LOCUS       NZ_CP047146            22742 bp    DNA     linear   CON 30-JAN-2024
DEFINITION  Streptomyces sp. GS7 chromosome, complete genome.
ACCESSION   NZ_CP047146
VERSION     NZ_CP047146.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. GS7
  ORGANISM  Streptomyces sp. GS7
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9067183)
  AUTHORS   Li,J., Ni,J. and Li,Y.
  TITLE     Multiple polyene macrolides produced by antifungal Streptomyces from
            gut of Macrotermes barneyi facilitates the termite-fungus mutualism
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9067183)
  AUTHORS   Li,J., Ni,J. and Li,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-DEC-2019) State Key Laboratory of Microbial
            Technology, Shandong Unversity, 72 Binhai Road, Qingdao, Shandong
            266237, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 20-NOV-2019
            Assembly Method                   :: SPAdes v. Nov-2019
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/30/2024 05:53:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,019
            CDSs (total)                      :: 7,925
            Genes (coding)                    :: 7,616
            CDSs (with protein)               :: 7,616
            Genes (RNA)                       :: 94
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 309
            CDSs (without protein)            :: 309
            Pseudo Genes (ambiguous residues) :: 0 of 309
            Pseudo Genes (frameshifted)       :: 107 of 309
            Pseudo Genes (incomplete)         :: 258 of 309
            Pseudo Genes (internal stop)      :: 29 of 309
            Pseudo Genes (multiple problems)  :: 79 of 309
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:40:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3657061
            Orig. end                         :: 3679803
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP047146.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Jinfeng Ni.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22742
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="10"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22742
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22742
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12742](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12742)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    complement(1323..1338)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.41"
                     /tool="antismash"
     CDS             complement(1411..1623)
                     /gene="allorf_3658472_3658684"
                     /locus_tag="allorf_3658472_3658684"
                     /protein_id="allorf_3658472_3658684"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGLPDDLPVGVDHLGRHSARPGGARAARPEPRPPARPGRRPRAAR
                     PRPRHEPPRRWSADVQGRNSPSRCR"
     CDS_motif       complement(1555..1623)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MGLPDDLPVGVDHLGRHSARPGG"
                     /locus_tag="allorf_3658472_3658684_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(1411..1554)
                     /prepeptide="core"
                     /locus_tag="allorf_3658472_3658684_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.40"
                     /molecular_weight="5389.1"
                     /monoisotopic_mass="5385.9"
                     /core_sequence="ARAARPEPRPPARPGRRPRAARPRPRHEPPRRWSADVQGRNSP
                     SRCR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGLPDDLPVGVDHLGRHSARPGG"
                     /leader_location="[1554:1623](-)"
                     /alternative_weights="5407.1"
                     /alternative_weights="5425.1"
     gene            complement(1861..3546)
                     /locus_tag="GR130_RS16025"
                     /old_locus_tag="GR130_16025"
     CDS             complement(1861..3546)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018853325.1"
                     /locus_tag="GR130_RS16025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_16025"
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="WP_159505368.1"
                     /transl_table=11
                     /translation="MRERAHTAVPAAVAQLSVKDVTKSYDTRTVLDQVSFTVRPGEKAA
                     VIGENGSGKSTLLRLLAAAELPDVGEITVSIPGGTGHLAQTLDLAPHRTVQDTVDLALA
                     ELRAMERRLRTAEQRLGEASKDELAAYGELLIAYEERGGYEADARVEAAMHGLGLAGIT
                     RDRVLGSLSGGEQSRLALACVLAAAPELLLLDEPTNHLDDAAVRWLEEHLRAHRGTVVA
                     VTHDRGFLQRIATTILEVDREARTVRRYGDGWAGYRAAKATARRRAEQGYADWLQEMAR
                     TEELLEAAGKRLAGTGKDPRQGFGKHRRSHEAKLGGQVRAARERLAHLQRNPVAAPPQP
                     LRFTAALPAAGGEPPADRPSPSSGLRSGHGCPLAELDGVAVGERLRLDGLLAIAPGQRL
                     LVTGGNGAGKTTLLRLLAGELEPDAGAVRRPARIGYLAQELPARSTRLPLLAAFAARRP
                     GLPEEHAEQLLALGLFRQEDLHIPVADLSAGQQRRLQIARLVTRPADLLVLDEPTNHLA
                     LDLVEDLEAALAAYPGAVVAVSHDRGFRERFPGQRLELHRGRRC"
     gene            complement(4075..5769)
                     /locus_tag="GR130_RS16030"
                     /old_locus_tag="GR130_16030"
     CDS             complement(4075..5769)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986396.1"
                     /locus_tag="GR130_RS16030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_16030"
                     /product="mycolysin"
                     /protein_id="WP_236573050.1"
                     /transl_table=11
                     /translation="MAGAGVCLAAAVVPSAFAGNSPQAHAPTPAGTCTIRPAEKNSEAP
                     LSCLGVTASLDHLPAVGEQATLTVNVKAQTDVKRAGLSLQLPPALRISDGEGSGLTAPA
                     TDTFGQRTSRILALTPGTRTVSLKVKAVAAGPAQIQADISDVDHPDPRRAGHDSVELTV
                     SKTNGSSDKGISVTKAHPAPVHHPTPGARKERPVTPEAPAPDRASAASAPAAPRTGGRA
                     GDSSQVCISGTFRNRFQSAEGGSWNSKANRDEPVHNANVTLWGQPTANSGTQKLATGMT
                     GNKDGSFNLCYTPTTSVTSKVWVEFRTQAGQSWSVVDGNGRLYTTATYSQDNVSGSTRL
                     GNVYANEGQSRAWHALDTLNKLWWNRGSTTNCWASSQQDGHCTPITVQWYPGSTDGTYW
                     STNEDKIHLADNDPDSEHTVVHESGHALMGKLYKGWWPNVTNCSPHYVSRTSSTSCGWT
                     EGFANAVAFHTFNDTTYYWGNGSSQNLANDRSTTGIDPGDACEARVATALVDLWSQVDG
                     GWSKSNTMMTKTQQSSFREYFVTDRPDYGLDTGAKARNILYNHTIQY"
     misc_feature    complement(5817..5827)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     CDS             complement(5970..6134)
                     /gene="allorf_3663031_3663195"
                     /locus_tag="allorf_3663031_3663195"
                     /protein_id="allorf_3663031_3663195"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MLQRQIASARRHRRAVVLCTSRRRQMSPVTTEHPPTPLFLCLVLF
                     SHGSDMCKR"
     CDS_motif       complement(6108..6134)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MLQRQIASA"
                     /locus_tag="allorf_3663031_3663195_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(5970..6107)
                     /prepeptide="core"
                     /locus_tag="allorf_3663031_3663195_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.30"
                     /molecular_weight="5133.1"
                     /monoisotopic_mass="5129.7"
                     /core_sequence="RRHRRAVVLCTSRRRQMSPVTTEHPPTPLFLCLVLFSHGSDMC
                     KR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MLQRQIASA"
                     /leader_location="[6107:6134](-)"
                     /alternative_weights="5151.1"
                     /alternative_weights="5169.1"
                     /alternative_weights="5187.1"
                     /alternative_weights="5205.1"
                     /alternative_weights="5223.2"
     gene            6334..6660
                     /locus_tag="GR130_RS16035"
                     /old_locus_tag="GR130_16035"
     CDS             6334..6660
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603908.1"
                     /locus_tag="GR130_RS16035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_16035"
                     /product="Lsr2 family protein"
                     /protein_id="WP_159505370.1"
                     /transl_table=11
                     /translation="MARKVVTLYTDDRTGEATSKVTTHTFSLNGVQYQIDVAPDGYDLL
                     LEAMAPFTKAGRKTGRTRESLKATAAGPDDGAAIRAWSKGAGYEVSNHGRVPAEAREAY
                     DKTH"
     gene            complement(6758..7867)
                     /locus_tag="GR130_RS16040"
                     /old_locus_tag="GR130_16040"
     CDS             complement(6758..7867)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="GR130_RS16040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_16040"
                     /product="MFS transporter"
                     /protein_id="WP_159505371.1"
                     /transl_table=11
                     /translation="MYAGAALGPLGGGVVAPMLPQIADSLNASTSATTLTVTAYFVPFA
                     LVQLVSGTVGERWGRRRTVLLAYLVYLIASLLGAIAPNIALLLVVRAVMGTANAFVSPL
                     LLSGLADMVPAHRLSRSVGLLASCQAAGQSLSPLLGGVAAAANWRWAFVGVAAAAGLLA
                     LAPPPGGARPGAQAPRLRPLVNARMGLLSVAAFVSYFGAAGLPFMVSLHAEEHLGIRPD
