :: 4929738
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP047146.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Jinfeng Ni.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..41122
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T3PKS"
                     /region_number="18"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     cand_cluster    1..41122
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..41122
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:21122](-)"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..21122)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     gene            complement(<784..>930)
                     /locus_tag="GR130_RS40830"
                     /pseudo=""
     CDS             complement(<784..930)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012948683.1"
                     /locus_tag="GR130_RS40830"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS5/IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSRPGSPHRVVCDANGIPLAVTLTGGDRNDVTRLIPPPAAVPPVR
                     GERG"
     misc_feature    complement(1108..1124)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.88"
                     /tool="antismash"
     gene            1777..3537
                     /locus_tag="GR130_RS21645"
                     /old_locus_tag="GR130_21645"
     CDS             1777..3537
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055: pyruvate oxidase/decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014794.4"
                     /locus_tag="GR130_RS21645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_21645"
                     /product="thiamine pyrophosphate-binding protein"
                     /protein_id="WP_159506231.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 8.5e-48, bitscore:
                     161.0, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 8.9e-34, bitscore:
                     115.3, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEPSVSFASREPLSVSGWLVNALRAQGVEYVFAVPGGPLLSLYE
                     ELANSPGVRLVLTRHEEAAAFMADGYAQASGRLAVVCATTGPGAMHTLTGVASATSDSM
                     PLVVITAQTAASAFGRSGLQDSSGGNWSVDTVEMLRTATKLSTRLAHPGQLPWLFCHMM
                     RTIWNGRPGAVHLSLSSDMMSSPVPDVSIPSPCHAASTVPDAAAVAVLAQELRRSRRPV
                     ILAGQGAKLSGAAGSLQQLAQTAGIPVATTLKGKGVFPEDHAWALGVFGLGGNPAAFDY
                     LLSPEVDLLLIVGSGLGEAAANAFDSRLVTGRQVIQIDLDPLRLGAGCDLDLAVAGDAD
                     TVLRALLAELEDAPAAPCVPDAVLSAAQDQLLVRVPASAIQKDHKVLSASAVVSRMSEQ
                     LPEDTILYVDNGNCLSWVGQHYRSRPDGQIHFSFNVASMGYSTGAAIGGQLAHPGRTVV
                     AVTGDAAFAMSGMELHTAAELGLPVIWVVLNNGGNAMVLNIQESIYGHGSRSMYDCPID
                     AAAIARGLGAQARTAADLDSFTQALGEALEADSPFLIDVHVDPSEVPWALGTRVTSLRS
                     ALTDRRAGRW"
     misc_feature    1846..1848
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            3543..4070
                     /locus_tag="GR130_RS21650"
                     /old_locus_tag="GR130_21650"
     CDS             3543..4070
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1298: putative carboxymuconolactone decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GR130_RS21650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GR130_21650"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_159506232.1"
                     /transl_table=11
                     /translation="MRLPYPRPEDHPEPLKEVPPLNLFRAFGNAPAYTGGLIDLGLVGL
                     GKLVLTPRQRELLILDTATSTGSAYVTQAHVPFGQAVGITGEQASFIRQREPLPGPFLP
                     EEAALLAVGRELLQSATCTGEAIQRAHLLCGARAVTETLILVGYYRLVCGFANALDVEP
                     DGKSTHMLPYAS"
     gene            complement(4519..4938)
                     /gene="panD"
                     /locus_tag="GR130_RS21655"
                     /old_locus_tag="GR130_21655"
     CDS             complement(4519..4938)
                     /EC_number="4.1.1.11"
                     /GO_function="GO:0004068 - aspartate 1-decarboxylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="panD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018538064.1"
                     /locus_tag="GR130_RS21655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_21655"
                     /product="aspartate 1-decarboxylase"
                     /protein_id="WP_159506233.1"
                     /transl_table=11
                     /translation="MLRTMFKSKIHRATVTEADLHYVGSVTIDAGLMEAADLLPGELVH
                     IVDIDNGARLETYVIEGERGSGVIGINGAAAHLVHPGDLVILISYAQVDDAEARTLRPK
                     VVHVDGDNRIVALGADASEPVPGSDTSRSPRAAAV"
     gene            complement(5393..6202)
                     /locus_tag="GR130_RS21660"
                     /old_locus_tag="GR130_21660"
     CDS             complement(5393..6202)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004952014.1"
                     /locus_tag="GR130_RS21660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_21660"
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="WP_159506234.1"
                     /transl_table=11
                     /translation="MTTAPVRSAAAVRAIGDAADGAGPISLDELNERAALLARFDHSYL
                     VPADTFLRIVGRLTDPRRPGGRPFRALAIDDRRAFRYHSVYYDTPELRSFHDHRQGRRL
                     RFKIRERVYADTGERQFEIKLKGPRGDTVKRRRPLTGAGTPLDPDCRGFLAETLRTAYG
                     IGAPAVLEPSLSTDYIRATFVADGERITCDAALVCDDLRTGHTVRCADDLVLVETKTTG
                     HLTEADLLLHAHGIRPAVFTKYCGAFAALHPALPANRWRRAARRAFG"
     gene            complement(6199..6834)
                     /locus_tag="GR130_RS21665"
                     /old_locus_tag="GR130_21665"
     CDS             complement(6199..6834)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004949622.1"
                     /locus_tag="GR130_RS21665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_21665"
                     /product="DUF4956 domain-containing protein"
                     /protein_id="WP_159506235.1"
                     /transl_table=11
                     /translation="MESLRHLIAHLGLDLAAVGVLTFAIYYPRHRRRDLVPAYLALNTG
                     LFTVVTALAEVRGAGGAALGFGLFGVLSIVRLRSDAVQHEEVAYYFTTLVLGLLCGLPR
                     LPFVLTAGLCAALLLIVWAADNPRLLAGTRRAVVTLDTVHEDPAALRADLARRLGEPLH
                     WTVMEVDFVRDLTVVDVRYREPAAAPAERGTVPAAGPAPRTTPAWETV"
     misc_feature    complement(6823..6825)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7330..7884
                     /locus_tag="GR130_RS21670"
                     /old_locus_tag="GR130_21670"
     CDS             7330..7884
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007445829.1"
                     /locus_tag="GR130_RS21670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_21670"
                     /product="hypothetical protein"
                     /protein_id="WP_159506236.1"
                     /transl_table=11
                     /translation="MHHTEVLLIGGRAGVGKTTVGWEVSALLRSESVAHAIIDGDFMGQ
                     VHPAPEGDPHRAEVTESNLTAVWANFAQRGYRRLIYTNTTSVLPEATGMFERAMGAGVG
                     ITRVLLTASDATARTRLVGRELGSELEQELEGSIRKARLLDQRALGETVRVATDGRLVV
                     DIAREVVAATGWAGPHVTRRS"
     gene            7919..>8074
                     /locus_tag="GR130_RS40840"
                     /pseudo=""
     CDS             7919..>8074
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611994.1"
                     /locus_tag="GR130_RS40840"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS701 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGRIASRFARVEPRCRAGEFALGPLSDLPRRNCWTLAEQARNAPP
                     DGLQRLL"
     gene            complement(8156..8533)
                     /locus_tag="GR130_RS21675"
                     /old_locus_tag="GR130_21675"
     CDS             complement(8156..8533)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GR130_RS21675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GR130_21675"
                     /product="hypothetical protein"
                     /protein_id="WP_159506237.1"
                     /transl_table=11
                     /translation="MNTPRRIVATASVLAASLGFLGMTSSSASADDGVRVTKKAAAASD
                     CAFAVFTPGNKYCYNDAGSYDIGPITGVSQVCVYSGWAVYAWAPNPGEPHQRKLQHAAD
                     QCDDYTNVPGNTVVDWVELHP"
     misc_feature    8518..8533
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.75"
                     /tool="antismash"
     gene            8852..11227
                     /locus_tag="GR130_RS21680"
                     /old_locus_tag="GR130_21680"
     CDS             8852..11227
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013124.4"
                     /locus_tag="GR130_RS21680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_21680"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_159506238.1"
                     /transl_table=11
                     /translation="MPERFDTVLRAYRRRAGLTQEELSERAGLSARTIRALESGQGRVP
                     RMASVREVAKALGLGADDQRRLLAAADEREGAAGSVSLGRRRYLPYDIPDFTGRTAEVA
                     RLAELVGGGTASAVVVSAIDGMAGVGKTTLAVHAAHLLADGFPDGQFYCDLHGFTPGYD
                     PVGPASALEALLRMAGVDGARIPHTLEERSALWRTTLSDWRALMVLDNAADAAQVRPLL
                     PGSASCAVLVTSRRRLLALEGAVPLSLGVLSEAEACALVARIAGHDRVADAPEAVAEIA
                     ELCGYLPLAIRMAAARLAHRPAWTAEDLTAELRRGRRRSGPGGNDQAVSAAFALSYARL
                     SPGRQRLFRLLGLHPGADLDAYAAAALAGTDAVTARQWLEELVDVHLLEQYEPHRYQLH
                     DLLRRHTQEVLHETEPPAQREEAELRLLDHYLHTALHARPLVAPGQRLLPFEVARPPAD
                     TPDVSDRASALAWYEAEHANLVAMITHAAARGRNEHVWQYTHLLQHFFDIRGRTLDWVS
                     THELALATTGDLDNRLAHAEILTSLGVACWHAGRYEDAFNRGLEALALCREIGDAWGEA
                     VILTNFGIVQGQLGQSEEAIDLHQQALALYGGVDAPWGEALSLTSLGTVYARLGRAAEA
                     LDHHRRALDRYRGIGDPWGEALTLTNMGTGYRQLGQFGEAVDHHAQALSLSRRMGDRRA
                     ESEILNDLGATYHAAGRRDAARRRHLRALDIARAIDSSPQIARAHQGIAYTLAPDDPDS
                     ARDHAERALAIHGELSAPETAELTAFLDALGQGPAAGH"
     gene            complement(11375..11899)
                     /locus_tag="GR130_RS21685"
                     /old_locus_tag="GR130_21685"
     CDS             complement(11375..11899)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019981560.1"
                     /locus_tag="GR130_RS21685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_21685"
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_159506239.1"
                     /transl_table=11
                     /translation="MTWCARAFRSRCGYELKRCVAHLTGHVRPIADGTLYPAIKRLEKA
                     GWLSRQTEPGSRAAPRHVLTLTDEGRDELRRRLREARGVEISDENHWSTVLAFLRQLDD
                     PDQQTAVLRRRLDFLREPSSFFYEGERPLGAEELGDPFRQGILQIARATSQAEVRWLNA
                     TLKALARQDPC"
     gene            complement(12030..12737)
                     /locus_tag="GR130_RS21690"
                     /old_locus_tag="GR130_21690"
     CDS             complement(12030..12737)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015576467.1"
                     /locus_tag="GR130_RS21690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_21690"
                     /product="AAA family ATPase"
                     /protein_id="WP_159506240.1"
                     /transl_table=11
                     /translation="MIIERAYAHVASRKDEEWPWSVPCVRGLLADGLRFTAPVTFLVGE
                     NGSGKSTLVEALAEGFGLDSWGGSHDWRYASHRPKSVLGERIRFDAAPRGRRMLGSWSA
                     RKGFFLRAETALDALGREGFAPDSVSHGEGFLAAFRGKFLQPGLYVMDEPEAALSFASC
                     LELLGHLHQLVKNGGQVICATHSPLLTALPGADIIEVGEHGMRRVAWDELALVDHWRRF
                     LATPQSYLRHLLD"
     misc_feature    complement(12715..12730)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.96"
                     /tool="antismash"
     misc_feature    complement(12739..12755)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.72"
                     /tool="antismash"
     misc_feature    13009..13023
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.14"
                     /tool="antismash"
     misc_feature    13264..13279
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.91"
                     /tool="antismash"
     gene            13409..16471
                     /locus_tag="GR130_RS21695"
                     /old_locus_tag="GR130_21695"
     CDS             13409..16471
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_functions="other (smcogs) SMCOG1173: WD-40
                     repeat-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014081.4"
                     /locus_tag="GR130_RS21695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_21695"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_159506241.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 7.5e-20, bitscore:
                     70.3, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGALWAGDALGWAAPAQARDEGDREPSVTVSSGTNFAAAVSPDGR
                     WLALDLFTVVWLVPVGGGRARRLTEDAQDASRPSWSPDGQRLVFQSFRDGYYQLWLVNT
                     DGTGLRQLTDDPADHQEPAFSPDGRHIAFASDAENMNAIWVMDLGAGTSRRVTTAKARE
                     ITPTWSPDGRRIAFTVGDTAIDVVELAGGARSTAVTAPTGTTLCGPAWTPDGTRLAYTR
                     FTGRTADLVVGERTLTSGEDVFGFPPTWLSGTELVYTADGLIRRRTLDGSVREIAFTAT
                     LPLAARDYRRQVRDLTSPAPRPVRGIASPVLSPDGHSVAFRALNALWVMPVGGRPTARV
                     SDGFFNTDPDFHLDGTSLVYGSDRSGTANLWRLNLADGSSTQLTDVPRGAMTPRWSPDG
                     GRIAYQDADGAIWVLAVSDGSVRQVLPALFQPGRPAWSPDGRTLAVAAVRPASLRNKSG
                     TNQILTVDLETGATTYAEPAAHRSVATRGDDGPLWTPDGRSLVFVMESTAWALPVDGAG
                     RATGPARQLTREVTDAVSVGDRGRTLMYLSNGLLRTVPLAGGTPRTVPVPLTYRVHEGT
                     DRLVLRAGALWDGVSRQLRRDVDVVIEGTKVAGVVPAGSAVGGRIVDASGLTVMPGLID
                     LHTHWFMRGRGWGDRQGRLWLSYGVTTARSVADPVYQMVETRESSEAGVRVMPRFLGTG
                     EALDGNRVLYNAMRPVQSAAQLDLELSRAEALAYDLLKCYIRLPVALTEPVVARAHRMG
                     VPVTSHYAYPAAHTGLDAMEHVGGGNRLGYTHTVSRLGRTSDGVVDLFARSGMPITPTL
                     IYAAVLYAEDRSLLEDPRTKALFPLWEYELVEQLARNAVGPAADTLRFLLAGAVDLLKR
                     VHAAGGLVVAGTDAPLDTPALAMHLNLRALAQGGLSTYDVLRTATANSARVLGLADRLG
                     TVEPGRFADLAVVAGDPLADVKAAAAVRMVVTGGRLHSVDDLLRPFRQAAATTVRRNRI
                     AAPLRGAQADFSHDWHRPGWVETSCSCAPPR"
