LOCUS       NZ_BLIS01000012        23763 bp    DNA     linear   CON 26-AUG-2024
DEFINITION  Streptococcus canis strain FU1 ScFU1_contig12, whole genome shotgun
            sequence.
ACCESSION   NZ_BLIS01000012
VERSION     NZ_BLIS01000012.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptococcus canis
  ORGANISM  Streptococcus canis
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1
  AUTHORS   Yoshida,H., Katayama,Y., Fukushima,Y., Taniyama,D., Mizutani,T. and
            Takahashi,T.
  TITLE     Draft Genome Sequence of Streptococcus canis Clinical Strain FU1
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 171999)
  AUTHORS   Yoshida,H., Katayama,Y., Fukushima,Y., Mizutani,T. and Takahashi,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-DEC-2019) Contact:Haruno Yoshida Kitasato University,
            Kitasato Institute for Life Sciences, Laboratory of Infectious
            Diseases; 5-9-1, Shirokane, Tokyo 108-8641, Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC Genomics Workbench v. 6.5.1
            Genome Coverage                   :: 196x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009811695.1-RS_2024_08_26
            Annotation Date                   :: 08/26/2024 03:59:26
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,037
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,884
            CDSs (with protein)               :: 1,884
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 47
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 98
            CDSs (without protein)            :: 98
            Pseudo Genes (ambiguous residues) :: 0 of 98
            Pseudo Genes (frameshifted)       :: 42 of 98
            Pseudo Genes (incomplete)         :: 70 of 98
            Pseudo Genes (internal stop)      :: 33 of 98
            Pseudo Genes (multiple problems)  :: 38 of 98
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:23:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 136447
            Orig. end                         :: 160210
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BLIS01000012.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23763
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="2"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..23763
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23763
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13763](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13763)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     misc_feature    1203..1216
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.28"
                     /tool="antismash"
     gene            complement(1444..1947)
                     /locus_tag="GVO03_RS07470"
                     /old_locus_tag="ScFU1_14580"
     CDS             complement(1444..1947)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061038.1"
                     /locus_tag="GVO03_RS07470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_14580"
                     /product="QueT transporter family protein"
                     /protein_id="WP_159305105.1"
                     /transl_table=11
                     /translation="MLTLTVRDYVHIALVAALYVVLTITPPLNAISYGTYQFRVSEMLN
                     FLAFYHRKYIIAVTLGCMIANFYSFGLIDVFVGGGSTLVFVTLGVILFGKYQKDYLFNG
                     LFNKAFFYFSFFFAASMLTVAIELYFFGAPFFLTWFTTAVGELASLLIGSLIIDKLAKR
                     ITFY"
     misc_feature    1914..1929
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     regulatory      complement(1945..2062)
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            complement(2310..5129)
                     /locus_tag="GVO03_RS07475"
                     /old_locus_tag="ScFU1_14590"
     CDS             complement(2310..5129)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057467.1"
                     /locus_tag="GVO03_RS07475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_14590"
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="WP_159305106.1"
                     /transl_table=11
                     /translation="MLNRKFFTYASLLALVAVPTVVEEVVLQQHPVYAEEVLAPKAETP
                     AVTGVKEAGAATTPLTTIEDTKPAPTTSTVPQEAAGMGTEEMSVSPEVLANANGSQPIS
                     QVRTSPEGKPYTVTGKIISVVNGWGGNGFYIQDSNGTGLYIYPGKDLGYASGDIIQLTG
                     TLTNFKGELQLKSITAHKKLEGQLPTPVKETTIPELEKANPSTLVKLSNVTVGEIASDK
                     YETSSFKVTDKDGQSVAVRLDNRTGIKTSDLAAKIGSGDVINLTAILSTVDGNLQLKPF
                     TLDQFEVVKQAVRKEDTTPVGKLVKIGDIQGTSHTSPLLKKAVTVEQVVVTYLDDSTHF
                     YVQDLKGDGKVATSDGIRVFAKNAKVQVGDVLTISGEVEEFFGRGYEERKQTDLTITQI
                     VAKTVTKTGTAQVPAPLVLGKDRVAPANIIDNDGLHIFDPEEDAIDYWESMEGMLVAVD
                     DAKILGPLKNKEIYVLPGSSTRHLNNSGGVLLPANSYNTDVIPVLFKKGKQTIKAGDSY
                     KGRLAGPVSYSYGNYKVFVDDSKNMPDLMDGHLKPEKTNLQKDLSKLSIASYNIENFSA
                     NPSSTKDEKVKRIAESFIHDLNAPDIIGLIEVQDNNGPIDDGTTDATQSAQRLIDAIKK
                     LGGPTYRYVDIAPENNVDGGQPGGNIRTGFLYQPDRVSLSDKPKGGAKDALSWVNGELN
                     LSVGRIDPTNAAWKDVRKSLAAEFSFQGHKVIVVANHLNSKRGDNALYGRVQPVTFKSE
                     QRRHVLANMLAQFAKEGSKHQANIVMLGDFNDYEFTKTIQLIEEGGMANLVSRHDLADR
                     YSYFYQGNNQTLDNMLVSRNLLGHYDFDMVHVNSPFMEAHGRASDHDPLLLQLSFKKAS
                     NDEKVLVVPAPAATGQQKVAAKPLATAPKKVEKTLPKAGEKAGFVMTMLGITSMFASFS
                     LFGKGKEKQ"
     gene            complement(5473..6591)
                     /locus_tag="GVO03_RS07480"
                     /old_locus_tag="ScFU1_14600"
     CDS             complement(5473..6591)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057434.1"
                     /locus_tag="GVO03_RS07480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_14600"
                     /product="ABC transporter permease"
                     /protein_id="WP_093998496.1"
                     /transl_table=11
                     /translation="MSRFIKALFVKIRRKKTSYVTFILLPILTTLLALSLSFSGNSQAK
                     IGILDKDHSQISKQFIAQLKQTKKYDIFTKLEEEHIDNYLQDKSLEAVLTIDKGFSEKV
                     LTGKAQELKLRSIAKSEITEWFKAQANYLLENYNIMGDVAAGNQKTFDQILKKNKSLYY
                     QVNQVTLADRSRSKSVSSTTTGFLLILMLGSTSVIYGGILTDKSSHIYNRLVLSTLSRF
                     QYMLSYVCVGLVAFAIQLVIMLGLLKAFNVSFYIPMQMLLLVFFLFSLLAIGFGLLIGA
                     VTQNTQQSSQLANLIVMPTSMLAGCLWPLSITPSYMQAIGKLLPQNWVLSAITTFQSGG
                     GLSEAWPYLLALLATAATFIILSSLLLKPAQS"
     gene            complement(6588..7715)
                     /locus_tag="GVO03_RS07485"
                     /old_locus_tag="ScFU1_14610"
     CDS             complement(6588..7715)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985266.1"
                     /locus_tag="GVO03_RS07485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_14610"
                     /product="SagG family ABC transporter permease subunit"
                     /protein_id="WP_003047833.1"