                     LTGVALLGFGLTGLLLGASWGSLGDRFGARRCGGIAAALGAVLVALTGSTHSLPALVLC
                     WTGAGIAYSMLNVCLQNLTVREVPDNRGGALSAVSAFRFGGAAMAPIALLPLYHADPPL
                     SFVIGGGSLLLASAGLATLRSPQTGNSAC"
     misc_feature    8025..8042
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.9"
                     /tool="antismash"
     gene            complement(8142..8996)
                     /locus_tag="GR130_RS16045"
                     /old_locus_tag="GR130_16045"
     CDS             complement(8142..8996)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019074575.1"
                     /locus_tag="GR130_RS16045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_16045"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_159505372.1"
                     /transl_table=11
                     /translation="MDVELRHLRAFVAVARQQSFTRAAEKLTITQPALTRTVQQLETAL
                     RVRLFNRSSRHVELTNVGNSFLAQVERVLNELDRAMNALSEQVSIRLGFSWLMPDPWAQ
                     RTISEFERTSGSTVNLMRTDDPIQALQRHVIDVALVRGGVRSSAPVKTVHLFDEPRAAV
                     ACAAKSEVSRLDEVHWGDVPRWPLVENVVSGATGHWSWAPGKGPRDVIETTNYDEWVES
                     VAANRGIGVAPTVGVRRINHPGVTFVPLVNAPPVPVELAYLPHMQELLLRRFIDVAIAA
                     VHR"
     CDS             complement(9033..9251)
                     /gene="allorf_3666094_3666312"
                     /locus_tag="allorf_3666094_3666312"
                     /protein_id="allorf_3666094_3666312"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSAAARARSPDRTWIGARLAGRRTGPPPDSPPTHTHLARNLVCCT
                     ASTGWALLRSLICPSRPHPERSQSVRT"
     CDS_motif       complement(9201..9251)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSAAARARSPDRTWIGA"
                     /locus_tag="allorf_3666094_3666312_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9033..9200)
                     /prepeptide="core"
                     /locus_tag="allorf_3666094_3666312_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.40"
                     /molecular_weight="5796.6"
                     /monoisotopic_mass="5793.1"
                     /core_sequence="RLAGRRTGPPPDSPPTHTHLARNLVCCTASTGWALLRSLICPS
                     RPHPERSQSVRT"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSAAARARSPDRTWIGA"
                     /leader_location="[9200:9251](-)"
                     /alternative_weights="5814.6"
                     /alternative_weights="5832.6"
                     /alternative_weights="5850.7"
                     /alternative_weights="5868.7"
                     /alternative_weights="5886.7"
                     /alternative_weights="5904.7"
                     /alternative_weights="5922.7"
                     /alternative_weights="5940.8"
                     /alternative_weights="5958.8"
     CDS             complement(9083..9280)
                     /gene="allorf_3666144_3666341"
                     /locus_tag="allorf_3666144_3666341"
                     /protein_id="allorf_3666144_3666341"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MPPLHRAGGACRQPPAREARTGHGSAPDSRADEPAHPQTHRRRTR
                     TSPETWCAVRHRPGGRCCVH"
     CDS_motif       complement(9206..9280)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MPPLHRAGGACRQPPAREARTGHGS"
                     /locus_tag="allorf_3666144_3666341_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9083..9205)
                     /prepeptide="core"
                     /locus_tag="allorf_3666144_3666341_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.10"
                     /molecular_weight="4480.9"
                     /monoisotopic_mass="4478.2"
                     /core_sequence="APDSRADEPAHPQTHRRRTRTSPETWCAVRHRPGGRCCVH"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPPLHRAGGACRQPPAREARTGHGS"
                     /leader_location="[9205:9280](-)"
                     /alternative_weights="4499.0"
                     /alternative_weights="4517.0"
                     /alternative_weights="4535.0"
     gene            9386..9688
                     /locus_tag="GR130_RS16050"
                     /old_locus_tag="GR130_16050"
     CDS             9386..9688
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003987675.1"
                     /locus_tag="GR130_RS16050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_16050"
                     /product="DUF1330 domain-containing protein"
                     /protein_id="WP_159505373.1"
                     /transl_table=11
                     /translation="MAKGCKGYLVGTYRSVRDPEKLAAYGELAKPALEAAGGRIMARGG
                     RVTAFESGLPERTVLVEFPSYDAAVAAYLSEDYQQAVAVLDDGADRDVRVVEGLD"
     misc_feature    9605..9607
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10001..12742)
                     /gene="lanM"
                     /locus_tag="GR130_RS16055"
                     /old_locus_tag="GR130_16055"
     CDS             complement(10001..12742)
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0018081 - peptide cross-linking via
                     lanthionine or 3-methyl-lanthionine [Evidence IEA]"
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lanM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="GR130_RS16055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_16055"
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="WP_159505374.1"
                     /sec_met_domain="DUF4135 (E-value: 7.1e-71, bitscore:
                     238.2, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 5.2e-23, bitscore:
                     80.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNPTLGVQAFLPFYQYVLPLETFTENLAPQLAATVAEEDREKVT
                     AKLWQVALHVVEDHSYRTLIERFHHFRAGRGLPLDPDSSIGIDAFRLALRHPDTCEAIL
                     DAYPVLRRRLARITENLRKAYARMLAAFRDDRAQLTDIAGIGAQETIREVSLSNSDPHN
                     GNQRVVFVTTTSGAQLVYKPRPLAGDAFAHAVFEAAEPYVQHSLSGCVPASISPGGHGW
                     QAMLAGKPMTSDAQAGRYFYRLGALICLFGALGATDLHDENLLACGEFPCVVDTETLLR
                     AHFGAAMKDTLTDTLVEQTRLSPASTLLLPVNNPHSVIDVMLAGVGVLGEQRSSLKNPT
                     VVDPESDGIRVEWRTFTHRHSDNVPSLKGEQLAIGDYFVDVMSGYRDALECVRSGAIDA
                     VLDRFADMPVRCLIRATEVYARYLDASTHPTYLRDENETRRLFGLLRRFHKTLTPEQND
                     ALAAAEHAALDAGDIPYFTTLAGDTDVCAYGGEPWPLFHRSPLATARRGLAMARERHDR
                     FHRFLIEECLGHIAPDAGGLWRHSVFGPTLVPAGPGTWGGRIAEVIGDLAVTSGNEPEH
                     GAGAGAGWIGSIGPDRHTPTINPGNHVAFHDMGGIRRAVASAGRHSTAHAAEVGLRELT
                     DTYGEQLDALPESVFSGFASQLLSMPDAIDDAWLDTLLEKIAKRGEDREGDLSNGPAGP
                     LMLLLSRMESGIPVRAASLDALARTAFDPHGPRPKGAGWEVAHGQLGVMWAKARAGRLM
                     SHGQWRREAAEWLERHLPDCRPTLAGWCNGAAGLLLAAGEIGRRTGLDDLVRAHAERLA
                     QAAVALPDDRPVDLSVCHGTAGVIQCLLAASRHLDDPTLIDLARSYQHRVLAQARQTGF
                     YVGAPGHTSLVGYMLGWAGVADSDLMLNTPELPNGAPTAFLC"
     gene            complement(12994..13122)
                     /locus_tag="GR130_RS41340"
     CDS             complement(12994..13122)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GR130_RS41340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_268254004.1"
                     /transl_table=11
                     /translation="MSDDLLGTYDETQLIEMSQEPEQESAPNASQIGCSFSFCFRD"
     CDS_motif       complement(13036..13122)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSDDLLGTYDETQLIEMSQEPEQESAPNA"
                     /locus_tag="GR130_RS41340_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(12994..13035)
                     /prepeptide="core"
                     /locus_tag="GR130_RS41340_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.40"
                     /molecular_weight="1442.6"
                     /monoisotopic_mass="1441.6"
                     /core_sequence="SQIGCSFSFCFRD"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSDDLLGTYDETQLIEMSQEPEQESAPNA"
                     /leader_location="[13035:13122](-)"
                     /alternative_weights="1460.6"
     gene            complement(13506..14471)
                     /locus_tag="GR130_RS16060"
                     /old_locus_tag="GR130_16060"
     CDS             complement(13506..14471)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014627162.1"
                     /locus_tag="GR130_RS16060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_16060"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_159505375.1"
                     /transl_table=11
                     /translation="MESDYDELDRRLVHALQIDGRAPFSTLAEVLGVSDRTVARRYARL
                     RSAGAVRVLGGVDPTALGAILWFLRVRCAPAASLPVAEALARRPDTSWVSLSSGGTEIT
                     CVVRTESEADSEALLLAKLPRTPRVEGVTAHSVLHAFYGGPDNLVGKLGSLEAEAIERL
                     RPPPVPHRRGPVRLDDGDRRLLALLATDGRAGFEQLASATGWSPTTVRRRMTELREHGL
                     LYLDIDVDWRMFGVNARTLLWLSVAPAHLEEAGQALAGHPEIAFAAATTGPTNLYASVV
                     CTNQQELYRYLTTRVAALPAITHVETAPVIRTVKQAGNQT"
     gene            14587..16023
                     /locus_tag="GR130_RS16065"
                     /old_locus_tag="GR130_16065"
     CDS             14587..16023
