LOCUS       NZ_CP047147            20975 bp    DNA     linear   CON 30-JAN-2024
DEFINITION  Streptomyces sp. GF20 chromosome, complete genome.
ACCESSION   NZ_CP047147
VERSION     NZ_CP047147.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. GF20
  ORGANISM  Streptomyces sp. GF20
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7311137)
  AUTHORS   Li,J., Ni,J. and Li,Y.
  TITLE     Multiple polyene macrolides produced by antifungal Streptomyces from
            gut of Macrotermes barneyi facilitates the termite-fungus mutualism
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7311137)
  AUTHORS   Li,J., Ni,J. and Li,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-DEC-2019) State Key Laboratory of Microbial
            Technology, Shandong Unversity, 72 Binhai Road, Qingdao, Shandong
            266237, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 29-NOV-2019
            Assembly Method                   :: SPAdes v. Nov-2019
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/30/2024 05:38:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,372
            CDSs (total)                      :: 6,281
            Genes (coding)                    :: 6,197
            CDSs (with protein)               :: 6,197
            Genes (RNA)                       :: 91
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 43 of 84
            Pseudo Genes (incomplete)         :: 50 of 84
            Pseudo Genes (internal stop)      :: 9 of 84
            Pseudo Genes (multiple problems)  :: 17 of 84
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:01:42
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5069989
            Orig. end                         :: 5090964
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP047147.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Jinfeng Ni.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20975
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="15"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20975
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20975
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10975](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10975
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            187..804
                     /locus_tag="GR131_RS22050"
                     /old_locus_tag="GR131_22050"
     CDS             187..804
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018893589.1"
                     /locus_tag="GR131_RS22050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_22050"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_018893589.1"
                     /transl_table=11
                     /translation="MSEVRAALLIAAEAHLARRPWSAVRMGEVAASAGVSRQTLYNEFG
                     SKEGLARALARQAADGYLAGIERALARSAADPRERLRAAADWTVAAARPGTLLRSLLTG
                     CWGDPLPAPRPARTTATAPAQRCAELPLPGPGDLLAAARDRAVAALDGAAPRTDPRELA
                     RECECVLRLALSRVVAPPVVGGAGAGRRRGRVTGPSPRAGGR"
     gene            complement(770..1093)
                     /locus_tag="GR131_RS22055"
                     /old_locus_tag="GR131_22055"
     CDS             complement(770..1093)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950752.1"
                     /locus_tag="GR131_RS22055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_22055"
                     /product="multidrug efflux SMR transporter"
                     /protein_id="WP_003950752.1"
                     /transl_table=11
                     /translation="MAWLLVVVAGLLETGFAVCLKLSHGFTRLWPTIAFAAFALGSFGL
                     LTLALKRLDVGPAYAVWTGIGAAGTATYGMIFLGDVVSVLKIVSITLVICGVIGLQLSG
                     SAQ"
     gene            complement(1221..2237)
                     /gene="rsgA"
                     /locus_tag="GR131_RS22060"
                     /old_locus_tag="GR131_22060"
     CDS             complement(1221..2237)
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rsgA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966421.1"
                     /locus_tag="GR131_RS22060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_22060"
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="WP_003950753.1"
                     /transl_table=11
                     /translation="MRRYGKNPDEDDIRVRPSRRGSRPRTHTRPKHEDAAEGMVLTVDR
                     GRITCLVEGRTVTAMKARELGRKAAVVGDRVALVGDLSGQKDTLARIVRIEERASVLRR
                     TADDDDPYERVVVANADRLAIVTALADPEPRPRMIDRCLVAAYDGGLEPVLVLTKSDLA
                     SPDSLLDTYRALGVPYVVTSREELEDGSAVERVRELLDGHVTAFVGHSGVGKTTLVNAL
                     VPEEQRRVTGHVNAVTGRGRHTTVSALALPLADAAPGSWVIDTPGVRSFGLHHVDPSRV
                     IHAFPDLEPGTEECPRGCSHDEPECALDQWVADGHADPARLNSLRRLLATRERREGD"
     misc_feature    2254..2269
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     gene            complement(2255..3607)
                     /gene="aroA"
                     /locus_tag="GR131_RS22065"
                     /old_locus_tag="GR131_22065"
     CDS             complement(2255..3607)
                     /EC_number="2.5.1.19"
                     /GO_function="GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="aroA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642411.1"
                     /locus_tag="GR131_RS22065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_22065"
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="WP_003950754.1"
                     /transl_table=11
                     /translation="MTLNPVSTPLWPAPYATGAVEATVQVPGSKSVTNRALVLAALAAE
                     PGWLRRPLRSRDTVLMAEALRTLGVGIEETVSSDSAAPGSTLAKGGEAWRIIPSGLRGP
                     ATVDVGNAGTVMRFLPPLATLADGDIRFDGDPRSYERPLHGVIDALRALGARIDDDDRG
                     SLPMTVHGTGSLDGGTVEIDASSSSQFVSALLLSAPRFNQGVEVRHIGPRLPSMPHIRM
                     TVDMLRRVGAQVDEPESGGEPNVWRVTPGALLGRDLTVEPDLSNAQPFLAAALVTGGRV
                     VVPDWPAHTTQPGDRLREIFTTMGGSCELTEAGLVFTGSGRVHGIDVDLGEVGELTPGI
                     AAVAALADGESVLRGVAHLRLHETDRLAALTKEINELGGDVTETADGLRIRPRPLHGGV
