LOCUS       NZ_CP047146            22718 bp    DNA     linear   CON 30-JAN-2024
DEFINITION  Streptomyces sp. GS7 chromosome, complete genome.
ACCESSION   NZ_CP047146
VERSION     NZ_CP047146.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. GS7
  ORGANISM  Streptomyces sp. GS7
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9067183)
  AUTHORS   Li,J., Ni,J. and Li,Y.
  TITLE     Multiple polyene macrolides produced by antifungal Streptomyces from
            gut of Macrotermes barneyi facilitates the termite-fungus mutualism
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9067183)
  AUTHORS   Li,J., Ni,J. and Li,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-DEC-2019) State Key Laboratory of Microbial
            Technology, Shandong Unversity, 72 Binhai Road, Qingdao, Shandong
            266237, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 20-NOV-2019
            Assembly Method                   :: SPAdes v. Nov-2019
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/30/2024 05:53:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,019
            CDSs (total)                      :: 7,925
            Genes (coding)                    :: 7,616
            CDSs (with protein)               :: 7,616
            Genes (RNA)                       :: 94
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 309
            CDSs (without protein)            :: 309
            Pseudo Genes (ambiguous residues) :: 0 of 309
            Pseudo Genes (frameshifted)       :: 107 of 309
            Pseudo Genes (incomplete)         :: 258 of 309
            Pseudo Genes (internal stop)      :: 29 of 309
            Pseudo Genes (multiple problems)  :: 79 of 309
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:40:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 156968
            Orig. end                         :: 179686
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP047146.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Jinfeng Ni.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22718
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22718
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22718
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12718](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12718
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    504..517
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.24"
                     /tool="antismash"
     misc_feature    complement(504..518)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.7"
                     /tool="antismash"
     misc_feature    complement(513..528)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.72"
                     /tool="antismash"
     misc_feature    685..694
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.55"
                     /tool="antismash"
     misc_feature    688..708
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.96"
                     /tool="antismash"
     misc_feature    691..708
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.28"
                     /tool="antismash"
     misc_feature    818..834
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.5"
                     /tool="antismash"
     misc_feature    complement(818..834)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 19.61"
                     /tool="antismash"
     misc_feature    complement(820..835)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.59"
                     /tool="antismash"
     gene            881..2164
                     /locus_tag="GR130_RS00695"
                     /old_locus_tag="GR130_00695"
     CDS             881..2164
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003981569.1"
                     /locus_tag="GR130_RS00695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_00695"
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_159502919.1"
                     /sec_met_domain="Aldedh (E-value: 1.2e-23, bitscore: 82.3,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSAPAWPTVAAEPKEDDRTEGRGEGGAEGGSARLRAAALRRVRD
                     FLAADGGVVHELLCEISTHRAARYEIESTIATLDGALDEVAAHRPGRVPRLAAFMPSNV
                     ILYSYALYLLVPALYTDELVFRPSSRVKDQMRRLHALLAERHRLPITLSGASQREFLRE
                     EVLPADVVVFTGAYRNAEQIRGQLSPGQLFLFLGSGVNPFVVAPGADVAQAARDAIAIR
                     VLNTGQDCLGPDLFTVHESLLGPFVDALVGELKGLRYGPYSDPDADFGPIFYEDALEEA
                     AQFLARNRAGIVHGGHVDFRTRRVDPTVVVGEEVSPRTHVPEFFAPIFNVAGYRDQDAL
                     AATLTTGMFTERALGSSVYGDAPELVAALRRRTTVTVDTTLLSIDNGNAPFGGYGRMAN
                     YISDGQELRAEPVLISQAVAAHRPGAAR"
     misc_feature    998..1000
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            2161..3900
                     /locus_tag="GR130_RS00700"
                     /old_locus_tag="GR130_00700"
     CDS             2161..3900
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055: pyruvate oxidase/decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003981568.1"
                     /locus_tag="GR130_RS00700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_00700"
                     /product="thiamine pyrophosphate-binding protein"
                     /protein_id="WP_159502920.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 5.9e-43, bitscore:
                     145.3, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.4e-17, bitscore:
                     62.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPRTYPSAWAAVADHLRHLGTGAVFGLPGDDMAPLGELERADTS
                     VVLCRDQRNAVFMATGYALAAGRPGVCVIGKGPALTNALTGVLEARSAAAPLLLIADGT
                     RLDRLGTGAFQELDQLTAVRPYVKWAARVDEPDRLPGTLEKAVALAVNGTPGPVYVELA
                     EQLADRPVTRTGPWRNAAPQRLAPDPDALAATARRIAAARRPLLLVGGGARHRNTGRRI
                     ERLAERLGAGVFCTASGRGAVAEDHPLYCGVSGLYTVAPADALWREADLVVALGSRLEE
                     TATFGWPDAEAGEPPVVQAVLGEDGLSMERPGAYVLGDAGRIVDGWHDLLAGHEAGTGW
                     PDRVREVRAGLARRAADRAAEAEQAAPEGTVPVARVLSSLDRAVPADRVLVQENGLQDM
                     WSYYFPHWTLGAGGGSVVPSEQTPLGFGAAAAVGVRLAGPAGRPVVALVGDGAFHLFRA
                     ELPSVADARVAVLYVVLDNGGYGWLQSNLDRVSGAGSRFAFTAARPTGTEGLAAAYGLG
                     YRRVTDADALDAALAAAWQEVAGGTASVVEVAVSLADTPPGMAGSAGDFPEREGAEEDP
                     HGG"
     gene            complement(4124..4960)
                     /locus_tag="GR130_RS00705"
                     /old_locus_tag="GR130_00705"
     CDS             complement(4124..4960)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005318404.1"
                     /locus_tag="GR130_RS00705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_00705"
