LOCUS       NZ_CP047147            26266 bp    DNA     linear   CON 30-JAN-2024
DEFINITION  Streptomyces sp. GF20 chromosome, complete genome.
ACCESSION   NZ_CP047147
VERSION     NZ_CP047147.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. GF20
  ORGANISM  Streptomyces sp. GF20
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7311137)
  AUTHORS   Li,J., Ni,J. and Li,Y.
  TITLE     Multiple polyene macrolides produced by antifungal Streptomyces from
            gut of Macrotermes barneyi facilitates the termite-fungus mutualism
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7311137)
  AUTHORS   Li,J., Ni,J. and Li,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-DEC-2019) State Key Laboratory of Microbial
            Technology, Shandong Unversity, 72 Binhai Road, Qingdao, Shandong
            266237, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 29-NOV-2019
            Assembly Method                   :: SPAdes v. Nov-2019
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/30/2024 05:38:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,372
            CDSs (total)                      :: 6,281
            Genes (coding)                    :: 6,197
            CDSs (with protein)               :: 6,197
            Genes (RNA)                       :: 91
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 50 of 84
            Pseudo Genes (internal stop)      :: 9 of 84
            Pseudo Genes (multiple problems)  :: 17 of 84
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:01:42
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7245716
            Orig. end                         :: 7271982
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP047147.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Jinfeng Ni.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26266
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="25"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..26266
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26266
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16266](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16266)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(104..122)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.07"
                     /tool="antismash"
     gene            239..640
                     /locus_tag="GR131_RS31370"
                     /old_locus_tag="GR131_31370"
     CDS             239..640
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008406809.1"
                     /locus_tag="GR131_RS31370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_31370"
                     /product="hypothetical protein"
                     /protein_id="WP_159313809.1"
                     /transl_table=11
                     /translation="MRVARPLSLFAALSIALAGAAATATAAPAPVPEAAAAGSGYAAPT
                     MLHCKLNVRSATKSSATVLRTLRNRNGNCPGKGGHDSVPCWLNKCGGITAGGSYTCQSG
                     GKSYKSWLPVKHQGKRAWVAIKCGTYVTP"
     gene            817..2106
                     /locus_tag="GR131_RS31375"
                     /old_locus_tag="GR131_31375"
     CDS             817..2106
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008406810.1"
                     /locus_tag="GR131_RS31375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_31375"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_159313810.1"
                     /transl_table=11
                     /translation="MRSPLSRRGFLAAGSGLAAATAFPALAGCSSLASADSDPGTLVVH
                     TQLGTTAPGSPTYRALVKEFHAEHPGLRIKNLVNGDDLPQVYETSRLARKEPDVVMVNL
                     YDKTLAWTELGATLDVKGYLDDWGLRERVLPAALKEWTDDEGRLRAFPYFAANWPVAFN
                     TSLLARAGTGSVPTTGDQLLGAARKLRAKGIAPVTVGGNDWTGQKLLAQIIQTFLTPEE
                     ARKVYASGDFGGRRVREGIDYFVELRDAGVFADKAQGLTSDTMTTQYNTEAAAIQSAMS
                     SALAKVPERTAAHSEVGGWPLAPGAAHAKPTIMRSYTLIGFWISPNGAKKISAVEKFLR
                     FMYRPESVSRFITESGRDMALRTDTVSKDFPLVAAAQRLGDQVGQVLLPDLYVPPTATQ
                     PLITATSTAFTRGTSAATVRSALESAYRTG"
     gene            2139..3074
                     /locus_tag="GR131_RS31380"
                     /old_locus_tag="GR131_31380"
     CDS             2139..3074
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015577249.1"
                     /locus_tag="GR131_RS31380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_31380"
                     /product="sugar ABC transporter permease"
                     /protein_id="WP_018894638.1"
                     /transl_table=11
                     /translation="MTLLSSAPPGAPATRSAPQAPGRTPRRKQGGVILAVPALAWYLLF
                     MVGPLVAIFVIAALHWPGMLQPVSFAGLGNVRTVLADPVFTDALVNTGIQLAVALPVMI
                     VGAYMLGYYVAQRPPGHRFLRYLLFIPGLISTPAKAMVFYAVLSPDGLFNGALDKAGLG
                     SLTDAWLASPSTALACLIVLDVWSGIGFTAVLFAARLGSVPDEVGEAAQLDGAGHWRAM
                     WRIHFPMIRDFVGVVTMLQFLWTLFGSAQNVLLLTQGGPGSSSTTLSFLVYQKAFIAAD
                     LGYSQTVGVFLFLAGLAGLLTIRRVFRQNY"
     gene            3089..3916
                     /locus_tag="GR131_RS31385"
                     /old_locus_tag="GR131_31385"
     CDS             3089..3916
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049222.1"
                     /locus_tag="GR131_RS31385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_31385"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_008406812.1"
                     /transl_table=11
                     /translation="MKFGRSWLPAHLLAWLYAALLLVPLYYLLVSAFKTNDQIFGSPFA
                     LPTSLSPHNFTEAFTSADLGAAVVNSVLVTALALALTLGLAIPAAFALARSDGRLGAFV
                     ERVFSLGFLVPTFAALFPTFLLAASTGLFHTRAFMVLFLPATAMPLSVVILVQFMRTIP
                     REMEEAARMDGASTFAVLRHVYTPMCMPGIATILLLNFLTFWNEYLYSLVIIGPDPGLR
                     TVQVALPTLKSLTGTDYGILTAGTVLTLVPVWAVYTVLQKRMQQALVSGAVKM"
     gene            3913..4989
                     /locus_tag="GR131_RS31390"
                     /old_locus_tag="GR131_31390"
     CDS             3913..4989
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010640020.1"
                     /locus_tag="GR131_RS31390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_31390"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_159313811.1"
                     /transl_table=11
                     /translation="MKERLEGRPGRSAPGNGTRPTIKAVAAAAGVSTATVSQAVNDTGR
                     ISEATRRRVLAAAAELGWSPSAPATALRRARTRTIALVVRRPTDVLGADPHFSELITGL
                     EGQLAPRGYGLLLHLVPDMAEESALYERLAAEGRIDGAVLTDARADDPRPGLLKGLGLP
                     AVLLGTPDPAAPVPGVGLGQQDAGVREAVTHLLNHGHRRIAYVAGPADLVHSGLRRAAF
                     ESALAEAGLRPVAVRHTDFTEEAAVTVTAELLARPDRPTALVFPNDSMAVCGMGAAQRA
                     GLRVPEDVSVVGYDNLPLGRWLHPRLTTVDQQVQRVGAAAALTLLAGCGEEVPAPLLDG
                     RPRLVVRESTGPAPTGRP"
     gene            5079..7013
                     /locus_tag="GR131_RS31395"
                     /old_locus_tag="GR131_31395"
     CDS             5079..7013
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0071704 - organic substance metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010062505.1"
                     /locus_tag="GR131_RS31395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_31395"
