LOCUS       NZ_CP047020            22222 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Streptomyces broussonetiae strain T44 chromosome.
ACCESSION   NZ_CP047020
VERSION     NZ_CP047020.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces broussonetiae
  ORGANISM  Streptomyces broussonetiae
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9735779)
  AUTHORS   Mo,P.
  TITLE     Streptomyces sp. strain T44 isolated from rhizosphere soil of
            Broussonetia papyrifera
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9735779)
  AUTHORS   Mo,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2019) College of Life Science and Technology,
            Central South University of Forestry and Technology, No. 498,
            Shaoshan South Road, Changsha, Hunan 410004, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 25-OCT-2019
            Assembly Method                   :: HGAP v. 3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 12.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009796285.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 17:56:09
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,022
            CDSs (total)                      :: 8,931
            Genes (coding)                    :: 8,515
            CDSs (with protein)               :: 8,515
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 416
            CDSs (without protein)            :: 416
            Pseudo Genes (ambiguous residues) :: 0 of 416
            Pseudo Genes (frameshifted)       :: 171 of 416
            Pseudo Genes (incomplete)         :: 334 of 416
            Pseudo Genes (internal stop)      :: 29 of 416
            Pseudo Genes (multiple problems)  :: 110 of 416
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:31:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7731146
            Orig. end                         :: 7753368
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP047020.1.
            Bacteria and source DNA available from Zhao YL.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22222
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="27"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..22222
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22222
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12222](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12222
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(463..1317)
                     /locus_tag="GQF42_RS35485"
                     /old_locus_tag="GQF42_35485"
     CDS             complement(463..1317)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019056248.1"
                     /locus_tag="GQF42_RS35485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_35485"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_158926804.1"
                     /transl_table=11
                     /translation="MAMTNNFGIALRGWRERFSPLAGGLESDAHRRIPGLRREELAGLA
                     GLSVDYVVRLEQGRARNPSAQVVTALARALHLGTSERDHLFRCAHLAPPSNGDVSLHVP
                     SSVHRLVRHMGDAPVAVYAADWTLVSWNRMWTAAIGDPLTYGWDQGNLVAGMFRSSDGR
                     RVDSIAAWPVRSWAGDEDEEEALVADLRVTAAAYPDDARLTSLVDRLLHTSPRFAHLWS
                     NGTAGLHTGDRKTIEHPKVGDLTLDLDVLMVPGSDLRIVAYTAVAGTDDAEKLDALRAD
                     SHL"
     gene            complement(1383..2843)
                     /locus_tag="GQF42_RS35490"
                     /old_locus_tag="GQF42_35490"
     CDS             complement(1383..2843)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR00976.1"
                     /locus_tag="GQF42_RS35490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_35490"
                     /product="CocE/NonD family hydrolase"
                     /protein_id="WP_158926806.1"
                     /transl_table=11
                     /translation="MFPFIEYGPIQLYLNNGYAYVVMDVPGTGRSEGTWDPVSRGEGEA
                     IHDMIEHVAAEPWSTGAIGMIGMSHYCWSQWNAARTRPPHLRTIVAYDGATDMYRDWMY
                     HGGIPIQGFLSTWLFGSVLVQHEIEGIGFRVGGKQDFVYDILSHPVDDEWHRRRSPFWE
                     LPQIDIPVFSIGVWGKAALHLRGNFYGFERVRGPKKLLVTHPGSFAAAQRYYFDEDFHR
                     TELLPWYDHHLKGTDNGVMEKPNIRFYVNGEDAYHSAPSWPPPDVRTSTFYLAGEHSGA
                     VDSLNDGTLTETKPVADEASTSWSYPDPEWMAGVTVFDKHGVPDHVARVNTFTTAPMDK
                     DREFTGHATLTLHASTDQTDMDVIVKVSLIPSNSGAKLPIKVSQGWLRASHRAEDPELT
                     SDMRPFHLHNGVDPLEPGKVYELHIELLPLSFLAREGDRIRLEITNQDSLITDAPMTHF
                     YGQKAGTDTYHHDRLRPSALHLHERPRP"
     gene            complement(2877..3008)
                     /locus_tag="GQF42_RS46275"
     CDS             complement(2877..3008)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GQF42_RS46275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="CocE/NonD family hydrolase"
                     /protein_id="WP_233273581.1"
                     /transl_table=11
                     /translation="MVDVNTAPFETEVRTRAGDLVRADVYLPADSEGPFPVVLGASP"
     gene            complement(3055..3993)
                     /locus_tag="GQF42_RS35495"
                     /old_locus_tag="GQF42_35495"
     CDS             complement(3055..3993)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1066: alpha/beta hydrolase domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019073628.1"
                     /locus_tag="GQF42_RS35495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_35495"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_158926808.1"
                     /transl_table=11
                     /translation="MSGQQRRDLDEMLRHAPLDVGGDVAEARAVFHEMMTSIPLPPDVT
                     TTPGQLGSIPVVTVDTPESDAADVLLYFHGGAYAIGSAADAAGLAADVSRRCSARAVCV
                     DYRLAPENPFPAAVDDAVAAYGALLDQGIPSDRIAFVGESAGGGLTVATLVALRDASLA
                     RPSSATVFSPWADLTVSGASATGKAHLDPALTPQALRTRARDYLGRAAGPEPLASPVFA
                     DLTGLPPLLIQVGSHEILLDDAVRLASRAAEHDVHVELQVWPQVPHVFQSFAVMLDEAD
                     EALRSAAAFVRAHWATTKSPNEAAPVSSLPS"
     gene            complement(4059..4520)
                     /locus_tag="GQF42_RS35500"
                     /old_locus_tag="GQF42_35500"
     CDS             complement(4059..4520)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019073627.1"
                     /locus_tag="GQF42_RS35500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_35500"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_233273824.1"
                     /transl_table=11
                     /translation="MTYLAQPDQQQKLEWLDGGQFAVLLDSAATDGQLTVGRFSVAKGE
                     APPYHMHTREDEIFMLIKGTALLWSDDREMELSEGGIVYLPKNVPHGYRITSDTADLLM
