LOCUS       NZ_CP047020            21086 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Streptomyces broussonetiae strain T44 chromosome.
ACCESSION   NZ_CP047020
VERSION     NZ_CP047020.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces broussonetiae
  ORGANISM  Streptomyces broussonetiae
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9735779)
  AUTHORS   Mo,P.
  TITLE     Streptomyces sp. strain T44 isolated from rhizosphere soil of
            Broussonetia papyrifera
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9735779)
  AUTHORS   Mo,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2019) College of Life Science and Technology,
            Central South University of Forestry and Technology, No. 498,
            Shaoshan South Road, Changsha, Hunan 410004, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 25-OCT-2019
            Assembly Method                   :: HGAP v. 3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 12.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009796285.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 17:56:09
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,022
            CDSs (total)                      :: 8,931
            Genes (coding)                    :: 8,515
            CDSs (with protein)               :: 8,515
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 416
            CDSs (without protein)            :: 416
            Pseudo Genes (ambiguous residues) :: 0 of 416
            Pseudo Genes (frameshifted)       :: 171 of 416
            Pseudo Genes (incomplete)         :: 334 of 416
            Pseudo Genes (internal stop)      :: 29 of 416
            Pseudo Genes (multiple problems)  :: 110 of 416
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:31:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6192700
            Orig. end                         :: 6213786
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP047020.1.
            Bacteria and source DNA available from Zhao YL.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21086
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="18"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21086
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21086
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11086](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11086
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(291..1607)
                     /gene="aroA"
                     /locus_tag="GQF42_RS28645"
                     /old_locus_tag="GQF42_28645"
     CDS             complement(291..1607)
                     /EC_number="2.5.1.19"
                     /GO_function="GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="aroA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674885.1"
                     /locus_tag="GQF42_RS28645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_28645"
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="WP_158924566.1"
                     /transl_table=11
                     /translation="MAPNTALPALWPAPHASGAVDATVHVPGSKSVTNRALVLAALASE
                     PGWLRRPLRSRDTLLMAGALRAMGVEIEEGVGPDGTGEAWRVLPTGLHGPATVDVGNAG
                     TVMRFLPPVAALADGPIRFDGDPRSYERPLSGVIDALRVLGARIDDDGRGALPLTVHGG
                     GALDGGPVSVDASSSSQFVSALLLSGPRFNQGVEVRHTGATLPSVPHIRMTVDMLRAVG
                     AQVDTPESGGEPNVWRVTPGALLGRDLTIEPDLSNAQPFLAAALVTGGKVVVPDWPERT
                     TQPGDRLREIFTEMGGSCELTDYGLMFTGSGAIHGIDVDLGDVGELTPGIAAVAALADS
                     PSTLRGVAHLRLHETDRLAALTKEINELGGDVTETADGLHIRPRPLHGGTFHTYEDHRM
                     ATAGAILGLAVEGVLIENVATTAKTLPDFPELWTGMLGQ"
     misc_feature    complement(1609..1625)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.34"
                     /tool="antismash"
     gene            complement(1636..2358)
                     /locus_tag="GQF42_RS28650"
                     /old_locus_tag="GQF42_28650"
     CDS             complement(1636..2358)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674886.1"
                     /locus_tag="GQF42_RS28650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_28650"
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_158924568.1"
                     /transl_table=11
                     /translation="MDSLAATSLPGLWDRLTGTQPDPDLWVVIATLAAALAVVAPHPVW
                     RISRNAVTIAHEGGHGLIALLTGRQLTGIRLHSDTSGLTVSRGKPYGLGMILTAAAGYT
                     APSLLGLGGAALLAAGRITLLLWVATALLVTMLVMIRNAYGVLTVVLAGGAFVLVSWLA
                     GPQVQAAFAYAVVWFLLLGGVRPPFELQAKRTRGGAGDSDADQLSRLTHVPAGLWLFLF
                     HAVSVCSLIGGGRWLLEG"
     gene            2464..3279
                     /locus_tag="GQF42_RS28655"
                     /old_locus_tag="GQF42_28655"
     CDS             2464..3279
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980380.1"
                     /locus_tag="GQF42_RS28655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_28655"
                     /product="SOS response-associated peptidase"
                     /protein_id="WP_158924570.1"
                     /transl_table=11
                     /translation="MCGRYASSRRPEDLAGVFEVEKWDPEETLEPDYNVAPTKEVYAVL
                     DRPLKDADSPRPVRQLRKLKWGLVPSWAKTPEGGARMINARAETVHEKPSYRRAFAARR
                     CILPADGYYEWVTGTQERDLEVEGKKKRPRKQPYFVLPADGSVFAMAGLYEFWRDRTLP
                     DDHPQAWWATCSVITTEAERTPLAVAPAQGPGTLAEIHPRMPLMLTPDRWDAWLDPART
                     DPDALRDLLAPPPPGLLRAYPVSTAVSNVRNNGAELLKELEAPEEGTLF"
     gene            3281..3907
                     /locus_tag="GQF42_RS28660"
                     /old_locus_tag="GQF42_28660"
     CDS             3281..3907
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973757.1"
                     /locus_tag="GQF42_RS28660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_28660"
                     /product="alpha/beta family hydrolase"
                     /protein_id="WP_158924572.1"
                     /transl_table=11
                     /translation="MIEIVETDAGTARITWHKAKRPALVLAVSHGAGGGIEARDLMALA