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014059007.1"
                     /locus_tag="GR130_RS16065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_16065"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_159505376.1"
                     /transl_table=11
                     /translation="MDTDVLIVGAGPTGMTLANELLMAGVSTVLVDRLSQRSDLSKAGG
                     VQSRTLEALDQRGLLEPLLATGDHPVTTGHFAGIPLPLHSNRHRLPWRSVPQVVIEGFF
                     ERHLAAHGLHARRDHELVGLAQDDNGVTATFANGATLRSRHLVAADGAHSTVRSLLGAA
                     FPGQPGTLTITAADVRLGGVDPSTSHTWNEDGHWAAVFPLGTDPQGRQLRRLVLGGPGR
                     SLPREVPVTEDEIRHGLNTVFGTRVHLHELRYARRITNASRQVERYRHGRVFLAGDAAH
                     VHLPLGAQGMNTGMQDALNLGWKLGAAVHGWAPENLLDTYHAERHPAGAAVLRNVRAQS
                     LLMDWAGTRDPDVLAAREVFTAMAQLPDVQHHLADLMSGMAIRYPMPGTETHPLVGRPA
                     PDLGLGPARVHELLRSGRGVLLDPADTFAGVAGPWSDRVDRAGQGADTEPMLIRPDGYV
                     CWAGADDLEPALARWFGEPR"
     gene            complement(16285..16659)
                     /locus_tag="GR130_RS16070"
                     /old_locus_tag="GR130_16070"
     CDS             complement(16285..16659)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018385901.1"
                     /locus_tag="GR130_RS16070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_16070"
                     /product="DoxX family protein"
                     /protein_id="WP_159505377.1"
                     /transl_table=11
                     /translation="MNTLLWVLTGLLAVLFLAAGAAKLLQPKEKVVATSGAWAADYSPG
                     AIKAIGLLEILGALGTVLPAAVDTAVGLVPAAATGLGLLMIGAGAVHARRGEGRNVAVN
                     ALLLAMAAVVAWGRFGPYAF"
     misc_feature    16704..16717
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.37"
                     /tool="antismash"
     gene            16765..17019
                     /locus_tag="GR130_RS40500"
     CDS             16765..17019
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GR130_RS40500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_236573051.1"
                     /transl_table=11
                     /translation="MSKDEPRWLSASELDAWKAFSAMLIKLPAALDAQLRSDAGLNQFE
                     YLVLAALSDAPERTLRMSELAVLANGSLSRLSHVVKRLE"
     CDS             complement(17091..17309)
                     /gene="allorf_3674152_3674370"
                     /locus_tag="allorf_3674152_3674370"
                     /protein_id="allorf_3674152_3674370"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MPRCDAEYPAGRDGHRSIAGQWRSGQARSGSIPWRICREIRRSCS
                     ICSGSSGSRTSDRTCWTWPGALSASFR"
     CDS_motif       complement(17250..17309)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MPRCDAEYPAGRDGHRSIAG"
                     /locus_tag="allorf_3674152_3674370_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(17091..17249)
                     /prepeptide="core"
                     /locus_tag="allorf_3674152_3674370_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.10"
                     /molecular_weight="5565.2"
                     /monoisotopic_mass="5561.8"
                     /core_sequence="QWRSGQARSGSIPWRICREIRRSCSICSGSSGSRTSDRTCWTW
                     PGALSASFR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPRCDAEYPAGRDGHRSIAG"
                     /leader_location="[17249:17309](-)"
                     /alternative_weights="5583.2"
                     /alternative_weights="5601.2"
                     /alternative_weights="5619.2"
                     /alternative_weights="5637.3"
                     /alternative_weights="5655.3"
                     /alternative_weights="5673.3"
                     /alternative_weights="5691.3"
                     /alternative_weights="5709.3"
                     /alternative_weights="5727.4"
                     /alternative_weights="5745.4"
                     /alternative_weights="5763.4"
     CDS             complement(17325..17510)
                     /gene="allorf_3674386_3674571"
                     /locus_tag="allorf_3674386_3674571"
                     /protein_id="allorf_3674386_3674571"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MTTDAAVAPSCTRRGTRRRGDSACSRADTPGSERLVLARSPCPPP
                     WSVCRAEGPEGVDAAV"
     CDS_motif       complement(17415..17510)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MTTDAAVAPSCTRRGTRRRGDSACSRADTPGS"
                     /locus_tag="allorf_3674386_3674571_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(17325..17414)
                     /prepeptide="core"
                     /locus_tag="allorf_3674386_3674571_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.90"
                     /molecular_weight="3026.4"
                     /monoisotopic_mass="3024.5"
                     /core_sequence="ERLVLARSPCPPPWSVCRAEGPEGVDAAV"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTTDAAVAPSCTRRGTRRRGDSACSRADTPGS"
                     /leader_location="[17414:17510](-)"
     gene            complement(17507..17947)
                     /locus_tag="GR130_RS16080"
                     /old_locus_tag="GR130_16080"
     CDS             complement(17507..17947)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016577420.1"
                     /locus_tag="GR130_RS16080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_16080"
                     /product="tautomerase family protein"
                     /protein_id="WP_159505378.1"
                     /transl_table=11
                     /translation="MPLVRIDALRADSNRLGALGRAVHDALIETIGIPPDDHFQILVSH
                     DGTNSTLHYGGYFDIDRDDDIVYVAITLRSGRTSEQKQALYRRIADLAHAYAGTAPRNV
                     FVTLTENASIDWSLGNGEAQYVTSPPAADGTPSPAAGTATRT"
     misc_feature    complement(18103..18116)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.41"
                     /tool="antismash"
     misc_feature    complement(18245..18258)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 20.2"
                     /tool="antismash"
     misc_feature    complement(18337..18353)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.65"
                     /tool="antismash"
     gene            18533..19990
                     /locus_tag="GR130_RS16085"
                     /old_locus_tag="GR130_16085"
     CDS             18533..19990
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606619.1"
                     /locus_tag="GR130_RS16085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_16085"
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="WP_236573052.1"
                     /transl_table=11
                     /translation="MPSNGSTFTRATAGRSANAPRWGGGRDLTRYLCAAAYLHREYARS
                     LIREIAAEPHLGVAMAPACDVPVVLRHAYRANARRHSRDLLLAALFVLAVVFTFWAGRP
                     QATLLMLLFAWVTVFSFELSTKYGRHLQGLRPGRFDPAAAPPPLNPEIAAGLRQIGDYA
                     QGNVTAYSGYSPFIGYGNELESWSLTFDVTTSSGAGVTARDFDVKDLYAHIAQRVGALS
                     LPCLEIEERLFVDGATLLGDRRFLPDPLGRPVASIPQDRMDELKRAPEEGARPYLVVHS
                     TGWGGELVTSLFLRFFRSDSNLYVEAVQTVLCPLLDRYRVIDTLMPRPPVRDVLELLAQ
                     TLVSTVFVLFASPVRAVAGFSPDYWMFWRLRRQYKLITQLRNFDYGARQSVRQKAADGR
                     HRRYFQKADCGMVLKTVEKRVLDALVEFAEARGIDVSELVQRQEIIINNGIIATQGAKV
                     ESSSVATGEKSRVSMNILNKIPLVRLD"
     gene            20016..20387
                     /locus_tag="GR130_RS16090"
                     /old_locus_tag="GR130_16090"
     CDS             20016..20387
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606620.1"
                     /locus_tag="GR130_RS16090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_16090"
                     /product="hypothetical protein"
                     /protein_id="WP_159505379.1"
                     /transl_table=11
                     /translation="MRRNDGIIATGGSNVVGNAVASGRGARAEVQNSGLSQGDGGRQPS
                     AQEIGDLLSRLIDELGRSDHPDRGDLIEAAEDAREEVTAEAPRKGKLKLFAKGLVEAVP
                     GFTALASLAVTIEEAIRGL"
     gene            20523..21221
                     /locus_tag="GR130_RS16095"
                     /old_locus_tag="GR130_16095"
     CDS             20523..21221
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088942.1"
                     /locus_tag="GR130_RS16095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_16095"
                     /product="hypothetical protein"
                     /protein_id="WP_201304897.1"
                     /transl_table=11
                     /translation="MPSCLRCGADLGGTAATRCPRCGTPCRDGTWHGTYQPRAAADDDY
                     VRVGPTILPRWMPWLLAAVLVGGGAATYLLLHSPSDPSPRTVDATPWTTPPPAPGAAPV
                     TPGYGDTPTVPYTPTVPYTPPDALVPSAASPPDDAGAVVEQFYRDINDHDFAAAWKLGG
                     RNIGGASYQDWQAGYATTAHIEVGVVDTEGAGQVTAVINATQTDGSTKVFRGTYTVSGG
                     AIVSADITQR"
     misc_feature    20535..20537
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(21244..22341)
                     /locus_tag="GR130_RS16100"
                     /old_locus_tag="GR130_16100"
     CDS             complement(21244..22341)
                     /NRPS_PKS="Domain: PKS_ER (24-354). E-value: 8.4e-10.