                     /product="cellulase family glycosylhydrolase"
                     /protein_id="WP_159313812.1"
                     /transl_table=11
                     /translation="MRRHSAQLTHDHAVLPWLGANFWSRTGGPLMWRDYDPKTVREELA
                     VLREHGLTMTRSFFYWPDFHPEPSRIDEELCDRFRDFLDAHTEAGMGTVPTFIVGHMSG
                     ENWDPVWRGGRDLYEDVWLVGRQAWFVSQMTRRFKDHPAVTGWLITNEMPGYGRIYQEN
                     PPSGDVVTAWAQFMCDAVRAAGGTQPVSLGDGAWGIEVTGRDNGFSLRDTAEYVDFVGP
                     HVYRSDTDRPRQHYRAAFECELAAVTGQPVVLEEFGLSTDTVSAANAGIFYRQTLHNSL
                     LGGATGWIAWNNTDYDALWDRSPYDHHPFEMHFGITDSEGRPKEPLRELAGFAEVLERV
                     DFARCRRTDADAALVVPAFLERGYPYSRPADRPLIFTSLHQGYVAARGADLPVALAREA
                     DGLAEDAALYLLPSTRQLTTRTRRALERRAREGATVYLSFCSGEHPGTRGPWFDDLDGL
                     FGVELQLSYGVAEPIEDDVLEMTFTEEFGTIKAGETLTFPVAGNEDSRAYLPVVPDGAR
                     VVATDAHGRPALLRHDTGQGRTVLATYPLEHMAARTARVNPEQTHRLYAALAEIAGVVR
                     PVTVDSPYVAADTIVHEDGRRFVWLVSQSGKELTVRPSADGTLHSLDDGDPVRDVTLPP
                     YGVRVLEQR"
     gene            7065..9401
                     /locus_tag="GR131_RS31400"
                     /old_locus_tag="GR131_31400"
     CDS             7065..9401
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018468585.1"
                     /locus_tag="GR131_RS31400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_31400"
                     /product="glycoside hydrolase family 3 N-terminal
                     domain-containing protein"
                     /protein_id="WP_159313813.1"
                     /transl_table=11
                     /translation="MADPLYRDPTAPVTARVRDLLARMTLTEKVGQVNQRMYGWHAYER
                     TPSGYRLTEAFRTEVAAFDGMGALYGLQRADPWSGVTAETGIGAADGAHVSDTVQRHVI
                     DNTRLGIPVLMVEEMPHGHQALDGTLLPVNLAVGATWNPELYEEAVAAAAAELRARGGH
                     VALVSALDLVRDPRWGRAEECFGEDPYLAARFTEALVRGAQGAPAERIAPDRAAVVLKH
                     FAGQGATIGGRNSAATELGIRELHEIHLEAALAGVRAGAAGVMAAYNEFDGLPCAASRD
                     LLTGILREEWGFDGVVMADGLALDRLVRLAGNPVTAAATALSAGCDLSLWDDCFPRLAE
                     AVDRGLVEESALDTAVGRVLALKFRLGLFEQPYTGERPRVAAPRELSRRLAQESVTLLA
                     HDGVTLPLPGRARVAVLGPNADSVPQQLGDYTAPQRPGVGLSLLAGLRAAAPAGTEITY
                     ARGCDLVGADRSALPEAVALAADSDVAILVLGGSSARAAETHFDANGAAQVTGDPDGMT
                     CGEGVDLADLALPEGQSALLDTITAIGVLVVVVLVQGRPHPLPDLTGRAAAVLSAWYPG
                     PWGGQAVADVLLGTAEPTGRLPVSVPRTAAQLPVFYNAKDHGYRGYVDQPATARHPFGH
                     GLSYTTVEYGAPRLTRPAATLAEFDEAGETGGTPPLVCSVEVRNTGDRPVRETVQLYVR
                     RVLGGTSWPRVRELRGFRHTQLAPGETSEVSFTVDARTLASVSRSGKREVEAGEYAIET
                     GPSSARTQPARLTVHDERGTTFPGP"
     gene            complement(9477..9869)
                     /locus_tag="GR131_RS31405"
                     /old_locus_tag="GR131_31405"
     CDS             complement(9477..9869)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GR131_RS31405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GR131_31405"
                     /product="hypothetical protein"
                     /protein_id="WP_201305806.1"
                     /transl_table=11
                     /translation="MPVRSSSSPTPSSCTHTASSTTPWSGPGYGSHWTGKRKRVNRQGA
                     FTHWGTVIRELLEQAEAQGELLPHIHVAQTADILVGPFAGVQAMSQVLSDYQDILTRVT
                     ALLHHILPSTVLPPILATTEITPARG"
     misc_feature    complement(9987..10003)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 22.98"
                     /tool="antismash"
     gene            complement(10001..10291)
                     /locus_tag="GR131_RS31410"
                     /old_locus_tag="GR131_31410"
     CDS             complement(10001..10291)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033537.1"
                     /locus_tag="GR131_RS31410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_31410"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_328707471.1"
                     /sec_met_domain="PF13471 (E-value: 7.5e-10, bitscore: 37.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDFETPPSPPPSIRPAWYRGRIACMEISLATVLALALCGRRVHW
                     VLGARQLPTEAHAWVWTENGAFGLSGRDRPDPRRPWAGALAAPPVPKGRRI"
     misc_feature    10328..10343
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 24.24"
                     /tool="antismash"
     misc_feature    complement(10329..10342)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.65"
                     /tool="antismash"
     gene            10336..10590
                     /locus_tag="GR131_RS31415"
                     /old_locus_tag="GR131_31415"
     CDS             10336..10590
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010639989.1"
                     /locus_tag="GR131_RS31415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_31415"
                     /product="DUF6233 domain-containing protein"
                     /protein_id="WP_159313815.1"
                     /transl_table=11
                     /translation="MSDLPADLPCLHVLRTWHAMWLARIDKAIATAEQREAETRRGAEV
                     RPPLAGARVRPLDTEQARQALVDVQACSMCRPDTDLGLL"
     gene            complement(10819..11661)
                     /locus_tag="GR131_RS31420"
                     /old_locus_tag="GR131_31420"
     CDS             complement(10819..11661)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008406748.1"
                     /locus_tag="GR131_RS31420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_31420"
                     /product="ABC transporter permease"
                     /protein_id="WP_159313816.1"
                     /transl_table=11
                     /translation="MTATHDVATTAPVSRTHGTGSKLSWAFADSWTMTRRELAHWARQP
                     VQVVVGLVFPVMMLLMFGFLIGGGKGVEGDFRSYLVPGMLTMTMAFGLEATMLSVTQDL
                     GKGVIDRFRSMPMNSGSILVGRSIADMLQSVVGLAVMIGVGAAIGWRWNNGFASFMGAV
                     GLLLLLRFAMLWIGLHLAMVAGKPEMVQAVQILVWPMAFLSNAIATPASMPAWLGGVVE
                     WNPMSATATAVRDLFGNQSAAGDSWAATHAELLAVAWPLLLVAIFFPLAVKRFRDLSR"
     gene            complement(11658..12596)
                     /locus_tag="GR131_RS31425"
                     /old_locus_tag="GR131_31425"
     CDS             complement(11658..12596)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008406749.1"
                     /locus_tag="GR131_RS31425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_31425"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_159313817.1"
                     /transl_table=11
                     /translation="MSDRDLAIVVEGLRKKYKDKQALDGLDLTVRAGTVQGVLGPNGAG
                     KTTAVRIMSTLLRADEGRVEVAGIDVRTRADDVRSQIGLLGQNAAVDEELSGRQNLEMF
                     GRLYHLGARRAGARADELLEQFGLTETGAKAVKQYSGGMRRRLDLAASLISRPQVLFLD
                     EPTTGLDPRGRTEVWNAVRSLVGGGTTVLLTTQYLEEADQLADQIAVINRGQVIAEGTA
                     DELKTKTGGDRIDVILHDVAQLERAASLLPGAVDKDEDRRMVSASISNRMAALTETVRA
                     LQEAGIEAEDIAVRRPTLDEVFMHLTMEEAA"
     gene            12766..>13115
                     /locus_tag="GR131_RS31430"
                     /old_locus_tag="GR131_31430"
                     /pseudo=""
     CDS             12766..>13115
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019070233.1"