                     /transl_table=11
                     /translation="MVLLHLIKKESLQIFRNRTALLMMVVFPIVMIVILSFAFKSSFNT
                     ATTVPKLTVRYQLEGEKTDYQKNFLAFLKVLNKELKLEAKPSKSLEADKKKVSEGALTA
                     TLEVKKNQSIKVTTNAINQQNADLINMLVTNYVDNAKTYDSIADLYPQRLAEIKKRKVD
                     FVKVSSVQTSKGMTSADYYAISMFTMITFYSIMSAMNLVLSDRQQRTTNRIHLTGVSPS
                     LLVFGKLIGAMLATTVQLGILYIFTRFVLRVNWGTNDWQIIGVTASLIYLSVAIGIGMA
                     TSISNESFLTVASNAVIPIFAFLGGSYVPLATLNSPLINQLSNISPIKWVNDSLFYLIF
                     GGQNNPIPVTLMVNISLGTVFILLALIGMRKQVTT"
     gene            complement(7724..8647)
                     /locus_tag="GVO03_RS07490"
                     /old_locus_tag="ScFU1_14620"
     CDS             complement(7724..8647)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016861.1"
                     /locus_tag="GVO03_RS07490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_14620"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_003047830.1"
                     /transl_table=11
                     /translation="MSFVQLTDVVKVYKGGKKAVDNVSMTIEEGKIYGLLGPNGAGKST
                     LINLILGLIPLTSGEVTILQQSQKAIRKISSQIGYVPQDIAVYPDLTAYENVELFGSLY
                     GLKGKQLKEQVLKSLAFVGLESQAKQFPSQFSGGMKRRLNIACALVHSPKLIIFDEPTV
                     GIDPQSRNHILESIRLLNSEGATVIYTTHYMEEVEALCDYIFIMDHGQIIEEGHKLELE
                     KRYAADLTNQILVTLTDPQQVEMSNRLGWSLTTADDESVLVIENGDIATVVRQLTEANI
                     GFSEIKHNHLNLEEIFLHLTGKKLRD"
     gene            complement(8669..9355)
                     /locus_tag="GVO03_RS07495"
                     /old_locus_tag="ScFU1_14630"
     CDS             complement(8669..9355)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047827.1"
                     /locus_tag="GVO03_RS07495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_14630"
                     /product="SagF family protein"
                     /protein_id="WP_003047827.1"
                     /transl_table=11
                     /translation="MMVVVLVAVLSLITLWLTSHRRRRLVRWHFKWIRILSYQNWLDVL
                     LGVVQFALLLVVLFLDLAGLRLGDVLTFLGQVTWQWGIMSYLLLYLLSLVEMTLLTLVL
                     IFDVGLQKDSRLLFQKLTWLAFKQEKPITSLLLLSFVVLADSVFYLGLLLLLGKGSLMS
                     LSVLVLGYALVKACRYSGWLNCLLAFCLFTVIGIWAVTATLLYGWLIGLLLLTLTYLMI
                     SFKEQR"
     gene            complement(9355..10026)
                     /locus_tag="GVO03_RS07500"
                     /old_locus_tag="ScFU1_14640"
     CDS             complement(9355..10026)
                     /EC_number="3.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047824.1"
                     /locus_tag="GVO03_RS07500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_14640"
                     /product="CPBP family intramembrane glutamic endopeptidase"
                     /protein_id="WP_003047824.1"
                     /sec_met_domain="Abi (E-value: 1.2e-11, bitscore: 38.3,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLFTQCLNLCFLLVTCCPSIPMQAVFGKGKNGYGFNLIAFLRAV
                     LVYYLIALMGIYLLSPEFSLSFGEIDATLILMGLGLSVLMLGVEVAFLHGLRCWQKRQW
                     LPLAFSFVGTTQEWNKLAYPLLLAFFEELTYRFLWFDILMNQWDLPLIVVLVLTSCCYA
                     LNHLLMGKSIFYAKLVTGFSYGSLYYLTGNLWLVVIIHVTSNLLVECLSHLQARHKKVV
                     D"
     gene            complement(10001..11359)
                     /locus_tag="GVO03_RS07505"
                     /old_locus_tag="ScFU1_14650"
     CDS             complement(10001..11359)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407460.1"
                     /locus_tag="GVO03_RS07505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_14650"
                     /product="YcaO-like family protein"
                     /protein_id="WP_159305107.1"
                     /sec_met_domain="YcaO (E-value: 1.1e-61, bitscore: 202.7,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 2.4e-104, bitscore:
                     342.4, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLQYYPSFNHIFDKLKGLSGNRTGILNQSQMPVCNHPHDVYLKSV
                     TGQMPDYHKQFIGELSQVSYHIIGYGSHYEEALIRYLGESIERYASIISGDLLSDRIVY
                     ASHKELSQTDRVMPLEYLQVFTQEQIERCLELSMVMCDKMVTEDDVLGWVKCPMFFEEQ
                     DMYVPVQMLCIGYKTNEAVGEKHVIPGFSTGTASHTTLEAAMCNSLIEYIQIDSMMLSW
                     HTKKPCPRIIIDDPDIQAILEEARLGKESLYEIIPIDMTVGDDNPLYTFGIILKNKYDE
                     GPYLLFGVQAGLDPKHTLLRGIMEAAAISYSYYYNLLYKKEALQNIESKNPLFLDLDSN
                     VFYYAHPKNQAHKWQAFEPLISGEILLSDLADHSGKDKKEELKILLAYTKKVSPNAVFL
                     DITPPEASEKGWYVTRVLTPELLEMCIPAFPFANHPRMRQFGGVTNAFVHPMP"
     gene            complement(11371..12435)
                     /locus_tag="GVO03_RS07510"
                     /old_locus_tag="ScFU1_14660"
     CDS             complement(11371..12435)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03603"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cytolysin_C_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060848.1"
                     /locus_tag="GVO03_RS07510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_14660"
                     /product="streptolysin associated protein SagC"
                     /protein_id="WP_093998495.1"
                     /sec_met_domain="Cytolysin_C_RRE (E-value: 1.2e-35,
                     bitscore: 115.1, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03603 (E-value: 3.9e-123, bitscore:
                     404.4, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYQLNSNVRIVQFQDTFCFRKGIWDFNEAVLDVSQEPQALKEAY
                     REIVTTLIEGGILDTDSYEKSLEAELFATFMEVITALYYNDVLMLEDDYALEENVMKVL
                     MGNFRFMATAGHTKNTDPVLFISDSTYVNESAKLLADQLQLPLQVASDDLKMLIQQTDV
                     SSRLDALTHHRSMKCLSEALKGYQSIVVCQERLNIMMLRHLNEISVALNIQLVLGFVDG
                     PFLHACTLNPPHSADFDSLERRVLARLQDHVLYQHFAQQALPTTQAVSQAYLPLLNVLM
                     NLVVSEAFIIAQTGSSKFEGRLLSIYLPTLEIQVQDILKMSNSQAQGALAKLKYEDQQI
                     STREIVRKLLSEEE"
     aSDomain        complement(12166..12435)
                     /aSDomain="Cytolysin_C_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing discrete C protein in a
                     SLS/cytolysin LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_GVO03_RS07510_Cytolysin_C_RRE.1"
                     /evalue="2.20E-36"
                     /identifier="RREFam014.1"
                     /label="GVO03_RS07510"
                     /locus_tag="GVO03_RS07510"
                     /protein_end="90"
                     /protein_start="0"
                     /score="115.1"
                     /tool="antismash"
                     /translation="MKYQLNSNVRIVQFQDTFCFRKGIWDFNEAVLDVSQEPQALKEAY
                     REIVTTLIEGGILDTDSYEKSLEAELFATFMEVITALYYNDVLML"
     gene            complement(12432..13382)
                     /locus_tag="GVO03_RS07515"
                     /old_locus_tag="ScFU1_14670"
