LOCUS       NZ_BLIS01000011        20999 bp    DNA     linear   CON 26-AUG-2024
DEFINITION  Streptococcus canis strain FU1 ScFU1_contig11, whole genome shotgun
            sequence.
ACCESSION   NZ_BLIS01000011
VERSION     NZ_BLIS01000011.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Streptococcus canis
  ORGANISM  Streptococcus canis
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1
  AUTHORS   Yoshida,H., Katayama,Y., Fukushima,Y., Taniyama,D., Mizutani,T. and
            Takahashi,T.
  TITLE     Draft Genome Sequence of Streptococcus canis Clinical Strain FU1
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 251486)
  AUTHORS   Yoshida,H., Katayama,Y., Fukushima,Y., Mizutani,T. and Takahashi,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-DEC-2019) Contact:Haruno Yoshida Kitasato University,
            Kitasato Institute for Life Sciences, Laboratory of Infectious
            Diseases; 5-9-1, Shirokane, Tokyo 108-8641, Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC Genomics Workbench v. 6.5.1
            Genome Coverage                   :: 196x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009811695.1-RS_2024_08_26
            Annotation Date                   :: 08/26/2024 03:59:26
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,037
            CDSs (total)                      :: 1,982
            Genes (coding)                    :: 1,884
            CDSs (with protein)               :: 1,884
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 47
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 98
            CDSs (without protein)            :: 98
            Pseudo Genes (ambiguous residues) :: 0 of 98
            Pseudo Genes (frameshifted)       :: 42 of 98
            Pseudo Genes (incomplete)         :: 70 of 98
            Pseudo Genes (internal stop)      :: 33 of 98
            Pseudo Genes (multiple problems)  :: 38 of 98
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:23:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 133900
            Orig. end                         :: 154899
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BLIS01000011.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20999
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20999
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20999
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10999](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10999
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    954..970
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.7"
                     /tool="antismash"
     gene            complement(<1192..>1478)
                     /locus_tag="GVO03_RS06230"
                     /old_locus_tag="ScFU1_12120"
                     /pseudo=""
     CDS             complement(<1192..1478)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560726.1"
                     /locus_tag="GVO03_RS06230"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="ScFU1_12120"
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLAVRQPLIQEGLRHLNN"
     gene            complement(1562..1732)
                     /locus_tag="GVO03_RS10180"
                     /old_locus_tag="ScFU1_12130"
     CDS             complement(1562..1732)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GVO03_RS10180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ScFU1_12130"
                     /product="hypothetical protein"
                     /protein_id="WP_201281567.1"
                     /transl_table=11
                     /translation="MPKKIIKAFGAVGKLISIIPDTTEIIGKTIDNSRPIIEKRMESKH
                     EREIYFIFVFL"
     misc_feature    complement(1769..1783)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.95"
                     /tool="antismash"
     gene            1899..2861
                     /locus_tag="GVO03_RS06235"
                     /old_locus_tag="ScFU1_12140"
     CDS             1899..2861
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S41"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057564.1"
                     /locus_tag="GVO03_RS06235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_12140"
                     /product="S41 family peptidase"
                     /protein_id="WP_159305013.1"
                     /sec_met_domain="Peptidase_S41 (E-value: 7.1e-30, bitscore:
                     97.7, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRYMKVLSLLGIPLMIILSIGIYGIQRYGPNFNLYLFPPSAQKY
                     GDIALERLDMLGLYAQGEKWDKTRQETHKALKKAKSYKEAQQILQKAVSVAGGKHSSLV
                     SKNSFQKSLVDQQKPVAQVEGGILYLKVPAIEGLAPKTLTAYANKLNTPLTKNYKGAIV
                     DLRGNTGGNMTPMLIGLSGLLPDGDLFSFEDKYRNKQVVELQGKELVNQDSIALDKPVV
                     KQDIPVAVLIDHQTASSGEMTAFAFQGLENTLFFGEPTAGYTTGNNVIPLYDGALLVIT
                     SSRIINRQGQVYENNPIFPDRNSQDPLADAKQWLSEVTK"
     gene            2899..3651
                     /locus_tag="GVO03_RS06240"
                     /old_locus_tag="ScFU1_12150"
     CDS             2899..3651
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650232.1"
                     /locus_tag="GVO03_RS06240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_12150"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_003048482.1"
                     /transl_table=11
                     /translation="MLLEINHLEKVFRTRFSKEETRALQDVDFKVDKGEFIAIMGESGS
                     GKTTLLNILATLEKPTNGSVCLNGIDITKIKENRLAAFRLQNLGFVFQDFNLLDTLSVR
                     DNIFLPLVLNRRPIKEMEARINQIAPQLRIDTLLDKRPFEISGGQKQRVAIARSLITKP
                     QLLLADEPTAALDYRNSEELLTLFEEINRSGQTILMVTHSANAASHANRVLFIKDGRIF
                     HQIYRGNKNNLDFNKDISIAMTGLLGGE"
     gene            3653..5608
                     /locus_tag="GVO03_RS06245"
                     /old_locus_tag="ScFU1_12160"
     CDS             3653..5608
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1243: ABC
                     transporter, permease component"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057562.1"