                     /product="ABC transporter permease"
                     /protein_id="WP_159502921.1"
                     /transl_table=11
                     /translation="MTSYEAPPHPAPAALRRDEGRIAVRSHLRHTGALVRRNLLQIRQN
                     PESMTDALLMPVVLTLLFVFVFGGVLGAGGDRTRYLGFLVPGLMVILGMTIAMAVGTGV
                     NDDFRTGLMDRFRTLPIARSSVLIAKVVVETGRMLVAIAVLLAVAALLGFDVAGRWPGL
                     LAATGLTAVFGTSLVWTFMLLGLTLRSAQAVQGLSVVVLTPLQFGSSIFVSPATMPHWL
                     ESLTRLNPLTHMADAARGLALGEGPVAGPVTWTVLWSVGLTAVTAPIALAKFARKT"
     gene            complement(4994..5653)
                     /locus_tag="GR130_RS00710"
                     /old_locus_tag="GR130_00710"
     CDS             complement(4994..5653)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021443.4"
                     /locus_tag="GR130_RS00710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_00710"
                     /product="DUF1707 domain-containing protein"
                     /protein_id="WP_159502922.1"
                     /transl_table=11
                     /translation="MTQPQRPDLHKESAPSPTAPRQPSVLASDAEREDMIERLREATVE
                     GRLTLEELAERYEAAYLARTREELASVGEDLPAAAPPPSPATAGQRVFKAVFGDLTLSS
                     PALENGIEATAVFGDLTLDLCSSPAPSTGELTISARAVLGDVHLLLPEGVRVELNCSKL
                     FGDLRDLTRAHSGPESVTPLVRITGSAVFGDIVVAHPSSDRRTYWQKWLDERRRGA"
     misc_feature    complement(5964..5979)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.54"
                     /tool="antismash"
     misc_feature    complement(5965..5979)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.18"
                     /tool="antismash"
     misc_feature    5976..5991
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.82"
                     /tool="antismash"
     misc_feature    5987..6002
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.46"
                     /tool="antismash"
     misc_feature    6092..6107
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.44"
                     /tool="antismash"
     gene            6096..7340
                     /locus_tag="GR130_RS00715"
                     /old_locus_tag="GR130_00715"
     CDS             6096..7340
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016570969.1"
                     /locus_tag="GR130_RS00715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_00715"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_159502923.1"
                     /transl_table=11
                     /translation="MPELADTGRRIKELRVGAGMTQHDLAGSDMSSSYISLVERGKRIP
                     SGRALKILAERLGVGVTEISGGAESAESTGRVRRLDLVGRLVAARRQWEGGDAEGALRE
                     FRALAETESAGRQDDVYTEAQLAIAEILGSLGRADEGAAVLLRMLDALAAAPYAEARLR
                     ALIALADLLESAGRVQDGLRYALTGSLESDRAPGTGFHSLLVLDVLTRCAYWSGCAHWA
                     PATDRGRPPAHGVLPGPRASIELHRALDLWDRGAADRAAELLADTVRRVTPAAGFRLWE
                     KINGRYALLLLGRGERSAARSIVERGLVVASVAQEPDFPLWLMTAEAVCAEAAGDPARV
                     RSLGTELAALPDTGRSHEKAAALLEIAAAHERIGDREKAAGYFRYSAELFRRAQAYRHA
                     DRARERLTELLEKRN"
     gene            complement(7435..7614)
                     /locus_tag="GR130_RS00720"
                     /old_locus_tag="GR130_00720"
     CDS             complement(7435..7614)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018538451.1"
                     /locus_tag="GR130_RS00720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_00720"
                     /product="DUF5708 family protein"
                     /protein_id="WP_043270175.1"
                     /transl_table=11
                     /translation="MKGIAVGIFLAIVGVILWLTTKEVETPVISLHKAGLVLAIVGGAE
                     ALFALLGLGKKSNK"
     misc_feature    complement(7579..7593)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.69"
                     /tool="antismash"
     gene            8035..9303
                     /locus_tag="GR130_RS00725"
                     /old_locus_tag="GR130_00725"
     CDS             8035..9303
                     /EC_number="2.3.1.179"
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (11-420). E-value:
                     5.1e-60. Score: 195.5. Matches aSDomain:
                     nrpspksdomains_GR130_RS00725_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) t2fas"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016578549.1"
                     /locus_tag="GR130_RS00725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_00725"
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="WP_159502924.1"
                     /sec_met_domain="t2fas (E-value: 1.7e-143, bitscore: 477.1,
                     seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 8.5e-51, bitscore:
                     171.8, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELRAADRRRVVVTGCGVVSPVGNTTADFWAALLAGRSGVGAVTR
                     FDASGLPVRIAGDVKDFDPAADASLTPQEARRSDRFTQYAVAAAAQALRAAGLTPPDGI
                     DPYRFAAVIGSGYGAAPAIQQQYDVLKEQGPRRVSPYHSVLTAIDHPASLLSIKYGIAG
                     PSNAVSAACATGAVAIGEAAELIRHGRADIALAGGTDDSLTAVDLAGTANARALSRRND
                     DPEGASRPFDRDRDGFVMAVGATVVTLEEAGHAERRGAPILAEVAGYAATTDAHHATAP
                     DPTGAGAVRAMRAALADAGKDPEDVGQISAHGTGTVLNDRIEAAALREVLGPDTLRRTP
                     VTAVKSMTGHMLGASGAAEAAAAVLSLRDRVIPPIRNCDHPGEPDLDLVTKGARDWDGD
                     VVLSNSFGFGGHNAVLVLARYTG"
     misc_feature    8041..8043
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        8068..9294
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GR130_RS00725_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="5.10E-60"
                     /label="GR130_RS00725_PKS_KS.1"
                     /locus_tag="GR130_RS00725"
                     /protein_end="420"
                     /protein_start="11"
                     /score="195.5"
                     /tool="antismash"
                     /translation="VVTGCGVVSPVGNTTADFWAALLAGRSGVGAVTRFDASGLPVRIA
                     GDVKDFDPAADASLTPQEARRSDRFTQYAVAAAAQALRAAGLTPPDGIDPYRFAAVIGS
                     GYGAAPAIQQQYDVLKEQGPRRVSPYHSVLTAIDHPASLLSIKYGIAGPSNAVSAACAT
                     GAVAIGEAAELIRHGRADIALAGGTDDSLTAVDLAGTANARALSRRNDDPEGASRPFDR
                     DRDGFVMAVGATVVTLEEAGHAERRGAPILAEVAGYAATTDAHHATAPDPTGAGAVRAM
                     RAALADAGKDPEDVGQISAHGTGTVLNDRIEAAALREVLGPDTLRRTPVTAVKSMTGHM
                     LGASGAAEAAAAVLSLRDRVIPPIRNCDHPGEPDLDLVTKGARDWDGDVVLSNSFGFGG
                     HNAVLVLARY"
     gene            9318..10004
                     /locus_tag="GR130_RS00730"
                     /old_locus_tag="GR130_00730"
     CDS             9318..10004