     CDS             complement(12432..13382)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985278.1"
                     /locus_tag="GVO03_RS07515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_14670"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_159305108.1"
                     /sec_met_domain="PF00881 (E-value: 6e-27, bitscore: 88.1,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPFFAKGKTNSDNYPPLTLEKARQLFEFNTNHLSLSGYHHQTVLR
                     TSKQLVAQHLMPNETDNLSQRFLMNYKSNNSYLGFQASVVDFFTDSAVATFSSSAYFES
                     RENIIPLPKPTKITTALSTCITQRRSHRHFVDQEMPFQDLANLLYYACGVSAEAPIKDG
                     MPEKVTLRNCASGGGLYPITLIFYARNVSKLKDGFYEYLPYQHALRCHHISFEENIRAF
                     AEYGAINAESCNLVVIYVYHYLKNTRKYGNQATAYAFIESGEIAQNIQLTATALVYGSI
                     DIGGYNKEYLQEKLGLDGLNQHVIHMTLVGNKESQ"
     gene            complement(13602..13763)
                     /gene="sagA"
                     /locus_tag="GVO03_RS07520"
                     /old_locus_tag="ScFU1_14680"
     CDS             complement(13602..13763)
                     /codon_start=1
                     /gene="sagA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03602"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766767.1"
                     /locus_tag="GVO03_RS07520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_14680"
                     /product="TOMM family cytolysin streptolysin S"
                     /protein_id="WP_012766767.1"
                     /sec_met_domain="TIGR03602 (E-value: 6.6e-29, bitscore:
                     93.3, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLQFTSNILATSVAETTQVAPGGCCCCCTTCCFSINVGGGSAQGG
                     SGSYTPGK"
     misc_feature    complement(14071..14084)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 20.3"
                     /tool="antismash"
     gene            complement(14266..15573)
                     /gene="eno"
                     /locus_tag="GVO03_RS07525"
                     /old_locus_tag="ScFU1_14690"
     CDS             complement(14266..15573)
                     /EC_number="4.2.1.11"
                     /codon_start=1
                     /gene="eno"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /locus_tag="GVO03_RS07525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_14690"
                     /product="surface-displayed alpha-enolase"
                     /protein_id="WP_003047814.1"
                     /transl_table=11
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGE
                     HEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPNKG
                     KLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPIAFQ
                     EFMIMPVGAPTFKEGLRWGAEVFHALKKILKERGLVTAVGDEGGFAPKFEGTEDGVETI
                     LKAIEAAGYEAGENGIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQIDYLEE
                     LVNKYPIITIEDGMDENDWDGWKALTERLGGRVQLVGDDFFVTNTEYLARGIKENAANS
                     ILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSL
                     SRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK"
     misc_feature    15706..15720
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.32"
                     /tool="antismash"
     gene            15797..16252
                     /locus_tag="GVO03_RS07530"
                     /old_locus_tag="ScFU1_14700"
     CDS             15797..16252
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047813.1"
                     /locus_tag="GVO03_RS07530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_14700"
                     /product="DUF1694 domain-containing protein"
                     /protein_id="WP_159305109.1"
                     /transl_table=11
                     /translation="MDKLEDKVLKRALSDKRLDPDQQRYYLGTYAERVILSVPLAEATN
                     EKVKNYLETELPNLSMTYQPLALKISSELAPQYQILYMKLAKQHHLTATIVTEKHMTSP
                     FAFILHTDHAINLNETRLDIILKQFESERPIKQASEKPKSFWQKFFQ"
     gene            complement(16306..>16757)
                     /locus_tag="GVO03_RS07535"
                     /old_locus_tag="ScFU1_14710"
                     /pseudo=""
     CDS             complement(16306..>16757)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1026: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611514.1"
                     /locus_tag="GVO03_RS07535"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="ScFU1_14710"
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="LPNGDGKIYLSPVLDGYNSEIIDFTLSRSPDSKQVQTMLEKAFPA
                     DKYKGTILHSDQGWQYQHHFYHHFLESKGSRPSMSRKGNSPDNGMMESFFGILKFEIFY
                     EYENSYRSLDELEGAITDDIFTTTTNESKQN"
     gene            complement(17032..18756)
                     /gene="ezrA"
                     /locus_tag="GVO03_RS07540"
                     /old_locus_tag="ScFU1_14720"
     CDS             complement(17032..18756)
                     /codon_start=1
                     /gene="ezrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407454.1"
                     /locus_tag="GVO03_RS07540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_14720"
                     /product="septation ring formation regulator EzrA"
                     /protein_id="WP_159305110.1"
                     /transl_table=11
                     /translation="MSSGIILLIVAIVLLVIIAYLVGVIIRKRNDSLITSLEERKQALF
                     ALPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLTLNSFADIENHICEAENLNDTFNFI
                     RAKHEINSVESQLNLVEEDIASIREALGILKEQEEKNSARVTHALDLYEKLQASISENE
                     DNFGSTMAEINKQMTNIETEFSQFVALNSSGDPVEASEVLDRAEEHTIALGQITEQIPA
                     IVAKLEDDFPDQLDDLESGYRRLLEENYHFPEKNIEARFQEIRESIRANSSELVTLDLD
                     RAREENTHIQERIDSLYELFEREIAAYKVAAKNSKILPSYLAHAKRNNEQLKNEISRLS
                     RKYILSENEGLNIKAFDRDIKEIEESTLKIAEQFSMQEKPFSELQVIFERSMKTLASVE
                     SGQMDVFEAVKDIEKIESHARQNLEIYVTQLHMIKRYMEKRNLPGIPQDFLSTFFTTSS
                     QLEALMDELSRGRINIEAVSRLSEVAMVAIANLEELTYQVVQNATLTEQLLQYSNRYRS
                     FEAGVQNSFEHALRLFEVDNDYQASFDEISYALETVEPGVTDRFVNSYEKTRERIRF"
     misc_feature    complement(18936..18952)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.0"
                     /tool="antismash"
     misc_feature    complement(19016..19031)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.5"
                     /tool="antismash"
     gene            complement(19107..21059)
                     /gene="gyrB"
                     /locus_tag="GVO03_RS07545"
                     /old_locus_tag="ScFU1_14730"
     CDS             complement(19107..21059)
                     /EC_number="5.6.2.2"
                     /GO_component="GO:0005694 - chromosome [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="gyrB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /locus_tag="GVO03_RS07545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_14730"