     gene            complement(16485..17822)
                     /locus_tag="GR130_RS21700"
                     /old_locus_tag="GR130_21700"
     CDS             complement(16485..17822)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (78-425). E-value:
                     2.9e-27. Score: 87.7. Matches aSDomain:
                     nrpspksdomains_GR130_RS21700_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006344608.1"
                     /locus_tag="GR130_RS21700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_21700"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_159506242.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4.3e-25, bitscore:
                     87.5, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAAPGFVLAGGDLHASLENPVLGSVAFLNEVMTRYPSAISFAPG
                     APHLAHLADVDVTAYAARYERHLVEDRGTTAERARNLLHEYGPSRGLINDLIAAALRHD
                     QGIDVPPRSVVVTVGAQEAMLLTLRALCRSRDDLLAVVEPAYVGMTGAARLLDVDLVPV
                     PETADGVDLDALRGACAAARKRGRRIRALYVAPDYSNPSGSVLDLETRQRLLAVADHDD
                     LVLIEDSAYGFTAPPGHALPSLKALDTDCRVVHLGTFAKVCLPGARVGFAVADQPVVRA
                     DGTEGVLADDLAVLKGMVTVNTSPLCQAVIGGMLLAHGGSLAALGDATSAHYRRNLAHL
                     LAALDRELGGATPPGVRWNSPSGGFFVRVRLPVRVDTALLEWCATEFGVLWTPMEHFYL
                     SGGGTDELRLSCSYLTLDRIDEGIGRFAEFLREVAGPPRRGRRALP"
     aSDomain        complement(16548..17588)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GR130_RS21700_Aminotran_1_2.1"
                     /evalue="2.90E-27"
                     /label="GR130_RS21700_Aminotran_1_2.1"
                     /locus_tag="GR130_RS21700"
                     /protein_end="425"
                     /protein_start="78"
                     /score="87.7"
                     /tool="antismash"
                     /translation="ARNLLHEYGPSRGLINDLIAAALRHDQGIDVPPRSVVVTVGAQEA
                     MLLTLRALCRSRDDLLAVVEPAYVGMTGAARLLDVDLVPVPETADGVDLDALRGACAAA
                     RKRGRRIRALYVAPDYSNPSGSVLDLETRQRLLAVADHDDLVLIEDSAYGFTAPPGHAL
                     PSLKALDTDCRVVHLGTFAKVCLPGARVGFAVADQPVVRADGTEGVLADDLAVLKGMVT
                     VNTSPLCQAVIGGMLLAHGGSLAALGDATSAHYRRNLAHLLAALDRELGGATPPGVRWN
                     SPSGGFFVRVRLPVRVDTALLEWCATEFGVLWTPMEHFYLSGGGTDELRLSCSYLTLDR
                     IDEGIGR"
     gene            complement(17819..19210)
                     /gene="dpgC"
                     /locus_tag="GR130_RS21705"
                     /old_locus_tag="GR130_21705"
     CDS             complement(17819..19210)
                     /EC_number="1.13.11.80"
                     /GO_function="GO:0016702 - oxidoreductase activity, acting
                     on single donors with incorporation of molecular oxygen,
                     incorporation of two atoms of oxygen [Evidence IEA]"
                     /GO_process="GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: ECH (305-410). E-value: 4.5e-18. Score:
                     57.4. Matches aSDomain: nrpspksdomains_GR130_RS21705_ECH.1"
                     /codon_start=1
                     /gene="dpgC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018853585.1"
                     /locus_tag="GR130_RS21705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_21705"
                     /product="(3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase
                     DpgC"
                     /protein_id="WP_236573330.1"
                     /transl_table=11
                     /translation="MSADAHPPTPPATGTGADLGPAPEPPLTGNLVEDAATLAEYAAAA
                     DRSLAALPPRPERDAPQQAAAERVLSAARRLRATFLDWHVEAVYGSLTGDRTHHVRLPE
                     LLRAAGEQWPGLVPTEARLDAERKHIQAHKEGLEIDQGLFLRAILRDPASGAHLTDAMR
                     TPSRRALDLLADFTATGRAELESVLVERRGPAAHLTVHNEHCLNAEDDTLIADMETAVD
                     LALLDDRVRVGVLRGGVMTHPKYAGRRVFSAGINLRHLHEGRISFAGFLMQRELGYISK
                     IQRGLHRPDRTGAGTHHPGGAVAGKPWVAAVDAFAIGGGMQLLLVFDRVIAERGAFFAL
                     PAAQEGIVPGAGNLRLSRCAGARQARRVILWGDRIAAGDPGAAAVCDQVVAPEEMDTAI
                     EEAVSALDNPAVVTNRAMLTLAEEPPELFRTYMAEFAYVQATRLYSLDVIGKVDRAWSR
                     AGGRP"
     aSDomain        complement(17981..18295)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GR130_RS21705_ECH.1"
                     /evalue="4.50E-18"
                     /label="GR130_RS21705_ECH.1"
                     /locus_tag="GR130_RS21705"
                     /protein_end="410"
                     /protein_start="305"
                     /score="57.4"
                     /tool="antismash"
                     /translation="KPWVAAVDAFAIGGGMQLLLVFDRVIAERGAFFALPAAQEGIVPG
                     AGNLRLSRCAGARQARRVILWGDRIAAGDPGAAAVCDQVVAPEEMDTAIEEAVSALDNP
                     A"
     gene            complement(19207..19944)
                     /gene="dpgB"
                     /locus_tag="GR130_RS21710"
                     /old_locus_tag="GR130_21710"
     CDS             complement(19207..19944)
                     /EC_number="4.2.1.17"
                     /GO_function="GO:0004300 - enoyl-CoA hydratase activity
                     [Evidence IEA]"
                     /GO_process="GO:0033072 - vancomycin biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: ECH (84-224). E-value: 9.2e-17. Score:
                     53.1. Matches aSDomain: nrpspksdomains_GR130_RS21710_ECH.1"
                     /codon_start=1
                     /gene="dpgB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF042431.2"
                     /locus_tag="GR130_RS21710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_21710"
                     /product="enoyl-CoA-hydratase DpgB"
                     /protein_id="WP_159506243.1"
                     /transl_table=11
                     /translation="MTRKNDSRADHQVGTDGQAPPGPAADHRVHTHGQPLPALIADLDA
                     ARERVEDAGAGAVLVLALGPATTAPWPGPGVAVHEVNKWERALRRVERLDAPVVAVAEG
                     SCAGPAADMLLVADVRIARTDLRIALPRNDDRCWPGMALYRLVHQYGVARSRRIVLCEA
                     RLTAERALAMGLVDEVTDEPQAALDAALATLRTVSGTDWAIRRRLLLEAHDATFEDALG
                     AHLAACDRELQRMRAGELREVRP"
     aSDomain        complement(19273..19692)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GR130_RS21710_ECH.1"
                     /evalue="9.20E-17"
                     /label="GR130_RS21710_ECH.1"
                     /locus_tag="GR130_RS21710"
                     /protein_end="224"
                     /protein_start="84"
                     /score="53.1"
                     /tool="antismash"
                     /translation="ERALRRVERLDAPVVAVAEGSCAGPAADMLLVADVRIARTDLRIA
                     LPRNDDRCWPGMALYRLVHQYGVARSRRIVLCEARLTAERALAMGLVDEVTDEPQAALD
                     AALATLRTVSGTDWAIRRRLLLEAHDATFEDALGAH"
     gene            complement(20001..21122)
                     /gene="dpgA"
                     /locus_tag="GR130_RS21715"
                     /old_locus_tag="GR130_21715"
     CDS             complement(20001..21122)
                     /EC_number="2.3.1.246"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /GO_process="GO:0033072 - vancomycin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="dpgA"
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024: chalcone and stilbene synthase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020122447.1"
                     /locus_tag="GR130_RS21715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_21715"
                     /product="3,5-dihydroxyphenylacetyl-CoA synthase DpgA"
                     /protein_id="WP_236573332.1"
                     /sec_met_domain="Chal_sti_synt_C (E-value: 4.5e-19,
                     bitscore: 67.9, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVMLAPPHTQPAVHNGTLPSGVLPRIRAVGTAVPPESYTQQDIL
                     DIFGVTDERIRSVFLNSAINTRHLTLPPPGPNRERRVETQGELLRKHVNTGIDMGSRAL
                     ETCVKEAGAGLSDIRYLCCVTSTGFLTPGFSALLIRELGLRVDCSRLDVVGMGCNAGLN
                     ALTAVAGWAAAHPGQRAAMVCVESCSSAYVFDGTMRTSVVNSLFGDGAAAILVEAGDAP
                     GQDTSGPALAGFSSRIIPEAADAMRYDWDDDEGKFSFFLDRDVPYVVGAHAEEAVDALL
                     AGAGLRRTDVDHWVVHSGGKKVIDSVRVNLGLTKHDVRHTTGVLRDYGNLSSGSFLFSY
                     ERLVAEGTVARGDLGVLMTMGPGSTIETALARW"
     misc_feature    complement(21066..21068)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(21327..22553)
                     /locus_tag="GR130_RS21720"
                     /old_locus_tag="GR130_21720"
     CDS             complement(21327..22553)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="GR130_RS21720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_21720"
                     /product="MFS transporter"
                     /protein_id="WP_159506244.1"
                     /transl_table=11
                     /translation="MQAAETTPPQPTQTSDRGSVLAALVFTFVTNIDMTTVLTMLPVAV
                     FGGTRVAPLTFSLALSIQVVASLIGGIVVPMVFRGVNSGWMLSISALLKSAGFVALLAT
                     VHPPGLFVFAVLAGFGRGVSKVAVRVLLTDATVEKDRARAFQLFFVVMNVALLLAPLAA
                     EAADRFHVARYALVLLLLLELAGGAWAGATARRLTSDTGKAKRLAVGGGLGLLLRPGPV
                     AVLAYTLVAYFAMGFIMAMFLLYDEVNPALSGYRELFLSFEPLALIVIQLAMMPVLAQT
                     GRRAVYAGAAITCGTGVLLSFTSSLVLVLLGLALFAFAECLALPQSQVDAGKAVAKEQV
                     SAMLSLVTIMSAVGEMAGNVAAGWIVRNADDLLPSATASAMAVAVVVLAGFAAAGYGID
                     RAVSAREVA"
     gene            complement(22540..23583)
                     /locus_tag="GR130_RS21725"
                     /old_locus_tag="GR130_21725"
     CDS             complement(22540..23583)
                     /GO_function="GO:0008171 - O-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042: O-methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013087.4"
                     /locus_tag="GR130_RS21725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_21725"
                     /product="methyltransferase"
                     /protein_id="WP_159506245.1"
                     /transl_table=11
                     /translation="MSGDGVRRRLIGQITAYRTSKCLYAAVELGIPDLLARRPMTAAEL
                     AAETRTEVDPLRRVLDHLVVAEALGLDASGAYVGTEASRLLCRDAPDGIANWVRCELQE
                     GYWHSWDRLVEQLRTGTPAFELTHQERFFEWLARSPEISDLFDATMRDGSRDLDGGLAA
                     AIPLRPGQTVVDVGGGDGSLLAALLTASPGARGILFELPREKTEVVPALAALIAAGRAR
                     VERGSFFDGVPPGGDVHVLKRVLHDWDDERASQILGRCRDALAPGGRVVVVDMVLDDDR
                     RVPVGRSLDVLMMILMAGRERTAADFSALGTAAGFLPAHVTATGTPLSVVELSLPAPER
                     PEPHAGR"
     gene            complement(23580..24545)
                     /locus_tag="GR130_RS21730"
                     /old_locus_tag="GR130_21730"
     CDS             complement(23580..24545)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF020032.4"
                     /locus_tag="GR130_RS21730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_21730"
                     /product="hypothetical protein"
                     /protein_id="WP_159506246.1"
                     /sec_met_domain="RimK (E-value: 7.7e-11, bitscore: 40.8,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRRPTEPVLTWICHPDDLTPDYAAAIEADMTKEYTAAAERNGFT
                     FRFLPANELVPVVADRPRLLHRGEDLLARRHCYLVDDVSADPQAAHFLRALYRTVDASD
                     SVLLNRALRGPECLERDKLAMMLRAASLDVPTPRTVAVPFGRYARQALPVVREVVGDGP
                     YVVKPREMGMGAAVLRVDTPEQLSAALDVVAQTGQNYLVQECLPITGDLRVMLVGGEVL
                     VSLLRRPAAGRYRANLRQGGVAELDPDIAGVREMCLRIAGSLDAGYLHVDWLMTENGPV
                     LGEWGTALAGFSLMPEPARTKVADAFFQWAHRMLTGVGER"
     gene            complement(24580..25812)
                     /locus_tag="GR130_RS21735"
                     /old_locus_tag="GR130_21735"
     CDS             complement(24580..25812)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (58-406). E-value: 6e-23.
                     Score: 73.5. Matches aSDomain:
                     nrpspksdomains_GR130_RS21735_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1109: 8-amino-7-oxononanoate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF005697.0"
                     /locus_tag="GR130_RS21735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_21735"
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_201304963.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 8.1e-21, bitscore:
                     73.4, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALLEISKNWLTNRLENTTDALALATERDLTSHVFHCRRGKVVEL
                     ADGSEAVEFVSCSYLGLEVHPQLLHSAKEAIDRAGVHFASARTRMRLDDLEELESILDR
                     IYGLRSVTAFTSVGNVHLGVLPLLAADALPSYPMAEAGPVFLVDRTAHASIQVLRGIFE
                     QIGPVSRFDAHDTAGLGALLDEAVDAGRTPIVLVDGIGSMGGLIDVVELNALTAAAGGY
                     LYVDDAHGISIAGPQGGGYAHEAFGTDLPDSVILVGSLSKAFGGAGGFGVLRDRADTKV
                     LRKFGNPLIFGGPIALPMVSANLASARLHLNGAVVPLQDRLWQNTELFDQHTYGRLVNA
                     GERSPVRGAAFAAEADALAAAERLRKAGILVTPAFYPTVARGTGLVRFAVSALHTDEQI
                     ARAAEALGDLD"
     aSDomain        complement(24595..25638)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GR130_RS21735_Aminotran_1_2.1"
                     /evalue="6.00E-23"
                     /label="GR130_RS21735_Aminotran_1_2.1"
                     /locus_tag="GR130_RS21735"
                     /protein_end="406"
                     /protein_start="58"
                     /score="73.5"
                     /tool="antismash"
                     /translation="YLGLEVHPQLLHSAKEAIDRAGVHFASARTRMRLDDLEELESILD
                     RIYGLRSVTAFTSVGNVHLGVLPLLAADALPSYPMAEAGPVFLVDRTAHASIQVLRGIF
                     EQIGPVSRFDAHDTAGLGALLDEAVDAGRTPIVLVDGIGSMGGLIDVVELNALTAAAGG
                     YLYVDDAHGISIAGPQGGGYAHEAFGTDLPDSVILVGSLSKAFGGAGGFGVLRDRADTK
                     VLRKFGNPLIFGGPIALPMVSANLASARLHLNGAVVPLQDRLWQNTELFDQHTYGRLVN
                     AGERSPVRGAAFAAEADALAAAERLRKAGILVTPAFYPTVARGTGLVRFAVSALHTDEQ
                     IARAAEAL"
     gene            complement(25885..27093)
                     /locus_tag="GR130_RS21740"
                     /old_locus_tag="GR130_21740"
     CDS             complement(25885..27093)
                     /NRPS_PKS="Domain: AMP-binding (49-252). E-value: 2.5e-12.