                     /locus_tag="GR131_RS31430"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="GR131_31430"
                     /product="PadR family transcriptional regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPPIRLLNLGAGHQHGRAHGHQVRNDLEYWGPTTGRAPSRARSTT
                     PSSRWRSRGCTSPTRSRRAPQAARPAWNTSSTSRAPRSTSDCCATP"
     gene            complement(13595..14862)
                     /locus_tag="GR131_RS31435"
                     /old_locus_tag="GR131_31435"
                     /pseudo=""
     CDS             complement(13595..14862)
                     /GO_function="GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018841907.1"
                     /locus_tag="GR131_RS31435"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_31435"
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MAELGHEVLGMDIDPDKVATLNAGRAPFFERGLDELLAKHTASGR
                     LRFTTSSAETAAFADLHFIGVGTPQKPGEMAYDLTHLFAATRQLAPPT"
     misc_feature    complement(14341..14343)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(14988..15431)
                     /locus_tag="GR131_RS31440"
                     /old_locus_tag="GR131_31440"
     CDS             complement(14988..15431)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010636474.1"
                     /locus_tag="GR131_RS31440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_31440"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_159313818.1"
                     /transl_table=11
                     /translation="MDSQTLPDEPSAAEPRGAVAIITNRRGELLLHLRDNIAGIAWPDH
                     WSLLGGGCDPGEAPAAAIVRELDEEAGLAVDDLAELFETKDGAGSGQIITFFSGTWNGD
                     EQALPLAEGIKLQFFPPEHLPVLTIPPFIRHGIHRHLAARPRA"
     gene            complement(15460..16266)
                     /locus_tag="GR131_RS31445"
                     /old_locus_tag="GR131_31445"
     CDS             complement(15460..16266)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.4"
                     /locus_tag="GR131_RS31445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_31445"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_159314024.1"
                     /sec_met_domain="Asn_synthase (E-value: 9.8e-28, bitscore:
                     96.3, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHALDYPMGNASTFSEHMAYRAIAERGIQVVAGGMGPDEFLMGYV
                     RHALVLFGPKAVLGAGMESYRPLASKLLHPVGEPLDSAEAIVRLILRGQDPDAHLHQVV
                     ADPLARAGGDLARGLTLADLATAWRPLVMTSDKLASAFTLERRSPFQARDLVEFCYRLP
                     VEHKIGDQAAGKRILRDAAKALGLPREVWDSRDKLGFASPVPSWLTGPLEPWATAQISS
                     ALDQAPRSLRPLLAGGLKPGGRFDRPRMQSLMAAAWFNDQPVETAA"
     misc_feature    16542..16558
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.2"
                     /tool="antismash"
     gene            complement(16867..17682)
                     /locus_tag="GR131_RS31450"
                     /old_locus_tag="GR131_31450"
     CDS             complement(16867..17682)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013828.4"
                     /locus_tag="GR131_RS31450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_31450"
                     /product="ATP-binding protein"
                     /protein_id="WP_159313819.1"
                     /transl_table=11
                     /translation="MSVEVIIFMTTAVILPLLLTEFGDWCPWLAKRLAQWTAQRLGDAQ
                     AAERYSEEWLAELRHLPGKLSHLLTATSYLLALPRIRWSLRAARLMTPTGPTLDELLPT
                     RVPIYWDPRGANMNWGHQADAAYQLLRAILNDDLQVRNRMHFLVGPVGCGKTVVAHWLH
                     EHFVRDGKKIHYVWAHAWVNRERYIHVSSRMRDRLVQASQEVDLLVVDEADQATVEALE
                     ALRLPCPILVLARSHGELGEISRLPANAGTVVNMGPILDSWLQARPNTP"
     gene            complement(17679..18008)
                     /locus_tag="GR131_RS31455"
                     /old_locus_tag="GR131_31455"
     CDS             complement(17679..18008)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015513.4"
                     /locus_tag="GR131_RS31455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_31455"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_159313820.1"
                     /transl_table=11
                     /translation="MSYPFRVTDATVDVVEALLSGDDELYGLKIAKTIGRPSGSVVPIL
                     MRLEACGWVLSEWEQNESARGPRRRFYRLHADRVGEARRLVNERKPASSTVPSGILRPG
                     LGGAR"
     gene            complement(18018..19727)
                     /locus_tag="GR131_RS32475"
     CDS             complement(18018..19727)
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015422.4"
                     /locus_tag="GR131_RS32475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helicase associated domain-containing protein"
                     /protein_id="WP_236570863.1"
                     /transl_table=11
                     /translation="MRLGPLQDETNLSYLDRLADRYRLGVRDPIPALLQVGGSLFKGYR
                     TDGEVYLNAETRARVSAFCRVPEKILQRALPAWTTQEPLSPDGASAAGRFRFGSVVPAA
                     GEGCRLCTAARTGRTKPARLYLKPHTRICPRHGRWMLGTHWIDGGPADIEQVDLTGLPE
                     MVTAHRRHLDLLRHRPDAVRAFEVAHAVVVSWWTQQWSEEEQWPRRALRLSPPSVDPGW
                     WRLLARDAVTYPETVPSPSPPSSPTNAPGSGCSPILASICPTRSLTCPLWSANWRGSRG
                     GRGLPSGSPRPRPVLCCSGCSTAHGPTQTQPTRTGCGHCTWRTGPGPSPANSPPTATPH
                     SSRRRLRAVDGCTWGFGTGRIRRSTTGMAHARAYAAAHGHLATPIGERFNGFALGRWLS
                     NHRKFPAMPPEHVAELEALDPWWRPPWTVMWQRSYYEARDHARAWGGLRPEHGFPTTSF
                     GLGEWLYNQCPAYDELHPAQQRLLADIGLTPESARAARPRRKHMASQFQRALACARAFA
                     EANGMLVNATTDTVQDGLKLGQWLANQRSNPASCPDWWPHTGDALAFPSLVS"
     gene            complement(20280..21236)
                     /locus_tag="GR131_RS31475"
                     /old_locus_tag="GR131_31475"
     CDS             complement(20280..21236)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006375037.1"
                     /locus_tag="GR131_RS31475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_31475"
                     /product="TniQ family protein"
                     /protein_id="WP_236570698.1"
                     /transl_table=11
                     /translation="MRRTDVTACTAVAAAPAQRAVLTTEVWLRIPSAAPGVLRVRPLPG
                     EATASYVQRLAGTYQLTLSQLLDGVGITLHSHGTLPAAELHLNHNAARRLAALARFPLP
                     HLKHALPHLALPSDAHDTEAAAHWKRLEAAQPPVRACTLCTRHRSHDTTDTAWAHTAPQ
                     RLVCPRDQQAAPDPRLTSTVRTWAVPELVAAHHAHQRLLRRPRALTAWTTARAITTRWY
                     DHQQHLTHRWHTRLARLCATNPHLTTTGSASPTLLARDLVTYPETVALAGALAALPNQP
                     HRDTGKALNVIAHRLGLPRLPLNASDPIRVFLTHTRH"
     gene            complement(21233..22219)
                     /locus_tag="GR131_RS31480"
                     /old_locus_tag="GR131_31480"
     CDS             complement(21233..22219)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010069772.1"
                     /locus_tag="GR131_RS31480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_31480"
                     /product="ATP-binding protein"
                     /protein_id="WP_201305728.1"
                     /transl_table=11
                     /translation="MTTWDGFHAFVTAPVAAPPPPGAPPRSLEERLAYHSRFVTVRTPA
                     IDALAKNVRTLMILGRHQAVTARPSLIVTGPAGAGKTTALLQVGRACHLAHTRRHGAAA
                     TAGQAPVAYVLVPPAASAKTLAIEFARYLGIPITAGMSQAQITNAVCHTYTAARVQLVL