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="WP_125073815.1"
                     /transl_table=11
                     /translation="MIEENKQVEEKAQEYDASQIQVLEGLEAVRMRPGMYIGSTSKEGL
                     HHLVWEIVDNSIDEALAGFATHIKVLIEADNSITVVDDGRGIPVDIQAKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVRVYKNGQIHYQEFKRGAVVADL
                     AVIGTTDTTGTTVHFTPDPEIFAETTEFDYKVLAKRIQELAFLNRGLKISITDKRLGME
                     QEEHFHYEGGIGSYVEFLNDKKDVIFNTPIYTDGELDGVAVEVAMQYTTSYHETVMSFA
                     NNIHTHEGGTHEQGFRTALTRVINDYAKKNKILKENDDNLTGEDVREGLTAVISVKHPN
                     PQFEGQTKTKLGNSEVVKITNRLFSEAFQRFLLENPQVARKIVEKGILASKARIAAKRA
                     REVTRKKSGLEISNLPGKLADCSSNDASQNELFIVEGDSAGGSAKSGRNREFQAILPIR
                     GKILNVEKATMDKILANEEIRSLFTAMGTGFGADFDVSKARYQKLVIMTDADVDGAHIR
                     TLLLTLIYRFMRPVLEAGYVYIAQPPIYGVKVGSEIKEYIQPGIDQEEQLKTALEKYSV
                     GRSKPTVQRYKGLGEMDDHQLWETTMDPDNRLMARVTVDDAAEADKVFDMLMGDRVEPR
                     REFIEENAVYSTLDI"
     gene            complement(21060..21620)
                     /locus_tag="GVO03_RS07550"
                     /old_locus_tag="ScFU1_14740"
     CDS             complement(21060..21620)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990461.1"
                     /locus_tag="GVO03_RS07550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_14740"
                     /product="HAD-IA family hydrolase"
                     /protein_id="WP_159305111.1"
                     /sec_met_domain="HAD_2 (E-value: 2.7e-20, bitscore: 66.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYHDYIWDLGGTLLDNYEISTQAFVQTLAFFNLSGEHDAVYQKL
                     KESTAIAVATFAPNQPQFLQEYKQNEAVKLAQPIWCLGAKEILAKIVASGARNFLVSHR
                     DQQVNQLLRNAGLLDYFTEVVTASNGFARKPNPESLLYLKDKYDISSGLVIGDRNLDKQ
                     AGQAAGFDTLLVDGRKNLLEIVA"
     gene            complement(21722..22933)
                     /locus_tag="GVO03_RS07555"
                     /old_locus_tag="ScFU1_14750"
     CDS             complement(21722..22933)
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056811.1"
                     /locus_tag="GVO03_RS07555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_14750"
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="WP_099983017.1"
                     /transl_table=11
                     /translation="MSQRKSIERRIDYAIVFPVFCLLVLGLVSIYVATSYDFPRHVSSV
                     MLQQILWIVIGTSLAFVLMFFSTEVLWKLTPYLYLLGIGLMVLPLIFFSHQLVAATGAK
                     NWITIGSLTLFQPSEFMKIAYILLMARVTVWFKGRKKRYHFKDDWKLLGLYFLVTLPVM
                     ALLALQKDLGTAMVFLAILAGLILISGISWWLILPLGLIVLALIATFFLVFLFPEGKDL
                     LLKLGMDTYQLNRISAWLTPFAFSETIAYQQTQSMISIGSGGFFGKGFNVLELSVPVRE
                     SDMIFTVIAENFGFIGAALLLMLYLLLIYRMLKVMFESNNLFYTYISTGFIMMILFHVF
                     ENIGAAVGILPLTGIPLPFISQGGSALISNLIGVGLILSMNYQHVLARDKESERELKRR
                     VRYH"
     tRNA            complement(23162..23233)
                     /anticodon=(pos:complement(159645..159647),aa:Arg,seq:cct)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="GVO03_RS07560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="ScFU1_t00090"
                     /product="tRNA-Arg"
     gene            complement(23162..23233)
                     /locus_tag="GVO03_RS07560"
                     /old_locus_tag="ScFU1_t00090"
     gene            complement(23398..23745)
                     /gene="rplS"
                     /locus_tag="GVO03_RS07565"
                     /old_locus_tag="ScFU1_14760"
     CDS             complement(23398..23745)
                     /GO_component="GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA]"
                     /GO_component="GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rplS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /locus_tag="GVO03_RS07565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_14760"
                     /product="50S ribosomal protein L19"
                     /protein_id="WP_003047792.1"
                     /transl_table=11
                     /translation="MNPLIQSLTEGQLRSDIPSFRPGDTVRVHAKVVEGTRERIQIFEG
                     VVISRKGQGISEMYTVRKISGGIGVERTFPIHTPRVDKIEVIRHGKVRRAKLYYLRALQ
                     GKAARIKEIRR"
ORIGIN
        1 tgacaagatg ggcactggct tggaagccac atcggcactt gaccctgacg tttatcagag
       61 accacacgta aaacagcagg aataatatcc cctgccttat atacaatcac tgtatcgcca
      121 atacgaatgt ctttttctgc aatataatcc acattatgca gagtggcacg actaacggtt
      181 gtccccgcga gttggaccgg tgttaaatta gctgtaggcg tgaccacacc tgttcgtccc
      241 actgtccaat caaccgaaag gatttccgct tctttttcct ctgctggaaa tttgtaggca
      301 atggcccagc gtggggcttt aaccgtaaac cctagctctt cttgcatggc tagactattc
      361 accttgatga caatcccgtc aatatcataa gccaattgat ctcgttttgc ttctacagtt
      421 tggataaagt cccaaatctc agtcatggac gaggacaagt agcggcgcgg attaactgaa
      481 aatcctaaat cagctaactc agctaacact tcatcttgtt ggcttcgatt ggtcgggcta
      541 gcttcttgat ataaaaaagt agctaattgg cgtttttcaa cgacagttgt atctaattgt
      601 cgcaaggtac ccgcagcagc atttctagga ttggcaaatt cggtttcccc attttcctgg
      661 cgctcttcat taatagcttt aaaagactga cgagacatgt aagcctctcc tcgaacagtg
      721 atggttaaag gttcactcaa ttggtgagga atatccttaa tttttttgat attctctgta
      781 atattctcac cgatattgcc gtcgccccgt gttgccccaa cctgtaagaa gccattctca
      841 taactcaagg aaatagataa gccatcaatt tttaattctg ctagataggt ggcattcgga
      901 aattcagcct tgacacgctt atcaaatgca tctagctcct cacgtgaaaa agcatcctgc
      961 aaactaaaaa gcggatactg gtgctgatat ttctcaaaac cggttaggat ggttccacca
     1021 acctgctgag taggactatc ttgcaaaaca tactctggat agtctttttc aagagcaact
     1081 aattctcgat aaagtttatc gtagtcactg tctgaaacag agggggcatc attggtataa
     1141 tattcttggc ggtagcgatt aagcaactct gtcagttctc ttatgcgttt tttcatatcc
     1201 ttattttatc ataaaagaag gaaaataagc tatttccttg tcggaagaaa ataaaaaaga
     1261 tatttgaaaa actacacccc aaaaaccaac ctgagaaccc ccacaatagc ttttctttgc
     1321 ttaaaaaaac taaaaataaa gaccagtcac tcgtataaat cattaattta taccaagctt
     1381 gaaaagttaa caaaaaagag ctgggcattt gcctaactct tctcaatatc agtttatcag
     1441 tcgttaataa aaggtgatac gcttagctag cttatcaata atgagcgagc caatcagaag
     1501 cgaagccaat tctcccacag ctgtggtgaa ccaagtcaaa aagaatggag ccccaaagaa
     1561 atacaattca atcgctacgg taagcataga agctgcgaaa aaaaacgaaa agtaaaagaa
     1621 tgccttgtta aagagaccat taaagagata atctttttga tacttgccaa ataaaatcac
     1681 tcccaaagtg acaaaaacaa gggtcgatcc gccaccaaca aagacatcaa tcagcccaaa
     1741 gctgtaaaaa ttagcaatca tacatcccaa agtcactgca ataatgtact tacgatggta
     1801 aaaagctaga aaattcaaca tctcagatac tcgaaattga tacgtgccat aagaaatagc
     1861 atttaagggt ggggtaatgg ttaggaccac atatagagca gccaccaaag caatgtgaac
     1921 ataatcacgt acggttaatg taagcatttt ttctcctttg acgtcaggat agtcctcaac
     1981 ggatctacct acgtttctaa tatgcttggt gaaagggaac taagcaccaa gggttgcaaa
