LOCUS       NZ_CP047020            26806 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Streptomyces broussonetiae strain T44 chromosome.
ACCESSION   NZ_CP047020
VERSION     NZ_CP047020.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces broussonetiae
  ORGANISM  Streptomyces broussonetiae
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9735779)
  AUTHORS   Mo,P.
  TITLE     Streptomyces sp. strain T44 isolated from rhizosphere soil of
            Broussonetia papyrifera
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9735779)
  AUTHORS   Mo,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2019) College of Life Science and Technology,
            Central South University of Forestry and Technology, No. 498,
            Shaoshan South Road, Changsha, Hunan 410004, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 25-OCT-2019
            Assembly Method                   :: HGAP v. 3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 12.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009796285.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 17:56:09
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,022
            CDSs (total)                      :: 8,931
            Genes (coding)                    :: 8,515
            CDSs (with protein)               :: 8,515
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 416
            CDSs (without protein)            :: 416
            Pseudo Genes (ambiguous residues) :: 0 of 416
            Pseudo Genes (frameshifted)       :: 171 of 416
            Pseudo Genes (incomplete)         :: 334 of 416
            Pseudo Genes (internal stop)      :: 29 of 416
            Pseudo Genes (multiple problems)  :: 110 of 416
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:31:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8232658
            Orig. end                         :: 8259464
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP047020.1.
            Bacteria and source DNA available from Zhao YL.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26806
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="29"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26806
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26806
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16806](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16806
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(181..1122)
                     /locus_tag="GQF42_RS37570"
                     /old_locus_tag="GQF42_37565"
     CDS             complement(181..1122)
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009339288.1"
                     /locus_tag="GQF42_RS37570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_37565"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_158927430.1"
                     /transl_table=11
                     /translation="MGAGHDHGHAHSHAPATGTAAAAYRGRLRIALGITLTIMVVEIVG
                     GLAADSLALIADAAHMATDAVGLGMALLAIHFANRPPSTNRTFGLARAEILAALANCLL
                     LLGVGGYVLYEAIERFVTPAQTRGGLMVVFGLIGLVANSISLTLLMRGQKESLNVRGAF
                     LEVAADALGSFAVLVSAVVILTTGWQGADPVASLVIGVMIVPRTVKLLRETLDVLLEAA
                     PKNVDMSEVRAHILALDGVEDVHDLHAWTITSGMPVLSAHVVVSSDVLSAIGHEKILHE
                     LQGCLGDHFDVEHCTFQLEPGGHAEHEARLCH"
     misc_feature    1209..1223
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     gene            complement(1271..2242)
                     /gene="galE"
                     /locus_tag="GQF42_RS37575"
                     /old_locus_tag="GQF42_37570"
     CDS             complement(1271..2242)
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (66-208). E-value:
                     2.5e-11. Score: 35.1. Matches aSDomain:
                     nrpspksdomains_GQF42_RS37575_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676194.1"
                     /locus_tag="GQF42_RS37575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_37570"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_158927432.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.2e-17, bitscore:
                     63.0, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.3e-10,
                     bitscore: 39.9, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWLITGGAGYIGAHVARAMAGAGESVVALDDLSAAVPARLPADV
                     PLVEGSTLDGDRLKRVLTQYGVTGVVHLAARKQVAESVAGPTRYYRENVGGLATLLDAV
                     AEAGVRRLLFSSSAAVYGNPDVDLITEDTPCAPVNPYGETKLAGEWLVRAAGRAHGIST
                     VCLRYFNVAGAAAPELADTGVFNIVPMVFDRLTRDEAPRIFGDDHPTPDGTCVRDYVHV
                     ADLAEAHLAAARRLADGDLSGDLTLNVGRGEGVSVRELITVIGEVTGDRREPVVEGRRP
                     GDAPRAVASAERAARELGWRARRDVREMVASAWQGWQLHHGG"
     aSDomain        complement(1619..2044)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GQF42_RS37575_NAD_binding_4.1"
                     /evalue="2.50E-11"
                     /label="GQF42_RS37575_NAD_binding_4.1"
                     /locus_tag="GQF42_RS37575"
                     /protein_end="208"
                     /protein_start="66"
                     /score="35.1"
                     /tool="antismash"
                     /translation="VTGVVHLAARKQVAESVAGPTRYYRENVGGLATLLDAVAEAGVRR
                     LLFSSSAAVYGNPDVDLITEDTPCAPVNPYGETKLAGEWLVRAAGRAHGISTVCLRYFN
                     VAGAAAPELADTGVFNIVPMVFDRLTRDEAPRIFGDDH"
     CDS_motif       complement(2171..2239)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GQF42_RS37575_0001"
                     /evalue="6.40E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="GQF42_RS37575"
                     /protein_end="24"
                     /protein_start="1"
                     /score="18.8"
                     /tool="antismash"
                     /translation="TWLITGGAGYIGAHVARAMAGAG"
     gene            2602..4407
                     /locus_tag="GQF42_RS37580"
                     /old_locus_tag="GQF42_37575"
     CDS             2602..4407
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996269.1"
                     /locus_tag="GQF42_RS37580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_37575"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_158927434.1"
                     /transl_table=11
                     /translation="MSTAIVTGQPVPGSSLENDLRSLGFDVRVAEDASEAETLLAAAPA
                     GERVALVDAGFVGHQHALRLGLTDPRFELSAVPGAVTAQPAARQALTRAVARETFPGGG
                     TALAVDSLTDRIVTALDADGSEVHRPELGSLVAAVPADPQARNEARQAVAAVDEEAVRL
                     KSAVKSRDGFFTTFFISPYSRYIARWCARRGLTPNQVTTASLLTALIAAGCAATGTRAG
                     FVAAGVLLIASFVLDCTDGQLARYALKYSTLGAWLDATFDRAKEYAYYAGLALGAARGG
                     GHDDVWALALGAMILQTCRHVVDFSFNEANHDATANTSPTAALSDRLDGVGWTVWARRM
                     IVLPIGERWALIAVLTAATTPRITFYVLLVGCAVAATYTTAGRVLRSLTRKARRTDRAA
                     GALADLADSGPLTEVVQRVLERGLPGLAVPAVALAGGAAVLACAAVTDFGSALPVIGAL
                     VYVLTSAFAVARPLKGALDWLVPPFFRAAEYGTVLILAARADVNGALPAAFGLVAAVAY
                     HHYDTVYRIRGNAGAPPAWLVRVIGGHDGRTLLVAVLAAVLTAAQFTVALTVLAVAVAL
                     VVLAESIRFWVSAGAPAVHDEGESA"
     gene            4404..5156
                     /locus_tag="GQF42_RS37585"
                     /old_locus_tag="GQF42_37580"
     CDS             4404..5156
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983099.1"
                     /locus_tag="GQF42_RS37585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_37580"
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="WP_158927436.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 7.4e-10, bitscore:
                     38.4, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDTLPKALVPVGPAGIEGEPTVLDLTLG
                     NFAEIGLTEVAVIVGYRKEAVYARKAALEAKYGLKLTLIDNDKAEEWNNAYSLWCGRDA
                     LKDGVILANGDTVHPVSVEKTLLAARGEGKRIILALDTVKSLADEEMKVVVDPEKGMTK
                     ITKLMDPAEATGEYIGVTLIEGDAAPDLADALKAVWETDPQQFYEHGYQELVNRGFRID
                     VAPIGDVQWVEIDNHDDLAKGREIACRY"