                     AALPAHGVTVALVEQPWRVAGRKVAPAPRTLDTGWRGIWPALAGMELPVISGGRSAGAR
                     VACRTATELGAHAVLALSFPLHPPGKPEKSRAEELLGTGVPTLVVQGGNDPFGRPAEFP
                     RGSYELIEVPYGDHGFAVPKRAEITQERALEIITDGVVKWAASLG"
     gene            4164..4859
                     /gene="sigR"
                     /locus_tag="GQF42_RS28665"
                     /old_locus_tag="GQF42_28665"
     CDS             4164..4859
                     /codon_start=1
                     /gene="sigR"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973756.1"
                     /locus_tag="GQF42_RS28665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_28665"
                     /product="RNA polymerase sigma factor SigR"
                     /protein_id="WP_199272837.1"
                     /transl_table=11
                     /translation="MGAVTGTDAGTDNGQAEQPEGRGVGAEAASESSTERSARFERDAL
                     EYLDQMYSAALRMTRNPADAEDLVQETYAKAYASFHQFREGTNLKAWLYRILTNTFINS
                     YRKKQREPQRSAAEEIEDWQLARAESHMSTGLRSAESQALDHLPDSDVKEALQAIPEEF
                     RIAVYLADVEGFAYKEIADIMGTPIGTVMSRLHRGRRQLRGMLEDYARDRGLVPAGAGE
                     SDEAKGSGS"
     gene            4856..5158
                     /gene="rsrA"
                     /locus_tag="GQF42_RS28670"
                     /old_locus_tag="GQF42_28670"
     CDS             4856..5158
                     /GO_function="GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016645393.1"
                     /locus_tag="GQF42_RS28670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_28670"
                     /product="mycothiol system anti-sigma-R factor"
                     /protein_id="WP_158924576.1"
                     /transl_table=11
                     /translation="MSCGESHETDCSEVLDHLYEFLDSEMPDVDRDKFQHHFEECSPCL
                     EKYGLEQAVKKLVKRCCGHDDVPADLRAKVMGRIDLIRSGQAVPEHDVTATAQDG"
     gene            5297..6601
                     /locus_tag="GQF42_RS28675"
                     /old_locus_tag="GQF42_28675"
     CDS             5297..6601
                     /EC_number="3.1.4.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674892.1"
                     /locus_tag="GQF42_RS28675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_28675"
                     /product="HD-GYP domain-containing protein"
                     /protein_id="WP_158924578.1"
                     /transl_table=11
                     /translation="MEAVPARARGYVAAVAVLALLCLLPLPTVRTPWWALGLLTALYAA
                     CEYAVRRRFGSTFHPVLLAAAFLLPAPAAALVPLPAALLCPVEHRPALLRRLWRAARPA
                     LAVWGAAKVHWTLGGRDAVVGSDFPYALLPAGAAVLAFCLILTVLDGGILAFAERVPLR
                     RAWRGLLSRSLAPVAVHGLAGLMMAVLWRSPYGPVAALLVLLPMWVSWWIFAQYHRERA
                     AHQATIRALVQAVDIKDGYTRGHSERVGQASVLIARELGMDDDRVEVLRFAGILHDVGK
                     LGVPTRLLRKEGPLTPEERRIIELHPEYGHEMVRGISFLGEARAAILHHHERLDGSGYP
                     YGLAGSGIPECARVVAVADAFDAMTSTRSYRRARPVETAVAELERCAGTQFDPRMVEAL
                     ARALRRQGWHPTVTADEPAHETAPRQRAAGTGTPR"
     gene            6598..7890
                     /locus_tag="GQF42_RS28680"
                     /old_locus_tag="GQF42_28680"
     CDS             6598..7890
                     /EC_number="3.1.4.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674893.1"
                     /locus_tag="GQF42_RS28680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_28680"
                     /product="HD-GYP domain-containing protein"
                     /protein_id="WP_158924580.1"
                     /transl_table=11
                     /translation="MTALRLIHGAAALTAAGSLAATLGTGLTGRGVALAFGVLIAVGEL
                     TRWSDAEAGRAAPLAAAGSLAYALLGDDAGRPTGHHADQVVTVVLVASVLGAVPHIWSG
                     RTPTLDHLARRVLTVGFAAVCFQPLYNQRLFASWNGPAYALLLIALLGLTGLCDAVLAA
                     ALAHCRTHWPFAPLLREELRGLLGIGSAVGATGAVMALAVAVVGLWALPVFCLPLLLTQ
                     LSVRRYAAVRATYRQTIASLARATEIAGCTPTGHARRVAALSLAVGRDLGLAGGELTVL
                     EYAALMHDIGQLSLVDPVPAGATAGLPPAQQRRIALLGGAVVRQTGVDAAVAVVVERQA
                     DPCREQPLAARIVRAVNAYEEKTRDAGPEGPLRALEELRLTAAGDYAPEVVESLARVLA
                     QPRGWCRTAPAQGDGRHTALSDPTLGWVTHG"
     gene            7991..8971
                     /locus_tag="GQF42_RS28685"
                     /old_locus_tag="GQF42_28685"
     CDS             7991..8971
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889310.1"
                     /locus_tag="GQF42_RS28685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_28685"
                     /product="hypothetical protein"
                     /protein_id="WP_158924582.1"
                     /transl_table=11
                     /translation="MRIFGKGRHRPSASWRQATDRAFTLIGDGRYEDAGELLTRAADLE
                     PWLSESWFNLALLHKFRHDWEQARAAGLRAVALLDRETGTPDWWNVGIAATALQDWPLA
                     RRAWQAYGLKVPGGATTAGEPAGMELGSAAVRLSPEGEAEVVWGRRLDPARIEVLSIPL
                     PSSGRRWGEVVLHDGVPHGERTTSAGHAYPVFDEIELWAPSPVPTWVVLLEAATEADRD
                     ALEQLAADAGFAAEDWSSSVRLLCRMCSESRMPSDEGEGVHLDPHDHSEPGHPGPLGHR
                     TDGQLWVPERECGVAAPASLVRGLLDGWIADSPDSRDWRDLEEVC"
     gene            9059..9709
                     /gene="def"
                     /locus_tag="GQF42_RS28690"
                     /old_locus_tag="GQF42_28690"
     CDS             9059..9709
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983603.1"
                     /locus_tag="GQF42_RS28690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_28690"
                     /product="peptide deformylase"
                     /protein_id="WP_158924584.1"
                     /transl_table=11
                     /translation="MAQQDTDQQHAGVLPVDDEGYVVDTEDCEEREKAWRERGASRPIT
                     VVGNPVLHKECRDVTEFGDELQQLVADMFASQRTAEGVGLAANQIGVDLKVFVYDCPDD
                     DGVRHTGVVCNPKLVELAADRRRLDDSNEGCLSVPGAYAPLARPDYAEVTGQDERGNPI
                     KVRGTGYFARCLQHETDHLYGYLYIDRLSKRDRKDALRQMAENEPRYPVIAND"
     gene            10001..11086
                     /gene="cyc1"