                     FHTYDDHRMATAGAILGLVVKGVEIENVATTAKTLPDFPDLWTGMLDGTGQ"
     gene            complement(3650..4372)
                     /locus_tag="GR131_RS22070"
                     /old_locus_tag="GR131_22070"
     CDS             complement(3650..4372)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950755.1"
                     /locus_tag="GR131_RS22070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_22070"
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_003950755.1"
                     /transl_table=11
                     /translation="MQSTTAAPATDLWDRVTGTQTAPEFWLVVATGVAALAVVLWGPAW
                     RTARNAITIAHEGGHGLIALVTGRTLEGIRLHSDTSGLTVSRGRPTGPGMILTALAGYT
                     APSLLGLGGAWLLASGHITLLLWVATALLLALLVMVRNAYGVLTVLITGGLFVAVSWLA
                     GSEVQALFAYAAVWFLLLGGVRPVFELQSKRRRGGAPDSDADQLARLTHAPAAIWLFLF
                     HAVALCSLIGGGGWLLGR"
     gene            4462..5334
                     /locus_tag="GR131_RS22075"
                     /old_locus_tag="GR131_22075"
     CDS             4462..5334
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0018142 - protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611243.1"
                     /locus_tag="GR131_RS22075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_22075"
                     /product="SOS response-associated peptidase"
                     /protein_id="WP_075986338.1"
                     /transl_table=11
                     /translation="MCGRYAATRSPEDLSEIFGVEKTELSEAAEGQEDGHEAGASPVPT
                     ETLVPDWNVAPTKEVPAILDRPVKGSDDPRPVRQLRMLNWGLVPSWATSPDGGARMINA
                     RAETVHEKPAYRRAFASRRCILPADGYYEWVTAPEERKLEEEGKRKRARKQPYFVTPAD
                     GSVFAMAGLYEFWRDPSLPGDHPRAWWVTCSVLTTEAETAPLGVGPAEGPRALADIHPR
                     MPLMLTPDKWDAWLDPSKTDVGEVRELLGAPPEGLMRAYPVATAVSNVRNNGPGLVSEL
                     DGPEVGTLF"
     gene            5630..6277
                     /locus_tag="GR131_RS22080"
                     /old_locus_tag="GR131_22080"
     CDS             5630..6277
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642408.1"
                     /locus_tag="GR131_RS22080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_22080"
                     /product="alpha/beta family hydrolase"
                     /protein_id="WP_128825885.1"
                     /transl_table=11
                     /translation="MPAAGERVTVATDVGEARVTWVRAEVPRVVLALGHGAGGGIEARD
                     LVALAGVLPGAGVSVALVEQPWRVAGKKVAPAPKTLDKGWEAVWGEVAGEGLPVVAGGR
                     SAGARVACRTGAELGAAGVLALSFPLHPPGKPERSRAGELLGTGVPTLVVQGGRDPFGR
                     PEEFPGGSYELAEVAYGDHGFAVPKKAPVGQEEALGVITDAVGAWIERLPVG"
     misc_feature    complement(6452..6466)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.4"
                     /tool="antismash"
     gene            6658..7332
                     /locus_tag="GR131_RS22085"
                     /old_locus_tag="GR131_22085"
     CDS             6658..7332
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973756.1"
                     /locus_tag="GR131_RS22085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_22085"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_026048295.1"
                     /transl_table=11
                     /translation="MGPVTGTDAGSQDVPEKPEETSAERTARFERDALAFLDQMYSAAL
                     RMTRNPADAEDLVQETYAKAYASFHQFREGTNLKAWLYRILTNTFINSYRKKQREPQRS
                     AAEEIEDWQLARAESHMSTGLRSAESQALDHLPDSDVKSALQAIPEEFRIAVYLADVEG
                     FAYKEIADIMGTPIGTVMSRLHRGRRQLRGMLEDYARERGLVPAGSGASAAEPNERKGA
                     GS"
     gene            7329..7637
                     /gene="rsrA"
                     /locus_tag="GR131_RS22090"
                     /old_locus_tag="GR131_22090"
     CDS             7329..7637
                     /GO_function="GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642406.1"
                     /locus_tag="GR131_RS22090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_22090"
                     /product="mycothiol system anti-sigma-R factor"
                     /protein_id="WP_003950759.1"
                     /transl_table=11
                     /translation="MSCGEPHETDCSEVLDHLYEFLDHEMPDSDSNKIRTHFDECSPCL
                     EKYGLEQAVKKLVKRCCGQDDVPADLRDKVISRLDMIRAGQAVPQHDIVPTEVADTP"
     gene            7872..8864
                     /locus_tag="GR131_RS22095"
                     /old_locus_tag="GR131_22095"
     CDS             7872..8864
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008415712.1"
                     /locus_tag="GR131_RS22095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_22095"
                     /product="hypothetical protein"
                     /protein_id="WP_008415712.1"
                     /transl_table=11
                     /translation="MRIFGKGRHRPSASWRQATDRAFTLIGDGRYEDAGALLTRAADLE
                     PWLSESWFNLALLHKFRHDWEQARTAGLRAVALLDRDTGAPDWWNVGIAATALQDWPLA
                     RRAWQAYGLKIPGDAAASGEPSGMGLGSAAVRISPEGEAEVVWGRRLDPARIEVQSIPL
                     PSSGRRWGEVILHDGVPHGERTTASGDTYPVFDEIELWAPSPVPTWVVLLEAQAPADRD
                     ALELLAADAGFAAEDWSSSVRLLCRTCSESRMPSDEGGGERHVDPHDHSEPGQPGPLGH
                     RTTSGEGDLWVPERECGIAAPPALVRGLLDGWVADSPDTRAWRDLEEVC"
     gene            8957..9613
                     /gene="def"
                     /locus_tag="GR131_RS22100"
                     /old_locus_tag="GR131_22100"
     CDS             8957..9613
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983603.1"
                     /locus_tag="GR131_RS22100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_22100"
                     /product="peptide deformylase"
                     /protein_id="WP_003950761.1"
                     /transl_table=11
                     /translation="MAQQDTEQQAVAGGVLPVDDEGFVIDTEDTEEREAAYRARGTARP
                     ITVVGNPVLHRETKDVTVFDAELAQLVDDMFASQRAAEGVGLAANQIGVDKKVFVYDCP