     gene            5144..6205
                     /locus_tag="GQF42_RS37590"
                     /old_locus_tag="GQF42_37585"
     CDS             5144..6205
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007494151.1"
                     /locus_tag="GQF42_RS37590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_37585"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_158927438.1"
                     /sec_met_domain="Fe-ADH (E-value: 5.7e-22, bitscore: 77.0,
                     seeds: 218, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 8.8e-08, bitscore:
                     30.6, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLLTRLIPSPVVVDIRPGALDDLAGVLADERIAQSGRLAVAVSG
                     GSGAKLRERIAPSLPGASWYEVGGGTLDDAIRLAGEMKSGHYDAVVGLGGGKIIDCAKF
                     AAARVGLPLVAVPTNLAHDGLCSPVATLDNDAGRGSYGVPNPIAVVIDLDVIREAPARF
                     VRAGIGDAISNINAVADWELSNRVTGEKVDGLAAAVARQAGEAVLRHPGGIGDNDFLQV
                     LAEALVLSGISMSISGDSRPSSGSCHEINHAFDLLFPKRAAAHGEQCGLGAAFATYLRG
                     AHEEAAHTAEVLRRHGLPVLPEEIGFTVDEFVRAVEFAPETRPGRYTIIEHLDLKPNQI
                     KDIYADYVKAIGS"
     gene            6183..6962
                     /locus_tag="GQF42_RS37595"
                     /old_locus_tag="GQF42_37590"
     CDS             6183..6962
                     /EC_number="2.7.8.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049651.1"
                     /locus_tag="GQF42_RS37595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_37590"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_158927440.1"
                     /transl_table=11
                     /translation="MSRPSVAELRPVVHPAGVKDRRSGEHWMGRLYMREVSLRVDRYLV
                     NTRVTPNQLTYLMTVFGVLAAPALLVPGIWGAVLGVVCVQLYLLLDCVDGEIARWKKQY
                     SLNGVYLDRVGAYLTDAAVLVGFGLRAADLWGGGRVDWLWAFLGTLAALGAILIKAETD
                     LVGVARHQAGKPPVQEAAAEMRSSGMKLARRAAAALKFHRLILGIEASLLILVLAVVDH
                     VRGDLFFSRLGVAVLAGIALLQTLLHLVSILASSRLK"
     gene            6995..7840
                     /locus_tag="GQF42_RS37600"
                     /old_locus_tag="GQF42_37595"
     CDS             6995..7840
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009339265.1"
                     /locus_tag="GQF42_RS37600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_37595"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_158931054.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.5e-10,
                     bitscore: 40.2, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGNRPDELKALIDSVAKQDGDRIEVVVVGNGSPVPDVPEGVRTIE
                     LAENLGIPGGRNVGIEAFGPGGRDVDILLFLDDDGLLARHDTAQLCREAFEADPELGII
                     SFRIADPDTGETQRRHVPRLRASDPMRSSRVTTFLGGANAVRTRVFAEAGTLPDEFFYA
                     HEETDLAWRALDAGWMIDYRSDMVLYHPTTAPSRHAVYHRMVARNRVWLARRNLPVLLV
                     PVYLGVWLLLTLLRRPSAPALKAWFGGFKEGWTTSCGPRRPMRWRTVWRLTRLGRPPVI
                     "
     gene            7900..8832
                     /locus_tag="GQF42_RS37605"
                     /old_locus_tag="GQF42_37600"
     CDS             7900..8832
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994380.1"
                     /locus_tag="GQF42_RS37605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_37600"
                     /product="ABC transporter permease"
                     /protein_id="WP_158927442.1"
                     /transl_table=11
                     /translation="MSHTTHDGGAAAVNAIPSPDEGLTAAQLAAKYGLAVSGARPSLAE
                     YVRQLWGRRHFILAFSQAKLTAQYSQAKLGQLWQVATPLLNAGVYYFIFGVILHASRGL
                     SQDVYIPFLVTGVFVFTFTQSSIMSGVRAISGNLGLVRALHFPRASLPISFSLQQLQQL
                     LFSMIVMFVVAVGFGSYPSPSWLLIVPVLLLQFLFNTGLALIVARMGAKTPDLAQLMPF
                     ILRTWMYTSGVMFSISKIMEGRSELAVRLLQVNPAAVYMDLMRYALIDGYGAANLPPHV
                     WAIALFWAVAAFAGGFVYFWKAEERYGRG"
     gene            8852..9640
                     /locus_tag="GQF42_RS37610"
                     /old_locus_tag="GQF42_37605"
     CDS             8852..9640
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676201.1"
                     /locus_tag="GQF42_RS37610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_37605"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_158931056.1"
                     /transl_table=11
                     /translation="MPGQNTGERRPTVIADDVHIVYRVNGARTGKGSATAALSRILKRG
                     SDDAARGVRKVHAVRGVSFVAYRGEAVGLIGSNGSGKSTLLRAIAGLLPAERGKVYTEG
                     QPSLLGVNAALMNDLTGERNVILGGLAMGMSREQVKERYQEIVDFSGINEKGDFITLPM
                     RTYSSGMAARLRFSIAAAKDHDVLMIDEALATGDRKFQMRSEERIRELRKEAGTVFLVS
                     HNNKSIRDTCDRVLWLERGELRMDGPTEEVLKEYEKFTGK"
     gene            10001..10897
                     /gene="hpnC"
                     /locus_tag="GQF42_RS37615"
                     /old_locus_tag="GQF42_37610"
     CDS             10001..10897
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019985319.1"
                     /locus_tag="GQF42_RS37615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_37610"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_158927444.1"
                     /sec_met_domain="phytoene_synt (E-value: 7e-37, bitscore:
                     126.1, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1e-38,
                     bitscore: 132.3, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATEAAPALQRATLDKAASENFPVAPFFLPRAWRDDLMAVYGFA
                     RLVDDIGDGDLAPGGADARALGVSPDGAEDRLVLLDAFETDLRRVFDGSPHHPLLRRLQ
                     PTVRCRGLTPEPFLGLIAANRQDQLVSRYETYDDLLAYCELSANPVGRLVLGVTGTATP
                     ERIRLSDAICTALQIVEHLQDVAEDLARDRIYLPAVDMKRFHVQEADLGGKSAGASVRA
                     LVAYEAQRARDLLNEGAPLVGSVHGRLKLLLAGFVAGGRAAIRAIAAAEYDVLPGPPRP
                     GKVQLLREAGVILREEG"
     gene            10894..11856
                     /gene="hpnD"
                     /locus_tag="GQF42_RS37620"
                     /old_locus_tag="GQF42_37615"
     CDS             10894..11856
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972236.1"
                     /locus_tag="GQF42_RS37620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_37615"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_199272932.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.7e-56, bitscore:
                     190.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 7.4e-70,
                     bitscore: 234.6, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTVESPSHVSAPVLAAYSYCEAVTGQQARNFAYGIRLLPTPKR
                     RAMSALYAFSRRVDDIGDGDLPGETKLTRLEDTRALLARVHEGQVEEDDTDPVAVALAH
                     AATAFPIPLGGLDELIDGVQMDLRGETYETWDDLKVYCRCVAGAIGRLSLGVFGTERGA
                     RGAERAAEYADTLGLALQLTNILRDVREDAQGGRTYLPADDLAKFGCSAGFDGPTPPEG
                     SDFAGLVHFEVRRARALFAEGYRLLPMLDRRSGACVAAMAGIYRRLLDRIERDPEAVLR
                     GRVSLPGREKAYVAVRGLSGLDARNVTRHTAPRSVRRRA"
     gene            11856..12098
                     /locus_tag="GQF42_RS47835"
     CDS             11856..12098
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039420.4"
                     /locus_tag="GQF42_RS47835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6380 family protein"
                     /protein_id="WP_376000812.1"
                     /transl_table=11
                     /translation="MDLTEPGDMRQATLHGGVASQTATADRAPFDQHARAPKARGAVPA
                     MRLPLRGCDEPRGTRGRPTAQHGTPRGALARKDAR"
     gene            12095..13531
                     /gene="hpnE"
                     /locus_tag="GQF42_RS37625"
                     /old_locus_tag="GQF42_37620"
     CDS             12095..13531
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018546810.1"
                     /locus_tag="GQF42_RS37625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_37620"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_158927448.1"
                     /transl_table=11
                     /translation="MTDRSRPAQAHADTAGAEGAAGRSAVVVGGGLAGITAALALADAG