                     /locus_tag="GVO03_RS06245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_12160"
                     /product="FtsX-like permease family protein"
                     /protein_id="WP_159305014.1"
                     /transl_table=11
                     /translation="MFYLKLAWNNLRNSLSVSAPFLLASTVLYMLNCIVHIILMSPISE
                     NMKHGKILLGLGAFILILFALIMEVYSYRFLLNQRSREFGLYNMLGMNKKQVSWVSTLE
                     LILMYFVTVGVGSLLSAIFSHLFYLIFVNLVHSTNLTLQFQIGAFILTAFIFAFIFGFL
                     ALVGLLKIGKTSPLMLFRDSEKGEKEPRGNFLLAGLSIISLSVGYYISLTSSTLTAFET
                     IIRFFIAVIIVIVGTYLFYISFMTWYLKRRRQNKTYFYQPEHFVSTSQMIFRMKQNAVG
                     LANITILAVMAFISIATTTALYTNTEVMTEQLFPRNSKITFDNNTLTNQDEIFQKVVLD
                     KIDKKASDFLIYKDTMITFEISRASKIVVTKKDVMHPNIAKIGFVYLVTQDDFRSLGNK
                     LPQLKTGQTAFYKQKGDSQLTEIELLGHHFKNVLNLKTVQFPAVANTYNPGVLVVSDKT
                     TLDNVQETFKKITNYGFEPSITAYADLTKEEIAKILDDKGTISDNGQFIGNIETKEDYR
                     LGVYALSGGFLFTGFLLGFSFILGAALIIYYKQYSEGHEDQKSYKILQEVGMSKDQVKK
                     TINSQILLVFFMPIALAVLHFCAALVMLKQMLLLFGVLDSTLIYLVSAITIGLIICLYF
                     IIYKMTSRTYYRIIER"
     gene            5652..6317
                     /locus_tag="GVO03_RS06250"
                     /old_locus_tag="ScFU1_12170"
     CDS             5652..6317
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060151.1"
                     /locus_tag="GVO03_RS06250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_12170"
                     /product="response regulator transcription factor"
                     /protein_id="WP_099982946.1"
                     /transl_table=11
                     /translation="MTKHDKIYIIEDDTTILSLLDNHLSQAYHVRTVTNFRDIKQEVLT
                     YQPDLILMDITLPFFNGFYWTTEIRKQSTVPIIFISSSNDEMDTVMALNMGGDDFVSKP
                     FSLTILDAKIAAFLRRSQQFTSDDISLDQFKLHFDGTLSNGEDTVTLSPTEHKMLTILM
                     TRNQEIVSKEEILEKLWENDNFIDHNTLNVNMTRLRKKIGSIGFDRIHTVRGVGYLIK"
     gene            6314..7261
                     /locus_tag="GVO03_RS06255"
                     /old_locus_tag="ScFU1_12180"
     CDS             6314..7261
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766937.1"
                     /locus_tag="GVO03_RS06255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_12180"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_159305015.1"
                     /transl_table=11
                     /translation="MILAFLKEYRSFYLQYGLTILIYWVVFYLYHLPMAYFTTANWIAL
                     TILVLNSLWQYYQFKEKIKILQEFIYVKELDTLTLPSEKAYRALIVKLKEAEADHLLQH
                     INKQKNMEALIKMWSHQMKLPLSALSLMIQTQNTDLKEYQQQVYRLEQYLNSLLSYLKF
                     KQHQDDFRFQAVSVRAVVSSVIKKSSQLCIAKNISMEIQGDWQVKTDKKWLSFALTQVI
                     DNAIKYSNKGGHISISIKEGSMSISDNGIGILKEDLPRLFDEGFTGFNGHEHQKATGLG
                     LYMTKQILDQLNLDIQIESVVGEGTKVIVFPLKK"
     gene            complement(7329..7871)
                     /locus_tag="GVO03_RS06260"
                     /old_locus_tag="ScFU1_12190"
     CDS             complement(7329..7871)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048489.1"
                     /locus_tag="GVO03_RS06260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_12190"
                     /product="Gx transporter family protein"
                     /protein_id="WP_003048489.1"
                     /transl_table=11
                     /translation="MNKQSQKLLFITMLAAQAVVISFYERFIPTPFAFAPGAKLGIANL
                     ITILAIFTLKPMDSAKVIFLKLLLSTFLSGTFSTFLYGFSGTLLSFLVMLALKTLGPKR
                     VSVIGISTLGGIMHNVGQLLVFAFIARSWLVLNYLPILSFSGIISGFFVGLTGNYLLLK
                     VTPLKRFHQDLLDDWTF"
     misc_feature    8007..8018
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.06"
                     /tool="antismash"
     gene            8030..9922
                     /locus_tag="GVO03_RS06265"
                     /old_locus_tag="ScFU1_12200"
     CDS             8030..9922
                     /EC_number="1.6.5.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017007.1"
                     /locus_tag="GVO03_RS06265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_12200"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_159305016.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.7e-47, bitscore:
                     156.0, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHNIVIVGAGYAGIASARYLAKTFKKQQDVTITLIDKNSFQTYM
                     TELHEVAAGRVEPEAIKYDLQRIFKKYPKVQLVTDKVLAIDYDQQQVKAEHHTLDFDYL
                     ILAMGGEANDFGTPGVKEHGFSLWSIEAAETLHYHILDACYHAMKEHDVAKRRALLTFT
                     VIGAGFTGIEMIGELIDWVPILAKQFKLDINDFSLKVVEAMPSILNMVTEKEQTKAQKY
                     LIKKGVELILADGVASVDKDALYLSSGRKIDTYTSIWTAGVKANSDTSDFDIEKARGGR
                     LVANQYMETLEHPNVYVAGDLVYYEDGSQGGKPTPQIVQAAEQTGKTAAQNIAASIKKT
                     EKVSYKGKYDGFMVSIGSKYGVAYLMDKFHLSGFLAMAVKHFTNLLYFFTISSFFNIGA
                     YLRHEFFDIKNGRNIFGSNLSSKGNRLWLVPLRVFYGSLWLYEGVKKAFGLFGTESWFG
                     NKVVFPFPWLQKAAEVTSGASESGGDAVAKGASEMAKQVFGLSYTYGEEPMQVLKLMPH
                     WFESLMKFMMPNQEVALFMQKMMTCLEIAIGLALIVGAFVWLVSAATAALVVMFSLSGM
                     FYWVNIWFIPVAIALMAGAGRSFGLDYWIMPWLGNRLDRWIYGKPKHLYLKKNH"
     gene            10001..10999
                     /locus_tag="GVO03_RS06270"
                     /old_locus_tag="ScFU1_12210"
     CDS             10001..10999
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050642.1"
                     /locus_tag="GVO03_RS06270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_12210"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_003048493.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 7.8e-47, bitscore:
                     153.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHAIWKDHGDIEGALVSVKHIMISEMSALSPDIKANILKYINAS
                     GKYLRAGLCLYLAKEIEGKISQGKLYLAAAIETFHLATLIHDDVIDEADLRRNLKPLHR
