LOCUS       NZ_CP047147            22286 bp    DNA     linear   CON 30-JAN-2024
DEFINITION  Streptomyces sp. GF20 chromosome, complete genome.
ACCESSION   NZ_CP047147
VERSION     NZ_CP047147.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. GF20
  ORGANISM  Streptomyces sp. GF20
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7311137)
  AUTHORS   Li,J., Ni,J. and Li,Y.
  TITLE     Multiple polyene macrolides produced by antifungal Streptomyces from
            gut of Macrotermes barneyi facilitates the termite-fungus mutualism
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7311137)
  AUTHORS   Li,J., Ni,J. and Li,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-DEC-2019) State Key Laboratory of Microbial
            Technology, Shandong Unversity, 72 Binhai Road, Qingdao, Shandong
            266237, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 29-NOV-2019
            Assembly Method                   :: SPAdes v. Nov-2019
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/30/2024 05:38:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,372
            CDSs (total)                      :: 6,281
            Genes (coding)                    :: 6,197
            CDSs (with protein)               :: 6,197
            Genes (RNA)                       :: 91
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 50 of 84
            Pseudo Genes (internal stop)      :: 9 of 84
            Pseudo Genes (multiple problems)  :: 17 of 84
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:01:42
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5406978
            Orig. end                         :: 5429264
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP047147.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Jinfeng Ni.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22286
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="17"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22286
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22286
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12286](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12286)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            1281..2036
                     /gene="ureA"
                     /locus_tag="GR131_RS23495"
                     /old_locus_tag="GR131_23495"
     CDS             1281..2036
                     /EC_number="3.5.1.5"
                     /GO_function="GO:0009039 - urease activity [Evidence IEA]"
                     /GO_process="GO:0019627 - urea metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="ureA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018893464.1"
                     /locus_tag="GR131_RS23495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_23495"
                     /product="urease subunit gamma"
                     /protein_id="WP_037845248.1"
                     /transl_table=11
                     /translation="MRLTPTERDRLLIFNAAQLARARQARGLRLNVPEATALISDTVCE
                     AARDGARLAEAVAAGRAVLGPDDVLPGVADVLTEIQVEAVFEDGSRLAVLADPIGGGHT
                     GDQAPGALLPGPPHAEPSPVLTVAVTNTATVPVSVTSHFHFFEANPRLRFDRAAAYGMR
                     LAVPAGSSLRFGPGETREAGLVPIGGARVVTGFAGLVDGPLDAPGARAEALRRAAACGY
                     LGAEAPGTEPAPPGTTPAPPGAPTPETDV"
     gene            2033..3835
                     /locus_tag="GR131_RS23500"
                     /old_locus_tag="GR131_23500"
     CDS             2033..3835
                     /EC_number="3.5.1.5"
                     /GO_function="GO:0009039 - urease activity [Evidence IEA]"
                     /GO_process="GO:0043419 - urea catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470907.1"
                     /locus_tag="GR131_RS23500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_23500"
                     /product="urease subunit alpha"
                     /protein_id="WP_236570822.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 3.2e-46, bitscore:
                     156.7, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDPTGRALPEELTPRPRAFPHLARTPHGRRTAPDEAATASDPYA
                     YAAVHGPRAGDRVRLGDTGLTVRVGADAQRPGDEFLAGFGKTARDGLHLRAAAVRDTCD
                     LVISNVLVIDAVLGIRKVSIGVREGRIHAVGRAGNPDTLDGVDVVVGTGTTIVSGEGLI
                     ATAGAIDTHVHLLSPRVMEASLASGVTTIIGQEFGPVWGVGVNSPWALRHAFAAFDAWP
                     VNIGFLARGSSSHPAPLVEALAEGGACGFKVHEDMGAHTRALDTALRVAEEYDVQVALH
                     SDGLNECLSVEDTLQVLDGRTIHAFHIEGCGGGHVPNVLRMAGVPNVIGSSTNPTLPFG
                     RDAVAEHYGMIVSVHDLKPELPGDAAMARDRIRESTMGAEDVLHDLGAIGITSSDAQGM
                     GRAGETIRRTLQLAAKMKRERGPLDGDGEGDDNARVLRYLAKLTVNPARAHGLSHEVGS
                     LEPGKLADIVLWRPEYFGAKPQLVLKSGFPAYGVTGDPNAATDTSEPLVLGPQFGAHGA
                     AAAELSVAFVAGAAVGLGADALPTRRRRVPVRGTRNIGPADLLLNSRTGQVDVDARTGL
                     VTLDGDPVRSGPADSVSLNRLYFL"
     gene            3844..4923
                     /locus_tag="GR131_RS23505"
                     /old_locus_tag="GR131_23505"
     CDS             3844..4923
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414969.1"
                     /locus_tag="GR131_RS23505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_23505"
                     /product="agmatine deiminase family protein"
                     /protein_id="WP_159313173.1"
                     /transl_table=11
                     /translation="MPDAPAPSLRGTVPPGFRMPPEWAPHLLTWMAWPGPNPTFATEAA
                     LASAERAWAEVARTVRRFEPVTVLAGPGRAEGARALLGPGIEVVERPLDDAWMRDIGPT
                     FVTRVKDGARAALDWTFNGWGAQEWARWERDARIGGEVAALAGVPAYRTGLVNEGGGLH
                     VDGEGTVLLTETVQLDPDRNPGLTRAEVEAEIHAGLGTSRAVWLPRGLTGDYGRFGTRG
                     HVDIVAAFARPGVVVAHTQPDPAHPDHEVCEEITGVLRAAKDAAGRPLEVVEVPAPTVL
                     EVDGEWADYSYINHYLCNGGVVLGAFDDPRDAEAAALFRRLFPDRTVVPVDARPVFAAG
                     GGIHCITQQEPAPAPAGQG"
     misc_feature    complement(4983..4997)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 21.12"
                     /tool="antismash"
     gene            5029..6393
                     /locus_tag="GR131_RS23510"
                     /old_locus_tag="GR131_23510"
     CDS             5029..6393
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1074: major
                     facilitator family transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003951045.1"
                     /locus_tag="GR131_RS23510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_23510"
                     /product="MFS transporter"
                     /protein_id="WP_003951045.1"
                     /transl_table=11
                     /translation="MGRQQWKKIWVGSAGNMVEWFDWFVYASFATYFAGSFFPSGNPTA
                     QLMNTAGIFAVGFFMRPVGGWLLGRVGDRKGRKAALTLTVSLMSASAVLIAIAPTYGVA
                     GYGGAAVLLVARLLQGLSVGGEYAASATYLTEASDADRRGFASSFQYVSMTAGQLLGLG
                     LQIVLQRTMSDDTLHSWGWRIPFIIGALGAAVVFYLRRNMLETEVYAESSEDGVERADD
                     KGTMKALWQHRRQAFLVVALTMGGTVAYYTYTTYLTKYLSNSAGLPKETATLVSFCALF
                     VFMCVQPLAGMLSDRIGRRPLLITFAVGSTFLTVPIMTLLQHAGSFWPALGLSLLALLI