                     Score: 38.0. Matches aSDomain:
                     nrpspksdomains_GR130_RS21740_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012711.4"
                     /locus_tag="GR130_RS21740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_21740"
                     /product="AMP-binding protein"
                     /protein_id="WP_159506247.1"
                     /sec_met_domain="AMP-binding (E-value: 2e-09, bitscore:
                     35.4, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRPAAAARWPGIEGVRTADDLSELPLMSPDTLEDLCPPAVTDLV
                     LDSADSGMVLRSSGTSGKRKVLYHSWEFDVRVTHLGARGVRAALTTAPSRVGNCLYPGE
                     LNGAFSFAQDLTRRLGAQTYPLGTSMRTEELLEVIREHRIDTLIGSPAMGADLLSDPAN
                     LASLASLRTYLYIGENLGAARAAVMTEAIPGLRVRSLSYSTSETGPIGYQCPFQGDGTH
                     HVHDDAMFVEVVDPETGAEVADGEEGEVITTTLTDTGMPLVRFRMGDRAIRHTTGGCAC
                     GSPTSRITLTGRVPRSLNVDGATISQDLVMAQLRGLGVADPADCQFQVRRAPDRGFDVV
                     LLLADRLAVRPTGDEVLRRLREGYHLGRVFAMPGFRGFTLRHVPTADFVRNTRGKTPFF
                     VEL"
     aSDomain        complement(26338..26946)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GR130_RS21740_AMP-binding.1"
                     /evalue="2.50E-12"
                     /label="GR130_RS21740_AMP-binding.1"
                     /locus_tag="GR130_RS21740"
                     /protein_end="252"
                     /protein_start="49"
                     /score="38.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DSGMVLRSSGTSGKRKVLYHSWEFDVRVTHLGARGVRAALTTAPS
                     RVGNCLYPGELNGAFSFAQDLTRRLGAQTYPLGTSMRTEELLEVIREHRIDTLIGSPAM
                     GADLLSDPANLASLASLRTYLYIGENLGAARAAVMTEAIPGLRVRSLSYSTSETGPIGY
                     QCPFQGDGTHHVHDDAMFVEVVDPETGAEVADGEEGEVIT"
     misc_feature    complement(27384..27398)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.41"
                     /tool="antismash"
     gene            28360..28965
                     /locus_tag="GR130_RS21745"
                     /old_locus_tag="GR130_21745"
     CDS             28360..28965
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018541084.1"
                     /locus_tag="GR130_RS21745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_21745"
                     /product="hypothetical protein"
                     /protein_id="WP_159506248.1"
                     /transl_table=11
                     /translation="MNTATTRFRGRAGRRLAATVVATAALGLGATACGQGSGTTGAAGP
                     SASAQPTSGSPSDKSNSQGHNGGKSTAAPSAARGSGTGGSTGGKPASTGGGVAHAGNHR
                     TIVGTLNYLAPGKLIVKPQGGGTDQAFLISNATRILGAAAICSDSDGSVTIGRDGYGTS
                     KCTVNQLETAAKTNSVTVRVTMNPKSGGAETVEEKYHP"
     gene            28931..29137
                     /locus_tag="GR130_RS21750"
                     /old_locus_tag="GR130_21750"
     CDS             28931..29137
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GR130_RS21750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GR130_21750"
                     /product="hypothetical protein"
                     /protein_id="WP_159506249.1"
                     /transl_table=11
                     /translation="MPRRSRRSTTRKPRHPFAAATTRSTNVYANVLCPDPSALFTYLTT
                     RVAALPSIQHMETAAVTQTIKTL"
     gene            complement(29671..30240)
                     /locus_tag="GR130_RS21755"
                     /old_locus_tag="GR130_21755"
     CDS             complement(29671..30240)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572593.1"
                     /locus_tag="GR130_RS21755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_21755"
                     /product="hypothetical protein"
                     /protein_id="WP_159506250.1"
                     /transl_table=11
                     /translation="MRKLQKAAVVAAVLGSFGFVGAGTAYAHGEKEGGRGGTDFEVRQG
                     SQCRSHDTNVDVLGEVGILNGVLGNALGGEGSPGAQSTRMGSSMGCDNSVDFMGDKGGG
                     EGRSGGSEGREGRGDKRGDEGKAGGSEGREGKGDEGDKGDRGDKGGDEGKSGGSEGREG
                     KGGKEAGEAKEGGEGPVRAVGGGAGE"
     misc_feature    complement(30305..30318)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.73"
                     /tool="antismash"
     misc_feature    complement(30842..30857)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.27"
                     /tool="antismash"
     misc_feature    complement(31079..31094)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.52"
                     /tool="antismash"
     gene            31799..33949
                     /gene="helR"
                     /locus_tag="GR130_RS21760"
                     /old_locus_tag="GR130_21760"
     CDS             31799..33949
                     /codon_start=1
                     /gene="helR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018539646.1"
                     /locus_tag="GR130_RS21760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_21760"
                     /product="RNA polymerase recycling motor ATPase HelR"
                     /protein_id="WP_159506251.1"
                     /transl_table=11
                     /translation="MNPLSTSVFDLPDRLSPKADPTLIAGDELHFAAIAESLEQSIAEL
                     SDRLDAELRAPGGIGRQAMDRDAEVQRLTGRLRALRRFGWDLCLGRVVGADDPEPVYIG
                     RLGLTDSTGRRLLVDWRSPAAASFFAATHANPMGLASRRRYRWTSGRISDYWDEVFTAD
                     GLDGHSALDDQSAFIASLGSTRSSRMRDVLATIQADQDAIIRAGSRGALVVDGGPGTGK
                     TVVALHRTAHLLYSDPRLGHRHGGVLFVGPHQPYLAYVEDVLPSLGEEGVQTCTVRDLV
                     AEGAGAAVEADPDVALLKSSADMVKAIEAAVRFYEEPPAEGMTVTTDWADIWLSADDWA
                     EAFDAPDPSTEHNEAREQIWEELVTILLDKLDGDVSPDVFHSSLRHDEELVTALNRAWP
                     LLEATDLVGDLWSVPAYLRLCAPWLSRDEVRRLQRKEAPQAWTVSDLPLLDAARQRLGD
                     PEAARRKRRQEAAVAAERARMADVIDNVLAADDDGEGAVTMLRGQDLRDRLIDRTAVPG
                     ADPDRLAGPFAHIVVDEAQELTDAEWQMLLLRCPSRSFTIVGDRAQARRGFTESWQERL
                     KRIGLDRIEVASLSVNYRTPEEVMAEAEPFIRAELPDANVPTSIRSGGVPVTYGSVADR
                     ESILGAWLAAHADGIACVIGDPTFQATSRVRSLTPELSKGLEFDLVVVVDPEEFGKGIE
                     GAVDRYVAMTRATRQLVILTSS"
     gene            complement(34478..35110)
                     /locus_tag="GR130_RS21765"
                     /old_locus_tag="GR130_21765"
     CDS             complement(34478..35110)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003995281.1"
                     /locus_tag="GR130_RS21765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_21765"
                     /product="TetR-like C-terminal domain-containing protein"
                     /protein_id="WP_159510126.1"
                     /transl_table=11
                     /translation="MGRPRTNDETVKERLVECATELLATGPRESVTVRAVAAAAGASTT
                     AVYSLFGGKDGLIGAVRDRAVASLFQDLSAVPTSQDPLADMYALAVAYRRWGCGHRHLY
                     MVLFGGVQSFEPSGAVGARDPIRPLIAAIDRGVEGSVLAGEVTSIALSLWVTLHGLVTL
                     ELAGGFDAHTAEAAFRSTIHAMLRGWATPAVFRSLRQAELGSPGQRL"
     misc_feature    35076..35091
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.98"
                     /tool="antismash"
     gene            35178..36512
                     /locus_tag="GR130_RS21770"
                     /old_locus_tag="GR130_21770"
     CDS             35178..36512
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (133-222). E-value:
                     2.7e-12. Score: 38.8. Matches aSDomain:
                     nrpspksdomains_GR130_RS21770_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003995280.1"
                     /locus_tag="GR130_RS21770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_21770"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_159506252.1"
                     /sec_met_domain="PF00561 (E-value: 9.9e-08, bitscore: 30.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 4.6e-10, bitscore:
                     39.3, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTFALRLVRFAGRLLLALTAVTTLVVVFLVLIVLTDGAGSGLAA
                     WLTTLGLASAAALWRGRGRTRAARLVPFLPVVVAAALTASVCIPTVPTTRRYPPALPFV
                     ATQHWKLATGSQVAVYHYPPAAPRTRHPIPLVYLNGGPVRGISVLDHRFLQLLARQGYD
                     VYAYEQAGGGRSDLLSMDQYTISRSVRDLDAFTRRLDRGKVDVLGFSSGAVVVTRALAA
                     PSVAAHLHRAIIAEPGPMDGSTSRITGHQGRPSARGLAPGMTGPRSTQLPRYAVAFGLM
                     RLGLLTPDTGLIGQAEGDNAFTAADLGSDTASAYCARDAHRIPTEDTAQNFSFSSAPSL
                     HIQQTVKDSPSSAPQLRRSKTPAMLMIAECSSQVRQWETTILANDPAVQRTQYMPEVGH
                     HMWNGLDDNNDRAAAVITSFLQGKPAPLPNYPTRDEIPAFLRDHK"
     misc_feature    35220..35222
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        35577..35843
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GR130_RS21770_Abhydrolase_1.1"
                     /evalue="2.70E-12"
                     /label="GR130_RS21770_Abhydrolase_1.1"
                     /locus_tag="GR130_RS21770"
                     /protein_end="222"
                     /protein_start="133"
                     /score="38.8"
                     /tool="antismash"
                     /translation="PLVYLNGGPVRGISVLDHRFLQLLARQGYDVYAYEQAGGGRSDLL
                     SMDQYTISRSVRDLDAFTRRLDRGKVDVLGFSSGAVVVTRALAA"
     gene            37347..37493
                     /locus_tag="GR130_RS21775"
                     /old_locus_tag="GR130_21775"
     CDS             37347..37493
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GR130_RS21775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GR130_21775"
                     /product="hypothetical protein"
                     /protein_id="WP_159506253.1"
                     /transl_table=11
                     /translation="MTSTATGRNGATQVTVRAARTGLVTVTWGPDDTPVFALRLNVAGY
                     PVQ"
     gene            complement(37570..40245)
                     /locus_tag="GR130_RS21780"
                     /old_locus_tag="GR130_21780"
     CDS             complement(37570..40245)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018541879.1"
                     /locus_tag="GR130_RS21780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_21780"
                     /product="glycosyl hydrolase"
                     /protein_id="WP_159506254.1"
                     /transl_table=11
                     /translation="MVPQRHRRRFITCAAVAAAFGLATTQSFAASGESRPRPWNARHQA
                     DIGRQHIKAAHAGRGKSAAATPGGSEGDSDEAENSAEATAQFTEARTAPGVVAPGAYGA
                     AWQQLQSMRHTPGDWDHVTKKAYNADDPRYRDVNSNSSGGFGKVTGRITGIAADDQGYV
                     YAGGANGGVFRSKTGGGRWEPIADKLPSLSTGTLALDGKKRLWYATGESNTGATAFVGT
                     GVYVLGDPRHGQFRPGNRVGGAELESTVIHALRFVGGTVWAATSRGVWSHSTTTLSGPW