                     DDEGARHVGVVCNPVLDELPSERRVLDDSNEGCLSVPTAYAELARPDYAVVRGQDEKGN
                     PIVVRGTGYFARCLQHETDHLYGYLYIDRLSKRERKDALRQMAEGTPRYETVPND"
     misc_feature    complement(9705..9719)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.73"
                     /tool="antismash"
     misc_feature    9952..9965
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.14"
                     /tool="antismash"
     misc_feature    complement(9952..9965)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 21.17"
                     /tool="antismash"
     gene            10001..10975
                     /locus_tag="GR131_RS22105"
                     /old_locus_tag="GR131_22105"
     CDS             10001..10975
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470738.1"
                     /locus_tag="GR131_RS22105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_22105"
                     /product="multidrug MFS transporter"
                     /protein_id="WP_033238136.1"
                     /sec_met_domain="T1TS (E-value: 1.4e-51, bitscore: 174.8,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESRAWLLEKRLMPADKVTRYADELRYTDLIAGYYVGAPKDVISA
                     ISDFSTWFFVWDDQHDRDAVHGRRTAWYRLSAELHTALDAPGDHLAHPEPLVAAFAETV
                     HRLNGFLGPAWNERFARHFHAIVGAYDQEFENRVTKVTPKVAEYIELRRHTFGHSVWID
                     LLEPTAGREIPADLRTSGPFLAAARHCQDFSAWYNDLCSLPKELAGDDQHNLGISLIRH
                     EGLSLEEAVVEVRKRVENCVTEFEVAEKELRELLAGHLAALPGGAGTAEARSVAEAVGS
                     AVFNMRNWFSSVYWFHHESGRYRVDSWDDRSTPPYVSDLAGDA"
     gene            10972..12339
                     /locus_tag="GR131_RS22110"
                     /old_locus_tag="GR131_22110"
     CDS             10972..12339
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950763.1"
                     /locus_tag="GR131_RS22110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_22110"
                     /product="cytochrome P450"
                     /protein_id="WP_129818047.1"
                     /sec_met_domain="p450 (E-value: 6e-78, bitscore: 261.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAESTTERPATPGPRTPPLVAGSVPVLGHAPSLVRDPLAFLTGL
                     RDHGDLVRVKLGPKTAYAVCAPELVGALLRNSQEFQVGGPLWENLEVLLGKGVATSNGA
                     DHRRQRRMMQPAFRPERIASYATVMEEEARAMADRWRDGQVVDIGAETFSCAVRVVARS
                     LLEVDSIGAKADRISASLHTVFSGLYRRMILSFGPLHRLPTPANRRFERALADLHHLVD
                     EVIAERHAQGKGADDLLDILLTSEDGEGRPLGDQEIHDHLVSLIVAGAENVASTLAWCF
                     QLLTEHPAEEQRVAEEALSVAPDRPVNFGDLGSLDHTRNVIVESMRIRPAAWIFTRRAV
                     ADTELGGYRIPAGADIIYSAYAMQHDPRSFDRPDVFDPDRWIPERAEKVPQYAMMPFST
                     GNRKCPGDHFSMVEATLMLATVLPRWRLVPVPETDPAPRIGITLQPKRAVFRVESR"
     gene            complement(12426..13478)
                     /locus_tag="GR131_RS22115"
                     /old_locus_tag="GR131_22115"
     CDS             complement(12426..13478)
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521028.1"
                     /locus_tag="GR131_RS22115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_22115"
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_003950764.1"
                     /transl_table=11
                     /translation="MTTPDTTPAANAHTVGAAKNLLDPGFELTLRPMRYPDFYERYRDA
                     IKNTWTVEEVDLHSDVADLAKLSPGEQHLIGRLVAFFATGDSIVANNLVLTLYKHINSP
                     EARLYLSRQLFEEAVHVQFYLTLLDTYLPDPADRADAFAAVENIPSIREKAEFCFRWMD
                     SVDKLDQLESQADRRKFLLNLICFAACIEGLFFYGAFAYVYWFRSRGLLHGLATGTNWV
                     FRDETMHMSFAFDVVDTVRKEEPELFDDKLQEQVVAMLKEAVEAELQFARDLCGDGLPG
                     MNTESMREYLECVADQRLTRLGFAPVYGSQNPFSFMELQGVQELTNFFERRVSAYQVAV
                     EGTVSFDDDF"
     gene            complement(13478..15853)
                     /locus_tag="GR131_RS22120"
                     /old_locus_tag="GR131_22120"
     CDS             complement(13478..15853)
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966408.1"
                     /locus_tag="GR131_RS22120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_22120"
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="WP_030765450.1"
                     /transl_table=11
                     /translation="MTIAPADPSTAEVRAEEIQGPGGALLRTLTDLTADLPDTDPGRVA
                     AAALRGRNAASDEAELRSLATEAAAGLISEDPAYSRLAARLLTRTIAEEAAGQGVTTFT
                     ESVATGHREGLIADRTAAFVTAHAERLDALVDPAADDRFGYFGLRTVHSRYLLRHPHTR
                     QVIETPQHFMLRVACGLAEDDSVRALDEVASLYRLMSALSYLPSSPTLFNSGTRHPQMS
                     SCYLLDSPKDELESIYDRYHQVARLSKHAGGIGLAYSRIRARGSLIRGTNGHSNGIVPF
                     LNTLDASVAAVNQGGRRKGAAAVYLETWHADVEEFLELRDNTGEEARRTHNLNLAHWIP
                     DEFMRRVDADADWSLFSPSDVPELTDLWGDAFDAAYRAAEARGLARRTIPARELYGRMM
                     RTLAQTGNGWMTFKDASNRTANQTALPGHTVHSSNLCTEILEVTDDGETAVCNLGSVNL
                     GAFVDGGAIDWERLDEAVRTAVVFLDRVVDINFYPTEQAERSNSRWRPVGLGAMGLQDV
                     FFQLRLPFDSPEAQRLSTRIAERIMLTAYETSCDLAEKNGPLPNWDRTRTAQGVLHPDH
                     YDTDLAWPERWEALRARVAESGMRNALLLAIAPTATIASIAGVYECIEPQVSNLFKRET
                     LSGEFLQVNSYLVEDLKRLGVWDARTREALREASGSVQGFAWIPEELRALYRTAWELPQ
                     RGLIDMAAARTPFLDQSQSLNLFMETPTIGKLSSMYAYAWKKGLKTTYYLRSRPATRIA
                     RAAGGSAPATATVPAQAAPDAEAIACSLENPESCEACQ"
     regulatory      complement(16015..16091)
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(16106..16119)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.46"
                     /tool="antismash"
     misc_feature    complement(16113..16127)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 24.21"
                     /tool="antismash"
     misc_feature    complement(16144..16158)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 23.01"
                     /tool="antismash"
     gene            complement(16483..16725)
                     /locus_tag="GR131_RS22125"
                     /old_locus_tag="GR131_22125"