                     ITGYTSINACVKAELFPTGIRALGVALPYALGNALFGGTAEYVALWFKNGGTESGYYWY
                     VAGCAAVSLVVYLAMKETRDIDLNRVGAETGPPSAEAGPASPASGPAKTDAPLAS"
     gene            6671..8440
                     /gene="cimA"
                     /locus_tag="GR131_RS23515"
                     /old_locus_tag="GR131_23515"
     CDS             6671..8440
                     /EC_number="2.3.3.21"
                     /GO_function="GO:0043714 - (R)-citramalate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009097 - isoleucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cimA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470910.1"
                     /locus_tag="GR131_RS23515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_23515"
                     /product="citramalate synthase"
                     /protein_id="WP_018893461.1"
                     /sec_met_domain="HMGL-like (E-value: 3.8e-44, bitscore:
                     149.7, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSQATPEEPAERAPSAATKPQVARDVRGGDGARPAPAGTPASAA
                     SSAAADAAVERPLHIFDTTLRDGAQREGINLSVADKLTIARHLDDFGVGFIEGGWPGAN
                     PRDTEFFARAREEITFRHAQLVAFGATRRAGGSAADDLQVQALLDSGAPVVTLVAKAHD
                     RHVELALRTTLDENLEMVRDTVSHLRAQGRRVFVDCEHFFDGYAANPAYAKAVVRAASE
                     AGADVVVLCDTNGGMLPAQIQAVTATVLADTGARLGIHAQDDTGCAVANTLAAVDAGAT
                     HVQCTANGYGERVGNANLFPVVAALELKYGRTVLPEGALAEMTRISHAIAEVVNLTPST
                     HQPYVGVSAFAHKAGLHASAIKVDPDLYQHIDPELVGNRIRMLVSDMAGRASIELKGKE
                     LGIDLGDDRALVGRVVERVKERELAGYSYEAADASFELLLRDELRRGADGAGDAAPSRF
                     FRVESWRAITENRPDGIHANEATVKLWAKGERLLATAEGNGPVNALDRALRVALERIYP
                     ELAKFALRDYKVRILEGRSGTDSTTRVLISTGDGDAEWSTVGVAENVIAASWHALEDAY
                     TYGLLRAGVEPAE"
     gene            8599..9966
                     /locus_tag="GR131_RS23520"
                     /old_locus_tag="GR131_23520"
     CDS             8599..9966
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642015.1"
                     /locus_tag="GR131_RS23520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_23520"
                     /product="heme exporter protein CcmD"
                     /protein_id="WP_010642015.1"
                     /transl_table=11
                     /translation="MLGAAGATAAPAAADQGRPAAAAPVRTAPQAPAAATVSEVAKAWR
                     DGPVFVDPDVSDQLSDAQARDLSQEIQDSDKAIFVAVLPATFTDDVDRTMNDLRGDTGI
                     TGLYVLRIGDDLHVRADGSVLSQQATQNLESRFQGTTPADQQLTGLVENATQNMGGRAP
                     NSWSSQDSVSGSTWLGLGIAAVVVGGAAYTLTRRRKIRREQAQREALAKLRVVVDEDIT
                     AFGEELERLDFRPLEPGATDEMRGDYERGLDAYENAKSLMDHARKPEDVREVTKALEDG
                     RFALAVLDARRSGRELPVRRPPCFFDPRHGLSVADVTWAPPGGAPREVPVCAADQARLE
                     RGEAPDIRTVESDEGGRRPYWEAGPAYGPWAGGYFGGGILPGILVGTMLGHMMMSPAYA
                     ADYGSAEGFGDGGAGGGYEGGDVSGSDFDPGDFGGGGGFGDGGGFGGGGGDFGGGF"
     gene            complement(10001..12286)
                     /locus_tag="GR131_RS23525"
                     /old_locus_tag="GR131_23525"
     CDS             complement(10001..12286)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414954.1"
                     /locus_tag="GR131_RS23525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_23525"
                     /product="germacradienol/geosmin synthase"
                     /protein_id="WP_164837348.1"
                     /sec_met_domain="T1TS (E-value: 2.3e-81, bitscore: 272.9,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQPFVLPDFYVPYPARLNPHLEEARAHARVWADEMGMLEGSGIW
                     DLADLEAHDYALLCAYTHPDCDGPALSLVTDWYVWVFFFDDHFLELFKRTQDREGAKAY
                     LERLPAFMPMDLADGFPEPENPVEAGLADLWARTVPAMSEDWRRRFALSTENLLNESMW
                     ELSNINAGRVSNPLEYIEMRRKVGGAPWSAGLIEYAAQAEVPEAVAYSRPLRVLTDAFS
                     DGVHLRNDLFSYQREVEEEGELSNGVLVLERFLECTTQEAAEAVNDLLTSRLQQFENTA
                     LTELGPLFADKGLNPAESASVLAYVKGLQDWQSGGHEWHMRSSRYMNEGAVDGEAAPPT
                     PGGSPGALAAALLGGTLGTSALDVRAFFGRPARQRARSFSHVPYQRTGASLLPDFKLPF
                     PTRLSPALEQSRVDTVEWAHRMGLLVPQPGVPGSDVWDEEALAGYDFPLCAAGLHPEAD
                     LEELNLASQWLTWGTYGDDYYPAVFGRARNFAGAKLCTDRLRDFMPVEQPSAGPVPTSA
                     LERSLADLWVRTASAMPEKARRAFRQTIEVMLDSWVWELDNQAIGRIPDPIDYMEMRRA
                     TFGSDLTMSLCRLRHGNIVPEEVYRSGTIQAMEKAVSDYGALINDVFSYQKEVEFEGEI
                     HNAVLVTQNFFDCDYPTGLAYVDALMNARLEQFEHIVAHELPVLYEDFQLDGAARKVLD
                     GYVRQLENWLSAILTWHRGCKRYKEEDLSHHSPGVRRVIEAAPRGIGPNGLGASSLGTA
                     AARVFAGG"
     gene            complement(12366..12632)
                     /locus_tag="GR131_RS23530"
                     /old_locus_tag="GR131_23530"
     CDS             complement(12366..12632)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642012.1"
                     /locus_tag="GR131_RS23530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_23530"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_159313174.1"
                     /transl_table=11
                     /translation="MTGAPSRNEPLSWFKSSYSSDTGGNCIEVAYNWRKSSHSSDAGGA
                     CVEVAAHPTTIHVRDSKVPAGPTLDVTPAAWAAFVHATAGPLV"
     gene            complement(12629..13453)
                     /locus_tag="GR131_RS23535"
                     /old_locus_tag="GR131_23535"
     CDS             complement(12629..13453)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414952.1"
                     /locus_tag="GR131_RS23535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_23535"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_018893456.1"
                     /transl_table=11
                     /translation="MQQRKKSSKKVTSWEVLGKQLAEFRRVAGLTQGQLAERAQVGEDT
                     VSSVEQGRRRLQADLAERLDTILETKQALSTAVSTIPTHERFPLFVQDFIEHEQRAITL
                     LSYENHLIPGLLQTPEYARAVFNNSYPPIPAQEVEESAQARIDRQQILSSGKPPMMSFI
                     IEESVLQRHLGDPEAMRRQIEHLRACADLPFLSLQIMPTDTDAHAGLAGPLVLLETPEH
                     DHLAYIEGQYKGVMVEDPDEVSMFQQKYGMLRAQALTPHKTKALLDTLLGVT"
     gene            13566..13991
                     /locus_tag="GR131_RS23540"
                     /old_locus_tag="GR131_23540"
     CDS             13566..13991
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414951.1"
                     /locus_tag="GR131_RS23540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_23540"
                     /product="ATP-binding protein"
                     /protein_id="WP_159313175.1"
                     /transl_table=11
                     /translation="MKTETGLPAHCERFYRRERRSVPAARDFTAGVLDEWDARVPRDDV
                     LLCVSELATNALLHGVPPGRGFRLFVLRADDGGVRVEVHDSGDGHPATRAPGDEAESGR
                     GLLLVSALADDWGVGERNPGKIVWCSFRPVGVSCPGR"
     gene            complement(13972..14916)
                     /locus_tag="GR131_RS23545"
                     /old_locus_tag="GR131_23545"
     CDS             complement(13972..14916)
                     /NRPS_PKS="Domain: PKS_KR (18-105). E-value: 6.7e-09.