                     ICTPGGIEGMFRHAGRDMSTARPEGFEISTDLMAEAADLYGQIILGPPR"
     gene            complement(4523..4880)
                     /locus_tag="GQF42_RS35505"
                     /old_locus_tag="GQF42_35505"
                     /pseudo=""
     CDS             complement(4523..4880)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016001.5"
                     /locus_tag="GQF42_RS35505"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_35505"
                     /product="nitroreductase/quinone reductase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLLLQTVGARSAAARVSPVMYLADHDRYLVFASEAGSDRNPDWCH
                     NPLARRGGRRRGRRMGRGAARRRARRRVRGAGPPLSRFLRLPAQDASGDPCRRAHPHG"
     misc_feature    complement(4623..4625)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(4875..4877)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            5769..6593
                     /locus_tag="GQF42_RS35510"
                     /old_locus_tag="GQF42_35510"
     CDS             5769..6593
                     /NRPS_PKS="Domain: Abhydrolase_1 (22-127). E-value:
                     7.7e-24. Score: 76.6. Matches aSDomain:
                     nrpspksdomains_GQF42_RS35510_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.5"
                     /locus_tag="GQF42_RS35510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_35510"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_158926812.1"
                     /sec_met_domain="PF00561 (E-value: 7.6e-20, bitscore: 70.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 6e-18, bitscore:
                     65.3, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTRNVQGISLYYESHGDPEAAPVLLVSGLGGVGASWGTQIARFT
                     EKYHVILPDQRGTGRTTRALDGHTTRQLAADMASLVEELDVGPVHVVGASTGGAIAQYM
                     ALEHPRLVRSLTLSSTFARFDAFTRREFEVRRKLAAEWDRHELLSAYSLFLFGPRYARE
                     HPEAVVEWIDRAAALPAHPDDRRIGLARIDMIAAHDTFARLREIAQPTLVLCGEHNFCT
                     PLPLSEELVHGIPDATLAVFEDAGELIELEQPERFFTEVSGFIDGLRDPDRG"
     aSDomain        5835..6149
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GQF42_RS35510_Abhydrolase_1.1"
                     /evalue="7.70E-24"
                     /label="GQF42_RS35510_Abhydrolase_1.1"
                     /locus_tag="GQF42_RS35510"
                     /protein_end="127"
                     /protein_start="22"
                     /score="76.6"
                     /tool="antismash"
                     /translation="PVLLVSGLGGVGASWGTQIARFTEKYHVILPDQRGTGRTTRALDG
                     HTTRQLAADMASLVEELDVGPVHVVGASTGGAIAQYMALEHPRLVRSLTLSSTFARFDA
                     F"
     CDS_motif       6027..6083
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GQF42_RS35510_0001"
                     /evalue="1.30E-05"
                     /label="NRPS-te1"
                     /locus_tag="GQF42_RS35510"
                     /protein_end="105"
                     /protein_start="86"
                     /score="17.8"
                     /tool="antismash"
                     /translation="GPVHVVGASTGGAIAQYMA"
     gene            6605..7423
                     /locus_tag="GQF42_RS35515"
                     /old_locus_tag="GQF42_35515"
     CDS             6605..7423
                     /NRPS_PKS="Domain: Abhydrolase_1 (19-246). E-value:
                     3.2e-14. Score: 45.1. Matches aSDomain:
                     nrpspksdomains_GQF42_RS35515_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012770.5"
                     /locus_tag="GQF42_RS35515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_35515"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_158926814.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3.6e-17, bitscore:
                     62.7, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 2.1e-07, bitscore: 29.9,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLELSDASIFYDDAGEGEPVVFLHGSLCADWLTPMARELTEFRR
                     VVIHRAGYGRSEDRTSGAGVSAQAGHCAAVLTELGLRRAHLVGHSAGADIALHLAYARP
                     DLVVSLVLLEPALPRADDEPASPAMPAAIAAARTGAWEAAFYAFLTGVCGPGVRSLFAE
                     RLGEQGLAEAVDSSRYFFTRESAAFGGWEFGARQMSAVQAPTLLVVGGGGDRLGTPHRA
                     RAASIAAHLPHAETLVVDGLTHAMPLEDPVLMARIVSEFVTSHPLSDSTG"
     aSDomain        6662..7342
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GQF42_RS35515_Abhydrolase_1.1"
                     /evalue="3.20E-14"
                     /label="GQF42_RS35515_Abhydrolase_1.1"
                     /locus_tag="GQF42_RS35515"
                     /protein_end="246"
                     /protein_start="19"
                     /score="45.1"
                     /tool="antismash"
                     /translation="PVVFLHGSLCADWLTPMARELTEFRRVVIHRAGYGRSEDRTSGAG
                     VSAQAGHCAAVLTELGLRRAHLVGHSAGADIALHLAYARPDLVVSLVLLEPALPRADDE
                     PASPAMPAAIAAARTGAWEAAFYAFLTGVCGPGVRSLFAERLGEQGLAEAVDSSRYFFT
                     RESAAFGGWEFGARQMSAVQAPTLLVVGGGGDRLGTPHRARAASIAAHLPHAETLVVDG
                     LTHAM"
     CDS_motif       6857..6904
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GQF42_RS35515_0001"
                     /evalue="6.80E-04"
                     /label="NRPS-te1"
                     /locus_tag="GQF42_RS35515"
                     /protein_end="100"
                     /protein_start="84"
                     /score="12.2"
                     /tool="antismash"
                     /translation="HLVGHSAGADIALHLA"
     gene            complement(7389..7745)
                     /locus_tag="GQF42_RS47785"
                     /old_locus_tag="GQF42_35520"
     CDS             complement(7389..7745)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013224.5"
                     /locus_tag="GQF42_RS47785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_35520"
                     /product="Lrp/AsnC ligand binding domain-containing
                     protein"
                     /protein_id="WP_407699510.1"
                     /transl_table=11
                     /translation="MAHHGIDELLAAGTALAASPEVAFAAGVTGASNLFAGVSTPDTSA
                     LWQFLTSFVGRLPGVRDVETVTALRPVKGAVAFFPRPPTRASRHASPRAGSPRGPAATV
                     TRCFNRSSRTAGGS"
     gene            complement(<8063..8437)
                     /locus_tag="GQF42_RS47790"
                     /pseudo=""
     CDS             complement(<8063..8437)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013676.5"
                     /locus_tag="GQF42_RS47790"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="Tn3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDLRAEAGRAHRPAALKDEVVRRWGVLDLLDVLTNADFDAGFTDE