                     IDEIHRLNPRTTTGAQSADLIKDLTERIGATFVYAGIDVTTTPLFTGVRGAQLAGRASL
                     IDCDPFPARLGDEEPFRDLITAMEGALDLRHHRTGTLPKLAPYLHERTAGRIGSLARLI
                     RQAAITALLDGTERITKTTLDTIRLDHLAEQHYQPRARPRSRSTSTP"
     gene            complement(22336..24486)
                     /locus_tag="GR131_RS31485"
                     /old_locus_tag="GR131_31485"
     CDS             complement(22336..24486)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010069771.1"
                     /locus_tag="GR131_RS31485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_31485"
                     /product="Mu transposase C-terminal domain-containing
                     protein"
                     /protein_id="WP_236570697.1"
                     /transl_table=11
                     /translation="MGGTHGKSQRPVVEVGAHITYRGQTWQVAALQGQQVYLVQEDGAE
                     MSLLLGRLFADPGFEVVGGRAPEVVPQWGLFETVPVAAQQRALAWLPHIREVETGWPHP
                     EGGREGQAMRPEYDPERWTLAQRDAAKAKELAALGFARVTRTTVERMRHVYRKQGLWGL
                     VDKRTVPARGRHPTGYADERVVAAVLEALRRQRGRSKGTVKGLQVVVGQILEDTHGRGV
                     VEMPSRSTFYRLVSVLADPADRPGRPARTATAPARASSAPVVLRPGEQVQIDTTRLDIM
                     TVLEDGSLGRPELTIAVDVATRSILAAVLRPHSTKAVDAALLLAEMAVPHPARPTWPSA
                     LHLSRAEVPYERMLSLDERLEGAAARPVVVPETIVVDRGKIYLSQGFVAACETLGVSVQ
                     PAPPRRPQAKAVVERTFGAINDLFCQHVAGHTGSNPQRRGVATEAETRWTIPQLQDFLD
                     EWITCGWQNRPHDGLRHPVLPKSALTPNQMWAVLITISGYVPVPLSGADYLELLPVRWQ
                     PITERGIRLDYRTYNHDILDPHRGQRSPVASKDGKWEVHHNPHDARQIFVRLTDGHLHE
                     VPWIHLDHVHQPFNDALWRDIQTKVEQRGDRDQHEADLADALDQLLRRTRHPAETEQKT
                     RRRRARSGTAAQLPDLPGQRRPLDSETAPAPAPDWNESLDDLISVDTAAETGTSEPNGM
                     GVLPAEAGGYGLWDAEAEAEQW"
     gene            complement(24492..25298)
                     /locus_tag="GR131_RS31490"
                     /old_locus_tag="GR131_31490"
     CDS             complement(24492..25298)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005477251.1"
                     /locus_tag="GR131_RS31490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_31490"
                     /product="TnsA-like heteromeric transposase endonuclease
                     subunit"
                     /protein_id="WP_236570696.1"
                     /transl_table=11
                     /translation="MQQAAAGGDGAGIEAAFVTAAGRLTQLLWDQAAASVRFEDVAPVS
                     AFPVVPGRRWGPGWWWSATTGRHVVHGSAAMRTQLMVLDRNPDVTGLAARPVRLLWRDT
                     ADGRARSWVPQLFARYADGTGLLADCPSSPTAGGERAQRARMILEAACARVGWAYRRLE
                     PPPAVVAANLRWLAGYRHPRNQGPPGLQAALSEAFAGPRPLADGTAAVGDPLQVLPAVY
                     HALWCGHLTTPLDEPLQEEALVCADAERNGGGVEKRLDASGGPGKG"
     misc_feature    25516..25536
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 19.77"
                     /tool="antismash"
ORIGIN
        1 ggccgggagc tgagccgaca gcctcactct cccgagtgga ttacgcagag cgggagttgg
       61 agagcgacgg gtccgccagg cgcggacgcc gcagccgggg gaggatgcgg ggcgttcgcc
      121 aggaacgcct ctcggccgag gggatcgccg ccggccgccg gggccctccg cagacgggga
      181 accggggacc ggcaccctcg cgcacgggag gacactcccg ccccgaaagg aatgggccat
      241 gcgcgtcgcc cgtccgctgt ccctcttcgc cgccctctcg atcgccctcg cgggtgccgc
      301 ggccaccgcc accgcggcac ccgccccggt ccccgaggcc gccgctgccg gcagcggcta
      361 cgccgccccg accatgctgc actgcaagct gaacgtccgc tccgccacca agtcctccgc
      421 gaccgtgctc cgcacgcttc gcaaccgcaa cggcaactgc ccgggcaagg gcggccacga
      481 ctccgtcccc tgctggctga acaagtgcgg cggcatcacg gcgggcggca gctacacctg
      541 ccagtcgggc ggcaagtcct acaagagctg gctccccgtg aagcaccagg gcaagcgcgc
      601 ctgggtcgcg atcaagtgcg ggacgtacgt gaccccctga gccccgccgt ccggccccac
      661 ccccggttgc ccgatgtccc acaggccccg aatgccggga aatccatcct ccgcaaccgg
      721 gggttgaccg atgcgtcacg gctctctagg tttctcgcaa cctgctggta tatcgattaa
      781 ccagcgtcgt cgccccttgg ttggagacat ctcgctgtgc gctcacctct gagtcggcgc
      841 ggcttcctcg ccgcaggctc cggcctcgcc gctgccaccg ccttccccgc cctggccggg
      901 tgttcctccc tcgcctcggc cgattccgat ccggggaccc tcgtcgtcca cacccagctc
      961 ggcaccaccg cgccggggtc gcccacctac cgggcgctgg tcaaggagtt ccacgcggaa
     1021 caccccggcc tgcggatcaa gaacctggtc aacggcgacg acctcccgca ggtgtacgag
     1081 acctcgcggc tggcccgcaa ggagccggac gtcgtcatgg tcaacctcta cgacaagacg
     1141 ctggcctgga ccgagctcgg ggcgaccctc gacgtcaagg gatacctgga cgactggggc
     1201 ctgcgcgagc gggtgctgcc cgccgcactg aaggagtgga ccgacgacga ggggcggctg
     1261 cgcgccttcc cctacttcgc cgccaactgg cccgtcgcct tcaacaccag cctgctggcg
     1321 cgcgccggca ccggttccgt ccccaccacc ggcgaccagc tcctcggcgc ggcccgcaaa
     1381 ctgcgcgcca agggcatcgc ccccgtgacc gtcggcggca acgactggac cgggcagaag
     1441 ctcctcgccc agatcatcca gaccttcctc acccccgagg aagcccgcaa ggtctacgcg
     1501 agcggcgact tcggcggccg ccgggtgcgc gagggcatcg actacttcgt cgagctgcga
     1561 gatgccggcg tcttcgccga caaggcacaa ggactcacct cggacaccat gaccacgcag
     1621 tacaacaccg aggccgccgc gatccagtcc gcgatgtcct ccgcgctggc caaggtcccc
     1681 gagcggaccg ccgcgcacag cgaggtcggc ggctggccgc tggccccggg agccgcccac
     1741 gccaagccca ccatcatgcg gtcgtacacc ctcatcggct tctggatcag ccccaacggg
     1801 gcgaagaaga tctccgcggt cgagaagttc ctgcggttca tgtaccggcc cgagtccgtc
     1861 tcgcgcttca tcaccgagag cggccgggac atggccctgc ggaccgacac cgtcagcaag
     1921 gacttccccc tggtggccgc cgcgcagcgg ctcggcgacc aggtcggcca ggtgctcctg
     1981 cccgacctgt acgtcccgcc gaccgccacc cagccgctga tcacggccac cagcaccgcc
     2041 ttcacccgcg gcaccagcgc ggccaccgtg cgctccgccc tcgaatccgc ctaccgcacg
     2101 ggctgacccc gcgcgcccga gtcccgaggg gattccccat gacgttgctc tcctccgccc
     2161 cacccggcgc ccccgccacc cggagcgctc cgcaggcccc cggccgcaca ccccgccgca
     2221 agcagggcgg agtcatcctc gccgtcccgg cgctggcctg gtacctgctc ttcatggtcg
     2281 gcccgctggt cgccatcttc gtcatcgccg ccctgcactg gcccggcatg ctccagccgg
     2341 tctccttcgc cggactcggc aacgtccgca ccgtcctggc cgacccggtc ttcaccgacg
     2401 ccctcgtcaa caccggcatc cagctggccg tcgccctgcc cgtgatgatc gtcggcgcct
     2461 acatgctggg ctactacgtc gcgcagcgcc caccgggcca ccggttcctg cgctacctcc
     2521 tcttcatccc cggcctgatc tccacccccg ccaaggcgat ggtcttctac gccgtcctct
     2581 cgcccgacgg cctgttcaac ggagccctgg acaaggccgg cctcggctcc ctgaccgacg
     2641 cctggctcgc ctcgccctcc accgccctcg cctgcctgat cgtgctggac gtgtggagcg
     2701 gcatcggctt caccgccgtc ctcttcgccg cccggctcgg cagcgtgccg gacgaggtcg
     2761 gcgaggcggc gcagctcgac ggagccggac actggcgggc catgtggcgc atccacttcc
     2821 cgatgatccg cgacttcgtc ggcgtcgtga cgatgctcca gttcctgtgg accctgttcg
     2881 gctccgcgca gaacgtcctg ctgctcaccc agggcggccc gggctcctcc tcgacgaccc
     2941 tctccttcct cgtctaccag aaggcgttca tcgcggccga cctgggctac agccagaccg
     3001 tgggcgtctt cctgttcctg gccggcctgg ccgggctgct gaccatccgt cgcgtcttcc
     3061 gccagaacta ctgatcggag ccggtcccat gaagttcgga aggtcctggc tgcccgccca
     3121 cctcctcgcc tggctgtacg cggcgctgct cctcgtcccc ctctactacc tgctggtctc
     3181 ggccttcaag accaacgacc agatattcgg ctcccccttc gccctgccga cctcgctctc
     3241 cccgcacaac ttcaccgagg cgttcacctc cgccgacctg ggagccgcgg tcgtcaactc
     3301 cgtcctcgtg acggcgctcg ccctcgcact gaccctgggc ctcgcgatcc cggcggcctt
     3361 cgccctcgcc cgctcggacg gacggctcgg ggcgttcgtg gaacgcgtct tctccctcgg