                     VRVTLLEGRPRLGGLAFSFQRGELTVDNGQHVYLRCCTAYRWFLDRIQGAALAPLQDRL
                     DVPVVDVAKPEGRRLGRIRRDPLPVPLHLGRSLAAYPHLSLAERAAVGRAALALKGLDL
                     ADPTLDTQDFGSWLAAHGQSARAIEALWDLVGVATLNAVAGDASLGLAAMVFKTGLLSY
                     PGAADIGWARVPLGELHDRLARKALDSAGVRTEVRTRVTSVSTNENGTWSVQVPGETLQ
                     TDAVVLAVPQQETHDLLPTGALDAPERLLGIPAAPILNVHIVYDRKVLARPFFAALGTP
                     VQWVFDRTDSSGLAAGQYLALSQSAAHDDIDAPVATLRERYLPELERLIPGTRGAVVKD
                     FFVTRERTATFAPVPGVGRLRPGARTKAPGLYLAGAWTATGWPATMESAVRSGVSAADA
                     ALSALGRPRPRRLFAFEEAA"
     gene            13600..14664
                     /locus_tag="GQF42_RS37630"
                     /old_locus_tag="GQF42_37625"
     CDS             13600..14664
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972234.1"
                     /locus_tag="GQF42_RS37630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_37625"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_199273143.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 7.9e-57, bitscore:
                     191.5, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPAPTPARRTAVDVTALLERGRTLATPVLRSAVDRLAPPMDTVA
                     AYHFGWIDAAGNPAAGDGGKAVRPALAVLSAEVTGAAPEVGVPGAVAVELVHNFSLLHD
                     DLMDGDEQRRHRDTVWKVHGPAQAILVGDALFALANEVLLELGTVEAGRATRRLTAASR
                     ALIDGQAQDISYEHRDRVSVEECLEMEGNKTGALLAASSSIGAVLGGADDATADALEKY
                     GYHLGLAFQAVDDLLGIWGDPEATGKQTWSDLRQRKKSLPVVAALAAGGSASEKLGEIL
                     AADAKSSDFENFSEEEFAARAALIEEAGGREWTADEARRQHTIAIEALDVVHMPGRVRD
                     AFTALADFVVVRKR"
     gene            14782..16806
                     /gene="shc"
                     /locus_tag="GQF42_RS37635"
                     /old_locus_tag="GQF42_37630"
     CDS             14782..16806
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0016866 - intramolecular transferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019985322.1"
                     /locus_tag="GQF42_RS37635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_37630"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_158927452.1"
                     /sec_met_domain="T2TS (E-value: 1.4e-152, bitscore: 508.1,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGSTGATLPSHAAAASDTTLSTPEAAGVHQAATRAARRAT
                     DFLLARQDAQGWWKGDLETNVTMDAEDLLLRQFLGIRDEKTTQAAAMFIRSEQREDGTW
                     ASFYKGPGELSTTIEAYVALRLAGDAPDEAHMAKASAWIRERGGIAASRVFTRIWLALF
                     GWWKWEDLPELPPELIYFPTWMPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDEL
                     HTDPASPNPPRPLAPVTSWEGAFQRLDKGLHQLRKVVPRRLRRAAMDSAARWIIERQEN
                     DGCWGGIQPPAVYSVIALHLLGYDLEHPVMREGIASLDRFAVWREDGSRMIEACQSPVW
                     DTCLAAIALVDAGLPADHPQLVKAADWMLGEEIVRPGDWAVKRPGLPPGGWAFEFHNDN
                     YPDIDDTAEVALALRRVGHHDPERMDKAIARAVRWNLGMQSKNGAWGAFDVDNTSPFPN
                     RLPFCDFGEVIDPPSADVTAHVVEMLAAEGLAHDPRTRRGIDWLLAEQESNGSWFGRWG
                     VNYIYGTGSVVPALTAAGLPGSHPAIRRAVAWLESIQNDDGGWGEDLRSYKYVKEWSGR
                     GASTASQTAWALMALLAAGEQDSKAVERGVQWLADTQREDGSWDEPYFTGTGFPWDFSI
                     NYHLYRQVFPLTALGRYLHGDPFERGLLARKPHSEVKVG"
     gene            16808..17449
                     /locus_tag="GQF42_RS37640"
                     /old_locus_tag="GQF42_37635"
     CDS             16808..17449
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431357.1"
                     /locus_tag="GQF42_RS37640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_37635"
                     /product="1-hydroxy-2-methyl-2-butenyl 4-diphosphate
                     reductase"
                     /protein_id="WP_158927453.1"
                     /transl_table=11
                     /translation="MSTQPAPAPLLIACALGIEHLALRTGDRHGADGPVTFLRTGMGPR
                     AAERSVTRRLAVPALAEAAVLATGFCAGLAPGMHPGDLVVAEETRDPRGSVPCVGTELL
                     VKELVRLLPGRTVHTGPLTGSDHVVRGPERAQLLARGAIAVDMESAATLLAAARTGERP
                     VAAVRVVVDAPEHELVRIGTVRGGISAFRVLRSVLPAFFEWHRSSLLPRR"
     gene            17455..18477
                     /gene="hpnH"
                     /locus_tag="GQF42_RS37645"
                     /old_locus_tag="GQF42_37640"
     CDS             17455..18477
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386169.1"
                     /locus_tag="GQF42_RS37645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_37640"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_158927454.1"
                     /sec_met_domain="PF04055 (E-value: 1.6e-17, bitscore: 63.4,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 2.6e-08, bitscore: 32.6,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQTIKVATYLFEQKLRKRDKFALLVELEPLFACNLKCEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIDEIVRQLVAKKKFVF
                     LCTNALLMRKKMDKFKPSPYFAWAVHVDGLRERHDASVAKEGTFDEAVEAIKEAKRRGF
                     RVTTNSTFFNTDTPQTVIDVLNFLNDDLKVDEMMLSPAYAYDKAPDQEHFLGVQQTREL
                     FKKAFSGGNRAKWRLNQSPLFLDFLEGKVDFPCTAWAIPSYSLFGWQKPCYLMSDGYVP
                     TYRQLLEETDWDQYGRGKDPRCDNCMAHCGYEPTAVLATMGSLKESLRAMRETVSGNRE
                     "
     gene            18482..19609
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="GQF42_RS37650"
                     /old_locus_tag="GQF42_37645"
     CDS             18482..19609
                     /EC_number="1.17.7.1"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity (ferredoxin) [Evidence IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031167.1"
                     /locus_tag="GQF42_RS37650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_37645"
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_158927455.1"
                     /transl_table=11
                     /translation="MSAVPLGVPEVPARPVAPRRQSRQISVGPVAVGGGAPVSVQSMTT
                     TRTSDIGPTLQQIAELTASGCQIVRVACPTQDDADALATIAQKSQIPVIADIHFQPKYV
                     FAAIEAGCAAVRVNPGNIKKFDDQVKQIARAAGEHGTPIRIGVNAGSLDRRLLQKYGRA
                     TPEALVESALWEASLFEEHDFRDIKISVKHNDPVVMIEAYRQLAEQCDYPLHLGVTEAG
                     PAFQGTIKSAVAFGALLSRGIGDTIRVSLSAPPAEEVKVGIQILQSLGLRQRRLEIVSC
                     PSCGRAQVDVYKLAEEVTAGLDGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQI
                     FVKGEVVKTVPESKIVETLIEEAAKIAERTSPADK"
     gene            19644..21692
                     /gene="dxs"
                     /locus_tag="GQF42_RS37655"
                     /old_locus_tag="GQF42_37650"
     CDS             19644..21692
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012999180.1"
                     /locus_tag="GQF42_RS37655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_37650"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_233273618.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 3.3e-111,
                     bitscore: 369.9, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.9e-06, bitscore:
                     25.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTILENIRGPRDLKALSEAELGELSHEIREFLVQAVSRTGGHLGP
                     NLGVVELSIALHRVFESPADRILWDTGHQSYVHKLLTGRQDFSKLRGKGGLSGYPSREE
                     SEHDVIENSHASTALGWADGLAKANQVLGEKSHVVAVIGDGALTGGMAWEALNNIAAAK
                     DRPLIIVVNDNERSYAPTIGGLANHLAALRTTDGYEKVLAWGKDVLLRTPVVGNTIYES
                     LHGAKKGFKDAFAPQGMFEDLGLKYVGPIDGHDLKAVESALRRAKRFHGPVLVHCLTEK
                     GRGYEPALAHEEDHFHSVGVMDPLTCEPLAPSGGPSWTSVFADEIVRIGEERDDVVAIT
                     AAMLHPVGLAKFAERFPERVWDVGIAEQHAAVSAAGLATGGLHPVVAVYATFLNRAFDQ
                     LLMDVALHRCGVTFVLDRAGVTGADGASHNGMWDMSVLQVVPGLRIAAPRDAGQLGAQL
                     REAVAVDDAPTLIRFPKESVGPDIPAVAQVGGMDVLHRGERPEVLLVAVGVMAPVCLQA
                     ADLLQARGIDCTVVDPRWVKPVDPALPGLAAEHRLVAVVEDNSRAAGVGSAVALALGDA
                     DVDVPVRRFGIPEQFLAHAKRGEVLADIGLTPVEIAGRIGASLAVRDAAGAAAGSGQGR
                     TAAVAPSGTVAPPNSRLRSSGEVPPARRQPHADRAPALLRSADKEKE"