                     FASVAGYDRIDRAVLQRRLLLALFALGTNMGIRAIVATGEHGESEAALRHVRRHFITVD
                     NLRAAVRKLVNATFAARDTAW"
     gene            complement(8338..8808)
                     /locus_tag="GQF42_RS45135"
     CDS             complement(8338..8808)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GQF42_RS45135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_199272910.1"
                     /transl_table=11
                     /translation="MNSTPVLLPPSGASPASTRPRAITHSCHSCSAHNSYGGAVGIYDV
                     GLTEYRNFRIATLRQWDDLPGDFEATRTVHYAAIRQPLNVREFITDLKQRMASGRDRLT
                     AALADGSSGGVKVITRHGEPWISVPKLDGPTGQQRSRTRWCAAGVCSTSWTC"
     gene            8931..9539
                     /locus_tag="GQF42_RS35530"
                     /old_locus_tag="GQF42_35530"
     CDS             8931..9539
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014151647.1"
                     /locus_tag="GQF42_RS35530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_35530"
                     /product="hypothetical protein"
                     /protein_id="WP_158926816.1"
                     /transl_table=11
                     /translation="MLTVVQVLGMSSEDEMVACFLSGELSSQRFGQNLRSHLAAAGQAE
                     QLLTHPDLSDAGANFARRALLAATRGYGENRDLFENFPTEVTWTRALLSADEAASVRYL
                     KYSYWVELSGGSRRPTDAAARIKAGLRAFDVSNEPFVDAAQALIRGERFPPLILVGEKR
                     DNLVCLEGHLRLTVYAIVGFPTDIECLIGTAPTMGRWAQ"
     gene            10001..11065
                     /locus_tag="GQF42_RS35535"
                     /old_locus_tag="GQF42_35535"
     CDS             10001..11065
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014141236.1"
                     /locus_tag="GQF42_RS35535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_35535"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_233273582.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.9e-44, bitscore:
                     150.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVDAQAIDLRVVQRQVDGVLEDFLSEKARAATGRGHPPEVVQSVR
                     DFLAAGGKRIRALLCVVGWHAAGGQGDAASAVRVAASLELFVAFALIHDDIMDDSASRR
                     GRPAVHRVMRAQLGGGERAERLGAGGALLVGNLALTWAQELLHTARLEPGRQRLVHGLY
                     DAMLEEVMYGQYLDVMGTGRGADDIEAALRIIRYKTATATIERPLQLGAAVAGAGEAVM
                     DTFTRLGLPLGEAFQLRDDLLDVFGSPDGACAPGLSDLREGKRTVLLALGLGLADPVQR
                     ERLGHLVGRAALEEREAAEVRDILQVTGAREQTERMIASRYEHVLRVLDQAGFPQAADR
                     ALRGLAAKATQYTS"
     misc_feature    10823..10825
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11152..12222
                     /locus_tag="GQF42_RS35540"
                     /old_locus_tag="GQF42_35540"
     CDS             11152..12222
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978295.1"
                     /locus_tag="GQF42_RS35540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_35540"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_158926818.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.6e-42, bitscore:
                     144.5, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEQVMQRVAEYERRFNTLFEEYFDTLSARLDVPSLSRFTPDCVE
                     LLWDVSLRGGKRFRVVALNEAARLVTADPVEGLDAAALSVELLQTSGLVHDDVIDDGPV
                     RRGGPSTYYAYRERFPEHPHTAVGLTVLAGDLALVMSLQVLLESKAPMGVRQAMVEVQT
                     RAAADTFMGQIIDVERDFMTTPDEDVLHCVADYKTARYSILAPMQLGLLAAGEQPSLFE
                     EELRDYARLVGISETMRDDYLDLFGEAARLGKPTGADIRDGKHSYTVNALLAAITGPER
                     RTVEAALGDSSCTPETIAAIREIGERRGVADQMQAYMRRYAQQASAVAAGWRSRWREEA
                     VAFFEQLPLWSVERAR"
     gene            complement(13555..14073)
                     /locus_tag="GQF42_RS35545"
                     /old_locus_tag="GQF42_35545"
     CDS             complement(13555..14073)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003959587.1"
                     /locus_tag="GQF42_RS35545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_35545"
                     /product="hypothetical protein"
                     /protein_id="WP_233273583.1"
                     /transl_table=11
                     /translation="MLILAPLLGWHADGWAGLGWGLFAALFTAVLPTLILRFGERRRYW
                     GDRHVRRRQDRIVAAPGVMGSVLTGSALLYALDAPAAVVALVTAMVAVLLALLMITFFW
                     KVSVHSAVASGALAILVTGFGPWMLVLAPLVVLIGWSRVRLHCHTVGQVAVGMLIGAAV
                     STPLYTFLG"
     gene            complement(14306..15121)
                     /locus_tag="GQF42_RS35550"
                     /old_locus_tag="GQF42_35550"
     CDS             complement(14306..15121)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GQF42_RS35550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GQF42_35550"
                     /product="ABC transporter permease"
                     /protein_id="WP_158926820.1"
                     /transl_table=11
                     /translation="MTRWWSCFRTALRFALIEQARNRLALLIVVLFVPLWTTLAFTVVP
                     STPLRFRIRSIGRTVVMDGNILLQINGALQALSLVIAFMMFVATARSALFDQRLARAGY
                     PRSCLAIAKCTALLLVAALVAAYTTAWMHLFWRPEQPLVLAAGMFTGALVYGGIGIVLA
                     AVVRSELAGMFLAIMISSIDLVLQNPLINPDADSLVVRFLPAYAAVQTSVTAAGLQVVP
                     VTGLLLGGGWAVGMAALGLAAFTARTRSRQSRAATRKETASVEQGALVP"
     gene            complement(15118..15738)
                     /locus_tag="GQF42_RS35555"
                     /old_locus_tag="GQF42_35555"
     CDS             complement(15118..15738)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891590.1"
                     /locus_tag="GQF42_RS35555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_35555"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_233273827.1"
                     /transl_table=11
                     /translation="MDVRDVRKGYRDRPVLRGVFLDLCPGQLVGIVGENGAGKSTLLRI
                     LAGDLAADSGTVERAGRLGCCPQGTVLHQAFTVEQHLQFFQAAYGISHLTRAYELLEEL
                     NFSDYRHEPVAALSGGTRQKLNLVLALMHDPQVLLLDEPYQGFDWETYLRFWDLAAALR
                     DRGCAVLVVSHLAYDASRLDILYRLQAGVLLQTEQTEAGRAAV"
     gene            complement(15911..17155)
                     /locus_tag="GQF42_RS35560"
                     /old_locus_tag="GQF42_35560"
     CDS             complement(15911..17155)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014668672.1"
                     /locus_tag="GQF42_RS35560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_35560"
                     /product="hypothetical protein"
                     /protein_id="WP_233273584.1"
                     /transl_table=11