                     VYSNKLAIYSGDYLLSYAGRLAAKGAQLLKIKETLEDEPPLSYQLVERILAGELAQLMN
                     QYNSQMTMKAYLKQIKGKTAFLFGIACQLGTWHPRLSQKELSAAYHFGIFLGMAFQISD
                     DLIDYQLKANQSGKPRLQDVQNGIYTAPLILGMAESKPIRQAVKNHKSLEWEQEELAML
                     YKQLEETQAFEATETLINNYLIKLNRACEILPLEHKEEFLIFIRRILARDF"
     gene            11091..11597
                     /locus_tag="GVO03_RS06275"
                     /old_locus_tag="ScFU1_12220"
     CDS             11091..11597
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060184.1"
                     /locus_tag="GVO03_RS06275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_12220"
                     /product="FMN-binding protein"
                     /protein_id="WP_003048496.1"
                     /transl_table=11
                     /translation="MKKKLLTGSLLVASLVMLAACGSKSDDKAAMSSEAKTEKVAKSTD
                     DKAMLKDGTYKAESAFDERGWKVVHTITVADGKITASNFGYENKDGKRKADDEEYNKNM
                     KAKSGVSSKEATEKLNSQLVEKQNIEDVEVVSGATHTSENFKKSTEALLKAAKEGKTDT
                     IDLGK"
     misc_feature    complement(11620..11638)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 24.96"
                     /tool="antismash"
     gene            11668..12720
                     /locus_tag="GVO03_RS06280"
                     /old_locus_tag="ScFU1_12230"
     CDS             11668..12720
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057524.1"
                     /locus_tag="GVO03_RS06280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_12230"
                     /product="FAD:protein FMN transferase"
                     /protein_id="WP_159305017.1"
                     /transl_table=11
                     /translation="MKFLKWLGAVLVCLCLGACQQEDAKQLAIIDTPLVRTEPLLHTVV
                     QLSIYHDHQEKTMAEAIRYIKDMEKLLSTNLEGSDVYRINHQAGQQAVKVDPRTYTIIK
                     AAKKMAETSHGKFDISIGAVTNLWRIGDDVARLPGKEEIEAALPYINYRHIHLNDKDRT
                     VFIEKGMTLELGAISKGYIADGVKTILKKHRVNTAIINLGGNVLGLGTSPKNPKEGWNV
                     GVQNPDQVRGDTVGTVHLKDQSIVTSGIYERFLEVNGKKYHHIIDPKTGYPVENNISGV
                     TVYTKTSLQGDELSTTLFLLGIKDGLKFINKMNQVEAVFIDKTKGVHLSKGLKDKFTLT
                     NKEYHIINEN"
     gene            12710..13660
                     /locus_tag="GVO03_RS06285"
                     /old_locus_tag="ScFU1_12240"
     CDS             12710..13660
                     /EC_number="2.5.1.74"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050631.1"
                     /locus_tag="GVO03_RS06285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_12240"
                     /product="1,4-dihydroxy-2-naphthoate polyprenyltransferase"
                     /protein_id="WP_003048500.1"
                     /transl_table=11
                     /translation="MKTKSLTLPIFLEFVELKTKVASVFPMIIGFAWSQWQYHQINVTN
                     SLLFALAVIAFDMCTTAINNTMDYHKAYDTAYQRNENVIGKHQLNVKHMTLIIYGLLAS
                     SCLISIILVIKTDLLLLPMGALCFLIGIFYTFGPFPLSRLPLGELFSGVTMGFGIFFLA
                     IYVQDPHQLFYSQWTSESISLTLKWMQVLKIALMSLPLVVLISNIMLANNICDYQQDLN
                     NRRYTLIHYLGEKNSRHLYVGLHSLAWLMFAFFIIWQWLPFFALLIFLAYPLSLKTLLI
                     FLKKQIKQETFIEAIKNFVLVSSIYVILLLILCLI"
     gene            complement(13725..14141)
                     /locus_tag="GVO03_RS06290"
                     /old_locus_tag="ScFU1_12250"
     CDS             complement(13725..14141)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048502.1"
                     /locus_tag="GVO03_RS06290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_12250"
                     /product="NusG domain II-containing protein"
                     /protein_id="WP_003048502.1"
                     /transl_table=11
                     /translation="MTYFKPYDYLLILVAIVISFIPLVVTSYYQSAATSSEALVAVVKI
                     NGKVADEFPLKKGGEHQEKTYYPQKGHYNIIEIDGERIRVKEDNSPDQIAVRTGWISQP
                     GQVSVCLPHQLIIEIQGSSSHSYQDNEDELILPL"
     misc_feature    14221..14234
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 23.48"
                     /tool="antismash"
     gene            complement(14241..15311)
                     /gene="xerS"
                     /locus_tag="GVO03_RS06295"
                     /old_locus_tag="ScFU1_12260"
     CDS             complement(14241..15311)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene="xerS"
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658412.1"
                     /locus_tag="GVO03_RS06295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_12260"
                     /product="tyrosine recombinase XerS"
                     /protein_id="WP_003048504.1"
                     /transl_table=11
                     /translation="MRRELLLEKIEAYKAIMPWYVLDYYQSKLAVPYSFTTLYEYLKEY
                     KRFFDWLIDADLTQAPKIADIDLSTLEHLTKKDLEAFVLYLRERPSLNTYSTKEGLSQT
                     TINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLASRAENIKQKLFL
                     GDETLAFLDYVDKEYEQKLSNRAKSSFRKNKERDLAIIALLLASGVRLSEAVNLDLKDI
                     NLNMMVIEVTRKGGKRDSVNVASFAKVYLEAYLAIRKNRYKAEKQDVAFFLTEYRGIPN
                     RMDASSIEKMVAKYSEGFKIRVTPHKLRHTLATRLYDATKSQVLVSHQLGHASTQVTDL
                     YTHIVNDEQKNALNKL"
     misc_feature    15427..15440
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.87"
                     /tool="antismash"
     gene            15648..16340
                     /locus_tag="GVO03_RS06300"
                     /old_locus_tag="ScFU1_12270"
     CDS             15648..16340
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184534.1"
                     /locus_tag="GVO03_RS06300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_12270"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_093998642.1"
                     /transl_table=11
                     /translation="MFSGDQLKAARLAKGMSQEALGQILNVNKMTISNWEKGKNTPNQK
                     HYDSLLSLFEVKADYFRPEHRLLVPFNQLLPTNKEKVISYSEQLLSQQSTLTMLPNKKR
                     QVYPYRVYESLSAGTGYSYFGDGNFDVVFYDEQLDYDFASWVFGDSMEPTYLNGEVVLI