                     KLEFAPNPDYLPDGSKASDPSAPYKNIANDIAVDPKDPSKVLLAVGWRGGDTYNGLYAK
                     QDGGWKPVSGLGDLPTGSADVGNMTFAAAADGSRLYAIDQSPAQTTANPDSGLKGVYVS
                     KNGSPFGPWTQVADYTKLKASGSALQSAGYQPGIQSWYNQFLQVDPANADHVYLGLEEV
                     FETKNGGTSWTTPGPYWNFPFPCWSIDPAKQTGDCSQTTHSDQHAVAIGSYHGKTWAYV
                     GNDGGIYRRPLNGAVDSGGHAKDWQSLNDGTLDTLQYYSVGVGKDLAHGGVSVTGGLQD
                     NGQSILRGRDKVMGSNFGGDGADTIADPANGCNIAAEYVYLDMWVTQNCGVNDGSWNTD
                     PTKATEYEVAPPDKDLGGAGARFIAPITADTKDGNTWVAGGRHVWVQNKGFAIRSRTEW
                     KNAYDLGDGHVATAVTSSGGTVYAGWCGPCDSKGFSRGIAVGNADGTGWHQLTLPVDGT
                     LPNRYLSGFEVDPANARHVYVAVNGFSRKWTEGPGAGVGHVFESKNGGTDWTDISANLP
                     DVPANTVKLLPNGGLALGTDLATFYRPAGATRWQVAGHDLPTAAVMQLRLGPDGKLYAA
                     THGRGIWSLDVRRLVATRND"
     misc_feature    complement(40348..40359)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.55"
                     /tool="antismash"
ORIGIN
        1 cgaaaacgcc cgcctgttct gccagatccg cgacagcgcc gaaaccttcc aacgcctgct
       61 cctgccgacc ctcccagact tgcggccctt caccgctgcc gcgatctacc ggcccgccgc
      121 tgaacccaac cgattaggcg gggactggta cgacgccgtc atcctgcccg acggagccgt
      181 cggtgtcgtc atcggagacg tcgtcggcca cgacctgcac gccgccgccg caatggctca
      241 gacccgcagc atgctccgag ccctgctcta cgaccaccgc actccaccca acaacatcct
      301 cacccagctc gaccacaccc tgcacgccac cacccccaac cccatcacca ccgcactgct
      361 ggcccgcatc gaaccccggg accacggctg gtcgctgcac tggagcaccg ccggacacct
      421 ccccccactg ctgatcaccc ccgatcggcg ggccgaatac ctccgcgccg accccggcgt
      481 cccactcgga atcaacgccg cccacagccg ccccgaccac agccgcccgc tccccgcaga
      541 cgcaacgctg atcttcttca ccgacggact catcgaacac cccgcccacg ccatcgacga
      601 ggggctggac gccctggccg cactggccac cacgcatgcg gaccagccac tgcaggactt
      661 ggtgcggacc ctcgccgacc accaccccag caacggccag gacgacatgg ccatcctcgc
      721 cctacgcacc ccacccgcca cctgacctcg ccgcacaagg cgcgccacac gacgccacgc
      781 gatcccgcgt tcgccgcgga cgggcggaac ggctgccggc ggcggtatca gccgggtgac
      841 gtcgttgcga tcgccgccgg tcaacgtaac ggccaggggg atgccgttgg catcgcagac
      901 cacgcggtgc ggggagcccg gccggcttcg gggtggcgtg aacgaggggc gggaaagctg
      961 acgtaggagg gcgtgcccgc gccagcggct cacggtgcac accggcgctc acgtcccctc
     1021 aagcgctcca gcgcgagccc ggggtagacg tcgcccgtgc gccgcgcggc gtacggaagc
     1081 gtggtcggcg tgcgcctgca tgcgacgtgc ccctgtcata tgcaagatgg cttgactgtg
     1141 ccgtgtcgac tctgtgcgcc ctgggccagg agttgccggg gcgggctgcg gcgagtgttg
     1201 tagacggcgg aactactagc tggcctgaaa gacccgttgc cgattcggca acgtacggca
     1261 gctgcggcgg gcacgcaccg aacggtgcgg actcccaagc ggcgccgggg cctgcctggt
     1321 cgccgtgccg gtgccgtggt gctccgcggc cgggccgctg cggcccggcg tcggtggggg
     1381 tgcgctggct gggcggaggg ggctgccgtg cccacctcca tgcgtgcggt gccgaccggg
     1441 ctgtcgtgcg tttccggacc gggcccgggc tgtggtcacc gctgccaggg gcgccgcggc
     1501 gggtatggcg gtgcgtccgg cgccggccat gggcctgcga cctcaaggga agtccgcgga
     1561 tagcaaagca gcgacaacgg agtgccaagt gacgtcgaat gaaacggtcc gggacctgcg
     1621 cgctacgcat caggctcggg cggacatatc ggatccggag gcttgtgggc cggcccaggg
     1681 gagggtctcg ggaatctgcc cgaagacctg cgggcccggt tcgcgcaagc cccagcggtt
     1741 gaaggcggtg gctccgacgg agcggtgtgt cacatcatga gcgagcccag cgtgtccttc
     1801 gcatcgcggg agccgttgtc ggtctccggc tggctggtga acgcattacg cgcccaagga
     1861 gtggagtacg tattcgctgt ccccggtggg ccgctgctgt cgttgtacga ggagcttgcg
     1921 aactcaccag gggtgaggct ggtcctgacc cggcatgagg aagccgcggc cttcatggcg
     1981 gacgggtacg cccaggcgag cgggcggttg gcggtcgtgt gtgcgacgac agggccgggc
     2041 gcgatgcaca ccctcaccgg tgtcgccagc gcgacaagcg actcgatgcc gctggtggtg
     2101 atcaccgcgc agaccgcggc ttcggcgttc ggccgtagcg gactgcagga cagcagcggc
     2161 gggaactggt cggtcgacac cgtggagatg ttgcgaaccg cgaccaagct gtcgacccgg
     2221 ctcgcccatc ccggccagtt gccgtggctg ttctgccaca tgatgcggac catctggaac
     2281 gggcgtcccg gcgcggtcca tctgagcctg agttccgaca tgatgagcag ccccgtgccg
     2341 gacgtttcca taccctcgcc ctgccacgcg gcgtccaccg tgcctgatgc ggctgcggtg
     2401 gcggtgctcg cgcaggaact tcgacggtcg cggcggccgg tgatccttgc cgggcagggc
     2461 gcgaagttgt ccggcgcggc cggctcgctg caacagctcg cccagaccgc gggcataccg
     2521 gtcgcgacca cactgaaggg caagggcgtc ttccctgaag accacgcgtg ggcgctgggc
     2581 gtgttcgggc tcggcggcaa ccctgccgcg ttcgactatc tgctctcccc cgaagtcgac
     2641 ctgctgctga tcgtcggcag tgggctgggc gaggcggccg ccaacgcctt cgactcccgc
     2701 ctggtgacgg gacgtcaggt catccagatc gacctcgacc cgctgcgtct gggtgccggc
     2761 tgcgatctcg acctggccgt cgccggcgac gccgacaccg tgctgcgcgc actgcttgcc
     2821 gaactggagg atgcgcccgc cgcaccatgt gtccccgacg ccgtgctcag cgcggcacag
     2881 gaccagctcc tggtgcgtgt tccggcgtcc gccatacaga aggaccacaa ggtcctgtcc
     2941 gcgtcggccg tggtgagcag gatgagcgag cagctgcctg aggacaccat cctctacgtc
     3001 gacaacggca actgcctgag ctgggtcggc cagcactacc ggtcccggcc cgacgggcag
     3061 atccacttct ccttcaacgt cgcgtccatg gggtacagca ccggggccgc catcggcggc
     3121 cagctcgccc acccgggacg taccgtcgta gcggtcaccg gcgatgcggc attcgcgatg
     3181 agcgggatgg aactgcacac tgccgccgaa ctcggtctcc ccgtcatctg ggtcgtcctc
     3241 aacaacggcg gcaacgccat ggtcctcaac atccaggaga gcatctacgg ccacggatcc
     3301 cgctcgatgt acgactgccc catcgacgca gcagccatcg cccgaggact cggcgcccaa
     3361 gcccgcaccg cagcggacct ggactctttc acccaagccc tcggcgaggc cctggaagcc
     3421 gacagcccct tcctcatcga cgttcacgtg gacccctccg aggtcccctg ggcactcggc
     3481 acccgcgtca ccagcctgcg gtcggccctc accgaccgcc gcgcaggcag gtggtgaccg
     3541 cggtgcgcct gccctaccca cgccccgagg accaccccga gccgctgaag gaggtgccgc
     3601 cgctcaatct gttccgcgcc ttcggcaatg cccccgccta caccggcggc ctcatcgacc
     3661 tcggcctcgt cggcctcggc aagctcgtcc tcaccccacg gcaacgtgaa ctgctgatcc
     3721 tcgataccgc gaccagcacc ggatccgcct acgtgaccca ggctcatgtc ccgttcgggc
     3781 aagccgtggg catcaccggc gagcaagcgt ccttcattcg gcagcgggaa ccactgccgg
     3841 gccccttcct cccagaagaa gccgcgctcc tggccgtggg ccgtgaactc ctccagagcg
     3901 ccacctgcac gggcgaggcc atccagcgtg cacacctgct ctgcggcgcc cgagcagtca
     3961 ccgagaccct catcctggtc ggctactacc gtcttgtctg cggcttcgcc aacgccctgg
     4021 acgtggagcc ggacggcaag tccacccaca tgctccccta cgcctcctga cccctacgca
     4081 ggtctgctca cgggcatcac agcccgggga caccgctcgt ccccgtacgc cggcgggcgg
     4141 acctgcgacc ctggttccgg ccggaccggt gggccgcgac cgtaggcccg ccgggcggtg
     4201 gtgggcctgt caggagggcg cgccggctcc atcaccaggg cgtcccgctg ggacctccac
     4261 cgtcggagac accgggcgaa acacccgctc acccctctgg ggcctcgagg ccccggtgtc
     4321 ctcctggatg tgcgggatgg cgatgccgac gacggtcacg tccaccgcgt ccatgaaggt
     4381 cgccacgagg aggacgatca gcgcccccca ccggagggga tccaccgccg tcggcaaggg
     4441 agcgaccggc gcatcggcaa tccgacgact ccgccgagga tcaccgggat ctgccggaga
     4501 agcctgggtc cgtgcttctc agaccgccgc ggccctcgga ctgcgtgacg tgtcactgcc
     4561 gggcaccggc tcggaggcgt cggcaccgag ggccacgatg cggttgtccc cgtcgacgtg
     4621 cacgaccttc ggccgcagcg tacgggcctc cgcgtcgtcc acctgcgcat agctgatcag
     4681 gatgaccaga tcaccgggat gaaccaggtg tgcggcggct ccgttgatac cgatgacgcc
     4741 cgagccccgc tcgccctcga tgacgtacgt ctccagccgg gcaccgttgt cgatgtcgac
     4801 gatgtggacg agttcgccag gcagcaggtc ggcggcctcc atcagcccag cgtcgatcgt
     4861 gaccgacccc acgtagtgca gatcggcctc ggtcacggtg gcccggtgga tcttggactt
     4921 gaacatggtg cgcagcacag cgtcacactc ctgccgaaga aaggtcgcgc cctcaccgcg
     4981 aggtgcgcgc cggacaagcc atgctagccg cgacgtcctg gacgtgtccc aggcattcca
     5041 ggcaccaccg ccactgcgct actctccgtc actcgcgcat tccgaacgta aggtgcccgg
     5101 cgttctgtcg cggctgccgc cgatctccgg aaccaacggg aagcgggacg tccgacgtct
     5161 tcggagtacc cgagccgaag ccctcacggt ggggccgggc ctcctgctcc accgccgcct
     5221 gtggggtgtt cgccgaaccg ggcatcggct tcgttcggcg gcggccggtg gggcccgtct
     5281 gcggccggga ggtcgcacat cacctcccgg ccgcagggct cttcccggcg gcggggactg
     5341 tcgcgccgcc gcgctgtcac cggccgttca gcacgccggt tcccggggcc gcctaaccga
     5401 acgcacggcg ggccgcgcga cgccagcggt tggcggggag agcggggtgc agtgcggcga
     5461 aggctccgca gtacttggtg aagacggcgg ggcgtatccc gtgggcgtgc agcaggaggt
     5521 cggcctcggt gagatgcccg gtggtcttgg tctcgacgag cacgaggtcg tccgcgcacc
     5581 gcacggtgtg tccggtgcgc aggtcgtcgc agaccagtgc cgcgtcgcag gtgatgcgct
     5641 cgccgtcggc cacgaaggtg gcgcggatgt agtcggtgct cagggacggt tcgaggacgg
     5701 ccggggcacc gatgccgtac gcggtccgca gggtttcggc gaggaacccc cggcagtccg
     5761 ggtcgagcgg cgtgccggct ccggtcagcg ggcgacggcg tttgacggtg tcgccgcgcg
     5821 gccccttgag cttgatctcg aactgccgct cccccgtgtc cgcgtagacc cgttcccgga
     5881 tcttgaagcg gagccggcgg ccctgccggt ggtcgtggaa ggagcggagt tcgggagtgt
     5941 cgtagtagac ggagtggtag cggaaggcac gccggtcgtc gatggcgagg gcgcggaagg
     6001 ggcgcccgcc gggccggcgc gggtctgtca gccggccgac gatgcgcagg aaggtgtccg
     6061 cgggcacgag atagctgtgg tcgaagcggg cgaggagggc ggcccgttcg ttgagttcgt
     6121 cgagcgagat ggggccggcg ccgtcggcgg cgtcgccgat ggcgcggacc gcggctgcgg
     6181 agcggaccgg tgcggtggtc ataccgtctc ccaggcgggc gtggtccggg gggcgggtcc
     6241 ggcggcgggg acggtgcccc gctcggccgg cgccgccgcg ggctcgcggt agcggacgtc
     6301 gacgacggtg aggtcccgga cgaagtccac ttccatgacg gtccagtgga ggggttcgcc
     6361 cagtcgccgg gcgaggtcgg cgcggagggc ggcggggtcc tcgtggacgg tgtcgagggt
     6421 gacgactgcg cgccgagtgc cggcgaggag gcgggggttg tcagccgccc agacaatgag
     6481 gagcagggcg gcgcacagtc cggcggtgag gacgaacggc agcctcggca gtccgcagag
     6541 caagccgagg accaaggtgg tgaagtagta ggcgacttct tcgtgctgca cggcgtcgga
     6601 gcggagtctg acgatcgaga gcacgccgaa gagaccgaag cccagggccg ctcccccggc
     6661 gccgcgcact tcggcgaggg cggtgacgac cgtgaagagg ccggtgttca gggcgagata
     6721 ggccggtacg aggtcacgcc ggcggtgccg cggatagtag atggcgaagg tcagcacgcc
     6781 gacggcggcg aggtcgagcc cgaggtgggc gatgaggtgc cgtaacgatt ccatggctgt
     6841 gctccctgtc ggtgcggaga tcggacggat ccgagagaac gggaaggaga gacagacgat
     6901 aggtaaacgt atggcgaaca tgcttccgct tgtggagaaa cgatgcgcct ccttgatggc
     6961 ccacggccgt aactgacctg aagcacacac ctcctgtcgc attcgccgct cttgccagcc
     7021 gcctccggcg ccgccctggg cgcgggaggc cgacgagggt gcggtgtccg aggtcagcgc
     7081 cgcggactcc gtccaccgag gccgggcgga cccacccgcc ggcggcgtgt gcgccttcgg
     7141 cgcgtacgag ccccgccacc gcgcgggctg gtgacccggc cggggcgctc ccacccaggc
     7201 tcggacaccg cggtcagcgc gtcgatggcg tccgtcgctc tgggtgtcac gcgggctgct
     7261 cggtgccact gactaccggt aagctgagcc ggatcgcgtg aggtggtcgc ccgctggcac
     7321 gctgcacgca tgcatcacac agaggtactg ctcatcggag gacgtgctgg tgtcggcaag
     7381 acgacggtgg ggtgggaggt ttcggcgctg ctgcgctccg agtcggtcgc tcacgcgatc
     7441 atcgatggtg acttcatggg gcaggtacat ccggcaccag agggagaccc tcaccgcgcg
     7501 gaggtcaccg agagcaatct gactgccgtg tgggcgaact tcgcccagcg cggctaccga
     7561 cgcctgatct atacgaacac cacgagtgtg ctcccggagg cgacgggcat gttcgagcgt