                     Score: 30.2. Matches aSDomain:
                     nrpspksdomains_GR130_RS16100_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018540700.1"
                     /locus_tag="GR130_RS16100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_16100"
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="WP_159505380.1"
                     /sec_met_domain="ADH_N (E-value: 1.2e-21, bitscore: 75.5,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 9.7e-27, bitscore:
                     92.4, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIQAALVESPGGPFTVHDDLVIAAPRPDEILVRMTAAGICHTDL
                     SARRSWPAERSPMVFGHEGAGVVEAVGEEVDTVRPGDSVALSYRSCTTCGQCSARHPAY
                     CETGIFALNASGARPDGTTPLSRANGDTVFGNFFGQSAFASHAIAHRSNVVKVPADLPP
                     AIAAPLGCGVQTGVGTVLNVLRPPKGSSVAVFGTGSVGLSSVMAAVAEGCDVIAVDPLP
                     ARRAKALEFGATAAVDPTTDDVAEAVRDLTGGGPHHAIDTTGQAEVISQAVTALRRQGT
                     LALVGIGGQATFDIMTVMTKGLRIRGVIEGDARPAEFIPHLVALHREGTLPLHDIITEF
                     PFAEIERAAQAASAGQVIKPVLRFG"
     aSDomain        complement(21280..22269)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GR130_RS16100_PKS_ER.1"
                     /evalue="8.40E-10"
                     /label="GR130_RS16100_PKS_ER.1"
                     /locus_tag="GR130_RS16100"
                     /protein_end="354"
                     /protein_start="24"
                     /score="30.2"
                     /tool="antismash"
                     /translation="APRPDEILVRMTAAGICHTDLSARRSWPAERSPMVFGHEGAGVVE
                     AVGEEVDTVRPGDSVALSYRSCTTCGQCSARHPAYCETGIFALNASGARPDGTTPLSRA
                     NGDTVFGNFFGQSAFASHAIAHRSNVVKVPADLPPAIAAPLGCGVQTGVGTVLNVLRPP
                     KGSSVAVFGTGSVGLSSVMAAVAEGCDVIAVDPLPARRAKALEFGATAAVDPTTDDVAE
                     AVRDLTGGGPHHAIDTTGQAEVISQAVTALRRQGTLALVGIGGQATFDIMTVMTKGLRI
                     RGVIEGDARPAEFIPHLVALHREGTLPLHDIITEFPFAEIERAAQAASA"
     CDS_motif       complement(21793..21813)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GR130_RS16100_0002"
                     /evalue="7.90E+01"
                     /label="PKSI-ER_m2"
                     /locus_tag="GR130_RS16100"
                     /protein_end="183"
                     /protein_start="176"
                     /score="-2.7"
                     /tool="antismash"
                     /translation="VGTVLNV"
     CDS_motif       complement(22126..22164)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GR130_RS16100_0001"
                     /evalue="3.90E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="GR130_RS16100"
                     /protein_end="72"
                     /protein_start="59"
                     /score="10.3"
                     /tool="antismash"
                     /translation="FGHEGAGVVEAVG"
ORIGIN
        1 ccgtattcgc cgccaccgtc aggatcgacc gtagctgcgc aatgatgtcc agccggttcc
       61 gcacgaactg aggatccgtg atctttccgg tcgccggatc ggtgttgccc gcgccgaacc
      121 ggagcaccgg tgtgtgcacg tgcccgcctg gcagcgtgtc gtggaggccc agccggtcgc
      181 gcagcagggt cgcgcggtag gcgatctcat tggagaggta gttgccgccg ccgccctcac
      241 gggccgttga gcccggggtg gggccgtcgg ggcggacgac gggttcggtg ctccctgccg
      301 ggatctcggt gacctcggtg tggtcgtagc ccgggaaccg gccggtgtgc gcggtcacga
      361 tcgctttgga ggggagggtg gtcgtcgtcc actgcggctg tgtggccggg gcggcgaccg
      421 ggaccgtccc agtgctgctg gtgttgtcgt tgtcggggta gccgccgcgc caggccccgt
      481 tcgtccgctc gacgtcgaag cggcccaccc ggccctggct caccgtcgtg tacaggtcga
      541 ccttcggcag gtacggcgcc agcgtccgct ccaccgtccc cgccgcgaag tcctgccagc
      601 gcaccgggaa cgtgacggcc tcgatgcggg ccggaccgga gtcggtctgg atcaccgtcc
      661 cgtcgagagc gagcgcgacg gccccggacg ggttggagat cctgatgtcc tggtccagtg
      721 tgaacgggtc gaagccggtg acgagaatgc gcttgacgcc cgtggcgcgc gacgggtagc
      781 ggatgtcggt ctggccgcgc gaggtccgct ccaactggtc gagcagggcc gaacgttgcg
      841 cgtcactgag cccgaaacgc ggctcccacg tgcgcacgtc ccgcgtcatc ccgagccgcg
      901 cccagtacag cggccggtcg tcgtcccggc tgaggtcgcc gcccgcgggg ccccgtccgt
      961 gcgcccggtc gacggcgcgc cgccacagcg ccgtaccgtc ccgaacgacg atgccgcggg
     1021 cctgctcaaa ggagtgcgtc cgggtcaggt cgcggacgaa gtccggggcc acggagtcga
     1081 aaccggagcg tcgcagtatc tcctgcggtg ccgccttgtc gaggcgctgc tcctcgacgg
     1141 tcggggccgg ggcgccctga gcggcccgag ccgccgccgt ggtcgcgggt gccaccagcc
     1201 ccgccagcag ggccataccg aggatgccga tccgaacacg tagggaattc aaggggcttg
     1261 gggtccttcc gtcgctgtgg gggcgcgcgt actgccggac cgctgcagta tcgcgtgacg
     1321 gaagtggtct acgccatggg tgtggctcag gggcctcgaa ctcatacggc aaccagcaga
     1381 gatggcccgc cttcaccatc accatcacca tcaccggcac ctcgacggtg agttccgccc
     1441 ttgaacgtcg gcgctccagc ggcgaggcgg ctcgtgccga ggccgcggtc gcgcggcacg
     1501 aggacgacgt cccggccgtg ccggtggccg tggctccggt cgtgctgccc gcgccccgcc
     1561 cggccgcgcg gagtgacggc cgaggtggtc aacgcccacg ggcaggtcat cgggcaggcc
     1621 cacgccgaac ccggacggcc cccaggagcg gacagggccg ccgaggcgct gaccgcggtc
     1681 gccgcccggc tccggtcaca gtgcgcgggc ggactccgga gcgcggtggt cagcgccgcc
     1741 gaccccgtgg accgcaccac cggtcggctc gtccaaccgc gtcgaccgcc atcgatgccg
     1801 cggccctgcg gtcggcgacc gcaggcgacg acgagccggc gcaccggaga cgggcgggag
     1861 tcagcacctg cggccccggt gcaattccag ccgctggccc gggaagcgtt cgcggaagcc
     1921 gcggtcgtgt gagacggcga ccaccgctcc cgggtatgcc gcgagcgccg cctccaggtc
     1981 ctcgaccagg tcgagcgcga ggtggttcgt cggctcgtcg aggacgagga ggtccgcggg
     2041 ccgggtcacc aggcgcgcga tctgcagccg ccgctgctgc cctgcggaca ggtccgcgac
     2101 cgggatgtgc aggtcctcct ggcggaacag gcccagcgcc agcagttgtt cggcgtgctc
     2161 ctccggcagt ccgggacgcc tggccgcgaa ggcggcgagc agcgggagcc gtgtggagcg
     2221 cgcgggcagc tcctgcgcca ggtacccgat ccgggcgggg cggcgtaccg cgccggcgtc
     2281 cggttccagt tcgccggcca ggaggcgcag cagagtggtc ttgcccgccc cgttcccgcc
     2341 ggtgaccagc agccgctgcc cgggcgcgat cgccagcagc ccgtccaggc gcagccgttc
     2401 gccgaccgcc acgccgtcga gctcggcaag ggggcatccg tggcccgagc gaagcccgga
     2461 gcttggggaa gggcggtcgg caggaggctc gccgcccgcc gcgggcagcg cggcggtgaa
     2521 ccgcagcggt tgtggcggcg ccgccaccgg attgcgctgc agatgggcca gtcgctcccg
     2581 ggctgcccgc acctgcccgc cgagcttggc ctcgtgagag cggcggtgct tgccgaagcc
     2641 ctgccgcggg tccttgccgg tgccggccag ccgcttcccg gcggcttcga gcagctcctc
     2701 ggtacgggcc atctcctgaa gccagtccgc gtatccctgt tccgcgcggc gtcgggcggt