     gene            21689..23074
                     /locus_tag="GQF42_RS37660"
                     /old_locus_tag="GQF42_37655"
     CDS             21689..23074
                     /NRPS_PKS="Domain: Aminotran_3 (41-363). E-value: 1.9e-85.
                     Score: 278.8. Matches aSDomain:
                     nrpspksdomains_GQF42_RS37660_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007494124.1"
                     /locus_tag="GQF42_RS37660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_37655"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_158927456.1"
                     /sec_met_domain="Aminotran_3 (E-value: 8.8e-83, bitscore:
                     277.2, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTEFDLGATLAERGAERYELHTKYLNPQLPRMLHTIGFDKVYER
                     AEGAHFWDAEGNDYLDMLAGFGVMGLGRHHPVVRRALHDVLDLDLADLTRFDCQPLPGL
                     LAERLLVHSPHLDRVFFGNSGTEAVETALKFARYATGKPRVLYCDHAFHGLTTGSLSVN
                     GEDGFRDGFAPLLPDTAVPLGDLDALARELSKGDVAALIVEPIQGKGVHEAPPGYLRAA
                     QDLLHRHKALLIADEVQTGLGRTGDFYAYQYEDGVEPDLVCVAKALSGGYVPVGATLGK
                     DWIFKKVYSSMDRVLVHSASFGSNAQAMACGLAVLSVMENEQIVAGVRTTGELLRSRLA
                     ALIEKYELLADVRGRGLMIGIEFGKPSSLKLRSRWTVLQAARKGLFAQMVVVPLLQRHR
                     ILTQVSGDHLEVIKLIPPLVLDTADVDRFVDAFTAVMDDAHSGGGLMWDFGKTLIKQAV
                     ANR"
     aSDomain        21812..22777
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GQF42_RS37660_Aminotran_3.1"
                     /evalue="1.90E-85"
                     /label="GQF42_RS37660_Aminotran_3.1"
                     /locus_tag="GQF42_RS37660"
                     /protein_end="363"
                     /protein_start="41"
                     /score="278.8"
                     /tool="antismash"
                     /translation="VYERAEGAHFWDAEGNDYLDMLAGFGVMGLGRHHPVVRRALHDVL
                     DLDLADLTRFDCQPLPGLLAERLLVHSPHLDRVFFGNSGTEAVETALKFARYATGKPRV
                     LYCDHAFHGLTTGSLSVNGEDGFRDGFAPLLPDTAVPLGDLDALARELSKGDVAALIVE
                     PIQGKGVHEAPPGYLRAAQDLLHRHKALLIADEVQTGLGRTGDFYAYQYEDGVEPDLVC
                     VAKALSGGYVPVGATLGKDWIFKKVYSSMDRVLVHSASFGSNAQAMACGLAVLSVMENE
                     QIVAGVRTTGELLRSRLAALIEKYELLADVRGRGLMIGIEF"
     misc_feature    23381..23390
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.92"
                     /tool="antismash"
     gene            23540..24163
                     /locus_tag="GQF42_RS37665"
                     /old_locus_tag="GQF42_37660"
     CDS             23540..24163
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676212.1"
                     /locus_tag="GQF42_RS37665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_37660"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_158927457.1"
                     /transl_table=11
                     /translation="MNASDAAPPAEPGDALPAVAPQLRALRRRAGLTLEAAARAAGLSP
                     AHLSRLETGQRQPSLPMLLALARIYGTTVSDLLGETVADRDAIVRAGDMEPTRAGGWTY
                     FQAGASGRGMQALRVQAPYGAQGDIVRVHPGEEWLYVLKGRLRLRLGDTAHLLAPGDSA
                     HFDSLTPHRLAAEDHDGVELLFVHTLLQSPTTALCLGPLTGELP"
     gene            24160..24282
                     /locus_tag="GQF42_RS37670"
                     /old_locus_tag="GQF42_37665"
     CDS             24160..24282
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676213.1"
                     /locus_tag="GQF42_RS37670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_37665"
                     /product="DUF6126 family protein"
                     /protein_id="WP_158927458.1"
                     /transl_table=11
                     /translation="MSNYETKFPRSLWIRLIIYIAVGHLLAAFLYLLFALGGKG"
     gene            complement(24302..25099)
                     /locus_tag="GQF42_RS37675"
                     /old_locus_tag="GQF42_37670"
     CDS             complement(24302..25099)
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069689.1"
                     /locus_tag="GQF42_RS37675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_37670"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_158927460.1"
                     /transl_table=11
                     /translation="MTQQVPSTEPELAGVRNFRDVGGLPTTDGRRVRHGVLFRSGHLAH
                     ATEDDAAFLASLGLHTIFDFRNAADQRLEGPDVALPGVRNMNLPLSDPADGAEFWKMVR
                     DGDLDQLRGILADGKGAARMVASYRTIVKERTAEHSRVLRSLVEDSVPALMHCAAGKDR
                     AGISIAVTLLALGVEREAIVADYLESNAKHRRYKVRRSGSADSAYTPEVMELLSPLFDA
                     RAEYLEAAFESIEDTWGGVDPYLQQALGLTPIDRDRLRERLLD"
     gene            complement(25296..26762)
                     /gene="ltrA"
                     /locus_tag="GQF42_RS37680"
                     /old_locus_tag="GQF42_37675"
     CDS             complement(25296..26762)
                     /EC_number="2.7.7.49"
                     /GO_function="GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ltrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007449091.1"
                     /locus_tag="GQF42_RS37680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_37675"
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="WP_158927462.1"
                     /transl_table=11
                     /translation="MPKDALLNSSAPGALMGSHQRVSGMQAKLHRWAAADPGRRFDDLF
                     NLVYDPATLLVAFERVAGNKGANTPGVDGLTAVNVERDIGPYGFLEGLRRALKTGEFRP
                     LPVRERKIPKPGGSGKVRMLGIPTIADRVVQAALKLVLEPIFEAEFKPVSYGFRPLRRA
                     HDAIAEIHFYGTHGYRWVLDADIEACFDSIDHTALMDRVRARVKDKRVLLLVKAFLKAG
                     VLTETGHREDSLTGTPQGGILSPLLANIALSALDEHLTGPWEPGAEMSTASRRSRRRRK
                     GLPNWRIVRYADDFVVLVDGSRDDTEALRGEIADVLGPLGLRLSEGKTQVVHMSDGFDF
                     LGFRIQWCRKRGSDKWYVYTFIADRPIRQLKDKIRALTNRTSQRDPRTVLIRLNQIMRG
                     WANYFKHAVAKVTFKVIQRFVWRRVINWWIVLHRWRKKDVRRRFTDHTGRWKRPSADGV
                     ELFDIQAVAVTRYRYRGNTIPNPWNRLNHA"
ORIGIN
        1 cggcataccc atccttcgcc tcgttcttcg caccccaagt ctgccgtacg aatccggcac
       61 tcccggcact tccccgcacg tccgcgcgcg gcgccgtgcc aggacgggga cccggtagat
      121 catcgtgccc ggcgaccgcc gccgggaacc gcccgcaggg gcgaacgccc gcacgtgcgt
      181 tcagtggcac agacgtgcct cgtgctcggc gtgtccgccc ggctccagct ggaaggtgca
      241 gtgctccacg tcgaagtggt cgccgaggca gccctgcagc tcgtgcagta tcttctcgtg
      301 gccgatggcg ctcagcacgt ccgagctgac caccacgtgc gccgagagca ccggcatgcc
      361 cgaggtgatc gtccaggcgt gcaggtcgtg aacgtcctcc acgccgtcca gtgcgaggat
      421 gtgcgcccgc acctcggaca tgtcgacgtt cttgggggcg gcctccagca gcacgtccag
      481 cgtctcgcgc agcagcttga ccgtcctcgg cacgatcatc accccgatga ccagcgaggc
      541 gaccgggtcg gccccctgcc agccggtggt caggatgacc accgccgaga ccagcacggc
      601 gaacgagccg agcgcgtccg cggccacctc caggaaggcg ccgcgcacgt tcaggctctc
      661 cttctgcccg cgcatcagca gggtcagcga gatcgagttc gcgaccaggc cgatcagacc
      721 gaacacgacc atcagtccgc cgcgcgtctg cgcgggagtg acgaaccgct cgatcgcctc
      781 gtacagcacg tagccgccta cgccgagcag cagcaggcag ttcgccaggg cggcgaggat
      841 ctcggcgcgg gcgagaccga acgtgcggtt ggtgctcggc gggcggttcg cgaagtggat
      901 cgcgagcagg gccatgccga ggcccaccgc gtcggtcgcc atgtgcgccg cgtccgcgat
      961 cagcgcgagc gagtccgcgg ccaggccgcc gacgatctcg acgaccatga tcgtcagtgt
     1021 gatgcccagc gcgatccgca gtcgcccgcg gtacgccgcc gcggccgtac ccgtggccgg
     1081 cgcatggctg tgcgcgtgcc cgtggtcgtg ccctgccccc atggagaaac cacccttcct
     1141 gtgcccttgc gggatccgtc cggcaggccc agtgaactac gggtgggggg tatggggcaa
     1201 cgcggcattg aacaccgttg tcatgtgccc tgacctgcgg aaacgttccg caggtcaggg
     1261 cgctgcgggc tcagcccccg tggtgcagct gccagccctg ccaggccgag gcgaccatct
     1321 cgcgcacatc gcgccgggcc cgccagccca gctcccgcgc cgcccgctcg gccgaggcca
     1381 ccgcgcgcgg cgcgtcgccc ggccggcgcc cctccaccac gggttcccgg cggtctccgg
     1441 tcacctcgcc gatgaccgtg atcagctccc gcaccgagac accctcgccg cgcccgacgt
     1501 tcagcgtcag gtccccggac aggtccccgt cggcgagccg ccgggccgcc gccaggtgcg
     1561 cctcggcgag atcggccacg tggacgtagt cccggacgca ggtgccgtcg ggcgtcggat