     CDS             complement(16483..16725)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642403.1"
                     /locus_tag="GR131_RS22125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_22125"
                     /product="YbdD/YjiX family protein"
                     /protein_id="WP_003950767.1"
                     /transl_table=11
                     /translation="MSGEAAHHPGRLGVLAHRVRAGVRWIGWYVREVSGETAYEKYAAH
                     VRRHDPDAEVMTRRQFERSRMDAREADPRDGFRCC"
     gene            complement(16722..18944)
                     /locus_tag="GR131_RS22130"
                     /old_locus_tag="GR131_22130"
     CDS             complement(16722..18944)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0009267 - cellular response to starvation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1185: carbon
                     starvation protein A"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642402.1"
                     /locus_tag="GR131_RS22130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_22130"
                     /product="carbon starvation CstA family protein"
                     /protein_id="WP_008415722.1"
                     /transl_table=11
                     /translation="MAEPAPPASGNRKLSAKSIAVWSLVAVVGAIAWSVLALSRGEEIS
                     AIWMLAAALGSYAIAYRFYSRFIANKVLKVDKNRATPAERLDNGVDFQPTDRRVLFGHH
                     FAAIAGAGPLVGPILAAQMGYLPGTIWIVAGVIFAGAVQDMVTLFFSTRRNGRSLGQMA
                     RDEIGPVGGVAALIAVFMIMIILLAVLALVIVNALAGSPWGVFSIGMTIPIALFMGVYL
                     RTLRPGKVTEVSVLGVALLLLAIVGGGWVAESSMADFFTLEPGTLVIWMVVYGFFASVL
                     PVWMLLAPRDYLSTFMKVGTIVLMAVCVIIAMPTLKMDGVTSFATSGAGPVFSGSLFPF
                     VFITIACGALSGFHSLVSSGTTPKMVQKETQIRMIGYGAMLTESFVAIMAMIAACIIDP
                     GLYFAINSPAGVLGDTVQSASEAVANLGFTISPDQLAQAAKDVEEASLLSRTGGAPTFA
                     LGMAEIFAAALGGAGMKAFWYHFAIMFEALFILTTVDAGTRVGRFMLQDTLGNVWKPMR
                     RVSWWPGVWLTSAIVVGCWGYFLWVGVHDPLGGINQLFPLFGIANQLLAAVALAVCTTL
                     LIKSGRLKWAWVTGIPLAWDVAVTLTASWQKVFSDNPAIGFFAQRAKYQDGIDAGEVLA
                     PAKSMSDMHTVVTNSTVDGVLSIVFAVLIIIVLVDAGRVSYNAIRKPESVKLAEAPFEQ
                     SKIVAPAGMFATSEEKAELALVGAGAPASAGDGDGDAPAKQGGGQA"
     gene            complement(19445..20233)
                     /locus_tag="GR131_RS22135"
                     /old_locus_tag="GR131_22135"
     CDS             complement(19445..20233)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950769.1"
                     /locus_tag="GR131_RS22135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GR131_22135"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_003950769.1"
                     /transl_table=11
                     /translation="MTTDAGGTRTRTADEPATEPTSPVRATRVPKYYRLKRHLLDMTRT
                     LPPGTSVPPERTLAAEFDTSRTTVRQALQELVVEGRLERIQGKGTFVAKPKVSQALQLT
                     SYTEDMRAQGLEPTSQLLEVGYITADDSLASLLDITAGGRVLRIERLRLASGEPMAIET
                     THLSAKRFPALRRSLVKYTSLYTALYEVYGVRPAEAEETIETSLATPREAALLATDVGL
                     PMLMLSRHSRDESGAPVEWVRSVYRGDRYKFLARLKRPVE"
     misc_feature    complement(20391..20406)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.28"
                     /tool="antismash"
     misc_feature    complement(20416..20431)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: strong, score: 24.29"
                     /tool="antismash"
ORIGIN
        1 caagcacatg ggcgagacgc agatcatcgt gatagtcggc catgggcgaa acagtatcga
       61 tctccggccg cgccgggcca tccggtcacc ggcgggcgcg gcgcccccac ctcgcgcgca
      121 cacccccttg acaccacccg cgcccgcgca agacttcccc gcacgaccct cgccggggag
      181 gcagccgtgt cggaagtccg cgcagccctg ctcatcgccg ccgaggccca cctggcccgc
      241 cgcccgtgga gcgcggtgcg gatgggcgag gtggcggcct cggccggggt ctcccggcag
      301 acgctctaca acgagttcgg cagcaaggaa gggctcgccc gcgccctggc ccggcaggcg
      361 gccgacggct acctcgccgg gatcgaacgg gccctggccc gctccgcggc cgacccccgc
      421 gagcggctgc gcgccgccgc cgactggacc gtggccgccg cccgccccgg caccctgctg
      481 cgctccctgc tgaccggctg ctggggcgac ccgctgcccg caccgcgccc ggcccgcact
      541 accgccaccg cgcccgccca gcgctgcgcc gaactcccgc tccccggccc cggggacctc
      601 ctcgccgccg cccgcgaccg cgccgtggcc gccctcgacg gggcggcgcc ccggaccgac
      661 ccgcgcgaac tggcccgcga gtgcgaatgc gtgctgcgcc tggccctctc ccgggtcgtg
      721 gcgccgccgg tggtgggggg tgcgggggcg gggcggcggc gcgggcgggt cactgggccg
      781 agcccgagag ctggaggccg atgacgccgc agatgacgag ggtgatggag acgatcttca
      841 gaaccgagac cacgtcgccg aggaagatca tgccgtaggt ggcggtgccg gcggcgccga
      901 tgccggtcca caccgcgtag gccgggccga cgtccaggcg cttgagggcg agggtcagca
      961 ggccgaagct gccgagggcg aacgcggcga aggcgatcgt cggccacagc cgggtgaacc
     1021 cgtgcgacag cttgagacag acggcgaacc ccgtctccag cagccccgcg acgacgacca
     1081 gcagccatgc catgaatgag cctttccgcc cgccgaaacg atcccgcgcg caccttgtag
     1141 ggcttcgggc gattatgccc gtgccgtccg gtgcggcagg cgacccggcc cggcccgtcg
     1201 cgccgcaggc cgcgcccgga tcagtcgccc tcgcgccgct cccgggtcgc cagcagccgc
     1261 cgcagcgagt tgaggcgggc cgggtcggcg tggccgtcgg ccacccactg gtcgagcgcg
     1321 cactccggct cgtcgtggct gcacccgcgc gggcactcct ccgtccccgg ctccaggtcg
     1381 gggaaggcgt ggatcacgcg ggaggggtcg acgtggtgca gcccgaacga gcgcaccccc
     1441 ggcgtgtcga tcacccagct gccgggggcg gcgtcggcca gcggcagcgc cagcgcggag
     1501 accgtggtgt gccggccgcg gccggtgacc gcgttgacgt ggccggtgac ccgtcgctgc
     1561 tcctcgggga ccagagcgtt caccagcgtc gtctttccga cacccgaatg gcccacgaag
     1621 gcggtgacat ggccgtccag cagctcccgg acccgctcca cggccgagcc gtcctccagc
     1681 tcctcccggc tggtcaccac gtacggcacg cccagcgccc ggtaggtgtc cagcagggag
     1741 tcgggggagg ccaggtccga cttggtcagc accaggaccg gctccaggcc gccgtcgtac
     1801 gcggcgacca ggcagcggtc gatcatccgg ggccggggct ccggatcggc cagcgccgtg
     1861 acgatcgcca gccggtcggc gttggcgacg accacccgct cgtacgggtc gtcgtcgtcg
     1921 gccgtgcggc gcagcaccga ggcgcgctcc tcgatccgca cgatgcgcgc cagggtgtcc
     1981 ttctgcccgg agagatcccc gaccagcgcc acccggtcgc ccaccaccgc cgccttgcgg