     2041 gcaacagtta cattgtacca caaaaagatt atcttgacaa agcccatcac atttcatttc
     2101 ctttatccca aaatgcaaaa atcttcccca cttgttccct atcacacggc atcaaggcct
     2161 ttatattctc ttctatcagt taatctggtt gattcctaag ccagttccat taaaaaacgt
     2221 cacctgcttc ttccatcaag aaacaaaaag gcccgagata gttctcagac ctgtaacgaa
     2281 ccactatggg attcaaagac tttccgtgtt tattgttttt ccttaccttt accaaacagg
     2341 ctaaaggaag caaacatgct ggttattcct aacatagtca tcacaaagcc agctttttcc
     2401 cctgcctttg gcaaggtttt ttctactttc ttaggagcag tagctaatgg ttttgctgcc
     2461 accttttgct gaccagtagc cgctggcgct ggcacgacta gaactttttc atcatttgat
     2521 gcttttttaa aagacaattg gagcaacaat gggtcatggt cagacgcacg accatgcgct
     2581 tccataaatg gagaattcac atgaaccatg tcaaagtcat agtgaccaag caaattgcgt
     2641 gaaactaaca tattatcaag ggtttggtta tttccttgat agaagtatga ataacgatct
     2701 gcaagatcat gtcggctcac caagttagcc ataccccctt cttcaatcaa ttggatggtc
     2761 tttgtaaatt cgtaatcgtt aaagtcacct aacatcacaa tattagcttg gtgttttgac
     2821 ccttcttttg caaattgtgc taacatatta gccaagacgt gacgtctttg ctcagattta
     2881 aaagtgactg gttgcacacg accataaagg gcattatccc cacgtttaga attcaaatgg
     2941 ttggcaacga caatgacttt atgaccttgg aagctaaatt ctgctgccaa tgatttccga
     3001 acgtctttcc aagcggcatt ggttggatca attcgaccaa cactgaggtt taattctcca
     3061 ttaacccaag atagagcatc cttagcacca ccttttggct tatcagaaag gctgacgcga
     3121 tctggttgat aaaggaatcc agttcgaata ttaccacctg gttgacctcc gtcaacatta
     3181 ttttctggag caatatcaac ataacgatag gttggcccac ctagtttttt aatggcatca
     3241 atgaggcgtt gcgcactttg tgtcgcatct gttgtcccat catcaatcgg cccgttatta
     3301 tcttgcactt caattaatcc aataatgtct ggagcattta gatcatgaat aaaggattcg
     3361 gcaatccgtt tgaccttctc atctttagtt gaagaaggat tggctgagaa gttctcaata
     3421 ttgtaagaag caatgcttaa cttgctaagg tctttttgca agtttgtttt ttcaggtttt
     3481 aaatgaccgt ccattaaatc tggcatgttt ttgctgtcat caacaaagac cttgtaattg
     3541 ccatagctat aagatactgg cccagctaat cttcctttgt aagagtcgcc tgctttaatg
     3601 gtttgtttgc cttttttgaa aagaacagga atcacatctg tgttataaga attagctgga
     3661 agtaatactc cacctgaatt attcaagtgt cttgtactgg aaccaggcaa gacatagatt
     3721 tctttatttt tcaatggacc aaggatttta gcatcatcaa ctgccactaa catgccttcc
     3781 attgattccc aataatcaat agcgtcttct tctggatcaa agatgtgtaa gccatcatta
     3841 tcaataatat tggctggtgc gacacgatct ttccctaaaa caagcggtgc tggaacttga
     3901 gctgtccctg ttttggtcac tgttttagcc acaatttgag tgatggtaag atcagtctgc
     3961 ttacgttcct cataaccacg accaaagaat tcttctacct cacctgaaat ggtcaaaaca
     4021 tcaccgactt gaaccttagc gtttttagca aaaacacgaa tgccatctga agtcgcgacc
     4081 ttgccatctc ctttcaaatc ttgaacataa aaatgagtgg aatcgtctaa ataagtgaca
     4141 acaacctgtt ctacggtgac cgcttttttg agaagtggcg atgtatggct agtgccttga
     4201 atatctccaa ttttaacaag cttaccaact ggtgtagtat cttcttttct cacagcttgt
     4261 tttaccactt caaattggtc aagggtaaat ggtttcaatt gtaagttacc atcaactgtt
     4321 gacaagatgg cggtcaagtt gatcacatca cctgaaccaa tcttagctgc caagtcagat
     4381 gttttgatgc cagtacggtt gtctaagcgt accgccacac tctgaccgtc cttatccgta
     4441 accttaaagg aagatgtttc gtacttatca gaagcaatct ctcccactgt tacattggat
     4501 aacttaacaa gggtggacgg gtttgctttt tctaattctg gaatagttgt ttctttaaca
     4561 ggagtaggaa gttgcccttc caattttttg tgggcagtaa tgcttttgag ctgtaactca
     4621 cccttgaaat tagtaagggt acctgttagt tggataatat cgccactagc atatcccaaa
     4681 tctttcccag gatagatata gagccctgta ccattactgt cttgaatgta gaagccattg
     4741 ccaccccaac cattgacaac actgattatt ttacctgtta cagtataagg ttttccttca
     4801 gggctagtcc taacttgtga aatcggctgg ctaccattag cattcgccaa tacttcagga
     4861 ctgacagaca tttcttctgt gcccattcct gctgcctctt gtggaacagt tgatgtcgtc
     4921 ggagctggtt tggtgtcctc aatagttgtt aagggagttg ttgcagcacc tgcctcttta
     4981 acaccagtta cagcaggtgt ttctgcctta ggagcaagta cttcctctgc atagacgggg
     5041 tgttgttgca aaacaacttc ttcaacaacg gtaggaacag caaccaacgc tagcaatgaa
     5101 gcataagtga aaaatttcct gtttaacata aaaactcctt ttgtttaatg cgtttcatac
     5161 atgcttattg taacaaaaag aattggtaaa ataaatacat tttttaacat tttgtttcaa
     5221 aaagttaatg ttattaaaag tttaatcgtt atcatatcaa caaaaaagag aattacttca
     5281 ctaaaaaaca aacattgcag cagaaataat gacaaaaaaa gaaagagttc ttaaaaatca
     5341 agaagaatct tagaaactta atcgtttttc agcaaaaaaa gcatcaactt tagtgacgaa
     5401 agagccgtta aattgatgct atcgcttctt ttattaatac accgtaaaga aagataacct
     5461 tccccaaatg ccttatgatt gggcaggttt taataataaa ctagaaagga ttataaaggt
     5521 tgctgcagtt gccaacaagg ccaacaagta aggccaagct tctgataaac caccaccact
     5581 ctgaaaggtc gttatcgctg ataaaaccca attttgcggt aataattttc cgatagcttg
     5641 catgtaagaa ggggtaatag ataaaggcca caaacaccct gctaacattg acgttggcat
     5701 cacaatgagg ttagccaact gactactttg ttgagtattt tgtgttacgg caccaatcaa
     5761 taagccaaaa cctattgcca ataaactaaa gaggaagaaa actaataaga gcatctgcat
     5821 tgggatgtaa aaactaacat taaatgcttt caataagccg agcataatca caagttggat
     5881 ggcaaaggca acaagaccca cgcaaacata actaagcatg tattgaaagc gggataatgt
     5941 tgacaagacc aagcggttat agatatgact tgacttgtct gttaaaatac cgccgtaaat
     6001 cacactggta cttcctaaca tcaaaatcaa taaaaagcct gttgtagtgg aggacacgga
     6061 tttactacgt gagcggtctg ccaaagttac ttggttaacc tgataatata gactcttgtt
     6121 tttcttcaga atctgatcaa aggtcttttg attcccagca gccacatccc ccataatatt
     6181 gtaattttct aaaaggtaat tggcttgcgc tttaaaccat tctgtgatct cgctcttagc
     6241 aatagagcga agtttgagtt cttgcgcctt acctgtcaac actttctctg agaacccttt
     6301 atcaatagtg agcacagcct ctaaagattt atcctgaagg taattatcaa tgtgttcttc
     6361 ttctaattta gtgaagatgt catacttttt agtttgttta agttgggcaa taaattgctt
     6421 tgaaatctgg ctatggtcct tatccaaaat accaatttta gcttggctgt tgcctgaaaa
     6481 actcaaagag agagccaata aagtggttaa aataggcaac aagatgaagg tcacataact
     6541 ggtttttttc cgtcgtattt taacaaataa cgcttttata aaacgactca tgtggtcacc
     6601 tgctttctca ttcctattaa agcgagtaga ataaagactg ttccaagact aatattaacc
     6661 atcaaggtca ctgggattgg attgttctgc cctccaaaaa taaggtaaaa caaactatca
     6721 ttaacccact tgatgggaga aatattggac aattgattaa tcaaaggact atttagagtt
     6781 gctaaaggaa cgtagcttcc tcccaaaaag gcgaagatag gaataactgc atttgaagcc
     6841 accgtcaaga aagattcatt gctaatacta gtagccattc cgataccaat agccacagac
     6901 aggtaaatca aagaagctgt tactccaata atttgccagt cattggttcc ccaattaact
     6961 cgcaaaacaa acctcgtaaa gatataaaga atgcccaact ggactgtcgt cgccaacatg
     7021 gctcctatca attttccaaa aacaagaagg ctaggcgaaa cacctgtgag gtgaatacga
     7081 ttagtggtgc gctgttgtcg gtcggataag acaagattca tcgctgacat gatgctataa
     7141 aaggtaatca tggtaaacat ggaaatggca taataatcag ccgaagtcat tcctttgctg
     7201 gtctgaacag aacttacttt aacaaaatcc actttgcgtt tttttatctc tgctaatcgt
     7261 tgaggataaa ggtcagctat tgagtcatag gtcttagcat tatccacata attggtcacc
     7321 agcatgttaa tcaagtcagc attctgctgg ttaatcgcat tggtggttac cttaatgctt
     7381 tggtttttct tcacctctaa agtggcagtc aatgctcctt cactaacctt ctttttgtcc