     1621 ggtcgtcccc gaagatcctc ggggcctcgt cgcgggtgag ccggtcgaag accatcggca
     1681 cgatgttgaa cacgcccgtg tccgccagct ccggcgccgc cgcgcccgcc acgttgaagt
     1741 agcgcaggca cacggtggag atcccgtgcg cccgccccgc ggcccgcacc agccactccc
     1801 cggccagctt ggtctcgccg taggggttca ccggggcgca gggggtgtcc tcggtgatca
     1861 ggtccacgtc cggattgccg tacacggccg ccgacgagga gaacagcagc cgccggaccc
     1921 ccgcctctgc gaccgcgtcc agcagcgtgg cgaggccacc cacgttctcc cggtaataac
     1981 gggtgggccc ggccaccgac tccgcgacct gcttgcgcgc cgcgagatgg acgacgcccg
     2041 tgacgccgta ctgcgtcagg acccgcttga gccggtcccc gtccagcgtc gagccctcga
     2101 cgagcgggac gtcggcgggc aaccgggcgg gcaccgccgc cgacaggtcg tccagcgcca
     2161 ccacgctctc cccggcgccg gccatggccc gtgccacatg cgccccgatg tatccggctc
     2221 ctccggtgat cagccacgtc atggtcgccc agcctaggcc gacctcccct gccggagcga
     2281 agcgcagctg cgctcgtgcc ggtgggccgg tgggcagcgg gggccgggac gcgggtccgg
     2341 agggggccgg gacgcgggcc cgggaggtgt cccggttgcc cggatctgcg ccgacggttt
     2401 gtcggccggg ccccgaatcc ccgatgatga tcgcggcaaa ggccggggca gcccccgtgg
     2461 gccgggccgt gaacggccgg tgaacacgga ttccggccca tcggatagcc ttcgccgaca
     2521 tgtcgcccgg gtgccgcaga caggcgcccc accatgcaag cgaccggcgc ccgtgcgtcg
     2581 gcacccaggg agtgagttcg gttgtcgacc gccatcgtca ccggtcagcc ggtacccgga
     2641 tcgtccctgg agaacgatct gcggtccctc ggcttcgacg tgcgcgtggc ggaggacgcc
     2701 tccgaggccg agaccctgct cgccgccgcc ccggccggtg aacgtgttgc cctggtcgac
     2761 gccggcttcg tcggccacca gcacgccctg cgcctcggcc tgaccgaccc tcgcttcgag
     2821 ctgtccgccg tccccggcgc cgtcaccgcc cagccggccg cccggcaggc gctgacccgg
     2881 gccgtggccc gcgagacctt cccgggcggc ggtacggccc tcgcggtcga cagcctgacc
     2941 gaccgcatcg tcaccgccct cgacgccgac ggcagcgagg tgcaccggcc cgagctgggc
     3001 agcctagtcg ccgccgtccc cgccgacccg caggcccgca acgaggcccg gcaggccgtc
     3061 gccgccgtgg acgaggaggc cgtacgcctg aagtcggccg tgaagtcccg tgacggattc
     3121 ttcaccacct tcttcatcag cccgtactcg cgctacatcg cccgctggtg cgcccgccga
     3181 ggcctgaccc cgaaccaggt cacgacggcc tcgctgctca ccgccctgat cgcggcgggc
     3241 tgtgcggcga cgggcacgcg cgcggggttc gtcgcggccg gtgtgctgct gatcgcgtcc
     3301 ttcgtgctgg actgcaccga cggccagctc gcccgctatg ccctcaagta ctccacgctc
     3361 ggcgcctggc tcgacgccac cttcgaccgg gccaaggagt acgcctacta cgccggcctc
     3421 gccctcgggg cggcccgcgg cggcggccac gacgatgtat gggccctcgc gctcggcgcg
     3481 atgatcctgc agacctgccg gcacgtggtc gacttctcct tcaacgaggc caaccacgac
     3541 gccaccgcca acaccagccc caccgccgcc ctctccgaca ggctcgacgg cgtcggctgg
     3601 acggtgtggg cgcgccggat gatagtcctg cccatcggcg agcgctgggc gctgatagcg
     3661 gtcctcaccg cggccaccac accccggatc accttctacg tcctgctcgt cggctgtgcc
     3721 gtcgcggcga cgtacaccac ggcgggccgg gtgctgcggt ccctgacccg caaggcgcgg
     3781 cggaccgatc gggccgccgg ggcgctcgcc gacctggccg actccggccc gctcaccgag
     3841 gtcgtacagc gtgtgctcga gcggggcctg ccgggtctcg cggtccccgc ggtcgccctt
     3901 gcgggaggcg ccgcggtcct cgcctgcgcg gccgtcaccg acttcggctc ggcactgccg
     3961 gtgatcggcg ccctggtcta cgtcctcacc tcggccttcg ccgtcgcccg ccccctcaag
     4021 ggcgccctcg actggctggt cccgccgttc ttccgcgccg ccgaatacgg cacggtactg
     4081 atcctcgcgg ccagggcgga cgtgaacggc gcccttccag cggctttcgg gctggtggct
     4141 gccgtcgcct accatcacta cgacacggtg taccgcatcc gcggcaacgc cggagcgcca
     4201 ccggcctggc tggtgcgcgt catcgggggg cacgacgggc ggacgctgct cgtcgccgtc
     4261 ctggctgcgg tcctcaccgc tgcacagttc acggtcgcgc tcacggtcct cgccgtggcc
     4321 gtagccctcg tggtgctcgc cgagagcatc cgcttctggg tgtccgcagg ggcgcccgcc
     4381 gtacacgacg aaggagaatc cgcatgatcg gcctcgtgct ggcggccggc gccggaaggc
     4441 gcctgcgccc ctacaccgac accctgccca aggcgttggt gccggtgggg cccgcgggca
     4501 tagagggcga gcccacggtc ctggacctga ccctcggcaa cttcgccgag atcggcctga
     4561 ccgaggtcgc ggtcatcgtc ggctaccgca aggaggccgt ctacgcgcgc aaggcggccc
     4621 tggaggcgaa gtacggcctc aagctcaccc tcatcgacaa cgacaaagcc gaggagtgga
     4681 acaacgccta ctccctgtgg tgcggccgtg acgccctcaa ggacggcgtg atcctcgcca
     4741 acggcgacac cgtgcacccg gtctccgtcg agaagaccct gctcgccgcg cgtggcgagg
     4801 gcaagaggat catcctcgcc ctcgacaccg tgaagtccct cgcggacgag gagatgaagg
     4861 tcgtcgtcga ccccgagaag ggcatgacga agatcaccaa gctgatggac cccgccgagg
     4921 ccaccggtga gtacatcggc gtcaccctca tcgagggcga cgccgccccc gacctggccg
     4981 acgcgctcaa ggcggtctgg gagaccgacc cgcagcagtt ctacgagcac ggctaccagg
     5041 agctggtcaa ccgcggcttc cggatcgacg tggcgccgat cggcgacgtc cagtgggtcg
     5101 agatcgacaa ccacgacgac ctcgccaagg gacgggagat cgcgtgccgc tactgacccg
     5161 gctcattccc tcgccggtcg tcgtggacat ccgcccgggt gccctggacg acctggccgg
     5221 cgttctcgcc gacgagcgca tcgcgcagtc cggccggctc gccgtcgcgg tcagcggtgg
     5281 ttccggggcc aagctgcgcg agcgcatcgc cccctcactg cccggcgcct cctggtacga
     5341 agtgggcggc ggcaccctcg acgacgcgat ccggctggcc ggcgagatga agtccggtca
     5401 ctacgacgcg gtcgtcgggc tcggtggcgg caagatcatc gactgcgcca agttcgccgc
     5461 ggcccgcgtc ggcctgcccc tggtcgccgt accgacgaac ctcgcgcacg acggcctgtg
     5521 ctcgccggtc gccaccctcg acaacgacgc cgggcgcgga tcctacggtg tgccgaaccc
     5581 gatcgcggtc gtcatcgacc tggacgtgat ccgcgaggcc ccggcccgct tcgtccgggc
     5641 cggcatcggc gacgcgatct ccaacatcaa cgcggtcgcg gactgggagc tgtccaaccg
     5701 ggtcaccggc gagaaggtcg acggtctcgc cgcggccgtg gcccgccagg ccggcgaggc
     5761 ggtgctgcgg caccccggcg gcatcggcga caacgacttc ctccaggtgc tcgccgaggc
     5821 gctggtgctc agcggcatct cgatgtccat ctccggtgac tcccggccgt cctcgggctc
     5881 ctgccacgag atcaaccacg ccttcgacct gctgttcccc aagcgggcgg ccgcccacgg
     5941 cgaacagtgc gggctcggcg cggccttcgc gacgtatctg cgcggggccc acgaggaggc
     6001 ggcccacacc gccgaggtcc tgcgccggca cgggcttccg gtgctgccgg aggagatcgg
     6061 cttcaccgtg gacgagttcg tccgcgcggt ggagttcgcc ccggagaccc gccccggccg
     6121 ctacacgatc atcgagcacc tcgacctcaa gccgaaccag atcaaggaca tctacgccga
     6181 ctatgtcaag gccatcggta gctgaactcc gtccggtcgt tcaccccgcg ggggtgaagg
     6241 accggcgcag cggtgagcac tggatgggac gcctctacat gcgtgaggtg tccctgcggg
     6301 tcgaccgcta cctggtcaac accagggtca cgcccaacca gctcacgtac ctgatgaccg
     6361 tcttcggcgt gctcgccgcc ccggcactcc tggtgccggg gatctggggc gccgtgctcg
     6421 gcgtggtctg cgtccagctg tacctgctgc tggactgcgt cgacggcgag atcgcccgct
     6481 ggaagaagca gtactcgctg aacggcgtct acctcgaccg ggtcggcgcc tatctgaccg
     6541 acgccgccgt gctcgtcggc ttcggcctgc gcgccgccga cctgtggggc ggcggccgtg
     6601 tcgactggct ctgggccttc ctcggcacgc tggcggcgct cggtgccatc ctgatcaagg
     6661 ccgagaccga cctcgtcggc gtcgcccgcc accaggcggg caagccgccg gtccaggaag
     6721 ccgccgccga gatgcgctcc tccggcatga agctggcccg ccgcgccgcc gccgccctca
     6781 agttccaccg gctgatcctc ggcatcgagg cgtccttgct gatcctggtg ctggcggtcg
     6841 tcgaccacgt gcgcggcgac ctgttcttct cccggctggg tgtcgcggtg ctggccggta
     6901 tcgccctgct gcagaccctg ctgcacctgg tgtccatcct cgcttccagc aggctgaagt
     6961 gagtgccgtg aaggtcggcg ccgtcatcat caccatgggc aaccggcccg acgagctgaa
     7021 ggccctcatc gattcggtcg ccaagcagga cggcgaccgt atcgaggtgg tcgtcgtcgg
     7081 caacggctcg cccgtcccgg acgtccccga gggcgtacgg acgatcgagc tggccgagaa
     7141 cctgggcatc cccggcggcc gcaacgtcgg tatagaggcc ttcgggcccg gcggccggga
     7201 tgtcgacata ctgctgttcc tcgacgacga cgggctgctc gcccggcacg acaccgctca
     7261 gctgtgccgc gaggcgttcg aggccgaccc cgaactgggc atcatcagct tccgcatcgc
     7321 cgaccccgac accggcgaga cccagcgccg ccatgtgccc cggctgcgcg cctccgaccc
     7381 gatgcgctcc tcccgggtca ccaccttcct gggcggcgcc aacgccgtgc gcacccgggt
     7441 cttcgccgag gccgggacct tgccggacga gttcttctac gcgcatgagg agaccgacct
     7501 ggcctggcgg gccctggacg ccggctggat gatcgactac cggtcggaca tggtcctgta
     7561 ccaccccacg accgcgccct cgcggcacgc ggtctaccac cgcatggtcg cccgcaaccg
     7621 ggtctggctg gcgcgccgca acctgcccgt cctcctggtc cccgtctacc tcggtgtctg
     7681 gctgctgctc acactgctgc gccgtccgtc cgccccggcc ctgaaggcct ggttcggcgg
     7741 cttcaaggag ggctggacga cgtcgtgcgg cccgcgccgc cccatgcgct ggcgcacggt
     7801 gtggcggctg acccggttgg gccggcctcc ggtgatctga gaagcttctc ttacccgaag
     7861 agagcaagct tcttaccaag agagtccgga tttccactcg tgagtcacac aacccatgac