                     Score: 27.8. Matches aSDomain:
                     nrpspksdomains_GR131_RS23545_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018893454.1"
                     /locus_tag="GR131_RS23545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_23545"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_018893454.1"
                     /transl_table=11
                     /translation="MSRKPVDLTLPDLSGRRAVVTGASDGLGLGLAARLAQAGAEVVLP
                     VRNQEKGRAALEEIRRGAPGAEVSLRELDLSSLASVAALGEALRAEDRPVHLLVNNAGV
                     MTPPERRTTADGFELQFGTNHLGHFALTAHLLPLLRAGRARVTSQISVAADRNAINWED
                     PNWESSYNGMKAYSHSKIAFGLFGLELERRARAHDWGLTSNLSHPGVAPTSLLAARPEV
                     GRAKDTTGRRFIKALSARGILLGTVESAKFPALYAATAPEAGGGRLYGPSGPGHLGGPP
                     AEQKLYSRLRSIEDARRVWRLSEELTGVTFPGN"
     aSDomain        complement(14602..14862)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GR131_RS23545_PKS_KR.1"
                     /evalue="6.70E-09"
                     /label="GR131_RS23545_PKS_KR.1"
                     /locus_tag="GR131_RS23545"
                     /protein_end="105"
                     /protein_start="18"
                     /score="27.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VVTGASDGLGLGLAARLAQAGAEVVLPVRNQEKGRAALEEIRRGA
                     PGAEVSLRELDLSSLASVAALGEALRAEDRPVHLLVNNAGVM"
     CDS_motif       complement(14794..14862)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GR131_RS23545_0001"
                     /evalue="3.70E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="GR131_RS23545"
                     /protein_end="41"
                     /protein_start="18"
                     /score="10.0"
                     /tool="antismash"
                     /translation="VVTGASDGLGLGLAARLAQAGAE"
     gene            15036..15629
                     /locus_tag="GR131_RS23550"
                     /old_locus_tag="GR131_23550"
     CDS             15036..15629
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414949.1"
                     /locus_tag="GR131_RS23550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_23550"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_159313176.1"
                     /transl_table=11
                     /translation="MDKRPYHHGDLRAALLARAGETLREGGVGALSLRELARDVGVSPG
                     APRRHFASKQVLLDALALDGFERLIDSLVAARGGEARPFAERLDAMARAYVGFSLSDPA
                     LLSLMFSAKHSPEASEGLRDAARRWAEQGLALIRDGQSRGEVREGPPDRVALTVLAPLH
                     GYIGLAAGGAPLPQTPDRGLDDVIASVVRACAPK"
     gene            complement(15646..16017)
                     /locus_tag="GR131_RS23555"
                     /old_locus_tag="GR131_23555"
     CDS             complement(15646..16017)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018893452.1"
                     /locus_tag="GR131_RS23555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_23555"
                     /product="hypothetical protein"
                     /protein_id="WP_129809728.1"
                     /transl_table=11
                     /translation="MRTGLPRPRRPYERSPVIDGLPAGTLAELARLERTRNYLWPGAVS
                     EALRTWAAHVRLPRGRTWPRQQDGPCYCCPDPWESRELLDRVARALSRRGARELRRVLA
                     GHDQLWDPAPRPYRGEGPW"
     gene            16179..16721
                     /locus_tag="GR131_RS23560"
                     /old_locus_tag="GR131_23560"
     CDS             16179..16721
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642006.1"
                     /locus_tag="GR131_RS23560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_23560"
                     /product="VOC family protein"
                     /protein_id="WP_159313177.1"
                     /transl_table=11
                     /translation="MSDHTYYNAFEISPVPAPGPDAVAPEPFRGIYGMPAFMNIPTTDL
                     AASVEFWTRGLGFFELFSVPGTLVHLRRWAFQDVLLVAAESVPDQPPAMSFSFSGVLSE
                     VDSLVAACRALRPDAVEGPRDTPWNTRDVEVVTPENARIVFTAAKPFDPDTQEARNLEA
                     IGITPPGGTPGDNERHA"
     gene            16714..17526
                     /locus_tag="GR131_RS23565"
                     /old_locus_tag="GR131_23565"
     CDS             16714..17526
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642004.1"
                     /locus_tag="GR131_RS23565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_23565"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_201305774.1"
                     /transl_table=11
                     /translation="MPDTTDAEGLTVGQVSARLDVTVRALHHWDEIGLARPSLRTPAGY
                     RLYTVPDLERLHRIVVYRELGLGLDKIRAVLDDSATDVPAALRAQRAQIAARIDRLRQL
                     AAGLNRMIDAHEHGLLLTAEQQAAIFGPGWSPDGPVQARQRYGDTTQWRQYAERSASRT
                     PEEWQAVADDTAQLERALGEAMDAGVTPGSPEANHLVERHREVFASYFPLSRQMQVCLG
                     RMYESDPGFAAHHDAIRPGLATWFRQLVDAAARAHGIDPETATWEEDR"
     gene            complement(17551..18168)
                     /locus_tag="GR131_RS23570"
                     /old_locus_tag="GR131_23570"
     CDS             complement(17551..18168)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018896399.1"
                     /locus_tag="GR131_RS23570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_23570"
                     /product="SMI1/KNR4 family protein"
                     /protein_id="WP_159313179.1"
                     /transl_table=11
                     /translation="MSDDGAGQAGAEAVRAAWGRIDAWLRKWGPDSYARLAPPAEPGAV
                     AAAEAALHMRFPAELRASLGCHDGAGGEGVLPVKPPLSAAGIVRYWTRWMELTEEEREF
                     GDPEEEEGEPSWHPRWIPWAESDGDAQIIDGRDGPGFGRLGMKYHDEEGSFGDDAPSLA
                     AYLTEVADALENGRSVGGRVPYVGVSGEMWWAAAPAAPSGGR"
     gene            18354..19136
                     /locus_tag="GR131_RS23580"
                     /old_locus_tag="GR131_23580"
     CDS             18354..19136
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414944.1"
                     /locus_tag="GR131_RS23580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_23580"
                     /product="hypothetical protein"
                     /protein_id="WP_030308330.1"
                     /transl_table=11
                     /translation="MTRKTMWRTAVAGGAAAVFTGLAAVPAGAAEGGVSFSRVKVNGGK
                     PIVIGVKEEVEIPASVRMTTKLKFKGVPMVYPYRGKLGKGDELWSATGGTDPRVVDPKK
                     GVYDFDVAFYIHPRHADLKNKDAGTWKTCARISLVGGGHDVDDENLPLQVKRATRLTVN
                     ATPEPVTKGKTLTVKGTVTRANWDKRVYQGYGGRKVSLQFKPAGASSYKTVKKVTSNSK
                     GALKTTVKATESGTWRWTYYGNSTSGARSSSGDHVALR"
     gene            complement(19151..20821)
                     /gene="murJ"
                     /locus_tag="GR131_RS23585"
                     /old_locus_tag="GR131_23585"
     CDS             complement(19151..20821)
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0034204 - lipid translocation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="murJ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414943.1"
                     /locus_tag="GR131_RS23585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_23585"
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="WP_159313180.1"
                     /transl_table=11
                     /translation="MTQGADSAVRARTAEGRAKSAGGGLARSSLLMAVGTVVSRATGLI
                     RQVLQAAALGTGLLASTYNTANTVPTSLYTLLIGGALNAVLVPQLVRARATEPDGGRAY
                     EQRLVTLVVCVLGMGTALAVWAAPEIVGLYMRDTPGSHEAFELTVTFARFLLPQIFFYG
                     LFGIYGQVLNAREKFGAMMWTPVLNNVVLVAMFAAYLGLMVAPGRVEDITADQVRLLGI
                     GTTAGVALQALALVPFARAAGFRFRPRFDWRGTGLGRSVHAAKWTLLFVLANQVALTVV
                     THFANAADQELPEAGAGYTAYMYAQTIWLLPQSIVTVSLVTALLPRMSRAVAEGRVGDL
                     RADLTRGLRISGVVIVPTAFLFLALGPQIAALLFAHGAADAASVRPLGQMLQAFGPGLI
                     AFSAQYLLLRGFYAYEDTRTPFFMAAWVAGVDIALASACHLLLPARWAVVGMAGAYTLS
                     YLAGLALTARLLRRRLGGRIGTGGLGRAYGKVLCAAVPAAGLGWAAARAVSGPGSPGAA
                     GTWSTAVALASGVLSTAVAYLLLARLLKVEEVRRLPGLR"
     gene            complement(20902..21579)
                     /locus_tag="GR131_RS23590"
                     /old_locus_tag="GR131_23590"
     CDS             complement(20902..21579)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414941.1"
                     /locus_tag="GR131_RS23590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_23590"
                     /product="SMI1/KNR4 family protein"
                     /protein_id="WP_008414941.1"
                     /transl_table=11
                     /translation="MSDHGTTGTAGDEARARAVRDAWARIDAWMRAHAPDSYEVLAPPA
                     DPAAVEAAQAEMGVGFPADLLASLACHDGLRHWDNCLPLRPPEPVARIVDHWQMCVEID
                     EDNRADEDEPEPEGEEPWWHPQWIPWAQSDGDAQIIDMRPGPAQGRLGMAYHDDCGVFT
                     GGWPSLAAYLTEVADVLEKGGAVGGTWAPFLTTEGELWWSLKGETQLNGEPLVPAPAPA
                     AGT"
     gene            complement(21731..22213)
                     /locus_tag="GR131_RS23595"
                     /old_locus_tag="GR131_23595"
     CDS             complement(21731..22213)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (4-154). E-value: 4e-20.