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024698.4"
                     /locus_tag="GR130_RS00730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_00730"
                     /product="GNAT family protein"
                     /protein_id="WP_159502925.1"
                     /transl_table=11
                     /translation="MQGRLVTLEWPGDDDWAAIASWLRPGSPAAVMSGDWELLGAADVE
                     QANRSGRVSHMVIRTHDGERIGTVSYQRTGRIGGYSVGGAIGTPELWRRGYGAEAVVLL
                     VDYLFHQLDAHRVQVTTAAYNKSIIRLMTKTQFVVEGILRDHCYLDGAYHDAIVWGILR
                     DEHYASLKPSATNRVLAVGLEDFVTEDDKVQAREILAGHLAETGRSAVAAFLDTAASAG
                     NERGAA"
     gene            10001..12718
                     /gene="lanKC"
                     /locus_tag="GR130_RS00735"
                     /old_locus_tag="GR130_00735"
     CDS             10001..12718
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038151.1"
                     /locus_tag="GR130_RS00735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_00735"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_159502926.1"
                     /sec_met_domain="micKC (E-value: 1.9e-224, bitscore: 746.2,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1e-08, bitscore: 33.2,
                     seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDGAESFALADRTFFDWPGNWDLEATRFPAPPLPEGWTYDENEA
                     WSFCRPPRDENRQLPDQGWKIHVSAAPEDAERTLADVAAYCVRHGLLFKYLKSANVLRA
                     LSRKYAQRSSAGKLLTVYPVDEADLARTLEGLDAVVGGRPGPYVLTDLRFREGPLYVRY
                     GGFRTRYMEDAEGGGDLVTAVRRPDGTLEADRRTPVFRTPDWVPLPDVLKDSLAARQAV
                     DDFPYRITGALHFSHGGGVYRAEPAGEHALGAGARSVVLKEGRPYSGTDGVGRDAVARL
                     AHEHRILTTLAGLPGIPRTFGTFEVRDHLFLVLEDVEGKDFQSWLAGVYPLTVPEPDEA
                     AVAAHRDRALALFARIEALVASVHGRGIRIGDLHPGNFIIQPGDIPVLLDFEVADAIDR
                     ATPSSLGAPGFHRADATGADGDRYALAAIALWLFLPLAALGGLSPDKAPALLDIAARRF
                     GLPEDLVARLAGQLAPAAQAGPSEGAPPCALVSAPGPFPAPDLIASIGRGLRDSATPHR
                     TDRLHPGDFAQFAEGGAGFAHGAAGVLWARHTVLGERDAHHVAWLRAAADRVPAERIGF
                     YDGLHGIAYVLAELGDEEGARRALDRAGGQLDVRHCPSLYRGLSGAGLNLLHFADRWAD
                     DTARATALRLADRVTDRLADALREPVEYQRRTGSRHAGGLMYGWSGPALFLLRAHQATG
                     DTGLLDQAVWAVHRDLDRCASGPQDTLQVDEGFRLLPYLDNGSAGIALVAAELLGHRDD
                     ARIRAALPGLLRACSADFVIESGLWGGRAGLIGTLAALREWVPLPAADAERQLHRHLAN
                     LQQHAMRLNGATVFPCDGRARISMDVATGGAGVLLALAAAERGTRLLPFLTDSRSAAAV
                     HPAVPERARGAHGAATPAVPSGPEGTADNGREVS"
     misc_feature    complement(13058..13073)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.7"
                     /tool="antismash"
     gene            13292..15082
                     /locus_tag="GR130_RS00740"
                     /old_locus_tag="GR130_00740"
     CDS             13292..15082
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024846.4"
                     /locus_tag="GR130_RS00740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_00740"
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="WP_159502927.1"
                     /transl_table=11
                     /translation="MGKDPHHGGKTGAPLSLCVIGCGPRGASIVERILANVPALYGDRP
                     LDLHVVDPYPPGAGRTWRTDQPGLLWMNSAADQVTMYPDESVACAGPPRPGPTTAGWLD
                     APLHDGAYAARRDQGRYLRSFFAEVTGARPASVRLHVHRARAVDLLRTAPYGRPGRQRV
                     VLDSGRTVLADRVVLAQGHVDTLAAPAPPGLTRIGPGPADPDALDRIPAGAPVVVRGLG
                     LVFVDCLALLTEGRGGRFSGAPGGSLRYLPSGREPRLYAGSRRGVPLPPKPSATAPAAP
                     DGGLRFATPGACRAALARPGASFGRDVWPLVLAELAWHHYRALFAAAPDRTCMTWQDFD
                     AQYALLFTDAGRLAKLARAAVPDPADRLDLDRLADPLAGRRFTGGDDLQRQLRAHLAAT
                     LRRRTGPAAGPELALVDGLRRTGEVVEELWRSGDLDEASVADALRRFALGTYLSSGPPP
                     LRARQLLALAEAGVVTFVGPGMRVETGPAGFRALSPAVPGAVHEAAVLLDARLAPAGPD
                     RVADPLLRALAARGELAPDPAGEDGGPPRLSGAELHPVAADGTVHRDRIVAGPAQFPRP
                     RANAVAFRQNDAIARRLLAR"
     gene            complement(15105..15809)
                     /locus_tag="GR130_RS00745"
                     /old_locus_tag="GR130_00745"
     CDS             complement(15105..15809)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018092317.1"
                     /locus_tag="GR130_RS00745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_00745"
                     /product="response regulator transcription factor"
                     /protein_id="WP_236572628.1"
                     /transl_table=11
                     /translation="MAERAQAPEESRPDIRVLVADDQAAVRSGLVLVLQTDPGITVVGE
                     AGDGEAAVRMAGELRPDVVLMDVQMPLLNGVAATRRIVERGLAEVLVLTTFDLNEYIFG
                     ALRAGAGGFILKNAEPAVLVGAVREVAHGEGFLTPAIARRLISEFALQAPSSRPSLPDG
                     AAQTLDTLTKRELEVLACIGRGLANSAIAQTLNLAEGTVKTHTSRILSKLNLRSRVQAA
                     ILAQQHGVTLRG"
     gene            complement(16033..17232)
                     /locus_tag="GR130_RS00750"
                     /old_locus_tag="GR130_00750"
     CDS             complement(16033..17232)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="GR130_RS00750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_00750"
                     /product="sensor histidine kinase"
                     /protein_id="WP_159502928.1"
                     /transl_table=11
                     /translation="MGFFAGCLILYVLGGPRVMGGEIPVWQAVLPVLVLCAATAFRSVL
                     PLAAVLVGTVTVSLEAAASGGLGPVLIYTDLLYAAALYGAPWLCRALQFGTVAATMAAT
                     VVFLFIGDRSEGVTTGLIVALLLISPVWTGVLIRNHKEQADAERQRAAQINRLAELDRK
                     TVLQTERTRMARELHDLVANHLSAIAIHSSAVLSLQEAHGGRKDRGGGADEEDPVLRAL
                     AVIRENSVQGLAEMRRMVVLLRSDRAVDDDWDRPQLNALGALVEQARPAAAAAELTLHT
                     EFPESFPEVSSVIEVTAYRIVQEALTNCLKHAAAGRVRIRCETGAEQLTISVESPLARP
                     DVPARQRRPGDPATAGAGAGLAGMSERATLVGGVFDAGPDRSAPGRWRVRAVLPLGQNS
                     "
     gene            17561..18277
                     /locus_tag="GR130_RS00755"
                     /old_locus_tag="GR130_00755"
     CDS             17561..18277
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GR130_RS00755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GR130_00755"
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="WP_159502929.1"
                     /transl_table=11
                     /translation="METNAALLDLDQELLDQELPGQFGPDQVPVFVVPVGDVPEGNDPH
                     PGCGSELTADSCPSLNGHTRATLDAASRGWLLARLPARVRAAMTAAGHWELYGTRGLLV
                     VACGDGARQMGFSVESVRRVRQETSALHTPYEILTARESRAAAGRPAAERERLITRFWV
                     RKDAALQAVGRGLSLAPERIEAGFPADSGTVAVPGPCGSEIPVSVRNFTFSPAYEFAVA