     7621 gccatggggg ccggagtggg gatcacacga gtcctgctca ccgcctccga cgccaccgcc
     7681 cgcacgcggc tggtgggacg agaactcggc tcggagctgg agcaggagct ggagggaagc
     7741 atccgcaagg cacggctcct ggaccagcgg gccctcggag agaccgtgcg agtggcgacg
     7801 gacggacggc tcgtcgttga catcgcgcgg gaggtagtgg ccgccaccgg ttgggccggg
     7861 cctcacgtca cccgcagatc atgatcccgc tcgtcggcag gacacgttcg agtacctgat
     7921 gggccgcatc gcgtcgcggt tcgcgcgggt ggaaccgcgg tgccgggcag gggagttcgc
     7981 gcttggcccg ttgtcggacc tgccgcgccg gaactgctgg acgctcgccg agcaggcaag
     8041 gaacgcgccc ccggacggct tgcagcgtct gctgtcggtg accagttcct gacgcgaaga
     8101 agccccgcag ctccggcccg gagctgcggg gccctgctcg gccctcgctt gtctgctagg
     8161 ggtgcagctc gacccagtcg acgaccgtgt tgcccggtac gttggtgtag tcgtcgcact
     8221 ggtcagccgc gtgctggagc ttgcgctggt gcggctctcc ggggttgggg gcccaggcgt
     8281 agaccgccca gccggagtag acgcagacct gactgacgcc tgtgatgggg ccgatgtcgt
     8341 agctgcctgc gtcgttgtag cagtacttgt tgccgggggt gaagacggca aaggcgcagt
     8401 ccgacgcggc tgcggccttc ttggtgacgc ggaccccgtc gtcagccgag gccgaggagg
     8461 aggtcatccc caggaaaccg aggctcgcgg cgaggacgga tgcggtggcg acgattcttc
     8521 gcggtgtatt caccgtgctc cttcagatgc gggccgtcgg cggcgtcccc tccgacggcg
     8581 gatcggaata cgaggaagac gcgtcggccg cgtgacgacc tcgcggcgct tcaacagacc
     8641 ttcccccgtt gcgggttgac cgcagtgcgg cactccgcgc gccccctggg aagcggggca
     8701 tgcatgatgc tgccgtccgt cccgcgccgc cgacaggacg tccagcggac gtttagcgga
     8761 cgttctcccg ggtcggccac agtgcctcat cggaagtgaa gccgtgtggc cgggggccgc
     8821 gcggtccggg cccgcggggc gaggagaggg catgccggaa cggttcgaca cagtgctgcg
     8881 cgcctacaga cggcgggccg ggctgaccca ggaggagctg tcggagcggg cggggctgtc
     8941 ggcccggacc atccgcgcgc tggagtccgg gcagggacgg gtgccccgca tggcctcggt
     9001 gcgggaggtc gcgaaggcac tcgggttggg ggcggacgac cagcggcgcc tgctcgccgc
     9061 ggccgacgag cgggaggggg cggcggggtc cgtgtccctg gggcgccgac ggtatctgcc
     9121 ttatgacata ccggacttca cggggcgcac cgccgaggtg gcccggctcg cggagctcgt
     9181 cggcggcggc accgcgagcg cggtggtggt gtcggcgatc gacggcatgg cgggcgtcgg
     9241 caagaccacg ctggcggtgc acgccgccca tctcctggcc gacgggttcc cggacggcca
     9301 gttctactgc gacctccacg gcttcacccc ggggtacgac ccggtgggcc cggcttcggc
     9361 gctggaggcg ctgctgcgca tggccggtgt cgacggcgca cgcatcccgc acaccctgga
     9421 ggagcggtcg gccctgtggc gtaccacgct gtcggactgg cgggcgctga tggtgctgga
     9481 caacgccgcc gacgcggcgc aggtgcgtcc gctgctgccc ggctccgcct cgtgcgcggt
     9541 gctggtgacc tcgcggcggc ggctcctggc actggagggt gccgtcccgc tctcgctcgg
     9601 tgtgctgtcc gaggcggagg cgtgcgcgct ggtggcccgg atcgcgggac acgaccgggt
     9661 cgccgacgcg cccgaggccg tcgccgagat cgccgagctg tgcggctacc tgccgctggc
     9721 catccggatg gcagcggccc ggctcgccca ccggcccgcg tggacagcgg aagatctcac
     9781 cgccgagctc cgcaggggcc gccgccggtc cggccccggc ggcaacgatc aggcggtcag
     9841 cgcggccttc gccctgtcct atgcacgcct gagcccgggc cgtcagcggc tgttccggct
     9901 gctcggcctg caccccggcg ccgatctcga cgcgtacgcg gccgcggccc tggcgggtac
     9961 ggacgcggtg acggcacggc agtggctgga ggaactcgtc gacgtacacc tgctggagca
    10021 gtacgaaccc catcgctacc aactacacga tctgctccgc cgacacaccc aggaggtcct
    10081 gcacgagacc gagccccccg cacagcggga agaggcggaa ctccggctcc tcgaccacta
    10141 cctgcacacc gcgctgcacg cccgccccct ggtggcaccg ggacagcggc tgctcccctt
    10201 cgaggtcgcc cgcccaccgg ccgacacccc ggacgtgagc gaccgggcct cggccctggc
    10261 ctggtacgag gccgagcacg ccaacctcgt cgcgatgatc acgcatgccg ccgcgcgggg
    10321 caggaacgag catgtctggc agtacaccca tctcctccag catttcttcg acatccgggg
    10381 gcgcaccctg gactgggtca gcacccacga actcgccctg gccaccactg gggacctcga
    10441 caaccgcctg gcccacgccg agatcctgac cagcctcggc gtcgcctgct ggcacgccgg
    10501 gcgctacgag gacgccttca accgggggct ggaggcgctg gccctgtgcc gggagatcgg
    10561 cgacgcatgg ggcgaggccg tcatcctcac caacttcggc atcgtccaag ggcagttggg
    10621 gcagagcgag gaggccatcg accttcacca gcaggccctg gccctctacg gcggcgtcga
    10681 cgccccctgg ggcgaggccc tgagcctgac cagcctggga acggtctacg cccggctcgg
    10741 gcgggcagcg gaggctctcg accaccaccg gcgggcgctc gaccgctacc gggggatcgg
    10801 tgacccgtgg ggcgaggccc tcaccctcac gaacatgggc accggttacc ggcagttggg
    10861 acagttcggg gaggccgtcg accaccacgc acaggcgctc tccctcagcc gccggatggg
    10921 cgaccggcgc gccgagagcg agatcctcaa cgacctcggt gccacctacc acgcggccgg
    10981 ccgccgcgac gccgcccgcc gtcgacacct gcgggcgctg gacatcgccc gcgccatcga
    11041 cagcagcccg caaatcgccc gcgcccacca gggcatcgcc tacaccctgg ccccggacga
    11101 ccccgattcc gcccgcgacc acgccgagcg ggcgctcgcg atccacggcg agctgagcgc
    11161 ccccgaaacc gccgagctca ccgcgttcct ggacgctctc ggtcagggcc cggccgcggg
    11221 gcactgatcg ccgacccgca cacgcaccag cgactgcccg cccgcccgct ctccccgcgc
    11281 agcctgccgt ccggcaggct ggtcggcgtc gagggggcgg gcaacttgca cgagcccgga
    11341 gcgccctggg ccaccatcgc gtcatcgacc tgcgtcagca cgggtcctga cgcgcgagtg
    11401 ccttcagggt cgcgttcaac cagcgcacct ctgcctggct tgtcgcacgc gcgatctgca
    11461 ggattccctg ccggaacgga tcacccaact cctcagcccc cagaggtcgt tcgccctcgt
    11521 agaagaagct gctcggctcc cggaggaagt ccagtcggcg ccgcagcacg gccgtctgct
    11581 gatccgggtc atcgagctgc cgcaggaagg ccaggacggt ggaccagtgg ttctcgtcgc
    11641 tgatctccac gccgcgggct tcccgcagtc gacgccgcag ctcgtcccgg ccctcgtcgg
    11701 tcagggtgag cacatgccgg ggagccgctc ggcttccagg ctcggtctgg cggctcagcc
    11761 aacccgcctt ctccagacgc ttgatcgccg gatacagcgt gccgtccgcg atgggacgga
    11821 catgaccggt caggtgcgca acgcaccgct tcagctcgta accgcagcgg ctacggaacg
    11881 ccctggcgca ccaggtcatc ggccgatggt ggcggccggc atcgtcggcc ggatccgtgg
    11941 ccggctcgcc gggcggacgc gtcgggaggt gggccgaggc ccgcaccgtc gaccgggccg
    12001 gccgggcggg gtccgcgcgg agaaggacct cagtcgagga gatggcgcag ataggactgc
    12061 ggggtggcga gaaagcggcg ccagtggtcg accagggcga gttcgtccca tgccacccgg
    12121 cgcataccgt gctcgccgac ctcgatgatg tccgcacccg gcagcgccgt cagcagcgga
    12181 gagtgggtgg cgcagatgac ctggcccccg ttcttcacca gctggtggag atggccgagc
    12241 agttccaggc aggaggcgaa ggagagcgcc gcctccggct cgtccatcac atacagcccc
    12301 ggctgcagga actttcctcg gaacgcggca aggaagccct ccccatggct gacggaatcc
    12361 ggcgcgaacc cttcccggcc caacgcgtcc agggcggtct cggcgcgcag gaagaacccc
    12421 ttgcgggcgg accaactgcc caacatgcgc cgcccccgcg gtgccgcgtc gaagcggatc
    12481 ctctcgccga gcaccgattt ggggcggtga ctggcatagc gccagtcgtg cgagccgccc
    12541 caggagtcca ggccgaaacc ctccgcgagg gcctcgacca aggtcgattt gcccgagccg
    12601 ttctcgccca cgagaaaggt caccggtgcg gtgaaacgca gtccgtctgc cagcagcccc
    12661 cgcacacagg gcacggacca gggccactcc tcatccttcc gcgaagccac atgagcgtac
    12721 gcacgttcga taatcatgtg gcgagtcttt cacagggcac atcgatcaag acatgccgat
    12781 accgtggcgt ggccccgctc gcacagacgg cgtgatcaac ttttccgact gcgggcgaag
    12841 gacacccact cagcctctgg gaggctcaag agccatcggg cccggaccgt cgggaagcgg
    12901 tgtgcgcggt tcgcgcactc cagcttggcc gccgtcatcg ttgccctcgt cggtgaagtc
    12961 ctccgggcgg agctcggaac gggaggaacc gtacttcaac cggcgggaca ccttcagata
    13021 cttggccacc actgacctcc gcaatacgtc tgctttgcag gcgagttggc atgcgccgcc
    13081 cgacgtccgt ctgacgtccc aggctcttgg atggttcccg cgcaccgccg cgggttcgtc
    13141 ctccggtcgc gccgccgccc ccgagcggaa gcggaagatc gtggtcagcc gccggcgccg
    13201 ccacgagtgg ctgcggccga gcgccggatg cccaacttgc cgtccatcgt tggggacttc
    13261 cgctgtgagg ccggtcaagt ctccttagaa tggggcttct cgactgttct ttcgaaaggg
    13321 acggtgccag gtgacggacg atcacctcca ggcaagaggt ctcaaccggc gacagttatt
    13381 gaaacgcgga gggcaagtag cgtccggagt gggcgcgttg tgggcgggcg acgcgctggg
    13441 ctgggcggct cccgcgcagg cgcgggacga aggtgaccgg gagccgtcgg tgacggtgtc
    13501 gtcgggcacg aatttcgccg cggcggtctc accggacggg cgatggctgg cactcgacct
    13561 gttcacggtg gtctggctgg tccccgtcgg cggaggccgg gcccgccgcc tcacggagga
    13621 cgcacaggac gcgagccggc cgagttggtc gccggacggg cagcgcctgg tcttccagtc
    13681 gttccgcgac gggtactacc agctgtggct ggtcaacacc gacggcaccg ggctgcggca
    13741 gctcaccgac gaccccgccg accaccagga gcccgccttc tccccggacg gccggcacat
    13801 cgccttcgcc tccgacgccg agaacatgaa cgccatctgg gtcatggacc tgggcgccgg
    13861 aaccagccgc cgcgtgacca ccgccaaggc ccgtgagatc acgccgacct ggtcgcctga
    13921 cggccggcgg atcgccttca cggtcggcga cacggcgatc gacgtggtcg aactcgccgg
    13981 cggcgcccgc agtacggcgg tgaccgcgcc caccggcacc accctgtgcg ggccggcctg
    14041 gaccccggac ggcacacggc tcgcctacac ccggttcacc ggccgcaccg ccgacctggt
    14101 cgtcggcgag cggaccctga cctccggcga ggacgtcttc gggttccctc ccacctggct
    14161 gtccggcacc gaactcgtct acaccgccga cggcctcatc cgacgccgca ccctcgacgg
    14221 ctccgtccgc gagatcgcgt tcacggcgac cctgcccctg gccgcgcgcg actaccgcag
    14281 acaggtgcgc gacctcacct cgcccgcgcc gcgcccggta cgcggcatcg ctagccccgt
    14341 cctgtccccc gacggccaca gcgtcgcgtt ccgggcgctg aacgcgctgt gggtgatgcc
    14401 ggtcggaggc agaccgacgg cacgggtgtc ggacgggttc ttcaacaccg accccgattt
    14461 ccacctggac ggcacgagcc tcgtctacgg cagcgaccgc tccggcaccg cgaacctgtg
    14521 gcggctgaac ctggccgatg gatcctccac ccagctcacc gacgtgcccc ggggcgcgat
    14581 gaccccgcgc tggtcgccgg acggcggccg gatcgcctac caggacgcgg acggcgccat
    14641 atgggtgctg gcggtctccg acgggtcggt gcggcaggtg ctgccggcgc tgttccagcc
    14701 ggggcggccg gcctggtcgc cggacggccg caccctcgcc gtcgccgccg tcagaccggc
    14761 gtccctgcgc aacaagtccg gcaccaacca gatcctcacc gtcgatctgg aaaccggcgc
    14821 cacgacctac gccgaacccg ccgcgcaccg ctccgtcgcc acccgcggcg acgacggccc
    14881 gctctggacg ccggacgggc ggagtctggt gttcgtcatg gaaagcacgg cctgggcgct
    14941 gcccgtggac ggcgcgggcc gcgccaccgg gccggcacgg cagctgaccc gggaggtcac
    15001 cgacgcggtc tcggtcggtg accggggccg gacgctgatg tacctgtcca acggccttct
    15061 gcgcacggtg ccgctggccg gcggcacccc gcgcaccgtg ccggtccccc tgacataccg
    15121 ggtgcacgag ggcaccgacc gactcgtact gcgggcgggc gcgctgtggg acggcgtctc
    15181 ccggcaactg cgccgtgacg tcgacgtggt gatcgagggg acgaaggtcg cgggcgtcgt
    15241 accggccggc tcggccgtcg gcggccggat cgtggacgcg tccgggctga ccgtcatgcc
    15301 ggggctgatc gacctgcaca cccactggtt catgcggggg cgcgggtggg gtgaccgcca
    15361 gggcaggctg tggctgtcgt acggcgtcac caccgcacgc tcggtcgccg acccggtcta
    15421 ccagatggtg gagacccgcg aatcgtccga ggcgggcgtc agggtcatgc cgcgtttcct
    15481 cggcaccggc gaggcgttgg acggcaaccg ggtgctgtac aacgcgatgc gcccggtgca
    15541 gtcggcggcg cagctggacc tggaactgtc ccgggccgag gcgctcgcct acgacctgct
    15601 caagtgctac atccggctcc cggtcgcgct caccgaaccg gtcgtggccc gggcccaccg
    15661 gatgggggtg ccggtcacct cgcactacgc ctacccggcc gcgcacaccg gcctggacgc
    15721 gatggagcac gtcggcggcg gcaaccgcct cggctacacc cacacggtga gccgcctggg
    15781 ccgtacctcg gacggtgtgg tcgacctgtt cgcgcgctcg ggcatgccca tcaccccgac
    15841 cctgatctac gccgccgtgc tgtacgccga ggaccggtcg ctgctggagg acccgcggac
    15901 gaaggcgctc ttcccgctct gggagtacga gttggtggag cagctggcgc ggaacgcggt