                     /translation="MHDLLTNTAGEVPAGLAALEAVLTDVTNPYPVLEWIRRSPAARLL
                     ARLAQAADPLTHQALDALPPDANTAYVRGLLVTAGVLPQRQENLARLEIWLTGKLARLP
                     AHHVTLIRPFAEWGIVKDARRRAARGRYSLAAFKGDCTGIRVTIRFLAWLDDQDLHVRD
                     LSQAHLDDWTSTHATQRTCLIPFVRWAHARHIVRDLEIHHRPTQAPGTFQDETTHQAEL
                     RRCLTDTELPLHVRIIGALVRLYALPLTRIVELTTDQFHQDAEAHPVLLPPAPARLLDE
                     QITNPGEALTPSGQRLLLPGVVPGRPRNPAGLADQMRQHGLPVRAARNTALMEAITDLP
                     PIVVADLFGISPATAQRWSQLAGNRRRGRKRGSSQIPGRVDERTVRVCVSEALGNSGSS
                     MIARGGSDCLIGRVL"
     gene            complement(17622..17837)
                     /locus_tag="GQF42_RS45140"
     CDS             complement(17622..17837)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GQF42_RS45140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_199272911.1"
                     /transl_table=11
                     /translation="MAGALEGTALYPVVGEQTLRGLVAEAKANEKVFKAKVRTTLRSSY
                     SSYYRQMLPPLLRTLGFRCNNTAYGL"
     gene            complement(18544..19614)
                     /locus_tag="GQF42_RS35570"
                     /old_locus_tag="GQF42_35570"
     CDS             complement(18544..19614)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GQF42_RS35570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GQF42_35570"
                     /product="hypothetical protein"
                     /protein_id="WP_158926822.1"
                     /transl_table=11
                     /translation="MAKLSTKFVRIYAGTVAAVAVSGIGYSASASAATPPATVPAGFST
                     TVFAHAGGKLTGADDIARLGDKLFVGYQNGVGSKGEPAANGTKSSTVVEFDRHGKEVAH
                     WDVAGKVDGLGADKRTGQIVATVNEDGNSSAYTVDPDSKHHAVRHYHFSSLPHGGGTDN
                     VSVRHGVVYIVASNPTADAKGSTAGRPALYKVTFHGTTAKTTPVFDDNITATNLVTGKT
                     GALNLTDPDSSTFVPRSVPSLGGSLLLDGQGDQQAVFVKNWGTKKQRAHVLPLSQQVDD
                     TAFATSTEGTLYVVDSAKSEVIAVTGHFTRGEAFVSAKGGLGTLSLKTGTVTAFGNAVS
                     SPKGLLFVAAERDERK"
     gene            complement(19972..20175)
                     /locus_tag="GQF42_RS35575"
                     /old_locus_tag="GQF42_35575"
     CDS             complement(19972..20175)
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1255: cold-shock
                     DNA-binding domain protein"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020120296.1"
                     /locus_tag="GQF42_RS35575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_35575"
                     /product="cold-shock protein"
                     /protein_id="WP_158926824.1"
                     /transl_table=11
                     /translation="MAKGTVKWFNAEKGFGFIEQEGGGPDVFAHYSNIATEGFRELREG
                     QHVEFDVTQGQKGPQAENIRPL"
     gene            20478..20690
                     /locus_tag="GQF42_RS35580"
                     /old_locus_tag="GQF42_35580"
     CDS             20478..20690
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006124546.1"
                     /locus_tag="GQF42_RS35580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_35580"
                     /product="hypothetical protein"
                     /protein_id="WP_158926826.1"
                     /transl_table=11
                     /translation="MAERRVIVFPPGEGGGRRVQVDSETLGTAHSLHDLSVFLERAGLE
                     GLDVVDLVNSPLIEWLGGGPEVWEH"
     gene            20829..21020
                     /locus_tag="GQF42_RS35585"
                     /old_locus_tag="GQF42_35585"
     CDS             20829..21020
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GQF42_RS35585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GQF42_35585"
                     /product="hypothetical protein"
                     /protein_id="WP_158926828.1"
                     /transl_table=11
                     /translation="MDQGKIHEWDADPGEGSIKSDRGGPVLYFTVDDLMIDPGEIHQGD
                     TVSFRVEGPGKAAMVNKA"
     gene            complement(21234..21737)
                     /locus_tag="GQF42_RS35590"
                     /old_locus_tag="GQF42_35590"
     CDS             complement(21234..21737)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006376749.1"
                     /locus_tag="GQF42_RS35590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_35590"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_407699511.1"
                     /transl_table=11
                     /translation="MDELVERVDDQDRVLGVVVSRRQAIREGWLHRVAVTVCRDERGRI
                     LVHRRSEQLSRFPGFYEVVVGGAVDIGESYEKAAARELAEELGTRVLPRLLFTFINRSG
                     LSPHWLGVHEAVVPDAVVPDPDEVAWHAWLTEPELRSALLEWCFTPDSHEAFSRYLAFR
                     TAQS"
ORIGIN
        1 cccgtcgcct gctgggctgg tcgatggccg atcacatgcg ggccgagctc gtcaccgacg
       61 cgctcaacgc ggccgtccgc actcgcggcg cccaggtgga cggcgtcatt ttccacagcg
      121 atcacggggc tcagtacggg tcgaaggcgt tcgtcgatgc ctgccgccag gccgggatcc
      181 ggcggtccat gggagcagtc ggcacctccg cggacaacgc cgccgcggag tcgttcttcg
      241 cctcactcaa gcgggagaac ctgtccgacg aggcgacaca ctccaaggtc accacgctgc
      301 gggggaacgt cgaaccgggc tcgaaggccc agatcgaaaa tggcttcctg gggcagtgga
      361 tcaatccaac taccggtaaa cgaaaccgaa tttggtcgtt cgtgatggtg ctgcccacct
      421 cgtggcccca cttcatcccg acctaccgac gagttcgacg aactacaggt gagagtcggc
      481 gcgtagagcg tccagcttct cggcgtcatc ggttccggca acggccgtgt aggcgacgat
      541 acggagatcc gagccgggga ccatgaggac gtcgaggtcg agggtcaggt cgccgacctt
      601 gggatgttcg attgtcttgc ggtcgccggt gtggaggccg gcagtgccgt tggaccacag
      661 gtgggcgaag cgggggctgg tgtggagcaa ccggtcgacg agcgaggtga ggcgggcgtc
      721 gtcggggtag gccgctgccg tgacccgcag atcggcgacg agggcctcct cctcgtcctc
      781 gtcgcccgcc caggaccgta ctggccaggc ggcaatcgaa tcgactcggc gaccgtcgct
      841 ggagcggaac atcccggcga cgagattgcc ctggtcccag ccgtaggtaa gggggtcacc
      901 gatggcggcg gtccacatcc ggttccagct gaccagcgtc cagtcggcgg cgtagaccgc
      961 gacaggcgcg tcgcccatgt gccggacgag ccggtggacg ctcgacggca cgtgcagtga
     1021 cacgtcgccg ttggatggcg gcgcgagatg ggcacagcgg aacaggtggt cacgctcgga
     1081 ggtgcccagg tgcagggctc tggccagggc ggtgacgacc tgggcggagg gattgcgggc
     1141 gcggccctgt tcgagccgca ccacgtagtc gaccgacagg ccggccaggc cggcgagttc
     1201 ctcgcggcgc agaccgggaa tccgccggtg ggcgtcggat tccagcccgc ccgccaaggg
     1261 cgagaagcgc tcccgccagc ctcgcagggc gatgccgaag ttgttcgtca tggccatgcg
     1321 gtcatcatcg ttcaggtgcc ccgcccgcag cagtcctcct ttcccacatc tgggcaaaac
     1381 cgtcaggggc gcgggcgctc gtgcaggtgc agcgccgagg ggcgcagccg gtcgtggtgg
     1441 taggtgtcgg tgccggcctt ctggccgtag aagtgggtca tgggagcgtc ggtgatcagc