     7921 ggcggtgccg ccgcggtgaa cgcgataccg tcgcccgacg agggactgac ggccgcgcag
     7981 ctcgccgcca agtacgggct tgccgtcagc ggcgcccgcc cctcgctcgc cgagtacgtc
     8041 cgtcagctgt ggggcaggcg ccacttcatc ctcgccttct cacaggcgaa gctgaccgcg
     8101 cagtacagcc aggccaagct cggccagctc tggcaggtgg cgacaccgct gctgaacgcc
     8161 ggcgtgtact acttcatctt cggcgtcatc ctgcacgcga gccgcggcct gtcccaggac
     8221 gtgtacatcc cgttcctggt caccggcgtg ttcgtgttca ccttcaccca gagttcgatc
     8281 atgtcgggcg tccgggcgat ctccggcaac ctgggcctgg tgcgcgccct gcacttcccg
     8341 cgcgcctcgc tgcccatctc cttctcgctc cagcagctcc agcagctgct cttctcgatg
     8401 atcgtgatgt tcgtcgtggc ggtcgggttc ggcagctacc cgagcccgtc ctggctcctg
     8461 atcgtgccgg tcctgctgct gcagttcctg ttcaacaccg ggctggcgct gatcgtggcc
     8521 cgcatgggcg ccaagacgcc ggacctcgcc cagctgatgc cgttcatcct gcgcacctgg
     8581 atgtacacct ccggcgtgat gttctccatc agcaagatca tggagggccg ctcggagctg
     8641 gcggtccggc tgctccaggt caatccggcc gcggtctaca tggacctgat gcgctacgcg
     8701 ctgatcgacg gctacggcgc cgccaacctg ccgccgcacg tgtgggccat cgcgctgttc
     8761 tgggccgtcg ccgccttcgc cggaggtttt gtgtacttct ggaaggcgga ggagaggtac
     8821 ggccgtggct gagcagaacg ccgggcagaa gatccccggg cagaacaccg gcgagcgccg
     8881 ccccaccgtc atcgccgacg acgtgcacat cgtctaccgc gtcaacggcg ccaggaccgg
     8941 caagggcagt gccacggccg cgctgagcag gatcctcaag cggggctccg acgacgcggc
     9001 gcggggcgtg cgcaaggtgc acgccgtgcg cggggtgtcc ttcgtcgcct accgcggcga
     9061 ggccgtcggt ctgatcggct ccaacggctc cggcaagtcg accctgctgc gcgccatcgc
     9121 cggtctgctg cccgcggagc gcggcaaggt ctacaccgaa ggccagccct cgctgctggg
     9181 cgtcaacgcg gccctgatga acgacctcac cggtgagcgc aacgtcatcc tgggcggtct
     9241 cgccatgggc atgtcccggg agcaggtcaa ggagcgctac caggagatcg tggacttctc
     9301 ggggatcaac gagaagggcg acttcatcac tctgccgatg cggacgtact cctccggtat
     9361 ggccgcccgg ctgcgtttct ccatcgccgc cgccaaggac catgacgtcc tcatgatcga
     9421 cgaggccctg gccaccggtg accgcaagtt ccagatgcgc tccgaggagc gcatccgtga
     9481 actgcgcaag gaggccggaa cggtctttct ggtgagccac aacaacaagt ccatccgcga
     9541 cacctgcgac cgcgtcctgt ggctggagcg cggcgagctg cgtatggacg gcccgaccga
     9601 agaggtgctc aaggagtacg agaagttcac ggggaagtag cctgttttcg gccaggggtc
     9661 cgtcggagtc cgtccggccg ggccccgggc tgcaaaggaa acgtcaactc gggctcgcgc
     9721 aaggaatctt ggcgtcaatc ggtgcgttgt tgtgatctgc aggactcccc ggcggacctc
     9781 gatgcgttgt acaacgtaag ctgtaccagt gccggaaagc ggcaagtggg gcgataatgc
     9841 gcgacaccct gcgccagggc gaccccgtga attgccgggc ggcgtgtccg aaatagtgtg
     9901 tattgggtcg gcagtgtaga acgggagatg tgacggcaat ggctacggaa actcccctgc
     9961 tcaacgcagc atgtgccgtc cccgcccagg gcagcgcccg atgacggcca ccgaggcggc
    10021 gccggccctg cagcgtgcca ccctggacaa ggccgcgagc gagaacttcc ccgtggcccc
    10081 cttcttcctg ccccgggcgt ggcgcgacga cctcatggcc gtctacggct tcgcccgtct
    10141 ggtggacgac atcggcgacg gggacctggc gcccggcggc gccgacgccc gtgccctcgg
    10201 cgtgtcgccc gacggggccg aggaccgcct ggtcctgctc gacgccttcg agaccgacct
    10261 gcgccgcgtc ttcgacggca gcccgcacca cccgctgctg cgccgcctgc agcccaccgt
    10321 ccgctgccgc ggcctcaccc ccgagccctt cctcggcctg atcgccgcca accgccagga
    10381 ccagctcgtc agccggtacg agacctacga cgacctcctg gcctactgcg aactgtcggc
    10441 caaccccgtc ggccgcctcg tcctcggggt cacgggcacc gcgacccccg agcggatccg
    10501 cctctccgac gcgatctgca ccgcgctgca gatcgtcgaa cacctccagg acgtggccga
    10561 ggacctcgcc cgcgaccgga tctacctccc ggccgtcgac atgaagcgct tccacgtgca
    10621 ggaagcggat cttggcggga aatccgcagg cgcatcggtg cgcgccctgg ttgcatacga
    10681 agcacaacgc gcccgcgatc tgttgaatga aggcgccccc ctggtgggta gcgtccacgg
    10741 caggttgaag ctgctgctcg cagggttcgt ggcgggggga agagcggcga tcagggcgat
    10801 cgccgccgcc gaatacgacg tacttcccgg cccgcccaga cccggcaagg tccagttgct
    10861 gcgtgaggcg ggcgtgatcc tgcgagaaga ggggtgatcc ggaccgtgga gtctccgtcg
    10921 cacgtgtccg cgccggtgct cgccgcctac agctactgcg aggccgtcac cgggcagcag
    10981 gcccgtaact tcgcgtacgg catccggctg ctgcccacgc ccaagcgtcg cgccatgtcg
    11041 gcgctgtacg cgttttcccg gcgcgtggac gacatcggcg acggcgacct gcccggcgag
    11101 accaagctga cccgcctcga ggacaccagg gcgctgctcg cccgggtcca tgagggccag
    11161 gtcgaggagg acgacaccga cccggtggcc gtcgccctcg cccatgccgc cactgccttc
    11221 ccgatcccgc tcggcgggct ggacgagctg atcgacggcg tccagatgga cctgcgtggg
    11281 gagacctacg agacctggga cgacctgaag gtctactgcc ggtgcgtcgc cggtgccatc
    11341 ggccgcctct cgctcggcgt gttcggcacc gaacggggcg cgcgcggtgc cgagcgcgcc
    11401 gccgagtacg ccgacacgct cggtctcgcg ctgcagctca ccaacatcct cagagacgtc
    11461 cgcgaggacg ctcagggcgg ccgtacctat ctgcccgccg acgatctggc caagttcggc
    11521 tgctcggccg ggttcgacgg gccgacgcca ccggagggct ccgacttcgc gggcctcgtg
    11581 cacttcgaag tgcggcgggc ccgcgccctt ttcgccgagg gctaccggct gctccccatg
    11641 ctcgaccggc gcagcggcgc ctgtgtggcc gccatggccg gcatctaccg ccggctgctg
    11701 gaccgcatcg agcgcgatcc ggaagctgtg ctgcgcggcc gggtctcgct gcccggacgc
    11761 gagaaggcct acgtggccgt acgcggactg tcgggactcg acgcccgcaa cgtcacccgc
    11821 cacaccgcgc cgcggtccgt caggaggcgc gcctgatgga cctcaccgaa ccaggggaca
    11881 tgcggcaggc aaccctccac ggcggcgtgg cgtcccagac tgcgacggcc gaccgcgcac
    11941 cgttcgacca gcacgctcgc gccccgaagg cacgcggggc cgtgccggcg atgcggttgc
    12001 cgctgcgtgg gtgtgacgag ccacgaggga cccgcggacg gccgacggcc cagcacggca
    12061 ctccccgcgg agcgctcgca cggaaggacg cacgatgacc gaccgctcgc gccccgcaca
    12121 ggcgcacgct gacaccgcgg gagccgaggg ggcggcaggc cgcagtgccg tagtggtcgg
    12181 cggcgggctc gccgggatca ccgccgcgct cgcgctcgcg gacgcgggcg tccgtgtcac
    12241 cctgctcgaa ggcaggccga ggctgggcgg cctcgccttc tccttccagc gcggcgagct
    12301 gaccgtcgac aacggccagc atgtgtacct gcgctgctgc accgcctacc gctggttcct
    12361 cgaccggatc cagggcgcgg cgctggcgcc gctgcaggac cgcctcgacg tgcccgtcgt
    12421 cgacgtcgcc aagcccgaag ggcgacggct cggcaggatc cggcgcgacc cactgcccgt
    12481 cccgctccac ctggggcgca gcctggccgc ctatccgcat ctctcgctcg ccgagcgtgc
    12541 cgcggtcggg cgtgccgcgc tcgcgctcaa ggggctcgac ctcgccgatc cgaccctgga
    12601 cacccaggac ttcggcagct ggctggccgc gcacggccag tcggcgcgtg ccatcgaggc
    12661 cctgtgggac ctggtcgggg tcgccaccct caacgcggtc gcgggcgacg cctcgctggg
    12721 gctcgccgcg atggtgttca agaccggtct gctgtcctac ccgggcgcgg ccgacatcgg
    12781 ctgggcccgc gtccccctgg gcgaactgca cgaccgcctg gcccgcaagg cgctcgactc
    12841 cgcgggcgtc cgtaccgagg tccgtacacg cgtcacctcc gtctctacaa acgagaacgg
    12901 gacgtggagc gttcaggttc ccggcgagac gctgcaaacc gacgcggtcg tcctcgccgt
    12961 accccagcag gagacgcacg acctgctgcc caccggcgcg ctcgatgccc ccgagcggct
    13021 gctcggcatt cctgccgcgc cgatcctcaa cgtgcacatc gtgtacgacc gcaaggtgct
    13081 cgcccgcccc ttcttcgcgg ccctcggtac ccccgtgcag tgggtcttcg accgcacgga
    13141 ctcctccggg ctcgccgcgg ggcagtacct ggcgctgtcg cagtcggccg cgcacgacga
    13201 catcgacgcg cccgtggcca ccctgcgcga gcgctatctg ccggagctgg agcggctgat
    13261 cccgggcacc cggggcgccg tggtgaagga cttcttcgtg acccgggagc gtacggccac
    13321 gttcgccccg gtccccggcg tcgggcggct gcggcccggc gcccgcacca aggcccccgg
    13381 cctgtacctg gccggagcgt ggaccgccac agggtggccc gcgaccatgg agagtgcggt
    13441 ccgtagtgga gtgagcgcgg ccgacgccgc gctgagcgcc ctgggccggc cccgcccccg
    13501 ccgtctcttc gcgttcgagg aggcggcctg atgctcgagc agcaccgggc gggcccccgc
    13561 acccccggca ccgcaacaag aggagagact gtgcccactg tgcccccggc cccgaccccc
    13621 gctcggagga ccgcggtgga cgtgaccgcg ctgctggagc gcggccgaac cctggccaca
    13681 ccggtcctgc gttcggctgt cgaccggctg gcgcctccca tggacaccgt cgccgcctac
    13741 cacttcggct ggatcgacgc ggccggaaac cccgccgccg gcgacggcgg caaggccgta
    13801 cggcccgccc tcgccgtgct ctccgccgag gtcaccggtg ccgcccccga ggtcggcgtg
    13861 ccgggggccg tcgccgtcga actcgttcac aacttctcgc tgctgcacga cgacctgatg
    13921 gacggcgacg agcagcgccg gcaccgtgac accgtctgga aggtgcacgg cccggcccag
    13981 gccatcctgg tcggtgacgc cctcttcgcc ctcgccaacg aggtcctgct ggagctgggc
    14041 accgtcgagg ccggccgtgc cacacgtcgg ctgaccgccg ccagccgcgc cctgatcgac
    14101 ggtcaggcgc aggacatctc ctacgagcac cgcgaccgcg tcagcgtcga ggagtgcctg
    14161 gagatggagg gcaacaagac cggcgcgctg ctcgccgcct ccagctccat cggtgcggtc