                     KQDSFDYDGAIYAVEWDGQTYIKKVYREEDGLRLVSLNKKYSDKFAPYDEEPRIIGKII
                     ANFMPLEV"
     gene            complement(16530..18098)
                     /gene="ffh"
                     /locus_tag="GVO03_RS06305"
                     /old_locus_tag="ScFU1_12280"
     CDS             complement(16530..18098)
                     /GO_component="GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005048 - signal sequence binding
                     [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_process="GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /gene="ffh"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560729.1"
                     /locus_tag="GVO03_RS06305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_12280"
                     /product="signal recognition particle protein"
                     /protein_id="WP_093998643.1"
                     /transl_table=11
                     /translation="MAFESLTQRLQDVFKHIRGKKKLSESDVQEVTKEIRLALLEADVA
                     LPVVKTFIKRVRERAIGHDIIDTLDPTQQILKIVNEELTGILGAETAELEKSPKIPTII
                     MMVGLQGAGKTTFAGKLANKLIKEENARPLMIAADIYRPAAIDQLKTLGQQISVPVFEM
                     GTDHSAVEIVRRGLEQARENRNDYVLIDTAGRLQIDEKLMEELRDVKALANPNDILLVV
                     DSMIGQEAANVAEEFNRQLSITGVVLTKIDGDTRGGAALSVREITGKPIKFTGTGEKIT
                     DIETFHPDRMSSRILGMGDLLTLIEKASQEYDEKKSLELAEKMRENTFDFNDFIDQLNQ
                     VQNMGPMEDLLKMIPGMAGNPALSHIKVDDKQIARKRAIVSSMTPAERENPDLLNPSRR
                     RRIAAGSGNSFVEVNKFIKDFNQAKTMMQGIMSGDMSKMMKDMGINPNSFPKNMSGGMP
                     DMSSLERVMGQGGMPDLSSLGGDGDMDMSQLFGGGFKGKIGQFAMKQAMKRQANKIKKA
                     KKKRK"
     gene            complement(18113..18445)
                     /locus_tag="GVO03_RS06310"
                     /old_locus_tag="ScFU1_12290"
     CDS             complement(18113..18445)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637934.1"
                     /locus_tag="GVO03_RS06310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_12290"
                     /product="putative DNA-binding protein"
                     /protein_id="WP_003048510.1"
                     /transl_table=11
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIADEF
                     GVSRQAVYDNIKRTEKILETYEMKLHMYSDYIVRSEIFDEMMAHYPEDQYLQEKISILT
                     SIDNRE"
     gene            complement(18559..19257)
                     /locus_tag="GVO03_RS06315"
                     /old_locus_tag="ScFU1_12300"
     CDS             complement(18559..19257)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048513.1"
                     /locus_tag="GVO03_RS06315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ScFU1_12300"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_003048513.1"
                     /transl_table=11
                     /translation="MLPAYIKIHDAIKKDIDQGIWLIGSRLPSERDLAERFAVSRMTLR
                     QAVTLLVEEGILERRIGSGTYVASHRVQEKMRGTTSFTEIVRSQGRTPSSKLLTYQRQL
                     ASDTEVKELALDKTDHVIRMERIRYADNIPLVYEVASIPEKFIKRVKRNDITEHFFQTL
                     IANGYEIGKSQQTIYAKTASDRVASYLEVAKGHAILALTQVSYFTDGKPFEYVRSQYVG
                     DRFEFYLENK"
     misc_feature    20633..20648
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.99"
                     /tool="antismash"
ORIGIN
        1 cggcggtgac ggattctatt tttacgatgc ggcagcacct atcattgaca aatccactat
       61 tgacatgagc aaggtttatc tcaaatctcg ttatgataaa ggcgaagctg cttacctcaa
      121 ttgtcctatg accaaggaag aattcatggc ttttcatgaa gcactgacaa ctgcagaaga
      181 agcaccgctg aattcttttg aaaaagaaaa atactttgaa ggctgcatgc caatcgaagt
      241 catggccaaa cgtggcatta aaaccatgct ctacggtcca atgaaaccag tcggtttgga
      301 atacccagac gactacgaag gacctcgtga cggcgacttt aagacgccat acgccgttgt
      361 tcagctccgt caggacaatg ctgctggcag tctttataac atcgtcggct tccaaactca
      421 ccttaaatgg ggagaacaga aacgcgtttt ccaaatgatt ccaggtcttg aacatgctga
      481 atttgtccgc tacggtgtca tgcaccgcaa ttcctacatg gattcaccga atcttctgac
      541 ggaaaccttc caatctcgta gcaatccaaa ccttttcttt gctggtcaga tgaccggagt
      601 tgaaggttat gtcgaatcag ctgcttcagg cttagtagct ggtatcaatg ctgctcgtct
      661 tttcaagggt gaggaggaag tagtcttccc gcggacaaca gctatcggaa gccttcctta
      721 ctatgtaacc catacagaaa gcaagcattt ccaaccgatg aatgtcaatt ttgggatcat
      781 caaagaactt gaaggtccac ggattcgtga taagaaagaa cgttacgaag tcattgctaa
      841 tcgtgcctta gctgatttag aaaattgctt aaccgctctt taaaacttac aacagagttc
      901 ctctttagtc agttgactaa agagtttttt tgcgtattta tttgagtgtc caatgatgca
      961 aaagaatgca caaaaataca tgaattggct atggtcgcta gaagcaatag tatatcatga
     1021 atagtactca ttagttgatt cagttttgga gggtgtagca tgcagcaaca agtcgcagta
     1081 acagaaacag ttttacagaa ggacttttcc ttagtgaaac gcattcgctg taagagcgat
     1141 accaaaaaac ctacctgctt atcaaaattt tatgctcccc atcatatata gtagaaagag
     1201 accagcttcc tgtaattgtt gagccatgat ttcattataa atagtggtca ctcgacttgt
     1261 tggctcttct ccaacgtatc ttttatgaat atgaagggtt tgggctattt ttaggaaaat
     1321 agcggtgtcc aataaggctt gattcttctt aatcacatca ttgtcttctt tttggaaata
     1381 agctagaaag gttgcctgac taatcaaata ggaaccctaa ttcaattatt aaggtgcctt
     1441 agcccttcct gaatgagggg ttgtcgcact gcaagaggaa aagacttttg aaatggtata
     1501 gcgagacatt ttttctcctt atctataagc tactaaactt attatatcaa gattttagtc
     1561 tctaaagaaa aacaaatata aaataaatct ctctttcatg ttttgattcc atacgttttt
     1621 cgattatagg acggctgtta tcaatggttt tgccaataat ttcagttgta tcaggaataa
     1681 ttgaaatcag ctttcctacc gccccaaagg ctttgattat tttctttggc atttcttctc
     1741 tcctcgagtc atttctttta ctataacaaa atatctgaaa atagcatgca ataccttaca
     1801 aaactgtaag ttgcttgttt agcattgtaa ggttactctt agcctagtaa tgctaaacta
     1861 gacttatcaa aacgaagtta agaaaggaga ggaggctcat gaaacgatat atgaaagtgt
     1921 tatccttatt aggaattcct ctgatgataa tcctcagcat aggcatctat ggtattcaac
     1981 gttatggacc taactttaat ctgtatctat tcccacccag tgctcaaaaa tatggagaca
     2041 ttgccttaga acggttagat atgcttggct tgtatgctca aggtgaaaag tgggacaaga