                     Score: 64.6. Matches aSDomain:
                     nrpspksdomains_GR131_RS23595_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414939.1"
                     /locus_tag="GR131_RS23595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_23595"
                     /product="SRPBCC family protein"
                     /protein_id="WP_026048269.1"
                     /transl_table=11
                     /translation="MRSTAEVSVAAVIEAEPKAVYERVADVASMGRWSPECVRTAAGVG
                     PAPVGAEFKGTNKGPSGRSWSTRCRVMVARSGERFTFRVRFWGMPVATWDYRFRPVGDG
                     TATEVTETAVDQRNRLLWFLGSAVSGVWDRSAHNAETMRETLERLRETLEAERRAG"
     aSDomain        complement(21752..22201)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GR131_RS23595_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="4.00E-20"
                     /label="GR131_RS23595_Polyketide_cyc2.1"
                     /locus_tag="GR131_RS23595"
                     /protein_end="154"
                     /protein_start="4"
                     /score="64.6"
                     /tool="antismash"
                     /translation="AEVSVAAVIEAEPKAVYERVADVASMGRWSPECVRTAAGVGPAPV
                     GAEFKGTNKGPSGRSWSTRCRVMVARSGERFTFRVRFWGMPVATWDYRFRPVGDGTATE
                     VTETAVDQRNRLLWFLGSAVSGVWDRSAHNAETMRETLERLRETLE"
     misc_feature    22229..22245
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.96"
                     /tool="antismash"
ORIGIN
        1 ccgccgcttc caggcctccg cacgccgcct cgccatgccc gagctgcccg tggagacctt
       61 catcgaggcc tgcgacctgc tggtggcgca ggacaaggcg tgggtcccgc cgcacggcgg
      121 cgaggaatcc ctctacctgc ggcccttcat gatcgccacg gaggtcgggc tcggcgtcaa
      181 gccggccaac gagtacctct tcgtggtcat cgcctccccg gccggcgcgt acttccccgg
      241 cggcgtcaag cccgtctcga tctggctctc cgagaaccgc gtccgtgccg tccccggcgg
      301 cgtcggcgac gccaagaccg gcggcaacta cgccgcctcc ctcctcgccc aggccgaggc
      361 cgccgccgag ggctgcgacc aggtcgccta cctcgacgcg gtcgagcaca agtgggtcga
      421 ggaactgggc ggcatgaacc tctgcttcgt ctacggcgac cgcctcgtca cccccaccct
      481 caccggctcc ctcctcgccg ggatcacccg cgacaccctc ctctccctcg ccgccgacct
      541 cggctaccgg gccgaggagg gccgcgtctc catcgaccag tggcgggagg acagccgcag
      601 cggtgccctg accgaggtct tcgcctgcgg aacggccgcc gtcatcaccc ccgtcggccg
      661 ggtcaagacc gccaccgacg agtggaccca gggcaccggc gaacccggcg aggccaccct
      721 ccgcctccgc gaggccctcc tcgccctcca gacgggacgc acggaggacc gtcacgggtg
      781 gatgcacccg ctgggctgaa tctcgggggc cggcgccggc gccggggcgt gggagcgcct
      841 ggtgccggtc cgaccggtct gaccggacga gcgggacggc ccgtcgtccc cgcagcggat
      901 gcgggggcgg cgggccgttt cggtccgggt gcggcgcccg ggtcccggtc tccgggggta
      961 aggggtgccg tcgcggcgtc gggcttacgc gcgccgcgac ggggcgcgcg gcgtacgggg
     1021 cggccacggg gcgcgcgacc tgcggcttca cggggtacgg ggcgcgcgcc gtccggcctc
     1081 agacgtggcg ccgcaggtac ggggtgacgg ggcggggctg ccccttaccc gggccgtctc
     1141 tgcgggctcc gggcagccgc cccggctcaa gcgccgcccg ccccgccgcg cgccgtccat
     1201 tggaaaacct aaacccttta gatagggtga cgctccatcg ccccgcgccc gccgcccacc
     1261 cccatccctc caggaccccc atgcgcctga cccctaccga acgcgaccgc ctcctgatct
     1321 tcaacgccgc ccagctcgcc cgggcccggc aggcgcgcgg gctgcggctg aacgtcccgg
     1381 aggcgaccgc gctcatctcg gacacggtct gcgaggcggc gcgggacggg gcgcggctgg
     1441 cggaggcggt ggcggcgggg cgggccgtgc tcgggccgga cgacgtgctg ccaggcgtcg
     1501 ccgacgtgct gaccgagatc caggtcgagg cggtcttcga ggacgggtcc cggctcgccg
     1561 tgctggccga ccccatcggc ggcggccaca ccggcgacca ggcgcccggc gccctgctcc
     1621 cgggcccgcc ccacgccgag ccgagccccg tgctgaccgt ggcggtcacc aacaccgcca
     1681 cggtcccggt cagcgtcacc tcgcacttcc acttcttcga ggccaacccg cgcctgcgct
     1741 tcgaccgggc cgccgcctac ggcatgcgcc tcgccgtccc ggccggctcc tcgctccgct
     1801 tcggcccggg cgagacccgc gaggcggggc tggtgccgat cggcggggcg cgcgtcgtga
     1861 ccggtttcgc cgggctggtc gacggcccgc tggacgcccc cggcgcccgc gccgaggccc
     1921 tgcgccgcgc cgccgcctgc ggctacctcg gcgccgaagc acccgggacg gagcccgccc
     1981 cgcccggcac cacccccgcc ccgccgggcg cccccacccc ggagaccgac gtatgagcga
     2041 cccgaccggc cgggccctgc ccgaggagct gaccccgcgc ccccgcgcct tcccgcacct
     2101 ggcccgtacc ccgcacggcc gccgtaccgc gcccgacgag gcggccacgg cctccgatcc
     2161 gtacgcctac gccgccgtcc acggcccccg cgccggggac agggtgcggc tcggtgacac
     2221 ggggctgacg gtgcgggtcg gggccgacgc gcagcgaccc ggcgacgagt tcctggccgg
     2281 gttcgggaag accgcgcggg acgggctgca cctgcgggcc gccgccgtgc gcgacacctg
     2341 cgacctggtg atcagcaacg tgctcgtgat cgacgcggtg ctcggcatcc ggaaggtctc
     2401 gatcggtgtc cgggaaggcc gcatccacgc cgtggggcgc gcggggaacc cggacacgct
     2461 cgacggggtc gacgtggtgg tcggcaccgg caccacgatc gtgtcggggg aggggctgat
     2521 cgcgaccgcc ggggcgatcg acacccatgt gcacctgctc tcgccccgcg tcatggaagc
     2581 ctccctcgcc tccggcgtga ccacgatcat cggccaggag ttcggccccg tctggggcgt
     2641 cggcgtcaac tcgccgtggg ccctgcgtca cgccttcgcc gccttcgacg cctggcccgt
     2701 caacatcggt ttcctcgccc gcggttcctc ctcgcacccg gcgccgctgg tcgaggcgct
     2761 ggcggagggc ggggcgtgcg ggttcaaggt gcacgaggac atgggggcgc acacccgggc
     2821 gctggacacc gcgctgcgcg tcgccgagga gtacgacgtg caggtggccc tgcacagcga
     2881 cggcctcaac gaatgcctct ccgtcgagga caccctccag gtgctcgacg ggcgcaccat
     2941 ccacgccttc cacatcgagg gatgcggcgg cggccacgtc cccaacgtgc tgcgcatggc
     3001 gggcgtgccg aacgtcatcg gctcctccac caaccccacg ctgcccttcg gccgggacgc
     3061 cgtcgccgag cactacggca tgatcgtctc ggtccacgac ctcaagcccg agctgccggg
     3121 cgacgccgcg atggcccgcg accgcatccg cgagtcgacg atgggcgccg aggacgtctt
     3181 gcacgacctg ggcgccatcg gcatcacctc ctccgacgcg caggggatgg gccgggccgg
     3241 cgagacgatc cgccgcaccc tccagctcgc cgccaagatg aagcgcgaac gcggcccgct
     3301 cgacggcgac ggcgagggcg acgacaacgc ccgcgtcctg cgctacctcg ccaaactgac
     3361 cgtcaacccg gcccgcgcgc acggcctctc ccacgaggtc ggctcgctgg agcccggcaa
     3421 actggcggac atcgtgctgt ggcgccccga gtacttcggc gccaagcccc agctggtcct
     3481 gaagtccggc ttccccgcct acggcgtcac cggcgacccc aacgccgcca ccgacaccag