                     /locus_tag="GQF42_RS28695"
                     /old_locus_tag="GQF42_28695"
     CDS             10001..11086
                     /EC_number="4.2.3.37"
                     /GO_function="GO:0052680 - epi-isozizaene synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cyc1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007384601.1"
                     /locus_tag="GQF42_RS28695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_28695"
                     /product="epi-isozizaene synthase"
                     /protein_id="WP_158930706.1"
                     /sec_met_domain="T1TS (E-value: 2.9e-64, bitscore: 217.1,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQAFPHSTTATPTAVVVPPSLALPVIESAFPRQLHPYWPQLQEKT
                     RLWLLEKRLMPAGKVQEYADGLCYTDLMAGFYVNAADEVLQAIADYSAWFFVWDDRHDR
                     DIVHGRVGDWRRLRYRLHAALDAPRHHLHHPDPLVAGFADSVLRLYGFLPRTWNQRFSR
                     HFHTVIEAYDREFRNRTEGYVPGVEEYLALRRHTFAHWIWTDLLEVSAGCELPDAVRKN
                     PAFRRAALLTQEFAAWYNDLCSLPKEIAGDEVHNLGICLISHEGLTLEEAVDEVRRRVE
                     ECIRDFIEAEQEALQFADAIADGSIRGKELSTAVRDSVGNMRNWFSSVYWFHHESGRYM
                     VDSWDDQSTPPYVTNEAVGEK"
     gene            11083..12453
                     /locus_tag="GQF42_RS28700"
                     /old_locus_tag="GQF42_28700"
     CDS             11083..12453
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674897.1"
                     /locus_tag="GQF42_RS28700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_28700"
                     /product="cytochrome P450"
                     /protein_id="WP_158924586.1"
                     /sec_met_domain="p450 (E-value: 7.1e-67, bitscore: 225.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLDSVEPVTTEAAELREPPLAGGAVPVLGHGLKLVRDPLAFMSG
                     LRNHGDVVRLKLGPKTVYAVTTPALTGALALSPDFKIDGPLWESLEGLLGKEGVATANG
                     PRHRRQRRTIQPAFRLDAIPGYGPIMEEEAHRLTERWKPGETVDCTSESFRVAVRIAAR
                     CLLRGEYMDERAERLSADLATVFRGMYRRMVVPLGPLYRLPFPANREFNRALADLHLLV
                     DEIVAERRASGQKPDDLLTALLEAKDDNGDPIGEQEIHDQVVAIVTPGSETVASTIMWL
                     LQVLAAHPEHAEKVRTEVESVTGGRPVAFEHVRALTHTNNVVVEAMRLRPAVWILTRRA
                     VTETSLGGYRIPAGADIVYSPYAIQRDARSYDRNLDFDPDRWLPERAKQVPKHAMSPFS
                     TGNRKCPSDHFSMTQLTLITAAISAKYRFEQVTGSNDSTRVGITLRPHDLLLRPMPW"
     gene            complement(12486..13448)
                     /locus_tag="GQF42_RS28705"
                     /old_locus_tag="GQF42_28705"
     CDS             complement(12486..13448)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018544423.1"
                     /locus_tag="GQF42_RS28705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_28705"
                     /product="GlxA family transcriptional regulator"
                     /protein_id="WP_158924588.1"
                     /transl_table=11
                     /translation="MLKNVAAVLLEGVHPFELGVVCEVFGIDRRDEGLPVYDFAVVSAE
                     GPTLGTRCGFTVSTPYGLERLEEADLIAVPAGDSYVERDYPEELLDALRRAVGRGARVL
                     SVCSGVFLLAAAGLLEDRRCAVHWHHAEQLARRYPRIAVEPDVLYVDEDPVITSAGTAA
                     GIDACLHIVRKEQGPEVANKIARRMVVPPHRDGGQAQYIERPLPRGSCDTVGEVLVWME
                     EHLEAEVTVEQLAARAHMSPRTFARRFQQETGTTPYRWILRQRVLRAQALLEGTDETVD
                     AIAWRTGFGTAAALRHQFVRALGTTPNAYRRTFRGPHAA"
     gene            complement(13696..14715)
                     /locus_tag="GQF42_RS28715"
                     /old_locus_tag="GQF42_28715"
     CDS             complement(13696..14715)
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009190555.1"
                     /locus_tag="GQF42_RS28715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_28715"
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_158924591.1"
                     /transl_table=11
                     /translation="MSTTTRNANLLDPGFELTLRPMRYPDFYERYRDAIKNTWTVEEVD
                     LHSDVADLAKLTPEEQHLIGRLVAFFATGDSIVANNLVLTLYKHINSPEARLYLSRQLF
                     EEAVHVQFYLTLLDTYLPDPEDRAAAFAAVENIPSIREKAEFCFKWIDSVDKIDRLETK
                     ADRRRFLLNLICFAACIEGLFFYGAFAYVYWFRSRGLLHGLATGTNWVFRDETMHMSFA
                     FDVVDTVRKEEPDLFDDELQQEVVDMLKEAVEAELQFARDLCGDGLPGMNTESMRQYLE
                     CVADQRLTRLGFAPVYGSENPFSFMELQGVQELTNFFERRPSAYQVAVEGTVDLDEDF"
     gene            complement(14715..17084)
                     /locus_tag="GQF42_RS28720"
                     /old_locus_tag="GQF42_28720"
     CDS             complement(14715..17084)
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674902.1"
                     /locus_tag="GQF42_RS28720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_28720"
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="WP_158924593.1"
                     /transl_table=11
                     /translation="MTIAPADPASASGLDTDGPGTALLRTLTELTADLPDADPGRVAAA
                     ALRGRSARADEAELRELATEAAAGLISEDPAYSRLAARLLTLSIRAEAGSQGVTSFTES
                     VAVGHREGLIADRTAEFARLHAARLDALIDTGADDRFGYFGLRTLHSRYLLRHPITRKV
                     IETPQHFMLRVAAGLAEDDTARSVDEVAALYRLMSRLDYLPSSPTLFNSGTRHPQMSSC
                     YLLDSPLDELDSIYDRYHQVARLSKHAGGIGLSYSRIRSRGSLIRGTNGHSNGIVPFLK
                     TLDASVAAVNQGGRRKGAAAVYLETWHSDIEEFLELRDNTGEDARRTHNLNLAHWIPDE
                     FMRRVNADAEWSLFSPADVPELVDLWGEEFDAAYRKAEQAGLAKKTIPARELYGRMMRT
                     LAQTGNGWMTFKDAANRTANQTALPGHVVHSSNLCTEILEVTDDGETAVCNLGSVNLGA
                     FVDAARGDIDWERLDETVRTAVTFLDRVVDINFYPTEQAGRSNARWRPVGLGAMGLQDV
                     FFKLRLPFDSAEARALSTRIAERIMLAAYEASTDLAERSGPLPAWEKTRTAQGVLHPDH
                     YDTELTWPERWDALRRRVASVGMRNSLLLAIAPTATIASIAGVYECIEPQVSNLFKRET
                     LSGEFLQVNSYLVQDLKNLGVWDARTREALRDSNGSVQGFVWIPEEVRALYRTAWEIPQ
                     RGLIDMAAARTPFLDQAQSLNLFLETPTIGKLSSMYAYAWKSGLKTTYYLRSRPATRIA
                     RAAQAQSTAGIPVQQAADPDAVACSLENPESCEACQ"
     regulatory      complement(17210..17381)
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(17332..17346)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 23.4"