     2101 cacgccaaga aacgcacaag gctcttaaaa aagcaaaatc ttacaaagaa gctcagcaaa
     2161 ttctccaaaa ggcagtgagc gtagcaggag gaaaacattc ctctttggtc agtaaaaaca
     2221 gtttccaaaa aagcttagtc gatcagcaga agcccgtagc acaggttgag ggcggtattc
     2281 tttatctaaa agtgcctgct attgaaggat tagctcccaa aactttgaca gcttacgcca
     2341 ataagttaaa cactcctctt acaaagaact ataagggagc aattgttgac ttgcgtggta
     2401 atactggtgg taatatgacc cctatgctta tcggattgtc gggacttcta ccggacggag
     2461 atttattcag ttttgaagat aagtaccgaa acaaacaggt cgtggagcta caaggcaaag
     2521 aactagtcaa tcaagatagt attgcgttag ataagccagt tgtcaaacaa gacatccctg
     2581 ttgcagtttt aatagatcac caaacagcct cttcaggaga aatgaccgca tttgcttttc
     2641 aaggcctaga aaataccctt ttctttggag agccaacagc aggttatacg acaggaaata
     2701 atgtcattcc cttatatgac ggtgcccttt tagttattac tagcagtcgc attatcaacc
     2761 gtcaaggaca agtttatgaa aataatccta ttttccctga cagaaatagc caagaccctc
     2821 ttgctgacgc caagcaatgg ttatcagaag taacgaaata agatataata gacacaaggt
     2881 tgtcaaaagg agtttaccat gttattagaa attaatcacc tcgaaaaagt gttccgcacg
     2941 cgcttttcaa aagaagaaac tagagcgcta caagatgtcg actttaaagt ggataagggc
     3001 gaatttattg cgattatggg agaatctggc tctggtaaaa caaccctctt aaatattctt
     3061 gctaccttag aaaaaccgac caatggatcc gtctgcttaa atggcattga tattactaaa
     3121 atcaaagaaa accgtctggc ggcatttcgt ctgcaaaacc tcggcttcgt cttccaagat
     3181 tttaatttac ttgatacctt atctgttcgg gataatattt tcttgccgct agtcttaaac
     3241 cgcagaccaa tcaaggaaat ggaggctcgc atcaaccaga ttgccccgca attacgtatt
     3301 gatacccttt tagataaacg accgtttgaa atttcaggcg ggcaaaaaca acgggtagct
     3361 atcgccagaa gcctgattac gaaaccacaa ttattacttg ctgacgaacc gacagcagcg
     3421 ctggattatc gtaattcaga agagttactc actctctttg aagagatcaa cagaagtggt
     3481 caaactattc taatggttac ccattcagcc aacgctgcca gccatgctaa ccgcgtctta
     3541 tttatcaaag atggccgcat tttccatcag atttaccgag gaaataaaaa taatttagac
     3601 tttaataaag atatttctat tgccatgaca ggccttttag gaggtgaata ggatgtttta
     3661 cctcaaatta gcttggaata accttagaaa ttctctaagc gtttcagctc cgtttttact
     3721 ggcgagtact gttttataca tgcttaattg cattgttcat attattctta tgagtcctat
     3781 ttcagaaaac atgaaacacg ggaaaatact cctcggttta ggcgccttta ttctgatcct
     3841 ctttgctctg attatggaag tttatagtta tcgcttttta ctcaatcaaa gaagccgaga
     3901 atttggtctc tataatatgc taggcatgaa taaaaagcaa gtcagctggg tttccaccct
     3961 tgaactcatt ttgatgtatt ttgtgacagt aggagtgggt agcctcttat cagctatttt
     4021 ttctcacctc ttttacttga tttttgtcaa tctggttcat tctaccaacc taaccttgca
     4081 atttcagata ggtgctttta tcttaacagc ctttatcttt gcttttattt tcggtttcct
     4141 agccttagtt ggcctgctta aaattggcaa aacctctcct ttaatgctct tcagagatag
     4201 tgaaaaagga gaaaaagaac ctcgcggcaa tttcctatta gcaggtcttt ccattatatc
     4261 tcttagtgtt ggttattata tttccttgac gtcttcgacg ttaacagctt ttgaaaccat
     4321 tattcgtttc tttatagccg ttatcattgt cattgttggt acctatcttt tttacatctc
     4381 ctttatgact tggtatttaa aacgccgtcg tcaaaataag acttattttt accagccaga
     4441 gcattttgtt agcacgtcac aaatgatttt taggatgaaa caaaatgctg tgggacttgc
     4501 taatatcacc attttagcag tgatggcatt tatttccatt gcgacaacaa ctgccttata
     4561 taccaataca gaggtaatga ctgaacaact ctttccaaga aatagtaaaa ttacctttga
     4621 taataatacc ttaacgaatc aagatgagat tttccaaaag gtggtcctag acaagattga
     4681 taaaaaagca tctgactttc tgatttataa ggataccatg ataacttttg aaatttctcg
     4741 agcctctaaa atcgtggtca ccaaaaagga tgtcatgcat cctaatatcg ctaaaattgg
     4801 tttcgtttat ctagttactc aagatgattt tcgttctttg ggaaataaac ttcctcagtt
     4861 aaagacaggt cagactgctt tctataaaca aaaaggggat agtcagttaa cagaaattga
     4921 gttattggga catcacttta agaatgtcct taatcttaaa acagttcaat tccctgcagt
     4981 agctaatacc tacaatcctg gagttttagt cgttagtgat aaaaccactt tagacaacgt
     5041 ccaagaaacc tttaaaaaga taactaatta cggctttgaa ccatcgataa ctgcctatgc
     5101 tgatctcact aaagaagaaa ttgctaagat tctagatgac aaaggaacca tcagtgataa
     5161 cggccaattt attggtaaca tagaaacaaa agaagactat cgtcttggcg tatatgccct
     5221 ctcaggaggt ttcctcttta caggtttctt actaggcttt agctttattc ttggcgcagc
     5281 cttaatcatt tactataaac aatactcaga aggacatgaa gatcaaaaat cgtacaagat
     5341 cttacaagaa gtaggtatga gtaaagacca agtcaaaaag actatcaatt cacaaattct
     5401 tttagttttc tttatgccaa ttgccttggc tgttctccat ttctgtgcag cgcttgtgat
     5461 gctcaagcaa atgctattgc tctttggtgt actagactca accctcattt atctggtcag
     5521 tgcaatcact attggtctca ttatttgcct ttattttatc atttataaga tgaccagcag
     5581 aacttattat cggattattg aaagataaga gaagtggcga tttttcgcca cttttttggt
     5641 agaataacag tatgacaaaa cacgacaaaa tttatattat cgaagatgat acaacaatct
     5701 tatctcttct tgacaatcac cttagccaag cctaccacgt taggactgtt actaatttta
     5761 gggatattaa acaagaagtg ctgacttacc aaccagatct tattttaatg gatattactc
     5821 ttccattttt caatggtttt tattggacga ctgaaatccg aaagcagtct accgttccta
     5881 ttatttttat ttccagcagc aatgatgaaa tggacacggt tatggccctc aatatgggag
     5941 gagatgattt tgtatctaaa cctttttcat taaccatttt agatgccaaa atagcagctt
     6001 ttttacggcg ttcccaacag tttaccagtg atgatattag ccttgatcag ttcaagcttc
     6061 attttgatgg taccttatcc aatggggaag atacggtcac tctttcaccg acagagcaca
     6121 aaatgctgac cattttgatg accagaaatc aagaaattgt ttccaaagag gaaatcttgg
     6181 aaaaactatg ggaaaacgat aactttattg atcataacac gctcaatgtt aacatgacac
     6241 gattacgtaa aaaaattggg agcattggtt tcgatcgtat tcatactgtt aggggagtgg
     6301 ggtacctcat caaatgattt tagctttttt aaaagaatac cgatcctttt accttcaata
     6361 tggtttgaca atactcattt actgggtagt tttctatttg taccatcttc ccatggcata
     6421 cttcacaaca gccaactgga tcgctttgac gattctagtc ttgaatagcc tttggcagta
     6481 ctatcagttc aaggaaaaaa taaaaatttt acaagaattt atttatgtaa aagaattaga
     6541 taccttaacc ttgcctagtg aaaaagccta ccgagcactc attgtcaaat taaaagaagc
     6601 agaagctgat catttattgc aacacatcaa taagcaaaaa aatatggaag ctctcatcaa
     6661 gatgtggtca catcaaatga aactcccctt atcagcactg tctttaatga ttcaaaccca
     6721 aaatacagat ttaaaagaat accagcagca agtctatcga ctagaacagt acctcaacag