     3541 cgaaccgctc gtcctcggcc cccagttcgg cgcgcacggg gcggccgccg ccgagctgtc
     3601 cgtcgccttc gtcgcgggcg ccgccgtggg cctcggcgcc gacgccctgc ccacccgcag
     3661 gcgccgcgtc cccgtccgag gcacccggaa catcggcccc gccgacctcc tcctcaactc
     3721 ccgcaccggc caggtcgacg tggacgcccg caccggcctc gtcaccctcg acggcgaccc
     3781 ggtccgctcc ggccccgccg actccgtcag cctcaaccgc ctctacttcc tctgaggacc
     3841 gccatgcccg acgcccccgc cccgtccctg cgcggcaccg tcccgccggg cttccggatg
     3901 ccgcccgagt gggccccgca cctgctcacc tggatggcct ggcccggccc caacccgacc
     3961 ttcgccaccg aggccgcact cgcctcggcc gaacgcgcct gggccgaggt ggcccgcacc
     4021 gtgcgccgct tcgaaccggt caccgtgctc gccggacccg gccgcgccga aggcgcccgc
     4081 gcgctcctcg ggcccggcat cgaggtggtc gaacgcccgc tggacgacgc ctggatgagg
     4141 gacatcggcc ccaccttcgt cacccgcgtg aaggacggcg cccgggcagc gctcgactgg
     4201 acgttcaacg gctggggcgc gcaggagtgg gcccgctggg agcgggacgc gaggatcggc
     4261 ggcgaggtcg ccgcgctggc cggggtcccg gcgtaccgga cggggctggt caacgagggc
     4321 ggcgggctgc acgtcgacgg ggagggcacc gtgctgctca ccgagaccgt ccagctcgac
     4381 ccggaccgca accccggcct gacccgcgcc gaggtggagg ccgagatcca cgcggggctc
     4441 ggcaccagca gggcggtgtg gctgccgcgc gggctgaccg gtgactacgg gcggttcggg
     4501 acgcgcggcc acgtcgacat cgtcgcggcg ttcgcccggc ccggcgtggt cgtggcgcac
     4561 acccagcccg acccggccca ccccgaccac gaggtctgcg aggagatcac cggcgtgctg
     4621 cgcgccgcca aggacgcggc gggccgcccg ctggaggtgg tcgaggtgcc cgcgcccacc
     4681 gtgctggagg tggacgggga gtgggccgac tactcgtaca tcaatcacta cctgtgcaac
     4741 ggcggggtcg tcctcggcgc cttcgacgac ccgcgcgacg ccgaggccgc cgcgctcttc
     4801 cgccgcctct tcccggaccg caccgtcgtc cccgtcgacg cccgcccggt cttcgcggcc
     4861 ggcggcggca tccactgcat cacccagcag gaaccggcgc cggccccggc cggacagggc
     4921 tgagcggccc ggcgtccccg tccccacgaa cgcaaagcac tcaagtaatc ccgatcgttg
     4981 ccccatacac cttgtgtcgg aatggatgat tccggcagcg tgccgagcat gggacgacag
     5041 cagtggaaga aaatctgggt cggctcggcc ggcaacatgg tcgagtggtt cgactggttc
     5101 gtgtacgcga gcttcgccac gtacttcgcg ggttccttct tccccagcgg caacccgacc
     5161 gcccagctca tgaacaccgc cggcatcttc gccgtcggct tcttcatgcg gccggtcggc
     5221 ggctggctgc tcggccgggt cggtgaccgc aagggccgca aggcggcgct gaccctcacc
     5281 gtctcgctga tgtcggcctc cgccgtgctg atcgcgatcg cgccgaccta cggtgtggcc
     5341 ggctacggcg gcgccgccgt cctcctggtc gcccgcctgc tccagggcct ctcggtcggc
     5401 ggcgagtacg cggccagcgc gacctacctg accgaggcgt ccgacgccga ccggcgcggc
     5461 ttcgcctcca gcttccagta cgtctcgatg accgcgggcc agctcctcgg cctcggcctg
     5521 cagatcgtgc tccagcggac catgtcggac gacaccctgc acagctgggg ctggcgcatc
     5581 ccgttcatca tcggcgccct cggcgcggcc gtcgtcttct acctccgccg caacatgctg
     5641 gagaccgagg tctacgccga gtcctccgag gacggcgtcg agcgggccga cgacaagggc
     5701 acgatgaagg cgctgtggca gcaccggcgc caggcgttcc tggtcgtggc gctgacgatg
     5761 ggcggcaccg tcgcgtacta cacgtacacg acctacctga ccaagtacct gtcgaactcc
     5821 gccgggctgc ccaaggagac ggcgacgctc gtctcgttct gcgcgctctt cgtcttcatg
     5881 tgcgtccagc cgctcgccgg gatgctctcc gaccggatcg gccgccgccc gctgctgatc
     5941 accttcgccg tcggctcgac cttcctgacc gtgccgatca tgacgctgct ccagcacgcc
     6001 gggtcgttct ggccggcgct cggcctctcg ctcctcgcgc tgctcatcat caccggctac
     6061 acgtcgatca acgcctgcgt gaaggccgaa ctcttcccca ccggcatccg cgcgctgggc
     6121 gtcgccctgc cctacgccct cggcaacgcc ctcttcggtg gcaccgccga gtacgtcgcg
     6181 ctctggttca agaacggtgg gacggagtcg ggctactact ggtacgtggc ggggtgcgcc
     6241 gccgtctcgc tcgtcgtcta cctggcgatg aaggagaccc gggacatcga cctcaaccgg
     6301 gtcggcgccg agacgggccc gccctccgcc gaggcgggcc ccgcctcccc ggcctccggg
     6361 cccgcgaaaa cggacgcccc gctcgcatcc tgagacacct cgtggcacgg gggcctctct
     6421 gtgggagact gcccccgtgc ccacgttcgc catgattatc ggcagcaggc gcgccggtcc
     6481 gcagtgaccg ccccgcacca ccacgtgcga cgcggccacc gtgccccaga cccgcgcgca
     6541 gacctctcgc acccgcgagg ggtcttttcg tttgtcggcc ccgaccgggc cgcggcgagg
     6601 cgcacgagag gacgggggca agtggagcca agcattccgg agccactcac ccgacaggag
     6661 tcaccaccgc atgaccagcc aggccacccc cgaggaaccc gctgagcgcg ccccgtcggc
     6721 cgcgacgaaa ccgcaggtcg cacgcgacgt acggggcggc gacggggcgc gccccgcgcc
     6781 cgccggaacc cccgcctccg cggcgtcctc cgccgccgcg gacgccgccg tcgagcgccc
     6841 cctgcacatc ttcgacacca cgctccgcga cggcgcgcag cgtgagggca tcaacctcag
     6901 cgtcgccgac aagctgacca tcgcccggca cctggacgac ttcggggtgg gcttcatcga
     6961 gggcggctgg cccggcgcca acccgcgcga caccgagttc ttcgcccgcg cccgcgagga
     7021 gatcaccttc cgccacgcgc agctcgtcgc cttcggcgcc acccgccgcg cgggcggcag
     7081 cgccgccgac gacctccagg tccaggcgct cctcgactcc ggcgccccgg tcgtcaccct
     7141 ggtcgccaag gcccacgacc gccacgtcga gctggccctg cgcaccaccc tcgacgagaa
     7201 cctggagatg gtccgcgaca ccgtctccca cctgcgcgcc cagggccgcc gggtcttcgt
     7261 cgactgcgag cacttcttcg acgggtacgc cgccaacccg gcctacgcca aggccgtcgt
     7321 ccgcgccgcg agcgaggccg gcgccgacgt cgtcgtcctc tgcgacacca acggcggcat
     7381 gctgcccgcg cagatccagg ccgtcaccgc caccgtcctc gccgacaccg gcgcccgcct
     7441 cggtatccac gcccaggacg acaccggctg cgccgtcgcc aacaccctcg ccgccgtcga
     7501 cgcgggcgcc acccacgtcc agtgcaccgc caacggctac ggcgagcgcg tcggcaacgc
     7561 caacctcttc ccggtcgtcg ccgccctgga gctgaagtac ggccgcaccg tgctccccga
     7621 gggcgcgctc gccgagatga cccgcatctc gcacgccatc gccgaggtcg tcaacctcac
     7681 cccctccacc caccagccct acgtcggcgt ctccgccttc gcgcacaagg ccggactgca
     7741 cgcctccgcg atcaaggtcg accccgacct gtaccagcac atcgacccgg agctggtcgg
     7801 caaccgcatc cgcatgctcg tctccgacat ggcaggccgc gcctccatcg agctgaaggg
     7861 caaggagctg ggcatcgacc tcggcgacga ccgcgccctg gtcgggcgcg tcgtggagcg
     7921 cgtcaaggaa cgcgagctgg ccgggtactc ctacgaggcc gccgacgcct ccttcgaact
     7981 gctgctccgt gacgagctgc ggcgcggtgc cgacggcgcg ggcgacgcgg ccccgtcccg
     8041 cttcttccgc gtcgagtcgt ggcgggcgat caccgagaac cgccccgacg gcatccacgc
     8101 caacgaggcc accgtgaagc tctgggccaa gggcgaacgc ctcctcgcca ccgccgaggg
     8161 caacggcccc gtcaacgccc tggaccgcgc cctgcgcgtc gccctggagc ggatctaccc