     2761 ggccttcgcg gcgcggtagc cggcccagcc gtcgccgtaa cggcgcaccg tgcgcgcctc
     2821 ccggtcgacc tcgaggatgg tggtggcgat gcgctgaagg aagccgcggt cgtgggtgac
     2881 ggcgacgacg gtgccgcggt gcgcgcgcag atgctcctca agccagcgca cggccgcgtc
     2941 gtcgaggtgg ttcgtcggct cgtccaggag cagcagctcg ggggcggcgg ccagcacgca
     3001 ggcgagcgcc agccgcgact gctcaccgcc ggagagcgag ccgagcacgc ggtcgcgggt
     3061 gatcccggcg agcccgagcc cgtgcatcgc ggcctcgacg cgggcgtccg cctcgtatcc
     3121 gccgcgttct tcgtacgcga tcagcagctc accgtacgcg gcgagttcgt ccttcgacgc
     3181 ctcgccgagg cgctgttccg ccgtgcgcag ccggcgctcc atggcgcgca gttcggccag
     3241 ggcgaggtcg acggtgtcct gcacggtgcg gtgaggggcg aggtcgaggg tctgggcgag
     3301 gtggccggtg ccgccgggga tgctgacggt gatctccccg acgtccggca gctcggccgc
     3361 ggcgagcagc cgcagcaggg tggacttgcc ggagccgttc tcgccgatga cggcggcctt
     3421 ctcgcccggg cggacggtga aggagacctg gtcgaggacg gtccgggtgt cgtaggactt
     3481 ggtgacgtcc ttgacggaca gctgcgcaac ggcagcgggc acggcggtat gggcgcgttc
     3541 gcgcatggac tttccctggg aatgcgaagg gtcaacgggc ggcagaaacg gcggcgtcgg
     3601 ccgtgcccgg actcagagaa agtagaagaa agccatgccc ccaccatagc aagacgatgc
     3661 gtctcgtcgc ttctcgtgta tgtcgcgaag cccgtgatcc gcaccacccg cccgagcctg
     3721 ccgcccctag aggcgaccaa tggggccacc gacctgcacg acgaacccgt ggcccatccc
     3781 ggcacgtccg aggctggcgc ctcgtggacc cgagcctgca ccgcgcaggc cgcgatgccc
     3841 tgctgggtgc gcaggtgctc gataccgtcg agcaggtccc gcttgtacgg ggcgtgcagg
     3901 agggcgacgg cttggtggtg ggccgtagag gttctcggcc cacacggcgg cgggcggcgt
     3961 ccgcccgggt cgcgtctagg aaccggggcc tggtgcactt catggctgtg gactggctgt
     4021 gtatgcgcat ggcccggggc gtcgaccggc ccgggccatg caggtgctgg ttgatcagta
     4081 ctggatggtg tggttgtaga ggatgtttcg ggccttggcg ccggtgtcca ggccgtagtc
     4141 gggccggtcg gtgacgaagt actcgcggaa actggactgc tgggtcttgg tcatcatggt
     4201 gttgctcttg gaccagccgc cgtcgacctg ggaccacagg tcgaccagcg cggtggcgac
     4261 gcgggcctcg caggcgtcgc cagggtcgat gccggtcgtg gagcggtcgt tggcgagatt
     4321 ctgggagctg ccgttgcccc agtagtaggt ggtgtcgttg aacgtgtgga acgccaccgc
     4381 gttggcgaag ccctcggtcc agccgcaact ggtggaggag gtgcggctga cgtagtgggg
     4441 cgagcagttg gtcacgttcg gccaccagcc cttgtagagc ttgcccatga gggcgtggcc
     4501 cgattcgtgg acgacggtgt gctcggagtc ggggtcgttg tccgcgaggt ggatcttgtc
     4561 ctcgttggtc gaccagtagg tgccgtcggt ggagccgggg taccactgga cggtgatcgg
     4621 ggtgcagtgg ccgtcctgct gactgctggc ccagcagttg gtggtggaac cgcggttcca
     4681 ccacagcttg ttgagggtgt cgagggcgtg ccaggcgcgg ctctgccctt cgttggcgta
     4741 cacgttgccc aggcgggtgc tgcccgagac gttgtcctgc gagtaggtgg cagtggtgta
     4801 gaggcggccg ttgccgtcga ccacggacca cgactggcct gcctgggtcc ggaactccac
     4861 ccagaccttg gaggtgacgg aggtggtggg ggtgtagcag aggttgaagc tgccgtcttt
     4921 gttgccggtc attcccgtgg cgagcttctg cgtaccgctg ttggcggtgg gctggcccca
     4981 cagggtgacg ttggcgttgt ggaccggctc gtcccggttt gccttgctgt tccaactacc
     5041 gccctcggcg gactggaagc ggttgcggaa ggtgccgctg atacagacct gcgaggagtc
     5101 cccggcccgg ccgcctgtgc gcggggcggc cggggcggag gcggctgagg cgcggtccgg
     5161 ggcgggtgcc tcgggggtga ccggccgttc cttgcgagcg ccgggcgtgg ggtgatggac
     5221 cggggccggg tgggccttgg tgaccgatat gcccttgtcg gaggagccgt tggtcttgct
     5281 gacggtgagt tcgaccgagt cgtgtccggc gcggcgcggg tcggggtggt cgacgtcgct
     5341 gatgtccgcc tggatctggg cgggtccggc ggcgaccgcc ttgaccttga gactgacggt
     5401 ccgggtgccg ggggtgaggg caaggatgcg gctggtgcgc tggccgaagg tgtccgtggc
     5461 gggcgcggtg aggccggagc cttcgccgtc ggatatccgg agtgcgggcg gcagttggag
     5521 ggacaggccg gcgcgcttga cgtcggtctg ggccttgacg ttcaccgtga gggtggcctg
     5581 ctcgccgacg gcagggaggt ggtcgaggga agcggtgacg ccgagacagc tcagcggtgc
     5641 ctcggagttc ttctccgcag ggcggatcgt gcaggtgccg gccggtgtgg gggcgtgggc
     5701 ctgaggggag ttgcccgcga acgcggacgg cactacggcg gctgccaggc agacgcctgc
     5761 gcctgccatc gcggtcagag cggcagatct gggaacccgt ttccgggacc gtattcggga
     5821 catggcatgc cttcctacgg gcgtgcacag ccgacttcgg tgcacgccga caaagcgtga
     5881 ggggggtaag gcaccgactc aggggcacta cagccatcaa tcgttggcca tagctgcacc
     5941 ttaggtaacg gtggccggaa cgatatacct caccgcttgc acatgtcact gccgtgggag
     6001 aagagaacga ggcacaggaa gagaggggtt ggcggatgct cggttgtcac cggactcatc
     6061 tgacggcggc gcgacgtaca gagaactact gcgcgtcgat gccggcgagc tgaggcgatc
     6121 tgccgttgca gcacggcctg ttggcgtcgc caacagcgag gcgccgcggc tctgcctttc
     6181 ggcggatcgc tgacccagtc cctgagagga agacttcagc ggcatagggg ctgccacaga
     6241 acctcactca tcatggcccg tgccctgacc ttcccctctc gatatgccgt cgcggcagga
     6301 agtggctgca ctatgcgctc ttaccatcgc gccatggccc ggaaagtcgt caccctctac
     6361 acggatgacc gcacgggtga agcaacctcg aaggtcacca cccacacctt cagcctcaac
     6421 ggtgtgcagt accagattga tgtggctccc gacggctacg acctgctgct tgaggcgatg
     6481 gcccccttca ccaaggcagg gcgaaagacc ggcaggaccc gcgagtccct caaggccacc
     6541 gccgccggcc ctgacgacgg cgccgccatc cgcgcatggt ccaagggagc gggctatgag
     6601 gtcagcaacc acggcagggt accggccgag gcgcgcgaag cgtacgacaa gacccactga
     6661 cctcctccta cagcgggaag cccctcacag ttcggtgagg ggcttccggg tttgaacgga
     6721 cgacatgcac acgcagcgca ttgggcggat ccggtactta gcaggccgag ttaccggttt
     6781 gcggcgaccg cagcgtggcg aggccggcag acgcgagtag cagtgaaccg ccgccgatga
     6841 cgaaggacag cggggggtcc gcgtggtaca gcggcagcag ggcgatgggg gccatcgccg
     6901 cgccgccgaa gcggaaggcg gagaccgctg agagcgcgcc gccccggttg tcgggcacct
     6961 cgcggacggt gaggttctgc aggcacacgt tgagcatcga gtaggcgatg cccgcgcccg
     7021 tccagcacag caccagcgcc ggcaggctgt gcgtcgatcc ggtcagcgcg accagcaccg
     7081 cccccagcgc ggcggcgatc ccaccgcagc ggcgcgcgcc gaagcggtca ccgagcgaac
     7141 cccaactcgc ccccagcagc aacccggtca agccgaagcc cagcagcgcg accccggtga
     7201 ggtctgggcg gatgccgagg tgctcttcgg cgtgcaggga gaccatgaac ggcagcccgg
     7261 ccgcgccgaa gtagctgacg aacgcggcca ccgacagcag ccccatgcgt gcgttcacca
     7321 gggggcgcag gcgcggggcc tgcgcacccg gccgggcgcc gccgggtggg ggtgccagcg
     7381 cgaggagccc ggccgcggcg gcgacaccga cgaacgccca gcgccagttc gccgccgcgg
     7441 ccacaccgcc gagcagtggc gagagcgact ggccggcggc ctggcaactg gccagcagtc
     7501 ccacggaccg gctcagtcgg tgcgctggaa ccatgtcggc cagcccggac agcagcagcg
     7561 gcgagacgaa cgcgttggcg gtgcccatca ccgcccgtac caccagcagc agcgcgatgt
     7621 tcggtgcgat ggcgccgagc agcgaggcga tcaggtagac caggtaggca agcagcacgg
     7681 tgcgtcggcg gccccaccgc tcgcccacgg tcccggacac cagttgcacc agggcgaacg