     6781 tctcttgagc tatttaaaat tcaaacaaca tcaagatgat tttcgtttcc aagcagtctc
     6841 tgtcagagca gtggtttctt ctgtcatcaa gaaatccagc caactttgca ttgcaaaaaa
     6901 cattagtatg gaaatccagg gagattggca agtcaaaact gataagaagt ggcttagttt
     6961 tgccctaact caagtcattg ataatgccat caagtattcc aacaagggcg ggcatatcag
     7021 tatttccata aaagaaggta gtatgtcaat atcagataat ggtattggta tactaaaaga
     7081 agatttgcca cgactttttg acgagggctt tactggattt aatgggcacg aacaccaaaa
     7141 agccacagga ttagggctgt atatgaccaa acaaattttg gatcaattaa accttgatat
     7201 tcaaattgaa agtgtggtgg gagaaggcac caaagttata gtatttccac taaagaaata
     7261 gacaataaaa ccactagttg atactaatgg ttttatttac ataaatatag ttacgcaaac
     7321 agaaatcgtc agaaagtcca atcatccaat aaatcctgat gaaaccgttt tagaggggtt
     7381 acttttaaga gtaaataatt gcccgttaga ccaacaaaaa aacctgatat aataccacta
     7441 aaggataaaa taggaaggta attaagcacc aaccaagacc gagcaatgaa agcaaaaaca
     7501 agcagttggc caacattatg cataatacca ccaagggttg aaatgccgat gacgctcacg
     7561 cgttttggac ccaatgtttt taaggctaac atcactagaa aactcaatag tgttcccgaa
     7621 aaaccatata aaaaagtcga aaaggtccca cttagaaagg tagagagtaa cagttttaaa
     7681 aagataacct tggcactatc cattggtttt aaggtaaata tggccagtat agtgataaga
     7741 ttagctatcc caagcttagc tccaggtgca aaggcaaaag gagtaggaat gaagcgttca
     7801 tagaaggaaa tgaccactgc ctgagctgcc agcattgtaa taaataataa tttttgcgat
     7861 tgtttattca taatctttct ttctattctt tgtacacccc attttaacac aagataagat
     7921 aaaaaagaca aaataaaaga ttataatgtg actattcagt aaatatcatc ttgaatatca
     7981 ctagctagta tgatataata gcatgtgaaa tcgttaacgg aggacaacca tgacacataa
     8041 tatcgtcatt gtcggtgctg gctatgcagg aattgcttcc gctagatacc tagcaaaaac
     8101 attcaaaaaa cagcaagatg tgaccatcac gctgattgat aaaaattcat ttcagactta
     8161 tatgactgag ctacatgaag tagcagcagg ccgtgttgaa ccagaagcta ttaaatatga
     8221 cttgcaacgt attttcaaaa aatatcccaa agttcaatta gtcactgata aagtgcttgc
     8281 cattgactat gatcaacaac aagtcaaagc agaacaccat acccttgact tcgattactt
     8341 gattttagcc atgggaggag aagccaacga ttttggtact ccaggtgtta aagaacatgg
     8401 ctttagctta tggtctattg aagcagcaga aactttacat taccatattt tagatgcttg
     8461 ttaccatgcc atgaaagagc acgatgttgc taaacgcaga gccctattaa cctttactgt
     8521 catcggtgct ggtttcactg gtatcgaaat gattggggaa ttaattgact gggtaccaat
     8581 cctcgcgaaa caattcaagc tagatattaa tgacttctcc ttaaaagtag tagaagcaat
     8641 gccatctatc ttgaatatgg taacagaaaa agagcaaact aaggctcaaa aataccttat
     8701 taaaaaagga gttgaactga ttttagctga tggagtagca agtgttgaca aagatgctct
     8761 atacctcagc tcaggacgca aaattgatac ctacacatcc atttggacag caggggtaaa
     8821 agcaaacagt gataccagtg attttgacat tgaaaaagca cgtggaggtc gactcgttgc
     8881 taaccaatac atggagactt tggaacatcc aaatgtctat gttgcagggg acttggttta
     8941 ttacgaagat ggtagccaag ggggaaaacc aacaccgcaa attgttcagg ctgctgaaca
     9001 aactggtaaa acagctgctc aaaacattgc cgcaagtatc aagaaaactg aaaaagttag
     9061 ctacaagggc aagtatgacg gttttatggt ctccatagga tccaaatatg gggttgccta
     9121 tttgatggat aaattccact tatctggttt cctagctatg gctgtcaaac actttacaaa
     9181 cttactttat ttctttacta ttagtagttt ctttaatatt ggtgcctacc tcagacacga
     9241 gttctttgat attaaaaatg gtcgtaatat ttttggaagc aatttgtcaa gcaagggaaa
     9301 ccgtttgtgg ttagtcccat tacgtgtctt ttatggatca ttatggctat atgaaggtgt
     9361 taaaaaagcc tttggtttat ttggaacaga atcatggttt ggaaataagg ttgtctttcc
     9421 attcccgtgg cttcaaaaag cagcagaagt aacatctggt gcctcagagt ctggtggtga
     9481 tgctgttgcc aagggagcta gtgaaatggc caaacaagtt tttggtttga gttatactta
     9541 tggcgaagaa ccaatgcagg tactcaaatt aatgcctcac tggtttgaat ctctcatgaa
     9601 attcatgatg ccaaaccaag aagtcgctct gttcatgcaa aaaatgatga cttgcttaga
     9661 aatcgctatc ggtcttgcct taattgtagg tgcttttgtt tggttggtta gcgcagcaac
     9721 agcagcgtta gtcgtcatgt ttagcttatc tggtatgttc tattgggtaa acatctggtt
     9781 tattcctgta gccattgctt taatggcagg ggctggcaga agcttcggtc ttgattattg
     9841 gattatgcct tggttaggaa atcgactaga tcgatggatt tacggtaagc ctaaacacct
     9901 ttatctaaag aaaaatcatt aagttggcct gtctcgagaa taaattcaca ccagattgat
     9961 cttggaccaa ggcaaacaac aagtaaagga gaagctattt gtgatacatg ccatttggaa
    10021 agatcatggt gacatagaag gggcattagt cagtgttaaa cacatcatga tttctgaaat
    10081 gtcagcattg tctccagata ttaaagctaa cattttaaag tatatcaatg cttctggcaa
    10141 ataccttaga gcagggcttt gtctttatct agctaaggaa attgagggaa aaatctctca
    10201 aggtaaattg taccttgcag cagccattga aacctttcat ttggctactc ttatccatga
    10261 cgatgtgatt gatgaagcag atttgagacg aaatctcaaa ccgttgcatc gggtttattc
    10321 taacaaactt gccatttatt ctggtgatta cctcttgtcc tacgccggac gattggcagc
    10381 caaaggagcc caattattaa agattaagga aactttggaa gatgaaccac ctctttctta
    10441 tcagctagtt gaacgtattt tagctggcga attggcacaa ctcatgaatc aatacaatag
    10501 ccagatgacc atgaaagcct acctaaaaca gataaagggt aaaacagctt tcctctttgg
    10561 aatagcttgt caattgggta cctggcatcc tagattatca caaaaagagc taagtgcagc
    10621 ttatcacttt ggtatttttc taggaatggc ctttcaaata tcagacgact taattgatta
    10681 tcagcttaaa gctaatcagt ctggcaagcc tagactacaa gatgttcaaa atggcattta
    10741 cacggcccca cttattttgg gaatggcaga gtcaaagcct attaggcaag ctgtcaaaaa
    10801 ccacaaatct ttggaatggg agcaagaaga attagctatg ctttataaac agctagaaga
    10861 aacacaagct tttgaagcca ctgaaaccct gatcaataac tatttgataa aactcaatcg
    10921 agcctgtgag atattaccct tagaacacaa ggaggaattc ttgattttta tcagacgaat
    10981 cctcgctaga gacttttaac gaagcgtatg aaaggcttac ataaattgtt cgacctttca
    11041 cacaatttat ggtaaactaa ttaaaggaaa ttaaattgga ggtcttttta atgaaaaaga
    11101 aactgttaac aggttccctg ttagttgcat cacttgtcat gcttgctgca tgtggtagca
    11161 agtctgatga taaagcagca atgtcgtcag aagcaaaaac tgaaaaagtt gcaaaatcta
    11221 ctgatgataa agctatgctt aaagatggca cttataaagc tgagtcagca tttgatgaac
    11281 gcggttggaa agtggttcac accattacag ttgcagacgg taaaatcaca gcatcaaact
    11341 ttggatacga aaataaagat ggtaaacgaa aagctgatga cgaggaatac aacaaaaaca
    11401 tgaaggcaaa atcaggtgtt tcttcaaaag aagccactga aaaattaaac agccaacttg
    11461 ttgaaaaaca aaatattgaa gatgttgaag tggtttcagg agcaactcac acctcagaaa