     8221 ggagctggcc aagttcgccc tgcgggacta caaggtccgc atcctggaag gccgctccgg
     8281 caccgactcc accacccgcg tcctgatctc caccggcgac ggcgacgcgg agtggtcgac
     8341 ggtcggcgtc gccgagaacg tcatcgccgc ctcctggcac gccctggagg acgcctacac
     8401 ctacggcctg ctccgcgccg gggtcgagcc cgccgagtag gcccgaagcg cgtacgcccg
     8461 gggcggcggg gcccgtaccc gccccgccgc ccgtccgggg cgtttcgcgg cgacccgggt
     8521 tagcgtggag gtatgaggcg agccgtagtc cgccagtcca tacgccgggg cgctctcatc
     8581 gcgtccgggc ctcttctcgt gctgggcgcc gccggagcga cggccgcgcc cgccgccgcc
     8641 gaccagggca ggcccgccgc cgcggcaccc gtgcggacgg ctccgcaggc ccccgccgcc
     8701 gcgaccgtct ccgaggtcgc caaggcatgg cgcgacggcc ccgtcttcgt ggacccggac
     8761 gtctcggacc agctctccga cgcccaggcg cgcgacctct cccaggagat ccaggacagc
     8821 gacaaggcga tcttcgtcgc ggtcctcccg gcgaccttca cggacgacgt cgaccggacc
     8881 atgaacgacc tgcgcggcga caccggcatc accggcctgt acgtcctgcg catcggcgac
     8941 gacctgcacg tccgcgccga cgggtcggtc ctctcccagc aggccacgca gaacctcgaa
     9001 tcccgcttcc agggcaccac cccggccgac cagcagctca ccggcctcgt cgagaacgcc
     9061 acccagaaca tgggcggccg cgcccccaac tcctggtcct cccaggacag cgtctccggc
     9121 tcgacctggc tcggcctcgg catcgccgcc gtggtcgtgg gcggcgccgc ctacacgctg
     9181 acccggcggc gcaagatccg gcgcgagcag gcccagcggg aggcgctggc caagctgcgg
     9241 gtcgtggtgg acgaggacat caccgccttc ggcgaggagc tggagcggct cgacttccgg
     9301 cccctggaac cgggcgccac cgacgagatg cggggcgact acgagcgcgg cctcgacgcc
     9361 tacgagaacg ccaagtccct catggaccac gcgcggaagc ccgaggacgt gcgcgaggtg
     9421 accaaggcgc tggaggacgg ccggttcgcg ctcgccgtgc tcgacgcccg ccgcagcggc
     9481 cgtgagctgc cggtgcgccg tccgccgtgc ttcttcgacc cgcgccacgg cctctcggtc
     9541 gccgacgtca cctgggcccc gcccggcggc gcgccccgcg aggtgcccgt ctgcgccgcc
     9601 gaccaggccc ggctggagcg gggcgaggcc cccgacatcc gcaccgtcga gtccgacgag
     9661 ggcggccggc gcccgtactg ggaggccggc ccggcgtacg gcccctgggc gggcggctac
     9721 ttcggcggcg gcatcctccc cggcatcctc gtcggcacca tgctcggcca catgatgatg
     9781 agccccgcct acgccgccga ctacggctcg gccgaaggct tcggcgacgg cggcgcgggc
     9841 ggcggctacg agggcggcga cgtctccggc tccgacttcg accccggtga cttcggcggc
     9901 gggggcggct tcggcgacgg cggcggattc gggggcggag gcggcgactt cggcggaggc
     9961 ttctgacccc ggccgagccg cccgccccgg cccgctcccg tcaccccccg gcgaacaccc
    10021 gggcggcggc cgtgcccagc gaggaggcgc cgagcccgtt cggcccgatc ccgcgcggcg
    10081 cggcctcgat cacccgccgc acgccggggg agtggtggct caggtcctcc tccttgtacc
    10141 gcttgcagcc ccggtgccag gtcaggatgg ccgacagcca gttctccagc tgccgcacgt
    10201 acccgtcgag caccttcctg gccgccccgt ccagctggaa atcctcgtac agcacgggga
    10261 gttcgtgggc cacgatgtgt tcgaactgtt ccagccgtgc gttcatcagc gcgtccacgt
    10321 aggcgaggcc ggtcgggtag tcgcagtcga agaagttctg ggtgacgagg acggcgttgt
    10381 ggatctcgcc ctcgaactcc acttccttct ggtacgagaa gacgtcgttg atcagcgcgc
    10441 cgtagtcgga gacggccttc tccatcgcct ggatggtgcc cgagcggtac acctcctcgg
    10501 ggacgatgtt gccgtggcgc aggcggcaca ggctcatcgt caggtcggag ccgaaggtgg
    10561 cgcggcgcat ctccatgtag tcgatcgggt cggggatgcg gccgatggcc tggttgtcca
    10621 gctcccagac ccagctgtcc agcatcacct cgatggtctg ccggaacgcg cggcgggcct
    10681 tctccggcat cgcggaggcg gtccgcaccc acaggtcggc cagtgagcgt tccagcgcgc
    10741 tggtcggcac cggtcccgcc gagggctgct cgaccggcat gaagtcccgc agccggtcgg
    10801 tgcagagctt ggccccggcg aagttccggg cacggccgaa gaccgccggg tagtagtcgt
    10861 cgccgtaggt gccccaggtc agccactgcg aggcgaggtt cagttcctcc aggtcggctt
    10921 ccggatggag cccggccgcg cagagcggga agtcgtagcc ggccagcgcc tcctcgtccc
    10981 acacgtccga cccgggcacc ccgggctgcg gcacgagcag ccccatccgg tgcgcccact
    11041 cgaccgtgtc cacccgggac tgctccagcg ccggggagag ccgcgtcggg aacgggagct
    11101 tgaagtccgg cagcagcgag gcccccgtcc tctggtacgg cacgtgcgag aagctgcgcg
    11161 cccgctgccg cgccggacgc ccgaagaacg cccgcacgtc cagcgccgac gtgccaagcg
    11221 tcccgcccag cagcgccgcc gccagcgccc ccggcgaccc gcccggcgtc ggaggcgccg
    11281 cctccccgtc gaccgcgccc tcgttcatgt accggctgga gcgcatgtgc cactcgtggc
    11341 cgcccgactg ccagtcctgg agccccttca cgtacgccag caccgaggcg gactcggccg
    11401 gattcagccc cttgtcggcg aagagcggcc ccagttcggt cagcgcggtg ttctcgaact
    11461 gctggaggcg tgaggtcagc aggtcgttga cggcctcggc cgcctcctgc gtggtgcact
    11521 ccaggaaccg ttccagcacg aggacgccgt tgctcagctc gccctcctcc tcgacctccc
    11581 gctggtacga gaagaggtcg ttgcgcaggt ggacgccgtc cgagaaggcg tcggtcagca
    11641 cgcgcagggg ccgcgagtac gccaccgcct ccgggacctc ggcctgcgcc gcgtactcga
    11701 tgagccccgc cgaccagggc gcgccgccga ccttgcggcg catctcgatg tactccagcg
    11761 ggttggagac gcgccccgcg ttgatgttgg acagctccca catcgactcg ttgagcaggt
    11821 tctccgtgga gagggcgaag cggcggcgcc agtcctccga catggccggg accgtccgcg
    11881 cccagaggtc ggcaagcccc gcctccaccg gattctccgg ctccgggaac ccgtcggcca
    11941 ggtccatcgg catgaacgcc ggcagccgct ccaggtacgc cttcgcgccc tcacggtcct
    12001 gcgtccgctt gaacagctcc aggaaatggt cgtcgaagaa gaagacccac acgtaccagt
    12061 cggtcaccag cgacagcgcc ggaccgtcgc agtccggatg cgtgtacgcg cagagcaacg
    12121 cgtagtcgtg ggcctccagg tcggccaggt cccagatccc cgacccctcc agcatcccca
    12181 tctcgtccgc ccagacccgg gcatgggcgc gcgcctcttc gagatgaggg ttgagccgcg
    12241 ccggatacgg cacgtagaaa tcgggcagga caaagggctg tgtcacggtc gagccttcca
    12301 cacggtgata ccggcggccc gatcactacc cgcccgcccg acccgtcagc cggacggcgg
    12361 tgttgtcata cgagtggacc ggcggtcgcg tgtacgaacg ccgcccaggc ggcgggggtc
    12421 acgtcgaggg tgggtcccgc cgggaccttg gagtcgcgga cgtggatggt ggtggggtgg
    12481 gcggcgacct ctacgcaggc gccgcccgcg tcgctgctgt ggctggactt gcgccagttg
    12541 taggcgacct cgatgcagtt gccgcccgtg tcgctgctgt agctcgactt gaaccaggag
    12601 aggggttcgt ttcgggaagg ggcgccggtc atgtcactcc aagcagtgtg tccagcaggg
    12661 ccttcgtctt atggggtgtg agggcctgcg cccgcagcat cccatacttc tgctggaaca
    12721 tactgacctc gtccgggtcc tccaccatga cgcccttgta ctgaccttcg atgtacgcaa
    12781 ggtggtcgtg ctcgggcgtc tccagcaaca cgagagggcc cgccaaacct gcgtgagcat
    12841 cagtatcggt aggcatgatc tgcaagctca ggaagggcag atcggcacag gcgcgcaggt
