LOCUS       NZ_CP047020            21210 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Streptomyces broussonetiae strain T44 chromosome.
ACCESSION   NZ_CP047020
VERSION     NZ_CP047020.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces broussonetiae
  ORGANISM  Streptomyces broussonetiae
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9735779)
  AUTHORS   Mo,P.
  TITLE     Streptomyces sp. strain T44 isolated from rhizosphere soil of
            Broussonetia papyrifera
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9735779)
  AUTHORS   Mo,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2019) College of Life Science and Technology,
            Central South University of Forestry and Technology, No. 498,
            Shaoshan South Road, Changsha, Hunan 410004, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 25-OCT-2019
            Assembly Method                   :: HGAP v. 3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 12.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009796285.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 17:56:09
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,022
            CDSs (total)                      :: 8,931
            Genes (coding)                    :: 8,515
            CDSs (with protein)               :: 8,515
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 416
            CDSs (without protein)            :: 416
            Pseudo Genes (ambiguous residues) :: 0 of 416
            Pseudo Genes (frameshifted)       :: 171 of 416
            Pseudo Genes (incomplete)         :: 334 of 416
            Pseudo Genes (internal stop)      :: 29 of 416
            Pseudo Genes (multiple problems)  :: 110 of 416
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:31:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3972487
            Orig. end                         :: 3993697
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP047020.1.
            Bacteria and source DNA available from Zhao YL.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21210
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="atropopeptide"
                     /region_number="15"
                     /rules="atropopeptide_p450"
                     /tool="antismash"
     cand_cluster    1..21210
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="atropopeptide_p450"
                     /kind="single"
                     /product="atropopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21210
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11210](-)"
                     /cutoff="10000"
                     /detection_rule="atropopeptide_p450"
                     /neighbourhood="10000"
                     /product="atropopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11210)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="atropopeptide_p450"
                     /neighbourhood="10000"
                     /product="atropopeptide"
                     /protocluster_number="1"
     misc_feature    complement(692..707)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.66"
                     /tool="antismash"
     gene            complement(1031..1720)
                     /locus_tag="GQF42_RS18425"
                     /old_locus_tag="GQF42_18425"
     CDS             complement(1031..1720)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018532409.1"
                     /locus_tag="GQF42_RS18425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_18425"
                     /product="response regulator"
                     /protein_id="WP_158921315.1"
                     /transl_table=11
                     /translation="MIRTLVVDDDFRVSHIHCDYVSRVRGYEVVGEAATVAEALEAAHD
                     LRPDLLLLDIFLPDGSGLDVLRRLTGDAGGARPDAFVITADRDIASVRTAMKLGAVGYL
                     VKPFGAADLAERLTSYRELQHRVDTLGETTETEQADVDALFSAVRPPAVPRVPAKGHSA
                     PTLALVQQTLRTAHRDLSAAEAAELTGVSRATAQRYLSYLVKEGMVRLILRYGATGRPE
                     HRYRIAS"
     gene            complement(1717..3372)
                     /locus_tag="GQF42_RS18430"
                     /old_locus_tag="GQF42_18430"
     CDS             complement(1717..3372)
                     /EC_number="2.7.13.3"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014145311.1"
                     /locus_tag="GQF42_RS18430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_18430"
                     /product="sensor histidine kinase"
                     /protein_id="WP_158921317.1"
                     /transl_table=11
                     /translation="MTPIRIRIGRGGRGRLSARILVSQLAILALTGVIGFALFAFAQRS
                     ALDRTYEERAVAIAKTTAADPQIRRAMQDGGGAVVQAVAERIRQSSGASYVVVIDLHGV
                     RHSHPMPQLVGSPVAEPIVARDGQPHVGTDQGATGRSANGRVPLYGPTGELVGEVSVGI
                     PERDVLGELWHELLTFAVYAAIATALGAAAAFLLARRLKRTTFGLELEEIAGLLQDREA
                     MLHGIREGVLAFAPDGRISVVNDEARRLIGLGTALGSTLDEVLPDGRLRRALDGTLTGT
                     DISVLTDEHCLVVNRMPVTLHGRALGAVVTVRDRTELVGLLRELDSVRGLTDALRAQQH
                     EFTNRMHTLAGLLDIGAYDDAYDLAVESAGAGQALTEFVRGRIGNPLMVGLVVAKTTVA
                     AERGVWVELADDSALGADPPQLRLLLTIVGNLLDNAIDAAGDGPPPADGRTVRLALTED
                     ERGTTVRVADTGPGIPPGARESIFEDGWSTRPDRGTARRGLGLALVHRLVSRHGGTITV
                     SEGPGAVFTVRLPAPAVRPKNRFAEALPVGGDRR"
     misc_feature    complement(3531..3548)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.13"
                     /tool="antismash"
     gene            3609..4448