     2041 cccagttcgc gggccttcat cgcggtcacc gtgcggccct cgaccaggca ggtgatccgg
     2101 ccccggtcca ccgtgagcac cattccctcg gcggcgtcct cgtgcttggg gcgggtgtgg
     2161 gtgcgggggc ggctgccccg gcggctgggg cggacgcgga tgtcgtcctc gtcggggttc
     2221 tttccgtaac ggcgcatcgt tcagctcccg gccgtcactg cccggtcccg tcgagcatgc
     2281 cggtccacag gtcggggaag tcgggcaggg tcttcgcggt ggtggcgacg ttctcgatct
     2341 cgacgccctt caccaccagg cccaggatcg caccggcggt cgccatccgg tggtcgtcgt
     2401 aggtgtggaa gacgccgccg tgcagcgggc ggggccggat gcgcaggccg tcggcggtct
     2461 cggtgacgtc gccgcccagc tcgttgatct ccttggtgag cgcggccagc cggtccgtct
     2521 cgtggagccg caggtgggcg acgccgcgca ggaccgactc gccgtcggcc agggccgcga
     2581 cggcggcgat gcccggggtc agctcgccga cctcgcccag gtccacgtcg atgccgtgga
     2641 cgcggcccga gccggtgaag accaggcccg cctcggtcag ctcgcaggaa ccacccatcg
     2701 tggtgaagat ctcccgcagc cggtcacccg gctgcgtggt gtgggccggc cagtccggaa
     2761 cgaccacacg gccgccggtg accagcgccg ccgccaggaa gggctgggcg ttggacaggt
     2821 ccggctcgac ggtgaggtcc cggccgagca gggcgcccgg ggtgacccgc cagacgttgg
     2881 gctcgccgcc ggactccggc tcgtccacct gggcgccgac ccggcgcagc atgtcgacgg
     2941 tcatccggat gtgcggcatc gagggcagcc gcggaccgat gtgccggacc tcgacgccct
     3001 ggttgaaccg gggcgccgac agcagcaggg cactgacgaa ctgggaggac gaggaggcgt
     3061 cgatctccac cgtgccgccg tcgagggagc ccgtgccgtg caccgtcatc ggcaggctgc
     3121 cccggtcgtc gtcgtcgatc cgggcgccca gcgcgcgcag cgcgtcgatc acgccgtgca
     3181 gcggacgctc gtaggagcgc gggtcgccgt cgaagcggat gtcgccgtcg gcgagggtgg
     3241 cgagcggcgg caggaagcgc atcacggtgc ccgcgttgcc gacgtcgacg gtggcggggc
     3301 cgcgcaggcc ggacgggatg atccgccacg cctcgccgcc cttggccagg gtgctgcccg
     3361 gtgcggccga gtcggacgag acggtctcct cgatgcccac gccgagggtg cgcagcgcct
     3421 ccgccatcag cacggtgtcg cgggagcgga gcggccggcg cagccagccc ggctcggcgg
     3481 cgagcgccgc cagcaccagc gcgcggttgg tgaccgactt ggaccccggt acctggaccg
     3541 tcgcctcgac ggctccggtc gcgtacgggg caggccagag gggggtggat acggggttca
     3601 gggtcatgcc gtcactttag tgcgcccagc cgctcctccc cgtgcacggt caccggccga
     3661 gcagccagcc gcccccgccg atcagcgagc agagcgccac cgcgtggaag aggaagagcc
     3721 agatggccgc cggggcgtgg gtcagccggg cgagctggtc ggcgtcggag tccggggcgc
     3781 cgccgcgccg ccgcttcgac tggagctcga agaccgggcg taccccgccc agcagcagga
     3841 accagacggc cgcgtaggcg aagagggcct gcacctcgga gccggccagc caggagaccg
     3901 ccacgaagag gccgccggtg atcagcaccg tcagcacgcc gtaggcgttg cggaccatca
     3961 cgaggagggc gagcagcagg gccgtcgcca cccacagcag cagggtgatg tgcccggagg
     4021 ccagcagcca ggcgccgccg aggccgagga gggagggggc ggtgtaaccg gcgagggcgg
     4081 tgaggatcat gcccgggccg gtgggcctgc cccggctcac ggtcagcccg gaggtgtccg
     4141 agtggaggcg tatcccctcc agggtgcggc cggtgaccag ggctatcagg ccgtggccgc
     4201 cctcgtgggc gatggtgatc gcgttccgcg cggtgcgcca ggccgggccc cacaggacca
     4261 cggcgagcgc cgccacgccg gtcgccacga ccagccagaa ctcgggggcg gtctgggtcc
     4321 cggtgacgcg gtcccacagg tcggtggccg gggcggcggt ggtgctctgc atactcgggc
     4381 ggctcctcgc gagggtggga cgcgcggccc cgggccccaa ctggtggcgg tccggtggca
     4441 cggcctggca gtctggcacg tatgtgcgga cggtacgcgg ccacccggag ccccgaggac
     4501 ctcagcgaga tcttcggcgt cgagaagacc gagctgagcg aggcggcgga aggccaggag
     4561 gacggccacg aggcgggggc gtcccccgtg cccaccgaga ccctcgtccc cgactggaac
     4621 gtggcgccca ccaaggaggt tcccgccatc ctcgaccggc cggtcaaggg gagcgacgac
     4681 ccgcgccccg tacggcagtt gcggatgctg aactgggggc tcgtcccctc ctgggccacc
     4741 tcgcccgacg gcggcgcccg catgatcaac gcccgggccg agaccgtcca cgagaagccc
     4801 gcctaccgcc gggccttcgc ctcgcggcgc tgcatcctcc ccgccgacgg ctattacgag
     4861 tgggtgaccg ccccggagga gcggaagctg gaggaggagg ggaagcggaa gcgggcccgt
     4921 aagcagccct acttcgtgac gcctgccgac gggtcggtct tcgcgatggc cgggctctac
     4981 gagttctggc gtgatccctc gttgccgggg gaccatccgc gggcctggtg ggtgacgtgt
     5041 tccgtcctca ccaccgaggc ggagacggcg ccgctcgggg tggggcccgc ggaggggccc
     5101 cgggcgctgg ccgacattca tccccggatg ccgttgatgc tgacgccgga caagtgggac
     5161 gcgtggcttg atccgtcgaa gacggatgtg ggggaggtgc gggagttgct gggggcgccg
     5221 cctgaggggt tgatgcgggc ctatcccgtg gccacggcgg tgagcaatgt gcggaacaac
     5281 gggcccgggc tcgtgtccga gctggacggg cccgaggtgg ggacgctgtt ctagcgtgcg
     5341 ggggcctcaa gcgccggccg ggctgatcag gggtgtgctg tgcgtggcga ccgtgccggt
     5401 cacagatggc ctcaaacgcc ggccgggctt gaaaggtggc ctcaaacgcc ggccgggcta
     5461 ggttttgccg gtcgggctgg gttttgccgg tcgggccggg ttttggcggt cgggcttggg
     5521 ggtgtgctgg ctggggcgtc gccggtggtg ccggaggggc ggggtgtggt cggcggggca
     5581 ggatggcggg atgaacgtag cgaggtctga gggtgtggct gttcccgctg tgccggcggc
     5641 gggggagcga gtgacggttg ccacggatgt gggggaggcg cgggtcacct gggtgcgggc
     5701 ggaggtgccg cgcgtcgtgc tggcgctcgg gcacggggcc gggggtggga tcgaggcgcg
     5761 ggatctggtg gcgttggcgg gggtgttgcc gggggccggg gtgagtgtgg ccttggtgga
     5821 gcagccctgg cgggtggcgg ggaagaaggt ggcgccggcg ccgaagacgc tggacaaggg
     5881 gtgggaggcg gtctggggcg aggtggccgg ggaggggctg ccggtggtgg cgggcgggcg
     5941 cagcgcgggg gcgcgggtgg cctgccggac cggggcggag ctgggggccg ccggggtgct
     6001 cgcgctgagc tttccgctgc atccgccggg gaagccggag cggagccggg ccggggaact
     6061 gctcgggacg ggggtgccga cgctggtggt gcagggcggg cgggacccgt tcgggcggcc
     6121 ggaggagttc cccgggggga gctacgagct ggccgaggtg gcgtacggcg atcacgggtt
     6181 cgccgtgccg aagaaggcgc ccgtcggcca ggaggaggcg ctcggggtga tcacggacgc
     6241 ggtgggggcg tggatcgaac ggctgccggt gggctgaggc ggggcatggg gtggccggag
     6301 gcccccgggc gtcgcggtgg ggcgggcggg cctcgcgtcg gtcggggcgg gctcgcgtcg
     6361 gacggcagcg ggcctcgtgg tggaggcggt gggcctcgtg gggggccggg aatgccgagc
     6421 gggcggcggc tgttgtgcgg ggcgaaggtg cttcgccagc gttgatcacg agaggaagtc
     6481 cgccgcatgg gttcgaccat ctgcccgagc cgcgagcgcg ccaccgacct ggagtggtcg
     6541 gtgctgcagg cgcccgtgcg cactggctcc ggccgggatc gccgggaagt ccaggagcgt
     6601 ggtctatcct ccgattcggg cggtccggcc ggcgggcccg ccacaacgct gaaggaggtg
     6661 ggtccggtca cggggaccga cgcgggaagc caggatgtgc ccgagaagcc cgaggagacc
     6721 tcggcggagc ggaccgcgcg gttcgagcgg gacgcgctcg ccttcctcga ccagatgtac