    15961 ggggcccgcg gcggacaccc tccgcttcct gctggccggc gccgtcgacc tgctcaagcg
    16021 ggtgcacgcg gccggcggcc tggtggtggc cgggaccgac gcgccgctgg acaccccggc
    16081 actggcgatg cacctgaacc tgcgggccct ggcgcagggc gggttgagca cctacgacgt
    16141 cctgcgcacg gccaccgcga actccgcgcg ggtgttgggg ctggccgacc ggctcggcac
    16201 ggtggagccg gggcgcttcg ccgatctggc cgtcgtggcg ggcgatccac tggcggacgt
    16261 caaggccgcg gcggccgtgc gcatggtcgt gaccggtgga cggctgcact cggtggacga
    16321 cctgctccgc ccgttccggc aggcggcggc cacgacggtg cggcggaacc ggatcgcagc
    16381 accgctgcgg ggcgcgcagg cggacttcag ccacgactgg caccggcccg gctgggtcga
    16441 gacgtcctgc tcctgcgcgc cgccgcgctg aacccggcgc cggtctacgg cagggcccgc
    16501 cgccctcggc gcggcgggcc ggcgacctcg cggaggaact ccgcgaaccg cccgatcccc
    16561 tcatcgatcc gatcgagcgt cagatagctg caggacaggc gaagttcgtc ggtcccaccc
    16621 ccggaaaggt agaagtgctc catcggggtc cacagcacgc cgaactccgt ggcacaccac
    16681 tccagtagag cggtatccac ccggacgggc agccgcacgc ggacgaagaa gccgccggac
    16741 gggctgttcc accgcacgcc gggaggcgtc gcaccgccca gctcgcggtc gagtgcggcc
    16801 agcagatgcg ccaggttgcg ccggtagtgc gccgaggtgg catcgcccaa cgcggccagc
    16861 gacccgccgt gcgcgagcag catcccgccg atgaccgcct ggcacagcgg cgaggtgttg
    16921 accgtgacca tgcccttgag gaccgccagg tcgtcggcga ggactccctc ggtgccgtcg
    16981 gcccgtacga ccggctggtc ggcgacggcg aacccgaccc gagcgccggg caggcacacc
    17041 ttggcgaacg tgccgaggtg gaccacccgg cagtcggtgt cgagcgcctt gagcgagggc
    17101 agggcatggc cgggcggcgc ggtgaagccg taggccgagt cctcgatcag caccaggtcg
    17161 tcgtggtcgg ccacggccag cagccgctgc cgggtctcca ggtccagcac actgcccgac
    17221 gggttggagt agtccggggc gacgtacagc gcgcgaatcc gccgtccccg cttgcgcgcc
    17281 gccgcgcagg caccgcgcag ggcgtcgagg tcgaccccgt cggcggtctc cgggaccggc
    17341 acgaggtcga cgtcgagcag ccgggcggcc cccgtcatgc cgacgtaggc gggttcgacg
    17401 accgcgagca ggtcgtcgcg cgagcggcac agcgcgcgca gggtgagcag catggcctcc
    17461 tgggcgccga cggtgaccac cacggaccgg ggcggcacgt cgatgccctg gtcgtggcgg
    17521 agcgcggcgg cgatcaggtc gttgatgagg ccgcggctcg gtccgtactc gtgcagcagg
    17581 ttccgggccc gctcggccgt cgtgccccgg tcctcgacca ggtgccgttc gtagcgcgcg
    17641 gcgtacgcgg tgacgtcgac gtcggcgagg tgggcgaggt gcggggcgcc cggggcgaag
    17701 gagatcgccg acgggtagcg cgtcatcacc tcgttgagga aggcgacgga gccgagcacc
    17761 gggttctcca ggctggcgtg caggtctccc ccggccagca cgaagccggg cgccgcactc
    17821 atggccgacc gcccgcgcgg gaccaggcgc ggtccacctt gccgatgacg tcgaggctgt
    17881 agagccgggt cgcctgtacg taggcgaact ccgccatgta ggtgcggaac agttccggag
    17941 gttcctcggc cagcgtcagc atcgcccggt tcgtcaccac ggccgggttg tcgagagccg
    18001 acaccgcctc ctcgatcgcg gtgtccatct cctccggcgc cacgacctgg tcgcacaccg
    18061 ccgcggcgcc cgggtcgccg gccgcgatcc ggtcgcccca caggatcacc cggcgggcct
    18121 ggcgggcgcc ggcgcaacgg ctcaggcgca ggttgcccgc gccgggaacg atgccctcct
    18181 gtgcggcggg aagggcgaag aacgcgccgc gctcggcgat cacgcggtcg aagaccagca
    18241 gcagttgcat gccaccgccg atggcgaacg cgtccacggc ggccacccac ggcttcccgg
    18301 cgacggcgcc gccggggtgg tgcgtcccgg caccggtgcg gtccggacgg tgcaggccgc
    18361 gctggatctt gctgatgtag cccagttcgc gctgcatcag gaagccggcg aaggagatgc
    18421 gtccctcgtg cagatgacgc agattgattc cggcgctgaa cacccgccgg cccgcgtact
    18481 tcggatgcgt catcaccccg ccgcgcagca cgccgacacg gacccggtcg tcgagcagtg
    18541 ccaggtcgac cgcggtctcc atgtccgcga tcagggtgtc gtcctcggcg ttgaggcagt
    18601 gttcgttgtg cacggtcagg tgcgcggcgg ggccccggcg ttcgacgagg accgactcca
    18661 gctcggcccg gccggtcgcg gtgaagtccg cgagcaggtc cagcgcccgc cgtgagggtg
    18721 tccgcatcgc gtcggtcaga tgggcaccgg aggcgggatc gcgcaggatc gcacgcagga
    18781 agagcccctg gtcgatctcc agtccctcct tgtgcgcctg gatgtgcttg cgctcggcgt
    18841 cgagtcgggc ctcggtgggg accaggccgg gccactgctc accggcggcg cgcaacagtt
    18901 ccgggagccg gacgtggtgg gtccggtcgc cggtcaggct gccgtacacc gcctcgacgt
    18961 gccagtccag gaaggtggcg cgcagccggc gggctgcgga caacacccgt tctgccgcgg
    19021 cctgttgggg cgcgtcgcgc tcggggcggg gcggcagggc cgcgagcgac cggtctgctg
    19081 cggcggcgta ctccgcgagg gtcgcagcgt cttcgacgag gttcccggtc aggggcggtt
    19141 cgggagcggg cccgaggtcc gcgccggtgc cggtggcggg cggggtgggc gggtgggcgt
    19201 cggcgctcac ggacgtacct cccggagttc gccggcgcgc atccgctgga gttcgcgatc
    19261 gcacgcggcc aggtgcgcgc ccagagcgtc ctcgaaggtg gcgtcatggg cctccagcag
    19321 cagccggcgc cggatggccc agtccgtccc ggacacggtg cgcagcgtcg ccagcgccgc
    19381 gtcgagcgcc gcctggggct cgtcggtgac ctcgtcgacc aggcccatgg ccagggcgcg
    19441 ttcggcggtg agtcgggcct cgcaaagtac gatgcgccgg ctccgggcga cgccgtactg
    19501 atggacgagc cggtacagcg ccatgcccgg ccagcagcgg tcgtcgttgc gcggcagcgc
    19561 gatccgcagg tcggtacggg cgatgcggac gtcggcaacc agcagcatgt ccgcggcggg
    19621 cccggcgcag ctcccctcgg ccaccgcgac gaccggcgcg tccagccgct cgacccggcg
    19681 cagcgcccgc tcccacttgt tgacctcgtg tacggcgacg ccggggcccg gccagggcgc
    19741 cgtggtggcg ggccccaggg ccagtacgag caccgcgccc gcgccggcgt cctcgacccg
    19801 ctcccgggcg gcgtcgaggt cggcgatcag cgcggggagg ggctggccgt gcgtgtgcac
    19861 ccggtggtcg gcggccggtc ccggaggtgc ctggccgtcc gtgcccacct ggtggtcggc
    19921 gcgagaatcg ttcttgcggg tcatcgtgcg tgcgtccttt cgctgcgtcg ccgtgtcggt
    19981 cctcgtggtg cccgccgcgg tcaccatcgc gccagtgccg tctcgatcgt cgatcccgga
    20041 cccatcgtca tcagcacccc gagatcgccc cgcgccaccg ttccctcggc gaccaggcgc
    20101 tcgtaggaga aaaggaagga gccgctggag aggttgccgt agtcgcgcag cacgccggtg
    20161 gtgtggcgta cgtcgtgctt ggtgaggccc aggttgaccc ggaccgagtc gatgaccttc
    20221 ttgccaccgg agtgcaccac ccagtggtcg acgtccgtcc ggcgcaggcc cgccccggcc
    20281 agcagcgcgt caacggcttc ctcggcgtgg gcgccgacca cgtagggcac gtcgcggtcg
    20341 aggaagaagc tgaacttgcc ctcgtcgtcg tcccagtcgt agcgcatggc gtcagcggcc
    20401 tcggggatga tccggctgga gaagcccgcc agcgcggggc cgctggtgtc ctggccgggc
    20461 gcgtcgccgg cctcgacgag aattgccgcg gcgccgtcgc cgaagaggct gttgacgacc
    20521 gacgtacgca tggtgccgtc gaagacgtac gccgaggagc aggactccac gcacaccatg
    20581 gcggcccgct ggcccgggtg tgcggcggcc cagccggcca cggcggtcag ggcgttgagc
    20641 ccggcgttgc agcccatccc gaccacgtcc agtcgggagc agtccacccg gagcccgagt
    20701 tcccggatca acagggcgct gaagccgggg gtgaggaagc cggtggaggt gacgcagcac
    20761 aggtagcgga tgtcggagag gccggctccc gcttccttca cgcaggtctc cagagcgcgg
    20821 gagcccatgt cgattccggt gttgacgtgc ttgcgcagca gttcgccctg cgtctcgacg
    20881 cgccgttcgc ggttcggacc gggcggcggc agggtcaggt gccgggtgtt gatcgcgctg
    20941 ttgaggaaga cggaacggat gcgctcgtcg gtgacaccga agatgtcgag gatgtcctgc
    21001 tgggtgtacg actcgggcgg caccgcggtg cccacggcgc ggatccgtgg cagcactccg
    21061 gacggtaacg tgccgttgtg cacggccggt tgggtatggg gaggtgcgag catgacggtc
    21121 atgtgttctc cggtctgtgc ggtcgggggt cagtgcgcga ggatcgcgaa accgcggtag
    21181 cgcgggatgc ggcggctggc cgcgatggcg ccggtgctct gcggtgtgct catgccgtct
    21241 cctcctctcc tggcgagaag tctggtcgga aggccgtcgg gcgggtcgcc ggcgggaagg
    21301 ggggtgtcgt gttcaccgtg ttcgcgtcat gccacctctc gggcggagac tgctcggtcg
    21361 atgccgtatc cggcggcggc gaagccggcc agcacgacca cggccaccgc catggccgac
    21421 gcggtcgccg agggcagcag gtcgtccgcg ttgcgcacga tccagccggc tgccacgttg
    21481 cccgccatct cgccgaccgc gctcatgatg gtgaccagcg acagcatcgc ggacacctgc
    21541 tccttggcca cggccttccc ggcgtcgacc tgtgactgcg gcagcgcgag acattcggcg
    21601 aaggcgaaca gcgcgaggcc gagcaggacc aggacgagcg acgaggtgaa cgacagcagc
    21661 accccggtcc cgcaggtgat cgcggccccg gcgtacaccg ccctgcggcc ggtctgggcg
    21721 aggaccggca tcatcgccag ctggatcacg atcagcgcca gcggctcgaa gctcaggaac
    21781 agctcccggt agcccgacaa ggccgggttg acctcgtcgt acagcaggaa catggccatg
    21841 atgaacccca tggcgaagta cgcgaccagc gtgtacgcca gcaccgccac cggtccgggg
    21901 cgcagcagca gcccgaggcc gcctccgacg gcgagccgtt tggccttccc ggtgtccgag
    21961 gtcagccgtc gcgcggtcgc gccggcccag gcaccgcccg ccagttccag caggagcagg
    22021 agcaccagtg cgtaccgtgc cacgtggaac cggtcggcgg cctcggcggc cagcggggcc
    22081 agcagcagcg ccacgttcat gaccacgaag aacagctgga acgccctggc ccggtccttc
    22141 tccacggtgg cgtcggtcag cagcacccgc accgcgacct tcgagacccc gcggccgaac
    22201 cccgcgagca ccgcgaagac gaacagtccc ggcggatgca ccgtggccag cagcgccacg
    22261 aaaccggccg atttcagcag tgcggagatg gacagcatcc agccgctgtt cacgccgcgg
    22321 aagaccatcg gtacgacgat gccgccgatc agcgaggcga cgacctggat ggacagggcg
    22381 agggagaacg tcagcggggc gacccgggta ccgccgaaga ccgccacggg cagcatggtc
    22441 agcacggtgg tcatgtcgat gttcgtgacg aacgtgaaca ccagcgcggc caggaccgat
    22501 ccgcggtcgc tggtctgcgt gggctgagga ggcgtcgtct cagcggcctg catggggttc
    22561 gggcctctcc ggtgcgggaa gggacagctc caccaccgac agaggggtac cggtggcggt
    22621 gacgtgggcc gggaggaacc ccgcggcggt gccgagggcg gagaagtccg ccgcggtgcg
    22681 ttcccggccc gccatcagga tcatcatcag gacgtccagg gaccgcccga cggggacgcg
    22741 gcggtcgtcg tcgagcacca tgtcgacgac cacgacgcgt ccgccgggcg ccagcgcgtc
    22801 ccggcagcgg cccaggatct gcgaggcccg ctcgtcgtcc cagtcgtgca ggacacgctt
    22861 gagaacgtgg acgtccccac cggggggcac cccgtcgaag aacgaaccgc gctccacccg
    22921 ggcgcgtccc gcggcgatca gcgcggccag cgcggggacc acctcggtct tctcccgcgg
    22981 cagttcgaac aggatgccgc gcgcccccgg gctggccgtc agcagcgccg ccagcagcga
    23041 gccgtcaccg ccgccgacat cgacgacggt ctggcccggc cgcagcggga tggccgccgc
    23101 cagtccgccg tccaggtcgc gcgaaccgtc ccgcatggtc gcgtcgaaca ggtcgctgat
    23161 ctccggtgac cgggcgagcc actcgaagaa gcgctcctga tgggtcagct cgaacgccgg
    23221 ggtgccggtg cgcagttgct ccacgagccg gtcccagctg tgccagtagc cctcctgcag
    23281 ctcgcagcgc acccagttgg cgatcccgtc cggcgcgtcc cggcacagca gccgggacgc
    23341 ctcggtgccg acgtatgcgc cggacgcgtc gagccccagg gcctcggcca ccaccaggtg
    23401 atcgaggacc ctgcgcaacg ggtcgacttc ggtccgggtc tcggcggcca gttcagcggc
    23461 ggtcatcggg cgccgtgcca gcaggtccgg gatgcccaac tcgaccgccg cgtacaggca
    23521 cttgctggtg cgataggcgg tgatctgtcc gatcagccga cgccgtaccc cgtcgccgct
    23581 caccgctccc ccaccccggt cagcatgcgg tgggcccact ggaagaaggc gtcggccacc
    23641 ttggtccgcg ccggttccgg catcagcgag aagccggcca gcgcggtgcc ccactcgccc
    23701 agcaccgggc cgttctcggt catcagccag tccacgtgca gatagccggc gtccaggctc
    23761 ccggcgatac gcaggcacat ctcccgtacg ccggcgatgt ccgggtccag ttcggcgaca
    23821 ccgccctgcc gcaggttggc ccggtaccgg cccgcggccg gacggcgcag cagcgagacc
    23881 agcacctcac cgccgaccag catcacccgc aggtcgccgg tgatcggcag gcactcctgg
    23941 accaggtagt tctggccggt ctgggcgacc acgtccaacg ccgccgacaa ctgctcgggg
    24001 gtgtccacgc gcagtaccgc cgcgcccatc cccatctccc ggggcttgac cacgtacggg
    24061 ccgtcgccga cgacctcgcg caccacaggc agtgcctggc gggcgtagcg gccgaacggc
    24121 acggccaccg tccgcggggt cggcacgtcc aggctcgccg cccgcagcat catcgccagt
    24181 ttgtcgcgct ccaggcactc ggggccccgc aacgccctgt tcagcaggac cgaatcgctg
    24241 gcatccaccg tgcgatagag agcccgcagg aagtgggcgg cctgcgggtc ggcactgacg
    24301 tcgtcgacga ggtagcagtg ccggcgcgcc agcaggtcct cgccgcggtg cagcagccgc