                     /tool="antismash"
     misc_feature    complement(17363..17377)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 21.66"
                     /tool="antismash"
     gene            complement(17500..19116)
                     /gene="mctP"
                     /locus_tag="GQF42_RS28725"
                     /old_locus_tag="GQF42_28725"
     CDS             complement(17500..19116)
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006848 - pyruvate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="mctP"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674905.1"
                     /locus_tag="GQF42_RS28725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_28725"
                     /product="monocarboxylate uptake permease MctP"
                     /protein_id="WP_158924595.1"
                     /transl_table=11
                     /translation="MKNGVNGVALGVFIFFFLAVTVMGFLAARWRKAENEHSLDEWGLG
                     GRSFGTWITWFLLGGDLYTAYTFVAVPAAVYAAGASGFFAVPYTILVYPLIFTFLPRLW
                     SVSHRHGYVTTSDFVRGRFGSKGLSLAVALTGILATMPYIALQLVGIQAVLDVMGVGGG
                     DNTNWFMKDLPLLIAFGVLAAYTYSSGLRAPALIAFVKDALIYIVIAVAIIYIPIKLGG
                     FDDIFAKAGHAFSQVSPATGKPRGALAPPEAGQWTYATLALGSALALFMYPHSITATLS
                     SKSREVIRRNTTILPLYSLMLGLLALLGFMAIAAGVKVTNGQLAIPQLFEDMFPDWFAG
                     VAFAAIGIGALVPAAIMSIAAANLFTRNIYKDFIKPDATPRQEAQVSKIVSLLVKFGAL
                     LFVLTMDKTVAINFQLLGGIWILQTFPALVGGLFTRWFHRWALLTGWAVGMIYGTVAAY
                     GVASPTQKHFGGSSKEIPGIGEIGYIGFTAFVLNVAVTVVLTLVLRAVKAPEGIDETRP
                     EDYTADAGDQGVETELVGVAH"
     gene            complement(19113..19376)
                     /locus_tag="GQF42_RS28730"
                     /old_locus_tag="GQF42_28730"
     CDS             complement(19113..19376)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010984454.1"
                     /locus_tag="GQF42_RS28730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_28730"
                     /product="DUF3311 domain-containing protein"
                     /protein_id="WP_158924597.1"
                     /transl_table=11
                     /translation="MSDTPEVRPPVVTPVRVIIGLCLVAPFVAMLWVGSYAKTDPAFIG
                     IPFFYWYQMLWVPISAALTMTAYKLWQYDQRSPTAPQGGEAK"
     misc_feature    complement(19463..19477)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.75"
                     /tool="antismash"
     misc_feature    complement(19598..19611)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.88"
                     /tool="antismash"
     gene            complement(19821..20585)
                     /locus_tag="GQF42_RS28735"
                     /old_locus_tag="GQF42_28735"
     CDS             complement(19821..20585)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973740.1"
                     /locus_tag="GQF42_RS28735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_28735"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_158924599.1"
                     /transl_table=11
                     /translation="MSTDVSSAENEAGTTVRTARVPKYYRLKKHLLDMTETQAPGTPVP
                     PERTLAAEFDTSRTTVRQALQELVVEGRLERIQGKGTFVAKPKVSQALQLTSYTEDMRA
                     QGLEPTSQLLDIGYITADERLADLLGISAGGRVLRIERLRMANGEPMAIETTHLSAKRF
                     PALRRSLVKYTSLYTALAEVYDIHLAEAEETIETSLATPREAGLLGTDVGLPMLMLSRH
                     SLDHEGRPVEWVRSVYRGDRYKFVARLKRPAE"
     misc_feature    20720..20735
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.49"
                     /tool="antismash"
ORIGIN
        1 cacgatccgg gccagggtgt ccttcctgcc ggacaggtcg ccgaccagcg ccacccggtc
       61 gcccaccacg gcggccttgc ggcccagttc gcgggccttc atcgccatga ccgtgcggtc
      121 gccgaccaga caggtcagcc ggccccggtc gacggtgagg accattcctt cggccgcgtc
      181 ctcgtgcttg ggccggatgt tcgtccgcgg ccggttgccc ttgcggttgg gacgggtacg
      241 gatgtcgtcc tcgtcggtgt gcttgccgta gcggcgcatg gcgtacgtcc ctactgcccg
      301 agcatcccgg tccacagctc ggggaagtcc ggcagggtct tggccgtcgt cgccacgttc
      361 tcgatgagca cgccctcgac cgccaggccg aggatcgcgc cggcggtcgc catgcggtgg
      421 tcctcgtagg tgtggaaggt cccgccgtgc agcgggcgcg ggcggatgtg cagaccgtcg
      481 gccgtctccg tgacgtcacc gcccagttcg ttgatctcct tggtgagcgc ggccagccgg
      541 tccgtctcgt gcagtcgcag atgggccacg ccgcgcagcg tggaggggga gtccgcgagg
      601 gccgccacgg ccgcgatgcc gggggtcagc tcgccgacgt cgccgaggtc cacgtcgatc
      661 ccgtggatgg cacccgaacc ggtgaacatc agcccgtagt cggtgagttc gcaggaaccc
      721 cccatctcgg tgaagatctc ccgcagccgg tcaccgggct gcgtggtccg ctccggccag
      781 tcggggacga ccaccttgcc gccggtcacc agcgccgccg ccaggaacgg ctgggcgttg
      841 gacaggtccg gctcgatcgt caggtcccgg ccgagcagcg cacccggcgt cacccgccac
      901 acgttcggct cgccgccgga ctccggggtg tccacctggg cgccgaccgc gcgcagcatg
      961 tccacggtca tccggatgtg cggcacggag ggcagggtcg cgccggtgtg gcggacctcg
     1021 acgccctggt tgaagcgcgg gccggagagc aggagagccg acacgaactg ggaggacgag
     1081 gaggcgtcga ccgacaccgg gccgccgtcc agtgccccgc cgccgtgcac ggtcagcggc
     1141 agcgcgcccc ggccgtcgtc atcgatccgg gcgccgagca cgcgcagcgc gtcgatcaca
     1201 ccgctgagcg ggcgctcgta ggaccgcggg tcgccgtcga accggatcgg accgtcggcc
     1261 agtgcggcga ccggcggcag gaagcgcatc accgtgccgg cgttgccgac gtcgaccgtg
     1321 gccgggccgt gcaggccggt cggcagcacc cgccaggcct cacccgtgcc gtcggggccg
     1381 accccttcct cgatctccac gcccatggcc cgcagcgcgc ccgccatcag cagggtgtcg
     1441 cgggagcgca gcgggcggcg cagccagccc ggctcggagg cgagggcggc gaggacgagg
     1501 gcgcggttgg tgaccgactt ggaccccggc acgtggaccg tcgcgtcgac ggctccgctc
     1561 gcgtgcgggg cgggccagag tgcgggaagg gcggtgttcg gggccatggg cccactttat
     1621 aaggagggtc ggccgtcaac cttccagcag ccagcgcccc ccgccgatga gcgagcacac
     1681 cgacaccgcg tggaacagga acagccacag tcccgcgggg acgtgcgtca gccgggacag
     1741 ctggtccgcg tccgagtcgc ccgccccgcc ccgggtgcgc ttcgcctgca gttcgaaggg
     1801 cggccggacc ccgccgagca gcaggaacca caccaccgcg taggcgaacg ccgcctgcac
     1861 ctggggcccc gccagccagg acaccagcac gaaggcgccc ccggccagga cgacggtcag
     1921 gacgccgtac gcgttgcgga tcatcaccag catcgtcacc agcagggccg tcgcgaccca