                     /locus_tag="GQF42_RS18435"
                     /old_locus_tag="GQF42_18435"
     CDS             3609..4448
                     /EC_number="7.6.2.14"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009062808.1"
                     /locus_tag="GQF42_RS18435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_18435"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_158921319.1"
                     /transl_table=11
                     /translation="MASSSAGAAVREDAHIEISGLTKRFLTPAGEVFTALEGVSFTVEP
                     GQFCAVVGPTGCGKSTTLGMVSGLDRPSEGSVKVGGREVDGITDGVSFMFQADALLPWK
                     SVLGNVLMGPVFRGVPKQQAQTAARDWLRRVGLSGFEDRYPHQLSGGMRKRVAMAAALI
                     NEPKILIMDEPFGALDVQTKAIMSTELLGLWEQIRPSVIFITHDLDEAVALADRVVVMT
                     SSPGSVKAVFDIDLPRPRGSVQEIRFQPRFIELQQQIWETLREEVERAYARTAGGKA"
     gene            4445..5323
                     /locus_tag="GQF42_RS18440"
                     /old_locus_tag="GQF42_18440"
     CDS             4445..5323
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014179388.1"
                     /locus_tag="GQF42_RS18440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_18440"
                     /product="ABC transporter permease"
                     /protein_id="WP_158921321.1"
                     /transl_table=11
                     /translation="MSTTSTASAAQVAGGKQSSAAAAAKQAARRRVASVWAGRIGIAVF
                     VIGGWQAFTTWGIVDPFFFGQPSGIWKRLVDLFQHGTEFGSFYANIWTTIQEALIGFAV
                     GAVAGVVFGVALGQSRYLSDVLGPYIKMVNAIPRIVLGSIFIVAFGIGVTPKILLAAVL
                     VFFIVFFNAFQGVREVDRNILANARVLGASQLQIVRHVIVPSALTWIIASLHSAFGFAI
                     VGALVGEVLGAQSGLGLVIKTAQNNFDPNGVFATMLVISVIVLGAEWLIAKLEHRLLSW
                     RPPAPTEANSL"
     gene            5403..6482
                     /locus_tag="GQF42_RS18445"
                     /old_locus_tag="GQF42_18445"
     CDS             5403..6482
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019061025.1"
                     /locus_tag="GQF42_RS18445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_18445"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_158921323.1"
                     /transl_table=11
                     /translation="MLKRALTASIVTALTLGAATACSGSSGGSSASGGTPTVKIMVGGI
                     DKQIYLPYQLADNLGFYKKYGVNVVLSTEQDGGTGAEDAMASGQVDMAGAWYNHTIDFQ
                     AKGKAVEDVIQLSGAPGEREMCTPKSGVHSAADFKGKTLGVTDLGSGTDTLTKFLAAKK
                     GLKTGDFSRIGVGAGSTAVAALQNGKTACVMTTQPTVAAMEKKGVGTSAIDLATTQGAT
                     AALGSAWPAASVIARTDWVNSHKDAVQKVVDALVATMHWINTHSAADIADKLPQSFVQN
                     QLVTKADYVTALNQDKGQFLPDGLMPAGGPKTVLATEELVGNATSSIDLSKTFTNDFVL
                     QANKLEGLKTTTTPAGANG"
     gene            complement(6534..7502)
                     /locus_tag="GQF42_RS18450"
                     /old_locus_tag="GQF42_18450"
     CDS             complement(6534..7502)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007502470.1"
                     /locus_tag="GQF42_RS18450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_18450"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_158921325.1"
                     /transl_table=11
                     /translation="MPADLDPRLLRAFVAVAEELHFTRAAARLYVAQQALSRDVRRLER
                     ELGAELFLRSTRQVTLTADGERLLPYARRVLAAQDELLAACTSFGQARPLLVDLNSPGL
                     VTGRRVLHRARELAPDCELMARYESGLTGAAEQILSGRLDVSFGRFAGLDPALRSGLER
                     QPVRYEPMAVVLPEEHPLAALPEIPVAGMTGETVYAGAGNPRTLEWTDLASRLFAQYGI
                     RLAPPLPLAVGDEEFERIMGKTRYPVLAVVDFPALPRTVRRPLVDPVPLSPVSLVWRRG
                     LVHPGLDALRGAAARIAAAQGWLRRPEGSWLPAADEMTATG"
     gene            7587..8813
                     /locus_tag="GQF42_RS18455"
                     /old_locus_tag="GQF42_18455"
     CDS             7587..8813
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018549711.1"
                     /locus_tag="GQF42_RS18455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_18455"
                     /product="MFS transporter"
                     /protein_id="WP_158921327.1"
                     /transl_table=11
                     /translation="MPSVISTPTRRSAYLRLFSLPGTRAFTTGNLLARLPMGMFSVSAV
                     VMIAGSRGSYALAGAVTATGLAATGLAGPWIARLIDRHGQARIAVPATLLSVLGSLALL
                     LCVRFGAPDWTLFAAYAATAATPNIGGLSRARWAHLLRDDSGALHTANAFEQAADELCF
                     MLGPVLASFLTGTFFPEAGTLTGAVLLLAGMLLFTAQRATEPPVGARSKAPSPLRSPGI
                     RPLLACFVATGMVFGSMEVGTIAFADAHGHRAVAGAVLALQAAGSCAAGLVFGARRPAG
                     VRLGHCLAAMAVLMTLPWAAAGAAGSLPGLAGALLVAGMATAPTMVTAMTLVQRRTPAD
                     RLNEGMSLVVTGLLTGIACGSAAGGWTAQHLSPGTALAVPATAAALALLVHTASTGARR
                     NVSADGPED"
     gene            complement(8788..10014)
                     /locus_tag="GQF42_RS18460"
                     /old_locus_tag="GQF42_18460"
     CDS             complement(8788..10014)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385740.1"
                     /locus_tag="GQF42_RS18460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_18460"
                     /product="cytochrome P450"
                     /protein_id="WP_233273380.1"
                     /sec_met_domain="p450 (E-value: 9.4e-26, bitscore: 89.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLPEMSYDTETVDESFAGRPHDVYRRWREEGGVRKVRFSGAAPL
                     AGWVVTGHAACRAALADPRLSKDGATEAYARHEGLPGGGPGGALTTHMLNSDPPRHTRL
                     RRLVQQAFTQRRVAELRPRIEAHVTALLDAVDRADEAGEVDLIARFALPLPLAVIFELL