     1501 gagtcctggt tcgtgatctc caggcggatg cggtcgccct cgcgggccag gaacgacagg
     1561 gggagcagtt cgatgtggag ttcgtagacc ttgccgggct ccagcggatc cacgccgttg
     1621 tgcaggtgga acggacgcat gtcactggtg agttcggggt cctcggcgcg gtgggaggca
     1681 cgtagccagc cctggctgac cttgatcggc agcttcgcgc cggagttgct ggggatgagg
     1741 gagaccttga cgatgacgtc catgtcggtc tggtccgtgg aggcgtgcag ggtcagcgtg
     1801 gcatggccgg tgaactcgcg gtccttgtcc atgggagcgg tggtgaaggt gttgacccgc
     1861 gcgacgtggt cggggacgcc gtgcttgtcg aagaccgtga cgccggccat ccactcggga
     1921 tccgggtagg accaggaggt ggacgcctcg tccgccaccg gcttggtctc ggtgagcgtt
     1981 ccgtcgttga gggagtcgac ggcgccgctg tgctccccgg cgaggtagaa ggtgctggtg
     2041 cgcacgtccg gtggcggcca ggagggcgcc gagtggtagg cgtcctcgcc gttgacgtag
     2101 aaacggatgt tgggcttttc catcacgccg ttgtcggtgc ccttgaggtg gtggtcgtac
     2161 caggggagca actcagtgcg gtggaagtcc tcgtcgaagt agtacctctg cgcggcggcg
     2221 aagctgccgg ggtgcgtgac cagcagcttc ttgggccccc gtacgcgctc gaagccgtag
     2281 aagttgccac gcaggtgcag cgccgccttt ccccacacgc cgatggagaa cacggggatg
     2341 tcgatctgtg gcaactccca gaacggcgag cgccgacgat gccattcgtc gtccacgggg
     2401 tgggagagga tgtcgtagac gaagtcctgc ttgccgccga cgcggaagcc gatgccctcg
     2461 atctcgtgct ggaccagcac cgagccgaac agccaggtgc tcaggaagcc ctggatcggg
     2521 atgcccccgt ggtacatcca gtcgcggtac atgtcggtgg cgccgtcgta ggcgacgatc
     2581 gtcctcagat gcggcgggcg ggtgcgcgcg gcgttccact ggctccagca gtagtgggac
     2641 atgccgatca tgccgatcgc accggtcgac cacggctcgg cagcgacgtg ctcgatcatg
     2701 tcgtggatgg cctcgccctc gccgcgggag accgggtccc aagtgccctc ggagcggccg
     2761 gttccgggta cgtccatcac gacgtaggcg tagccgttgt tgaggtagag ctgtatgggc
     2821 ccgtattcga tgaacgggaa caccgggtgt gccggcaggt ggcgcagcgc cttctgttac
     2881 ggggaggcgc cgagaacgac cgggaacggc ccctcgctgt cggcggggag gtagacatcg
     2941 gcgcggacga gatctcccgc gcgggtgcgg acctcggtct cgaagggggc tgtgttcacg
     3001 tcgaccataa cggttcttct ccaagccttt ccggagtgcg gaagacagtc gcggtcacga
     3061 cgggagcgag ctgaccggcg cagcctcgtt ggggctcttg gtggtggccc agtgggcccg
     3121 gacgaaggcg gcggcggacc gcagtgcctc gtcggcctca tcgagcatca cggcgaacga
     3181 ctggaagacg tgcgggactt ggggccagac ctggagttcg acatgaacgt cgtgctcggc
     3241 agcgcgggag gccagtcgta cggcgtcgtc caggaggatc tcgtgcgagc ccacctggat
     3301 gagcagcggt ggcaggcccg tcaggtcggc gaagacagga ctggccagtg gctcagggcc
     3361 ggccgctcgc ccgaggtagt cgcgggcgcg ggtgcgcagt gcctgcgggg tcagtgcggg
     3421 gtcgaggtgg gccttgccgg tcgcgctggc gccggacacc gtgaggtcgg cccacggcga
     3481 gaacaccgtg gcggacgagg gccgggccag gctcgcgtcc ctgagggcga ccagcgtcgc
     3541 gacggtcaga ccgccgccgg cggattcgcc gacaaaggcg atccggtcgc tggggatgcc
     3601 ctggtcgagc agcgcgccgt acgcggccac ggcgtcgtct acggccgcgg gaaacgggtt
     3661 ctcgggagcc agccggtagt cgacgcagac ggcacgggcg ctgcagcgcc gggacacgtc
     3721 ggcggccagg cccgccgcgt cggccgccga accgatggca tacgcgccgc cgtggaagta
     3781 cagcagcacg tcggccgcat cgctttcggg agtgtcgacg gtgacgacgg ggatgctgcc
     3841 gagctgcccg ggggtggtcg tgacatcggg aggcagtgga atcgaggtca tcatctcgtg
     3901 gaagacggcg cgtgcttcgg ccacgtcgcc tccgacgtcg agcggagcgt gccgaagcat
     3961 ctcgtcgagg tcgcggcgtt gctgcccgga catggctgtg cctttcgtgc ggttcgtacg
     4021 ggatgggcgc ttggttggag cggtcggtgt gccggcactc agcgcggcgg gccgaggatg
     4081 atctggccgt acagatcggc ggcctccgcc atcaggtccg tggagatctc gaacccctcg
     4141 ggccgggcgg tcgacatgtc gcgcccggcg tgccggaaca tgccctcgat gccgccggga
     4201 gtgcagatca tcagcaggtc cgcggtgtcg gaggtgatcc ggtagccgtg ggggacgttc
     4261 ttgggcaggt agacgatgcc gccctccgac agctccatct cccggtcgtc cgaccacagc
     4321 agcgcggtgc ccttgatcag catgaagatc tcgtcctcac gggtgtgcat gtggtagggc
     4381 ggtgcctcac ccttggcgac gctgaaccgt ccgacggtca gctgtccgtc agtggccgcg
     4441 ctgtccagga gcacggcgaa ctgaccgccg tcgagccatt cgagcttctg ctgctgatca
     4501 ggctgcgcga ggtaggtcat gctcacgacg atgtccgttc tgtgcagtcg gcgggtgccg
     4561 ggccgccctc acccgtgagg atgagcgcga cgacagggat cacccgatgc gtcttgcgct
     4621 ggtaaccgga gaaaccggga tagcggcggg cctgctccgc gaacgcggcg tcgtgctcgg
     4681 cgccgcgcag ctccacggcc catgcggcga ccacgtcgtc gcccacctcg acgcgcgagc
     4741 gggttgtggc accagtccgg attgcgatcg gagcccgcct cggaggcgaa gaccagatag
     4801 cggtcatgat cggccaggta catcaccgga ctcacccggg ccgcggccga gcgtgctcct
     4861 acggtttgca gcagtaacac cgggcccggc gaaacccccg ctcagccgcc cgtgatgcgc
     4921 acggaactcc tcgatattgc gtgcgttgaa agcggtggta tcagccatca cttctccggt
     4981 gcgagacgag gtcgggtggc ctgacggacg ggcggtgtgc tctgcccatg ccacctcggg
     5041 cccggacggc cgtggccggc gaccttcggc gggtcgcctc ccacgagtga tgatgcgctt
     5101 ccggaagcgg ccaccgccag aggcgtggat aggaccagca gtaccaccgt ctgctggtgg
     5161 tcgattgctc ggttggttcc cggttggtcc tcgaataatc cgaggagaaa gtcctgactt
     5221 gacttcagga gagcctgcga cgtcagcgga cggggctgcg tgcagggatg ggttgtggct
     5281 gccgccaggc tcggcggcgg acgcgcagaa gccgttccgg aaggtgcgtt tgccggggcg
     5341 gccgcgcccg tcgtaccgcc gggcgccgtc ggagccgcgg cgccgccctt ccgcttgcgg
     5401 cgtggggcgg ggagcgtgag cgcgtcggcg gtcaggcggg gcagcgtaga gcagggttgc
     5461 ctgaggaagc cctggacgcg ggcggcctcc gtgcggagcc gttgttcgga gcagccgtgg
     5521 aggagggggt aggtcagtga ggtcgccggg tccttgtagt caggctcgga gaggggggca
     5581 gcacatcgca tgggcgagat cgaggtacgc cagcttcact ggtcggcggc gagtgtgtcg
     5641 ctttttgccc atcgatagca aacagctgtc ggatatcgct caaactgacg gtccaagggt
     5701 ggcataccgg tggacgagtg cttgcctcgt gtcgaaggaa cagcaggcaa gacgcaaggg
     5761 acagcagcat gagcactcgg aacgtgcaag gtatttctct ctactacgag agccacgggg
     5821 acccggaggc cgcgccggtt ctgctcgtct ccggtctggg tggggtgggc gcgagctggg
     5881 ggacgcagat cgcccgcttc accgagaagt accacgtgat cctgccggat cagcggggca
     5941 cagggcgtac aacccgggcc ctcgacggcc acaccactcg gcagctcgcg gccgacatgg
     6001 cctcgctcgt cgaggaactc gacgtcggcc cggtccatgt cgttggcgcg tcgacgggcg
     6061 gcgccatcgc gcagtacatg gcgctggaac acccgaggct tgtgcgctcg ctgacgttga
     6121 gttcgacgtt cgcgcgcttc gacgccttca ccaggcgtga gttcgaggtg cggcgtaagc
     6181 tcgccgccga gtgggacagg catgaactgc tgtccgccta ctcactgttc ttgttcgggc
     6241 cgcggtacgc ccgtgagcac cccgaggccg tcgtggagtg gatcgaccgc gcagccgcgc
     6301 tcccggccca ccccgacgac cggcggatcg gcctggcgcg gatcgacatg atcgcggcac
     6361 acgacacgtt cgcacggctc cgcgagatcg cccagccgac actggttctg tgcggcgagc
     6421 acaacttctg cacgccgctt ccgctgtcgg aggagctcgt gcacggcatc ccggacgcca
     6481 cgctggccgt cttcgaggat gcgggcgagc tcatcgaact ggagcagccg gagaggttct
     6541 tcacagaggt gagcggcttc atcgacgggc tgcgcgaccc ggaccggggt tgaggtgtgt
     6601 ggagatgaga ctcgaactat ccgatgcctc catcttctac gacgacgccg gcgagggcga