     6781 tcggcggccc tgcggatgac ccgcaacccg gccgacgccg aggacctggt ccaggagacc
     6841 tacgccaagg cgtacgcgtc gttccaccag ttccgtgagg gcaccaacct caaggcatgg
     6901 ctctaccgga ttctcaccaa caccttcatc aactcgtacc gcaagaagca gcgtgagccc
     6961 cagcgcagcg ccgccgagga gatcgaggac tggcagctgg cgcgtgccga gtcgcacatg
     7021 tcgaccggtc tgcgctccgc cgagtcccag gcgctggacc accttcccga ctccgacgtg
     7081 aagtccgccc tccaggcgat ccccgaggag ttccgcatcg ccgtctatct ggccgatgtc
     7141 gaggggtttg cctacaagga gatcgcggac atcatgggta cacccatcgg gacggtgatg
     7201 tcccgcctgc accgcggccg ccgccagctg cgcggcatgc tggaggacta cgcccgcgag
     7261 cgcggactgg tccccgccgg ttccggggcg agcgcggcgg aaccgaacga gcggaaaggc
     7321 gcggggtcat gagctgcgga gagccgcacg agacggattg cagtgaagtc ctggaccatc
     7381 tctacgagtt cctcgaccac gagatgcccg acagcgactc caacaagatc cgcacgcact
     7441 tcgacgagtg ctctccctgc ctggagaagt acggcctgga gcaggccgtc aagaagctgg
     7501 tcaagcggtg ctgcggtcag gacgacgtcc ccgcggacct tcgggacaag gtgatcagcc
     7561 gcctggacat gatccgggcg ggccaggcgg tcccgcagca cgacatcgtc ccgacggaag
     7621 tggcggacac gccctgacct ccgggacggc ccgggagcgg gcggatacag gccggacgct
     7681 cccggggcaa gtcactcgat agagcgaccc ggtccgagaa ggtctgcacc tcacgccagt
     7741 gggtaaccca tgggtaatga gcgacgcccc aaccgtccgt ggttggatgc gaagaggtac
     7801 cccgtcccca ggctcagcgc cgtcgcacgg gcgggggacc cgaagggacc ggacaccggc
     7861 aggcgggaat cgtgaggatc ttcggcaagg gacggcaccg cccctccgcc tcctggcggc
     7921 aggcgaccga ccgagcgttc accttgatcg gcgacggccg gtacgaggac gcgggcgcgc
     7981 tgctcacgcg cgccgccgac ctggagccgt ggctctccga gtcctggttc aacctcgccc
     8041 tgctccacaa gttccgccac gactgggaac aggcccgtac cgcgggcctg cgcgccgtcg
     8101 ccctgctgga ccgggacacc ggcgcccccg actggtggaa cgtcggcatc gccgccaccg
     8161 ccctccagga ctggccgctg gcccgccgcg cctggcaggc gtacggactg aagatccccg
     8221 gggacgcggc ggcctccggt gagccgtccg ggatggggct gggcagcgcc gccgtgcgga
     8281 tctcccccga gggggaggcc gaggtggtct ggggccggcg gttggacccg gcccgcatcg
     8341 aggtgcagtc gatcccgctg ccctcctccg gccgccgctg gggcgaggtg atcctgcacg
     8401 acggggtccc gcacggcgag cggaccaccg cttcgggtga cacctatccg gtcttcgacg
     8461 agatcgagct gtgggcgccc tccccggtgc cgacctgggt ggtgctgctg gaggcgcagg
     8521 ccccggccga ccgggacgcc ctggagctgc tggccgccga cgccgggttc gccgccgagg
     8581 actggtcctc gtccgtacgg ctgctctgcc ggacctgttc ggagagccgg atgcccagcg
     8641 acgagggcgg cggcgagcgg cacgtcgacc cgcacgacca cagcgaaccg ggccagcccg
     8701 gaccgctggg ccaccggacc acctccggcg agggcgacct gtgggtcccc gagcgcgagt
     8761 gcggcatcgc cgccccgccc gccctggtgc gcggcctgct cgacggctgg gtcgccgaca
     8821 gcccggacac ccgcgcctgg cgcgacctcg aagaggtgtg ctgagccgct ccgtcctcgc
     8881 ggccacccgc gccgccgccc ccgcgtaggc tgtacgggca cggacaacgg gttcccagga
     8941 aggcgcggaa gcggacatgg cgcagcagga cacggagcag caggcggtgg cgggcggtgt
     9001 gctgccggtc gacgacgagg ggttcgtcat cgacaccgag gacaccgagg agcgtgaggc
     9061 ggcctaccgc gcccggggca ccgcgcgtcc gatcaccgtg gtgggcaacc cggtgctgca
     9121 ccgcgagacg aaggacgtca cggtcttcga cgcggagctg gcccagctgg tggacgacat
     9181 gttcgccagc cagcgggcgg cggagggcgt gggcctggcc gccaaccaga tcggcgtgga
     9241 caagaaggtc ttcgtctacg actgcccgga cgacgagggc gcgcgccacg tcggcgtggt
     9301 ctgcaacccg gtcctggacg agctgccctc cgagcgccgc gtcctcgacg actccaacga
     9361 ggggtgcctc tcggtcccca ccgcctacgc ggagctggcc cgccccgact acgcggtggt
     9421 ccgcggccag gacgagaagg gcaacccgat cgtggtgcgc ggcaccggct acttcgcccg
     9481 ctgcctccag cacgagacgg accacctgta cggctacctc tacatcgacc ggctctccaa
     9541 gcgcgagcgc aaggacgccc tgcggcagat ggccgagggc accccgcgct acgagacggt
     9601 ccccaacgac tgaggcaccc ccgccggccc gccgccgcgg acccgcaccg ccccgctctc
     9661 cccgtacggg aggcggggcg gtggtgtgtc gtggggacat gatcaatttt cggacacgta
     9721 tggcgatctt cgggtcggcg cggggtggcg aatggagcaa atctgtttcc agactggtca
     9781 gttgtggtgc tcaatggaaa gggcggggga tacaccaccg cgcggtgccc cgcccggcag
     9841 ggggcaccgg cagaaagcgg atgaaagggg tttgttcgtg cctgctttcc cacacagcac
     9901 cgcacgggcg cagacgactt cggtgcccga ggcgctggcg ttgcccgtga tcgaacaagc
     9961 gtttccgcga catcgtcatg agtattggcc aaagcttcag gtggagtccc gcgcctggct
    10021 gctcgaaaag cggctgatgc ccgccgacaa ggtcacccgc tatgcggacg aactccgcta
    10081 caccgacctc atcgccggct actacgtggg cgcgccgaag gatgtcatct cggcgatttc
    10141 cgacttcagc acctggttct tcgtctggga cgaccagcac gaccgcgacg ccgtccacgg
    10201 gcggcgcacc gcctggtacc ggctcagcgc cgaactgcac accgcgctgg acgcccccgg
    10261 cgaccacctc gcccacccgg agccgctggt cgcggccttc gccgagaccg tccaccggct
    10321 gaacggcttc ctcggccccg cctggaacga gcggttcgcc cgccatttcc acgccatcgt
    10381 cggcgcctac gaccaggaat tcgagaaccg ggtcaccaag gtcaccccga aggtcgccga
    10441 atacatcgaa ctgcgccgcc acaccttcgg ccactccgtc tggatcgacc ttctcgaacc
    10501 caccgcggga cgcgagattc ccgcggacct gaggacgagt ggcccctttc tcgcggcggc
    10561 ccggcactgc caggatttct ccgcctggta caacgacctc tgctcactcc cgaaagaact
    10621 cgcgggcgac gaccagcaca atctgggaat cagtctcata cgccatgagg gactgtcgct
    10681 cgaagaggcc gtggtggagg tgaggaaacg cgtggagaac tgcgtcaccg aattcgaggt
    10741 ggcggagaag gaattgcggg aactcctcgc cggacatctc gccgcactcc ccggaggagc
    10801 cggcaccgcc gaggcccggt ccgtcgccga agcggtcggg tcggccgtct tcaacatgcg
    10861 gaactggttc tcctccgtct actggttcca ccacgagtcc ggccgttacc gcgtcgacag
    10921 ctgggacgac cggagcaccc cgccctacgt cagcgatctg gcaggtgacg cgtgagcgcc
    10981 gaatccacca ccgaacgccc cgccaccccg ggcccgcgca ccccgcccct ggtggccggc
    11041 agcgtgcccg tcctcggcca cgccccgagc ctggtccgcg acccgctggc cttcctcacc
    11101 gggctgcgcg accacggcga cctggtccgc gtgaaactcg gcccgaagac ggcgtacgcg
    11161 gtctgcgcgc ccgagctggt cggggcgctg ctgcgcaact cccaggagtt ccaggtcggc
    11221 gggccgctct gggagaacct cgaagtgctg ctcggcaagg gggtggccac cagcaacggg
    11281 gccgaccacc gccgccagcg ccgcatgatg cagcccgcct tccggcccga gcggatcgcc
    11341 tcgtacgcga ccgtgatgga ggaggaggcg cgggcgatgg ccgaccgctg gcgggacggg
    11401 caggtggtcg acatcggcgc cgagacgttc agctgcgcgg tccgggtggt cgcccgctcg
    11461 ctgctggagg tcgactcgat cggcgccaag gcggaccgga tcagcgcctc gctgcacacc