     3421 cttcctcgtg ccgaccttcg ccgcgctctt ccccacgttc ctgctcgccg cctccaccgg
     3481 cctcttccac acccgggcct tcatggtgct gttcctgccc gccacggcga tgccgctgtc
     3541 ggtggtgatc ctggtgcagt tcatgcggac catcccgcgc gagatggagg aggcggcccg
     3601 gatggacggc gcctccacct tcgccgtcct gcgccacgtc tacaccccga tgtgcatgcc
     3661 gggcatcgcg acgatcctgc tgctgaactt cctgaccttc tggaacgagt acctctactc
     3721 actcgtcatc atcggccccg accccggcct gcgcaccgtg caggtcgccc tgcccacact
     3781 caagtccctc accggcaccg actacggcat cctgaccgcg ggcacggtcc tcaccctggt
     3841 ccccgtctgg gcggtgtaca ccgtgctgca gaaacgcatg caacaggcac tcgtcagtgg
     3901 ggcggtgaag atgtgaagga acgtctcgag gggcgaccgg gccgaagcgc gcccggcaac
     3961 gggacacggc cgaccatcaa ggcggtggcc gcggcggcgg gagtctccac cgccacggtc
     4021 tcccaggcgg tcaacgacac aggccggata tcggaggcga cccgccgccg ggtgctcgcc
     4081 gccgcggccg aactgggctg gtcgccgagc gccccggcca ccgcgctgcg cagggccagg
     4141 acccggacga tcgcgctcgt ggtacgccgc ccgaccgacg tcctgggcgc cgacccccac
     4201 ttcagcgaac tcatcaccgg cctggagggc caactggccc cccggggcta cggcctcctg
     4261 ctccacctgg tccccgacat ggccgaggag agcgcactgt acgaacggct cgccgccgaa
     4321 ggccgcatcg acggcgccgt gctgaccgac gcccgcgccg acgacccgcg ccccggactc
     4381 ctcaagggcc tcggcctgcc cgccgtcctg ctcggcacac cggaccccgc cgcacccgtg
     4441 cccggggtcg gcctcggaca gcaggacgcg ggcgtccggg aagccgtcac ccacctgctg
     4501 aaccacggac accggcgcat cgcctacgta gccggccccg ccgacctcgt ccactccggg
     4561 ctgcggcgcg cggcgttcga gagcgccctg gccgaggcgg ggctgcgccc cgtggccgta
     4621 cggcacaccg acttcaccga ggaggccgcc gtcaccgtca ccgccgaact cctcgcccgc
     4681 ccggaccggc cgaccgccct ggtcttcccc aacgactcca tggccgtctg cggcatgggc
     4741 gcggcccagc gcgccggact gcgcgtcccc gaggacgtct ccgtggtcgg ctacgacaac
     4801 ctgccgctcg gccggtggct gcacccccgc ctcaccacgg tggaccagca ggtccagcgg
     4861 gtcggcgcgg ccgccgccct caccctcctc gccggctgcg gcgaagaagt cccggccccc
     4921 ctcctcgacg gccggccccg cctggtcgtc cgggagtcca ccggccccgc ccccaccggc
     4981 cggccatgac ccccacctcc cgcaccaccc gcgggccgcc gcgcccccag ccccaccgac
     5041 ccaccgaacg tgtacaccga aagcatccga gaaggatcat gcgacgccac agcgcccagc
     5101 tcacccatga ccacgccgta ctgccctggc tcggcgccaa cttctggtcc cgcaccggcg
     5161 gccccctgat gtggcgcgac tacgacccga agaccgtgcg cgaggaactg gccgtcctgc
     5221 gcgagcacgg cctgacgatg acccgctcct tcttctactg gcccgacttc cacccggagc
     5281 cctcccggat cgacgaggaa ctctgcgacc gcttccggga cttcctcgac gcccacaccg
     5341 aagcggggat gggaaccgtc ccgaccttca tcgtcggcca catgtccggc gagaactggg
     5401 accccgtctg gcgcgggggc cgggacctgt acgaggacgt gtggctggtc ggacggcagg
     5461 cctggttcgt ctcccagatg acccggcgct tcaaggacca cccggccgtc accggctggc
     5521 tcatcaccaa cgagatgccc ggctacggcc gcatctacca ggagaacccg ccctccggcg
     5581 acgtggtcac cgcctgggcc cagttcatgt gcgacgccgt ccgcgccgcg ggcggcaccc
     5641 agcccgtctc gctcggcgac ggcgcctggg gcatcgaggt caccggccgc gacaacggct
     5701 tctcgctccg cgacacggcc gagtacgtcg acttcgtcgg cccgcacgtc taccgctccg
     5761 acaccgaccg gccccgccag cactaccgcg ccgccttcga gtgcgaactc gccgccgtca
     5821 ccggccagcc ggtcgtcctg gaggagttcg gcctctccac cgacaccgtc tccgccgcca
     5881 acgccggcat cttctaccgc cagaccctgc acaactccct gctcggcggc gccaccggct
     5941 ggatcgcctg gaacaacacc gactacgacg ctctgtggga ccgctcgccc tacgaccacc
     6001 accccttcga gatgcacttc ggcatcaccg acagcgaagg acgccccaag gagccgctgc
     6061 gggaactcgc cggcttcgcc gaagtgctgg aacgcgtcga cttcgcccgc tgccgccgca
     6121 ccgacgccga cgccgccctg gtcgtccccg ccttcctcga acgcggctac ccctacagcc
     6181 gccccgccga ccgcccgctg atcttcacct ccctccacca gggatacgtc gcggcccgcg
     6241 gcgccgacct gcccgtcgcc ctcgcccgcg aggccgacgg gctggccgag gacgccgcgc
     6301 tctacctgct gccctcgacc cgccagctca ccacccgcac ccgccgcgcc ctggaacgcc
     6361 gcgcccgcga aggagccacg gtctacctgt cgttctgctc gggcgaacac cccggcacgc
     6421 gcggcccctg gttcgacgac ctggacggcc tgttcggcgt cgaactccag ctctcctacg
     6481 gcgtcgccga gccgatcgag gacgacgtac tggagatgac cttcaccgag gagttcggga
     6541 ccatcaaggc gggcgagacc ctgaccttcc ccgtcgccgg caacgaggac agccgcgcct
     6601 acctgcccgt ggtccccgac ggcgcccgcg tggtcgccac cgacgcccac ggccgcccgg
     6661 ccctgctgcg ccacgacacc gggcagggcc gaaccgtcct cgccacgtac ccgctcgaac
     6721 acatggcagc ccgcaccgcc cgcgtcaacc ccgagcagac acaccgcctc tacgccgcgc
     6781 tcgccgagat cgccggggtc gtgcggcccg tcacggtgga cagcccgtac gtcgccgcgg
     6841 acaccatcgt gcacgaggac ggccgccgct tcgtctggct ggtcagccag tccggcaagg
     6901 aactgaccgt ccggccgtcc gccgacggca ccctgcacag cctggacgac ggcgacccgg
     6961 tgcgggacgt gaccctgccg ccgtacgggg tgcgcgtcct ggaacagcgc tgaccccctg
     7021 ccccctcttc accccgtcac gccgtgaggt caggagaccc agccatggcc gaccccctct
     7081 accgcgaccc caccgccccc gtcaccgccc gggtacgcga cctcctcgcg cgaatgaccc
     7141 tcaccgagaa ggtcggacag gtcaaccagc ggatgtacgg ctggcacgcc tacgagcgca
     7201 ccccgtccgg gtaccggctc accgaggcgt tccgcaccga ggtcgcggcg ttcgacggga
     7261 tgggcgcgct ctacggcctg caacgcgccg acccctggtc gggcgtgacg gccgaaacgg
     7321 gcatcggcgc ggcggacggc gcccacgtct ccgacaccgt ccagcgccac gtcatcgaca
     7381 acacccgcct gggcatcccg gtcctcatgg tcgaggagat gccccacggc caccaggcac
     7441 tggacggcac cctgctgccg gtgaacctcg ccgtcggcgc cacctggaac ccggagctct
     7501 acgaagaggc cgtcgccgcg gccgccgccg agctacgggc gcggggcggc cacgtggcgc
     7561 tcgtctccgc actcgacctg gtgcgcgacc cacgctgggg gagggcggag gagtgcttcg
     7621 gcgaggaccc gtacctggcg gcacggttca ccgaagcact ggtgcgcggc gcacaggggg
     7681 caccggccga gcggatcgcc cccgaccgtg cggccgtcgt gctcaaacac ttcgcgggcc
     7741 agggcgcgac gatcggcggc cgcaacagcg cggcgaccga actgggcatc cgggaactcc
     7801 acgagatcca cctcgaagcc gcgctcgcgg gcgtacgggc cggggccgcc ggtgtgatgg
     7861 ccgcctacaa cgagttcgac gggctgccct gcgccgccag ccgcgacctg ctgaccggca
     7921 tcctgcggga ggagtgggga ttcgacgggg tggtgatggc cgacgggctg gccctggacc
     7981 ggctggtgcg cctggccggg aacccggtca cggccgcggc gacggccctg tcggcgggct
     8041 gcgacctgag cctgtgggac gactgcttcc cgcgcctggc ggaggcggtc gaccgggggc
     8101 tggtcgagga gagcgcgctg gacacggcgg tggggcgggt cctcgcgctg aaattccggc
     8161 tcggtctgtt cgagcagccg tacaccggcg agcgaccccg cgtcgccgca ccacgtgagc
     8221 tgagccggcg cctcgcccag gagtcggtca cgctccttgc ccacgacggg gtgaccctgc
     8281 cactgcctgg ccgggcacgg gtcgcggtgc tcggcccgaa cgcagattcc gtaccacagc
     8341 agctcggtga ctacaccgca ccccagcgcc ccggcgtggg cctcagcctc ctcgcgggac
     8401 tgcgggcggc cgcccccgca ggtacggaga tcacctacgc ccgcggctgc gacctcgtcg
     8461 gcgcggaccg gtcggccctc ccggaagcgg tggccctcgc ggcggactcg gacgtcgcga
     8521 tcctcgtact cggcgggtcg agcgcccgcg ccgccgaaac ccacttcgac gccaacggcg
     8581 ccgcccaggt caccggcgac cccgacggaa tgacctgcgg cgaaggcgtg gacctggccg
     8641 acctcgcgct cccggagggc cagtcggcgc tgctcgacac gatcacggct atcggcgtac
     8701 tcgtggtggt cgtcctggtc caaggacgcc cgcaccccct cccggacctg accgggcgcg
     8761 cggcggccgt gctcagcgcc tggtacccgg gcccctgggg cggccaggcg gtggccgacg
     8821 tcctgctcgg cacggcggaa ccgaccggcc gcctcccggt gtcggtaccc cgcaccgccg
     8881 cccaactacc ggtcttctac aacgcgaagg accacggcta ccgcggctac gtcgaccagc
     8941 cggccaccgc ccgccacccc ttcggacacg gcctctccta caccacggtc gagtacggcg
     9001 cgccccgcct cacacgcccg gccgccacgc tcgcggagtt cgacgaggcc ggcgagacag
     9061 gcggcacgcc cccgctggtg tgctcggtcg aggtacgcaa caccggtgac cggccggtcc