                     TPEPHCVTPAFAYSVR"
     misc_feature    17563..17574
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: strong, score: 21.4"
                     /tool="antismash"
     gene            18534..18938
                     /locus_tag="GR130_RS41505"
                     /old_locus_tag="GR130_00760"
     CDS             18534..18938
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018447.4"
                     /locus_tag="GR130_RS41505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_00760"
                     /product="transglycosylase family protein"
                     /protein_id="WP_159502930.1"
                     /transl_table=11
                     /translation="MPSPLAVRTAVALPSALLALLTAAGGAAADEPPPSGTDWEKVAAC
                     ESSGDWHSNTGNGYHGGLQISPSTWRAYGGDRFARRADLASRAEQIAVAERIVQDQGLG
                     AWPNCAPQALARARYVADRGYPGRRLGLRL"
     gene            19054..19464
                     /locus_tag="GR130_RS00765"
                     /old_locus_tag="GR130_00765"
     CDS             19054..19464
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GR130_RS00765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GR130_00765"
                     /product="hypothetical protein"
                     /protein_id="WP_236572631.1"
                     /transl_table=11
                     /translation="MRSPDSKTAGFTNGFTNREGQDRTVKRTARINILLAGVLGLLLVG
                     GAASPAMAWGDGENDAEGYSYTSFHAGFRCEGRTSRVCINGPVGSGNVRDAQNISITGN
                     PGSTASPVSNSGSNNSGSSVTGPSAGSSNKSG"
     misc_feature    complement(19085..19102)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.46"
                     /tool="antismash"
     gene            complement(19564..20013)
                     /locus_tag="GR130_RS00770"
                     /old_locus_tag="GR130_00770"
     CDS             complement(19564..20013)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016570975.1"
                     /locus_tag="GR130_RS00770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_00770"
                     /product="hypothetical protein"
                     /protein_id="WP_236572632.1"
                     /transl_table=11
                     /translation="MKRLVQAGTVAGVCGLVLFGSGAAQAQTPPNGSLLSAVTGTDGSL
                     LSAVTGADLATVTGMMSGVLCDNRLVDFNYQSPRVKSPHPCVNGPVHSGNNKNSNNFRN
                     RGNPVDAGNPKIAAGSTNSLNESHGNERASHNDISKIAKLVKVIR"
     gene            <20266..>20370
                     /locus_tag="GR130_RS39610"
                     /pseudo=""
     CDS             20266..>20370
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007827324.1"
                     /locus_tag="GR130_RS39610"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="alpha/beta hydrolase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGPSDILVIQNRRDPCTPYFGALRMRAALGGRARL"
     gene            complement(20424..20849)
                     /locus_tag="GR130_RS39615"
     CDS             complement(20424..20849)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006138650.1"
                     /locus_tag="GR130_RS39615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cupin domain-containing protein"
                     /protein_id="WP_201304768.1"
                     /transl_table=11
                     /translation="MSDQARDQATEPLVLSAALASFDALWSPRIVTRVNDYDVRVAKVR
                     GEHLWHAHTDTDEFFLVVEGELFISLREAAGERTVRLPRGSVFTVPRGTEHKPHSPSGA
                     SILVFEPTGTMTVGDRHEEIPDHVDATAGHALGAAGR"
     gene            20901..21905
                     /locus_tag="GR130_RS00780"
                     /old_locus_tag="GR130_00780"
     CDS             20901..21905
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010468233.1"
                     /locus_tag="GR130_RS00780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR130_00780"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_159502932.1"
                     /transl_table=11
                     /translation="MPQGSSQPAAGRPHRVVVIVDENSNPFELGCAIEVFGLPRPEIGR
                     DLYDFRLCSPEPRTLMRDGFFTLTGVADLAAADEADTLIVPNRPDVDVPRRAAVLDAVR
                     RARDRGARLVGFCSGAFTLAEAGVLDGRRATAHWRWADSFRARFPAVRLETDVLFVDDG
                     DILTAAGSAAALDLGLYVVRRDHGAEIANAVSRRLVFAGHRDGGQRQFVERPVPRVADS
                     SLAPLLAWAQEHLDAPLTVSGLAARATVSPATLHRRFRAQLGTTPLAWLTGERLALACR
                     LIERGEPRLDVVARKCGLGTAANLRALMRRETGLTPSAYRRRFGPPTAPRPAA"
ORIGIN
        1 agcagctggg ccagctcgat ggcgacccgg gcgtgcagga cgggcgcgga gcgggtgagc
       61 gggtcgtcca acagccggcg cagcgccgcc tcgtggcggg cgggatcgtc gagccggccg
      121 aggaccgtgg ccagctccca gcgcgcctcc cagcggacct cgtcctggtc ggcgccgtcg
      181 gcctgctcca ccacggactc cagctggcgc agcgccgcgg accagtcgcc ggccagctgg
      241 ctggcccggg cggcgaccaa ctggcccacc aggccgaggc gttgggcgag ccggtcggcg
      301 ggctgctcgg tggcgctcag cgcctcgacg gtggtgccca ggcgctgcgc gatggaccgc
      361 gcgatcttgg tgccggggat cctgcggccg ttctcgacca atgagacgta gctgggggag
      421 aggtcgtcgc cggcgagatc cccctgggac agaccctgag cgcgccggac ctcccgcact
      481 cgcttcccga aggcaggctg ctcaatcgtc aagaaaatcg ctcgcagttg agttgggggg
      541 acggacggtg acggtcggtg gacggcgtta cgcggtgtgg tgacggtgag tctactcacc
      601 gggccgtggc gcggtgcggc ctgtggacgg cccggcgtgg gccggacggg cgtccggccg
      661 tggcatccgg ggccaccagt gagtcatttt ttgtcatgga gatgttaggg cggtgctctc
      721 cctggtcggc gcgcaggtgc tgggaagggg tggttgtggt gggggttccg ctgcgcgacc
      781 tgttgtcatg ttctctcgtt gccggcaatg actctgcttg acaataaatg acaattggct
      841 gacgctgacc ctccatggac tacgccccga ggagggacac atgagctccg ctcccgcatg
      901 gccgaccgtg gccgccgagc cgaaggagga cgaccgcacc gaaggccgtg gtgagggcgg
      961 tgccgaaggc ggcagcgcgc gcctgcgggc ggcggcgtta cgccgggtcc gggacttcct
     1021 ggcggcggac ggcggcgtcg tgcacgagct gctgtgcgag atctccaccc accgcgccgc
     1081 gcgctacgag atcgagtcga ccatcgccac cctcgacggg gccctggacg aggtggccgc
     1141 ccaccggccc ggccgggtgc cgcggctcgc cgcgttcatg ccgtcgaacg tcatcctcta
     1201 ctcctacgcc ctctacctcc tcgtccccgc gctctacacc gacgagctgg tcttccgccc
     1261 ctccagccgg gtcaaggacc agatgcggcg gctgcacgcg ctgctcgccg agcggcaccg
     1321 gctgccgatc accctcagcg gcgccagcca gcgggagttc ctgcgggagg aggtgctgcc
     1381 cgccgacgtc gtggtgttca ccggcgccta ccgcaacgcc gagcagatcc gcggccagct
     1441 ctcccccggg cagctcttcc tcttcctcgg atcgggcgtc aacccgttcg tcgtcgcccc
     1501 cggggccgat gtcgcgcagg ccgcccggga cgcgatcgcc atccgggtgc tgaacaccgg
     1561 tcaggactgc ctgggccccg atctgttcac ggtccacgag tcgctgctcg gcccgttcgt
     1621 ggacgccctc gtcggcgagc tgaaggggct gcgctacggc ccgtactccg acccggacgc
     1681 cgacttcggg ccgatcttct acgaggacgc gttggaggag gcggcccagt tcctcgcccg