    11521 acttcaaaaa atcaacagaa gctcttctca aagcagctaa agaaggtaaa acagatacca
    11581 ttgatttagg aaaataagtt actatcaaaa ccgaggggtt gaggttagcc ttagctcttt
    11641 ggttttttta tgataaaagg aggccttatg aaatttctca agtggctcgg agcagtatta
    11701 gtctgccttt gtttaggagc ttgtcagcag gaggatgcca aacagttagc catcattgat
    11761 acccctcttg ttcgaacaga gccattattg catacggttg tccagcttag catttaccat
    11821 gaccatcaag aaaaaaccat ggcagaagcc attcgttata ttaaagatat ggaaaaactc
    11881 ctatcaacta atctagaagg gtcagacgtc tatcgcatta accatcaggc tggtcaacaa
    11941 gcggtcaagg ttgatcctag aacctacacc attatcaaag cagccaaaaa aatggcagag
    12001 actagtcatg ggaaatttga tatttctatc ggagccgtta caaatttatg gcgtattgga
    12061 gatgatgttg ccagattacc aggcaaagag gaaatagaag cagcacttcc ttatattaac
    12121 taccgccata ttcatctcaa tgacaaagac aggactgtct ttattgagaa gggcatgacc
    12181 ttagaattag gagctatttc taaaggatat attgctgatg gtgtcaaaac cattttaaaa
    12241 aaacatcgtg tcaatactgc cattattaat cttggaggaa atgtcctagg ccttggtacc
    12301 tcaccaaaaa atcctaaaga aggttggaat gtgggtgtgc aaaatcctga tcaagttcga
    12361 ggagataccg ttggtaccgt tcatctcaaa gatcaatcga ttgttacttc aggtatttac
    12421 gagcgctttt tagaagttaa tggcaaaaaa taccatcata ttatagatcc caaaacaggc
    12481 tatcctgttg agaataacat ttctggtgtc actgtttata cgaaaacctc tttacaagga
    12541 gatgagctgt caaccacact ctttttatta ggaatcaaag atggccttaa attcatcaac
    12601 aaaatgaatc aggtagaagc tgtttttatt gataaaacaa agggggtgca tttaagcaag
    12661 gggctaaaag ataagtttac actaaccaat aaggagtatc atattattaa tgaaaactaa
    12721 atcacttacc ttacccattt ttttagaatt tgtcgaatta aaaacaaagg tagccagtgt
    12781 ttttccaatg attattggat ttgcttggag tcagtggcag tatcatcaga ttaatgtgac
    12841 taatagtttg ttatttgcct tagctgttat tgcttttgac atgtgcacaa cggctattaa
    12901 caatactatg gactatcata aagcttatga cacagcctat caacgcaacg aaaatgtcat
    12961 cggaaaacac caactcaatg tcaaacacat gacccttatc atttacggtc tgctggcttc
    13021 ttcttgcctg atttcaatca ttttagtcat taaaacagac cttttattgt tgccaatggg
    13081 tgccctctgt tttttaattg gcatttttta cacctttggg ccctttccac tttcacgtct
    13141 gcctcttggc gaactatttt caggggtcac tatgggcttt ggtatctttt tcttagcgat
    13201 ctatgttcag gatcctcatc agctctttta cagccagtgg actagcgaaa gtatctcact
    13261 cactttaaaa tggatgcaag tcttaaaaat tgccttgatg tcccttcctt tagtggttct
    13321 tatttccaat attatgcttg ctaataacat ttgtgattat cagcaagacc ttaacaacag
    13381 acgctatacc ttgatacact atttgggaga aaaaaatagc cgtcacctct atgtaggcct
    13441 tcacagctta gcttggttaa tgttcgcttt ctttatcatt tggcagtggc tgccattctt
    13501 tgctctctta atcttcctag cttatcctct tagccttaaa acgctcttga tctttttgaa
    13561 aaagcaaatc aaacaagaaa cctttattga agcaattaaa aattttgttt tagtgagcag
    13621 catctatgtc atcttgctcc tcattctttg cctcatttaa aaactacgct cagttatnna
    13681 taactgagcg tagtttttat aacataaagc gagactcaca aggattaaag cggaagaata
    13741 agttcatctt cgttatcttg ataagaatga ctacttgaac cctgaatttc aataatcagt
    13801 tgatggggca aacaaacaga cacctgaccc ggctgactaa tccagcctgt tctaactgca
    13861 atctgatcag ggctattatc ttccttaacc cgaatccgtt ctccgtcaat ttcaataata
    13921 ttgtaatgcc ctttttgagg ataataagtt ttttcctgat gttctcctcc cttttttaga
    13981 ggaaattcat cagctacttt gccattaatc ttgacaacag caactaaggc ctctgaagaa
    14041 gtagcagcag actgataata gctagtcacc acaagaggga taaaggaaat cacaattgct
    14101 actaaaatca gtagataatc gtaaggctta aaataagtca taataggttt aagttttcta
    14161 ttcacagtat tattttattt aaaattttcc aatttgtaaa ctattttaat cattaattta
    14221 cataattatt attatgtgaa ttaaagttta tttaaagcat ttttctgctc atcattgaca
    14281 atatgggtat aaagatccgt gacttgagta gaggcatggc ctaattgatg actaaccaaa
    14341 acctgagatt tagtagcatc atagagcctt gtcgctaacg tgtgtcgtaa tttatgggga
    14401 gtcacacgaa ttttaaatcc ctcagagtac ttagcaacca ttttttcaat actagaagcg
    14461 tccattcgat taggaatgcc acggtattcc gttaaaaaga aagcgacatc ttgtttttcg
    14521 gccttgtaac ggttcttgcg aatggccaga taagcttcta aatagacttt agcaaaactt
    14581 gctacattta ctgaatcacg tttcccacct ttacgagtga cttcaataac catcatattc
    14641 agattgatgt ctttgagatc aagattcacc gcttcagaca aacggacacc agaagcaagc
    14701 agtagggcga taatagccaa atccctctcc ttatttttac ggaaagaaga tttggcacga
    14761 ttagacaatt tttgctcata ttccttatct acatagtcta agaaagccag agtttcatct
    14821 cctaaaaata gtttttgttt aatattttct gctctggatg ctagggtttc ttttttcttt
    14881 tttgttgata cttttttcat aacattccga taaaaataag gctccccttg gtcattttcg
    14941 acctcttcag tcaagtattt gtaaagactt gatagggcgg acaaggtccg attaattgtg
    15001 gtttgagaaa gcccctcttt ggttgaatag gtgttgagag aaggtcgctc tcgcaaataa
    15061 agcacaaaag cctctaaatc cttcttagta aggtgctcca gagtgctcaa gtcaatatca
    15121 gcaatctttg gcgcctgagt caaatcagca tctatcagcc aatcaaaaaa gcgtttgtat
    15181 tcttttaaat actcatataa ggtggtaaag ctgtacggga cagctaattt ggattggtag
    15241 taatctaaaa cataccaagg catgatggcc ttgtaggctt caattttttc cagtaataac
    15301 tcacgtctca tgtcatcgtc cttatcaaat gtatcaatat tttttaaacc ctgtatctat
    15361 cttatagata atctcaaggt atcattatct aattatctat aagagaagtc tatcatacct
    15421 ttatccattt ttcaagaaaa ttacagtttt tcggaaagat gttgtaaaga aataaatggt
    15481 tctttacgaa atagacgaaa atttttgaaa tgatgttttc tgattataca ctttattaag
    15541 actatcatca aaaattttaa taattatttc aagggaaata cttgctttat tgtgtttact
    15601 ctgctatact ttagtaaagt tataacttta ctaaaggagt tgctatcatg ttttctggag
    15661 atcaattaaa agcggcacgc ttagcaaaag gcatgagcca agaagcatta ggccaaatac
    15721 taaatgttaa taaaatgact atttctaatt gggagaaagg taaaaatacc cccaatcaaa
    15781 aacattacga tagcttatta agtctttttg aggtgaaagc tgactatttc agacccgaac
    15841 atcgtttgtt agttccattt aatcaacttc ttcctaccaa taaagagaag gttattagct
    15901 attcagaaca gttactaagc caacaatcaa ctcttactat gcttcctaat aagaaacgcc
    15961 aagtttatcc ctatcgtgtt tatgaaagtc tgtcagctgg tacaggttat tcttattttg
    16021 gtgatggcaa tttcgacgtg gtcttttatg acgaacagtt agactatgat tttgcctctt
    16081 gggttttcgg tgattctatg gaaccaacct acctaaatgg tgaagttgtt ctcattaagc
    16141 aagatagctt tgactatgac ggtgccatct atgctgttga atgggatgga cagacctata
    16201 tcaagaaagt ttaccgtgaa gaagacggct tacggcttgt ttccttgaac aaaaaatatt