    24361 ggccggtcgg ccacgacggg gacgagttcg ttggccggca ggaaccggaa ggtgaatccg
    24421 ttgcgttcgg cggcggcggt gtactccttg gtcatgtccg cctcgatggc ggcggcgtag
    24481 tcgggcgtca ggtcgtcggg gtggcagatc caggtcagta cgggttcggt gggccgtcgg
    24541 gtcatgtctc ctggtttccg tacgtccatg gggtgctggt cagtcgagat ctccgagcgc
    24601 ttcggcggcg cgggcgatct gctcgtcggt gtgcagcgcg gatacggcga accgcaccag
    24661 gcccgtgcct cgggcgacgg tggggtagaa ggccggggtc accaggatcc cggccttccg
    24721 cagccgttcg gccgcggcca gcgcgtcggc ctcggcggcg aaggccgcgc cccgtaccgg
    24781 cgagcgttca ccggcgttga ccagtcggcc gtaggtgtgc tggtcgaaca gctcggtgtt
    24841 ctgccacaac cggtcctgca acgggaccac cgcaccgttc aggtgcagcc gggccgaggc
    24901 caggttggcg ctgaccatgg gcagggcgat ggggccgccg aagatcagcg ggttgccgaa
    24961 cttgcgcagc accttggtgt ccgcgcggtc gcgcagcacg ccgaatccgc cggcgccgcc
    25021 gaacgccttg gacagcgagc cgaccaggat caccgagtcg ggcaggtccg tgccgaacgc
    25081 ctcgtgcgcg tagccgccgc cctgggggcc ggcgatcgag atcccgtgcg cgtcgtcgac
    25141 gtagaggtag ccgcccgcgg ccgcggtcag ggcgttgagt tcgacgacgt cgatcagccc
    25201 gcccatcgag ccgatgccgt cgaccagcac gatcggggtc cgtcccgcgt ccaccgcctc
    25261 gtcgagcagg gcgccgagcc cggcggtgtc gtgcgcgtcg aaccggctga ccgggccgat
    25321 ctgttcgaag atgccgcgca gtacctggat cgaggcgtgc gcggtgcggt cgacgaggaa
    25381 caccggtccg gcctcggcca tcgggtagct gggcagcgcg tcggccgcca gcagcggcag
    25441 cacaccgagg tggacgttgc cgacagaggt gaaggccgtg accgatcgca gaccgtagat
    25501 gcggtccagg atcgattcca gttcctccag gtcgtccagc cgcatccggg tccgtgcgga
    25561 ggcgaagtgc acgccggcgc ggtcgatggc ctccttcgcg ctgtgcagga gctgggggtg
    25621 cacttccaac cccaggtagg agcaggagac gaactcgacg gcctcgctgc cgtcggccag
    25681 ttcgaccacc ttgccccggc ggcagtggaa gacgtgcgag gtcaggtcgc gctcggtggc
    25741 gagggcgagc gcgtcggtcg tgttctcaag gcggttggtc agccagttct tggagatctc
    25801 cagcagggcc acagacagtc ctcagatgag tgggaacgtt cgagtgccgg agtggggggg
    25861 gtggatccgg acttgggtcg gcggtcagag ctcgacgaag aacggagtct tgccgcgtgt
    25921 gttgcgcacg aagtccgctg tgggaacgtg ccgcagggtg aagccccgga agcccggcat
    25981 ggcaaagacc cggccgaggt ggtaaccctc gcgcagccgc cggagcacct cgtcgccggt
    26041 ggggcggacg gcgagccggt cggcgagcag gaggacgacg tcgaatccgc ggtcgggggc
    26101 gcgccgtacc tggaactggc agtcggccgg gtcggccact ccgaggccgc gcagctgagc
    26161 catgaccagg tcctgggaga tcgtcgcgcc gtcgacgttg agcgagcggg gcacgcgtcc
    26221 ggtcagcgtg atccgcgagg tggggctgcc gcaggcgcag ccgccggtgg tgtgccgtat
    26281 cgcacggtcg cccatccgaa agcgcaccag gggcatcccg gtgtcggtca gcgtggtggt
    26341 gatgacctcg ccttcctcgc cgtcggccac ctcggcgccg gtctccgggt cgaccacctc
    26401 gacgaacatc gcgtcgtcgt gcacatggtg ggtgccgtcg ccctgaaagg ggcactggta
    26461 gccgatgggg cccgtctcgc tggtcgagta ggacagcgac ctcacccgca atccggggat
    26521 cgcctcggtc atgaccgccg cgcgggccgc tccgaggttc tcgccgatgt acaggtaggt
    26581 acgcagcgac gccagcgacg ccaggttcgc cgggtcggac agcaggtcgg cgcccatcgc
    26641 gggcgagccg atcagcgtgt cgattcggtg ttcgcggatg acctccagca gttcctccgt
    26701 gcgcatcgag gtccccaggg gatacgtctg cgcgccgagg cgccgggtga ggtcctgggc
    26761 gaaggagaac gccccgttca gttcaccggg gtagaggcag ttgcccaccc ggctcggggc
    26821 cgtcgtcagc gcggcgcgta cgccccgtgc gccgaggtgg gtgacccgga cgtcgaactc
    26881 ccaggagtgg tagaggactt tgcgctttcc cgaggtgccg ctggagcgca gcaccattcc
    26941 gctgtcggcg ctgtcgagca ccagatcggt caccgcgggc gggcacaagt cctcaagcgt
    27001 gtcgggcgac atgaggggta gttcggacag gtcgtccgcg gtacggacgc cctcgatacc
    27061 aggccatcgg gctgccgcgg cgggacgttt cacgatggcg tccaccgtcg ccaacaggtt
    27121 gtcgctacgc aggcgcgcga gttcgtctgc tccgagagcc tccaggtcgt ccgctagttg
    27181 aacacgcgaa ttgcttgatc ttaaagggcg aacagagatc gacacttccg cttcccccgt
    27241 cgttcttcac cgggcatccg cctgcgcccg tcggcgctta cgctacgcgg agcccgagcg
    27301 gcccgggcta gcgaaattga gccaactccc gacatgatct tcgacaaaac catcgcatgc
    27361 ggaatcggat gctccacccg gcatgatcac gctattcagc aaccggcaca caaggctgca
    27421 gcccccacgt tgacgtgcac tccaaccact tccacacaca agcgatttgc ccctggaaca
    27481 cattccctga acaacgatca cacttaagca actccagccg catttcttga tcacgacctc
    27541 tccgacacgt cgccgccgcg gcgacatttc cccagcggcg gcatttcccc gtatcccata
    27601 cggtcttcca catacccctg gtaaaccgga gtggcatgct ccatgaccct tcattccctt
    27661 cattcccttc actccccgcc cggctccatc accggtccac gacgcacact cgacgcgcag
    27721 acgcacagcg tgggcagctg ccacagcgcg ggtcggctgt agaccggttg cgggccggtc
    27781 gcgaaccggc acgacgaacg atcggactga tgccggccgg acacgacgac cgggagcgta
    27841 tccgcgccac acgcgaagca cggcgcccca gacgaagccg gcaacagcgc gctcacgaac
    27901 cttcgatgac gcgccggctg tccggtatcc gcccctcggc gtccgcgagg gctgaacggc
    27961 cgccgcaccg agaaaatcgc gcacgccccg gcccgacgcg gacagtcgtg ggcgagccgc
    28021 tacgggcacg gccggcgggg cccacgcgtc agacatccat cgcacagcgc ccgccgatgc
    28081 cgcacggctc caaggtcgcc cccactcaca aagagggccc acccgccgaa gccagtgact
    28141 ccggcggtcg gaagctcaac tcccttgcac cgtaagggcc cgccaaaggc aggacgttcc
    28201 gctccctctc cggatccgcc actcacgtcg tcggcggcaa gcgcgctgcg gtgtgccgtc
    28261 gcaccgcatt agccgtccgt tagcagaacg ccaacccggt cttcgaagct gattttcgtc
    28321 cggagtgaga gacaagagaa cacagcaacg ggagacctga tgaacaccgc caccacccgc
    28381 ttccgcggcc gtgccggccg ccgcctcgcc gccaccgtcg tcgccaccgc ggcgctgggg
    28441 ctgggtgcca ccgcctgcgg gcagggctcc gggacaacgg gcgccgccgg cccctcggcc
    28501 tcggcccagc ccacgagcgg ctctccctcc gacaagtcca actcgcaggg ccacaacggc
    28561 ggcaagtcca ccgcggcgcc gtccgccgcc cggggctcgg gcaccggcgg cagcaccggc
    28621 ggcaagcccg cctccaccgg gggcggcgtc gcccacgccg gtaaccaccg cacgatcgtc
    28681 ggcacgctga actacctcgc gcccggtaaa ctgatcgtca agccccaggg aggcggcacc
    28741 gaccaggcat tcctgatctc caacgccacg cggatcctcg gcgcggccgc gatctgctcc
    28801 gactccgacg gcagcgtgac catcggcagg gacggctacg gcacctcgaa gtgcaccgtg
    28861 aaccaactgg agacggctgc gaagaccaac agcgtcaccg tccgcgtcac catgaacccc
    28921 aagtccggcg gtgccgagac ggtcgaggag aagtaccacc cgtaagcccc ggcacccctt
    28981 cgccgcggcc accacccgtt cgaccaacgt ctacgccaac gtgctgtgcc cggaccccag
    29041 cgccctgttc acctacctca ccaccagggt cgcggcgctg ccctcgatcc agcacatgga
    29101 gaccgcagcg gtcacccaga ccatcaagac cctctgacgc acggatcgga accgcccgcg
    29161 gacgtgaccg tacgcctcgc gcttccgcct ggcccggcgt ccaggaagtg atcacatgag
    29221 cagcaagcgc ctccgaccgg caacaccatt gacatggcgg acagttcgat cgcctgacct
    29281 gtgcaatggc cgccctgcgg tgacccgaca gccgccgact gtcggacagg gcaacgcggt
    29341 tgtccgccgg gaacctgccg gggaagcggt gccgcggcgg ccggatgggg agcagcaggg
    29401 cagccagcgt ggcgtgagca tggctcgatg gctccgcacc atgcgtacat gccgccagcg
    29461 cgacagcagg gctcgtcgta gcaccgagac agcggacttc ccgaggggag tccggccggg
    29521 gccgaactcc ggccgccggc cgggcttccc cgagaagccc ggccggcggc cttttcttcc
    29581 gactgcgggt cgagcagtgc cccgcggtct ggcccttcag aggccgaaag ggtccgggac
    29641 cggcctgtgg cgcggacgcc gggcccggtg ttattccccg gcgcccccac ccaccgcacg
    29701 taccgggcct tccccgcctt ccttggcttc cccggcttcc ttgcctccct tgccttccct
    29761 gccctccgag cccccgctct taccttcatc gccccccttg tctcccctgt ctcccttgtc
    29821 gccctcgtcc cccttgcctt cccggccctc cgagcctccg gccttgcctt cgtcgcccct
    29881 cttgtctccc ctgccttccc tgccctccga acctccgctc ctgccttcgc cgcccccctt
    29941 gtcacccatg aagtcgacgc tgttgtcgca gcccatggac gagcccatcc tggtgctctg
    30001 cgcaccgggg gagccctcgc cgccgagcgc gttacccagc acgccgttga ggatcccgac
    30061 ctcgccgagg acgtcgacgt tcgtgtcgtg cgaccggcac tggctgccct gcctgacctc
    30121 gaagtcggtg ccgcccctcc cgccttcctt ctcgccatgg gcgtacgcgg tgccggcgcc
    30181 cacgaagccg aagctgccga ggacggcggc cacgactgcg gccttctgaa gcttgcgcat
    30241 tttttctccg gtggtcgaac ggatgcaatc cgtgatatag cgacttcgta cagtcatagg
    30301 aggctaatac gaaatattcc ggaggtaatc gatgacgcgc cggattcacg gccgttgcga
    30361 acgagcagct gtcgggagcc gccctgcgcc ctgggcagga cgggcatcga ctggccgcga
    30421 caggtgcaga cactccgctc caacagccct gaccccaggg gccggcgtgc gcgccacaca
    30481 tggcgtcgct cctgcgcccg ccatcacagc cggcggagcc cacgaacaca ggacctcaca
    30541 ctcgtgcttg cccaggtgag ccagctccgg acggcgcagc tcgtgatccg gggggaatgc
    30601 gttgagccag cgcctgatcg ccactgtgcc gcgccgcgct ccgccatctc gcgtacccgc
    30661 atccatccgc ttcgctgctg agggacgggg gcgccgtacg gcttggtgct cgccgcgacg
    30721 atccgtaggc cgtccttccc agcggaggcg tggcctttcc cggctgctcg ctccgtagcc
    30781 agggggccgg accccgcccg ctccgcggag aggtggagca cggtcgggga gctgtccacg
    30841 gtgatggcgc tcggcgtctt ccctggtgca gtccgggcca ccgtggcctc ttcgtccgtc
    30901 ttggcgcctg ccccatcagg ggtgggaggc agagcgggcc gtgcctggac cagaatcact
    30961 acgcggtgcg tggtctccgt tccggtgccc tgccgtgcgc tcatcgttcc gccctccctc
    31021 actcgctgct gacgaccacc ggatggaagc tgaccgcccg tccgtgacat gaggtcgatg
    31081 tgatgcacaa cacagggcgg ggtggggacc gttgaggtgg tgtcgcatga cgtcccccgg
    31141 gctgctgcag acggtcaaca gtcctgtcgc ttatgcaggt tgacgccggg atcggcggcg
    31201 tccactggat gccgtgggct tccacatgac tggggcacgg cggccgaggg gcacgcggtg
    31261 gtcggccgga ccggtcggga cggcacaccg atccgaccgc gcggcaccgt cgcgccaggg
    31321 catccccgtt ccttcacttg gtggaacggg aacctcgcac ggagtgcgcc ggaccggcag
    31381 gccggatgct gtgccggcgt gccaggctga gggctgccgg tcgtcgtgca tcaccgggtg
    31441 cggcgccgcg cgcgtgaatc gccgggtgcg gcgcgttgcg cctcgtgaag ggcttgtctg
    31501 tccagagcgg acgatcacgg cagagggcag tacccactac tccttgccac tctcaacata
    31561 tagcggactg ggggccttgc ggcaaggccc cggtcatacc gcacaatcgc tgacctcagc
    31621 cagaaccttc ggtaatgggg gcttttccaa gtgcatgtgt tgttctcggc ctgtgggtcg
    31681 tgtggcggtg gcgagccggc gttgggactc catccgcgat cgcgggcgct cggcgccgag
    31741 gtgcgcgcag atgcgccgtt ggacctcgcg ggcgcgacct cggatcggag ctggtgacgt
    31801 gaatcccctg agcaccagcg tgttcgacct tcccgaccgc ctctccccca aggccgaccc
    31861 gacactgata gccggcgacg agctgcactt cgcggccatc gcggagagcc ttgagcagtc
    31921 gatcgccgaa ctgtccgacc gcctcgacgc cgagctgagg gcgcccggcg gcatcggccg
    31981 ccaggcgatg gaccgggacg cggaggtcca gcgactgacc gggcgcctgc gcgccctgcg
    32041 tcgcttcgga tgggatctgt gcctcgggcg cgtcgtcggc gcggacgacc ccgagcccgt
    32101 gtacatcgga cggctcggcc tcaccgacag cacgggacgt cggctgctgg tcgactggcg
    32161 ctcccccgcg gccgcatcgt tcttcgcggc gacccacgcc aacccgatgg gtctggcgag
    32221 ccgccgcagg taccgctgga cgagcggccg gatcagcgac tactgggacg aggtgttcac
    32281 cgccgacgga ctggacgggc attccgcact ggatgaccag tccgcgttca tcgccagtct
    32341 gggcagcacc cggtcgtccc ggatgcgcga cgtgctggcc accatccagg ccgaccagga
    32401 cgccatcatc cgggcgggat cccggggcgc tctcgtcgtc gacggcggtc cgggtacggg
    32461 caagaccgtg gtcgctctgc atcggaccgc ccacctcctc tactccgacc ctcgcctcgg
    32521 ccaccgtcac ggcggcgtgc tgttcgtcgg tccgcaccag ccctacctgg cctatgtcga
    32581 ggacgtcctg cccagtctcg gggaggaggg cgtgcagacc tgcaccgtac gggacctcgt
    32641 cgccgaaggg gccggagcgg cggtcgaggc cgacccggac gtcgccctgc tgaagtcgtc
    32701 cgcggacatg gtcaaggcaa tcgaggcggc cgtcaggttc tacgaggagc cgccggccga