     1741 caaccgggcc ggcatcgtgc acggcgggca tgtcgacttc cgcacccggc gggtagaccc
     1801 cacggtcgtc gtcggcgagg aggtgagccc gcgcacgcac gtaccggagt tcttcgcgcc
     1861 gatcttcaac gtggccggct accgcgacca ggacgccctg gccgcgaccc tgaccaccgg
     1921 catgttcacc gaacgcgccc tgggctccag cgtctacggc gacgcccccg aactggtcgc
     1981 ggcgctgcgc cggcggacca ccgtcaccgt cgacaccacg ctgctgtcca tcgacaacgg
     2041 caacgcgccc ttcggcggct acggccggat ggccaactac atctccgacg gccaggagct
     2101 gcgcgccgag ccggtgctga tctcgcaggc cgtcgccgcg caccgcccgg gagccgcccg
     2161 gtgaccccgc ggacctaccc cagcgcctgg gcggccgtcg ccgaccacct gcgccacctg
     2221 ggcaccggcg cggtgttcgg gctccccggg gacgacatgg cgccgctcgg tgaactggag
     2281 cgtgccgaca cctccgtcgt cctctgccgg gaccagcgca acgccgtctt catggcgacc
     2341 ggttacgcgc tcgccgccgg ccgccccggg gtgtgcgtga tcggcaaggg cccggcgctg
     2401 accaatgcgc tcaccggcgt cctggaggcg cgctcggccg ccgccccgct gctcctgatc
     2461 gccgacggca cccggctcga ccggctcggc accggcgcgt tccaggagct ggaccagctc
     2521 accgcggtcc gcccgtacgt caagtgggcg gcccgcgtcg acgagcccga ccggctgccc
     2581 ggcaccctgg agaaggccgt cgcgctcgcc gtcaacggca cccccggccc ggtctacgtc
     2641 gaactcgccg aacagctggc ggaccggccg gtgacccgta ccgggccctg gcgcaacgcc
     2701 gcgccgcaac ggttggcgcc cgaccccgac gcgctggccg ccaccgcgcg ccggatcgcc
     2761 gcggcccggc gcccgctgct gctggtcggc ggcggcgccc ggcaccgcaa caccggccgc
     2821 cggatcgagc ggctggccga gcggctgggc gcgggcgtct tctgcaccgc ctcgggccgc
     2881 ggcgcggtcg ccgaggacca tcccctgtac tgcggcgtca gcggcctgta cacggtcgct
     2941 cccgcggacg cgctgtggcg cgaggcggat ctggtcgtcg cgctgggcag ccggctggag
     3001 gagaccgcga cgttcggctg gccggacgcg gaggcgggtg aaccacccgt cgtccaggcc
     3061 gtattgggcg aggacgggct gtccatggag cggcccgggg cgtacgtcct cggggacgcc
     3121 gggcggatcg tcgacggctg gcacgacctg ctcgccggcc acgaggcggg caccgggtgg
     3181 ccggaccggg tccgggaggt acgggccgga ctggcccggc gggccgcgga ccgcgccgcc
     3241 gaggcggagc aggcggcgcc cgagggcacc gtgccggtgg cgcgggtgct gtcctccctg
     3301 gaccgcgcgg tccccgcgga ccgggtgctc gtccaggaga acggcctcca ggacatgtgg
     3361 tcctactact tcccccactg gacgctcggt gcgggcggcg ggtcggtggt gcccagcgag
     3421 cagacaccgc tgggcttcgg cgccgccgcc gctgtcggcg tccggcttgc cgggcccgcc
     3481 gggcgccccg tggtggcgct ggtcggcgac ggcgcgttcc acctcttccg ggccgagctg
     3541 ccgtccgtcg ccgacgcacg ggtcgccgtc ctctacgtcg tgctcgacaa cgggggctac
     3601 ggctggctcc agtccaacct ggaccgggtc tccggcgcgg gctcgcggtt cgccttcacc
     3661 gcggcgcgcc ccacgggcac cgagggcctg gctgccgcgt acgggctggg ctaccggcgg
     3721 gtgaccgacg ccgacgcgct ggacgcggcg ctggccgccg cctggcagga ggtcgccggc
     3781 ggtaccgcct cggtggtgga ggtggcggtc tcgctggccg acaccccgcc ggggatggcc
     3841 ggttcggcgg gcgacttccc ggagcgggag ggcgccgagg aggatccgca cggcgggtga
     3901 gcgcggcggc gggcgccgcc gggagcgtgc gcccgccgcg accgccgtgc tgtggcccgg
     3961 cggtgtacgt cgtccacgtc gtacaccgcc gggccttgtg cgtgccccgc ccctgccggc
     4021 cacgggggaa gccggacggg ggcggggcac gtcttcttcg tacggagggg gccgcgccgc
     4081 ggcgtgccgg gggtggttgc cgccgctccg tacgggtccg gggtcaggtc ttcctggcga
     4141 acttcgcgag ggcgatcggg gcggtgaccg ccgtcaggcc caccgaccac agcaccgtcc
     4201 aggtcaccgg gccggccacc gggccctcgc ccagggccag tccgcgggcc gcgtcggcca
     4261 tgtgggtcag ggggttgagg cgggtgaggc tttcgagcca gtgcggcatc gtcgccggcg
     4321 acacgaagat cgaggacccg aactgaagcg gcgtcaggac caccaccgac agcccctgca
     4381 cggcctgggc gctgcgcagc gtcagcccca ggagcatgaa ggtccacacc agggacgtgc
     4441 cgaacacggc ggtcagcccg gtcgcggcca gcaggccggg ccagcgccct gcgacgtcga
     4501 agccgagcag cgcggcgacg gccagcagga ccgcgatggc gaccagcatc cggccggtct
     4561 ccaccacgac cttggcgatc agcaccgagg agcgcgcgat gggcagggtg cggaaacggt
     4621 ccatcaggcc cgtgcggaag tcgtcgttga cgcccgtgcc gaccgccatc gcgatggtca
     4681 tccccaggat caccatcagg cccggcacca ggaaccccag gtaccgggtg cggtcgccgc
     4741 cggcgccgag cacgccgccg aagacgaaga cgaacagcag cgtcagcacg accggcatca
     4801 gcagcgcgtc ggtcatcgac tccgggttct gccggatctg caggaggttg cggcggacca
     4861 gcgcgccggt gtgccgcaga tgggaccgca ccgcgatccg cccctcgtcg cgacggagcg
     4921 cggcgggcgc ggggtgcggc ggggcctcgt acgacgtcat cgctgctcct ccctcgatcc
     4981 ggcggccggt ggctcaggcc ccgcgccggc gctcgtcgag ccacttctgc cagtacgtgc
     5041 gccggtcgct gctgggatgg gcgacgacga tgtcgccgaa gaccgcggag ccggtgatgc
     5101 gcaccagcgg ggtgacggac tccgggccgg agtgcgcccg ggtcagatcg cgcaaatcgc
     5161 cgaagagctt gctgcagttc agctcgaccc ggacgccctc ggggaggagc aggtgcacat
     5221 cgccgagcac cgcgcgggcc gagatggtca gttcgccggt cgacggggcc ggggaggagc
     5281 acaggtcgag ggtcagatcg ccgaagacgg cggtggcctc gatgccgttc tccagggcgg
     5341 ggctgctcag tgtcagatcg ccgaacaccg ccttgaacac ccgctgtccg gcggtagccg
     5401 gcgagggcgg cggtgcggcg gcgggcagat cctcgccgac cgacgccaac tcctcacgcg
     5461 tacgggccag ataggccgcc tcgtagcgct cggccagttc ctccagcgtc agccggcctt
     5521 ccacggtggc ttcccgcagc cgctcgatca tgtcctcgcg ctcggcgtcc gaggcgagca
     5581 ccgagggctg ccggggcgcg gtcggcgacg gcgccgactc cttgtgcaga tcggggcgtt
     5641 ggggctgcgt catgggaggg gcctccgctg gtcgggcggt agtgatgcgg gcgccgcgat
     5701 gcccccgcgc ggtctcatcc gaccacgtca cagggggtgc ggacatcggc gtgcggtact
     5761 acatcgaaag gtgcaggcgg cggttgcggg cacccggttc ggcctatccc tcgtccggtt
     5821 ccggcggacg ggcgggcgtt gcgtcaggtc cgcgcgccgc tccccgccgc tccccgtatt
     5881 ggttgtgcgc accattgatc cggggcctgc gaaatgatct cgtcatggct tggtgaagtc
     5941 ctgtgtgaag tcgagtgaag aaagtaaaaa ggatgtcgac ttcttcttga ctgcttggta
     6001 aagtagcctg cgctcattgt gactcgggat ttgtctagcc gaccacagtc gccgaccaca
     6061 gtcatcaaac cgttcgaatc cggaggattt gtcgaatgcc tgagctggcg gacaccggga
     6121 ggcgaatcaa agagctccgg gtcggcgcgg gaatgaccca gcacgatctc gccggatccg
     6181 acatgtcctc cagctacatc tcccttgtcg aacgcgggaa gcgcattccc agcggccggg
     6241 ccctcaagat cctggccgaa cgcctcgggg tcggcgtgac ggaaatatcc ggcggcgccg
     6301 agtcggccga atccaccggc cgggtccgca ggctggatct ggtcggtcga ttggtcgcgg
     6361 cccgccgcca atgggagggc ggcgatgccg agggtgcgct ccgggaattc cgcgcgctgg
     6421 ccgagaccga atcggccggc cggcaggacg acgtatatac cgaggcgcag ctcgccattg
     6481 ccgaaatact ggggtcactg ggccgcgccg acgaaggcgc ggccgtcctg ctgcggatgc
     6541 tggacgcgct cgccgccgcg ccgtacgccg aggcccggct gcgcgcgctg atcgcgctcg
     6601 ccgacctgct ggagtcggcc ggccgggtcc aggacgggct ccgctacgcg ctgaccggct
     6661 cgctggagtc cgaccgggcc cccggcaccg gcttccactc gctgctggtc ctcgacgtcc
     6721 tgacccgctg cgcctactgg agcggctgcg cccactgggc gccggccacc gaccgcggcc
     6781 ggccgcccgc gcacggggtg ctgcccgggc cgcgcgccag tatcgagctg caccgggcgc
     6841 tggacctgtg ggaccgcggc gcggcggacc gggcggcgga gctgctggcc gacaccgtgc
     6901 gccgggtcac cccggccgcc ggattccggc tctgggagaa gatcaacggc cgttacgcgc