                     GADPGAHGILQVRGHTVGGDGGDGEVSVPTAETMLERLRELVEDKRAHPGDDLLSALLA
                     ARADGERLTGQEVTSMAFLLVIAGHQTTVNLVANGLYALLTHPGQLAAVRADPALVPGL
                     TEEVLRHESPFALASLRYTTEPVTIAGTTIPAGEFVQIALAAANRDPAVFADPDRFDVT
                     RDASRHLAFGHGIHHCLGAPLARLQAEIAFTHVLRRFPGLRLAGRERAPEWQDNPRHRG
                     LLSLPVRLR"
     gene            complement(10001..11044)
                     /locus_tag="GQF42_RS18465"
                     /old_locus_tag="GQF42_18465"
     CDS             complement(10001..11044)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     atropopeptide: atropopeptide_p450"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (MITE)
                     MITE0000172: Biaryl bond formation (82% identity)"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003963544.1"
                     /locus_tag="GQF42_RS18465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_18465"
                     /product="cytochrome P450"
                     /protein_id="WP_158921329.1"
                     /sec_met_domain="atropopeptide_p450 (E-value: 2.6e-184,
                     bitscore: 611.1, seeds: 287, tool: rule-based-clusters)"
                     /sec_met_domain="p450 (E-value: 2.6e-16, bitscore: 58.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRTLFHPRLAALFRDHLGQDVFRLEPDTVGIAGYEVADRILAAR
                     RATETERPTFKPLHGRSISRGEASSVMRTIGGDVREALKRSRPGPEDVDLSGVWPLRGH
                     LFLRDLILGKDPYRLRILMSRNLELTPKLTWAVIAAGAALPGRVGRRGAPLTAIAGLTA
                     DAGGYHERRYAMGMYRRAAAPVCFTVSTLVANALWLGSPFDPDTPNRHILHESMRLLPP
                     SWNILRNASPEYPAVDDRIGAGDDVLLLPLLTHRDPKLWEDPHEFRPERWESLDPDTAP
                     GYLPFGHSSERCWGRHMVMPLAELLLDLIRGSGLAVSPDQRSAKVPLVGLLGVEDVQVT
                     KVRRAAA"
     gene            complement(11130..11210)
                     /locus_tag="GQF42_RS47710"
     CDS             complement(11130..11210)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     atropopeptide: atropopeptide_precursor"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038372.1"
                     /locus_tag="GQF42_RS47710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tryptorubin family RiPP precursor"
                     /protein_id="WP_218161885.1"
                     /sec_met_domain="atropopeptide_precursor (E-value: 1.0,
                     bitscore: 1.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLLFAIRNKVSAQKSLKASAWYFWY"
     misc_feature    11230..11242
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.19"
                     /tool="antismash"
     tmRNA           complement(11391..11759)
                     /db_xref="RFAM:RF00023"
                     /gene="ssrA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="GQF42_RS18470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="GQF42_18470"
                     /product="transfer-messenger RNA"
     gene            complement(11391..11759)
                     /gene="ssrA"
                     /locus_tag="GQF42_RS18470"
                     /old_locus_tag="GQF42_18470"
     misc_feature    11512..11527
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.23"
                     /tool="antismash"
     misc_feature    11540..11553
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 20.06"
                     /tool="antismash"
     misc_feature    11668..11677
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 16.08"
                     /tool="antismash"
     misc_feature    11669..11682
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.73"
                     /tool="antismash"
     misc_feature    complement(11671..11684)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.86"
                     /tool="antismash"
     gene            complement(11867..12409)
                     /gene="smpB"
                     /locus_tag="GQF42_RS18475"
                     /old_locus_tag="GQF42_18475"
     CDS             complement(11867..12409)
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene="smpB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019056425.1"
                     /locus_tag="GQF42_RS18475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_18475"
                     /product="SsrA-binding protein SmpB"
                     /protein_id="WP_153535457.1"
                     /transl_table=11
                     /translation="MYVPKESQPKQGGGAAKARDGEKGGKRKIVAQNKKARHDYAIIDT
                     YEAGLVLMGTEVKSLREGRTSLTDGFVQIDRGEAWLHNAHIPEYHQGSWTNHSARRKRK
                     LLLHREEIDKLESKSQETGHTIVPLAIYFKDGRAKAEIALARGKKEYDKRQTLREKQDR
                     RESDRAIAAAKRRQRGV"
     gene            complement(12467..13651)
                     /locus_tag="GQF42_RS18480"
                     /old_locus_tag="GQF42_18480"
     CDS             complement(12467..13651)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S41"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016438125.1"
                     /locus_tag="GQF42_RS18480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_18480"
                     /product="S41 family peptidase"
                     /protein_id="WP_158921331.1"
                     /sec_met_domain="Peptidase_S41 (E-value: 1.4e-38, bitscore:
                     131.1, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGRDLFCPPRRIRRGATLTLVFAGVLVAGAATGSFPEAGQPNRK
                     PAFGPAATATTPHEDVQKAAAEAAADGKSPMEAAERAVSRSGDRWGAVYSEGEYQEFQE
                     ALDGKYTGVGLWARREQDGRIEVTRVQPGSPADRAGIRKGDRLTSVDGSKVDGRPVTDV