     7741 ggacgaagta ggcggtgacc gtcagcgtgg tggcgctcgt cgaggcgttg agcgagtcgg
     7801 cgatctgcgg cagcatcggt gccaccacgc cgccgcccag cggcccgagc gcagcgccgg
     7861 catacaccgc gaaaacgcgt aacctccggc ccggtccgct gctcccgggc cgggcctgcg
     7921 cacgcgctgc ggaccgggtt ggacccggcg ggtcgaccgg tgtgcccagc tcggtgtttc
     7981 ccacggcgcc acgcggcgcg tggtcgtcag tcatcacggt ctctttccac gtagagcgga
     8041 ttggcccgtg agcgacgcta ggttctccgc gtcgtgtctg ggtaatgcct gtcatggaac
     8101 accgatatcc ggcaggcata gtgcgacgtg agcggaccgc gtcagcggtg tactgcggcg
     8161 atcgccacat cgatgaaacg gcgcagcagg agctcctgca tgtgcggcag gtaggcgagt
     8221 tcgaccggga ccggaggcgc gttgaccagc ggaacgaagg tcaccccggg gtggttgatc
     8281 cggcgcaccc ccactgtcgg ggccaccccg atgcctcggt tggcggccac cgactcgacc
     8341 cactcgtcgt agttggtcgt ctcgatcacg tctcgcggcc ccttgccggg agcccaggac
     8401 cagtggccgg tcgcgccgct gaccacgttc tccaccagcg gccaccgggg aacgtctccc
     8461 cagtggacct cgtcgagtcg gctcacctcg gacttggcgg cgcaggcgac cgccgcccgc
     8521 ggttcgtcga acaggtgcac cgtcttgacc ggcgcggacg aacgcacgcc accgcgcacc
     8581 agcgcgacat cgatcacatg acgttgcagt gcctgaatcg gatcgtcggt gcgcatgagg
     8641 ttcaccgtgc tccccgaggt tcgctcgaac tcgctgatgg tgcgctgagc ccacgggtca
     8701 ggcatcaacc agctgaatcc cagccggatg ctgacctgtt cactcaacgc gttcatcgcc
     8761 cggtccagct cgttgagcac ccgttccacc tgtgcgagga aggagttgcc cacgttggtg
     8821 agttccacgt gccgggagct tcggttgaac aaccgcaccc gcaacgcggt ctccaactgc
     8881 tgaacggtgc gggtcaatgc cggctgggtg atggtcagtt tctcggcggc acgggtgaat
     8941 gactgctgtc gcgccaccgc gacgaacgcg cgcagatgac gcagctcgac atccatgact
     9001 atggagcata gcccgagcgc acaaggcatt tctcatgttc gaacggactg gctacgttcg
     9061 gggtgcgggc ggctggggca gatcagtgaa cgcagcaacg cccacccggt cgatgccgta
     9121 cagcacacca ggtttcgggc gaggtgcgtg tgcgtcggcg gtgagtctgg gggtgggccg
     9181 gttcgtctgc ccgcgagtct ggcgccgatc catgtccggt ccgggcttcg cgcgcgggcg
     9241 gctgccgaca cgcaccaccg gcacgatgca gaggcggcaa ccgcggggtc ggggggcggg
     9301 gtccggcccc cttcctgacc gcaccgaaag gtgtccggct cgggtcgaag ttcccgggga
     9361 ccgaagagaa cgaggagtaa gcagcatggc caagggatgt aaaggatatc tggtcggcac
     9421 ctaccgatcg gtgcgcgacc cggaaaagct cgccgcgtac ggggagttgg ccaagcccgc
     9481 gctggaggcg gccggcggac ggattatggc ccggggcggc cgggtgaccg cgttcgagtc
     9541 gggcctgccc gagcgcacgg tcctggtcga gttccccagc tacgatgccg cggtcgcggc
     9601 ctacttaagc gaggactacc agcaggccgt cgcggtgctg gacgatggtg ccgaccgcga
     9661 tgtacgggtc gtggaggggc ttgactgagc gccccgacac ccgtgtggtc cccgccggca
     9721 acggcgggga ccctgcacga gatccatccc ctgaatcgcc gaacggtcaa ggcgacgcgt
     9781 cgagttccca tccccatccc catcctcact ccgcccgtcc tggtcggcgt gttgctgcga
     9841 gtacatcgac cgcttcggca gagcggcatg gctgcctgct ccacaaggca gcaggccagt
     9901 tgccccggat cggctcgtgc cgccgtgtcc gcaaagtccc gtctgccgtt cggcgcccgg
     9961 cacgcactcc gggcgaacga cgggacttcg cgggcacgac ctagcagagg aaggcggtcg
    10021 gggccccgtt gggcagctca ggggtgttga gcatcaagtc gctgtccgcg acacccgccc
    10081 aaccgagcat gtagccgacg agcgaggtgt gccccggcgc tccgacgtag aagccggtct
    10141 gccgggcctg cgccagtacc cggtgctggt aggaccgtgc caggtcgatc agcgtcgggt
    10201 cgtccagatg gcgggaggcg gcgagcaggc actggatcac cccggcggtt ccgtggcaca
    10261 ccgacaggtc caccggccgg tcgtcgggca acgcgacagc ggcctgcgcc aggcgttccg
    10321 catgcgcacg cacgaggtcg tcgagcccgg tgcgacggcc gatctcgccg gccgcgagga
    10381 ggagaccggc ggcgccgttg caccagcccg cgagcgtcgg ccgacagtcc ggcaggtggc
    10441 gttccagcca ctcggcggcc tcccgccgcc actgcccatg ggacatcagt cgcccggccc
    10501 gggctttggc ccacatcacg ccgagctgtc cgtgcgcgac ttcccaaccg gcgcccttgg
    10561 gccggggccc gtgcggatcg aaggccgtgc gcgccagagc gtccagagac gcggcacgca
    10621 ccgggatacc gctctccatg cgggacagca gcagcatcag ggggccggcc ggcccgttgg
    10681 acagatcgcc ctcgcggtcc tcgccccgct tggcgatctt ttcgagcagg gtgtccagcc
    10741 aggcgtcgtc gatcgcatcg ggcatcgaca gcagttgtga cgcgaatccg gagaacactg
    10801 attccgggag ggcgtccaac tgctcgccgt acgtgtcggt gagttcacgg aggccgacct
    10861 cggcggcatg cgccgtgctg tggcgcccgg ccgatgccac cgcgcgtcga atacctccca
    10921 tgtcgtggaa ggccacgtgg ttgcccggat tgatggtggg cgtatggcgg tccgggccga
    10981 tactgccgat ccatccggca ccggcaccgg cgccgtgctc gggctcgttg ccactggtga
    11041 ccgccagatc gccgatcacc tcggcgatcc gcccgcccca ggtgccggga ccggccggta
    11101 cgagggtggg gccgaagacc gaatgccgcc acaatccgcc ggcatcgggg gcgatgtggc
    11161 cgaggcactc ctcgatcagg aaccggtgga acctgtcgtg gcgctctcgt gccatggcaa
    11221 gtccccggcg ggccgtggcg aggggagagc ggtggaacaa cggccacggc tcgccaccgt
    11281 acgcacagac gtcggtgtcg ccggcgagtg tggtgaagta cgggatgtca ccggcgtcca
    11341 gggccgcgtg ctcggcggcg gccagcgcat cgttctgttc cggcgtcagc gtcttgtgga
    11401 accgccggag cagaccgaac aaccggcggg tttcgttctc gtcgcgcaga tacgtcgggt
    11461 gggtggaggc gtccaggtag cgggcgtaga cctccgtcgc ccgtatgagg caccgcaccg
    11521 gcatgtccgc gaagcggtcc agtaccgcgt cgatcgcgcc ggaccgcacg cattccaggg
    11581 catcccgata gccgctcatc acgtcgacga agtagtcgcc gatggcgagc tgttcgccct
    11641 tcagagacgg gacgttgtcg gaatgccggt gggtgaacgt ccgccattcg acccgaatgc
    11701 cgtcgctctc ggggtccacg accgtcgggt tcttcagcga cgacctctgc tcaccgagca
    11761 cgccgacacc ggcaagcatc acgtcgatca cggagtgcgg gttattgacc ggcagcagca
    11821 gcgtggacgc cggcgagagc ctcgtctgct ccaccagcgt gtcggtgagc gtgtccttca
    11881 tggcggcgcc gaagtgggcg cgcagcaggg tctcggtatc gaccacgcag gggaactcgc
    11941 cgcaggcgag caggttttcg tcgtgcaggt cggtggcgcc gagagcgccg aacaagcaga
    12001 tcagagcccc gagacggtag aaatagcgcc ccgcctgcgc gtcggaggtc atgggcttac
    12061 cggccaacat cgcctgccag ccgtgtccgc ccggcgagat cgacgcggga acgcaaccgg
    12121 agaggctgtg ttgcacatac ggctcggcgg cctcgaacac ggcatgggcg aacgcgtccc
    12181 cggccagcgg cctcggcttg tagaccagct gcgcgcccga ggtggtggtg acgaaaacga
    12241 cccgctgatt gccgttgtgc gggtcggagt tcgacagact cacttcccgg atcgtctcct
    12301 gcgccccgat tccggcgatg tcggtcaatt gcgcacggtc gtcgcggaaa gcggcgagca
    12361 tcctcgcgta cgcctttcgc aggttttccg tgatcctcgc caggcggcgc cgcaacaccg
    12421 gatacgcatc caagatcgcc tcgcaggtgt ccggatgacg cagggcgagg cggaacgcgt
    12481 cgatgccgat gctgctgtcg ggatccaggg ggaggccgcg ccctgcacgg aagtggtgga
    12541 agcgctctat caacgtgcgg tagctatggt cctccacgac atgcaacgcc acctgccaca
    12601 acttggcggt gaccttctca cggtcctcct cggccacggt cgcggcgagt tgcggcgcca
    12661 ggttctccgt gaacgtctcc agcggaagga cgtactgata gaagggaagg aacgcctgca
    12721 cacccagagt cggattgctc atgctcgctc gccaatcaga ggagaaccgg cgcccgcctt