     6961 tgctgctgct cggccgcggc gagcggagcg ccgcgcgcag catcgtggag cgcgggctgg
     7021 tggtcgcctc cgtggcgcag gaaccggact tcccgctctg gctgatgacc gccgaggcgg
     7081 tctgcgcgga ggccgccggc gatccggcgc gggtccggtc gctgggtact gagctggccg
     7141 cgctgcccga caccggccgc agccacgaga aagccgccgc gctcctggag atcgcggcgg
     7201 cacacgagcg gatcggggac cgggaaaagg cggccggtta cttccggtat tccgccgagc
     7261 tgttccggcg cgcccaggcg taccggcacg ccgaccgggc ccgggaacgg ctcaccgaac
     7321 tcctcgaaaa gcggaactga cgcccgccgg ggagacgtgc ggtccacccg ggcgggcgtc
     7381 ggagcgggaa ctgccaaaag cgttggccgt gccacaaatg ccgtaaatgc gacgctattt
     7441 attcgacttc ttccccagcc ccaggagcgc gaagagcgcc tccgcgccgc cgacgatggc
     7501 caggacgagt ccggccttgt gaagtgagat gaccggcgtc tccacttcct ttgtggtgag
     7561 ccacaggatg acgccgacga tcgccagaaa aatgcctacg gcaataccct tcatgagttc
     7621 cctcgtccct cgttggtggt gccggagctg gttgaccgct ccagcgtccc gcccggcccg
     7681 ccggtccgga tcatccgcag gtaggcactt tccccggcgc ctcctgtcac tttctatgta
     7741 cgccggaccc ctacccgcgg cccggcgcac gggagcggac acggggcgcg acggtggcgg
     7801 cagccggcgc accgcgcttg tctggcgccc catcagtcaa atttcatgac tctgctagtc
     7861 atgcggaggg tggcgttttc gctggtgagc gacgttcttg cccctgttga cctgctcggt
     7921 ctgctgactc tgctgcgagc gaggcgttga caatcctctg actcggctgt catctttctg
     7981 gtcatgaggg caccccagtc gtgacaaggg gcagaaaagt aggaggcggg tttcatggag
     8041 ttacgggcag cggatcggcg gcgggtcgtc gtcaccggct gcggcgtggt gtcccccgtg
     8101 ggcaacacca ccgcggactt ctgggccgcc ctcctggccg gccgcagcgg cgtcggcgcc
     8161 gtgacccgct tcgacgcctc cggcctgccg gtgcgtatcg cgggtgacgt caaggacttc
     8221 gacccggccg ccgacgcttc cctcacgccc caagaggccc gccgcagcga ccggttcacc
     8281 cagtacgcgg tggccgccgc cgcccaggcg ctgcgcgccg ccggcctcac acccccggac
     8341 ggcatcgacc cgtaccgctt cgccgcggtg atcggctccg gctacggtgc cgcccccgcg
     8401 atccagcagc agtacgacgt cctcaaggag cagggcccgc gccgggtctc cccgtaccac
     8461 tcggtgctca ccgcgatcga ccacccggcg agcctgctgt ccatcaagta cggcatcgcc
     8521 ggccccagca acgcggtctc cgcggcctgc gccaccggcg cggtggccat cggggaggcg
     8581 gccgagctga tccggcacgg ccgcgccgac atcgcgctgg ccggcggcac ggacgactcg
     8641 ctcaccgccg tcgacctggc cggcaccgcc aacgccaggg ccctctcccg ccgcaacgac
     8701 gaccccgaag gcgccagccg gcccttcgac cgggaccggg acggcttcgt gatggcggtc
     8761 ggcgccaccg tggtgacgct ggaggaggcc gggcacgccg agcggcgcgg cgccccgatc
     8821 ctcgccgagg tggccggcta cgccgcgacc accgacgccc accacgccac cgcccccgac
     8881 cccaccggcg ccggagccgt ccgcgcgatg cgggccgcgc tcgccgacgc cggcaaggac
     8941 cccgaggacg tcgggcagat cagcgcccac ggcaccggca ccgtcctcaa cgaccgcatc
     9001 gaggccgccg cgctgcgcga ggtgctgggc cccgacaccc tgcggcgcac cccggtcacc
     9061 gccgtcaaga gcatgaccgg gcacatgctc ggcgcctccg gggcggccga ggccgccgcc
     9121 gcggtgctct cgctgcggga ccgggtgatc cccccgatcc gcaactgcga ccaccccggg
     9181 gaaccggatc tcgacctggt caccaagggc gcccgcgact gggacggaga cgtggtgctc
     9241 agcaattcgt tcggcttcgg cggacacaac gccgtacttg tactggcccg ctacaccggc
     9301 tgaggaggga acgcaccgtg cagggacgac tggtgacctt ggaatggccc ggcgacgacg
     9361 actgggcggc gatcgcctcc tggctgcggc ccggctcgcc ggcggccgtg atgagcggcg
     9421 actgggaact gctgggcgcc gccgacgtcg aacaggccaa ccgctccggg cgggtcagcc
     9481 acatggtgat ccgcacccac gacggcgaac gcatcggcac cgtcagctac cagcgcaccg
     9541 gccggatcgg cggctactcc gtcggcggcg ccatcggcac cccggaactc tggcgccgcg
     9601 gctacggcgc ggaggccgtg gtcctcctcg tcgactatct cttccaccag ctcgacgcgc
     9661 accgcgtcca ggtcaccacc gccgcctaca acaagagcat catccggctg atgaccaaga
     9721 cccagttcgt ggtcgagggc atcctgcggg accactgcta cctcgacggc gcctaccacg
     9781 acgcgatcgt gtgggggatc ctccgcgacg agcactacgc ctcgctcaag cccagcgcga
     9841 cgaaccgcgt actggccgtc gggctggagg acttcgtgac cgaggacgac aaggtccagg
     9901 cccgcgagat cctcgccggg cacctggcgg aaaccggccg cagcgcggtc gcggccttcc
     9961 tcgacacggc cgcgtccgcc gggaacgagc ggggtgccgc atgagggacg gcgccgagag
    10021 cttcgccctg gccgaccgca ccttcttcga ctggcccggc aactgggacc tggaggccac
    10081 ccgcttcccg gctccgccgc tccccgaagg ctggacgtac gacgagaacg aagcctggtc
    10141 cttctgccgc ccgccccggg acgagaaccg ccaactcccc gaccagggct ggaagatcca
    10201 cgtcagcgcg gcccctgagg acgccgagcg caccctcgcc gacgtcgccg cctactgcgt
    10261 ccggcacggc ctgctcttca agtacctcaa gagcgccaac gtcctgcgcg cgctgagccg
    10321 caagtacgcc cagcgctcct ccgccggcaa gctgctgacc gtctaccccg tggacgaggc
    10381 ggacctggcc cgcaccctcg aagggctgga cgccgtcgtc ggcggccgtc ccggaccgta
    10441 cgtcctgacc gacctgcgct ttcgcgaggg cccgctgtac gtccgctacg gcggcttccg
    10501 cacccggtac atggaagacg ccgagggcgg cggcgatctc gtcacggccg tgcggcgccc
    10561 cgacggcacc ctggaggcgg accgccgcac ccccgtcttc cgcacccccg actgggtccc
    10621 gctcccggac gtcctcaagg actcgctggc cgcccgccag gccgtggacg acttccccta
    10681 ccggatcacc ggagcgctgc acttctcgca cggcggcggc gtctaccgcg ccgagccggc
    10741 cggggagcac gccctcgggg cgggagcgcg cagcgtcgtc ctcaaggagg gccgtccgta
    10801 ctccggtacg gacggcgtcg gccgggacgc ggtcgcccgg ctcgcccacg agcaccggat
    10861 cctgaccacg ctcgccgggc tgcccggcat cccccgcacc ttcggcacct tcgaggtccg
    10921 cgaccacctg ttcctggtcc tggaggacgt cgaggggaag gacttccagt cctggctggc
    10981 cggcgtctac ccgctgaccg tgcccgagcc cgacgaggcg gccgtggccg cccaccggga
    11041 ccgcgcgctg gccctgttcg cccggatcga ggcgctggtc gcctcggtcc acggacgcgg
    11101 catccggatc ggcgacctgc acccgggcaa cttcatcatc cagcccggcg acatcccggt
    11161 cctcctggac ttcgaggtgg ccgacgcgat cgaccgggca acccccagca gcctcggcgc
    11221 accgggcttc caccgggccg acgccaccgg tgcggacggc gaccgctacg cactcgccgc
    11281 catcgccctg tggctgttcc tgccgctcgc cgcgctcggc ggcctgtccc ccgacaaggc
    11341 gcccgcgctg ctcgacatcg cggcccgccg gttcggcctc ccggaggacc tggtggcccg
    11401 gctggccggg cagctcgccc cggcagctca ggcagggccg tccgaaggcg ccccgccgtg
    11461 cgccctggtc agcgcccccg gcccgttccc ggccccggac ctgatcgcct ccatcgggcg
    11521 cgggctgcgc gacagcgcca ccccgcaccg cacggaccgg ctgcaccccg gggacttcgc
    11581 ccaattcgcc gagggcggcg cggggttcgc gcacggcgcc gccggcgtcc tgtgggcccg
    11641 gcacaccgtg ctcggggaac gcgacgcgca ccacgtcgcc tggctgcggg ccgccgccga
    11701 ccgggtaccg gccgagcgga tcggcttcta cgacgggctg cacggcatcg cgtacgtcct
    11761 cgcggagctg ggcgacgagg aaggggcgcg ccgcgcgctg gaccgggccg gcgggcaact
    11821 cgacgtacgg cactgcccca gcctctaccg cggactgtcc ggcgccggcc tcaacctgct
    11881 gcacttcgcg gaccgttggg cggacgacac ggcacgcgcg acggccctgc gactggccga
    11941 ccgggtcacc gaccggctgg ccgacgccct ccgggagccg gtcgagtacc agcggcggac
    12001 cggttcccgg cacgccggcg ggctgatgta cggctggtcc ggaccggcgc tgttcctgct
    12061 ccgcgcccat caggccaccg gcgacaccgg cctgctggac caggcggtct gggccgtcca
    12121 ccgcgacctc gaccgctgtg cgtcaggacc gcaggacacg ctccaggtcg acgaggggtt
    12181 ccggctcctg ccctatctgg acaacggcag cgcgggcatc gccctggtgg cggccgaact