                     VALLRGDADDAAAGTTVTLGLERGTRAWSEKLRRASLSTDSVSVSRLPGGVTVIKIAAF
                     TKGSGDAVRAAVRQAPADAGIILDLRGNSGGLVTEAVETSSAFLDGGLVATYDVDGAQR
                     SLHADPGGATARPLVALVDGGTMSAAEMLTGALQDRGRAVVIGSRTFGKGSIQMPTRLP
                     GGSVAELTVGHYRTPLGHSVDGRGITPDLDVGQADGQAAVERAETVLGGLGDAD"
     misc_feature    complement(13154..13156)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(13719..14636)
                     /gene="ftsX"
                     /locus_tag="GQF42_RS18485"
                     /old_locus_tag="GQF42_18485"
     CDS             complement(13719..14636)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene="ftsX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004000800.1"
                     /locus_tag="GQF42_RS18485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_18485"
                     /product="permease-like cell division protein FtsX"
                     /protein_id="WP_158921333.1"
                     /transl_table=11
                     /translation="MRAQFVLSEIGVGLRRNLTMTFAVIVSVALSLALFGGSLLMSDQV
                     STMKGYWYDKVNVSIFLCNKHDAESDVNCAKGAVTEDQKKQILADLHNMPIVEKVSYES
                     QDDAYKHYKAQFGNSPLASSLTPDQMQESYRIKLKDPQKYQVVASAFNGRDGVQSVQDQ
                     KGILDNLFQLLNLMNRGALGVMAMMLIVALLLIVNTVRVSAFSRRRETGIMRLVGASGF
                     YIQAPFIAEAAVAGLIGGGLACVALLVGRYFTIDHGMDLAHKLQLINFVGWDAVLAKLP
                     LILATSVLMPSLAAFFALRKYLKV"
     gene            complement(14671..15360)
                     /gene="ftsE"
                     /locus_tag="GQF42_RS18490"
                     /old_locus_tag="GQF42_18490"
     CDS             complement(14671..15360)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /gene="ftsE"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006349025.1"
                     /locus_tag="GQF42_RS18490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_18490"
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="WP_158921335.1"
                     /transl_table=11
                     /translation="MIRFDNVSKVYPKQTRPALRDVSLELEKGEFVFLVGSSGSGKSTF
                     LRLILREERCSHGQVHVLGKDLARLSNWKVPQMRRQLGTVFQDFRLLPNKTVAENVAFA
                     QEVIGKSRGEIRKSVPQVLDLVGLGGKEDRMPGELSGGEQQRVAIARAFVNRPKLLIAD
                     EPTGNLDPQTSVGIMKLLDRINRTGTTVIMATHDQNIVDQMRKRVIELEKGRLVRDQAR
                     GVYGYQH"
     misc_feature    15431..15451
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.22"
                     /tool="antismash"
     gene            15599..15790
                     /locus_tag="GQF42_RS18495"
                     /old_locus_tag="GQF42_18495"
     CDS             15599..15790
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003990616.1"
                     /locus_tag="GQF42_RS18495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_18495"
                     /product="hypothetical protein"
                     /protein_id="WP_023550109.1"
                     /transl_table=11
                     /translation="MTYDRLVCANCAAPVSEGRCPVCRANRERLQQEGFLGGVNPMALI
                     ALLAVLIAAVALLAHQTA"
     gene            complement(15894..16940)
                     /locus_tag="GQF42_RS18500"
                     /old_locus_tag="GQF42_18500"
     CDS             complement(15894..16940)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010355974.1"
                     /locus_tag="GQF42_RS18500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_18500"
                     /product="hypothetical protein"
                     /protein_id="WP_158921337.1"
                     /transl_table=11
                     /translation="MTKKTRIRVARIAAGAVIAAGASLTAAGAASAAGIDVQAGPISLG
                     VHTDAGNDDGGTDGGGCPVAVCTDGGTTDGGTNGGSTNGGTTDGGTTVGGTVSIGGTTD
                     GGSTDGGSTNGGSTTGGTTDGGSTNGGTTDGGSTNGGTTDGGSTNGGTTDGGSTTGGTA
                     DGGSTTGGTADGGSTTGGTADGGSTTGGTADGGSTTGGTTTGGTTTGGSTTGGSTTGGS
                     TTGGTTTGGSTNGGSTTGGSTTGGSSTTGGSSTGGSSTSGGSGSTGGNNDNPQGGSGKA
                     TQDAGSSTLTDTGSGNKAQAQGGDKQLAETGAGPTEFLLIGAATMIAGGIGFRVLPRLM
                     NGRGGAAA"
     misc_feature    17088..17102
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 18.08"
                     /tool="antismash"
     misc_feature    17093..17106
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.36"
                     /tool="antismash"
     misc_feature    17165..17182
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.48"
                     /tool="antismash"
     misc_feature    complement(17171..17184)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.86"
                     /tool="antismash"
     misc_feature    complement(17180..17197)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.44"
                     /tool="antismash"
     misc_feature    complement(17219..17239)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.99"
                     /tool="antismash"
     gene            complement(17239..18345)
                     /gene="prfB"
                     /locus_tag="GQF42_RS18505"
                     /old_locus_tag="GQF42_18505"
     CDS             complement(17239..18345)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA]"
                     /GO_process="GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="prfB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004000796.1"
                     /locus_tag="GQF42_RS18505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_18505"
                     /product="peptide chain release factor 2"