    12901 gctcgatctg tcgtctcatg gcttccgggt cgcccaagtg cctttggagc acgctctcct
    12961 cgatgatgaa gctcatcatc ggaggcttgc cgctcgacag tatttgctgc ctgtcgatac
    13021 gcgcttgcgc ggattcctcc acctcttggg caggaattgg cggataggag ttgttgaata
    13081 ccgctcgcgc atactccggc gtttgcagaa gcccggggat gaggtggttc tcgtacgaga
    13141 gcagggtgat ggcccgttgc tcgtgttcga tgaagtcctg gacgaacagg gggaatcgct
    13201 cgtgcgtcgg gatcgtcgac accgctgtac tcagcgcctg ttttgtctca aggattgtgt
    13261 ccaggcgttc ggccaagtct gcctgtagcc gccgcctgcc ctgctcgacc gaggagacgg
    13321 tgtcctcgcc cacctgggcg cgctcagcca gctgcccctg ggtcagcccc gccacccgcc
    13381 ggaactcggc cagttgtttg ccgagcactt cccacgacgt gaccttcttg ctggacttct
    13441 ttcgctgctg catgcgtact ccatctcccg acgcgccccg tcgcgcaccc gacacgaccc
    13501 gtacaacgga tttgtacggg tcgacgccct gcacaaggct agtgacgttg ggtgaccgta
    13561 ggagggtgaa aaccgaaacc ggactccccg cgcactgcga gcgcttctac cgccgcgagc
    13621 gccgatccgt ccccgcagcc agggacttca ccgccggcgt gctggacgag tgggacgccc
    13681 gcgtgccccg cgacgacgtc ttgctctgcg tgagcgaact ggccaccaac gccctgctcc
    13741 acggcgtccc gccggggcgc ggcttccggc tcttcgtgct ccgggccgac gacggcggcg
    13801 tacgcgtcga ggtccacgac agcggcgacg ggcacccggc gacccgcgcc cccggcgacg
    13861 aggccgagtc cggccggggc ctgctcctcg tctccgccct cgccgacgac tggggggtgg
    13921 gggagcgcaa cccgggcaag atcgtctggt gctccttccg tcccgtgggc gtcagttgcc
    13981 cgggaaggtg acgccggtca gctcctccga caggcgccag acgcggcggg cgtcctcgat
    14041 cgagcgcagg cgggagtaga gcttctgctc ggccgggggg ccgccgaggt ggccggggcc
    14101 gctggggccg tacagcctgc cgcccccggc ctcgggcgcc gtggccgcgt acagcgcggg
    14161 gaacttcgcg ctctcgacgg tgcccaggag gatgccccgg gcggagagcg ccttgatgaa
    14221 ccgccgcccg gtggtgtcct tggcgcggcc gacctcgggg cgagcggcga ggaggctggt
    14281 cggggcgaca ccggggtgcg agaggttgct cgtgaggccc cagtcgtgcg cccgtgcgcg
    14341 ccgctccagt tcgaggccga agaggccgaa cgcgatcttg gagtggctgt acgccttcat
    14401 gccgttgtag gaggactccc agttggggtc ctcccagttg atcgcgttgc ggtcggcggc
    14461 cacgctgatc tgcgaggtga cgcgggcccg cccggcgcgc agcaggggca gcagatgggc
    14521 ggtgagggcg aagtggccga ggtggttggt gccgaactgc agctcgaagc cgtcggcggt
    14581 ggtgcggcgc tcgggcgggg tcatgacgcc cgcgttgttg acgaggaggt ggaccgggcg
    14641 gtcctccgcg cgcagggcct cgccgagcgc ggcgacggag gcgagggagg acaggtccag
    14701 ctcgcgcagc gacacctcgg ccccgggcgc tccccgccgg atctcctcca gcgccgcccg
    14761 ccccttctcc tgattgcgta cgggcaggac cacctcggct cccgcctggg cgagccgggc
    14821 cgcgagcccc agaccgaggc cgtcgctggc gccggtgacc acggcgcgcc ggccggagag
    14881 atcggggagg gtgaggtcga cgggcttgcg ggacatggtt cctccagcgg ggtgcggcgc
    14941 gctctcgggt gtccgggcac gcctcgccaa tgtatgcgat ggctacaatg tattcaacga
    15001 ctacatcagc gcgtcgccgg acttacgctg agcccatgga caagcgcccc taccaccacg
    15061 gagacctgcg cgccgccctg ctcgcccggg ccggggagac cctgcgtgag ggaggggtgg
    15121 gggccctctc gctgcgcgag ctggcccgcg acgtcggcgt gagtccgggt gctccgcgcc
    15181 ggcacttcgc ctccaagcag gtgctgctcg acgccctcgc cctcgacggc ttcgagcgcc
    15241 tcatcgactc cctggtcgcc gcgcggggcg gcgaggcgcg ccccttcgcc gaacgcctgg
    15301 acgccatggc ccgcgcctac gtcggcttct ccctctccga tccggccctg ctcagcctga
    15361 tgttctcggc caagcacagc cccgaggcgt cggaagggct ccgcgacgcc gcccgccgct
    15421 gggccgaaca ggggctcgcc ctcatccggg acggccagag ccggggcgag gtccgcgagg
    15481 gcccgccgga ccgcgtcgcc ctcaccgtcc tggcccctct gcacggctac atcggcctcg
    15541 ccgccggcgg cgccccgctc ccgcagaccc cggaccgggg cctggacgac gtgatcgcct
    15601 ccgtcgtgcg cgcgtgcgca ccgaagtgaa cggcgaggcc ccgcctcacc acgggccctc
    15661 accccggtac ggccggggcg ccgggtccca cagctggtcg tgcccggcca gtacgcgccg
    15721 cagctcgcgc gccccgcgcc gcgacagggc gcgggcgacc cggtcgagca gctcccggga
    15781 ctcccagggg tccgggcagc agtaacaggg accgtcctgc tggcggggcc aggtgcggcc
    15841 gcgcggcagc cgcacatgcg cggcccaggt gcgcagggcc tcggaaacgg ccccgggcca
    15901 gaggtagttc cgcgtgcgct ccagccgggc cagctcggcg agcgtcccgg ccggcaaccc
    15961 gtcgatgacg ggcgatctct cgtagggcct gcgcgggcgg gggagtccgg tccgcaccct
    16021 tcccggcggc ttacgcggca cgggcctttc ggtggtaggt cgtcatgcgg tcagcctggc
    16081 acgggcatgt tccggatgcg cggtcttttc cgccaggccc ggagggcgca cgcgtccggc
    16141 ttgaccctca cgtcgcgtga ggcccgaggc tggggcacat gagcgaccac acctactaca
    16201 acgcgttcga gataagcccc gtgcccgccc cggggcccga cgcggtcgcg ccggagccgt
    16261 tccgcggcat ctacggcatg cccgccttca tgaacatccc gacgaccgat ctggcggcgt
    16321 cggtggagtt ctggacgcgg gggctcggct tcttcgagct gttcagcgtc ccgggcaccc
    16381 tcgtccatct gcgccgatgg gcgttccagg acgtactcct cgtggcggcg gagagcgttc
    16441 cggaccagcc gccggcgatg agcttcagct tctccggcgt gctcagcgag gtcgactccc
    16501 tcgtcgcggc atgccgggcg ctgcgcccgg acgcggtcga ggggccgcgg gacacgccct
    16561 ggaacacccg tgacgtggaa gtcgtcaccc ccgagaacgc gcgcatcgtc ttcaccgccg
    16621 cgaagccctt cgacccggac acccaggaag cacgcaacct ggaggccatc ggcatcaccc
    16681 cgccgggcgg gaccccgggc gacaatgagc ggcatgcctg acaccacgga cgccgagggc
    16741 ctgaccgtcg gtcaggtctc ggcgcgcctg gacgtgacgg tccgggcgct ccaccactgg
    16801 gacgagatcg gcctggcccg gccctccctg cgcacgcccg ccggataccg gctctacacc
    16861 gtccccgacc tggaacgcct gcaccgcatc gtcgtctacc gcgaactcgg cctcggcctg
    16921 gacaagatcc gggccgtcct cgacgactcg gccacggacg taccggccgc tctgcgcgcg
    16981 caacgcgccc agatcgccgc ccggatcgac cgcctccggc aactcgccgc cggactcaac
    17041 cggatgatcg acgcccacga acacggcctg ctgctgaccg ccgagcaaca ggccgcgatc
    17101 ttcggccccg gatggagccc cgacgggccg gtccaggccc gtcagcgcta cggggacacg
    17161 acgcaatggc ggcagtacgc cgaacgctcc gcctcccgca ccccggagga gtggcaggcc
    17221 gtcgccgacg acaccgccca gctcgaacgc gccctcggcg aggcgatgga cgccggtgtc
    17281 acccccggca gtccggaggc gaaccacctc gtcgaacgcc accgcgaggt cttcgcgtcc
    17341 tacttccccc tctcccggca gatgcaggtc tgcctcggcc gcatgtacga gagcgacccg
    17401 ggcttcgccg cccaccacga cgccatccgc cccggcctcg ccacctggtt ccgccaactc
    17461 gtcgacgccg ccgcgagggc ccacggcatc gaccccgaaa ccgcgacctg ggaggaggac
    17521 cggtgaccgc agcggtacgg cgagcgcggc tcaccggccg ccggacgggg cggcgggagc