    12241 cctcggccac cgcgacgacg cccggatccg tgcggccctg cccgggctgc tgcgggcctg
    12301 ctccgccgac ttcgtcatcg aatcggggct gtggggcgga cgcgccggac tgatcggcac
    12361 cctcgccgcc ctgcgcgagt gggtcccgct gcccgcggcg gacgccgagc ggcagctcca
    12421 ccgccatctg gccaatctcc agcagcacgc catgaggctg aacggcgcga cggtcttccc
    12481 ctgtgacggc cgggcccgga tctccatgga cgtggccacc ggcggggccg gcgtactgct
    12541 ggccctcgcc gccgccgaac ggggcacccg gctgctcccg ttcctcaccg actcgcggtc
    12601 cgccgcggcc gttcacccgg ccgtcccgga gcgcgcccgc ggcgcccacg gcgccgcgac
    12661 ccccgccgtc ccgtccgggc cggagggcac tgcggacaac ggaagggagg tgtcgtaaat
    12721 gaccatcatg gacctgcagg gcatcgaggt gcccgccgag cgtgaggctc aggcgctggg
    12781 ctcgaccatc agcaccggct gctgacgcgc cgtcaggtgc cccgcatcgg cacctgatac
    12841 ggctcgtcac caccgtggtc aaccaccact gcgacacatc gaagggaggt ttccgatatg
    12901 tcgatcatgg acctgcaggg catcgaggtg cccgccgagc gtgaggccca ggcgctgggc
    12961 tccaccgtca gcaccggttg ctgacgccgt ccggtgcctg cacagcaccg gacctctcac
    13021 cgtacacatc accaccgaat cgcggaaggg aggtgtcgta aatgaccatc atggaccttc
    13081 agggcatcga ggtgccggcc gagcgtgagg cccaggctct cggctccacc gtcagcacgg
    13141 gctgctgaca cggcgcccgg tggtcccgcg ctgcggtgcg ggccaccggg ctcctgcggt
    13201 ttccgggcgg ttcccggcgc gcgctccgga tcgggtccgg gaggcgcgtt cacgagaggc
    13261 agggcaggac gggaggacgg ggaggacggc gatggggaag gacccgcacc acggcgggaa
    13321 gaccggcgca ccgctctccc tctgcgtcat cggctgcggc ccgcgcggcg cctccatcgt
    13381 ggagcgcatc ctcgccaacg tgcccgccct gtacggcgac cgcccgctgg acctgcacgt
    13441 cgtcgacccg tacccgccgg gcgccggccg cacctggcgc accgaccagc cgggcctgct
    13501 gtggatgaac tccgccgccg accaggtcac catgtacccc gacgagagcg tcgcctgcgc
    13561 cggaccaccg cgccccggcc ccaccaccgc cgggtggctc gacgccccgc tgcacgacgg
    13621 cgcctatgcc gcccgccgcg accagggccg ctatctgcgc agcttcttcg ccgaggtgac
    13681 cggcgcgcgg cccgcgtcgg tacggctgca cgtccaccgg gcgcgcgccg tcgacctgtt
    13741 gcgcaccgcc ccgtacggcc gcccgggacg ccagcgggtg gtcctcgact ccggccggac
    13801 cgtcctcgcc gaccgggtgg tcctcgccca gggccatgtg gacaccctcg ccgcccccgc
    13861 cccgcccgga ctgacccgga tcggccccgg ccccgccgac ccggacgcgc tggaccgcat
    13921 accggccggg gcgcccgtcg tcgtccgcgg cctcggcctg gtcttcgtcg actgcctggc
    13981 cctgctgacg gagggccgcg gcggccgctt ctccggggcg cccggcggct cgctgcgcta
    14041 tctgccgtcc ggccgcgaac cccgcctgta cgcgggctcc cgccgcggtg taccgctgcc
    14101 cccgaagccg tcggccaccg cgcccgcggc gcccgacggc ggcctccgct tcgccacgcc
    14161 cggcgcctgc cgcgccgcgc tggcccgccc cggcgcgtcc ttcggccgcg acgtctggcc
    14221 gctggtgctg gccgaactgg cctggcacca ctaccgcgcc ctgttcgccg ccgcgcccga
    14281 tcgcacctgc atgacctggc aggacttcga cgcccagtac gccctgctgt tcaccgacgc
    14341 cggccggctg gccaaactgg cccgcgcggc ggtccccgac cccgccgacc gcctcgacct
    14401 cgaccggctg gccgacccgc tggccggccg ccgcttcacc ggcggcgacg acctccagcg
    14461 gcagctgcgc gcccacctgg ccgcgaccct gcgccgccgt acgggaccgg cggccggccc
    14521 cgaactcgcc ctggtggacg gcctccgccg gaccggcgag gtcgtcgagg agctgtggcg
    14581 ctccggcgac ctggacgagg cctcggtcgc cgacgcgctg cgccgcttcg ccctcggtac
    14641 gtacctcagc tcgggcccgc cgccgctgcg cgcccggcag ctgctggcgc tggcggaggc
    14701 gggcgtggtg acgttcgtgg gccccggcat gcgcgtggag accgggccgg ccggcttccg
    14761 ggcgctcagc cccgccgtcc ccggcgccgt ccacgaggcg gccgtcctcc tggacgcccg
    14821 gctggcgccc gccggtccgg accgggtcgc cgacccgctg ctgcgcgcgc ttgcggcccg
    14881 cggtgagctg gcaccggacc ccgccggaga ggacggcggg ccgccgcggc tgtccggtgc
    14941 ggagctgcac ccggtcgccg cggacggcac cgtgcaccgc gaccggatcg tggccggccc
    15001 ggcccagttc ccgcgcccgc gggccaacgc cgtggccttc cgccagaacg acgccatcgc
    15061 ccggcggttg ctggcccgct gagtccggcc ccggcgcccg gccctcaccc ccgcagggtg
    15121 accccgtgct gctgcgccag gatcgccgcc tgcacccggc tgcgcaggtt cagcttcgac
    15181 aggatccggc tggtatgcgt cttgacggtg ccctcggcca ggttcagggt ctgggcgatg
    15241 gcgctgttgg ccagcccccg cccgatgcag gccagcacct ccaactcccg cttggtgagg
    15301 gtgtccaggg tctgcgcggc cccgtccggc agcgagggcc gcgacgacgg cgcctggagg
    15361 gcgaactcgg agatcagccg ccgggcgatc gccggggtca ggaagccctc cccgtgcgcc
    15421 acctcccgta cggcgccgac caggacggcc ggttccgcgt tcttgaggat gaagccgccg
    15481 gccccggccc gcagcgcccc gaagatgtac tcgttgaggt cgaaggtggt cagcaccagg
    15541 acctccgcga gaccgcgctc gacgatcctg cgggtggcgg cgacaccgtt gagcagcggc
    15601 atctgcacat ccatcagcac gacgtcgggc ctcagttcgc cggccatccg caccgccgcc
    15661 tcaccgtcgc cggcctcgcc gacgaccgtg atgcccgggt cggtctggag gacgaggacc
    15721 agaccggaac gcaccgccgc ctggtcgtcg gcgaccagca cccgaatgtc cggccggctc
    15781 tcctcagggg cctgggcacg ctccgccacc ggtttctcca ccgcatactc cacttctgat
    15841 caccgtccag gaactcggga ctcggacacc cggcgctcgg acacccggga ctcggacgca
    15901 gagcgctcgg acacacagga ctgcgggacg cgctcccgca ggacgcgccc cccaaggacg
    15961 cggaccccgg tcggcgcggc cgggcagcgg cacccgccgg cacccgcacg tcggccaaca
    16021 cccgcccgcc catcaggagt tctgacccaa cgggagcacc gcgcggaccc gccagcggcc
    16081 gggggccgac cggtcggggc ccgcgtcgaa gacgccgccg accagcgtgg cccgctcgga
    16141 catcccggcg agcccggcgc cggccccggc ggtcgccgga tccccggggc gccgctgccg
    16201 ggcgggcacg tccgggcggg ccagcgggct ctcgacggag atggtcagct gctcggcgcc
    16261 ggtctcgcag cggatccgca cccgcccggc cgcggcgtgc ttgaggcagt tggtcagcgc
    16321 ctcctgcacg atgcggtacg cggtcacctc gatcaccgac gacacctcgg ggaagctctc
    16381 ggggaactcg gtgtgcagcg tcagctccgc cgcggcggcg gcgggccggg cctgttcgac
    16441 cagcgccccc agcgcgttca gctgcggccg gtcccagtcg tcgtccaccg cccggtcgga
    16501 gcgcagcagc accaccatgc gccgcatctc ggccagcccc tgcacgctgt tctcgcggat
    16561 caccgccagc gcccgcagca ccggatcctc ctcgtccgcc ccgccgcccc ggtccttccg
    16621 gccgccgtgg gcctcctgga gggacagcac cgcgctggag tggatggcga tggcgctgag
    16681 gtggttggcg accaggtcgt gcaactcccg tgccatccgg gtgcgttcgg tctggagcac
    16741 ggtcttgcgg tccagctccg ccagccggtt gatctgcgcc gcccgctgcc gctcggcgtc
    16801 cgcctgctcc ttgtggttcc gtatcaacac cccggtccag accggggaga tgagcagcag
    16861 cgccacgatc agcccggtcg tcacgccctc ggaccggtcg ccgatgaaga ggaagacgac
    16921 ggtggcggcc atggtcgccg cgacggtgcc gaactggagc gcccggcaca gccagggcgc
    16981 cccgtacagc gccgccgcgt acagcaggtc ggtgtagatc agcaccggcc ccagcccgcc
    17041 gctggccgcc gcttcgaggc tgacggtcac ggtgcccacg agcaccgcgg ccaacggcag
    17101 cacactgcgg aaggcggtcg ccgcgcacag caccagcacc gggaggacgg cctgccatac
    17161 ggggatctcg cctcccatca cccgcggccc gcccaggaca tacagaatca ggcagccggc
    17221 gaagaaaccc accgccattc tgaggtcacg gagcggtatg ggcgcgcggc gcagttgctt
    17281 acttgcgaaa tggcgtaacc acacaccagg acactacttc cgcgtacggc ccgatccctt
    17341 ggcctggccg ccgaattggg tcgctgctcc ctacatcgaa gtatgtagcc ggacatcagc
    17401 aggagggatg actcgaaggc tccggagggc atgcaaacct agggctgact gtaccgatcg