     1981 gagcaggagg gtgatccggc cggcggccag cagggcggct cctcccagtc ccagcaggga
     2041 aggcgcggtg taccccgccg ccgccgtgag gatcatgccc agcccgtacg gcttgccccg
     2101 gctgaccgtg aggccgctgg tgtcggagtg cagccggatg ccggtgagct gccggccggt
     2161 gagcagggcg atcagaccgt ggccgccctc gtgcgcgatg gtgaccgcgt tgcgcgatat
     2221 gcgccacacc gggtgcgggg cgacgacggc cagcgcggcg gcgagcgtcg cgatcaccac
     2281 ccacaggtcg gggtcgggct gggtgccggt gagccggtcc cagaggccgg gcagcgaggt
     2341 ggcggcgagg ctgtccattc cggtggtggc tccctgtcgt cgtgatcgga gaggagtcgg
     2401 cgcgaagcgc cgtcgtcgtg gggtggtggt cgggtgacgg gtgggcctgg cagtgtggca
     2461 cgtatgtgcg gacggtatgc atcgagtcgt aggcccgagg atctcgcagg agtcttcgag
     2521 gtcgagaagt gggatcccga ggagactctg gagcccgact acaacgtggc gccgaccaaa
     2581 gaggtctacg ccgtcctcga ccgtcccctg aaagacgcgg actccccgcg tccggttcgc
     2641 cagctgcgca agctcaagtg gggactggtg ccgtcctggg ccaagacgcc cgagggtggc
     2701 gcccggatga tcaacgcgcg cgcggagacc gtgcacgaga agccgtccta ccggcgcgcc
     2761 ttcgccgccc ggcgctgcat cctgcccgcc gacggctact acgagtgggt caccgggacg
     2821 caggaacggg atctggaggt cgagggcaag aagaagcggc cccgcaaaca gccgtacttc
     2881 gtgctgcccg ccgacggctc ggtgttcgcg atggccgggc tgtacgagtt ctggcgcgac
     2941 cgcaccctgc ccgacgacca cccgcaggcc tggtgggcca cctgctcggt gatcaccacg
     3001 gaggccgagc ggaccccgct ggccgtggcc cccgcccagg gcccgggcac gctcgccgag
     3061 atccaccccc ggatgccgct gatgctcacc ccggaccgct gggacgcctg gctcgacccg
     3121 gcccgcaccg accccgacgc cctgcgcgac ctgctcgccc cgcccccgcc cggtctgctg
     3181 cgcgcctacc cggtctccac ggccgtcagc aacgtccgca acaacggcgc ggagctgctg
     3241 aaggagcttg aggcgccgga agagggcaca ctcttctagc gtgatcgaga ttgtcgagac
     3301 cgacgccggg accgcacgca tcacctggca caaggcgaag aggcccgcac tcgtccttgc
     3361 cgtgagccat ggcgcgggag gcggcatcga ggcccgcgac ctgatggcgc tcgcggcagc
     3421 cctgcccgcg cacggcgtca ccgtcgccct ggtcgagcag ccctggcggg tcgcgggccg
     3481 gaaggtcgcg cccgccccca ggacgctgga caccggatgg cgcgggatct ggcccgcgct
     3541 ggccgggatg gagctgccgg tgatctccgg cggccgcagc gccggtgccc gggtcgcctg
     3601 ccgtaccgcc accgagctgg gcgcgcacgc cgtgctcgcg ctgagcttcc cgctgcaccc
     3661 gccgggcaag ccggagaagt cccgcgccga ggagctgctc gggaccgggg tgcccacact
     3721 cgtcgtccag ggcggcaacg accccttcgg ccggccggcc gagttcccca ggggctcgta
     3781 cgaactgatc gaggtgccgt acggcgatca cgggttcgcg gtgcccaagc gcgcggagat
     3841 cacccaggag cgggccctgg agatcatcac cgacggtgtc gtgaagtggg ccgcgtcact
     3901 cgggtgacgg ccgggaatgt tgcgtgacac accactgttg tggcggacag aagtgctgag
     3961 gcctcggcac cgacgtcgta gggaaggaag tccgccgcat gggttcgacc atctgcccgg
     4021 cccgcagcag cagtactgac ctggactgga cggtgctgca ggcggccaag acggcaccta
     4081 ttcgagcggc ggcaggcacc ggtcgtgttc tatcctccga atcgagtggg accggtctcg
     4141 gtcctgcccg ggatcttgag gaggtgggtg cggtcaccgg taccgacgca gggaccgaca
     4201 acggccaggc ggagcagccc gagggccggg gcgtgggcgc ggaggcggcc tccgagtcca
     4261 gcacggagcg cagtgcgcgc ttcgagcggg acgcgctcga atacctcgac cagatgtact
     4321 cggccgcgct gcgcatgacg cgcaacccgg ccgacgccga ggacctggtg caggagacgt
     4381 atgccaaggc gtacgcgtcc ttccaccagt tccgtgaggg caccaacctc aaggcgtggc
     4441 tgtaccggat cctcaccaac acgttcatca actcctaccg caagaagcag cgcgagccgc
     4501 agcgctccgc cgcggaggag atcgaggact ggcagctcgc ccgcgccgag tcgcacatgt
     4561 cgacgggtct gcgctccgcc gagtcgcagg cgctcgacca cctgcccgac tcggatgtga
     4621 aggaagcgct gcaggcgatc cccgaggagt tccgcatcgc cgtctatctc gcggacgtag
     4681 agggctttgc gtacaaggag atcgcggaca tcatggggac acccatcggt acggtgatgt
     4741 cccggctgca ccggggccgc cgtcaactgc gcggcatgct ggaggactat gcccgtgacc
     4801 gcgggctggt accggcgggc gccggggagt cggacgaagc gaaaggctcg ggctcatgag
     4861 ctgcggagag tcgcacgaga cggactgcag tgaggtcctc gaccatctgt acgagttcct
     4921 cgacagcgag atgccggacg tcgatcgcga caagttccag caccacttcg aggagtgctc
     4981 tccgtgcctg gagaagtacg gcctggagca ggccgtgaag aagctggtca agcggtgctg
     5041 cgggcacgac gacgtgcccg cggacctgcg cgccaaggtc atggggcgga tcgacctgat
     5101 ccgctccggg caggccgtgc cggaacacga cgtcaccgcc acggcccagg acggctgagc
     5161 gcccgctccc ggagcgcgga ccgccccggt catcacccga acgtgctaat cctcaggtca
     5221 taagccccct gccccgccgt tcccgcccta ggctccgagc ctggacaggc acggtccacg
     5281 gtcggggagg ggcgcgatgg aggcggttcc ggcgagagcg cgcggctatg tggccgccgt
     5341 cgcggtgctg gcgctgctct gcctgctgcc gctgccgacg gtacgcaccc cgtggtgggc
     5401 gctgggcctg ctcaccgcgc tctacgccgc ctgcgagtac gccgtacggc gtcgcttcgg
     5461 ctccaccttc caccccgttc tgctcgccgc ggcgttcctg ctgcccgcgc cggctgccgc
     5521 gctcgttccg ctgcccgccg ccctgctctg cccggtcgag caccggcccg ccctgctgcg
     5581 gcggctgtgg cgggccgcgc ggcccgcgct cgccgtgtgg ggcgccgcca aggtgcactg
     5641 gacgctcggc ggccgggacg ccgtcgtcgg ctccgacttc ccctacgccc tgctgcccgc
     5701 aggcgcggcc gtcctcgcct tctgcctgat cctcaccgtc ctcgacggcg gcatcctcgc
     5761 cttcgccgaa cgcgtacccc tgcgccgggc ctggcgcggg ctgctgtccc gctcgctcgc
     5821 gccggtcgcc gtgcacggac tcgccgggct gatgatggcc gtgctgtggc gcagcccgta
     5881 cggcccggtc gccgcgctgc tcgtactgct gccgatgtgg gtctcctggt ggatcttcgc
     5941 ccagtaccac cgcgaacgcg ccgcccacca ggccaccatc cgggccctcg tacaggccgt
     6001 cgacatcaag gacggctaca cccgcggcca cagcgaacgc gtcggccagg cctccgtgct
     6061 gatcgcgcgc gaactcggca tggacgacga ccgcgtggag gtgctgcgct tcgccggcat
     6121 cctgcacgac gtcggcaaac tcggcgtccc cacccggctg ctgcgcaagg aggggccgct
     6181 gactcccgag gagcgccgga tcatcgaact gcatcccgag tacggccatg agatggtccg
     6241 cgggatctcc ttcctcggcg aggcccgcgc cgcgatcctg caccaccacg aacgcctcga
     6301 cggcagcggc tacccctacg gcctcgccgg ctccgggatc cccgagtgcg cccgggtcgt
     6361 cgccgtcgcg gacgccttcg acgcgatgac ctccacccgc tcctaccgcc gggcccggcc
     6421 cgtcgagacg gctgtcgccg agctggagcg ctgcgccggt acgcagttcg acccccggat
     6481 ggtcgaggcg ctggcccggg ccctgcgccg tcagggctgg catcccacgg tcaccgccga
     6541 cgaaccggcg cacgagacgg caccccggca gcgggcggcc ggcaccggga caccccggtg
     6601 accgccctgc ggctgatcca cggcgccgcc gccctcaccg cggccggatc cctcgccgcc
     6661 actctcggca ccggactcac gggccggggc gtcgcgctcg ccttcggggt gctcatagcc