     9121 gcgagaccgt ccagctctac gtccgccgcg tgctcggcgg cacctcctgg ccccgggtac
     9181 gcgaactgcg cggcttccgc cacacccagc tcgcccccgg ggagacgtcc gaggtctcct
     9241 tcaccgtcga cgcccggacg ctggcctcgg tctcccgctc gggaaagcgc gaggtagagg
     9301 caggcgagta cgccatcgag accggcccct cctccgcccg cacccagccc gcccgactca
     9361 ccgtccacga cgagcgcggc accaccttcc cgggaccatg accggccgga caagtcctag
     9421 ccggcgggct cggggtggtg gtgtgtgctg tccttacgca gttcgtgggc gacggcctag
     9481 ccacgggcgg gggtgatctc ggtcgtggcg aggatgggcg gaaggacggt actggggagg
     9541 atgtggtgca gcagggcggt cacccgagtg aggatgtcct ggtagtcgct caggacctgc
     9601 gacatggcct gtacgccggc gaaggggccg accaggatgt cggctgtctg ggcgacgtgg
     9661 atgtggggga ggagttcccc ttgcgcctcg gcctgttcga ggagttcccg gatgacggtt
     9721 ccccagtgcg tgaaggctcc ctgacggttg accctcttgc gcttcccggt ccagtgagag
     9781 ccgtaccccg gcccggacca tggggtcgtg ctggaggcgg tgtgcgtgca ggaggacggt
     9841 gtcggtgagc tgctggacct tactggcacg gtcggggacc ggaaggtgct gagcctgctc
     9901 gcggaggatt ccctgggcca gctcctccgg agcatccccg cgcgtgcggg gccgacactt
     9961 gctgacctgg gaggttaccg cgagggtgcc tcattttcat tcatatgcgt cgccctttcg
    10021 gtacgggagg tgcggcgagg gcgccggccc aggggcggcg ggggtcgggg cggtcgcggc
    10081 cggacagccc gaatgcgccg ttctcggtcc acacccacgc atgtgcctcg gtgggcaact
    10141 gccgtgcgcc cagcacccag tggacccgcc gaccgcagag cgccagggcg aggaccgtcg
    10201 cgagcgagat ttccatgcag gcgatgcggc cccggtacca ggccgggcgg attgatgggg
    10261 gaggggaagg cggcgtttcg aagtcaagca ggggggccgc acgccgtcgg ccccgacata
    10321 cctagactcg aacgcatgtc cgatctgccc gccgacctgc cgtgcctgca tgtgctgcgg
    10381 acgtggcacg cgatgtggct ggcccggatc gacaaggcga tcgcgacagc cgagcagcgg
    10441 gaggccgaga cccggcgcgg cgctgaggtg cgcccgccgc tcgccggggc ccgcgtccgg
    10501 ccgctcgaca ccgagcaggc ccggcaggcc ctcgtcgatg tgcaggcgtg cagcatgtgc
    10561 cgaccggaca cggacctcgg cctgctgtag gtcagcgggc gtttctacaa cgcgggtagc
    10621 cggggtcgtc cttgccagtg ggatcaggtc gtggctgtcg gcggcgtgtg gcacagggga
    10681 ggacgtggcg ggggtgtggg gcatgttccc gtttcctcca aggctgtggt gcggccggaa
    10741 gggtggtacg actgtggcac cgccggaagc ggcccccagg ccccgacggg ggggcagggc
    10801 cgggggccgc gcatggggtc agcggctgag gtcccggaac ctcttgaccg ccagcgggaa
    10861 gaagatcgcg accaggagca gcggccaggc caccgccagg agctccgcgt gggtcgcggc
    10921 ccatgagtcg ccggccgcgc tctggttgcc gaacaggtcg cgcaccgcgg ttgccgtcgc
    10981 cgacatcggg ttccactcga cgaccccacc gagccaggcg ggcatcgagg cgggcgtggc
    11041 gatggcgttg gagaggaagg ccatcggcca gaccaggatc tgcacggcct gcaccatctc
    11101 cggcttgccc gcgaccatcg ccaggtggag gccgatccac agcatcgcga accgcagcag
    11161 gagcagcagg cccacggccc ccatgaagga ggcgaagccg ttgttccacc gccagccgat
    11221 cgcggcgccg acgccgatca tcaccgccag gccgacgacc gactgcagca tgtcggcgat
    11281 gctccggccg accaggatcg agccggagtt catcggcatt gaacggaacc ggtcgatgac
    11341 gcccttgccg aggtcctgag tgaccgacag catggtcgcc tcaaggccga aggccatggt
    11401 catggtgagc atgccgggca ccaggtagga cctgaagtcc ccctcgacgc ccttgccgcc
    11461 gccgatcagg aagccgaaca tcagcagcat catcaccggg aagaccagcc cgacgaccac
    11521 ctgcacgggc tggcgcgccc agtgcgccag ctcgcgccgg gtcatcgtcc aggagtcggc
    11581 gaacgcccag ctcagcttcg atcccgttcc gtgcgtccgg ctcaccgggg ccgtcgtggc
    11641 cacatcatgg gtcgcagtca tgcggcctcc tccatcgtca ggtgcatgaa gacctcgtcg
    11701 agggtcggcc gacgcacggc gatgtcctcc gcctcgatgc cggcctcctg cagcgcccgt
    11761 accgtctcgg tcagggccgc catccggttg ctgatcgagg cactgaccat ccgccggtcc
    11821 tcgtccttgt ccacggcgcc gggcagcaga gaggcggcgc gctccagctg cgccacgtcg
    11881 tgcaggatca cgtcgatgcg gtcgccgccg gtcttggtct tcagttcgtc ggcggtgccc
    11941 tcggcgatga cctgcccgcg gttgatcacc gcgatctggt cggccagctg gtcggcctcc
    12001 tccaggtact gtgtggtcag cagtacggtc gtaccgccgc ccaccaggga gcgcaccgcg
    12061 ttccacacct cggtgcggcc gcgggggtcg agcccggtgg tgggctcgtc caggaaaagc
    12121 acctgaggcc gggagatcag cgacgcggcc aggtccagtc gccgccgcat gccgccgctg
    12181 tactgcttga cggccttggc gccggtttcg gtgaggccga actgctccag cagctcgtcc
    12241 gcccgcgctc cggcgcgccg ggcgccgagg tggtagaggc ggccgaacat ctccaggttc
    12301 tggcggccgc tgagttcctc gtcgacggcg gcgttctggc cgagcagccc gatctgcgag
    12361 cgcacgtcgt cggcgcgggt gcgcacgtcg atgcccgcca cctcgacgcg tccctcgtcg
    12421 gcgcgcagca gggtggacat gatgcggacg gccgtggtct tgccggcgcc gttggggccg
    12481 aggaccccct ggacggtccc ggcccgcacc gtgaggtcga ggccgtcgag agcctgcttg
    12541 tccttgtact tcttgcgcag accttcgacg acgatcgcca gatcgcggtc agacaaagca
    12601 ccctccttca gtcagtggat aaacttgact agtgatgtcg ccgtagggtc atcgacgttt
    12661 ggtcaaactt gattagtcgc gacgaaggta ccgcagatct aggactagtc aaacgtgtat
    12721 agaactcatc cgggcgcaac tgcgtacgag gagaggggca tgcccatgcc accgatccgg
    12781 ctgctgaatc tcggcgcggg ccaccagcac ggacgggcgc acggccatca ggtgcgcaat
    12841 gatcttgagt actgggggcc cacgactggt cgagcgccaa gccgggctcg atctaccacg
    12901 ccctcaagca gatggcgaag caggggctgc acatcgccca cgagatcgcg ccgagcaccg
    12961 caggcggccc gccccgcgtg gaatacgagc tcaacgagca gggcgccgcg gagtacttca
    13021 gactgctgcg cgacgccctg agctcgcacg agcagaaatc cgacgacctc tccgccggcc
    13081 gcggcttcat cgtcgacctg ccccgcggtg aggcaacacc ggtcaggcgt cgcaccccgg
    13141 agcaccccca caggtgcgcg gccgaccagc ccgtcatgaa gcccgtctac tgccccggcg
    13201 aagcatcccc gcgggtgcgg gactgactcg cgcggagagg acagctcctc atccgcgtac
    13261 ttcagacgat cagcggggta cctccgctcg cgcagagaag aggtcgtcgc gggagcatcc
    13321 ccgcgggtgc ggggccgaca cgctggctcc ccggctcaaa cacagcgacc agggagcatc
    13381 cccgcgggtg cggggccgac acttgctgac ctgcaacgtt atcgcgaagc cagcgggttc
    13441 tcattcactt gcatcgcgcc tctcgagacc actctcaccg aaagcaatcc ccgcagtcgc
    13501 gcggcccact tcagtttggc cgacggcgcc aacgtgaact gcggagcatt ttgcgggtgc
    13561 ggggctggcc gactcgattt gaaaggccag gtgttcaggg gcggccgagg gcgcggtggg
    13621 tccatccggc ggcctgccag cgggcggggt tgagggtgcc tcggccgtcg atgacgcggg
    13681 ggacggcgac gcggagggca aggtcggtcg ggtcgatgcg ggtgaactcg ggccactcgg
    13741 tgaggtggag cagtagttcg gcgccttcgg ctgccttgat cgggtgttcg gcgtagtcga
    13801 gttgggggtg gattttgcgg gcgttgtcga gggctttggg gtcggagacg gtgacgctgg
    13861 cgccggcttg gtggagggct tgggcgacgg cgagggcggg ggagtcgcgg atgtcgtcgg
    13921 tatcgggttt gaaggcggcg ccccagacgg tgatccgctt gttcttgatc acgccgttga
    13981 gctgttcgcg ggtgaggtcg agcatgcgct cgtggcggtg ggtgttgatc gagtcgacct
    14041 cgcgcaggaa gttcagggcc tggtcggcgc cgagctcgcc ggcgcgggcc atgaagccgc
    14101 ggatgtcctt gggcaggcag ccgccgccga agccgaggcc cggtcgcatg cctcgtcggc
    14161 cgatccgggg gtcgtgcccg agggcttcgg ccagcggctg gatgtaggcg ccggaggtct
    14221 cgcagacctc ggccatggcg ttgatgaagg agatcttcgt ggcgaggaag gcgttcgcgg
    14281 cggacttcac cagttcggcg gtggccaggt cggtgacgat caccggtgtg cccgacttga
    14341 taatcttgcc gtatgcgtgg cggatcatgg cctcggcccg ggtgttctcg ccggtgaagc
    14401 cgagaacgat tcggtcgggg tggagggtgt cctcgaccgc gtgggactcg cggaggaact
    14461 cggggttcca gcagacctcg ccctggtcgc cggcgggagc gaactcgcgc aggatgccga
    14521 tcacctgcgg ggcggtgccg accgggacgg tgcacttgcc gacgatcacg gtgggcctgg
    14581 tcaggtgggg ggggcgagct ggcgggtggc ggcgaagagg tgcgtgaggt cgtaggccat
    14641 ctcgccgggc ttctgcgggg tgccgacgcc gatgaagtgc aggtcggcga aggcggcggt
    14701 ctccgcggag gaggtggtga accgcagcct cccgctcgcg gtgtgcttgg ccaggagttc
    14761 gtccaggccg cgctcgaaga agggggcccg gccggcgttc agggtggcga ccttgtcggg