                     /protein_id="WP_158921339.1"
                     /transl_table=11
                     /translation="MAVVDVSEELKSLSSTMESIEAVLDLDRMRADVAVLEEQAAAPSL
                     WDNPDEAQKITSKLSHLQAEVRKAEALRGRIDDLAVLFEMAEEEDDPDTRAEAESELAA
                     VRKSLDEMEVRTLLSGEYDSREALVNIRAEAGGVDAADFAEKLQRMYLRWAEQRGYKTE
                     LIETSYAEEAGIKSTTFSVQAPYAYGTLSVEQGTHRLVRISPYDNQGRRQTSFAGVEVL
                     PVVEQSDHVEIDESELRIDVYRSSGPGGQGVNTTDSAVRITHLPTGIVVSCQNERSQIQ
                     NKATAMNVLQAKLLERRRQEEQAKMDALKGDGGNSWGNQMRSYVLHPYQMVKDLRTEFE
                     VGNPEAVFNGEIDGFLEAGIRWRKQQEK"
     gene            complement(18390..19622)
                     /locus_tag="GQF42_RS18510"
                     /old_locus_tag="GQF42_18510"
     CDS             complement(18390..19622)
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014673043.1"
                     /locus_tag="GQF42_RS18510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_18510"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_158921341.1"
                     /sec_met_domain="Pkinase (E-value: 7.4e-48, bitscore:
                     162.2, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARKIGSRYTANQILGRGSAGTVWLGEGPDGPVAVKMLREDLASD
                     QELVGRFVQERTALLGLEHPHIVTVRDLVVDGNDLALVMDLVRGTDLRTRLERERRLAP
                     EAAVAIAADIADALAAAHAAGVVHRDVKPENVLLDMQGPLGPGGAHPALLTDFGVAKLI
                     DSPRRTRATKIIGTPDYLAPEIVEGLPPRASVDIYALATVLYELLAGFTPFGGGHPGAV
                     LRRHVTETVVPLPGIPEELWQLLVQCLAKAPASRLRASELAARLREQLPMLVGMPPLDV
                     DEPDQSEEPAAQEQAPSAPAGDEPVRRRGAVSLVPGAKPDSNRDTHTSMRVPGPDELAG
                     GAHGTARAPRATGAPRPGSARHRAAMRRRRITLGVAGVVVAAVVGVGAWLASSGGGDQQ
                     PAQDTHSTSAP"
ORIGIN
        1 atcagggagc cgagcagggg gccgatgaag gtgaggtagg ccgcctggag cggggtgcgg
       61 ccgaactggt tcgtcaggac ctggccgaag gcgaagctgt agccgatgaa ggagccgaag
      121 gtaccgacgt agaggaacga catgatccag gtgtgggcgt ccttggccgc gtccttcgcc
      181 gcgccggtgt cgttcttcac cgtcgccagg ttgtccatga agatcgccgc cgccacggcc
      241 gccacgacga tcagcgggat gtagatgccc agcagcacgc gcgggccgcc gttcgcgccg
      301 atgatcgcga gtgcgacgag ctggatgacc ggcacgccca cgttcccgcc gccggcgttc
      361 agccccagcg cccagccctt cctcttcagc gggaagaagg cgttgatgtt ggtcatggag
      421 gaggcgaagt tgccgccgcc gatgccggcc agcaggccga ccagcaggaa cgtggtgaag
      481 gacgtgcccg gccgcatcac cgcgaacgcc gccaccgtcg gcaccagcag caggctcgcc
      541 gagatgatcg tccagttgcg gccgccgaag accgccacgg cgaaggtgta cgggacgcgg
      601 acgaccgcgc cgaccagcgt gaccatcgag gtcagcagga acttgtccgc gggcgtgagg
      661 ccgtactgcg gacccatgaa caggacgagg acggaccaga gggtccagac cgagaagccg
      721 acgtgttccg agagcaccga gaaccacagg ttccggcggg cgatccgctc cccgctcgct
      781 cgccagaacc cctcgtcctc cgggtcccac cgctcgatcc agcggccact gcgacggggt
      841 agggctgggg ctgtcatcgc tcctccacgg tgctccggct gctcgttctg tcatacggcg
      901 gtccgctgta cgactggctg aacccgaagg tagggagcac gcgtttccgc gctgtggccg
      961 tgggtgaccg gaagggaacg ttgctctcac gcggccggtg accggtccgt gagggcgcgc
     1021 agccggtgtc tcaggacgcg atccggtagc ggtgctcggg gcggccggtc gccccgtagc
     1081 gcaggatcag gcggaccatt ccctccttga cgaggtacga gaggtagcgc tgggccgtgg
     1141 cccgggagac gccggtcagc tcggcggcct cggcggccga caggtcgcgg tgagcggtgc
     1201 gcagcgtctg ctggacgagg gcgagcgtcg gcgccgagtg gcccttggcc gggacccggg
     1261 gcacggcggg cggccggacc gcgctgaaca gggcgtccac atcggcctgt tcggtctccg
     1321 tggtctcccc gagggtgtcg acgcggtgct ggagttcgcg gtacgaggtg agccgctcgg
     1381 ccaggtcggc ggcgccgaac ggcttgacca ggtagcccac ggcgccgagt ttcatggcgg
     1441 tgcggacgga ggcgatgtca cggtccgcgg tgatcacgaa ggcgtcgggg cgggcgcccc
     1501 ccgcgtcccc ggtgaggcgg cgcagcacgt ccagtccgct gccgtcgggc aggaagatgt
     1561 cgaggaggag caggtcgggg cgcaggtcgt gcgccgcctc cagcgcctcg gccacggtcg
     1621 ccgcctcgcc caccacctcg tagccccgca cccgggacac gtagtcgcag tggatgtggc
     1681 tgacccggaa gtcgtcgtcc acgaccagcg tgcggatcat cggcggtcac ctcccacggg
     1741 cagcgcctcg gcgaatctgt tcttcggccg cacggcgggg gccggcagtc gtacggtgaa
     1801 gaccgcgccc gggccctcgc tgacggtgat cgtgccgccg tgccgcgaca ccaggcggtg
     1861 gaccagggcg aggcccaggc cgcggcgggc ggtgccccgg tcggggcggg tcgaccagcc
     1921 atcctcgaag atcgactcgc gggcgccggg cgggatgccg gggccggtgt ccgccacccg
     1981 taccgtcgtg ccccgctcgt cctcggtgag ggcgaggcgg accgtgcgcc cgtccgccgg
     2041 gggcggtccg tcgcccgccg cgtcgatcgc gttgtccagc aggttgccga cgatcgtcag
     2101 cagcaggcgc agctgcggcg ggtccgcgcc gagcgccgag tcgtcggcca gctcgaccca
     2161 cacaccgcgt tcggcggcca ccgtggtctt ggccacgacc aggccgacca tcagtgggtt
     2221 gccgatccgc ccccgcacga actcggtgag cgcctgcccg gcgccggccg actccacggc
     2281 caggtcgtac gcgtcgtcgt acgccccgat gtccagaagc ccggcgagcg tgtgcatccg
     2341 gttggtgaac tcgtgctgct gggcgcgcag ggcgtccgtc agaccgcgta cggagtccag
     2401 ctcccgcagc agcccgacca gttcggtgcg gtcgcggacg gtcaccaccg cgcccagcgc
     2461 gcggccgtgc agggtcaccg gcatccggtt gacgaccaga cagtgctcgt ccgtcaggac
     2521 gctgatgtcg gtgccggtca gggtgccgtc cagggcgcgg cgcagccgtc cgtcgggcag
     2581 cacctcgtcc agggtgctgc cgagggcggt gccgaggccg atcagccgcc gggcctcgtc
     2641 gttgaccacg ctgatccggc cgtccggggc gaaggcgagc acgccctcgc ggatgccgtg
     2701 cagcatcgcc tcgcggtcct gcagcagccc ggcgatctcc tccagctcca gcccgaacgt
     2761 ggtccgcttc agccgcctgg ccagcagaaa cgcggccgcg gccccgagcg cggtggcgat
     2821 cgcggcgtac acggcgaagg tgagcagctc gtgccacagc tcgcccagta cgtcgcgctc
     2881 cgggatgccc accgacacct cgccgaccag ctcgcccgtc ggcccgtaca gcgggaccct