    32761 ggggatgacg gtcacgaccg actgggccga catctggctg agcgcggacg actgggccga
    32821 ggcgttcgac gcgccggatc ccagcactga gcacaacgag gcgcgcgagc agatctggga
    32881 ggaactggtc acgatcctgc tggacaagct cgacggcgat gtctcgcccg acgtgttcca
    32941 cagctcgctg cggcacgacg aggagctggt caccgccctc aaccgcgcat ggcccctgct
    33001 cgaagcgacc gacctcgtcg gagacctgtg gtcggtcccc gcgtatctgc ggctgtgcgc
    33061 tccctggctc agccgcgatg aggtgcgcag gctgcagcgc aaggaggcgc cccaggcatg
    33121 gacggtgtcc gacctgccgc tcctggacgc ggcgcggcag cggctcggcg acccggaggc
    33181 ggcacgtcgc aagcgccggc aggaggccgc cgtcgccgcc gaacgcgccc gcatggccga
    33241 cgtcatcgac aacgtgctgg cggccgatga cgacggtgaa ggcgcagtga cgatgctgcg
    33301 cggacaggat ctgcgggaca ggctgatcga ccggaccgcc gtgcccggcg ccgacccgga
    33361 ccggctcgcc ggcccgttcg cgcacatcgt cgtggacgag gcgcaggaac tgaccgacgc
    33421 ggagtggcag atgctgctgc tgcgctgtcc gtcccgaagc ttcaccatcg tcggggaccg
    33481 cgcccaggcc aggcgcgggt tcacggagtc gtggcaggaa cggctgaagc ggatcgggct
    33541 cgaccggatc gaggtggcct ccctgagcgt caactaccgt acgccggaag aggtcatggc
    33601 ggaggccgag ccgttcatcc gggccgagct ccccgacgcc aacgtgccga cgtccatccg
    33661 cagcggcggt gtacccgtca cctacggatc cgttgcggat cgggagtcga tcctcggcgc
    33721 ctggctcgcc gcgcatgccg atgggatcgc ctgcgtcatc ggcgatccca cgttccaggc
    33781 gacgtcccgt gtgcggtcgc tgaccccgga actttcgaag gggctggagt tcgacctggt
    33841 cgttgtcgtc gacccggagg agttcggcaa gggcatcgaa ggagcggtcg atcgctatgt
    33901 cgcgatgacc cgggcgaccc ggcaactcgt catcctgacg agctcctgac gggctcctga
    33961 cgtcgacccg ttgtgggcca cgtccccgat ccgccaccgg gccgccgctc ctcgtggcgc
    34021 cccggcttga ccggttcctc gtagcgctcc cgggtcccac ggccgatcat ctcggacatc
    34081 acccccgcgg acccgggtgc gacacccctc tgtgccgcca actcgcccag aacacccgcc
    34141 cattgacacc atgcggcggc ctacccgggc cgggcagggt gcctgggaac ggcgcgtgaa
    34201 gccgtcctgc ccctgccgcc agtgcgtgga acggcaaacc acccaacaga acaccggcgg
    34261 catcagcgga ccacgcaccc acggacaacc ccggtcccgc gtcatcaccg gcgacgacgc
    34321 atcggcgcgc atcgcgcgcg cgggagcgtg tgtcgagcgg gccggccatg gggaacatgc
    34381 ggccacgggc cgggcggcac cggcctgccc aagaccaccg tccaccgcct gccggcgtcg
    34441 atgtgcgacg ccgggcgaca ccaattgccg gaggctctta caagcgctga cccggtgagc
    34501 cgagttcggc ctgccgaaga ctgcggaaca ccgcgggggt cgcccagccg cgcagcatgg
    34561 cgtgaatcgt cgatcggaat gccgcctcgg ccgtgtgggc gtcgaagccc ccagccagtt
    34621 cgagcgtcac gagcccgtgc agggtcaccc agagcgagag ggcgatcgac gtcacttcgc
    34681 cggcgaggac ggacccttcc acaccccggt cgatcgccgc gatgagcggc cggatggggt
    34741 cacgggcgcc gaccgccccc gacggctcga aggactgcac ccctccgaac agcaccatgt
    34801 acaggtgcct gtgtccgcat ccccatcgcc ggtacgcgac ggccagtgcg tacatgtcgg
    34861 cgagggggtc ctgagaagtc ggcaccgccg acaggtcctg gaacaggctg gcgacggctc
    34921 ggtcgcgcac cgccccgatc aacccgtcct taccgccgaa cagggagtac accgccgtcg
    34981 tcgacgcgcc ggcggcagcc gccacggcgc ggactgtgac cgactcccgc ggacccgtgg
    35041 cgagcagctc ggtcgcgcac tccacaagcc gctctttgac cgtctcgtcg ttcgtcctgg
    35101 gcctacccac gacgagaagc ctacctcctc tgataacgtc gttttgaaac ggcgttccga
    35161 aactccgggg gtccatcttg cccacattcg ccctgcgcct tgtccgcttc gccggacgct
    35221 tactactggc gctgactgcc gtcacaacgc tggttgttgt ctttctcgta ctgatcgtcc
    35281 tcacggacgg ggccggctcg ggactcgccg catggctcac gacccttgga ctcgcttctg
    35341 ccgccgcact gtggcggggc cgcggccgta cccgggcggc gcgactcgtg ccgttcctac
    35401 cggtggttgt cgcggcggca ctgacggcgt cggtctgcat ccctaccgtg cccacgaccc
    35461 ggcggtaccc gcccgccctg ccgttcgtgg ccacacagca ctggaaactg gccacaggca
    35521 gccaggtcgc ggtgtaccac tacccgcccg cagcacccag aactcgacac cccatcccgc
    35581 tcgtgtacct caacggtgga ccagtccgcg gcatatcggt actcgaccac cggttcctgc
    35641 aactcctggc gcgccagggc tacgacgtct acgcctacga acaggccggc ggcggccgca
    35701 gcgacctgct ctccatggac cagtacacga tctccagatc agtccgtgac ctcgacgcct
    35761 tcacccgccg tctggacagg ggcaaggtcg acgtcctcgg cttctcgtca ggcgcggtcg
    35821 tggtcacacg tgccctggcc gccccctccg tcgccgcaca tctgcaccgg gcgatcatcg
    35881 ctgagcccgg cccgatggac ggctccacgt cgaggatcac cgggcaccag ggacgcccat
    35941 ccgcacgcgg tctcgcgccg ggcatgaccg gaccacgatc aacgcaactc ccccggtacg
    36001 ccgtggcatt cggactcatg cgactcgggc tcctcacccc tgacaccgga ctgatcggac
    36061 aggctgaagg cgacaacgca ttcaccgccg cagacctcgg cagcgacacc gcgtccgcct
    36121 actgcgcgcg cgacgcgcac cgcatcccga ccgaagacac ggcacagaac ttctccttca
    36181 gctccgctcc cagcctccac atccagcaga cggtgaagga ctcaccctcc agcgccccgc
    36241 aactgaggcg ctccaagacg cccgccatgc tgatgatcgc cgagtgctct tcccaggttc
    36301 gccaatggga gaccaccatc cttgccaacg accccgctgt ccaacgcacg cagtacatgc
    36361 cggaagtcgg gcatcacatg tggaacggtc tggatgacaa caacgaccga gccgccgccg
    36421 tcatcacctc gttccttcaa ggcaagccgg cccccctgcc gaactacccc acccgcgacg
    36481 agatccccgc cttcctacgc gaccacaagt gacgccccca gcccgtcccc ggcagctgcg
    36541 cgtcaacgat ggaagctgca tgggtcccac ctccagtaca gccaccgagt gctccccaga
    36601 agagacgccc cttgttcggg ccggccttcg gcccgatgat gcaggcacgg cggttcggca
    36661 gtgccctggg cgttcctctg cctcgacggc ccggccatca ccgccggcgc cgtgctcgcc
    36721 accagggacg gcacggcgac agcgaagcaa tggcatagct gcacagttca gtgaattcgg
    36781 cccgaccgag gccgcgacca tctgctcgcg gcaggacctc ggcgccagtc cggcatccac
    36841 cggcattccg gcatccgccg gaacgcatct cacgccatcc gaaggggaac ggccaggaac
    36901 cggaccgtag gtcagcgcgt cacagtggcg tgcggtggtg gaagggagga gcagtggcgg
    36961 cggaatacgg gagacgcagt gcgtcgcatg ggatggcctg gccttggttc ggggctgcgc
    37021 tggttgccgt ttcctgcgtc ctgaccgcct gcggaggcgg cggcagcggc tcggggacgc
    37081 gctccgcacc gtcgcgccgt tccgtcgatc cgctcaccgc gacgccggcg ccgtctcccc
    37141 cggcgggaac ctcggcgtcc cccgggacgg cctccgcgtc accggactgt gtcgccggcg
    37201 gctccgccac cgtcacccac ggccctgggg acgcctccgt ccgggacctc tgtgtgcgcg
    37261 ccggcgcgac ggtcaccgtg gttctggggc ctcgctcggg gagcgcctgg ccgcggccgc
    37321 acagcagcaa tcccatgctg gccgtggtga cttcgaccgc caccggccgg aacggcgcca
    37381 cccaggtcac cgtgcgggcc gcgcgcaccg gcctggtgac ggtgacctgg ggtccggacg
    37441 acactcctgt cttcgccctc cggctgaacg tggcggggta tccggtgcag tgatcgggac
    37501 gcgcacggcc ggtgcgcgtc ccgcaggtgg ggtgcgcacc ggccgccggg tgacggtgat
    37561 ccgtcgtggt cagtcgttac gggtggccac gaggcgccgt acgtcgaggg accatatgcc
    37621 gcgaccgtgg gtggcggcgt acagcttgcc gtccgggccg agtcgcagtt gcatcacggc
    37681 cgcggtgggg aggtcgtgcc ctgccacctg ccaccgggtg gcaccggcgg gccggtagaa
    37741 ggtggccagg tcggtgccga gggcgaggcc gccgttcggg agcagcttca ccgtgttggc
    37801 gggtacgtcg ggcaggttcg ccgagatgtc cgtccagtcg gtgccgccgt tcttcgactc
    37861 gaagacgtgg ccgacgcctg cgccgggtcc ttcggtccac ttgcgggaga agccgttgac
    37921 ggccacatac acatgccggg cgttggccgg gtcgacctcg aagccggaga ggtagcggtt
    37981 ggggagggtg ccgtcgaccg ggagggtgag ctggtgccag ccggtgccgt cggcgttgcc
    38041 gaccgcgatg ccccggctga agcccttgct gtcgcagggg ccgcaccagc cggcgtacac
    38101 ggtgccgccc gaggacgtca cggcggtggc cacgtggccg tcgccgaggt cgtaggcgtt
    38161 cttccactcc gtccgggacc ggatcgcgaa gcccttgttc tgcacccata catgccggcc
    38221 accggccacc caggtgttgc cgtccttggt gtcggcggtg atcggggcga tgaagcgggc
    38281 gccggcaccg cccaggtcct tgtccggcgg ggcgacctcg tactcggtgg ccttggtcgg
    38341 gtccgtgttc cacgagccgt cgttgacacc gcagttctgg gtgacccaca tgtcgaggta
    38401 gacgtactcc gccgcgatgt tgcagccgtt ggcggggtcg gcgatggtgt cggcgccgtc
    38461 gccgccgaag ttggaaccca tgaccttgtc ccggccgcgc aggatcgact ggccgttgtc
    38521 ctggaggccg ccggtcacgg agacgccgcc gtgggcgagg tccttgccga cgcccaccga
    38581 gtagtactgg agggtgtcga gggtgccgtc gttgagggac tgccagtcct tcgcgtggcc
    38641 gcccgagtcg accgcaccgt tgagcggacg gcggtagatg ccgccgtcgt tgccgacgta
    38701 cgcccaggtc ttgccgtggt agctgccgat cgcgaccgcg tgctgatcgg agtgggtggt
    38761 ctgcgagcag tcgccggtct gcttggccgg gtcgatgctc cagcagggga aggggaagtt
    38821 ccagtacggg ccgggtgtgg tccagctcgt accgccgttc ttggtctcga agacctcttc
    38881 caggcccagg tacacgtggt cggcattggc ggggtcgacc tggaggaact ggttgtacca
    38941 ggactggatg ccgggctggt agcccgcgct ctggagcgcg gacccggatg ccttgagctt
    39001 ggtgtagtcg gcgacctgcg tccacggccc gaacggcgag ccgttcttcg acacgtacac
    39061 gcccttgagg ccgctgtccg ggttggcggt ggtctgcgcc ggcgactggt cgatggcgta
    39121 cagccgcgag ccgtcggcag cggcggcgaa cgtcatgttg ccgacgtcgg cactgccggt
    39181 cggcaggtcg ccgagcccgc tgaccggctt ccagccgccg tcctgcttgg cgtacagccc
    39241 gttgtaggtg tctccgccgc gccagccgac ggcgagcagg accttggacg ggtccttcgg
    39301 gtcgacggcg atgtcattgg cgatgttctt gtacggggcg ctcgggtcgg acgccttcga
    39361 accgtccggc agatagtccg ggttgggggc gaactccagc ttccacggac cggacagggt
    39421 ggtggtcgag tgcgaccaca cgccgcggct ggtcgccgcc cagaccgtgc cgcccacgaa
    39481 ccgcaacgcg tggatgacgg tgctctccag ctcggcgccg cccacccggt tgccgggccg
    39541 gaactgcccg tgccgcggat cgcccagaac gtagacgccg gtacctacga aggcggttgc
    39601 ccccgtgttc gactcgccgg tggcgtacca gaggcgcttc ttgccgtcca gggccagggt
    39661 ccccgtggac agcgagggga gtttgtcggc gatcggctcc cagcgtccgc cgccggtctt
    39721 cgaccggaag acgccgccgt tggcgccgcc cgcatacaca tacccctggt cgtcggctgc
    39781 gatcccggtg atccgaccgg tcaccttccc gaagccgccg ctggagttgg agttcacgtc
    39841 gcggtagcgg gggtcgtcgg cgttgtacgc cttcttggtg acgtgatccc agtcgcctgg
    39901 cgtgtggcgc atcgactgga gctgctgcca agcggctccg taggcacccg gcgcgaccac
    39961 accgggggcc gtgcgtgcct cggtgaactg ggcagtggct tcggcggagt tctccgcctc
    40021 gtcggagtcg ccctccgagc cgcccggggt ggcggcagcg gactttcccc gaccggcgtg
    40081 cgccgccttg atgtgctgcc gaccgatgtc ggcctggtgg cgcgcgttcc agggccgggg
    40141 tctggactca cctgacgccg cgaacgactg ggtggtcgcc agtccgaacg cggcggctac
    40201 ggcggcgcag gtgatgaacc gccgacgatg ccgttggggc accatgccct ctcctccctg
    40261 cgccgagtat ggggggctcg acgcggagga gatcttggcg tgcccgcgac agcgctgcga
    40321 agggggccgc aggaaaaatg gtgcggagtt tacgtttgcg gcccgctcgg ctcgaaactc
    40381 ccctaacttc ccgttgacaa ctgctagttg atgttgccca cggtgcccgc ggagtcggcg
    40441 ggaccggccg ccggcaaccc gagcgagtcc ggcacagcgg ctggcgagcg gacggcggcg
    40501 ccggtagggc tgcggtgccg gtggggcgcc ggtgccgctt gcggctcctt atcttccccc
    40561 cgtcccctca cgcatcactc acgcacgtgc cggaaagccc gcggccgtca ggtcccgcca
    40621 cccaccggcg ctcaaccggc gagtcccccg agcagtgccc aagtacggcg ccggtcggcg
    40681 tctccggcga tctccgtccc ggagaacacc acctccgtcg ccccggcgtc ccgatagcgc
    40741 cgcacctcgg cggcgaccgt cttctcgtcg ccgatcaccg ccacatcggc cgcccgtcgg
    40801 ccgccggaga gttcgatgac ccgcgcatag gacgggatcc gctcgtagaa cgcgagctgc
    40861 tcgacggcct tctcccgcac agagtccaca tcgtcggtca ccacgccctg caccagcgcg
    40921 acgatccggg gcgcgggccg gccggctgcc gatgcggccg ccgtgacggc cggaacgatg
    40981 tgctcgctca gggcgcgcgg cccggccaga tagggcagga tcccatccgc cagctcaccg
    41041 ctgacgcgta gcgcctgggg ccccatcgcg gcgacgagca acggcacgcc cgcctcggcg
    41101 cccggcaccc gggcggggat cg
//