    14221 ctcggcggag cggacgacgc caccgccgac gcgctggaga agtacggcta ccacctcggc
    14281 ctcgccttcc aggccgtcga cgacctcctc ggcatctggg gcgacccgga ggccaccggc
    14341 aagcagacct ggagcgacct gcgccagcgc aagaagtccc tgccggtcgt cgccgcgctc
    14401 gcggcaggcg gctccgcctc cgagaagctt ggcgagatcc tcgccgcgga cgccaagagc
    14461 agcgacttcg agaacttctc cgaggaggag ttcgccgccc gcgcggccct gatcgaggag
    14521 gccggcggcc gcgagtggac ggccgacgaa gcgcgccgtc agcacaccat cgccatcgaa
    14581 gccctcgacg tcgtccacat gcccggccgg gtccgggacg ccttcacggc gctcgccgac
    14641 ttcgtcgtcg tacgaaagag atgatcacta tcggctcaag cctcgcgtag tcgccggccg
    14701 gtgtcatacg tacgacgcag gacaccggcc gacggcggac ccacagcagc acgactcgca
    14761 cgactgcact aaggggaagc catgacagcg acgaccgacg gaagcaccgg ggcgaccctg
    14821 ccgtcccacg cggccgcggc cagcgacacc actctcagca cccccgaggc ggccggggta
    14881 caccaagccg ccacacgcgc cgcccggcgc gccaccgact tcctgctggc acggcaggac
    14941 gcccagggct ggtggaaggg cgacctcgag accaacgtca ccatggacgc cgaggacctg
    15001 ctgctccgtc agttcctggg gatccgtgac gagaagacca cgcaggccgc cgcgatgttc
    15061 atccgcagcg agcagcgcga ggacggcacc tgggcctcct tctacaaggg cccgggggaa
    15121 ctgtccacca ccatcgaggc gtacgtcgcc ctgcgcctgg ccggcgacgc gcccgacgag
    15181 gcgcacatgg cgaaagcatc cgcctggatc cgtgagcgtg gcgggatcgc cgcctcccgt
    15241 gtcttcaccc ggatctggct cgccctgttc ggctggtgga agtgggagga cctgcccgaa
    15301 ctcccgccgg aactgatcta cttcccgacc tggatgccgc tcaacatcta cgacttcggc
    15361 tgctgggccc ggcagacgat cgtgccgctg accgtcgtct cggccaagcg tccggtgcgc
    15421 ccggcgccct tcccgctgga cgagctgcac accgacccgg ccagccccaa cccgcccagg
    15481 ccgcttgctc cggtgacgag ttgggagggc gccttccagc ggctggacaa ggggctgcac
    15541 cagctgcgca aggtcgtccc gcgcaggctg cgcagggcgg cgatggactc ggccgcccgc
    15601 tggatcatcg agcggcagga gaacgacggc tgctggggcg gcatccagcc gccggccgtg
    15661 tactcggtca tcgccctgca cctgctcggc tacgacctcg agcaccccgt gatgcgcgag
    15721 ggcatcgcct cgctggaccg tttcgccgtg tggcgcgagg acggctcccg gatgatcgag
    15781 gcctgccagt ccccggtgtg ggacacctgc ctcgccgcca tcgcgcttgt cgacgcgggg
    15841 ctgcccgccg atcatccgca actggtcaag gcggccgact ggatgctcgg cgaggagatc
    15901 gtccggcccg gggactgggc cgtgaagcgc cccggactgc cgccgggcgg ctgggcgttc
    15961 gagttccaca acgacaacta cccggacatc gacgacaccg ccgaggtcgc gctcgcgctg
    16021 cgccgggtcg gccaccacga ccccgagcgc atggacaagg ccattgcgcg ggcggtgcgc
    16081 tggaacctgg ggatgcagtc gaagaacggc gcctggggcg ccttcgacgt cgacaacacc
    16141 agcccgttcc ccaaccggct gccgttctgc gacttcggcg aggtcatcga cccgccgtcg
    16201 gcggacgtca ccgcgcacgt cgtggagatg ctcgccgccg agggtctcgc ccacgatccg
    16261 cgcacccggc gcggcatcga ctggctgctc gccgaacagg agtcgaacgg ctcgtggttc
    16321 ggccgctggg gcgtcaacta catctacggc accgggtcgg tggtccccgc cctgaccgca
    16381 gccgggctgc ccggctcgca cccggcgatc cggcgggccg tggcctggct ggagagcatc
    16441 cagaacgacg acggcggctg gggcgaggac ctgcgctcct acaagtacgt caaggagtgg
    16501 agcggtcgtg gcgcctccac cgcctcgcag accgcgtggg cgctcatggc gctgctcgcg
    16561 gcgggggagc aggactccaa ggccgtcgag cgcggtgtgc agtggctggc cgacacccag
    16621 cgggaggacg gcagctggga cgagccgtac ttcacgggca ccggcttccc ctgggacttc
    16681 tccatcaact accacctgta ccggcaggtc ttcccgctca ccgcgctcgg ccggtacctg
    16741 cacggcgacc cgttcgagcg tggcctgctc gccagaaaac cccactccga ggtcaaggtg
    16801 ggctgaggtg agcactcagc ccgcaccggc cccgctgctg atcgcctgcg cgctcggcat
    16861 cgagcacctc gccctgcgca ccggcgaccg tcacggggcc gacgggccgg tcaccttcct
    16921 ccgtacgggc atggggcccc gtgcggcgga acgctccgtc acccggcggc tcgccgtccc
    16981 ggcgctcgcc gaggccgccg tgctggccac cggcttctgc gcggggctcg cccccggtat
    17041 gcaccccggt gacctggtgg tcgccgagga gaccagggac ccgcgcggca gcgtcccgtg
    17101 cgtgggtacc gagttgctgg tcaaggaact cgtacgcctg ctgcccgggc gcacggtcca
    17161 caccggaccg ctcaccggct ccgaccacgt cgtgcgaggt ccggagcgcg cgcagctgct
    17221 cgcgcgaggc gcgatcgcgg tcgacatgga gtcggccgcc acgctcctcg ccgctgcgcg
    17281 caccggtgag cgtccggttg cggccgtgcg ggtggtcgtg gacgcaccag aacatgaact
    17341 cgtccggatc ggaacggtac gcggtggaat atcagctttc cgtgttcttc gttccgtgct
    17401 tcccgcattt ttcgaatggc accgttcttc gctgctcccc aggaggtgag ccagatggcc
    17461 atgccgctgc gtcagaccat caaggtcgct acgtacttgt tcgaacagaa gctcaggaag
    17521 cgggacaaat tcgccctgct ggtcgaattg gagccgctgt tcgcctgcaa cctcaagtgc
    17581 gagggctgcg gcaagatcca gcacccggcg ggtgtgctca agcagcggat gcccgtggcg
    17641 caggccgtcg gagccgttct cgagtccggt gcgccgatgg tgtccatcgc gggcggagag
    17701 ccgctgatgc accctcagat cgacgagatc gtacggcagt tggtggccaa gaagaaattc
    17761 gtcttcctgt gcaccaacgc gctgctgatg cgcaagaaga tggacaagtt caaaccctcc
    17821 ccgtacttcg cgtgggccgt gcacgtcgac gggctgcgcg agcggcacga cgcctccgtg
    17881 gcgaaggagg gcaccttcga cgaggcggtg gaggccatca aggaggccaa gcggcgcggc
    17941 ttccgggtga ccaccaactc gaccttcttc aacacggaca ccccgcagac cgtcatcgac
    18001 gtgctgaact tcctcaacga cgacctcaag gtggacgaga tgatgctctc gcccgcctac
    18061 gcctacgaca aggctcccga ccaggagcac ttcctcggcg tacagcagac ccgggagctg
    18121 ttcaagaagg ccttctcggg gggcaaccgc gccaagtggc ggctcaacca gagcccgctc
    18181 ttcctggact tcctggaagg caaggtcgac ttcccttgca ccgcgtgggc gatcccgagc
    18241 tactccctct tcggctggca gaagccctgc tacctgatga gcgacggtta tgtgcccacc
    18301 taccggcagc tgctggagga gaccgactgg gaccagtacg gccgcggcaa ggacccgcgc
    18361 tgcgacaact gcatggcgca ctgcggctac gagcccaccg ccgttcttgc caccatgggc
    18421 tccctgaagg agtcgctgcg ggcgatgcgc gagaccgtct cggggaaccg ggagtgacgg
    18481 cgtgagcgcc gttcccctgg gcgttcccga ggtgccggcc cggccggtcg caccgcggcg
    18541 gcagtcgcgg cagatcagcg tcgggccggt ggcggtcggg ggcggggccc cggtgtcggt
    18601 gcagtcgatg acgacgaccc gtacgtcgga catcggcccc accctccagc agatcgcgga
    18661 actcaccgcg tccggctgcc agatcgtccg cgtcgcctgc cccacgcagg acgacgcgga
    18721 cgccctcgcc acgatcgcgc agaagtcgca gatcccggtg atcgcggaca tccacttcca
    18781 gcccaagtac gtgttcgcgg ccatcgaggc cggctgtgcc gccgtgcgcg tcaatccggg
    18841 caacatcaag aagttcgacg accaggtgaa gcagatcgcg cgggccgcgg gggagcacgg
    18901 cacgccgatc cggatcgggg tcaacgccgg ttcgctggac cggcggttgc tccagaagta
    18961 cggcagggcc actcccgagg cgctggtgga gtcggccctg tgggaggcgt cgctcttcga
    19021 ggagcacgac ttccgtgaca tcaagatctc ggtcaagcac aacgacccgg tcgtgatgat
    19081 cgaggcctac cggcagctgg ccgaacagtg cgactacccg ctgcacctgg gtgtcacgga
    19141 ggccggtccg gccttccagg gcacgatcaa gtcggcggtc gccttcgggg cgctgttgtc
    19201 gcggggcatc ggcgacacca tccgggtgtc gctgagcgcg ccgccggccg aggaagtcaa
    19261 ggtgggcatc cagatcctcc agtcgctggg cctcagacag cggcgtctgg agatcgtctc
    19321 ctgtccgtcc tgcggccggg cccaggtgga tgtgtacaag ctcgccgagg aggtcacggc
    19381 gggactggac ggcatggagg tgccgttgcg tgttgcggtg atggggtgtg tggtcaacgg
    19441 tccgggtgag gcccgcgagg ccgacctcgg ggttgcctca ggcaatggaa aggggcagat
    19501 cttcgtgaag ggcgaggtcg tcaagaccgt gcccgagtcg aagatcgtcg agaccctcat
    19561 cgaggaggcc gcgaagattg ccgagcggac gagccccgca gacaagtgag ttgaggcaag
    19621 cacggaccga gagggggccc agcgtgacca ttctggagaa catccgggga ccacgcgacc
    19681 tgaaggcgct gtccgaggcg gaactcggtg aactgtccca cgagatacga gagttcctcg
    19741 tccaggccgt gtcgaggacc ggcggtcatc tcggacccaa tctgggcgtg gtggagctgt
    19801 ccatcgcgct gcaccgggtc ttcgagtcac cggccgaccg catcctgtgg gacaccggac
    19861 accagagcta tgtgcacaag ctgctgacag gccgtcagga tttctccaaa ctgcgcggca
    19921 agggcggact gtccggatac ccctcgcgcg aggagtccga gcacgacgtc atcgagaaca
    19981 gccacgcctc cacagcgctc ggctgggccg acggcctggc caaggcgaac caggtgctgg
    20041 gggagaagag ccatgtggtc gcggtcatcg gcgacggcgc actgaccggc ggcatggcct
    20101 gggaggcgct caacaacatc gcggccgcca aggaccggcc gctgatcatc gtcgtcaacg
    20161 acaacgagcg ctcgtacgcc ccgaccatcg gcggcctcgc caaccacctg gccgccctgc
    20221 gcaccaccga cggctacgag aaggtcctcg cctggggcaa ggacgtactg ctgcgcaccc
    20281 cggtcgtcgg caacacgatc tacgagtccc tgcacggcgc gaagaagggc ttcaaggacg
    20341 ccttcgcccc gcagggcatg ttcgaggacc tcggcctgaa gtacgtcggc ccgatcgacg
    20401 gccatgacct caaggccgtc gagtcggcgc tgcgccgcgc gaaacgtttc cacggtcccg
    20461 tcctggtgca ctgcctgacg gagaagggcc gtggctacga gccggccctc gcccacgagg