     7441 gcttcaagcg acttgctagg tttagcttct agtttcaatt ccttatttaa aacctttaag
     7501 aaggcaagaa agttcttctg ataatccgtc ttctcccctt ccaattgata acgcaccgtt
     7561 aatttaggaa ctgtcgtcgc tgtgttaaaa ctggatttaa aggcaaaact taaaatcaca
     7621 atcatcacaa ttggaaaaac caccatcatc aataaggctg ttcgatttcg aaaaatctgc
     7681 aaactttctt ttttgattaa atgtaataaa accataataa cctctaatct cttagcttct
     7741 tacccgttaa gtgcaagaag atttcttcta aattcaagtg gttatgttta atctcactaa
     7801 atccaatatt agcctctgtt aattgacgaa ctaccgtagc aatgtcacca ttttcaatca
     7861 ctaaaactga ctcatcatca gcagttgtca agctccagcc tagtctgttg gacatctcca
     7921 cctgttgagg gtctgtcaaa gtcactagaa tctgattggt caggtcggca gcatagcgtt
     7981 tttccagttc aagcttatga ccttcctcaa taatctgacc atggtccatg ataaagatat
     8041 aatcacaaag agcttcgact tcttccatgt aatgggtggt gtaaataacc gtagctcctt
     8101 ctgaattcaa aaggcgaata gattctaaaa tatgatttcg agactgcggg tcaatcccaa
     8161 cagttggttc atcaaaaata attagtttgg gagaatgaac caaagcacag gcaatattca
     8221 agcgtctctt cattcctcct gagaattgac taggaaattg tttggcttgg gattctagac
     8281 ctacaaaagc taaacttttt aaaacttgct ctttcagttg ctttcctttt aaaccataca
     8341 gcgatccaaa aagttccaca ttttcataag cggttaaatc agggtagaca gcaatatctt
     8401 ggggaacata gccaatttgt gagctaattt tgcgaatagc cttttgagat tgctgtaaaa
     8461 tagtgacttc cccagaagtc aagggaatta agcctaaaat cagattaatg agggtagact
     8521 tacccgcacc atttggtcct agcaaaccgt aaatcttacc ttcttcaatg gtcatcgaga
     8581 cgttgtcaac agccttttta ccacctttat agactttaac aacatctgtt aattgcacaa
     8641 aactcatata ctactccttt tttcaacctt accgttgctc tttaaaacta atcatcagat
     8701 aagtcagggt caataataac aaaccaatca accaaccata taatagagtg gctgttaccg
     8761 cccaaatccc aatcaccgta aagagacaaa aggctaaaag acaatttaac caacctgaat
     8821 aacgacaggc cttcaccaaa gcataaccta aaactagcac ggacaaactc attaatgagc
     8881 cttttcctaa caaaagtaat aaacctaaat aaaagacact atcagccaat acaacaaaac
     8941 tgagtaagag caaactagtt attggcttct cttgtttaaa agctaaccac gtcagctttt
     9001 gaaacagcaa gcgactatct ttttggagtc caacatcaaa gataaggacc aaagtcaaaa
     9061 gtgtcatttc taccaaggac agtaagtata atagcaaata gctcataatt ccccattgcc
     9121 aagtgacttg tcccaaaaag gtcaagacgt ctcctaacct aagacccgca aggtctaaaa
     9181 acaagacaac gagaagaaga gcaaattgca ccacacccag taggacatct agccagttct
     9241 gataggacaa gattcttatc catttaaaat gccatctgac caaacgacgt ctccgatgac
     9301 tggtcaacca aagcgttatt aaacttaaaa cagctactaa aactactacc atcattagtc
     9361 caccaccttc ttatgtcttg cttgaagatg actaaggcac tcgaccaaca aattgcttgt
     9421 aacatgaatg atgacaacca accacagatt cccagtaagg taataaaggc tgccgtaact
     9481 aaaacccgtt accaatttag cgtagaaaat ggattttccc atgagcaaat ggtttaaggc
     9541 gtaacaacaa ctggtcaaca caagcaccac aataagtggc aggtcccatt ggttcattag
     9601 gatatcaaac cataaaaaac gataggttag ttcttcaaaa aaagctaaaa gcaagggata
     9661 agccagcttg ttccattctt gtgtcgtccc aacaaaggag aaagccaagg gaagccactg
     9721 ccgtttttgc cagcagcgaa gcccatgtaa gaaggccact tcaaccccta acatcaaaac
     9781 actcaatcct agtcccataa gaatgagggt tgcatcaatt tcaccaaagg ataagctaaa
     9841 ctcaggtgat aataaataaa tacccattaa agcgattaag tagtaaacaa gaactgctct
     9901 tagaaaagca atgagattaa acccatagcc attctttcct ttcccaaata ccgcttgcat
     9961 gggaattgag gggcaacagg tcaccagtaa gaaacaaaga ttaaggcatt gggtgaacaa
    10021 aggcattcgt cacacctcca aactgtctca ttcgtggatg attagcaaaa ggaaatgctg
    10081 gaatacacat ttcaagaagt tcaggggtta agacacgggt tacataccaa cctttttctg
    10141 atgcttcagg aggggtaatg tccagaaaga cagcatttgg gctgactttt ttagtatatg
    10201 ccaataatat tttcaactct tctttcttat ccttaccaga atgatctgcc aaatcactaa
    10261 gcaggatttc tcctgaaatc aaaggctcaa aagcctgcca tttatgggcc tgatttttgg
    10321 gatgggcata ataaaacaca ttgctatcca aatctaaaaa gagagggttc ttgctctcaa
    10381 tattttgaag cgcttctttc ttatataaga gattatagta ataactgtaa ctaatagctg
    10441 ccgcctccat gattcccctt agtaaggtgt gtttaggatc caagccagct tggaccccaa
    10501 ataagagata gggaccctca tcgtatttat ttttaaggat aatcccaaag gtgtaaagcg
    10561 ggttgtcatc gcctacggtc atatcaatag gaataatctc atacaagctc tcttttccca
    10621 atcttgcttc ttctaaaatc gcctgaatat cagggtcatc aataataatt ctaggacaag
    10681 gctttttggt gtgccaactc agcatcatgg aatcaatttg aatatactca atcaggctat
    10741 tgcacatagc tgcttctaac gtagtatgag aagctgtacc tgttgaaaaa cctggaataa
    10801 catgcttttc acccacagcc tcattagttt tataaccaat gcagagcatc tgaaccggaa
    10861 cgtacatgtc ttgctcttca aaaaacatag gacacttaac ccaacccaag acatcatctt
    10921 ctgtcaccat tttgtcgcac ataaccatgc tcaattccag acaacgttca atttgttcct
    10981 gagtaaagac ctgtaaatac tctaacggca tcactcggtc tgtctgactt aattccttat
    11041 gagaagcata gactattcga tccgacaata aatcaccaga aataatactc gcataacgtt
    11101 caatgctttc ccctaaatat ctgatcaggg cttcttcgta atggctgcca taaccgataa
    11161 tatggtagct gacctgactc aattccccaa taaattgctt atgataatca ggcatctgac
    11221 cagtcacact ctttaagtaa acatcatgag ggtgattaca aacaggcatt tgcgattgat
    11281 ttaaaatacc tgtccggtta ccacttaagc ctttgagttt atcaaaaata tgattaaagg
    11341 aagggtaata ctgtaacata acgatcctcc ttattcttct tcactaagga gttttctaac
    11401 aatctcgcga gttgatattt gctgatcctc atattttaat tttgccagag caccctgtgc
    11461 ctgagaattt gacatcttca gaatatcttg aacctgaatt tcaagggttg gcaaatagat
    11521 acttagcaaa cggccttcaa attttgaact acctgtctga gcaataataa aagcttcgct
    11581 aaccaccaaa ttcattaaaa cattgagcaa gggcaaataa gcttgactca ccgcttgtgt
    11641 cgttggcaag gcctgctgag caaaatgctg gtaaagaaca tggtcttgca atcgagccaa
    11701 aacccttctt tccaaactat cgaaatcagc actatgagga ggatttaggg tacaagcatg
    11761 taagaaggga ccatccacaa aacctaacac cagttgtata ttaagagcca cactaatctc
    11821 attcagatgg cgtaacatca taatattcaa tcgttcttga caaacaacaa tactctgata
    11881 accctttaaa gcttcagata aacacttcat actacggtga tgggtcaagg catccaaacg
    11941 agaactaaca tcagtttgtt ggattagcat tttcaaatcg tcactagcca cttgcaaagg
    12001 taattgcagt tggtcagcta acagtttggc cgattcatta acataggttg aatcactgat
    12061 aaaaaggaca ggatccgtat ttttggtatg tcctgctgtt gccataaatc gaaaattccc
    12121 cattaagact ttcatgacat tctcttcaag ggcataatca tcttctaaca taagcacatc
    12181 attataatac aaagctgtga tgacttccat aaatgtcgca aataattcag cttccaaact
    12241 cttctcatag gagtcagtat caagaatgcc accctcaatc aaggttgtca caatttctcg
    12301 ataagcctct tttaaagcct gaggttcttg cgaaacatct aagacagctt cattaaagtc
    12361 ccagataccc tttctaaaac aaaaggtatc ctgaaattgg acgatacgaa cattactatt
    12421 tagttggtat ttcattgaga ctccttattt cctacaagtg tcatgtgaat cacatgctgg
    12481 tttagtccgt ctaaccctaa tttttcttgg aggtactcct tgttgtaacc tccaatatca
    12541 atactgccat aaacgagggc agttgctgtc aattgaatat tttgagctat ctcacctgat
    12601 tcaatgaaag cataggcagt tgcttgattg ccatatttgc gtgtgttttt gaggtaatgg
    12661 tatacataaa tgacaacaag attgcaactt tcggcattaa tagcaccata ttctgcaaag
    12721 gctctaatat tttcttcaaa actaatatga tggcacctta aggcatgttg gtaaggtaga
    12781 tactcataga aaccatcttt tagtttactg acatttctag cataaaaaat caaagtaatg
    12841 gggtataagc ctcctccaga agcacaattt cttagggtaa ctttttctgg cataccgtct