    17581 cgcggcccac cacatctctc cgctcacccc cacatacggc acccgcccac cgaccgaccg
    17641 cccgttctcc agcgcgtccg cgacctcggt gaggtaggcc gcgagcgacg gggcgtcgtc
    17701 gccgaaactc ccctcctcgt cgtggtactt catgccgagc cgcccgaacc ccggcccgtc
    17761 cctcccgtcg atgatctggg cgtcaccgtc actctccgcc cacggaatcc accgggggtg
    17821 ccaggacggt tccccctcct cctcctccgg gtccccgaac tcccgctcct cctcggtcag
    17881 ctccatccac ctcgtccagt accgcacgat cccggcggcc gacaacggcg gcttcaccgg
    17941 cagcaccccc tcgcccccgg ccccgtcgtg acaccccaac gaggcccgca actccgccgg
    18001 aaaccgcatg tgcagggcag cctccgccgc cgccaccgcc cccggctcgg cgggcggcgc
    18061 caggcgcgcg tacgaatccg gcccccactt ccgcaaccag gcgtcgatcc gcccccacgc
    18121 cgcccgcacc gcctcggccc cggcctgccc cgccccgtcg tcactcatac agcccatccc
    18181 accacccggc agcgacagtg cctcccgccg tcgccgccac agtgatcaaa atgtgtccct
    18241 ccccgcgcac aaccgcgcac gcccctcctc tgtcccacca tcagcggaga ggaccagact
    18301 ccggccgagg cgcctgcgcg cctgttcacg cagtggcgga gaggacgaac gcgatgacgc
    18361 ggaagacgat gtggagaacg gcggtggccg gcggggcggc ggccgtgttc acggggctgg
    18421 cggcggtgcc ggccggggcg gcggagggcg gggtctcctt cagccgggtc aaggtgaacg
    18481 gcggcaagcc gatcgtgatc ggggtgaagg aagaggtcga gatacccgcc tccgtgcgga
    18541 tgacgaccaa gctcaagttc aagggcgtcc ccatggtgta cccctaccgg gggaagctcg
    18601 ggaaggggga cgagctctgg agcgccaccg gcggcaccga ccccagggtc gtggacccca
    18661 agaagggcgt ctacgacttc gacgtggcgt tctacatcca cccgcgacac gcggacctca
    18721 agaacaagga cgccggcacc tggaagacgt gcgcccggat ctccctggtc ggcggcggcc
    18781 acgacgtgga cgacgagaac ctgccgctcc aggtcaagcg cgccacccgc ctcaccgtca
    18841 acgccacgcc ggaaccggtg accaagggca agaccctcac cgtgaagggg accgtcaccc
    18901 gggccaactg ggacaagcgc gtttatcagg gctacggggg ccgcaaggtc agcctccagt
    18961 tcaagcccgc gggcgcctcc tcgtacaaga ccgtcaagaa ggtgacgtcg aacagcaagg
    19021 gcgccctcaa gaccacggtg aaggccaccg agtccgggac atggcggtgg acctactacg
    19081 gcaactcgac ctccggagcc cggtcgtcga gcggcgacca cgtcgccctg cggtagaccg
    19141 ggcccgcccg tcatcgcaga cccggcaggc ggcgtacctc ctcgaccttg agcaggcggg
    19201 cgaggaggag gtaggcgacg gcggtggaga ggacaccgga ggccagggcc acggcggtgg
    19261 accacgtccc ggccgcaccc gggctgcccg gcccggagac cgcccgcgcg gcggcccagc
    19321 ccagtccggc cgcgggaacc gccgcgcaga ggaccttccc gtaggcgcgc cccagtcctc
    19381 cggtgccgat ccgcccgccg agcctgcggc gcagcaggcg ggcggtgagg gcgagtccgg
    19441 cgaggtagga gagggtgtac gccccggcca tgccgaccac ggcccagcgc gcgggcagca
    19501 gcagatggca ggcgctcgcc agggcgatgt cgacgcccgc gacccaggcc gccatgaaga
    19561 acggcgtacg agtgtcctcg tacgcgtaga aaccgcgcag cagcaggtac tgggcggaga
    19621 acgcgatgag gcccggcccg aacgcctgga gcatctggcc gagcgggcgg accgaggcgg
    19681 cgtccgccgc tccgtgggcg aagagcaggg ccgcgatctg cgggccgagg gcgaggaaga
    19741 ggaaggcggt cggcacgatg acgacgccgc tgatccgcag cccgcgcgtc aggtcggcgc
    19801 ggaggtcccc gacacggccc tccgcgacgg cccggctcat gcggggcagc agtgccgtca
    19861 ccagggagac ggtgacgatc gactggggca gcagccagat ggtctgcgcg tacatgtagg
    19921 cggtgtagcc cgcgccggcc tcggggagtt cctggtcggc ggcgttggcg aagtgggtga
    19981 ccacggtcag cgccacctgg ttggccagca cgaacaacag cgtccacttc gccgcgtgca
    20041 cactccggcc cagtccggtg ccccgccagt cgaaccgcgg ccggaaccgg aaccccgcgg
    20101 cccgcgcgaa cggcaccagc gccagcgcct gaagagcgac cccggccgtc gtcccgatcc
    20161 cgagcaaccg cacctgatcc gcggtgatgt cctccacccg gccgggcgcc accatcagcc
    20221 cgaggtacgc cgcgaacatc gccaccagca cgacgttgtt gagcaccggc gtccacatca
    20281 tcgccccgaa cttctcccgg gcgttgagga cttgcccgta gatgccgaag aggccgtaga
    20341 agaagatctg cggcagcagg aaccgggcga acgtcaccgt cagttcgaac gcctcatggc
    20401 tccctggcgt gtcccgcatg tacaggccga cgatctccgg cgccgcccac accgccagcg
    20461 ccgtccccat cccgagcaca cagacgacga gcgtcaccag ccgctgttcg taggcccgcc
    20521 cgccgtccgg ctccgtcgcc ctggcccgta cgagctgggg caccaggacg gcgttgagcg
    20581 cgccgccgat cagcagtgtg tagagactgg tcggcaccgt gttcgccgtg ttgtacgtac
    20641 tggccagcag ccccgtcccc agagccgccg cctgcaacac ctgccggatc agccccgtcg
    20701 cccgggacac caccgtcccc accgccatca gcagcgacga ccgggccagc ccgccaccgg
    20761 cgctcttcgc ccgcccctcc gccgtccgcg cccgtactgc cgagtccgcc ccctgtgtca
    20821 tgcgctcaac ataaacgccg cgcccggccg tgccgcgtca cctgatcgag ccggtgcggt
    20881 gagccccggc ccggcggggc gtcaggtacc ggccgcaggc gccggagccg gtaccagtgg
    20941 ctctccgttg agctgggtct cgcccttgag ggaccaccac agttcgccct cggtcgtcag
    21001 gaagggggcc cacgttccgc ccacggcccc gcccttctcc aggacgtcgg cgacctcggt
    21061 caggtatgcc gccagggacg gccagccgcc ggtgaagacg ccgcagtcgt cgtggtaggc
    21121 catgccgagg cggccctggg cggggcccgg gcgcatgtcg atgatctggg cgtcgccgtc
    21181 gctctgggcc caggggatcc actgggggtg ccaccagggc tcctcgccct cgggctccgg
    21241 ctcgtcctcg tcggcgcggt tgtcctcgtc gatctcgacg cacatctgcc agtggtcgac
    21301 gatcctggcg acgggctcgg gcgggcgcag cggcaggcag ttgtcccagt ggcgcaggcc
    21361 gtcgtggcag gcgagggagg cgaggaggtc cgccgggaaa cccaccccca tctcggcctg
    21421 ggccgcctcg accgccgccg ggtcggcggg cggcgccagc acctcgtagg agtccggggc
    21481 gtgggcgcgc atccacgcgt cgatgcgcgc ccaggcgtcc cgcaccgccc gggcgcgcgc
    21541 ttcgtccccg gcggtccccg tcgttccgtg atcgctcatg tgtccgatcc caccacacgc
    21601 caccgacaac gccggacggg ccgtcagccg cggggcgcgt gaccgtacgg gaaggaccgg
    21661 gggaggcagg cgtacgttcc gccgcccccg gacgcccgcg ggagggcgac ggccggtgcc
    21721 cgggaggggc tcagccggcc cggcgctccg cctccagcgt ctcgcgcagc cgctccaggg
    21781 tctcccgcat ggtctcggcg ttgtgcgcgc tgcggtccca gacgccgctg actgccgaac
    21841 cgaggaacca caggagccgg ttccgctggt ccacggcggt ctcggtcacc tcggtcgcgg
    21901 tgccgtcccc gaccgggcgg aagcggtagt cccaggtggc caccggcatc ccccagaacc
    21961 gcacccggaa ggtgaaccgc tcgccggagc gggccaccat cacccggcac cgcgtcgacc
    22021 agctccggcc gctcgggccc ttgttggtcc ccttgaactc ggcgcccacc ggcgcgggcc
    22081 cgacacccgc cgccgtccgc acacactccg gactccaccg ccccatggac gccacgtcgg
    22141 cgacccgctc gtagaccgcc ttcggctccg cctcgatcac ggccgccacg gagacctccg
    22201 ctgtgctcct catgtccctc aaccccctct gttgtacgac aacctgtcag caggaccacc
    22261 ccacccaacc aaagccgctc ccgccc
//