     6661 acccgtggtg ttcttgcacg gttcgctgtg cgccgactgg ctcaccccca tggcgcgcga
     6721 gctgacggag ttccgacgcg tcgtcatcca ccgtgccggc tacggccgca gcgaggaccg
     6781 cacgagcggg gccggcgtgt ccgcgcaggc cggccactgt gccgcggttc tgacggagtt
     6841 ggggctgcgg cgtgcccact tggtggggca ctccgccggg gccgacatcg cactgcacct
     6901 ggcctacgcc cgaccggacc tggtcgtctc gctggtcctc ctggagcccg cgctgccccg
     6961 ggcggacgac gagcccgcga gtccggcaat gccggccgcg atcgccgcgg ccaggaccgg
     7021 tgcatgggaa gcggccttct acgcctttct caccggggtg tgcgggccgg gcgtacgcag
     7081 cctgttcgcg gaacggctgg gagagcaggg gctcgccgaa gctgtcgaca gcagccgtta
     7141 cttcttcacc cgggaatcgg ccgcgttcgg cggctgggag ttcggtgcac ggcagatgag
     7201 cgccgtgcag gcgccgacgc tgctcgtcgt cggaggcggg ggcgaccggc tcggcacgcc
     7261 ccaccgggcg cgagccgcct ccatcgccgc ccaccttcca cacgccgaga cgctggtcgt
     7321 cgacggcctc acccacgcca tgccgttgga ggatcccgtg ttgatggctc gcatcgtcag
     7381 cgagttcgtc acgagccacc cgctgtccga ctcgaccggt tgaagcaccg cgtcaccgta
     7441 gcggcaggtc cgcgcggtga cccggctcgg ggcgacgcat gccgggacgc gcgtgtcggc
     7501 ggacggggga agaaggcgac ggcgcctttg accgggcgca aggccgtcac cgtctcgacg
     7561 tcccgcacgc cgggcagtcg ccccacgaat gacgtcagga attgccacag cgcggacgtg
     7621 tccggcgtcg agacgcccgc gaacaggttg ctggccccgg tgacccccgc tgcgaacgcc
     7681 acctcgggac tggcggcgag cgcggtgccc gcggcgagga gttcatcgat cccatggtga
     7741 gccacaacat ggtgcgcact ggcacgtcga agacggcgag gtcgacatcg acgtcgaagt
     7801 gcaggacacc ggcggcccga aactcgtgca gtcgacggcg gacagtgctc gccgatgcgg
     7861 cgccgtggca gccatcagct cgtcgatcga cgttcgtccg tcggctcgca gcacctcgag
     7921 catgcggcgg ctggtcccat ccatcttcgg aggctgtccg accacgggag gagcatgccg
     7981 ggccaccaag gcccggaccc caacggggtt tccaggaccc gaacttcttc gagtccgaca
     8041 cgcacgcggt tccctggccc caccatgcgg tgtcccgggc ggcgaaggtg gcgttcacca
     8101 acttccgcac ggcggcccgc aggttgtcga cggtgatgaa gtgccggcgc acgtgccgca
     8161 gcgccgcctc gctctcacca tgctcgccgg tcgccacgat ggcacggatg cccatgttcg
     8221 taccgagggc gaacagggcc aagaggaggc gtcgctggag gacggcgcgg tcgatgcggt
     8281 cgtacccggc gaccgaggcg aactcgtcgg tgaaaccggc gtcgaagtcg gcgttcgtca
     8341 gcacgtccag gaggtcgagc acaccccagc ggcgcaccac ctcgtccttg agcgctgctg
     8401 gccggtgggc ccgtccagct tcggcacgga gatccacggc tcaccgtgcc gggtgatcac
     8461 cttcactccg cccgacgagc cgtccgccag cgcggccgtg agccggtccc ggccgctcgc
     8521 catccgctgc ttcagatccg tgatgaactc ccgaacgttc agcggctgac ggatcgccgc
     8581 gtagtgcacg gtgcgggtgg cctcgaagtc gccgggtaga tcgtcccact ggcgaagtgt
     8641 cgctattcga aagttgcggt attccgtcag accaacatcg tagataccga ccgcgcctcc
     8701 gtagctgttg tgggccgagc aggagtggca ggagtgggtg atcgcccgcg ggcgggtcga
     8761 tgcggggctg gctccagacg gcggcagcag caccggtgtg gagttcaccc tggatgtgag
     8821 aggacgttct gaaccgcttt acccggttcg accgctggct tgtgtcaggt gggctggtgg
     8881 cgcggagcga cgggttaccc gggcgccgcc aggcgaacga ggtcgaccct atgctgacgg
     8941 tcgtgcaggt actgggcatg agcagtgagg acgagatggt cgcctgcttc ttgagcggcg
     9001 agctgtccag ccagaggttc ggccagaacc tccggtccca cctggcggca gccgggcagg
     9061 ccgagcagtt gctgacgcat ccagacctct ccgacgctgg agcgaacttc gcacgtcgtg
     9121 ctctgctcgc tgcgacgcgc gggtacggcg agaaccgcga cctgttcgaa aacttcccca
     9181 ctgaggtcac ctggaccagg gcactcctgt ccgccgacga ggcggccagc gtgcgctacc
     9241 tcaagtattc ctactgggtc gaactgtcgg gtggcagccg ccggccgacc gacgcggccg
     9301 cacgcatcaa ggcagggctg cgggcgttcg acgtgtccaa cgaaccgttt gtcgacgcag
     9361 cccaggcgct catcagaggc gagcggtttc ctccgctcat cctcgtcggc gagaagcggg
     9421 acaatctggt ctgccttgag ggccacctgc gcctgaccgt ctacgccatc gttggcttcc
     9481 cgaccgacat cgagtgcctg atcggcaccg cgccgaccat gggacgctgg gcgcagtagt
     9541 ccagtcacac caagctctcg gcgcactaaa tgaaccttag gagaggttct gatccgctct
     9601 tggccgattc ggctgttggc tcgggtcatc aggtgggctg atggcgcgga gcgagtgatc
     9661 cggatctcct cggcggccct gcgtctgttc ggtgtagaaa cggccatgca gtacgtcgcc
     9721 gccgcgtacc cggacctccc ggctcccccg ctgatcggcc ctcccgggag tgtccgaagg
     9781 cgacgtcgag tccccacgca agcacgtcgc gtcgcgcgtg ttcttcagcg gtctgggtcg
     9841 ttggacggat catgcagacc aaatgggtga cgtggccagc cagtggcccc gggtgtcatc
     9901 agcgccctgt cacagggtgc ggccataacg atcacctccc ctccgtcccc gctgggccgg
     9961 aatctgcccg cttgggagtg gtgaatcggt gacctcgagt gtggtcgacg cacaggcgat
    10021 tgacctgcgt gtggtgcaac gccaggttga tggagtgctt gaggactttc tgtctgagaa
    10081 ggcccgggcg gcgactggcc gggggcatcc gccggaggtc gtgcagagcg tccgcgactt
    10141 cctggcagcc ggcgggaagc gaatcagggc actgctgtgt gtggtgggct ggcacgccgc
    10201 cggcgggcag ggggatgcgg cgtcggcggt gcgggtggcg gcgtcgctgg agctgttcgt
    10261 ggccttcgcc ctcatccacg acgacatcat ggacgactcg gccagccgcc gaggccggcc
    10321 cgcggtccac cgcgtgatgc gagcccagct gggaggcggc gagcgagctg aacggctggg
    10381 cgcgggcggc gcgctgctgg tgggcaacct cgcgctgacg tgggcgcaag agctgttgca
    10441 cactgcccgg ctggagcccg ggcggcagcg gttggtccac ggcctgtacg acgcgatgct
    10501 ggaggaggtg atgtacgggc agtacctgga cgtcatgggg accggccggg gcgccgacga
    10561 catcgaggca gccttgcgga tcatccgcta caagaccgcc accgcgacga tcgagcggcc
    10621 cctgcagttg ggggccgccg tcgccggggc cggtgaggcc gtgatggata ccttcaccag
    10681 gctgggtctg ccgctgggtg aggcgttcca gctgagggat gacctgctgg acgtcttcgg
    10741 cagcccagac ggcgcgtgcg cgcctggcct gagcgacctg cgagagggca agcggaccgt
    10801 cctgctggcc ctgggactgg gattagccga cccggtccag cgggaacggc ttggccactt
    10861 ggtgggccgc gccgccctgg aggaacgtga agcggcggag gtccgggaca ttctgcaggt
    10921 gaccggggcg cgggagcaga ccgagcggat gatcgcgtcc cgctacgaac atgtgctgcg
    10981 cgttctggat caggctggct tcccgcaggc cgcagatcgc gcgctgcgtg gcctggccgc
    11041 caaggccacc cagtacacct cctgacacca cgcggcctgg agccgtcagc accaccgtcg
    11101 ctggcgcacg gccacgacta tgccgtccga cctgaacaga gagaacgctt gatgaccgag
    11161 caggttatgc aacgcgtcgc cgaatatgag cgccgcttca acacactctt cgaggagtac
    11221 ttcgacacgt tgagcgcgcg gctggacgtg ccgtcgctca gccgtttcac cccggactgc
    11281 gttgagttgc tgtgggacgt ctccttgcgc ggcgggaagc ggttcagggt cgtggcactg
    11341 aacgaggcag ctcgcctggt gaccgccgac ccggtcgaag gactggacgc tgcggcgctg
    11401 agcgtcgagc tgctgcagac ttccggcctg gtgcatgacg acgtcatcga tgacggtcct
    11461 gtccgccggg gaggcccgtc cacttactac gcctaccgcg agcggttccc cgaacacccg
    11521 cacacagccg tcggtctcac cgtgctcgcg ggtgacctcg cactcgtgat gtccctgcag
    11581 gtgctgctgg agtcgaaggc gccgatgggg gtgcggcagg ccatggtcga ggtccagacc
    11641 cgggccgcgg ccgacacgtt catggggcag atcatcgacg tcgagcggga cttcatgacc
    11701 accccggacg aggatgtcct gcactgcgtg gccgactaca agacggcacg ctactcgatc
    11761 ctcgcgccca tgcagctggg actgctggcc gcaggggagc agccctccct ctttgaggaa
    11821 gagctgcgtg actatgcgcg gctggtcggg atcagcgaaa cgatgcgcga tgactacctg