    14821 gtcgatgtcc atgccgagga cctcgtggcc gagttcggcc atcgcagcgg cgtgggtcgc
    14881 gccgaggtag ccgcagccga tgacggtgag cttcacgatc ggtgtccttc cgagaggggt
    14941 ggggccgccg gaccggcgcc agggcccctc tcgggaacag gggggggtca ggcgcggggc
    15001 cgggcggcga ggtggcggtg gatgccgtgg cggatgaacg gcgggatggt caggacgggc
    15061 aggtgctcag gggggaagaa ctggagcttg atgccttccg cgagcggcag ggcctgctcg
    15121 tcgccgttcc aggtgccgga gaagaaggtg atgatctggc cggagccggc gccgtccttc
    15181 gtctcgaaga gctcggccag gtcgtcgacg gccaggccgg cctcttcgtc gagttcgcgg
    15241 acgatcgctg cggccggggc ctcgccgggg tcgcagccgc cgcccagcag gctccagtga
    15301 tcaggccagg cgatgcccgc aatgttgtcg cgcaggtgca gcaggagctc gccacgccgg
    15361 ttggtgatga tcgcgacggc cccgcgtggt tcggcggcgg acggctcgtc ggggagagtc
    15421 tgggagtcca tctgctcacc gtagtgatcc gacagcccgt catgccgctg tctccaccgg
    15481 ctggtcgttg aaccaggcgg cagccatgag cgactgcatc cggggccggt cgaaccgccc
    15541 gccgggcttg agaccgccgg ccagcagcgg ccgcagcgaa cgcggggcct ggtcgagagc
    15601 ggagctgatc tgggcggtcg cccagggctc cagcgggccg gtgagccagc tcgggaccgg
    15661 ggaggcgaag ccgagcttgt cccggctgtc ccagacctcc ctcggcaggc cgagggcctt
    15721 ggccgcgtcc cgcaggatcc tcttcccggc cgcctgatcg ccgatcttgt gctcgaccgg
    15781 cagccggtag cagaactcga ccaggtcccg tgcctggaac ggcgagcgcc gctccagcgt
    15841 gaacgcggag gccagcttgt cgctggtcat gaccagcggg cgccaggccg tggccaggtc
    15901 cgcgagcgtc agcccgcggg ccaggtcccc gcccgcccgg gccagggggt cggcgacgac
    15961 ctggtgcagg tgtgcgtccg ggtcctgccc gcgcaggatg agccggacga tcgcctcggc
    16021 cgaatctagc ggctcgccga ccgggtgcag gagtttggag gccagcggcc ggtaggactc
    16081 cattccagcg cccagcaccg ctttcggtcc gaacaggacg agggcgtggc ggacgtagcc
    16141 catcaggaat tcgtccggcc ccattccgcc ggccacgacc tggatgcccc gctcggcgat
    16201 ggcccggtag gccatgtgct cggagaacgt ggacgcgttg cccatcgggt agtccagcgc
    16261 gtgcatgatc tccggcagcg cggcggcgaa gtcctgggcg gtcggctcga cgaccgccca
    16321 ggacttcgcc gccgatgttg cgggcgacga cggcggccgt cgcggactcg tccaggcggt
    16381 cctggccggg gtagcggacc gtgacgcaga cctgcgggcg catcaggtag gccagcatcg
    16441 ccgagtcgag cccgcccgag agcaggaggg cgaagtcggt gccgggggcc cgcaggggga
    16501 cgcgggcagc cagcagggtg gagaaccggg cgattgcggt cttgcagtcg ccttgccagg
    16561 gctcgagccc cccgagggtt cgccaggtct gctgggccag ggggccggtg gcgacgtcga
    16621 aggccagcag ggtggccggc gcgaggcgct gggtgccctg gaagggggtg tcgacgccgg
    16681 ccggcgtctc gatgctgcgc atctccgggc ggacgaccag aggggcggtg ccgtagccgg
    16741 tcagggtggt gacctcggag gcgaaggcga gccggccgcc gtccaagcgc cagtagagcg
    16801 gcttctcgcc gagccggtcc cacacggcct agtgctgatc accgtcggta cgccctggag
    16861 ggtggactat ggcgtgttgg gcctcgcttg caaccaactg tccaggatcg gacccatgtt
    16921 gaccacggtt cctgcgttgg cgggcagtcg actgatctct ccgagttccc cgtgactcct
    16981 tgcaaggacg agtatcggac agggcaggcg caaggcttcc agggcctcga cggtggcctg
    17041 gtcggcctca tccaccacga ggaggtccac ctcctgtgac gcctgaacca gccggtcccg
    17101 cattcgagaa ctcacatgga tataacgctc ccggttcacc caggcgtgag cccaaacgta
    17161 gtggattttc ttgccgtctc gcacaaagtg ctcgtgcaac caatgcgcca cgacggtctt
    17221 gccgcagcca accggaccga cgagaaagtg catgcggttc ctgacctgca ggtcgtcgtt
    17281 caggatcgcg cgaagcagtt ggtaggcggc gtctgcctga tgcccccagt tcatgtttgc
    17341 cccgcgaggg tcccagtaga tcgggacccg cgtcggcaga agctcgtcga gggtcggccc
    17401 ggtcggcgtc atcagccggg ccgccctgag agaccagcgg atgcgtggga gcgcgaggag
    17461 atagctagtt gcggtcagca ggtgtgacag cttccccggg aggtgccgga gttctgcgag
    17521 ccactcctcg gaataccgtt ctgccgcctg agcatccccc agccgctgcg ctgtccactg
    17581 cgcgaggcgt ttggccagcc aggggcacca gtcaccgaac tccgtcagca gcaacggcag
    17641 gatgacggcg gtcgtcatga agatgatgac ctcgacactc atcgtgcgcc cccgagacca
    17701 ggacgaagga tgccggaggg aaccgtgctg gaagccggtt tccgctcgtt aaccaggcgc
    17761 ctcgcctcgc cgacgcggtc ggcatggagg cggtagaaac ggcgccgagg cccgcgggct
    17821 gattcgttct gctcccattc acttagaacc caaccacagg cttcgaggcg catcagaatc
    17881 ggaaccacac ttccgctcgg ccgtccgatc gtcttagcga tcttcaagcc gtagagctcg
    17941 tcatcgccgg aaagtagggc ttcgacgacg tcaaccgtcg cgtcggtaac cctgaaggga
    18001 tagctcatgc cctaactcta gctaactaga gatgggaatg cgagcgcatc tcctgtgtgc
    18061 ggccaccagt cggggcaact ggccggattg ctgcgctggt tggccagcca ctgtcccagc
    18121 ttcagtccgt cctggacggt gtcagtggtc gcgttcacca gcatgccgtt ggcctcggcg
    18181 aaggcgcggg cgcaggcgag ggcgcgctgg aattggctgg ccatgtgctt gcggcggggc
    18241 cgagccgccc gggcgctctc gggggtgagg ccgatgtcgg ctaggaggcg ctgctgtgcg
    18301 gggtgcaact cgtcgtaggc ggggcactgg ttgtacagcc attcgcccag gccgaagctg
    18361 gtggtgggga agccgtgttc gggtcgcagg ccgccccaag cgcgggcgtg gtcgcgggct
    18421 tcgtagtagg agcgctgcca catgaccgtc catgggggtc tccaccaggg atccagcgcc
    18481 tcgagttccg cgacgtgttc ggggggcatc gcggggaatt tccggtggtt cgacagccac
    18541 cggcccaggg caaagccgtt gaaccgctcg ccgatcggag tggcgaggtg gccgtgagca
    18601 gcggcgtagg cacgggcatg ggccatccct gttgttgaac gcctgatccg acctgtgccg
    18661 aagccccagg tgcagccgtc taccgcccgc agccttctcc ggctgctgtg tggtgtcgcg
    18721 gtaggcggtg agttcgcggg cgatgggccg gggccggtgc gccatgtgca gtgtccacag
    18781 ccggtccgcg tcggctgggt ctgcgtcggc ccgtgcgcag tgctgcaccc agagcagcaa
    18841 aggaccggcc gaggtcgagg cgacccgctc ggcaagccac ggccgcctcg tgacccgcgc
    18901 cagttcgccg accagagcgg gcacgtgagc gagcgtgtgg ggcagatgct cgccagtatc
    18961 ggcgagcagc cgctgcctgg cgcgttcgtc ggtgaggagg gaggtgaggg cgacggtacg
    19021 gtctccgggt aggtgaccgc gtccctggcc agcagccgcc accagccggg atcgacgctc
    19081 ggcggcgaga gccgcagcgc ccggcgaggc cactgctctt cttcggacca ctgctgcgtc
    19141 caccaggaga cgaccacggc atgcgcgacc tcgaacgcgc ggacggcgtc cggccgatgg
    19201 cgcagcagat ccagatgccg ccggtgcgcc gtgaccatct ccggcagccc cgtcagatcg
    19261 acctgctcga tgtcggccgg cccgccgtcg atccagtggg tgccgagcat ccagcgccca
    19321 tgacgcgggc agatccgggt gtgcggtttc aggtacagcc gggcgggctt ggtacgcccg
    19381 gtgcgtgcgg ccgtgcacag ccggcagcct tctcccgcgg cgggcactac gctcccgaac
    19441 cggaaccgcc cggccgcgct cgccccgtcc ggtgagaggg gctcctgggt ggtccaggcg
    19501 ggcagggccc gctgaaggat cttttcgggc acgcggcaga acgcggagac gcgggcgcgg
    19561 gtttcggcgt tgaggtagac ctcgccatcc gtgcggtagc ccttgaacag gctcccgccg
    19621 acctggagga gtgcggggat ggggtctcgg acgccgagcc ggtagcggtc ggccaggcgg
    19681 tccaggtacg acaggttcgt ctcgtcctgc agcggcccga gccgcaccgg ccccggacgt
    19741 gccgctgctg tccgcggggg ctgcggtggt ggtggaagaa agtcgtgcat cagggagcag
    19801 aggtcgtttc ctggcagacc cggatgtacc ggcatccgag cagtggccaa acgggggagc
    19861 gggacggaca gttgaggcgg aacgcccccg gtcagggctg gcgttgcgag ggcgtccggc
    19921 ggcggtgcgg cgctcgggcc cgttgttcgg cggcggtgtc gagttcgatc tgttcgagca
    19981 gtttcttggt gaccttctcg gtgccgtcca tcagagactg tggcgggtca gtgatcttca
    20041 gagggctgga ctgctttggt ctggtgtttc gtctttgggg gtgggactcg ggacggctga
    20101 agcggttgcg ctggggcgtg gtgggcgtgg cttgggacgt gttcggtttg gttgttcggg
    20161 ggcgtggcct acggtccggt atttgtgtgg gattgatctt ggatttctcg ttggtgtggt
    20221 ggtgcgtcta taggcggttg cgctttctgg ggggggtgtg gggttccgga tggtgctggt
    20281 cagtggcgtg tgtgggtgag gaagacccgg atgggatcgc tcgcgttgag gggcaggcgg
    20341 ggcagtccga gtcggtgggc gatgacgttg agggccttgc cggtgtcgcg gtgtggctgg
    20401 ttcgggaggg cggcgagtgc gccggcgagg gcaacggttt ctggataggt caccaggtct
    20461 cgcgccagga gggtggggga ggcgctgccc gtggtggtca ggtgggggtt ggtcgcgcag
    20521 aggcgggcca ggcgggtgtg ccagcggtgg gtgaggtgtt gctggtggtc gtaccagcgg