    11521 gtcttcagcg gcctgtaccg gcggatgatc ctctccttcg gaccgctgca ccggctgccg
    11581 acccccgcca accggcgctt cgagcgggcg ctggccgacc tccaccacct cgtcgacgag
    11641 gtgatcgccg agcggcacgc gcagggcaag ggcgccgacg acctgctcga cattctgctc
    11701 acctccgagg acggcgaagg caggccgctc ggcgatcagg agattcacga ccatctcgtc
    11761 tcgctgatcg tcgccggggc cgaaaatgtc gcctcgacac tcgcctggtg cttccagctc
    11821 ctcaccgaac atccggccga ggaacagcgg gtggccgagg aggcactatc cgtggcaccg
    11881 gaccgaccgg tcaatttcgg cgatctgggc tccctcgacc acacccgcaa tgtcatcgtc
    11941 gaatcgatgc ggatacggcc cgcggcgtgg atattcactc gccgtgccgt cgcggacacg
    12001 gaactcggtg gctatcgcat tccagccggg gcggacatca tctacagcgc gtatgcgatg
    12061 cagcacgatc cgcgctcatt cgaccggccg gacgtcttcg acccggaccg gtggattcct
    12121 gaacgggccg aaaaggtacc gcagtacgcg atgatgccgt tcagcacggg caaccggaaa
    12181 tgccccggcg accacttcag catggtcgag gccacgctga tgctcgccac cgtactgccc
    12241 cgctggcggc tcgtccccgt ccccgagacc gacccggcgc cccggatcgg gatcaccctc
    12301 cagcccaagc gcgccgtctt ccgggtcgag agccgctgac ccgcacgcgc gccctgcacc
    12361 gacgcccgcc gcccggccct caggacgagg ggccgggcgg cgggcgtcgg cgttggcggg
    12421 gccggtcaga agtcgtcgtc gaaggagacg gttccctcga ccgcgacctg gtaggccgag
    12481 acccggcgct cgaagaagtt ggtcagctcc tgcacaccct gcagctccat gaaggagaac
    12541 gggttctgcg agccgtacac cggggcgaag cccagccggg tgagccgctg gtcggcgacg
    12601 cactccaggt actcgcgcat cgactcggtg ttcatgccgg gcaggccgtc cccgcacagg
    12661 tcccgggcga actgcagctc ggcctcgacg gcctccttga gcatcgcgac gacctgctcc
    12721 tggagcttgt cgtcgaacag ctccggctcc tccttgcgga ccgtgtcgac cacgtcgaag
    12781 gcgaagctca tgtgcatcgt ctcgtcacgg aagacccagt tggtgccggt cgccagcccg
    12841 tgcagcagcc cgcgcgagcg gaaccagtac acgtaggcga aggccccgta gaagaagagc
    12901 ccctcgatgc aggcggcgaa gcagatcagg ttgagcagga acttgcggcg gtccgcctgg
    12961 ctctccagct ggtccagctt gtccaccgag tccatccagc ggaagcagaa ctccgccttc
    13021 tcgcggatcg aggggatgtt ctccaccgcc gcgaaggcgt ccgcgcggtc ggccgggtcg
    13081 ggcaggtagg tgtcgagcag cgtcagatag aactggacgt gcacggcctc ctcgaagagc
    13141 tgacggctca ggtagagccg cgcctcgggg gagttgatgt gcttgtacag ggtcagcacg
    13201 aggttgttgg cgacgatcga gtcacccgtg gcgaagaagg cgaccagccg cccgatcagg
    13261 tgctgctcac ccggggagag cttcgccagg tcggcgacgt cggagtggag gtcgacctcc
    13321 tcgacggtcc aggtgttctt gatcgcgtcc cggtagcgct cgtagaagtc cgggtaccgc
    13381 atcgggcgca gggtcagctc gaagccgggg tcgagcaggt tcttcgccgc gccgacggtg
    13441 tgcgcgttcg ctgccggggt ggtgtcgggg gtggtcatta ctggcatgcc tcgcaggact
    13501 cggggttctc cagggagcag gcgatggcct ccgcgtcggg ggccgcctgc gccgggacgg
    13561 tggcggtggc gggggcggag ccgccggcgg cgcgggcgat ccgcgtggcc gggcgggacc
    13621 gcaggtagta cgtggtcttc agccccttct tccaggcgta cgcgtacatc gagctgagct
    13681 tgccgatggt gggcgtctcc atgaacaggt tgagcgactg gctctggtcc aggaacgggg
    13741 tccgggccgc cgccatgtcg atcaggccgc gctgcggcag ctcccaggcg gtgcggtaca
    13801 gcgcccgcag ctcctcggga atccacgcga agccctggac cgacccgctc gcctcacgca
    13861 gcgcctcgcg ggtgcgggcg tcccagacgc ccagccgctt caggtcctcc accaggtagg
    13921 agttgacctg gaggaactcc ccgctcagcg tctcgcgctt gaagaggttg gagacctgcg
    13981 gctcgatgca ctcgtagaca ccggcgatcg aggcgatggt ggccgtcggg gcgatggcga
    14041 ggagcagcgc gttccgcatg ccgctctccg cgacccgggc gcgcagcgcc tcccaccgct
    14101 ccggccaggc caggtcggtg tcgtagtggt ccgggtggag cacgccctgg gcggtgcggg
    14161 tgcggtccca gttcggcagc gggccgttct tctcggcgag gtcgcaggag gtctcgtacg
    14221 cggtgagcat gatgcgctcg gcgatccggg tggagagccg ctgggcctcg ggggagtcga
    14281 agggcagccg gagctggaag aagacgtcct ggagccccat cgcgcccagg cccaccggcc
    14341 gccagcggga gttggagcgc tcggcctgct cggtcgggta gaagttgatg tcgaccacgc
    14401 ggtcgaggaa gacgacggcg gtgcgcaccg cctcgtccag ccgctcccag tcgatcgcgc
    14461 cgccgtcgac gaaggcgccg aggttgaccg agccgaggtt gcagacggcc gtctcgccgt
    14521 cgtcggtgac ctccaggatc tccgtgcaca ggttcgagga gtgcacggtg tggcccggca
    14581 gcgccgtctg gttggcggtg cggttggagg cgtccttgaa ggtcatccag ccgttgccgg
    14641 tctgcgcgag ggtgcgcatc atccggccgt acagctcgcg cgccgggatg gtccgccggg
    14701 ccagcccccg cgcctcggcc gcgcggtagg ccgcgtcgaa ggcgtcgccc cacaggtcgg
    14761 tcagctcggg gacgtcggag ggggagaaga gcgaccagtc ggcgtcggcg tcgacccggc
    14821 gcatgaactc gtccgggatc cagtgcgcga ggttgaggtt gtgggtgcgc cgggcctcct
    14881 cgccggtgtt gtcccgcagc tccaggaact cctcgacgtc ggcgtgccag gtctccaggt
    14941 agaccgcggc cgcgcccttg cgccggccgc cctggttgac cgcggccacc gaggcgtcga
    15001 gcgtgttgag gaacggcacg atgccgttgg agtgcccgtt ggtgccgcgg atcagcgaac
    15061 cccgggcgcg gatacgggag taggcgaggc cgatgccgcc ggcgtgcttg gagagccggg
    15121 cgacctggtg gtagcggtcg tagatcgact ccagctcgtc cttgggggag tccagcaggt
    15181 agcaggagga catctgcggg tgccgggtgc cggagttgaa gagggtgggg gaggagggca
    15241 ggtaggagag ggcgctcatc agccggtaga gcgaggcgac ctcgtcgagg gcccgcaccg
    15301 agtcgtcctc ggcgaggccg caggcgacgc ggagcatgaa gtgctggggc gtctcgatga
    15361 cctggcgggt gtgcgggtgg cgcagcaggt agcggctgtg cacggtgcgc aggccgaagt
    15421 agccgaagcg gtcgtcggcc gccgggtcga ccagagcgtc gagccgctcg gcgtgcgcgg
    15481 tgacgaaggc ggcggtgcgg tccgcgatca ggccctcgcg gtggccggtg gcgaccgact
    15541 cggtgaaggt ggtgacgccc tggcccgcgg cctcctcggc gatggtgcgg gtcagcaggc
    15601 gggcggcgag ccgggagtag gcggggtcct cggagatcag accggcggcg gcctccgtcg
    15661 cgagcgaccg cagctcggcc tcgtccgagg cggcgttgcg gccccggagc gcggcggcgg
    15721 cgacccggcc ggggtcggtg tcggggagat ccgcggtgag gtcggtgagg gtacgcagca
    15781 gcgcgccccc ggggccctgg atctcctcgg cccgcacctc ggccgtcgac ggatcggctg
    15841 gcgcgatggt catgaagctc tccctcgctc ggctcggagc ctcgcggagg gcagcgggta
    15901 cgggcgggac gccgggctcg agggcacacg gctccgcacg cgtccgcgag cccattccac
    15961 gaggcccgga cgacatcggc acccggaccg gacggccggg tgcgctgttc ggcaggtctt
    16021 cggactcgcg ggtacgcgaa agcgcaccaa cacaccgttg cgggacagtt ccggacttcc
    16081 accggattcc cctgcggcga cagcgagcat gagcatacat cttgtgccgc gctcgcgaag
    16141 cggccccata tcttgtgtcg ggtgtgctgt gaggtgggtc attcgacccc acccgcaccg
    16201 gatgccccac cctcgcggag acgccctcgg gcggggccgg ggcgcccgtc ggacggggcg