    11881 gacctgttcg gggaggccgc ccgcctgggc aagccgacag gcgccgacat ccgcgacggc
    11941 aagcacagct acaccgtcaa cgccctgctg gcggccatca ccggcccgga gcgtcgcacg
    12001 gtggaagcgg cgctcggtga ttcgtcctgc acgccggaaa ccatcgccgc catcagggag
    12061 atcggcgaac gccgcggcgt ggcagaccaa atgcaggcct acatgcgccg ctacgcgcag
    12121 caggcgtccg cggtggcagc cggctggcgg tcgcggtgga gggaggaggc ggtcgccttc
    12181 ttcgagcagc tgccgctgtg gagcgttgag cgagccaggt gaccagcgac cgcaccactg
    12241 gcgtgatgcg cccggccggt gtgcaccgcg tggatgcggg atcgtcgccc gcggtcggcg
    12301 gggctgcggc tgccaggtcc gccagtgcct gctgccagag ttcggggagg ctgtcggcgt
    12361 cggggagtgc ggtgtcgatg cggaagcacg cgctggttgt gtcgccgtat gccgtcgcca
    12421 cgacagcgat ggggacaccg ggcgggcagc acatgatggg gtcgatgcga tgcacttccg
    12481 cctcgccgta gtgcagccgc tggcgcacca cgagatagga ggcgcagacg gtgagccggc
    12541 ccgggaccgt gctcacgtcc acaagacgct ggaacagccg ctggggaagg cgggtgagtg
    12601 ccgatcgcag caccgtcttg tgtgcggccg acttcagggt cggggtgcgc tctcgtgtac
    12661 gtgccagtcg ctggtccatc gtcatgggtc cgccgggcag gtcgatccgc gtcaggaaca
    12721 gccggttacc gggtgccgct acttcgtcgg gcgtgcgcag gttgacgggc accatcaccg
    12781 gcagggctgc gcaggcggca cggggccatg cgtccgtggc ccattgggtg atcgcgtggg
    12841 ccagagcagt gaggtagacg tcgttggtgc tggctgcgcc ggcgcgtgct gcggtgcgca
    12901 gactgtcgga gggcgcctgg gcccacagca ggtggcggcg gctggacagc ggatgcgcgg
    12961 cggactgcca caggcggtgc tggcgtgcgt gccgcagcag gctcaccgtg ctgcgcgcga
    13021 cctggtgcgg gctgggccgg gcggtggagg aaacgtcgtg tgcgagcgcg gagaactctt
    13081 gcggccgcgg cccgaacagg gtttccagga acctgatcac gttggcgccg tcctggacgg
    13141 cgtggtgggt gagatacagc agcgcgaacc cgtcgcgcac gtggccgtgc agcaagatca
    13201 tgtgccaagc cggggcaccc tctggccacg gttctcgcag ccgtaggcgc accgcatcct
    13261 cgagagccga cgggccttcg ccgatgtgct gggcgagaac gtgccggtcc atgtccgggt
    13321 cggcatgcgt ccaccgtgca gagggcccgc cgccggtcag aaggtgtgtc aggcaaggca
    13381 gggtgtcaag gtggccggtg acgtgctcgc gcagcccggc cagttcgggc acggtgccgc
    13441 tcaggtgcag cactaccccg atcgtcgcgt tggcgtccgg gtgctgcgcc agctgttcag
    13501 ccttgagcac ggcaaggtcg gcgggactgg ggtccggaaa ccggctcatc ttcctcatcc
    13561 caggaacgtg tagagggggg tgctgacggc cgcgccgatc agcatcccga cagcgacctg
    13621 gccgacggtg tggcagtgca gccggacgcg ggaccagccg atcagcacca ccaagggagc
    13681 cagcacgagc atccaggggc cgaagcccgt cacgagaatg gcgagagcgc cagaggcaac
    13741 agcagagtgc accgacactt tccagaagaa cgtaatcatc agcagggcga gcaggacagc
    13801 gaccatcgcc gttacgagcg ccaccaccgc cgcgggagca tccagtgcgt acagcagtgc
    13861 gctgccggtg aggaccgagc ccatcacccc gggggcggcc acgatgcggt cctgcctgcg
    13921 ccgcacgtgc cggtcgcccc agtaccggcg gcgctcaccg aagcgaagga ttagcgtggg
    13981 cagcaccgcg gtgaacaacg cggcgaacaa tccccagccc aggccggccc agccgtcggc
    14041 gtgccagccc aacagcgggg ccaggatgag catccagttc cggggctcgc cgccgtcact
    14101 gagcagccac gcccagcacg cttcacctcg cggcaccagc tcatccgcgg ccgcctgggc
    14161 agggccgaca ccaggagggg ctgatacgtc cggtggagcg gccgaagcct ggttgcattg
    14221 cgacactcgc tacgtcccgc ccctccgtaa ggtgttgccg ccgtgttcgg cgtccatcat
    14281 ccaaacgacg tgctcaccag gcccgtcacg gcaccagcgc gccctgctcg acactcgccg
    14341 tttcttttcg ggtcgccgcg cgtgactggc ggctgcgcgt ccgggcggtg aaggcggcca
    14401 ggcccagggc agccatgccc accgcccagc ctccgcccag tagcaggccg gtgaccggca
    14461 ccacctgcag accggccgcg gtcaccgagg tctgaaccgc tgcgtaggcc gggaggaagc
    14521 gcaccacgag gctgtccgcg tccgggttga tcagcgggtt ctgcagcacc agatcgatgg
    14581 aactgatcat gatggcgagg aacatgccgg ccagctcgct gcgcaccacg gccgccagca
    14641 cgatcccgat accgccgtag accaaggcgc cggtgaacat gcccgcagcg agcaccaagg
    14701 gctgctcggg ccgccagaac aggtgcatcc acgcggtggt gtaggcggcg acgagggccg
    14761 cgaccagcag gagcgcggtg cacttggcga tcgccagaca cgagcgtgga tagccggcgc
    14821 gcgccagacg ctggtcgaag agcgcggagc gggctgtggc gacgaacatc atgaaagcga
    14881 tgaccagcga aagggcctgc agcgcaccgt tgatctggag caggatgttg ccgtccatga
    14941 ccaccgtgcg gccgatcgac cggatgcgga accgcaaggg agtggagggc accacagtga
    15001 aggccagcgt ggtccacagc ggcacgaaca ggaccacgat gagcaacgcc agccggttac
    15061 gggcctgctc gatcagcgca aaacgcaagg ccgtgcggaa gcaggaccac caccgcgtca
    15121 taccgctgcc ctccccgctt cggtctgctc cgtctgcagc aatacgcctg cctgaaggcg
    15181 gtacaggatg tccaggcgcg aggcgtcgta ggcgagatgg gagaccacga gcaccgcgca
    15241 gccccggtcc cgcaaggccg cggccaggtc ccagaaccgc agataggtct cccagtcgaa
    15301 gccctggtac ggctcgtcca gaaggagcac ctgagggtcg tgcatcaagg ccaggaccag
    15361 gttgagtttc tggcgtgtgc cgccgctgag tgcggccacc ggctcgtgcc ggtagtcgct
    15421 gaagttcagc tcctccagca gctcgtaggc ccgagtcaga tggctgatgc cataggcggc
    15481 ctggaagaac tgcaggtgct gttcgacggt gaacgcctgg tggagcacgg tcccctgcgg
    15541 gcagcagccc agccggcctg cccgctccac ggtgccactg tctgcagcga gatctccggc
    15601 caggatgcgc agcagggtgc tcttcccggc cccgttctcg ccgacgatgc ccaccagctg
    15661 gcccggacag agatccagga acaccccgcg caggacagga cgatcccggt agcccttgcg
    15721 tacatcccgc acgtccagaa ccggaccaac tgcactcacc gctccaccct ccacgcccat
    15781 cgcttccttc agggccagcc tgttgcgacc gagtgcagtc acgacctcct cggctgcacc
    15841 gcccccagca acgggcggga accggcggtg ccccgcaagg acagctcagt cgtgtaacga
    15901 cgacggccgt tcacaggaca cgaccgatga ggcagtcaga tccgccacgc gcgatcattg
    15961 acgaacccga attaccaaga gcctcactta cacatacacg tacggttcgt tcgtcgaccc
    16021 gtcccggaat ctgcgaactc ccgcgcttcc gtccacgccg cctgttcccg gcgagctggg
    16081 accagcgctg ggcggttgcg gggctgatgc cgaagaggtc ggcgaccacg atgggcggca
    16141 gatcggtgat ggcctccatc agcgcagtgt tgcgcgcggc acgtacgggg agcccgtgct
    16201 gcctcatctg gtctgccaga cctgccggat tgcgggggcg gccgggcacg acgccgggca
    16261 ggaggagtcg ctggcctgac ggggtcaggg cttctccggg gttggtgatc tgctcgtcaa
    16321 gcaggcgtgc cggcgccggc gggagcagca ccgggtgggc ctcggcgtct tggtggaact
    16381 ggtccgtggt gagttcgacg atgcgcgtca gcggcagggc gtagaggcga accagagcgc
    16441 cgatgatcct tacgtgcagg gggagttcgg tatcggtcag acagcgtcgc agttcggcct
    16501 ggtgggtggt ctcgtcctgg aaggtgccgg gggcctgggt cggccggtgg tggatctcca
    16561 ggtcgcggac gatgtggcgg gcatgtgccc agcggacgaa cgggatgagg cacgtgcgct
    16621 gggtcgcatg tgtgcttgtc cagtcgtcca ggtgcgcctg tgagaggtct cggacgtgca
    16681 ggtcctggtc atccagccag gcgaggaacc tgatggtgac gcggatgccg gtgcagtctc
    16741 ccttgaaggc agccaggctg tagcggcccc gggcggcccg gcgccgggca tccttgacga
    16801 tgccccattc tgcgaagggc cggatgagtg tgacgtggtg agccggaagc cgggcgagtt
    16861 tgcccgtcag ccaaatctcc agccgagcga ggttctcctg tcgctggggc aggacaccag
    16921 cggtcaccag tagcccgcgg acgtaggcgg tgttcgcatc tggcgggagc gcgtccagtg
    16981 cctggtgcgt gagggggtcc gcggcctggg ccaggcgtgc cagcagccgt gcggcggggc