    20581 gtggtgatgg cgcgcgctgt ggtccaggcg gtgagggcgc gtgggcgccg taggagtcgc
    20641 tggtgtgcgt ggtgcgcggc gacaagctcc ggcacggccc aggtgcggac ggtggaagtg
    20701 agccgcgggt cgggggctgc ttgctggtcg cgtgggcaca ccagccgttg tggcgcagtg
    20761 tgggcccagg cggtgtcggt tgtgtcgtgg ctgcggtggc gggtgcacag ggtgcaggcg
    20821 cggacgggcg gctgtgcggc ctcgagccgc ttccagtgcg cggcggcctc ggtgtcgtgg
    20881 gcgtcgctcg gcagggcgag gtggggcagg gcgtgcttca ggtgggggag tgggaatcga
    20941 gcgagggcgg ccaggcgccg ggccgcgttg tgattgaggt ggagttcggc tgctggcagg
    21001 gtgccgtggc tgtggagggt gatgccgacg ccgtcgagga gctgggacag cgtcagctgg
    21061 taggtgccgg cgagacgttg gacgtatgag gcggtcgcct cgccgggcag gggccgtaca
    21121 cggagtacgc ccggagcggc tgacgggatc cgcagccata cctctgtggt gagaacggcg
    21181 cgctgggcgg gggcggctgc gaccgcagta caggctgtga cgtctgtccg tctcacgggg
    21241 tgctggtact ccggcttcgg ggccgggcgc ggggttggta gtgctgttcg gcgaggtggt
    21301 cgaggcggat ggtgtcgagg gtggtcttgg tgatgcgttc ggtgccgtcg agtagcgcgg
    21361 tgatcgcggc ttggcggatg aggcgggcga ggctgccgat gcggccggcg gtgcgctcgt
    21421 gcaggtaggg agccagcttg gggagggttc cggtgcggtg gtggcgtagg tcgagcgcgc
    21481 cttccatggc ggtgatgagg tcgcggaagg gctcttcgtc gccgaggcgg gcggggaagg
    21541 ggtcgcagtc gatgagggag gcgcgtccgg cgagctgggc tccgcgcacg ccggtgaaca
    21601 ggggtgtggt ggtgacgtcg atgccggcgt agacgaaggt ggcgccgatg cgttcggtga
    21661 ggtctttgat caggtcggcg ctctgggcgc cggtggtggt gcgggggttg agtcggtgga
    21721 tctcgtcgat cagcaccagc tgtacccggg cggcggtgta ggtgtggcag acagcgttgg
    21781 tgatctgggc ttgggacatg ccggcggtga tggggatgcc gaggtagcgg gcgaattcga
    21841 tggcgagggt cttggcgctg gcggcgggtg ggaccaggac gtaggcgacc ggggcctgtc
    21901 cggctgtggc cgcagcaccg tggcggcggg tgtgggcgag gtggcaggcg cgtccgacct
    21961 ggagcagggc ggtggttttc ccggcgcctg ctgggcctgt gacgatcagg gacggccgtg
    22021 cggtgacggc ctggtggcgg ccgaggatca tcagggtgcg cacgttcttg gcgagggcgt
    22081 cgatggcggg ggtacgcacg gtgacgaacc gcgagtgata ggccagtcgt tcctcgaggc
    22141 tgcgaggcgg tgcgccgggt gggggaggag cggccacggg agcggtgacg aaggcatgga
    22201 agccgtccca ggtggtcacc gatcgctgct gcgcatcagt ggggtcgtcg gtggtgcttg
    22261 ccgcggcccc gggacgccgg gccgctgtcg acggggacct gcgggccgat gcatcgctcg
    22321 tgcccggtga ggcgttcacc actgctcggc ttccgcttcg gcgtcccaca gcccgtaccc
    22381 gcctgcctcg gccggcagca cgcccatgcc gttcggctcg ctcgtgccgg tctcggccgc
    22441 cgtgtcgacg ctgatgaggt cgtccagact ctcgttccag tccggtgccg gggccggtgc
    22501 ggtctctgag tcgagtgggc gccgctggcc tggaagatcg ggcaactgcg ctgccgtacc
    22561 ggagcgggct ctccgacggc gggttttctg ctcggtctcg gcggggtggc gggtgcggcg
    22621 caggagctgg tcgagggcgt cggcgaggtc ggcctcgtgc tggtcgcggt ctccgcgttg
    22681 ttcgaccttg gtctggatgt cgcgccaaag ggcgtcgttg aaaggctggt ggacgtggtc
    22741 gaggtggatc caggggactt cgtggagatg gccgtcggtg aggcggacga agatctggcg
    22801 ggcgtcgtgg gggttgtggt ggacctccca cttgccgtcc ttgctggcga ctggggagcg
    22861 ctggccgcga tgggggtcga ggatgtcgtg gttgtaggtg cggtagtcaa ggcggatgcc
    22921 gcgttcagtg atgggctgcc accgcaccgg cagcagttcg aggtagtcgg ccccgctcag
    22981 cgggacgggg acatagccgc tgatggtgat cagcacggcc cacatctggt tcggtgtgag
    23041 ggcggatttg ggcaggacgg ggtggcgcag tccgtcgtgg ggccggttct gccagccgca
    23101 ggtgatccat tcgtcgagga agtcctgcag ctgcgggatc gtccaccgag tctcggcctc
    23161 cgtcgctacg ccgcggcgct gggggttgga gccggtgtgg ccagcgacgt gctggcagaa
    23221 caggtcgttg atcgcaccga aggtccgctc caccacggcc ttggcctgcg gccgcctcgg
    23281 aggagcgggc tggacgctca ccccgagcgt ctcgcaggcg gcgacgaagc cctgcgagag
    23341 gtagatcttc ccgcggtcga cgacgatcgt ctcgggcacg accaccggtc gcgcggccgc
    23401 gccttccagg cgctcgtcta gcgacagcat ccgctcatag ggcacttcgg cccgagacag
    23461 atgcagcgct gagggccagg tggggcgggc aggatgcgga acagccatct cggccaggag
    23521 gagggcggcg tcgacggctt tggtgctgtg cgggcgcagg acggcggcca ggatggagcg
    23581 ggtggcgacg tcgacggcga tggtcagctc cggccggccc aggctgccgt cttcgaggac
    23641 ggtcatgatg tccaggcggg tggtgtcgat ctgcacctgc tcgccgggcc gcagcaccac
    23701 cggcgccgac gaggcgcggg cgggtgcggt ggcggttcgc gccgggcggc ctgggcgatc
    23761 ggccgggtcg gccagcacgc tcaccagccg gtagaacgtc gagcgtgaag gcatctccac
    23821 taccccgcgc ccgtgcgtgt cctccaggat ctgcccgacc acgacctgga gccccttcac
    23881 cgtccccttc gaccggcctc gctggcgccg cagcgcctcc agcaccgcgg ccacgacccg
    23941 ttcgtcggca taccccgtcg gatgacggcc acgggccggc accgtgcgtt tgtcgaccag
    24001 cccccacagg ccctgcttgc ggtagacgtg ccgcatccgc tccaccgtcg tacgcgtcac
    24061 ccgcgcgaag ccgagcgccg ccagttcctt cgccttggcc gcatcccgct gtgccagggt
    24121 ccatcgctct gggtcgtact ccggccgcat cgcctgcccc tcacggccac cctcagggtg
    24181 cggccacccg gtctccacct cccgaatatg gggcagccag gccagcgccc gctgctgggc
    24241 cgccaccgga acggtctcga acagccccca ctgcggcaca acctccggcg cccgcccgcc
    24301 caccacttcg aaacccggat cggcgaacaa ccgccccagc agcaggctca tttcagcgcc
    24361 atcctcctgc accaggtaga cctgctggcc ctgcaaggcg gcgacctgcc aggtctgtcc
    24421 ccggtaggtg atgtgtgcgc cgacctccac caccggccgt tggctcttac cgtgtgtgcc
    24481 gcccactgcg ctcacccctt ccccggcccg ccgctggcgt ccagccgctt ttcgacgccc
    24541 ccaccattac gttctgcgtc agcgcagacc agcgcctcct cctgcagcgg ctcatcaaga
    24601 ggtgtcgtca gatgcccgca ccacagcgcg tgatagacag ccggcagtac ctgcagagga
    24661 tcacccaccg cggctgtccc gtcggccagc ggccggggcc cggcgaacgc ctcactcagt
    24721 gcggcctgca gcccgggcgg gccttgattg cgtgggtggc ggtagccggc cagccatcgc
    24781 aggttcgccg ccaccaccgc tggaggtggc tcgaggcgcc gataggccca gcccacgcgg
    24841 gcacacgccg cctccaggat catccgcgcc cgctgcgccc tttccccgcc ggcggtcggg
    24901 ctggaggggc agtcggcgag caggccggtg ccgtcggcgt accgggcgaa cagctgaggc
    24961 acccacgaac gcgctcgccc gtcggccgtg tcccgccaca gcagccgtac cggacgggcg
    25021 gccaggccgg tcacgtccgg attccggtcc agcaccatca gctgggtgcg catcgctgcc
    25081 gaaccgtgta cgacgtgccg tccagtggtc gccgaccacc accagcccgg cccccaccgg
    25141 cggcccggaa cgaccggaaa cgcggatacc ggcgcgacgt cctcgaaccg caccgacgcc
    25201 gccgcctgat cccacagcaa ctgcgtcaac cgcccggcgg ccgtgacgaa cgcggcctcg
    25261 attcccgcac cgtcgccccc tgcggcagcc tgctgcaccc gcctgctgtg ctcgtgcccc
    25321 tccacactca atagccaagc ccaagtcgtg ctgccgaaag tcgcgatccg aatccgccac
    25381 ccgaacgggt gaacggcggc cgtgacgcca agctccttca cccgtggtca gaccgggaag
    25441 attcttagtt cctgcaggag ccgctgctgg ccgggcaaca gggtgtgaag ttgcgcgagc
    25501 tgctcactga tccaggagcg cagcttaggc gatggttcga ggccggcggc gagcaggaga
    25561 cgcagacggt ggtagtcgcg ctgccaggcg aacgcccacg gagggaacca ccacggatcc
    25621 agagcaacaa gggcctgcat gcctggccat ggagccggtg tgcggcgcgc gtgggctccg
    25681 gcctctccgc gtttgccggc gagccacctg cccagaggga acccgtggtg ctgaacgggg
    25741 tgcggcagcg ccaggtggcc gtgaacgccg gcgtagtccc gggcatgagc caagcccacg
    25801 gcgaagtcga tccgggcgcc ggtggggcgg taccgcgcgg tctgcctggc ttgcgctccc
    25861 tcgacggtga tgccgatctc ctgcagtaga tcttgctggc gcgggtggag ctcttcgaac
    25921 agggcacact gcgcgtacag ccatgatgcg gcagacgccc ccatcccggc gaagccatcc
    25981 cccggcacca gcggctgatg gctgccgcac tgcttgcggg cgtggtggta ggcgcgttgc
    26041 catgccaagg gccacggcgg gttccaccac gggtcgatgg ccgacagcgc acggctccgg
    26101 tcggtttcct gctccgccat acgggcccgg ctgcgttggc tcatcagcca ttgcccaaga
    26161 ggaaagccgt cctgctgcgt gctcttggac gtggcgaggt ggccgtggac ggcggcaaag
    26221 gctcgggcgt agtccagacc ggccgcgaag gcctgcgcaa ggcttt
//