     6721 gtcggtgagc tgacccggtg gagcgacgcc gaggcgggcc gggccgcgcc gctggccgcc
     6781 gcgggctcgc tggcgtacgc cctgctcggc gacgacgccg gacggcccac cggacatcac
     6841 gccgaccagg tcgtcaccgt cgtcctcgtc gcctccgtgc tcggtgccgt cccgcacatc
     6901 tggtccggtc gcacccccac cctcgaccac ctcgcccgcc gcgtcctcac cgtcggattc
     6961 gccgccgtct gcttccaacc cctgtacaac cagcgcctgt tcgcctcctg gaacggcccc
     7021 gcctacgccc tgctcctcat cgccctgctc ggcctcaccg gcctgtgcga cgcggtcctg
     7081 gccgccgccc tcgcccactg ccgcacccac tggccgttcg ccccgctgct gcgcgaggaa
     7141 ctgcgcggac tgctcgggat cggctccgcc gtcggcgcga ccggcgcggt gatggcgctc
     7201 gcggtcgccg tcgtcggcct gtgggcgctg cccgtgttct gtctgcccct gctgctcacc
     7261 cagctgtccg tgcggcggta cgccgccgtc cgcgccacct accggcagac catcgcctcc
     7321 ctcgcccgcg ccaccgagat tgccggctgc acccccacgg gccacgcccg ccgggtcgcc
     7381 gcgctcagcc tcgccgtcgg ccgcgatctc gggctggccg gaggcgaact gaccgttctg
     7441 gagtacgcgg ccctcatgca cgacatcggc cagctcagcc tcgtcgaccc ggtcccggcc
     7501 ggtgccacgg ccgggctgcc gccggcgcag cagcgccgga tcgcgctgct cggcggagcc
     7561 gtggtccggc agaccggggt ggacgcggcc gtcgccgtcg tggtcgagcg gcaggccgac
     7621 ccgtgccggg aacagcccct ggccgcgcgg atcgtccggg ccgtgaacgc ctatgaggag
     7681 aagacccggg acgccggccc cgaaggcccc ttgcgggcac tggaggagct gcggctcacc
     7741 gccgccgggg actacgcacc ggaggtggtc gagtcactcg cccgggtgct ggcccagccg
     7801 cgtggctggt gccggaccgc gccggcgcaa ggggacggga gacatacggc actgtctgac
     7861 cccaccctcg gctgggtaac ccatgggtaa tgagcgcctt tcccaccgta cgtggttgga
     7921 tgcgagggag agggtgtccg ggggcacaag ccagcccact gtgcggaact ggaactggca
     7981 ggcgggaatc gtgaggatct tcggcaaggg acggcaccgg ccctccgcct cctggcggca
     8041 ggccaccgac cgagcgttca cgctcatcgg agacggccgc tacgaggacg cgggcgagct
     8101 gctgacgcgg gccgccgacc tggaaccctg gctgtcggag tcgtggttca accttgccct
     8161 gctgcacaag ttccggcacg actgggagca ggcccgcgcg gccggactgc gcgccgtcgc
     8221 cctgctggac cgggagaccg gaacgcccga ctggtggaac gtcggcatcg ccgccaccgc
     8281 cctgcaggac tggccgctgg cacgccgcgc ctggcaggcg tacggcctga aggtgcccgg
     8341 cggtgccacc acggccgggg aaccggccgg catggagctg ggcagcgcgg ccgtgcggct
     8401 ctcgccggag ggcgaggccg aggtcgtgtg gggccgcagg ctggacccgg cgcggatcga
     8461 ggtgctgtcc atcccgcttc cctcctccgg acgacgctgg ggcgaggtcg tgctgcacga
     8521 cggcgtcccg cacggcgagc gcacgacgtc cgccggccat gcctacccgg tcttcgacga
     8581 gatcgagctg tgggcgccct cgcccgtgcc gacctgggtg gtcctgctgg aggcggccac
     8641 ggaggcggac cgggacgcgc tggagcagct ggccgccgac gccgggttcg ccgcggagga
     8701 ctggtcctcc tcggtgcggc tgctgtgccg gatgtgctcg gagtcccgga tgccctccga
     8761 cgagggcgag ggcgtgcatc tggatccgca cgaccacagc gagcccggtc accccggccc
     8821 gctgggccac cggacggacg ggcagctgtg ggtgccggag cgggagtgcg gggtcgcggc
     8881 gccggcctcc ctcgtgcggg ggctgctgga cgggtggatc gcggacagcc cggactccag
     8941 ggactggcgg gatctcgaag aggtttgctg agccgccgat gaccagccac ctttagtctg
     9001 tactcgagac tttttcgctc gggacttttc caaggttgca ggaaggcgta cgtcggtcat
     9061 ggcgcagcag gacaccgatc agcagcacgc gggcgtgctc cccgtcgacg acgagggcta
     9121 tgtcgtcgac acggaggact gcgaggagcg cgagaaggcc tggcgggagc gcggggcctc
     9181 gcggccgatc acggtcgtcg gcaacccggt gctgcacaag gagtgcaggg acgtcaccga
     9241 gttcggcgac gagctgcagc agctggtcgc ggacatgttc gcgagccagc gcaccgccga
     9301 gggcgtgggc ctggccgcca accagatcgg tgtcgacctg aaggtcttcg tctacgactg
     9361 cccggacgac gacggtgtcc ggcacaccgg tgtggtgtgc aaccccaagc tggtcgagct
     9421 ggcggccgac aggcgccggc tggacgacag caacgagggc tgcctgtccg tgcccggcgc
     9481 ctacgcgccg ctcgcgcgtc ccgactatgc cgaggtgacc ggccaggacg agcggggcaa
     9541 cccgatcaag gtccgtggca ccggctactt cgcgcgctgt ttgcagcacg agaccgacca
     9601 cctctacggc tacctgtaca tcgaccggct gtccaagcgg gaccgcaagg acgcgctgcg
     9661 ccagatggcc gagaacgagc cacgttatcc ggtgatcgcc aacgactagg ccccatcgag
     9721 ccgttgggac gcccggccgg gatcactccc ggtcgggcgt ccttcgtatg gccgggcttc
     9781 gctcatccgt gcgtcgtaca actgatcccg tccggccccc tagtgatccc taaccggtca
     9841 cgcaaggggg gattctcggc accttggggt agtgagtgga gcaaatccgt tcccatgacg
     9901 gtcagttgtg gtgctgaatg gagcggcggg gatacgcaac ggcgcacgcc cggcacaaca
     9961 ggaggggtgt gcgctcctgg cggctgagag gggtttgttc gtgcaagctt tcccacacag
    10021 caccacagcg acaccgacgg cggtcgtagt accaccctca ctggcactcc cggtgatcga
    10081 gtccgccttt ccccggcaac tgcatccgta ttggccgcag ctccaggaga agacacggct
    10141 ctggctgctg gaaaagcggc tcatgccggc gggcaaggtg caggaatatg ccgacggact
    10201 gtgctacacc gacctgatgg cgggcttcta cgtgaacgcc gccgacgagg tcctgcaagc
    10261 catcgccgac tacagcgcat ggttcttcgt ctgggacgac cgccatgatc gcgacatcgt
    10321 gcacggccgg gtgggcgact ggcggcggct gcgctaccgc ctgcacgcgg ccctcgacgc
    10381 acccaggcac catctgcacc atccggaccc cttggtcgcg gggttcgcgg acagtgtgct
    10441 gcggctgtac ggcttcctgc cgcgcacctg gaaccagcgg ttctcccggc acttccatac
    10501 cgtgatcgag gcctacgacc gggaattccg caatcgaacc gagggatatg tgccgggcgt
    10561 cgaggaatat ctcgccctgc gtcggcacac cttcgcccac tggatatgga cggatctgct
    10621 cgaggtgagc gccggatgcg aactcccgga cgccgtgcgg aagaacccgg cctttcgccg
    10681 ggccgcactg ctcacccagg aattcgccgc ctggtacaac gatctgtgct cgctgccgaa
    10741 agaaatagcg ggcgatgagg tccacaatct cggcatctgc ctcatcagcc acgagggact
    10801 gactctcgaa gaagccgtcg acgaagtgag gcggcgtgtg gaggagtgca tccgagactt
    10861 catcgaggcc gagcaggaag ccctgcaatt cgccgacgca attgccgacg gaagcatccg
    10921 gggaaaggaa ctgagcactg cggtgcgaga cagcgtcggc aatatgcgga actggttcag
    10981 ctccgtctac tggttccacc acgagtccgg ccggtacatg gtcgacagct gggacgacca
    11041 gtccacgccc ccgtacgtca ccaacgaagc ggtaggtgag aaatgaccct cgactctgtg
    11101 gagcccgtga ccaccgaggc ggccgagctg cgcgagccgc cgctggccgg cggtgccgtg
    11161 ccggtcctcg ggcacggcct gaagctcgtc cgcgacccgc tcgccttcat gtcgggcctg
    11221 cggaaccacg gtgacgtcgt acgcctgaaa ctgggcccca agacggtgta cgccgtcacc
    11281 acgccggcgc tcaccggtgc gctcgcgctc agccccgact tcaagatcga cggcccgctg
    11341 tgggagtccc tcgaggggct gctcggcaag gagggcgtgg ccaccgccaa cggtccccgg
    11401 caccgccgcc agcgacgcac catacagccc gcgttccggc tcgacgccat ccccggctac
    11461 gggccgatca tggaggagga ggcgcatcgg ctcaccgagc gctggaaacc cggtgagacc