    12781 cggaacacgg tgacgcgccc ggttgtcgac cagtttccgg tggggaccgt gccggatttc
    12841 cgggcggaga atccgtggag aagtcgcaat gcggtacccc attgcgtgca gatacgagac
    12901 aatgcgatcc gacccggcgg ggtgagggtc acgatccgac cctcaccccg ccgggcggtc
    12961 atgccgcagc tatctgggca acgatgtcat tgctcagtcg cggaaacaga agctgaagct
    13021 gcacccgatc tggctggcat tgggggccga ctcctgctcc ggctcctggc tcatctcgat
    13081 gagctgagtc tcgtcgtacg tacccagaag atcatcgctc atggcagttc atctcccttt
    13141 gtgtggtagg tgcttactct gtgaccttga cagggggcgg tgaaatgtcg atgaaatctc
    13201 gatagtgcgc cacatctcgg gcttcatcgg cggcgtgccc catgagagct gcgcaccggc
    13261 cggcaggatc gtcatggccc cgcggcgccg acgccacgct gttgtgccgg cacgactcca
    13321 ccgtcggccg ctcccgggcg gggcgcgtct ttgaggggcc gctggggccg atacgacccc
    13381 gacggccgga ccgaggacct gccacccgac cgcgaaacgc acgagatgcg ccgacccggc
    13441 acaagcagtg tccggtacca gcagtgtgct gtgcgcgatc gaaacggcag ggggctggtc
    13501 ggctgctatg tctggttccc tgcctgcttg acggtcctga tcaccggtgc cgtttcgacg
    13561 tgtgtgatgg ccgggagtgc ggcgacccgc gtggtcaggt accggtacag ctcctgttgg
    13621 ttcgtgcaca ccacgctcgc gtacaggttg gtcgggccgg tcgtggcggc ggcgaacgcg
    13681 atctccggat gcccggccag tgcctgaccg gcctcctcca ggtgtgcggg ggcgaccgag
    13741 agccagagca gggttcgggc gttcacgccg aacatgcgcc agtcgacgtc gatgtcgaga
    13801 tagagcaggc cgtgttcgcg cagctccgtc atccggcgcc ggaccgtcgt cggcgaccag
    13861 ccggtcgccg aggccaactg ctcgaacccg gcccggccgt cggtggcgag cagggcgagg
    13921 agtctgcggt caccgtcgtc gagccgcacc ggtcctcgtc gatgcggcac cggaggcggg
    13981 cgcagtcgct cgatcgcctc cgcctccaac gacccgagtt ttccgaccag gttgtccggg
    14041 ccgccgtaga aggcgtgcag cacggagtgc gcggtcacgc cctccacgcg tggggtgcgg
    14101 gggagtttgg ccagcaacag tgcctcgctg tccgcctcgc tctcggtacg gaccacgcag
    14161 gtgatctcgg tgccgccgga gctgaggctc acccaggacg tgtcggggcg tctggccagc
    14221 gcctcggcga ccgggagcga cgcggcgggc gcacatcgca cccgcaggaa ccacaggatg
    14281 gcgcccagcg cggtggggtc gaccccgccc aggacccgta ccgccccggc cgaccgcaac
    14341 cgggcgtacc ggcgggcgac ggtgcgatcc gacacgccga gaacctcggc aagggtgctg
    14401 aacggggcac ggccgtcgat ctgcagggcg tgcacgagtc gacgatccag ctcgtcgtag
    14461 tcggattcca ccgagccgag gttagacagc gtcagatacc aacgcaaccg cctcggtttc
    14521 tggctcgggc ggctcggacg acggagcgtt gcttctgtcc cgatcgacac aaccagagga
    14581 gagcccatgg acaccgacgt gctcatcgtc ggcgccggcc cgaccggaat gacgctggcc
    14641 aacgagctgc tgatggcggg ggtgtcgacc gtgctcgtcg acaggctgtc gcagcgcagc
    14701 gacctgtcca aggcaggcgg cgtgcagtcc cgcacactgg aggcgctcga ccaacgaggg
    14761 ctgctggagc ccttgctggc caccggagac caccccgtca ccaccggcca cttcgccggt
    14821 atcccactcc cgctccactc caaccggcac cgtctgccat ggcggtccgt gccgcaggtg
    14881 gtgatcgagg gattcttcga gcggcacctc gccgcgcacg gcctccacgc ccggagggac
    14941 cacgaactgg tcggcctcgc ccaggacgac aacggggtca ccgcgacctt cgccaacggc
    15001 gccaccctcc gctcccgtca cctcgtcgcc gccgacggag cccacagcac cgtacggtcg
    15061 ctgctggggg ccgccttccc cggtcagccc ggtacgttga cgatcaccgc agccgacgtg
    15121 cggctgggcg gcgtcgatcc gtccacgtcg cacacctgga acgaggacgg gcactgggcg
    15181 gcagtgttcc cgctcggcac cgatccacag ggcaggcagc tgcgccgact ggtcctcggc
    15241 gggccgggcc ggtcactgcc gagggaggtc ccggtcaccg aggacgaaat ccgccacggc
    15301 ctgaacaccg tgttcggaac gcgggtgcac ctgcacgaac tgcgctacgc ccgccgtatc
    15361 accaacgcgt cacggcaggt cgagcggtac cggcacgggc gggtgttcct ggcgggcgat
    15421 gccgcccatg tgcaccttcc gctcggtgcg cagggcatga acaccgggat gcaggacgca
    15481 ctcaacctcg gttggaagct cggcgccgcc gtgcacggct gggcaccaga gaacctgctc
    15541 gacacgtatc acgcggaacg gcacccggcc ggggccgccg tattgcgcaa cgtccgggca
    15601 cagagcctgc tgatggactg ggccggcacg cgcgatccgg acgtgctggc cgcccgggag
    15661 gtcttcacgg ccatggccca actgccggac gtccagcacc atctcgccga cctgatgtcc
    15721 gggatggcca tccgctaccc gatgccgggc accgaaaccc atccgctcgt cggccggccc
    15781 gcaccggacc tgggcctcgg cccggcccgg gtgcacgaac tgctgcggtc cgggcgcggc
    15841 gtcctgctgg acccggccga cacgttcgcc ggggtcgccg gcccctggtc ggaccgggtg
    15901 gaccgggcgg gtcagggcgc cgacaccgag ccgatgctca tacggccgga cggctacgtg
    15961 tgctgggcag gcgcggatga cctggaaccg gcgctcgccc gctggttcgg cgagccccgc
    16021 tgagccgacg tccaggaagc cggcctctgt tgggaggtct gacgcgaacc cgccccgcct
    16081 ggacggtccg gcggcacgtc gtgatgtgct cgactgggtt tcctcggggc ggtggtcgac
    16141 cgctcaggtg tgtccggtgc cggtcgaggt cggtgcgggc catcggcgtt cgggcgcctg
    16201 gtggcgatgc gcctgggctc gacgcgggaa ctcgcctctg agcgtgggga ccgcgcagac
    16261 ctcggcggtt ctgcaggctc gccgtcagaa ggcgtacggt ccgaatcgtc cccacgccac
    16321 cacggccgcc atggccagca ggagggcgtt caccgcgacg tttcggcctt cgccgcgcct
    16381 ggcgtgcacg gcgccggcgc cgatcatgag gagtccgagt ccggtggccg cggcgggcac
    16441 caggccgacg gcggtatcga cggcggcggg caggacggtg cccagggcgc cgaggatctc
    16501 cagcaggccg atcgccttga tcgcgccggg tgagtagtcc gccgcccagg cgcccgaggt
    16561 cgcgacgacc ttctctttgg gctggagcag cttggctgca ccggcggcga ggaacaggac
    16621 ggcgaggagt ccggtgagga cccagaggag ggtgttcatg tgattccgat cgtgaagggc
    16681 acgcgggaca gcgactaaat tgaagcttca actaaaataa ccccgatcgc ttgaagcgtc
    16741 aagtgatcgg gtagggtcgt gggcatgagc aaggacgagc cgcgctggct gagcgcatcc
    16801 gagctggacg cctggaaggc gttcagcgcg atgctcatca agctgcccgc ggccctggac
    16861 gcccagcttc ggagcgacgc cggcctgaac cagttcgagt acctcgtgct ggccgccctc
    16921 tccgacgcgc cggagcgcac gctgcggatg agcgagctcg ccgtcctcgc caacggctcg
    16981 ctctcccgcc tgtcgcacgt cgtcaagcga ctggagtgac acggctacgt acgccgggag
    17041 ccctgccccg acgacggccg ctacaccaac gccctcctca ccgaggaggg ttaccggaag
    17101 ctggccgaca gcgcacccgg ccacgtccag cacgtgcggt cactcgtcct ggacccgctg
    17161 gaacccgagc agatcgaaca actacgcctg atctccctgc agatcctcca tgggatggac
    17221 cccgaccttg cctggccgga ccgccactga cccgcgatcg agcggtgccc gtcccggccg
    17281 gcgggatatt cggcatcaca cctcggcatc gccctgaccg gtcctcacac cgccgcgtcg
    17341 acgccctccg ggccctcggc acggcagacg ctccagggcg gcgggcacgg cgaacgcgca
    17401 agcacgagac gctccgagcc cggggtatca gctcgggaac aagctgagtc accacggcgc
    17461 ctggtgcccc gccgagtgca ggagggtgcc accgccgcgt ccgtggtcac gtcctggtcg
    17521 cggtcccggc ggctggtgac ggtgtgccgt cggccgcagg gggggaagtg acgtactggg
    17581 cttccccgtt gccgagcgac cagtcgatcg acgcgttctc ggtcagagtg acgaagacgt
    17641 tgcgtggtgc ggttcccgcg taggcgtggg ccaggtcggc gatccggcgg tacagcgcct
    17701 gcttctgctc ggatgtgcgt ccggagcgca gggtgatcgc gacgtacacg atgtcgtcgt