     2941 gccgttggcg gaccgcccgg tcgcgccctg gtcggtgccg acgtgcggct gcccgtcccg
     3001 cgccacgatc ggctcggcca ccggcgagcc gaccagttgc ggcatggggt gcgagtggcg
     3061 gaccccgtgc aggtcgatga ccacgacgta cgacgccccc gacgactgcc ggatgcgttc
     3121 ggcgacggcc tggacgacgg cgccgccgcc gtcctgcatg gcccgccgga tctgcggatc
     3181 ggcggccgtc gtcttggcga tggccacggc ccgctcctcg taggtgcggt cgagggcgga
     3241 gcgctgcgcg aaggcgaaca gggcgaagcc gatgacgccc gtgagcgcca ggatggcgag
     3301 ctggctgacg aggatccgcg cggacagtct ccccctcccg ccgcgcccga tccgtatgcg
     3361 gatgggtgtc acaggtgcct catcgcccct gttccgtttg gtgccgggcc ggccctgcgc
     3421 cggacccgtg gtggcgtgat tgtgcctgat ggccggaatt ctgcccagcc ccgtttcact
     3481 gagcagaacg agcagaactc ctggttacgc ggctatcgcg ggatacctgt gaaacagcga
     3541 cgtaacacgg ggtggcctct agcgtctgcc ttcacctcga cccccgaggg gaaaggagac
     3601 cgctccccat ggcttccagc agtgccggtg cggcggtgcg cgaggacgcg cacatcgaga
     3661 tatccgggct caccaagcga ttcctgacgc ctgccggtga ggtgttcacg gcgctggagg
     3721 gcgtgtcgtt caccgtggag cccggccagt tctgcgcggt ggtcggcccc accggctgcg
     3781 gcaagtcgac caccctgggc atggtgtccg gcctcgaccg gcccagcgag ggctcggtca
     3841 aggtcggcgg ccgcgaggtg gacggcatca ccgacggcgt cagcttcatg ttccaggcgg
     3901 acgcgctgct gccctggaag agcgtcctcg gcaacgtgct gatggggccg gtcttccggg
     3961 gggtgcccaa gcagcaggcg cagaccgccg cccgggactg gctgcgccgg gtcggactgt
     4021 ccgggttcga ggaccgttac ccccaccagc tctccggcgg tatgcgcaag cgcgtggcca
     4081 tggccgcggc gctgatcaac gaacccaaga tcctgatcat ggacgagccg ttcggcgcgc
     4141 tggacgtgca gaccaaggcg atcatgtcga ccgagctgct gggcctctgg gagcagatcc
     4201 ggccgtccgt catcttcatc acccacgacc tcgacgaggc cgtggcgctc gccgaccggg
     4261 tcgtcgtgat gacctccagc cccggttcgg tcaaggcggt cttcgacatc gacctgccgc
     4321 gcccgcgcgg ctccgtccag gagatccgct tccagccccg cttcatcgaa ctccagcaac
     4381 agatctggga aacgctgcgc gaagaggtcg agcgcgccta cgcacgcacc gcaggaggca
     4441 aggcatgagc acgacgtcca ccgcttccgc cgcgcaggtc gcgggcggca agcagtcctc
     4501 cgcggcggca gccgccaagc aggccgcccg gcggcgggtc gcgtcggtct gggcgggccg
     4561 catcggcatc gcggtcttcg tcatcggcgg ctggcaggcc ttcaccacgt ggggcatcgt
     4621 cgacccgttc ttcttcggac agccttccgg catctggaag cggctggtcg acctcttcca
     4681 gcacggcacc gagttcggct ccttctacgc gaacatctgg accaccatcc aggaagcgct
     4741 catcgggttc gccgtcggcg ccgtcgccgg agtcgtcttc ggcgtggccc tcggccagag
     4801 ccgctacctg tccgacgtcc tcgggcccta catcaagatg gtcaacgcga tcccgcgcat
     4861 cgtcctcggc tcgatcttca tcgtcgcgtt cggcatcggc gtgaccccta agatcctgct
     4921 cgccgccgtg ctggtgttct tcatcgtctt cttcaacgcc ttccagggcg tccgcgaggt
     4981 cgaccgcaac atcctggcca acgcccgggt cctcggcgcc tcccagctgc agatcgtccg
     5041 gcacgtcatc gtgccctccg cgctcacctg gatcatcgcc agcctgcaca gcgccttcgg
     5101 cttcgccatc gtcggcgcgc tggtcggcga ggtgctcggc gcgcagagcg gcctcggtct
     5161 cgtcatcaag accgcgcaga acaacttcga ccccaacggc gtgttcgcca cgatgctcgt
     5221 catctcggtc atcgtgctgg gcgcggagtg gctgatcgcc aagctcgaac accggctgct
     5281 gtcctggcgc ccgccggccc ccaccgaggc gaactccctc tgaccgcccc tgacttaccc
     5341 ctccctgccc ccttcccctc cctccccgcg tcccctcgca ggtccgaaag gtacgagccg
     5401 ccatgctgaa aagagccctc accgcatcca tcgtcaccgc cctcaccctc ggcgcggcca
     5461 ccgcgtgttc cggcagctcc ggcggctcgt cggcctccgg cggcaccccg accgtcaaga
     5521 tcatggtcgg cggcatcgac aagcagatct acctgccgta ccagctcgcc gacaacctcg
     5581 gcttctacaa gaagtacggc gtcaacgtcg tcctgagcac cgagcaggac ggcggcaccg
     5641 gcgccgagga cgccatggcc tccgggcagg tggacatggc cggagcctgg tacaaccaca
     5701 cgatcgactt ccaggcgaag ggcaaggcgg tcgaggacgt catccagctg tccggtgcgc
     5761 ccggcgagcg ggagatgtgc accccgaaga gcggcgtcca ctcggccgcc gacttcaagg
     5821 gcaagacgct gggcgtcacc gacctgggtt cgggcaccga caccctcacc aagttcctgg
     5881 ccgccaagaa gggcctcaag accggcgact tcagccggat cggggtcggc gcgggctcca
     5941 ccgccgtcgc agcgctccag aacggcaaga ccgcctgcgt catgacgaca cagccgacgg
     6001 tcgccgcgat ggagaagaag ggcgtcggca cctccgcgat cgacctggcc accacccagg
     6061 gcgccaccgc cgcgctgggc agcgcctggc cggccgccag cgtcatcgcc cgtaccgact
     6121 gggtgaactc gcacaaggac gcggtgcaga aggtcgtcga cgcgctcgtg gccaccatgc
     6181 actggatcaa cacgcacagc gcggccgaca tcgccgacaa gctgccgcag tcgttcgtgc
     6241 agaaccagct ggtcaccaag gccgactacg tcacggccct gaaccaggac aaggggcagt
     6301 tcctcccgga cggcctgatg ccggccggcg gcccgaagac cgtcctggcc accgaggaac
     6361 tggtcggcaa cgccacctcc tcgatcgacc tgagcaagac gttcaccaac gacttcgtgc
     6421 tccaggccaa caagctggag ggcctgaaga ccacgacgac cccggcgggc gcgaacggct
     6481 gatcctcaac cggctgacgg ggccacctgg tcggagacga cccggtggcc ccgtcagccg
     6541 gtcgccgtca tctcgtccgc cgccgggagc cagctcccct ccggccggcg cagccacccc
     6601 tgcgccgccg cgatccgcgc cgccgcgccg cgcagcgcgt ccagccccgg atggaccagg
     6661 cccctgcgcc acaccagcga gaccggcgac agcggaacgg ggtcgacgag cgggcggcgg
     6721 accgtgcggg gcagggccgg gaagtccacc acggccagca ccggataccg ggtcttgccc
     6781 atgatccgct cgaactcctc gtccccgacg gccagcggca gcggcggggc gagccggatg
     6841 ccgtactgcg cgaagagccg ggacgccagg tcggtccact ccagggtgcg cggattgccg
     6901 gcaccggcgt acaccgtctc cccggtcatc ccggccaccg gtatctccgg cagcgcggcc
     6961 agggggtgtt cctcgggcag gaccacggcc atcggctcgt agcgcaccgg ctgccgctcc
     7021 agccctgacc gcagcgccgg gtccagcccg gcgaaccggc cgaaggagac gtccagccgg
     7081 cccgacagga tctgctcggc ggctccggtc agaccgctct cgtagcgggc catcagctcg
     7141 cagtcggggg cgagttcacg ggcccggtgc agcacccggc gaccggtgac gaggcccggc
     7201 gagttgaggt ccaccagcag cgggcgggcc tgcccgaagg acgtgcaggc cgccagcagc
     7261 tcgtcctggg ccgccaggac ccgtcgggcg tacggcagca ggcgctcgcc gtcggccgtc