    11521 gtcgactgca cctcggagtc cttccgggtc gccgtgcgca tcgccgcccg ctgcctgctg
    11581 cgcggcgagt acatggacga gcgtgccgag cggttgagcg cggacctcgc cacggtcttc
    11641 cgcggcatgt accgccggat ggtcgtcccg ctcggaccgc tgtaccgact gccgtttccg
    11701 gccaaccgcg aattcaaccg ggccctggcc gatttgcatc tcctggtcga cgagatcgtg
    11761 gccgagcgga gggcatctgg tcaaaagccg gacgatttgc tgacggcatt gctggaagcg
    11821 aaggacgaca atggcgaccc catcggggaa caggagatcc acgatcaggt cgtcgcgata
    11881 gtcaccccgg gcagcgaaac ggtggcctcc acgatcatgt ggctgctcca agtccttgcc
    11941 gcgcacccgg aacacgcgga gaaggtacgg accgaggtcg aatccgtgac cggtggtcga
    12001 cccgtcgcat tcgagcacgt ccgcgcactc acccacacca acaatgtcgt cgtcgaggcc
    12061 atgcggctca ggccggccgt atggatattg acgcggcgcg cggtgaccga aacctcactc
    12121 ggcggctatc gcattccggc cggggcggac atcgtctaca gcccgtacgc catccagcgc
    12181 gacgcccgct cctacgaccg caacctcgac ttcgaccccg accggtggct tccggagcgg
    12241 gccaagcagg tgcccaagca cgccatgagc cccttcagca cgggcaaccg caagtgcccc
    12301 agcgaccact tctccatgac ccagctgacc ctgatcaccg cggcgatctc ggcgaagtac
    12361 cgcttcgagc aggtcaccgg gtccaacgac agcacccggg tgggcatcac gctgcgcccg
    12421 cacgacctgc tgctgcgacc gatgccctgg tgacccaggg ggccacacct gataccggcg
    12481 tgcgctcacg cggcgtgggg gccgcggaac gtgcgccggt aggcgttcgg ggtggtgccg
    12541 agcgcccgga cgaactgatg ccgcagcgcc gccgccgtac cgaacccggt gcgccaggcg
    12601 atcgcgtcca cggtctcgtc ggtcccctcc agcaacgcct gggcgcgcag cacccgttgg
    12661 cgcagaatcc agcggtacgg cgtggtcccg gtctcctgct ggaagcggcg ggcgaaggtg
    12721 cgtggcgaca tgtgcgcgcg ggcggcgagc tgctcgacgg tcacctccgc ctcgaggtgc
    12781 tcctccatcc acaccagcac ctcgccgacg gtgtcgcacg agcctctggg cagcggccgc
    12841 tcgatgtact gtgcctgccc gccgtcccgg tgcggcggta ccaccatccg ccgggcgatc
    12901 ttgttggcga cctccgggcc ctgctccttg cgcacgatgt gcaggcaggc gtcgatcccg
    12961 gcggccgtac cggcggacgt gatcaccgga tcctcgtcga cgtacagcac atccggctcg
    13021 acggctatcc gcggatagcg ccgggccagc tgctcggcgt gatgccagtg caccgcgcac
    13081 cgccggtcct ccagcagccc cgcggcggcc agcaggaaca cccctgagca gacgctcagc
    13141 acccgcgcgc cccgcccgac ggcccgccgc agggcgtcca gcagctcctc gggatagtcc
    13201 cgttcgacgt aggagtcacc ggccggtacg gcgatgaggt cggcctcctc cagccgctcc
    13261 agcccgtagg gcgtggacac ggtgaacccg cagcgggtgc cgagcgtcgg cccctcggcc
    13321 gagaccacgg cgaagtcgta gaccggcagc ccctcgtccc ggcggtcgat gccgaagacc
    13381 tcgcacacga cgcccagttc gaagggatgc accccctcga gcaatacggc ggccacgttc
    13441 ttcagcatgc tgccagtgtg cctcgtcagt ggcagtattt cgagggtgtc cggcagtcct
    13501 gccactgccg gtcagcagtg tcgggcgcga cagtggtgtc atgaacggaa accagatcca
    13561 aggcctcatc ggcatggtgc tcaccctcgg aatcctgctc ctcctcgtcc tcccctccgc
    13621 cgtcggtgcc gtgcgcgaac ggcgcatcga ccgacagctc agggaggccg ggaagagagc
    13681 gggaagagag caggatcaga agtcctcgtc caggtcgacg gtgccctcga ccgcgacctg
    13741 gtacgccgac ggacggcgct cgaagaagtt cgtcagctcc tgaacgccct gcagctccat
    13801 gaaggagaac gggttctccg agccgtacac cggggcgaag ccgaggcgcg tgaggcgctg
    13861 gtccgcaacg cactccaggt actggcgcat cgactcggtg ttcatgcccg gcaggccgtc
    13921 accgcacagg tcgcgggcga actgcagctc ggcctcgacg gcctccttca gcatgtcgac
    13981 gacctcctgc tgcagctcgt cgtcgaagag atccggctcc tccttgcgga cggtgtcgac
    14041 cacgtcgaag gcgaacgaca tgtgcatggt ctcgtcgcgg aacacccagt tggtgccggt
    14101 ggcgaggccg tgcagcagac cccggctgcg gaaccagtag acgtacgcga aggcgccgta
    14161 gaagaacagg ccctcgatgc acgcggcgaa gcagatcagg ttgagcagga agcggcggcg
    14221 gtcggccttc gtctccagcc ggtcgatctt gtccaccgag tcgatccact tgaagcagaa
    14281 ctcggccttc tcgcggatgg acgggatgtt ctccaccgcc gcgaaggccg ccgcccggtc
    14341 ctccgggtcg gggaggtagg tgtccagcag cgtcaggtag aactggacgt gcacggcctc
    14401 ctcgaagagc tgacggctca ggtacagccg cgcctcgggg gagttgatgt gcttgtacag
    14461 cgtcagcacc aggttgttcg cgacgatcga gtcacccgtc gcgaagaagg cgaccagccg
    14521 gccgatgagg tgctgctcct cgggcgtcag cttcgcgagg tcggcgacgt ccgagtggag
    14581 gtcgacctcc tcgacggtcc aggtgttctt gatcgcgtcc cggtagcgct cgtagaagtc
    14641 cgggtagcgc atggggcgca gagtcagctc gaagcccggg tcgagcaggt tggcgttacg
    14701 ggtggtggtg ctcattactg gcaggcctcg caggactcgg ggttttccag ggagcaggcg
    14761 acggcgtcgg ggtcggcggc ctgctggacg gggatgccgg cggtgctctg cgcctgggcc
    14821 gcgcgggcga tccgcgtcgc cgggcgggag cgcaggtagt acgtcgtctt caggcccgac
    14881 ttccaggcgt acgcgtacat cgaggagagc ttgccgatgg tcggcgtctc caggaacagg
    14941 ttcagggact gcgcctggtc caggaacggg gtgcgggccg cggccatgtc gatcaggccg
    15001 cgctgcggga tctcccacgc cgtgcggtac agcgcccgca cctcctcggg gatccacacg
    15061 aaaccctgca ccgagccgtt ggagtcgcgc agcgcctcac gggtgcgcgc gtcccacacg
    15121 ccgaggttct tcaggtcctg caccaggtac gagttgacct gcaggaactc accggacagc
    15181 gtctcgcgct tgaacaggtt cgacacctgc ggctcgatgc actcgtacac gcccgcgatg
    15241 gaggcgatgg tcgccgtcgg ggcgatggcg agcagcagcg agttgcgcat gccgacggac
    15301 gcgacgcgcc tgcggagcgc gtcccagcgc tcgggccagg tcagctcggt gtcgtagtgg
    15361 tccgggtgca gcacgccctg ggccgtacgg gtcttctccc aggccggcag cgggccgctg
    15421 cgctcggcga ggtcggtgga ggcctcgtac gcggcaagca tgatccgctc ggcgatccgc
    15481 gtcgacaggg ccctggcctc ggcggagtcg aagggcagac gcagcttgaa gaagacgtcc
    15541 tgcagaccca tcgccccgag gccgaccgga cgccacctgg cattggagcg gcccgcctgc
    15601 tcggtcgggt agaagttgat gtccacgacc cggtcgagga aggtcacggc cgtgcggacg
    15661 gtctcgtcca gccgctccca gtcgatgtcg ccgcgcgccg cgtcgacgaa ggcacccagg
    15721 ttcacggatc ccaggttgca gaccgccgtc tcgccgtcgt ccgtgacctc caggatctcc
    15781 gtgcagaggt tggaggagtg gaccacgtga ccgggcaggg ccgtctggtt ggcggtgcgg
    15841 ttggccgcgt ccttgaaggt catccagccg ttgccggtct gcgcgagggt gcgcatcatg
    15901 cggccgtaca gctcgcgggc cgggatggtc ttcttcgcca ggcccgcctg ctcggccttg
    15961 cggtaggcgg cgtcgaactc ctcgccccac aggtccacca gctccggcac gtcggccggg
    16021 gagaacagcg accactcggc gtccgcgttc acccggcgca tgaactcgtc cgggatccag
    16081 tgcgcgaggt tcaggttgtg cgtacggcgg gcgtcctcac cggtgttgtc ccgcagctcc
    16141 aggaactcct cgatgtcgga gtgccaggtc tccaggtaga cggccgcggc acccttgcgc
    16201 cggccgccct ggttcacggc ggccaccgag gcgtccagcg tcttgaggaa cgggacgatg
    16261 ccgttggagt gcccgttggt gccccggatc agcgaaccgc ggctgcggat acgggagtac