    20521 aggaccactt ccacagcgtc ggcgtgatgg acccgctcac ctgcgagccc ctcgcgccct
    20581 cgggcggtcc gtcctggacg tcggtgttcg ctgacgagat cgtccggatc ggcgaggagc
    20641 gtgacgacgt cgtcgccatc accgcggcca tgctgcaccc ggtgggcctg gccaagttcg
    20701 ccgagcgctt cccggagcgg gtgtgggacg tgggcatcgc cgagcagcac gcggccgtct
    20761 ccgcggccgg ccttgcgacc ggcggactgc acccggtcgt cgccgtctac gcgaccttcc
    20821 tcaaccgcgc cttcgaccag ctgctgatgg acgtcgccct gcaccgctgc ggggtcacct
    20881 tcgtcctgga ccgggccggt gtcaccggcg ccgacggcgc ctcgcacaac ggtatgtggg
    20941 acatgtccgt cctgcaggtc gtccccggcc tcaggatcgc cgccccgcgc gacgccggcc
    21001 agctgggcgc ccagctgcgc gaggccgtcg ccgtggacga cgcgcccact ctgatccgct
    21061 tccccaagga gtcggtcggc cccgacatcc cggccgtcgc ccaggtcggc ggcatggacg
    21121 tcctgcaccg cggcgagcgc cccgaggtgc tgctggtggc cgtcggtgtg atggcgccgg
    21181 tgtgcctcca ggccgccgac ctgctccagg cgcgcggcat cgactgcacg gtggtggacc
    21241 cccgttgggt caagccggtc gatccggcgc tgcccggact cgcggccgag caccggctgg
    21301 tggccgtggt cgaggacaac agccgtgcgg cgggcgtcgg ttcggccgtc gccctggccc
    21361 tcggcgacgc cgacgtggat gtgccggtac ggcggttcgg catcccggag cagttcctcg
    21421 cgcacgccaa gcgcggcgag gtgctggccg acatcggact cacgcccgtc gagatcgccg
    21481 ggcggatcgg cgcgagtctc gcggtgcggg acgccgcggg cgcggccgca ggctccgggc
    21541 agggccgcac cgcggccgtg gcaccgtcgg ggacggtcgc acccccgaac tctcggctcc
    21601 gttcaagcgg ggaggtgccc ccggcgcggc ggcagccgca cgccgacagg gcccccgcgc
    21661 tccttcggag cgctgacaag gagaaggaat gagcacggag ttcgacctcg gcgccaccct
    21721 cgccgagcgc ggagccgaac gctacgagct gcacacgaag tacctcaacc cacagctccc
    21781 gcggatgctg cacaccatcg gcttcgacaa ggtctacgag cgggccgagg gcgcccactt
    21841 ctgggacgcg gaaggcaacg actacctgga catgctcgcc ggcttcggcg tgatgggcct
    21901 cggccggcac cacccggtcg tccgcagggc gctgcacgac gtcctcgacc tcgacctcgc
    21961 cgacctcacc cgcttcgact gccagccgct gcccggcctg ctcgccgagc ggctgctcgt
    22021 gcacagtccg cacctggacc gggtgttctt cggcaacagt ggcaccgagg ccgtcgagac
    22081 ggccctgaag ttcgcccgct acgccaccgg aaagccccgc gtcctctact gcgaccacgc
    22141 cttccacggc ctgaccacgg gctccctctc cgtcaacggg gaggacggtt tccgcgacgg
    22201 gttcgccccg ctgctgcccg acaccgccgt accgctcggt gatctcgacg ccctggcacg
    22261 ggagttgagc aagggcgacg tggccgccct gatcgtggag ccgatccagg gcaagggcgt
    22321 gcacgaggcc ccgccgggtt acctgcgcgc cgcccaggac ctgctgcacc gccacaaggc
    22381 cctgctcatc gccgacgagg tgcagaccgg cctcggccgc accggcgact tctacgccta
    22441 ccagtacgag gacggtgtcg agccggacct ggtgtgcgtg gccaaggcgc tctccggggg
    22501 ctacgtcccg gtcggggcga ccctcggcaa ggactggatc ttcaagaagg tctactcgtc
    22561 catggaccgc gtgctggtcc actcggcgag cttcggctcc aacgcccagg ccatggcgtg
    22621 cggcctcgcc gtgctgtcgg tcatggagaa cgagcagatc gtcgccgggg tgcggaccac
    22681 cggcgagctg ctcaggtccc ggctggccgc gctgatcgag aagtacgagc tgctcgccga
    22741 cgtgcgcggc cgtggcctga tgatcggcat cgagttcggc aagccgtcct cgctcaagct
    22801 gcgcagccgc tggaccgtgc tccaggcggc ccgcaagggc ctgttcgcgc agatggtcgt
    22861 cgtaccgctg ctgcaacggc accggatcct cacccaggtc tccggcgatc acctggaggt
    22921 gatcaagctg atcccgccgc tggtgctcga cacggcggac gtggaccggt tcgtggacgc
    22981 cttcaccgcc gtgatggacg acgcgcacag cggtggcggt ctgatgtggg acttcggcaa
    23041 gaccctgatc aagcaggcgg tggccaaccg ctgaccgccg tgcccggtac agcaccacga
    23101 agaggaggaa gaggccgacg agcccgaccg cgcccagcac ggtccccgtc accgaggtcc
    23161 acagccggct gcacctccgg ccggcgtagt ggatccccat ggcgccgaag gtgacggcga
    23221 gaccggctgc gagcagcgac caggggaaca ccaggaaggt ctgcgtgggc caggcgcccg
    23281 cggcggcgac ggctccgagg acgagggaga gcgggccgag ggcaccggcg ggcgagccgg
    23341 ccgaacgggg tgtgtccgat ccggacatga tgcggtcccc cagtttttga acgtgttcaa
    23401 gtccttgggg ggcctagcag cagcccggcc gcagggcgcg ggagatcccc atgacgcgtg
    23461 gcgtcaccgg gccgcgccaa gcttttgcct cacaggcaag aaatttgccg cttaggcaaa
    23521 tctggggctg aatggaggca tgaacgcctc agacgccgcg ccaccggcgg agccgggcga
    23581 cgcacttccc gcggtcgcgc cacagctgcg cgcactgcgt cggcgcgccg gcctcaccct
    23641 ggaggccgcg gcccgcgccg ccgggctctc gcccgcccat ctgtccaggc tggagaccgg
    23701 gcagcgccag ccgtcactgc cgatgctgct cgccctcgcg cgtatctacg gtacgacggt
    23761 ctccgacctg ctcggcgaga cggtcgccga ccgggacgcg atcgtgcggg ccggcgacat
    23821 ggagccgacc cgggcgggcg gctggacgta cttccaggcc ggggcgtccg gccggggcat
    23881 gcaggccctg cgcgtgcagg cgccgtacgg cgcccagggc gacatcgtgc gcgtccaccc
    23941 cggcgaggaa tggctctacg tcctcaaagg ccgcctgcgc ctgcgcctcg gcgacaccgc
    24001 gcacctgctc gcgcccggtg acagcgccca cttcgactcg ctcaccccgc accggctcgc
    24061 cgccgaggac cacgacggcg tcgagctgct gttcgtccac accctgctgc agagccccac
    24121 gaccgcactg tgcctggggc cgttgaccgg agagctgcca tgagcaacta cgagacgaaa
    24181 ttcccccgtt ccctgtggat ccgcctgatc atctacatcg ccgtcggcca cctcctggcc
    24241 gccttcctct acctgctgtt cgcgctgggc ggcaagggct gaccgggccg ggcgtgtgcg
    24301 ctcagtccag caggcgctcg cgcaggcggt cccggtcgat gggggtgagg ccgagagcct
    24361 gctgcaggta ggggtcgaca ccgccccagg tgtcctcgat gctctcgaag gccgcctcga
    24421 ggtactcggc gcgggcgtcg aagagcgggc tgagcagctc catcacctcg ggcgtgtacg
    24481 cactgtccgc gctgccgctg cggcggacct tgtagcggcg gtgcttggcg ttggactcca
    24541 ggtagtcggc gacgatcgcc tcgcgctcca cgccgagggc gaggagcgtc acggctatgg
    24601 agatgcccgc gcggtccttg ccggccgcgc agtgcatcag cgcgggcacg ctgtcctcga
    24661 cgagcgagcg cagcacccgg gagtgctcgg cggtgcgctc cttgacgatc gtccggtacg
    24721 aggcgaccat ccgggccgcc cccttgccgt cggcgaggat cccgcgcagc tggtcgaggt
    24781 cgccgtcccg gaccatcttc cagaactccg cgccgtccgc ggggtcgctc agcggcaggt
    24841 tcatgttccg cacgccgggc agcgcgacgt ccgggccctc cagccgctgg tcggccgcgt
    24901 tacggaagtc gaagatcgtg tgcagaccca gggaggcgag gaaggcggca tcgtcctcgg
    24961 tggcgtgcgc aaggtgcccg ctgcggaaca gcacgccgtg gcgcacccgg cgcccgtccg
    25021 tggtcggcag tccgccgacg tcacggaaat tgcgcacacc ggccagctcc ggctcggtcg
    25081 acgggacctg ctgcgtcacg ggggctcctc ccggtcgggg cccgccgtcg cgtctcggcg
    25141 gcgggcgctc tgtcgaccat acgacatcgg tttcctcggg gttgagtcgg cgcggagcgc
    25201 ggtactggcg tctccaccag cccgtttctc cgcgccgctc gccgaacccg gcgtgcgact
    25261 ctcaccgcac cgggctctcc acggacgctg ccgtttcagg cgtggttgag gcggttccag
    25321 gggttgggga tcgtgttgcc tcggtagcgg taacgggtga ccgccaccgc ttggatgtcg
    25381 aacaactcga ccccgtccgc cgacggtcgt ttccaccgtc cggtgtggtc ggtgaagcgt
    25441 cgacggacgt ccttcttcct ccagcggtgc agcacgatcc accagttgat cacccggcgc
    25501 catacgaagc gctggatgac cttgaaggtg actttcgcga ctgcgtgctt gaagtagttg
    25561 gcccagccgc gcatgatctg gttgagcctg atcagcacgg tcctgggatc ccgctgcgac
    25621 gttctgttcg tgagggcacg gatcttgtcc ttcagctgcc ggatgggccg gtcagcgata
    25681 aaggtgtaga cgtaccactt gtccgatccg cgcttgcggc accactggat gcggaaccca
    25741 aggaagtcga acccgtccga catgtgcacc acctgtgtct tgccctccga gaggcgaaga
    25801 ccgagcggtc ccagcacatc ggcgatttcc ccgcgcagcg cttcggtgtc gtcgcggctg
    25861 ccgtccacga ggacgacgaa atcgtccgcg tagcggacga ttcgccagtt cggcagaccc
    25921 ttgcgacgac gcctggagcg tcgggatgcg gtggacatct ccgcgcccgg ctcccacggc
    25981 ccggtcaggt gctcatcgag cgccgacaag gcgatgttcg ccaggagcgg ggagaggatg
    26041 cccccctgtg gggtgccggt gagggagtcc tcgcggtggc cggtctcggt gaggacgccg
    26101 gccttgagga acgccttgac cagcagcagc acgcgcttgt ccttcactcg cgctcgcacc
    26161 cggtccatca gggccgtgtg gtcgatcgag tcgaagcacg cctcgatgtc cgcgtccagg
    26221 acccagcggt agccgtgggt gccgtagaag tggatctcgg cgatcgcgtc gtgtgcccgc
    26281 cgcaggggtc ggaaaccgta ggagaccggc ttgaactcgg cctcgaagat cggctccaac
    26341 accagcttca gggccgcctg gaccacccgg tcggcgatgg tcgggatgcc gagcatgcgc
    26401 accttcccac taccaccagg cttggggatc ttgcgttcac gcaccggcag tgggcggaat
    26461 tcacccgtct tgagtgcgcg ccgaaggccc tccaggaacc cgtaagggcc aatatcccgc
    26521 tccacgttga cggcggtaag accgtcgacg cctggggtat ttgccccctt atttcccgcg
    26581 acccgttcga acgccacaag cagcgtcgcc gggtcgtaca cgaggttgaa cagatcgtcg
    26641 aacctgcggc cgggatcggc cgccgcccaa cggtgaagtt tggcctgcat ccccgatacc
    26701 cgctggtgag accccatcag agccccggga gcactgctgt tcagcagcgc gtctttcggc
    26761 attgcagcct ccttcccttc tcgaatccgc tgccgccctt ccccat
//