    16261 ctgataagtt tgccccctat gacgaagagc cacgtattat tggtaaaatt attgccaact
    16321 ttatgccact agaagtttaa tccatataat agaaaaagct aggtgtccta tcttagtgtt
    16381 tctcccactc atttagggtt ttagtcctct taacttcaaa aaatactcat atcgttaaat
    16441 tcccattaat aaaaagaaat agcttggagc cactcctacc tacttcacgc gatagagact
    16501 actgagctat ttcttttctg attgattgtt tatttccgtt ttttcttagc ctttttgatt
    16561 ttattggctt ggcgtttcat agcttgtttc atagcaaatt gaccaatctt ccccttgaaa
    16621 ccgccaccaa atagttgact catatccata tcgccatcgc cgccaaggga agataaatct
    16681 ggcataccac cttgtcccat cactctttct agagatgaca tatctggcat gccgcccgac
    16741 atatttttag ggaaactatt tggattaata cccatatctt tcatcatctt agacatatcg
    16801 cctgacataa tcccttgcat catagttttt gcttggttaa aatctttgat aaatttatta
    16861 acttccacaa agctgttacc tgatccggct gcaatacgac ggcggcggct aggatttagt
    16921 aagtctggat tttcacgttc agcaggagtc atcgaagaga cgatagcacg tttacgagca
    16981 atttgtttgt catcgacttt gatatgagat aaagcaggat taccagccat tcctggaatc
    17041 attttcaaaa ggtcttccat aggccccatg ttttgcacct gattcaactg atcaataaag
    17101 tcattgaaat caaaggtgtt ttcacgcatc ttttcagcta attctaaaga ttttttctca
    17161 tcatattctt ggctagcttt ttcgataagg gtaagtaagt cccccattcc caaaatacgg
    17221 ctggacatac ggtctgggtg gaaagtttca atatctgtaa ttttttcacc cgtacctgta
    17281 aatttaatcg gtttaccagt gatttcacga acagaaagtg ccgcaccacc acgggtatca
    17341 ccatcaattt tagttaaaac aaccccggta atacttaatt gacgattaaa ctcttcagca
    17401 acattagctg cttcttgacc aatcatgctg tcaacaacca aaagaatgtc attgggattg
    17461 gccaaagcct tgacatcgcg aagctcttcc attagctttt catcaatttg caaacgacca
    17521 gcagtatcga tcaagacata atcatttcgg ttttcacgag cctgttccaa acctcttcta
    17581 acaatctcaa cagcagagtg gtctgtcccc atctcaaaaa caggaacact aatttgttga
    17641 cccaatgttt ttaattgatc aatggccgct gggcgataaa tatcagcagc aatcatcaga
    17701 ggacgagcat tttcttcttt gattaatttg ttggccaatt ttcctgcaaa agttgtttta
    17761 ccagcccctt gcaagccgac catcataata atcgttggaa tttttggtga cttttcaagt
    17821 tccgcagttt ctgctcccaa gatacccgtt aattcttcat taacaatttt gagaatttgt
    17881 tgcgttgggt caagcgtgtc aataatgtca tgaccaatag cacgttcacg aacacgtttg
    17941 ataaaagtct ttaccacagg taaagcaaca tcggcttcta aaagagccag acgaatttct
    18001 ttcgtcactt cctgaacatc tgattccgat aattttttct taccacgaat atgtttaaag
    18061 acatcttgta aacgttgggt taagctttca aaagccatag tcgaaactcc tcttattctc
    18121 tattatcaat gctggttaaa atggaaattt tttcttgtag atactggtcc tcaggataat
    18181 gagccatcat ctcatcaaag atttcactac ggacgatata atctgaatac atgtgaagct
    18241 tcatctcata ggtctctaaa atcttttctg tacgtttaat attatcataa acagcctgac
    18301 gactaacacc aaattcatca gcgatttcag ctaaactata atcatcagca taatataatt
    18361 caatataatt catttgttta tctgtcaata aggctgcata aaactcaaaa agggcattca
    18421 ttcggtttgt tttttcaatt tccatagtct tcattttatc atattgttac cgtttttaac
    18481 agtagcaaat cagcaatctg cttctgactt ctgaggaaaa tgaaaagagg acggttgtca
    18541 ccccctcctg aaaaatcatt acttgttttc taaataaaat tcaaagcggt cgccaacata
    18601 ctgactacgg acgtactcaa aaggtttgcc gtctgtaaag taagacacct gagttagagc
    18661 caaaatggca tgtcctttag caacttccaa gtaggaagcc acacgatcgc tagctgtttt
    18721 agcataaatc gtctgttgac tcttcccaat ttcatagccg ttagctatta gcgtttggaa
    18781 aaagtgctct gtaatgtcat tacgcttgac acgtttaata aatttttctg ggattgaagc
    18841 aacctcataa accaaaggga tattatcagc ataacggata cgttccattc gaatcacatg
    18901 atctgttttg tctagagcaa gttctttcac ctctgtatca ctggccagtt gtcgttggta
    18961 agttagcaat ttagaagagg gggtgcgccc ctgagaacgt acaatttcag taaaacttgt
    19021 ggttcctctc atcttttcct gtacacgatg actagccaca taagtgccgc ttcctatcct
    19081 tctttcaaga atcccctctt ctacaagtaa ggtaaccgct tgacgtaacg tcatacgact
    19141 aactgcaaag cgttctgcca aatccctctc acttggcaac cgactaccaa taagccaaat
    19201 gccttgatca atatcttttt tgatggcgtc atgaatttta atataagctg gtagcatgcc
    19261 ttactcctta cgtcgattct tcttttattc tatcatattt ttcttaaaaa ctgcaaagca
    19321 aatagacaga tcttcctaaa tcaaagattg gatttacctt ttcgatggtt gctaattgcc
    19381 ctcaatacga attcactcaa cggtccttct aacgcctcaa ccacctccca ataggccacg
    19441 taatcattca accataaccc acctgatgga atcgcaatcc aatccgattc ttcattcaaa
    19501 gaagataatt taacaatttt tcatgagaca aacttagttt catcagcctt ctttgattcc
    19561 gattctgtca tcctaatatt tcttgtcttt ttaggaaaaa gtacctcata atgataacta
    19621 ggacggtaag tattatctat ttcttactta cccttccaat ccagtcataa tattttccta
    19681 aacgttgtac ctgaacctta tttcttatct gataatgagg cttttgattt agaagttctt
    19741 tggtgtatat ttttccctag tcttttattg taacacagct cccgatcatt tttaaaatcc
    19801 ctcagagaaa ttctaatgcc ttttcagtaa aaatatgcta caataagttg aaaactatca
    19861 accagatggt tggtatagaa tgaaaggatt acaatgactg aaatttcaat tttgaatgat
    19921 gttcaaaaaa ttatcgttct tgattatggt agccagtaca accagcttat tgctagacgt
    19981 attcgagaat tcggtgtttt ctccgaactg aaaagccata aaatcactgc tcaagaactt
    20041 cgtgagatta atccaattgg tatcgtttta tccggaggtc caaactctgt ttatgctgat
    20101 aatgcctttg gaattgaccc tgaaatcttt gaactaggta ttccgattct tggcatttgt
    20161 tatggtatgc aattaatcac tcacattttg ggtggtaaag ttgttcctgc aggacaagct
    20221 ggaaatcgtg agtacggtca atcaaccctt catcttcgtg ctaattcaaa attatttaca
    20281 ggtactcctg aagaacaact tgttttgatg agccatggcg atgctgttac ggaaattcca
    20341 gaaggctttc atcttgttgg agactcaaat gactgccctt atgctgctat ggaaaatact
    20401 cagaaaaagc tatatggtat ccaattccat ccagaagtta gacactctgt ctatggcaat
    20461 gatatcctca aaaactttgc agtagcaatc tgtggtgcac gtggtgattg gtcaatggat
    20521 aatttcattg aaatggaaat tgcaaaaatc cgcaaaacag ttggtgatcg taaagttctc
    20581 ctaggtctct ctggtggagt agattcttca gttgttggcg tccttcttca aaaagctatt
    20641 ggcgatcagt taacctgtat ctttgtagac catggccttc ttcgtaaaga tgaaggaaat
    20701 caggtgatgg gaatgcttgg aggcaaattt gggctaaata ttatccgagt agatgcttca
    20761 aaacgtttcc ttgatctcct tgcagatgtg gaagatcctg agaaaaaacg taaaattatc
    20821 ggtaatgaat ttgtatatgt ttttgacgat gaagctagca aattaaaagg tgttgacttc
    20881 cttgctcaag gaacactcta tactgatatt attgaatcag gaacagagac tgctcaaacc
    20941 atcaaatctc accacaatgt tggaggtctt cccgaagaca tgcagtttga gctgattga
//