    16321 gacagcccga tgccgcccgc gtgcttggag agccgggcaa cctggtggta gcggtcgtag
    16381 atggagtcca gctcgtccag cggggagtcg agcaggtagc aggacgacat ctgcgggtgc
    16441 cgcgtaccgg agttgaagag cgtgggggag gacggcaggt agtcgaggcg gctcatgagc
    16501 cggtagagcg cggcgacttc gtcgacggag cgtgcggtgt cgtcctcggc gagtccggcg
    16561 gccacccgga gcatgaagtg ctgcggagtc tcgatcacct tgcgggtgat cgggtgccgc
    16621 agcagatagc ggctgtgcag ggtgcgcagg ccgaagtagc cgaagcggtc gtcggcgccg
    16681 gtgtcgatca gggcgtcgag gcgggccgcg tgcagccgcg cgaactccgc ggtgcggtcg
    16741 gcgatcaggc cctcgcggtg accgacggcc acggactcgg tgaaggacgt cacgccctgc
    16801 gagccggcct cggcgcggat ggagagggtc agtagccggg cggccagccg cgagtaggcg
    16861 gggtcctcgg agatgagccc ggcggcggcc tcggtggcca gttcgcgcaa ctccgcctcg
    16921 tcggcccggg cggaccggcc gcgcagcgcg gcggcggcga cccggccggg gtcggcgtcg
    16981 gggaggtcgg cggtcagctc ggtcagggtc cgcagcaacg cggtaccggg accgtcggtg
    17041 tccaggccgc tggctgaagc cggatctgct ggcgcgatgg tcacgtgggg ctctccctcg
    17101 ctcggcacgg gggccttgcg gagggcaggg ggcagccacg agcgcacacg cgtggcgtcc
    17161 accggcccat tccacgaggc ccggacgtcg gaaggcaccc gggccggacg gccgggcgca
    17221 cgctgccggc aggtcctcgg actgactcct gggcgcatac gcgcacaagt acaccgttgc
    17281 gggacagttc cggattcaca ccggattccc ctgcgacgac agcgaggatg agcatacatc
    17341 tagtgccggg ctgtcgtggc accaccagat gttgtgtctg ttgtgtgttg cgctggcttc
    17401 agagcgtcaa cttgtgtatg acgggaggta tgcgaaacgg gccgccgtgg gttcgtcccc
    17461 cggcggcccg ctgtggtggt gtgccgcgta cgacgtgcgt cagtgggcga cgcccaccag
    17521 ttccgtttcg acaccctggt cgcccgcgtc cgccgtgtag tcctccggcc tggtctcgtc
    17581 gatgccctcg ggggccttca cggcccgcag gacgagcgtg aggaccaccg tgaccgccac
    17641 gttgagcacg aacgccgtga agccgatgta gccgatctca ccgatgcccg ggatctcctt
    17701 cgacgagcct ccgaagtgct tctgggtcgg ggaggcgaca ccgtacgcgg cgaccgtgcc
    17761 gtagatcatg ccgaccgccc agccggtgag cagcgcccag cggtggaacc agcgggtgaa
    17821 caggccgccg accagggccg ggaaggtctg caggatccag atgccgccca gcagctggaa
    17881 gttgatggcg acggtcttgt ccatggtcag gacgaagagc agggcgccga acttcaccag
    17941 cagcgagacg atcttggaga cctgggcctc ctgcctcggc gtggcgtccg gcttgatgaa
    18001 gtccttgtag atgttgcggg tgaagaggtt cgccgccgcg atcgacatga tcgccgccgg
    18061 caccagcgcg ccgatgccga tcgccgcgaa ggccacgccc gcgaaccagt ccgggaacat
    18121 gtcctcgaac agctgcggga tcgccagctg gccgttggtg accttcacgc cggccgcgat
    18181 cgccatgaag cccagcaggg ccagcaggcc gagcatcagg gagtacagcg gcaggatcgt
    18241 ggtgttgcgg cggatcacct cacggctctt ggacgacagg gtcgcggtga tcgagtgcgg
    18301 gtacatgaag agggccaggg ccgagccgag ggccagggtg gcgtaggtcc actggcccgc
    18361 ctccggcggc gcgagcgcgc cgcgcggctt gccggtggcg gggctgacct ggctgaacgc
    18421 gtggcccgcc ttggcgaaga tgtcgtcgaa gccgcccagc ttgatcggga tgtagatgat
    18481 cgccaccgcg atgacgatgt agatcagggc gtccttgacg aacgcgatca gggcgggcgc
    18541 gcgcaggccg gaggagtagg tgtaggccgc cagcacgccg aaggcgatca gcaggggcag
    18601 gtccttcatg aaccagttgg tgttgtcccc gccgccgacc cccatcacgt ccagcacggc
    18661 ctggatgccg acgagttgga gcgcgatgta cggcatcgtc gcgaggattc cggtcagcgc
    18721 caccgcgagc gacaggccct tcgagccgaa ccggccccgg acgaagtccg aggtggtgac
    18781 gtacccgtgg cggtgcgaga ccgaccacag gcgcggcagg aaggtgaaga tcagcgggta
    18841 gaccaggatc gtgtacggca ccgcgaagaa gccggacgcg cccgccgcgt agaccgccgc
    18901 cggcacggcg acgaaggtgt acgccgtgta caggtccccg ccgagcagga accaggtgat
    18961 ccaggtgccg aacgaccgtc cgcccaggcc ccattcgtcc agcgagtgct cgttctcggc
    19021 cttgcgccag cgtgcggcga ggaagcccat gaccgtgacg gccaggaaga agaagatgaa
    19081 gacgccgagc gcgacgccgt tgaccccgtt cttcacttcg cctcaccgcc ctggggcgcg
    19141 gtcggggagc gctggtcgta ctgccacagc ttgtacgccg tcatggtgag tgcggcggag
    19201 atcggcaccc agagcatctg gtaccagtag aagaacggga tcccgatgaa cgcgggatcc
    19261 gtcttggcgt acgagccgac ccacagcatc gccacgaagg gtgcgacgag acacaggccg
    19321 atgatcacgc ggaccggtgt cacgaccggt ggtctcactt ctggtgtatc ggacatgccg
    19381 cgactccgtc ccctcgttga tcacccgggt aatgcgatca cctgtgtaat gcgcaggcaa
    19441 tctaggtgac gcaggacccc agcggaagac ctcgtccgga ttccggatcg cgggttcccc
    19501 ggtacggccg cggtgggctc tcagcggctc ggtcaccacg aagtcgcaga gtgccgcgaa
    19561 gacttcgcga gccggacagc caggtggatc ccgaatctcc cgcagcgtga tgttcgcccc
    19621 tttccgcact tccgcgcggg ccgtgtcgat cgccggatgc tcctgcagga gaccgagcgc
    19681 ctcggcgtgc agggcggggt cactcagctc tccacattct cggaaagctg tggcgcaccg
    19741 tcgggcccca ctcaatcagc gtccgtcgca agtcgatgcc gagcacgggg gccgagtacg
    19801 gggacgagtc ccggactgtt ctactcggca ggccgcttga gtcgggccac gaacttgtag
    19861 cggtccccgc ggtacaccga ccgcacccac tccaccggtc tgccctcgtg gtccagggag
    19921 tggcgggaga gcatcagcat cggcaggccc acgtcggtgc cgagcaggcc cgcctcgcgc
    19981 ggggtggcca gggaggtctc gatggtctcc tcggcctccg cgaggtggat gtcgtacacc
    20041 tcggcgaggg cggtgtagag ggacgtgtac ttcaccaggg accggcgcag cgccgggaag
    20101 cgcttggcgc tcagatgggt ggtctcgatg gccatcggct cgccgttggc catgcgcagc
    20161 cgctcgatgc gcagcacgcg cccgccggcc gagatgccga gcagatcggc gagccgctcg
    20221 tcggccgtga tgtacccgat gtccagcagc tgcgaggtcg gctccaggcc ctgggcgcgc
    20281 atgtcctccg tgtaggaggt gagctggagc gcctgggaga ccttgggctt ggcgacgaag
    20341 gtgccctttc cctggatgcg ctcgagccgg ccctcgacga ccagctcctg cagggcctgg
    20401 cggacggtgg tgcgggaggt gtcgaactcg gcggccagcg tgcgctcggg cggcactggc
    20461 gtgcccgggg cctgcgtctc cgtcatgtcg agcaggtgct tcttcaggcg gtagtacttg
    20521 ggcacgcgag ccgtacggac ggtcgtgccg gcctcgttct ccgcactgct gacgtcggtg
    20581 ctcatgctct gccttcccgg ctccggatgc cgaaagcgac cggctgacat cggccacggc
    20641 tcacatcgtg gcacggcttt gtgtgtccgg agtccacccg cacgctccgt gatctcctct
    20701 atataccgtc gcactccagg ttggtctagt ccatcgggct cggtgtgcgc tgcccgtacc
    20761 ggtatgggca acggcacggg cagcggcgta tcggtaccga cgccccgggc tagatgccct
    20821 gccagtccgg cttgttggcg taggtgtgcc ggaagtagtc ggcgagcttc agcttggacg
    20881 cggccgcctc gtcgacgacc accgtggcat gcgggtgcag ctggagcgcg gaggccgggc
    20941 agacggccgc gaccgggccc tcgaccgtcg cggcgacggc gtccgccttg ccctcgccgg
    21001 tcgcgagcag caccaggtgc cgggcctcca ggatggtgcc gatgccctgg gtgatgacgt
    21061 ggtgcgggac ctgctcgatg tcgccg
//