     7321 agcgtcacct gccgcgtgct ccgcaggaac agctcggcgc ccaactcccg ctccagccgc
     7381 cgtacatcac ggctgagcgc ctgctgggcg acgtacagcc gggcggcggc ccgggtgaag
     7441 tgcagttcct cggcgacggc gacgaaggcg cgcagcagtc tcgggtccag gtcggcgggc
     7501 atgagcgcga acctacaaca caggtgcgtg aatgggcgcc gagcaggtgt tggacccctt
     7561 gatccgccct gggcgagggt gcgtccatgc cctccgtcat atccacgccg acgcgccgga
     7621 gcgcctacct ccggctcttc tccctccccg gtacgcgcgc gttcaccacc ggcaatctgc
     7681 tcgcccggct gccgatgggc atgttcagcg tgagcgccgt cgtgatgatc gccggttccc
     7741 ggggctcgta cgccctcgcc ggtgccgtca ccgcgaccgg actcgccgcg accgggctgg
     7801 ccgggccctg gatcgcccgg ctgatcgacc ggcacggaca ggcccggatc gccgtgcccg
     7861 ccacgcttct ctccgtgctc ggcagcctcg cgctgctgct gtgcgtgcgc ttcggcgctc
     7921 ccgactggac cctgttcgcc gcctacgccg cgaccgcggc cacccccaac atcggcggac
     7981 tctcccgcgc ccgctgggcc catctgctgc gcgacgactc cggcgcgctg cacaccgcga
     8041 acgccttcga gcaggccgcc gacgagctgt gcttcatgct cggcccggtg ctcgcgtcct
     8101 tcctgaccgg cacgttcttc ccggaggcgg gcacgctcac cggggcggtg ctgctgctcg
     8161 ccggcatgct gctgttcacc gcgcagcgcg ccaccgagcc gccggtcggc gcccgttcga
     8221 aggcgccgtc gccgctgcgc agccccggca tccggccgct gctggcctgc ttcgtcgcga
     8281 ccggcatggt gttcggctcg atggaggtcg gcacgatcgc cttcgccgac gcgcacggcc
     8341 accgcgcggt ggccggtgcc gtcctcgcac tccaggcggc gggctcgtgc gcggcgggcc
     8401 tggtgttcgg ggcgcgcagg ccggcggggg tgcggctcgg ccactgcctg gccgccatgg
     8461 ccgtcctgat gaccctgccg tgggcggcgg ccggggcggc cggctcgctg ccggggctcg
     8521 cgggcgcgct gctggtcgcg ggcatggcga ccgcgccgac gatggtgacg gcgatgaccc
     8581 tggtgcagcg gcgcaccccg gccgaccggc tgaacgaggg catgagcctg gtggtgaccg
     8641 ggctgctcac cggcatcgcc tgcggctcgg cggccggcgg ctggacggcc cagcacctct
     8701 cccccggcac cgccctcgcc gtcccggcca ccgcggccgc gctcgcgctg ctcgtccaca
     8761 cggcatcgac gggcgcccgg cggaacgtca gcgcagacgg accggaagac tgagcaggcc
     8821 gcggtgccga gggttgtcct gccactcggg ggcacgctcg cgaccggcga gacgcaggcc
     8881 ggggaagcgt cgcagtacgt gggtgaaagc gatctcggcc tgcagccggg ccagcggtgc
     8941 gcccaggcag tgatggatgc cgtggccgaa cgccaggtgc cgggaggcgt cgcgggtgac
     9001 gtcgaagcgg tcggggtccg cgaagaccgc cgggtcccgg ttggcggccg ccaacgcgat
     9061 ctgcacgaac tccccggccg ggatcgtcgt accggcgatc gtcaccggct cggtggtgta
     9121 gcgcaggctc gcgagcgcga acgggctctc gtggcgcagg acttcctcgg tcaggccggg
     9181 gacgagcgcg ggatcggcgc gtacggcggc gagctgcccg ggatgcgtga gcagcgcgta
     9241 caggccgttg gcgacgagat tgaccgtggt ctggtggccc gcgatcacca gcaggaacgc
     9301 catcgaggtg acctcctgcc cggtgaggcg ctcgccgtcg gcgcgggcgg cgaggagagc
     9361 ggagagcagg tcgtcgccgg ggtgggcgcg cttgtcctcg accagctccc gcagccgctc
     9421 cagcatggtc tcggcggtcg ggacggacac ctccccgtct cccccgtccc cgcccaccgt
     9481 gtggcccctg acctggagga tcccgtgcgc gccggggtcc gcgccgagca gctcgaagat
     9541 caccgcgagc ggcagcggca gcgcgaaccg ggcgatcagg tcgacctcgc ccgcctcgtc
     9601 cgcccggtcc accgcgtcga ggagtgcggt gacgtgggcc tcgatccggg ggcgcagctc
     9661 cgccacccgc cgctgggtga acgcctgttg caccagccgg cgcaggcgcg tgtggcgcgg
     9721 cgggtcggag ttgagcatgt gcgtggtgag cgctccgccc ggaccgccgc ccggcaggcc
     9781 ctcgtggcgg gcgtacgcct cagtcgcgcc gtccttgctc agccgggggt cggcgagcgc
     9841 cgcccggcag gcggcgtgcc cggtgacgac ccagccggcc aagggggcgg cgccggagaa
     9901 acggaccttg cgcaccccgc cctcctcgcg ccagcgccgg tagacgtcgt gcgggcgacc
     9961 ggcgaaggac tcgtccaccg tctccgtgtc gtacgacatc tcaggcagcg gcacggcgca
    10021 ccttcgtcac ctgtacgtcc tccacgccga gcagtccgac gagcgggacc ttggcggagc
    10081 gctggtcggg gctgaccgcg aggccggacc cgcggatcag gtccaggagc agttcggcga
    10141 gcggcatcac catgtgccgg ccccagcagc gctcggagga gtggccgaag gggaggtagc
    10201 cgggggcggt gtcgggatcg aggctctccc agcgctccgg gcggaactcg tgcgggtcct
    10261 cccacagctt ggggtcccgg tgcgtcagga ggggcaggag caggacgtcg tcacccgcgc
    10321 cgatgcggtc gtcgacggcg gggtactcgg gggaggcgtt gcgcaggatg ttccaggacg
    10381 gcggcagcag ccgcatggac tcgtggagga tgtgccggtt cggggtgtcg gggtcgaacg
    10441 gcgagccgag ccagagcgcg ttcgcgacca gggtggagac cgtgaagcac accggggccg
    10501 ccgcgcgccg gtacatgccc atggcgtacc ggcgctcgtg gtagccgccg gcgtcggccg
    10561 tcagccccgc gatcgcggtc agcggggcgc cgcgccgccc gacccgcccc gggagcgcgg
    10621 cgcccgccgc gatcaccgcc caggtgagct tgggggtcag ttcgaggttg cggctcatca
    10681 ggatccgcag ccggtagggg tccttgccga ggatcaggtc ccgcaggaac agatgccccc
    10741 tgagcggcca gaccccggac aggtcgacgt cctcgggccc ggggcgggac ctcttcagcg
    10801 cctcgcgtac gtcgccgccg atggtccgca tcaccgagga ggcctcgccg cgtgagatcg
    10861 accgtccgtg cagtggcttg aacgtgggcc gctcggtctc ggtggcccgg cgggcggcga
    10921 ggatccggtc ggcgacctcg tacccggcga tgccgacggt gtcgggttcg agccggaaga
    10981 cgtcctgccc gagatggtcc cggaacaggg cggcaagccg tgggtggaac aacgtgcggc
    11041 gcatgcgggt ctccggaaga ccgagggggc ggacgtcggc gggcggcgtc gcccccgccg
    11101 ggcagcgggg gcgaccactc ggcttcggct tagtaccaga agtaccaggc gctcgccttc
    11161 aggctcttct gagcggacac cttgttacgg atggcgaaga gaagcttcat cactacaccc
    11221 cctttccggg tggagctgtc acgcgcttcc tcttgtggag gtcgtgcgca gatggcttca
    11281 caaggctccg acgcggggat caacaaatga tgaacgcgca gctcagggca tgtccgggca
    11341 tgacaaaggc cccgccgctc gcagcgacgg ggcctgtgcc cacatgggat gagtggagat
    11401 ggcgggaatc gaacccgcgt ccaacggtgc ggaatcaggg cttctccgtg tgcagttcgc
    11461 tgtgattttc tcagccccgg cgatcacgcg aacaagtcgc cgacgggctc agtcactgtt
    11521 tggtttccct cttcaccccg tgaccgggat caaggtttag ttccctagct gatgccagga
    11581 tccgggtcgg gaacagcccc gggctgacac ttcgcaagtc gctacttagg cagcgagggc
    11641 gaaggaatcg cgcttggtgt tggcgattat tttttgcgac atatggttta cgagatcatt