    16261 tcagcgggcc gctgaggggc cgtcggcggg ccgtcggcgc cccggagggg gaacggcccg
    16321 ggggcgggcc cggagggatc tcacgggcgg cgcgcggagc tccacggcga cctcgcagag
    16381 cgtacgcgcc cggaccggtg cggcggtcgt cagggccccc ggcccgggaa acggcgaagc
    16441 cgccggcccc ctcgttcggg ggccggcggc ttcatccggc ggtcagcagc agcggaatcc
    16501 gtcgcgcggg tccgcctcgc gggcgtccat gcgactgcgt tcgaactgcc tgcgggtcat
    16561 cacctcggcg tccgggtcgt ggcgccggac gtgcgcggcg tacttctcgt acgccgtctc
    16621 gcccgacacc tcccggacgt accagccgat ccagcggacg ccggcgcgta cgcggtgggc
    16681 caggacgccg aggcgtccgg ggtggtgggc cgcctcgccg ctcatgcctg gccgccgccc
    16741 tgcttcgcgg gggcgtcgcc gtcgccgtca ccggcggagg cgggggctcc ggcgccgacg
    16801 agggccagtt cggccttctc ctcggaggtg gcgaacatcc cggccggggc gacgatcttc
    16861 gactgctcga agggcgcctc ggccagcttg accgactcgg gcttgcggat cgcgttgtag
    16921 ctgacgcggc ccgcgtcgac caggacgatg atgatcagca ccgcgaagac gatggacagg
    16981 acgccgtcca cggtggagtt ggtcaccacg gtgtgcatgt cgctcatcga cttggccggg
    17041 gccagcacct cgcccgcgtc gatgccgtcc tggtacttgg cgcgctgggc gaagaagccg
    17101 atcgccgggt tgtccgagaa gaccttctgc cagctcgcgg tgagcgtgac ggccacgtcc
    17161 caggcgagcg gtatgcccgt cacccaggcc cacttgaggc ggcccgactt gatcagcagc
    17221 gtggtgcaga cggccagcgc gacggcggcc agcagctggt tggcgatacc gaagagcggg
    17281 aagagctggt tgatgccgcc cagcgggtcg tggacgccga cccagaggaa gtagccccag
    17341 cagccgacga cgatcgccga ggtcagccag acgcccggcc accagctgac gcggcgcatc
    17401 ggcttccaga cgttgcccag ggtgtcctgg agcatgaagc ggccgacccg cgtaccggcg
    17461 tcgacggtgg tgaggatgaa gagcgcctcg aacatgatcg cgaagtggta ccagaacgcc
    17521 ttcatcccgg cgccgcccag cgcggccgcg aagatctcgg ccataccgag ggcgaaggtg
    17581 ggcgcgccgc cggtccgcga cagcagcgag gcctcctcga cgtccttcgc cgcctgggcc
    17641 agttggtccg ggctgatggt gaagccgagg ttggcgaccg cctccgaggc gctctggacg
    17701 gtgtcaccga ggacgccggc cggggagttg atcgcgaagt agaggcccgg gtcgatgatg
    17761 caggcggcga tcatcgccat gatggcgacg aacgactcgg tgagcatcgc gccgtacccg
    17821 atcatccgga tctgggtctc cttctggacc atcttcgggg tggtgcccga ggagaccagg
    17881 gagtggaagc cggagagcgc gccacaggcg atggtgatga agacgaacgg gaagagcgag
    17941 ccggagaaga ccgggcccgc gccgctggtc gcgaaggagg tgacgccgtc catcttcagc
    18001 gtcggcatcg cgatgatgac gcagaccgcc atcagcacga tcgtgccgac cttcatgaag
    18061 gtggagaggt agtcacgcgg ggcgagcagc atccagaccg gcagcaccga ggcgaagaag
    18121 ccgtagacca ccatccagat gaccagggtg cccggctcca gggtgaagaa gtccgccatg
    18181 gaggactcgg cgacccagcc gccgcccacg atcgccagca gcagcagggc gacgccgagg
    18241 acggagacct cggtgacctt gccggggcgc agcgtgcgca ggtagacgcc catgaagagg
    18301 gcgatcggga tggtcatgcc gatggagaag acaccccacg gcgagccggc cagcgcgttg
    18361 acgatgacga gggccagcac cgccagcagg atgatcatga tcatgaagac cgcgatcagg
    18421 gcggcgacac cgccgaccgg gccgatctcg tcccgggcca tctggccgag cgaacggccg
    18481 ttgcgccggg tggagaagaa gagggtgacc atgtcctgga cggcaccggc gaagatcacg
    18541 cccgccacga tccagatggt gcccggcagg tagcccatct gggccgccag gatagggccg
    18601 accagcgggc ccgcacccgc gatcgccgcg aagtggtggc cgaagagcac ccggcggtcc
    18661 gtcggctgga aatcgacgcc gttgtccagg cgctccgccg gggtggcccg gttcttgtcg
    18721 accttcagga ccttgttggc gatgaaccgc gagtagaagc ggtacgcgat ggcgtacgag
    18781 ccgagggccg ccgccagcat ccagatggcg gagatctcct cgccccggga gagcgccagt
    18841 acgctccagg cgatggcgcc gaccacggcg accaacgacc agacggcgat ggatttggcg
    18901 gacagcttcc ggtttccgga ggcgggtgga gccggctcgg ccatgatggt cccctcacat
    18961 gagcgctggc ggaaacacct gcgctgaact cctgcaatgc gtcggaaatg taggcgacag
    19021 gtccgggctt tgacaccccc tgtccgcgta tcggaacggc aacgacttca catccggcgc
    19081 aaccctgagc cgtggccgtc gcgtccccgc cccttacgca cgcctccccg cgcatttgtc
    19141 ccccgcgggg cgggcgcccc gcccgagcgg cccttcgccg atcacccccc aaccgtgacc
    19201 ttccgccggg gaggtgcgta ccccgcgccg cccggtggtc atgcgcggaa aagcacacac
    19261 gtacgagcga attgcccggc ggggctcagg cgggggcgag tggggtcatt accgggtggc
    19321 cggaaaatgg gcttcgattt cctgccaagt accccggggt tacccgtcgg cccgtatgcc
    19381 ggacatggga aagggcggca tccccggtga ggggtgccgc cccgctgtcc tccgtgcgcc
    19441 ggtcctactc caccggccgc ttcaggcggg ccaggaactt gtaccggtcg ccgcggtaga
    19501 ccgagcgcac ccactccacc ggcgcgccgc tctcgtcgcg ggagtggcgg gagagcatga
    19561 gcatcggcag gcccacgtcg gtggcgagca gggcggcctc gcgcggggtg gcgagcgagg
    19621 tctcgatggt ctcctcggcc tcggccgggc gcaccccgta gacctcgtag agcgccgtgt
    19681 agagagaggt gtacttgacc agggagcggc gcagggcggg gaagcgcttg gcggagaggt
    19741 gggtggtctc gatcgccatc ggctcgccgc tggccagccg gagccgctcg atgcgcagca
    19801 cgcggccgcc cgcggtgatg tcgagcaggg aggcgaggga gtcgtcggcg gtgatgtagc
    19861 cgacctccag cagctgcgag gtgggctcca ggccctgggc gcgcatgtcc tcggtgtagg
    19921 aggtcagctg gagcgcctgg gagaccttgg gcttggcgac gaaggtgccc ttgccctgga
    19981 tgcgttcgag ccggccctcg accaccagct cctggagcgc ctggcgcacc gtggtccgcg
    20041 aggtgtcgaa ctcggcggcg agcgtacgct cggggggcac ggaggtgccc ggcggcagcg
    20101 tccgcgtcat gtcgagcaag tgccgcttga gacggtagta cttgggcacc cgcgtggccc
    20161 ggaccggact ggtcggctcg gtggcgggct cgtcggccgt ccgggtcctc gtaccgcccg
    20221 cgtccgtcgt catggtccgc ctctccggct cctgtgctgc tgccgtcacc ggctcctccg
    20281 tctgtcgcgg atcacatcgt ggcacggccg gtgatcgccg gtccggactc cctcaggtgt
    20341 cggtccgata acggacgtga ctgcccttct tatacaccct tgacacccct aaaggtctag
    20401 gccaagctcc ggcttactgg tctacaccat taaagaccag atcccagtcc cacggcagta
    20461 actcgtcttc gatgtcatcg ctgcgggtgg ggggtagagg gttccctgag gagggtgacg
    20521 tgaagcgcaa gctcattgcg gccatcggtg tcgctggcat gatggccggt ctcgcggcgt
    20581 gcggggactc ggagacggcg agcaacgcca agcccgagga ccgcaaggaa aacctgaccg
    20641 tctggctgat ggtcgacgcc cagagcacct ggccggagct ggtcaaggac gtcaacgcgc
    20701 agttcaagaa gaagtacccc aatgtcaagg tgaacgtcca gtaccagggc tgggccgaca
    20761 aggccaagaa gctcgacacc gcgctcggcg gggacaagtt cccggacgtc gtcgagctgg
    20821 gcaacaccga gacgatgcag tacatcctca acggcgccct cgccgagatc gaccccaaga
    20881 agtacgagaa ctcggacacc tggatccagg gcctcaccga cacctgcacc ttcgagggca
    20941 agcagtactg cgtgccttac tacgccggtg cccgc
//