    12901 ttaatgggtg cttcagcact gaccccacaa gcatagtaaa ggaggttagc caaatcctga
    12961 aaaggcattt cctgatctac gaagtgacga tgactccttc tttgggtaat acaggtcgaa
    13021 agggcagttg ttatctttgt tggtttgggc agaggaataa tgttttctct actttcaaag
    13081 taagcactac ttgaaaaagt tgccaccgca gaatcagtaa aaaagtcaac cacgctagct
    13141 tgaaatccca agtaactatt attactcttg taattcatta aaaaacgttg actcagattg
    13201 tctgtctcat tcggcattaa atgttgagca actaactgtt ttgatgtcct tagcaccgtt
    13261 tgatggtgat agcctgataa agataagtga ttggtattaa actcaaataa ttgtcttgcc
    13321 ttctccaatg ttaaaggagg ataattgtct gaattggttt ttccttttgc aaaaaatggc
    13381 atatctatct ttcctgtctt actctacgaa catatagtaa ttagcaggta ccaagtagca
    13441 cctgctaatt acctagagac attagaacca aaacgattac cactgcctca tgtcctaaca
    13501 cccctattta agataagtca catcagctgt tactcatcgt aacctagtcg ctagcaaacc
    13561 aatcacactg atatcaccat caaatagaga tattaaatag attatttacc tggtgtatag
    13621 ctaccgctac caccttgagc actaccgccc ccaacattaa ttgagaagca acaagtagta
    13681 cagcagcagc aacaacctcc aggagcaact tgagttgttt cggctacgct agtagctaaa
    13741 atatttgaag taaattgtaa cataacgctt acctccttat ccaacaaata aataaacaac
    13801 tgataaaaat acaaatagtt gtttttaggt aaactcaaag agttattaca aaacaaggct
    13861 agctatattg tactgttgta acgaaacaac tatccaattc ttatcatcta tattatagta
    13921 aaaaatgact taaatgtaaa ccctttctta ccattattag caaaaaataa caaaaaaatc
    13981 ggtatgattc taaattataa gtcccctccc cttactaaat gtccagctga taagaaagca
    14041 aagactttca gaaacaaaaa acagataaca ttagacccta tcctctgaat ggtgaaccaa
    14101 cagcgaacta aactatcaca agggaatagt cctaagaaaa gtcaactttc catttggtgt
    14161 ttcactccta ggtgttaaag aaagatttaa aacaaaaaag caccttggga aagcgcccca
    14221 aagtgcttaa tatcaaggct ttacgcccct aatctcgata agagattatt ttttaaggtt
    14281 atagaatgat ttgatgcctt tatattgagc cacttcacca agttgatctt cgatacgaag
    14341 caattggttg tatttagcaa tacggtctgt acgtgacaat gaacctgtct tgatttggcc
    14401 agcgttagtt gcaactgcga tgtcagcgat tgttgaatct tcagtttcac ctgaacggtg
    14461 tgatacaacg gcagtgtatc cagcttcttt agccatttca atagcttcaa acgtttcagt
    14521 caaagtaccg atttggttaa ccttgataag gattgagtta gctgcatttt ctttgatacc
    14581 acgagcaagg tattcagtgt ttgtaacgaa gaaatcgtca ccaaccaatt gaacacgtcc
    14641 gcctaggcgt tcagtaagag ctttccaacc atcccagtca ttttcatcca taccatcttc
    14701 gatagtgatg attgggtatt tgttaaccaa ttcttcgagg tagtcgattt gttctgcaga
    14761 tgtacgaaca gcagcgcctt caccttcaaa tttagtgtaa tcgtaaactt tacgttcttt
    14821 gtcgtagaat tctgatgatg cacagtcaaa accaatcatg atgccgtttt cgccagcttc
    14881 gtaaccagca gcttcgatag ctttaagaat ggtttctaca ccatcttcag ttccttcaaa
    14941 tttaggcgcg aatccacctt catcaccaac agctgtaaca agtccgcgtt ctttaagaat
    15001 tttcttaaga gcgtggaaaa cttcagcacc ccaacgaaga ccttctttga aagtaggtgc
    15061 accaacaggc atgatcatga actcttggaa tgcgattgga gcatctgagt gagaaccacc
    15121 gttgatgata ttcatcatag gagttggaag aactttagtg ttgaatccgc caagataagt
    15181 gtaaagtggc acttcaaggt agtcagcagc tgcacgagca acagcaatag aaacaccaag
    15241 aatagcatta gcaccaagtt tacccttgtt aggagtaccg tcaagtgcga tcattgcacg
    15301 gtcgatagct tgttgatcgc gaacatcgta accgatgatt gcttcagcga taatgttgtt
    15361 aacgttatca acagcttttt gtgtaccaag accaaggtaa cgagatttgt caccatcacg
    15421 aagttcaaca gcttcatgtt caccagttga agctcctgaa ggaaccatac cacgtccgaa
    15481 tgcacctgat tctgtataaa cttctacttc aagtgttggg ttaccgcgtg agtcaaggac
    15541 ttcgcgagcg taaacatcag taataattga cattataata ctctccttat gagttttaat
    15601 attttacatg ttaataatac cacaaactag gcctttaatc aacttaaaaa gcaactttat
    15661 gaaagcgcca ttcaatttcc agattgacat tcaagatatt tcatttattt acagaaaatt
    15721 cacctatgga gatgatattg gcattttccc ctgcaaatcg gtataatgaa agaaatagga
    15781 agatatgagg cgttttatgg ataaattaga agataaagta ttaaaaagag cattgagtga
    15841 caaaaggcta gaccccgatc aacaacgcta ctacttaggt acctatgccg aacgggttat
    15901 tttaagtgtg cccttagcag aggccacaaa tgagaaggtt aaaaactatt tagaaaccga
    15961 gttaccaaac ctgagcatga cctaccagcc tttggctttg aaaatttctt cagagttagc
    16021 accacaatat caaatacttt atatgaaatt ggctaagcaa caccatctga ctgctaccat
    16081 tgtaacagaa aaacacatga cctctccttt tgcttttatt ctccataccg atcacgcgat
    16141 aaatctgaac gaaacacgtt tagacattat tttaaaacag tttgaaagcg agcgccccat
    16201 caaacaagcc tccgaaaaac ctaaatcctt ctggcaaaaa ttttttcagt aacttaaaaa
    16261 gacaaactca atatttgtac cgcccttaaa aagttggaca agaaattatt gaaaggattt
    16321 aattctgtat tgtacagggc tgagtccttt taattttgct ttgattcgtt tgttgttgta
    16381 gtaaaaatat catctgtgat cgctccttcc agttcatcaa gagaccgata agagttttca
    16441 tactcataaa atatctcgaa ttttagaatg ccaaagaagg actccatcat gccattgtca
    16501 ggactgttac ccttacgaga catagaagga cgactgcctt tactctctaa aaaatgatga
    16561 taaaagtgat gctgatactg ccacccttga tcgctgtgaa gaatggttcc cttgtactta
    16621 tcagctggaa aagctttctc aagcatggtt tgaacttgct tggaatccgg tgagcgagac
    16681 aaagtaaaat caataatttc gctattataa ccatcaagaa caggggatag atagattttc
    16741 ccatcaccgt ttggtaaagg cttccttaaa ccccaaccgc ccagccatca gcttcttccg
    16801 ttagaactga tatttcctga gcatgtcctg cttcttgacc aagtaagtta ataacttcct
    16861 cttaaatcaa gaccacatct aaaactaatc atcttttaac agctaccata cactctcttt
    16921 cttttacact aaatacgact aattaattca gtttagcatt atcccatagc tctttggggt
    16981 taaggaactg ctaccaaaaa agccgcgaca aagagtcacg actttaagct atcagaaacg
    17041 aatccgttca cgtgtttttt cgtaggaatt gacaaaacga tcagtgacgc caggctctac
    17101 cgtttcaagc gcataagaaa tttcatcaaa ggaggcttga taatcattgt ctacctcaaa
    17161 cagtctcaaa gcatgttcaa aactattttg aacgccagct tcaaaagaac ggtatcggtt
    17221 agaatactgt agcagttgct ctgttaacgt cgcattttga accacttggt aagttaattc
    17281 ttctaagttt gcaatagcaa ccattgcaac ctctgataaa cgtgaaactg cttcgatatt
    17341 aatacgtcct ctactgagtt catccatcaa ggcttccaac tgagaactcg ttgtaaagaa
    17401 agtgctaagg aaatcttgtg gaatgcctgg caaattacgc ttttccatgt aacgtttgat
    17461 catgtgaagt tgagttacat aaatctctag gttttgacgc gcatgcgatt cgattttttc
    17521 aatgtcttta accgcttcaa agacatccat ttgaccagat tccactgaag ctaaagtctt
    17581 catgctacgt tcaaaaataa cttgtaattc tgagaatggt ttttcttgca tgctaaactg
    17641 ctctgcaatt ttaagcgtac tctcttcgat ttccttaata tccctgtcaa aagctttaat
    17701 gttgagtccc tcattttcgc tcaaaatata tttgcgagac aagcgagaga tttcattttt
    17761 taactgctca ttattacgtt tagcatgtgc caaatagctt ggtaaaatct tgctattttt
    17821 agctgctacc ttataagctg caatttcacg ttcaaagagt tcataaaggg aatcaatacg
    17881 ctcttgaata tgagtatttt cttctctagc acggtccaaa tccaaagtca ctaattctga
    17941 agagttagca cgaattgact cgcgaatctc ttggaaacgg gcttcgatat ttttttctgg
    18001 gaaatggtaa ttttcttcga gtaggcgacg gtaaccagac tctaaatcat ctaattgatc
    18061 tgggaaatca tcttctaact tagcaacaat agctggaatt tgttcggtaa tctgtcccaa
    18121 agcaatggta tgttcttcag ctctatcaag cacctcagaa gcttctactg gatcacccga
    18181 tgaattaaga gcgacaaatt gtgaaaactc cgtttcgata ttcgtcattt gcttgttaat
    18241 ctcagccatg gtagaaccaa agttgtcttc attttcagag atagaggcct gcagcttttc
    18301 atacaaatca agggcatgtg tgacccgtgc actatttttt tcttcttgtt ctttaagaat