    17461 atgtaggcga aataggggga gcacgagtcg cccgccgatt gaaggctgcc actcaccggt
    17521 gcggccgagc caccgctcaa ctgtggagga cggaaagtac gtggaaacga acgccgctct
    17581 tctcgatctt gaccaggaac tcctcgacca ggaactccct ggccagttcg gccccgatca
    17641 agtccccgtc ttcgtggtcc ccgtggggga cgtccccgaa gggaacgacc cgcaccccgg
    17701 gtgcgggagc gagttgaccg ccgacagctg tccgtccctc aacggacaca ccagagccac
    17761 cctggacgcc gcgtcccgcg gctggctgct cgcccggctc cccgcccggg tccgcgccgc
    17821 gatgaccgcc gccggccact gggagctgta cggcacccgc ggcctgctgg tcgtggcctg
    17881 cggcgacggt gcccgccaga tgggcttctc cgtcgaatcc gtgcgccgcg tacgccagga
    17941 gacctccgcg ctgcacaccc cgtacgagat cctcaccgcg cgggagtccc gcgcagccgc
    18001 cggccgcccg gccgccgaac gcgaacgcct catcacccgc ttctgggtgc gcaaggacgc
    18061 cgccctccag gctgtcggcc gcggcctctc cctcgccccc gagcgcatcg aagccggttt
    18121 ccccgccgac tccggcacgg tcgccgtccc cggcccctgc ggcagcgaaa tcccggtcag
    18181 cgtccgcaac ttcaccttct ccccggcgta cgagttcgcg gtggcgactc cggaaccgca
    18241 ctgtgtcacg cccgcgttcg cctattccgt caggtaaatt cccgcggaca ccgcccgttt
    18301 ccaccccggc ggtccgggga aagggaaacg ggccgatccg cggggcggct tccgtctccg
    18361 cggctgaatt gccgtatccc gaccgacagg aggcccaccc gggtgaaaac gcctccgtcc
    18421 ggcctacgtg atcctgccga aaagcatatt gacgggttac ctggtgcctg cccctcagtc
    18481 gcggcgggca ggaccccacg acgccgccgg agcacgcagg aggaagtacc gccatgccgt
    18541 cgcctctcgc cgtacgcacc gccgtcgcac tcccgtccgc cctgctcgcc ctgctgaccg
    18601 ccgccggcgg cgccgcggcg gacgaaccgc ccccctccgg taccgactgg gagaaggtcg
    18661 ccgcctgcga gagcagcggc gactggcact ccaacaccgg caacggctac cacggcggcc
    18721 tccagatctc cccgtccacc tggcgcgcct acggcggcga ccggttcgcg cggcgcgccg
    18781 acctggccag ccgcgccgag cagatcgccg tcgccgagcg catcgtccag gaccagggcc
    18841 tgggcgcctg gcccaactgc gccccgcagg ccctcgcccg cgcccgctac gtggccgacc
    18901 gcggctatcc gggacggcgc ctcgggctgc gtctctgacc gggcggaacg cgtcccggcc
    18961 cgccggccgg tccggccgga gggccgtcac ggtgaaatcg gtggtcggac agggtgaacg
    19021 cgcgagaccg gccgctgtac aggcttggcc ggcatgaggt cgcccgatag caagactgcg
    19081 gggtttacca acgggtttac caaccgcgag gggcaggacc gcacagtgaa gagaacggca
    19141 cgcatcaaca ttctgctcgc aggggttctc ggcctcctgc tggtcggcgg cgcggcgtca
    19201 cccgccatgg cctgggggga cggagagaac gacgccgagg gctacagcta caccagcttc
    19261 cacgccggat tcaggtgcga gggccgcacc agcagggtct gcatcaacgg ccccgtgggc
    19321 agcggaaacg tcagggacgc gcagaacatc agcatcaccg gcaatcccgg cagcaccgcc
    19381 agcccggtgt ccaacagcgg ttccaacaac agcggttcca gcgttacggg cccctcggcg
    19441 ggcagcagca acaaatcggg ctgaccggtc agccgggccc cagggcctgc ccgaaccggc
    19501 cccggagcga tccggggccg gttttccgtt gtccgcgggc cggagcccgg tgggggaacg
    19561 gcctcagcga atgaccttga cgagcttggc gatcttggag atgtcgttgt gactggcccg
    19621 ctcgttaccg tgggactcgt tgaggctgtt ggtggagccg gcggcgatct tggggttgcc
    19681 ggcgtccacc gggttcccgc ggttgcggaa gttgttgctg ttcttgttgt tgccgctgtg
    19741 caccggcccg ttgacgcacg gatgcggcga tttcaccctg ggggactggt agttgaagtc
    19801 gacgaggcgg ttgtcgcaca gcacgccgga catcattccg gtcaccgtgg cgagatcggc
    19861 gcccgtcacc gcggacagca gtgatccgtc cgtacccgtc accgcggaca gcagcgatcc
    19921 gttcggaggg gtctgcgcct gcgcggctcc ggagccgaac agcaccagac cgcacacccc
    19981 ggcgaccgtt cccgcctgca ctagtctttt cacgacgctc cttgcttcgt cagcctgccg
    20041 tccggacgta tcgtgctgcc gttgtccgcc cgtgtcgtcg ataacccgca gggagccaaa
    20101 ccctcacggg ccataatcag tcgggtggcc caacagcccc gtacggcgcg gcccggcccg
    20161 gaaggtgcgg ggggcagccc gacccgaagt ccgcgcggcc ctcatgggta gcggcggcgg
    20221 cgccaacccc ccttgatcca ttgcgactta cgcggggatc cctccgacgg gccgtccgac
    20281 atcctggtga tccagaaccg tcgggacccg tgcaccccgt acttcggtgc gttgcggatg
    20341 cgggccgccc tcggcggccg ggcgcggctg ggcgcggccg ggccggagca cccgtgcggg
    20401 ggcggtccgg cccggccgta ctctcagcgg cccgccgccc cgagcgcgtg cccggcggtc
    20461 gcgtccacgt ggtccgggat ctcctcgtgc cggtcgccga ccgtcatcgt gccggtgggc
    20521 tcgaagacca ggatcgaggc gccggacggg gagtgcggct tgtgctcggt gccgcggggg
    20581 acggtgaaga ccgagccccg ggggagtcgg accgtccgct cccctgcggc ttcgcgcagc
    20641 gagatgaaca gctcgccctc cacgaccagg aagaactcgt ccgtgtcggt gtgggcgtgc
    20701 cagaggtgct cgccccgcac cttggcgacc cgtacgtcgt agtcgttgac ccgggtgacg
    20761 atccgggggc tccacagggc gtcgaaggag gccagcgccg cgctgaggac gagcggctcg
    20821 gttgcctggt cacgtgcttg atcactcatg gcccgatcct gtcccgggcg cgcggccgcc
    20881 gcgagtgcta ggaatcgcat atgccgcaag gatcctcgca accggccgcc ggccgcccgc
    20941 accgcgtcgt cgtcatcgtc gacgagaact ccaacccctt cgaactcggc tgcgccatcg
    21001 aggtgttcgg cctgccccgc cccgaaatcg gccgggacct ctacgacttc cggctctgct
    21061 cacccgagcc gaggacattg atgcgcgacg ggttcttcac cctcaccggc gtcgccgacc
    21121 tggccgcggc cgacgaagcg gacaccctga tcgtcccgaa ccggccggac gtcgacgtgc
    21181 cgcgccgcgc cgccgtgctc gatgccgtcc gccgggcgcg ggaccgcggc gcgcgcctgg
    21241 tcggcttctg cagcggcgcg ttcaccctcg ccgaggcggg ggtcctggac ggccgccggg
    21301 ccaccgccca ctggcggtgg gcggacagct tccgggcccg cttccccgcc gtccggctgg
    21361 agaccgacgt gctgttcgtg gacgacggcg acatcctcac cgccgcgggc agcgccgcgg
    21421 cgctcgacct ggggctgtac gtggtccgcc gcgaccacgg cgcggagatc gccaacgcgg
    21481 tcagccggcg gctggtcttc gccggccacc gggacggcgg ccagcgccag ttcgtggagc
    21541 gccccgtgcc gcgcgtggcc gactcctcgc tggcccccct cctggcctgg gcgcaggaac
    21601 acctggacgc cccgctcacc gtctccgggc tggccgcacg cgccaccgtc agcccggcca
    21661 ccctccaccg ccgcttccgt gcccagctgg gcaccacccc gctggcctgg ctgaccggcg
    21721 aacggctcgc cctcgcctgc cggttgatcg aacgcggcga gccccgcctc gacgtcgtcg
    21781 cccggaagtg cggcctgggc acggccgcca atctgcgcgc cctgatgcgt cgcgagacgg
    21841 ggctgacacc gtccgcgtac cggcgccgct tcggtccgcc cacggcgccc cggcccgccg
    21901 catgacaacc cccgccaccc gccttaacct gggaaaatgg ccggtgatct ggtcacagtc
    21961 agtctctgcg gcgatgtgat gctcggccgc ggcgtcgacc agatcctgcc gcatcccggc
    22021 gatcccgagc tgcgcgagcc gtacgtggcg gacgcccgct cctacatcgg gctggccgag
    22081 gcggcgaacg gcccgatccc ccgcccggtc gccttcccct ggccgtgggg cgacgcgctg
    22141 gcggccctcg acggggccgc gcccgccgcc cgcgtgatca acctggagac cagcgtcacc
    22201 cggagcgaca ccttcgcccc cggccggcag atccactacc gcatgaaccc cgccaacctc
    22261 ccgtgcctgg ccgcggcccg cccggacgtc tgcgtgctgg ccaacaacca cgtgctggac
    22321 ttcggccgcg ccgggctggc ggagaccctg gagagcctgg cgggcgcggg cctgcgcgcc
    22381 gcgggcgcgg gggcgaacgc ggcggcggcg cggcacccgg ccgccgtccc cctcgacggc
    22441 ggccgccggc tgctgaccct ctccttcggg atgccgtcca gcggcatccc ccacacctgg
    22501 gccgcgaccg cgcggcacgg cggggtgcac ttcgtggccc gcccgacgct cgccgccgcg
    22561 accgagctgg tggcccggct gggcccggag aagcgccccg gcgacctggc ggtggcctcg
    22621 gtccactggg gctccaactg gggctacgag gtctcccccg agcagatcgc cttcgcccac
    22681 acgctcgtcg acggcggtgt ggacgtcgtc cacggcca
//