    17041 tgcggcggat ccactccagg accgggtagg ggttggtgac gtcggtgagg acggcttcca
    17101 gggctgccag accggcgggg acctcgccgg cggtgttggt gagaaggtcg tgcaccttgt
    17161 gccgtaggga gcattccggg caccgcccgt ccggccgcag gtccgcgctg gcatggcacg
    17221 tcccgacggc tccaccgtgg gtgcagcacg tggcgcacag gcccgactcg ccgtcgtgtg
    17281 tgacgcagac caggatccgg gtggtctcgc atccggcgca gggcgagggg ttgacgcgcc
    17341 gtcggcggta gcagccactg cacaccgggc ccagcggcca gaagggttgc gccagcgggc
    17401 cgcgccctcg atgtagatct cccggcgccg gatcgcatcg cgcagcgcga ccaggacgca
    17461 cagctcgtac gggatgcgct cgaccctgcc cttgtcgtcg acaacggcct cgcaccagtc
    17521 cttgcgtacg acgccgtcca tcggcaccac gtccgcggcg tcgtagaggc gagtcttgcc
    17581 gtcgacgtcg gcgtacttct ccagcagcgc gagcgcgtcc atcacaggcc gtaggcggtg
    17641 ttgttgcagc ggaatcccag cgtccgcagc agcggcggca gcatctgccg gtagtaggag
    17701 ctgtaggagg agcgcagcgt ggtgcggacc ttggctttga agaccttctc gttcgccttc
    17761 gcctcggcca ctaggccgcg cagcgtctgc tccccgacca ccgggtagag ggctgtgcct
    17821 tccagcgctc cggccatgaa gtcgacctga ccctgtccgg gccggtcaac gccgacaacg
    17881 tcgacccctg gcgcaccatc agcgactcct tcccctggcg cggtcggacc gaaccgctga
    17941 caagcacagc atcccgacta cctcaccgtg atgccctacg cgtcgttgac cagcagcttc
    18001 atgggatgtc ggccacgatc cacgaccgag tgagaccgcc ggtgttccag ggtgaaggca
    18061 cccgcgaatg gtgatgaccg ggcgccccca cgctgtcggc attccgagtc cggtccgcga
    18121 gcctgcgtac tgtcggctgc cctggcgtgc cctcatgtac aggaggagca acctcgtgcc
    18181 tccacagtcg gagggtacgg tcgagcggca ggtcggcgag ttcaccctgg gcgctccgct
    18241 cgccaccgcg ccctgcatgg cctggccgcc atctgcgcct ttggcttccc aggacgcggc
    18301 ttcgtgcgtg cgcgatgcgt gagcggatgg tgcggcacga ggcgtcacga gcgggatgag
    18361 gtacgacccc gcagggtcct gatcaggcgg aacaacaccc tgcggcagcg ttgagcacca
    18421 cccggcaagg attcgatccc actcctaaag cggatgtcgc aagttcacat cctgccgggt
    18481 gcacacaggc caggggcccc gcagagatcc ggggtccttg gcgtttccgg ggtgggggac
    18541 cgtctacttt cgctcgtcgc gttcggcggc gacgaagagc aggcccttcg ggctggagac
    18601 ggcgttgccg aaggcggtga ccgtgccggt cttcaggctg agggtgccga gaccgccctt
    18661 cgcggagacg aacgcctcgc ccctggtgaa gtggccggtg acggcgatga cctcgctctt
    18721 ggcgctgtcc accacgtaga gggtgccctc ggtggaggtc gcgaaggcgg tgtcgtccac
    18781 ctgctggctc agcggcagaa cgtgggcgcg ctgcttcttc gtcccccagt tcttgacgaa
    18841 gaccgcctgc tggtcgccct ggccgtcgag cagcaggctg ccgccgaggc tgggcacgct
    18901 gcgcgggacg aaggtgctgg agtccgggtc ggtcaggttg agcgcgcccg tcttgcccgt
    18961 caccaggttg gtggcggtga tgttgtcgtc gaagaccggg gtggtcttgg cggtggtgcc
    19021 gtggaaggtg accttgtaga gcgcggggcg gccggcggtg ctgcccttgg cgtccgcggt
    19081 cgggttggag gcgacgatgt agacgacgcc gtggcggaca ctgacgttgt cggtgccgcc
    19141 gccgtgcggc agcgagctga agtggtagtg cctgacggcg tggtgcttgc tgtccgggtc
    19201 gacggtgtag gcgctgctgt tgccgtcctc gttgaccgtg gcgacgatct gcccggtgcg
    19261 cttgtcggcg ccgagaccgt cgaccttgcc ggccacgtcc cagtgcgcca cctccttgcc
    19321 gtgcctgtcg aactccacca cggtgctgct cttggtgccg ttggctgcgg gctcgccctt
    19381 ggagccgacg ccgttctggt aaccgacgaa gagcttgtcg ccgagccggg cgatgtcgtc
    19441 cgctccggtc agcttccccc cggcatgggc gaacacggtc gtggagaagc ccgcgggcac
    19501 ggtcgccggc ggcgtcgcgg cactcgccga cgccgagtag ccgatcccgc tgacggccac
    19561 agccgcgacg gttcccgcgt agatgcggac gaacttggtg gacagctttg ccatgacgtt
    19621 cctttaagcc gtgggggtgg ggggctcgtg tccgaccctc cgcagaagtc atggcgcact
    19681 tgtggccctg aacaagccca caggcaacac gtggattaac gtctacatga atgtagacgt
    19741 taatccacgt gtccttacgg tccccgatcg tggagcagcc gagcccggga ggctcgactg
    19801 gtcggaccgg ttccgccgca tgccaggctc accgtcccgt cgtctggccc agtagctatg
    19861 tgatgctctt ggagctacgg atcagaaggt tgcaccaggt agatggcggg cgggaacgaa
    19921 ggagccccag ccgggatgta cccaccggct ggggcttctt cgtgctcggt gttacagggg
    19981 gcggatgttc tccgcctgcg ggcccttctg gccctgcgta acgtcgaact cgacgtgctg
    20041 gccttcccgg agctcgcgga agccctcggt ggcgatgttc gagtagtggg cgaagacgtc
    20101 tgggccgccg ccttcctgct cgatgaagcc gaagcccttt tccgcgttga accacttcac
    20161 agtgcccttg gccatgtgct gtctccttcg aggggctcgt atcgggtccc acgccgtgcg
    20221 ggatccggag gtgatcgccc tggtccggag aggcgttgaa cagccagaac gcccgcgatt
    20281 gcgatcacgg gcgaacggga cttcggaacc acgactgctg tttacgacgc tacaccggct
    20341 ggtagcactc ggcgatagag aaacaccggc ccgacaccga ccgggagtcc caggcgctcg
    20401 gaatcgtggg gcgactggcc gccaccgaca gccgactccc gagtgcggct cacctgccgt
    20461 tgggtgaggc tgcggttatg gctgagcgtc gagtgatcgt gttcccgccc ggcgagggtg
    20521 gcggccgtcg tgtccaggtc gacagcgaga ctctgggcac cgcacacagc ctgcacgacc
    20581 tgagcgtgtt tcttgagcgt gccggcctgg aggggttgga cgtggtggac ctggtgaact
    20641 cgccgctgat cgagtggctc ggcggcggcc cggaggtttg ggagcactga acgccccgcc
    20701 ggaggctggt cgccgccgtc gcccgttcgg cgcgcagcgg tcgctgtcgc acccgggttc
    20761 gcgttcgctg ggagcgagcc ccgcatctga ccggagctca ccccccatca agccaaggag
    20821 acacagccat ggaccaaggc aagatccatg agtgggacgc ggacccgggc gagggaagca
    20881 tcaagagcga ccgaggtggt cccgtgctgt acttcacggt agacgacctc atgatcgacc
    20941 ccggcgagat ccatcagggg gacaccgtct cgttccgggt cgaaggaccc ggaaaagcag
    21001 ccatggtcaa caaggcctga gccctgaaag cagcgtgcgg caggcaccac cccgaaggtg
    21061 aacgggtggt gcctgggggg ggtctggatc acacagatcg gccgctgtct cgaccaggcg
    21121 ggagacctca gcagccacag cgctcattgc ccgcgaagag gccgtgccag tcgcgtgcca
    21181 gatcgtacgt tcttggcgcc tgccgcgctt attgcaagct aaggagggca aggtcaggac
    21241 tgcgcggtcc ggaacgcgag ataccggctg aaggcttcgt ggctgtcggg ggtgaagcac
    21301 cactcaagca gggccgaccg cagttccggc tccgtcagcc aggcatgcca ggcgacctca
    21361 tcgggatcgg ggaccacggc atccggcacc acggcttcgt gcacgccgag ccagtgaggg
    21421 ctcaaaccgc ttcggttgat gaacgtgaac aacaagcgcg gcagcacacg agtccccagc
    21481 tcttcagcca gttcccgcgc agcggccttt tcataggact caccgatatc cacggcgcca
    21541 ccgaccacga cctcgtagaa cccggggaag cgcgacagct gctccgaccg ccggtggacg
    21601 aggatccgcc cacgctcatc acgacacacc gtcacggcga cccggtgcag ccaaccctcc
    21661 cggatggcct gtcggcggct gaccaccacc cccagcacac gatcttgatc gtcgacacgc
    21721 tccactagtt catccacgac gcacaccctg gcagagccca ccgacaacgc cgcttgccgg
    21781 cggctcctgg agggtgtccc gagagcgcct gcaccaggag gtcggacgcg gatgacgaca
    21841 gttgtcgtgc aaatacgaca cctatcgtac tcaggctcag cggtgcgcac gtcgagcagg
    21901 tgggcaacca gaacaccggc gattgcaagg gtctgtccag ccaacggtgt aactcgggtg
    21961 atgtgagtta tcggcggccg acggagagtc ggccgtcgaa ggcgatgtcg aatgcctgca
    22021 gggcgggctt ccaacgcatg gtccagcgtt tgcgtccctg gccggtgggg tcgaggctca
    22081 tgatggccat gtagacgcat ttgagggctg cggcctcgtt cgggaagtgc ccgcgggccc
    22141 ggacggcttt tcgtatgcga gcgttgaccg actcgatagc gttggtggtg cagacgacac
    22201 ggcggatctc ggtgtcgaac tg
//