    17761 cgcggtcgat gtcgaagtaa ccgccgtagt gcagtgtgct gttggtgccg tcgtggctga
    17821 ccaggatctg gaagtggtcg tcgggcggga tgccgatcgt ctcgatgagg gcgtcgtgca
    17881 cggcgcggcc gagtgcgccg agtcggttgc tgtcggcgcg cagcgcgtcg atgcggacga
    17941 gtggcatggc ggtggcttcc tctcgggtgg tgcggacgtc cgcggatcag cggcggtgga
    18001 agtgggcggt gagcggaccg ggggcgtcgt cgccgcgctc ccacagcagc tcgcgggtgc
    18061 tctggatgag tcgttccctg gtacccatga ggagattgta catactagta gttacagaaa
    18121 tggggagggg gctgccgtcc ccgggttccc tggcgcaact cccgtgctgt gtcggcgatc
    18181 tgtaacggtc cagcctcaaa gtgcacactg gtggcgcccc ggagagcgcc tgtggtgcac
    18241 tggggaaacg tgggtttgtc tccttcacgg gggagtgatg acgccttccg ccttttctgc
    18301 ttcgtgccct cgctgcggct ggggatcggc tccgggtgcc acgttctgcg gcaagtgcgg
    18361 cggggccctg gcgaccggcg ggacccctgc ggcgccgtcg gccggcgctg caccgctccc
    18421 ggcgaacctg tccaaagggt ccaccttcgc gcccgcggcc ggcagccgct ccgccgcggc
    18481 gtcggccgcg ggatcgacct tcgcgcccgc cacgggcggt ggcaccgccg ccgtgccgtc
    18541 caacggatcc acgttcacgc gcgccacggc cggccgctcc gccaacgcgc ctcgctgggg
    18601 cggtggtcgg gacctgaccc ggtatctgtg cgccgcggcc tatctccatc gcgagtacgc
    18661 caggtcgctc atcagggaga tcgcggccga accccatctg ggggtggcga tggccccggc
    18721 gtgcgacgtg cccgtcgtgc tccggcacgc ctaccgggcc aacgcccgcc gacacagccg
    18781 ggatctgctg ctcgccgccc tgttcgtgct ggccgtcgtg ttcaccttct gggccggcag
    18841 gccgcaagcc accctgctga tgctgctctt cgcctgggtc acggtgttct ccttcgaact
    18901 ctccacgaaa tacgggcgcc acctccaggg cctccgcccg gggcgcttcg accccgccgc
    18961 cgcgccccca ccgctcaatc ccgagatcgc cgccggcctg cgtcagatcg gcgattacgc
    19021 tcaggggaac gtcacggcgt acagcggcta ttcaccgttc atcgggtacg ggaacgaact
    19081 cgaatcgtgg tccctgacgt tcgacgtcac cacgtcgagc ggggcggggg tgacggcgcg
    19141 ggacttcgac gtgaaggatc tctatgccca tatcgcccag cgcgtcggcg cgttgtccct
    19201 gccctgcctg gagatcgaag agcggctctt cgtggacggc gcgaccctcc tgggcgaccg
    19261 gcgcttcctg ccggacccgc tcgggcggcc cgtcgcctcg attccgcagg accggatgga
    19321 cgagctgaag cgggcgcccg aggagggggc ccgcccctat ctggtggtgc attccaccgg
    19381 ctggggcggc gagttggtca cgtcgctctt cctgcgtttc ttccggtcgg actccaatct
    19441 ctatgtcgag gcggttcaga cggtgttgtg cccgttgctc gaccgctacc gggtcatcga
    19501 caccctcatg ccccgcccgc cggtgcgtga tgtcctcgaa ctgctcgcgc agacgctggt
    19561 cagcaccgtg ttcgtgctgt tcgcctcgcc cgtgcgcgcg gtcgccggat tctccccgga
    19621 ctactggatg ttctggcggc tgcgccggca gtacaaactc atcacccagc tccggaactt
    19681 cgactacggg gcgcggcaga gcgtgcggca gaaggcggcg gacggcaggc accgccgcta
    19741 tttccagaag gccgactgcg gcatggtcct caagaccgtc gaaaagcggg ttctggacgc
    19801 cctcgtggaa ttcgccgagg cgaggggtat cgacgtgagt gaactggtgc agcgtcagga
    19861 aatcatcatc aacaacggca tcatcgcgac ccagggcgcg aaggtggaat ccagctcggt
    19921 cgcgaccggt gagaagtccc gggtctcgat gaacattctc aacaagatcc ccctggtgcg
    19981 actggactga caacggaagg ggacgaggaa gagcgatgcg gaggaacgac gggatcatcg
    20041 cgaccggcgg ctcgaacgtc gtcggcaacg ccgtggcgag cggccggggc gcgcgggccg
    20101 aggtgcagaa cagcgggctg tcccaaggtg acggcgggcg gcagccgtcg gcccaggaga
    20161 tcggcgacct gctgtcccgg ctgatcgacg aactcggccg gtccgatcac cccgaccgcg
    20221 gcgacctgat cgaggccgcc gaggacgcgc gcgaggaggt caccgcggag gcaccgcgca
    20281 agggcaagct gaagctgttc gccaagggcc tcgtggaggc cgtaccggga ttcacggccc
    20341 tcgcctccct ggcggtgacg atcgaagagg cgatccgcgg gctgtagaag ccacaagcca
    20401 caagccacaa gccacaagcc acacgtcaca agtcgcgggc cggggcccgg ggacgccggg
    20461 acgcacgcga agcgcaccgg aaccccagga cgctggacat caggacgccg ggggagacga
    20521 ccatgccatc ctgcttacgc tgcggtgcgg acctcggcgg caccgcagcg acccgctgcc
    20581 cgcggtgcgg aacgccctgc cgggacggca catggcacgg cacctaccag ccccgcgccg
    20641 cagccgacga cgactacgtc cgcgtcggcc ccaccatcct cccgcgctgg atgccgtggc
    20701 tgctggcggc cgtactcgtc gggggcgggg cggcgacgta cctgctgctc cactcgccct
    20761 cggacccctc gccccggacg gtcgacgcca ccccgtggac caccccgccc ccggcccccg
    20821 gcgccgcccc cgtgacaccc ggctacggcg acacccccac cgtcccgtac acccccaccg
    20881 tcccgtacac cccacccgac gccctggtac cgagcgccgc ctcgcccccc gacgacgcgg
    20941 gcgcggtggt ggagcagttc tatcgggaca tcaacgacca cgacttcgcg gcggcctgga
    21001 agctcggcgg ccggaacatc ggcggcgcct cgtaccagga ctggcaggcg ggctacgcca
    21061 cgacggcgca catcgaggtc ggcgtggtgg acaccgaggg cgccgggcag gtcaccgcgg
    21121 tgatcaacgc gacccagacg gacggctcga cgaaggtgtt ccgcggaacg tacacggtgt
    21181 ccggcggcgc gatcgtcagc gcggacatca cccagcggtg accgcccgcc gccgggcgcg
    21241 tgctcagccg aagcggagca cgggcttgat gacctgaccg gcggaggcgg cctgggcggc
    21301 gcgctcgatc tcggcgaacg ggaactcggt gatgatgtcg tggaggggaa gtgtgccctc
    21361 gcggtggagc gcgacgaggt gcgggatgaa ctcggcgggc cgggcgtcac cctcgatcac
    21421 cccgcggatc cggaggccct tggtcatcac ggtcatgatg tcgaacgtgg cctgaccgcc
    21481 gatgccgacc agtgccaggg tgccttgcct gcgcagcgcg gtgacggcct gggagatcac
    21541 ctcggcctgt ccggtggtgt cgatggcgtg atggggcccg ccgccggtga ggtcgcggac
    21601 ggcctcggcg acgtcgtcgg tggtggggtc gacggccgcg gtggcaccga attccagggc
    21661 cttggcgcgg cgggcgggaa gcgggtcgac ggcgatgacg tcacagccct cggcgaccgc
    21721 ggccatgacg gagctgaggc cgacgctccc ggtgccgaag accgccacgg acgaaccctt
    21781 cggcgggcgc agcacgttga ggaccgtgcc gacgccggtc tgcacgccgc agccgagcgg
    21841 cgcggcgatc gcgggcggca ggtcggcggg caccttgacg acgttgctgc ggtgcgcgat
    21901 tgcgtggctg gcgaacgcgg actggccgaa gaagttgccg aagacggtgt cgccgttggc
    21961 ccggctgagg ggagtcgtgc cgtcggggcg cgcgccgctg gcgttgaggg cgaagatgcc
    22021 ggtctcgcag taggcggggt ggcgggcgct gcactggccg caggtggtgc agctgcggta
    22081 gctcagggcg acactgtcgc cgggccggac ggtgtcgacc tcctcgccca cggcctcgac
    22141 gacgcccgcg ccctcgtgcc cgaagaccat cgggctgcgc tccgcgggcc agctccgccg
    22201 ggcgctgagg tcggtgtggc agatgcccgc ggccgtcatc ctgaccagga tctcgtccgg
    22261 ccgcggcgcg gcgatgacga ggtcgtcgtg gacggtgaac ggcccgccgg gggactcgac
    22321 gagggctgcc tgaatacgca tggggtcctt gggtgttggt cgccggggtc gggcgggggg
    22381 tggggggccg cggtgccgcg tcccggtcag tcgcggtcga ggaggaagta gaagtaccgg
    22441 ccgtcgtcga ggacgtcctt gccgttcatg acgcccagga gggtggtgtc gtcgaggcgc
    22501 ttgaagtggt cgatgacggg ctggccgtcg tacaccatcg aggcggtcga ctccccgcgg
    22561 aattcgacca tccacaagct ggcctcgccc ttgcccgcct cgacgtggga gaacagctcc
    22621 ccgtccgggc cgcggcagat cagcggccgt acgtcggaga gggaacggaa gtccttgcca
    22681 tgccagttgg cggctttcag caggccctcg acacggtgcc cggtgacgaa tgcgctgccc
    22741 tt
//