    18361 accaagcgct tcacgaatag aagcgatgtc ttcttcaaca agatttaatt gactttcaac
    18421 gctattaatt tcatgcttgg cacggataaa gttgaaagta tcatttaagt tttcagcttc
    18481 acaaatatga ttttcaatat cagcaaaaga attgagggtc aagtccaccc acttttggtt
    18541 ccattcacga aaagacgttt gactttgtcc aatcaaatga agtgatttta cttcttcgat
    18601 ttcatcattg acaggtaggg caaacaaggc ctgttttcgt tcctctagac tggtaattag
    18661 tgaatcatta cgttttcgta taatgacacc tactagatag gcgataatca ctagtaggac
    18721 tatggccaca atcagcaaga taattccgct tgacatctga atctccttat taattagatg
    18781 cgatttgtca acgtttgttt cagcaaaatc tgaaactcct taatcgcctt ttattaaaat
    18841 tttatcaaaa atacactata acgttacgat tataacatac tttcaagtgc atttcaaaac
    18901 atatttgacc aattcaacaa tctccaataa gtgctttaca aggcatttac aatagagact
    18961 agcataggtg tcaaagctct gcctcaacac ctattcgtta gcactatttt tagacatgac
    19021 cacacagtcc atttgccatc agacatcgtg acattaattc ttcttgttag cttagagata
    19081 ggcttagtac tggggtaaga aaatggctaa atatccaatg tactataaac cgcattctct
    19141 tcgataaatt cacgtcttgg ctctacacga tcgcccatta acatatcaaa taccttatct
    19201 gcctcagctg catcatcaac agtaacacga gccattaagc gattatcagg atccattgtt
    19261 gtttcccaga gttggtgatc gtccatttct ccaagacctt tataacgctg aacagttggt
    19321 tttgaacggc ccacactata tttttcaaga gctgttttta gttgctcttc ctgatcaatg
    19381 cctggttgaa tgtattcttt aatctcacta ccaactttca ccccgtagat aggtggttgg
    19441 gcaatgtaaa cgtaacctgc ttctaagact ggtctcatga agcgataaat caacgttaac
    19501 agtaaggtac gaatatgagc gccatccaca tcggcatcag tcataatcac taacttttga
    19561 taacgagctt ttgacacatc aaaatctgca ccaaagcctg ttcccatagc ggtgaagaga
    19621 cttctaattt cttcgttagc aagaatctta tccatggttg ctttttccac atttaagatt
    19681 ttaccgcgga taggcaagat ggcttgaaac tctcggttac gacctgattt agctgatccg
    19741 cctgcggagt ctccttcgac gatgaacagt tcgttttgac tagcatcgtt tgacgaacag
    19801 tctgccaatt taccaggtaa gtttgaaatt tctaagcctg attttttgcg ggtgacttca
    19861 cgagcgcgtt tagctgcaat tctagctttg gaagccaaaa tccctttttc cacaatctta
    19921 cgagcaactt gtgggttttc caaaagaaaa cgttggaagg cctcactaaa gaggcggtta
    19981 gtgattttaa ctacttctga attgccaagt tttgtttttg tttggccttc aaactgaggg
    20041 tttggatgtt tgacagaaat gactgctgtt aagccttcgc gaacatcttc ccctgttaaa
    20101 ttgtcatcat tttctttgag gattttattt tttttcgcat agtcattgat gactcgagtg
    20161 agggctgttc gaaaaccttg ctcatgggtt ccgccctcat gagtatgaat attattggcg
    20221 aaactcatga ctgtctcatg ataactagtt gtgtattgca tggcgacttc tacggcaacg
    20281 ccatctaatt caccatcggt ataaatggga gtattgaaaa tgacatcttt tttatcgttt
    20341 aaaaattcaa catatgagcc aataccacct tcataatgga aatgctcttc ttgctccata
    20401 cctaatcgtt tatctgtaat ggagattttc aaaccacggt ttaaaaaggc taattcttgg
    20461 atacgtttag ctaaaacctt gtaatcaaac tccgttgtct cggcaaaaat ctcagggtct
    20521 ggagtaaagt gaacagtcgt tccagtagta tcagttgtcc caataacagc aagatctgct
    20581 acgacagcac cacgtttaaa ttcctggtaa tgaatctgac catttttata aacacgtaca
    20641 tctaactggg tggacaaggc attaacaaca gaggaaccta caccatggag acctcctgac
    20701 actttgtagc cgcccccacc aaatttacct cccgcatgca agacggtaaa gaccgtttca
    20761 acggcaggac gccctgtttt agcttgaata tcaactggaa taccacgacc atcgtccacg
    20821 actgtgattg aattgtctgc ctcaataagc accttgatat gagtcgcaaa accagctaat
    20881 gcttcatcaa tagaattatc aacaatttcc catactaaat gatgtagccc ttctttagac
    20941 gttgatccga tatacatccc aggacgcatt cggacagctt ctagcccttc taaaacctga
    21001 atctggctgg catcatattc ttgtgctttc tcttcaactt gtttgttttc ttcaatcatc
    21061 tatgctacta tctccaatag gttttttcta ccatcaacaa gcaaggtgtc aaaacctgct
    21121 gcttgtcctg cttgtttatc cagattacga tctccaataa ccaagccact actaatatca
    21181 tatttatctt ttaaataaag taaactctct gggtttggct tacgagcaaa gccgttagaa
    21241 gccgtcacaa cctccgtgaa ataatctaaa agccctgcat ttcgcaagag ttggttgact
    21301 tgctgatcac gatgggatac taaaaaattg cgcgcacccg aagcaactat ctttgccaaa
    21361 atttctttag ctcctaaaca ccagataggc tgagctagct ttactgcttc attttgcttg
    21421 tactcttgta aaaattgtgg ctgattgggc gcaaaagttg ccaccgcaat agccgttgat
    21481 tcctttaatt tttggtaaac agcatcgtgt tcacctgaaa gattaaaaaa ggcgagggtt
    21541 tgaacgaagg cttgggttga aatttcgtaa ttatcgagta aggtaccacc caaatcccat
    21601 atataatcgt gataattcat acctttcatt ataccacaca ttcacccaat attatagtca
    21661 tttccataaa ttaaaagagg gcaagtagcg acttgtttga caagtattac ttcccctctt
    21721 actaatgata tcggacacgt ctctttaatt ctctctcact ttctttgtca cgtgccaaca
    21781 catgctggta attcattgac aatattaaac ccactccaat caaattggaa atcaaagccg
    21841 accctccttg agaaataaag ggaagaggaa ttcccgtcaa aggtaaaatc ccaacagctg
    21901 caccaatatt ttcaaaaaca tgaaataaaa tcatcatgat aaaacctgtt gaaatatagg
    21961 tgtaaaagag attattggac tcaaacatta cctttaacat ccgataaatc aagagcagat
    22021 aaagcattaa caataatgca gcaccaataa agccaaaatt ctcagcaatc acagtaaaaa
    22081 tcatgtcgct ttctctgaca ggaactgaca actccaaaac attaaaccct tttccaaaaa
    22141 agccaccact gccaatagaa atcatgcttt gtgtctgctg gtaggcaatg gtttctgaaa
    22201 aagcaaaagg ggttaaccaa gcagaaatac gattaagctg gtaggtatcc attcctaatt
    22261 tcagcagtaa gtcttttcct tcaggaaata aaaagacaag gaaaaaagtt gctattaatg
    22321 ctagaacaat gagtcccaag ggaagaatca gccaccaaga aattcctgaa atcaaaatca
    22381 agccagccaa aatggccaga aaaaccatgg cagttcccaa atctttttgc aaagcaagca
    22441 aggccattac cggaagagtg actaggaaat aaagtcctaa taatttccaa tcgtccttga
    22501 aatgataacg tttttttcta cccttaaacc aaactgtcac ccttgccatc agtaaaatat
    22561 aagcaatctt cataaattcc gaaggttgaa ataaggttaa cgaaccaatg gtaatccagt
    22621 ttttagcccc tgttgcagca actagctggt gactaaagaa aatcaagggt agaaccatca
    22681 gaccaatccc caatagataa agataagggg tcaacttcca cagaacttct gtactaaaaa
    22741 acatcaaaac aaaagccaaa gaggtaccaa taactatcca tagaatctgc tgcaacatga
    22801 ctgatgagac atgccgggga aagtcgtaac tagtcgccac ataaatagag acaagcccca
    22861 acactaataa acaaaaaaca ggaaatacaa tagcataatc aatgcggcgt tcaatagact
    22921 tcctttggga caaaaggcaa cctcctttta ctacaacccg attggtagga ccgaccttac
    22981 tccaaacctg ttagcctaaa atgaaaaaga gcccctaatc taagagcaaa gtggcacgtc
    23041 ttcaacagtt tttggaggaa actgtcttgg cttttcaaca acaggagaca catttagtat
    23101 aaaccatctc ctttgacatc taattgctct cctcatctag ctagatgagt gaacctttaa
    23161 atgacccctg ccggaatcga accagcaact actccttagg agggagttgt tatatccatt
    23221 gaactaaggg gtctctaaaa atcattacct tatctattgt aacctagaaa aagggggaat
    23281 gcaagattaa acctcagata acttaagcct tctgtacttt ttctttgccg ttcaaaaaaa
    23341 caaaaaaaag accagaatta tctagtcttt taccatctga tggcactggg actcatttta
    23401 acgacggatt tctttgatgc gagcagcttt accttgtaat gcacgtaagt agtaaagttt
    23461 cgcacgacga actttaccgt gacggataac ttcgatttta tcaacacgtg gtgtgtggat
    23521 tgggaatgta cgttctaccc cgataccacc tgagatttta cgaacagtgt acatctctga
    23581 gatcccttga cctttacgtg aaataacaac accttcaaaa atctggatac gttcgcgagt
    23641 tccttcgaca acttttgcgt gaacgcgaac agtgtcacca ggacggaagc tagggatatc
    23701 agagcgaagt tgaccttctg tcaaactttg gattaatgga ttcattttta ttctcctatc
    23761 tta
//