    11701 gccgcttcct cgacacgctt cccctgcttc gacagccgct gtcgaaaccg atcatcccca
    11761 tgttgccact cttgaattaa atacagctca acgcacacac cgggttcatc cggtgttggc
    11821 gccatcgtac gtgaccaacc cacgccgatg ccaccgtatt ccctggctac acgccgcgct
    11881 gcctgcgctt cgccgccgcg atcgcgcggt ccgactcgcg ccggtcctgc ttctcccgca
    11941 gggtctggcg cttgtcgtac tccttcttgc cgcgcgcgag agcgatctcg gccttcgccc
    12001 ggccgtcctt gaagtagatg gcgaggggca cgatcgtgtg cccggtctcc tgggacttcg
    12061 actccagctt gtcgatctcc tcgcggtgca ggagcagctt gcgcttgcgg cgcgcggagt
    12121 ggttggtcca gctgccctgg tggtactcgg ggatgtgggc gttgtgcagc cacgcctcac
    12181 cgcggtcgat ctggacgaag ccgtcggtca gcgaggtccg tccctcgcgc agcgacttga
    12241 cctcggtgcc catgagtacg agcccggcct cgtaggtgtc gatgatcgcg tagtcgtgcc
    12301 gggccttctt gttctgggcg acgatcttgc gcttgccgcc cttctcgccg tccctggcct
    12361 tggcggcccc gccgccctgc ttgggctggg actccttggg tacgtacatt cccttgctca
    12421 tagtgccgtc cattttcgca ctacacaggg gtccggcggc cagcctttaa tcggcgtcgc
    12481 ccaggccgcc gagcacggtc tcggcccgct ccacggcggc ctgcccgtcg gcctgcccga
    12541 catccaggtc gggggtgata ccgcgaccgt cgacgctgtg gcccaagggg gtgcggtagt
    12601 gcccgacggt cagttcggcg acggatccgc cgggcagccg agtcggcatc tggatggagc
    12661 ccttgccgaa ggtgcgggag ccgatcacca ccgcgcggcc ccggtcctgc agggcgccgg
    12721 tgagcatctc ggcggcgctc atcgtgccgc cgtcgaccag ggcgaccagc ggccgggcgg
    12781 tggcgccgcc ggggtcggcg tgcagggagc gctgggcgcc gtcgacgtcg taggtggcga
    12841 ccaggccgcc gtcgaggaag gcggaggagg tctcgaccgc ctcggtgacc aggccgccgg
    12901 agttgccccg caggtcgagg atgatcccgg cgtcggccgg ggcctggcgc accgcggcgc
    12961 ggacggcgtc gccggatccc ttggtgaacg cggcgatctt gatgaccgtg accccgccgg
    13021 gcagcctgct cacgctcacc gagtcggtgg acaggctggc ccggcgcagt ttctcgctcc
    13081 acgcgcgcgt gccgcgctcc aggcccagcg tgacggtcgt cccggcggcc gcgtcgtcgg
    13141 cgtcgccgcg cagtaacgcg accacgtcgg tgaccgggcg gccgtcgacc ttgctgccgt
    13201 cgacactggt gagccggtcg cccttgcgga tgccggcccg gtcggcgggc gagccgggct
    13261 ggaccctggt cacctcgatc cggccgtcct gctcgcggcg tgcccacagc cccacgccgg
    13321 tgtacttgcc gtcgagggct tcctggaact cctggtactc gccctcggag tagacggctc
    13381 cccagcggtc gccgctgcgg ctgacggccc gctcggcggc ctccatcggg gacttcccgt
    13441 cggccgcggc ctcggcggcg gccttctgga cgtcctcgtg cggggtggtg gccgtggccg
    13501 ccgggccgaa cgcgggcttg cggttgggct ggccggcctc cgggaaggag ccggtggcgg
    13561 caccggcgac caggacgccg gcgaagacca atgtcagggt ggccccgcgg cggatgcggc
    13621 ggggcgggca gaacaggtct cggcctgaca tggccgtgag tctaggacaa cgcgaagggc
    13681 cgtacgggcg gttgcccgta cggccctctt ggcatgcgtc acaccttcag gtacttgcgc
    13741 agcgcgaaga acgccgccaa ggacggcatc agcacgctcg tcgcgaggat cagcggcagc
    13801 ttggccaaca ccgcgtccca gcccacgaag ttgatgagct ggagcttgtg ggcgaggtcc
    13861 atgccgtggt cgatggtgaa gtaccggccg accagcaggg ccacgcaggc cagtccgccg
    13921 ccgatgagtc cggcgaccgc ggcctccgcg atgaacggcg cctggatgta gaagcccgag
    13981 gcaccgacca ggcgcatgat cccggtctcg cgccggcggc tgaacgccga gacgcgcacc
    14041 gtgttgacga tcagcagcag cgcgacgatc agcatcatcg ccatcacgcc gagcgcgccg
    14101 cggttcatca ggttcagcag ctggaagagg ttgtccagga tgcccttctg gtcctgcacc
    14161 gactgcacgc cgtcacgccc gttgaaggcg ctcgcgacga cctggtactt ctgcgggtcc
    14221 ttgagcttga tccggtacga ctcctgcatc tggtccggcg tcagcgagct ggccagcggg
    14281 gagttgccga actgcgcctt gtagtgcttg taggcatcgt cctgcgactc gtacgagacc
    14341 ttctcgacga tcggcatgtt gtgcaggtcg gcgaggatct gcttcttctg gtcctcggtg
    14401 accgcgccct tggcgcagtt gacgtccgac tcggcatcgt gcttgttgca caggaagatc
    14461 gagacgttga ccttgtcgta ccagtagccc ttcatggtgg acacctggtc gctcatcagc
    14521 agcgagccgc cgaaaagagc caaggacagg gcgacagaga cgatgacggc gaaggtcatc
    14581 gtcagattgc ggcggagacc gactccgatc tccgacagga cgaactgggc gcgcatggcg
    14641 tcgggtcaag cctttccgtc gtgaacttgc ttagtgctgg tagccgtaga cgccgcgggc
    14701 ctggtcgcgg acgaggcggc ccttctccag ctcgatgacg cgcttgcgca tctggtccac
    14761 gatgttctgg tcgtgcgtcg ccatgatgac ggtggtgccc gtccggttga tgcggtcgag
    14821 cagcttcatg atgccgacgg aggtctgcgg gtcgaggttg ccggtgggtt cgtcggcgat
    14881 gagcagcttg ggccggttga cgaaggcccg cgcgatggcc acgcgctgct gctcgccacc
    14941 ggacagttcg ccgggcatac ggtcctcctt gccgccgagc ccgacgaggt cgagcacctg
    15001 cggcaccgac ttgcggatct cgccgcggga cttgccgatg acctcctggg cgaaggccac
    15061 gttctccgcg acggtcttgt tcggcaggag ccggaagtcc tggaagacgg tccccagctg
    15121 gcggcgcatc tgcggcacct tccagttgga gaggcgggcg aggtccttgc ccagcacgtg
    15181 cacctggccg tggctgcacc gctcctcacg gaggatgagc cgcaggaagg tggactttcc
    15241 ggagccggag gaccccacga ggaagacgaa ctcgcccttc tccagctcca gggagacatc
    15301 cctgagcgcg gggcgggtct gcttggggta gaccttggag acgttgtcga atcggatcac
    15361 ggatgcacca cgggtcgccg ggggtagatg agcgtgacca tacgcgaacc gggtgtgcaa
    15421 gtgcagtcgc aggtagagct tgggcaagac ttgtacgttt ttgtaccggc ccctgtttcc
    15481 gttcggctct cccgggggcc cgcgcacggc ttgcgggaac ctggcacagt ggagtgggga
    15541 acgttctcgt tccccagagc gttttcgtag tgatggccgg tgcaaggagg gcgagcgcat
    15601 gacgtacgac cggttggtgt gcgcgaactg tgcggcgccc gtgagcgagg gccggtgccc
    15661 ggtgtgccgc gccaaccgcg agcgactgca gcaagagggc tttctgggcg gggtgaaccc
    15721 gatggcgctg atcgcgctgc tggcggtgct gatcgccgcg gtggcgctgc tggcgcacca
    15781 gaccgcctga gccgcggcgg aaggtgccgt cgagacggcg aagggcccgg agcgccaagc
    15841 tccgggccct tgcgcatgcg gggtgcgtgc gctgcgtgac cgtagggcta cggtcaggcc
    15901 gcggcgccgc cccggccgtt catcaggcgc ggcagcacac ggaagccgat gccgccggcg
    15961 atcatcgtcg cggcgccgat gagcaggaac tcggtcgggc cggcaccggt ctcggcgagc
    16021 tgcttgtcgc caccctgggc ctgggccttg ttgccggagc ccgtgtcggt cagcgtcgag
    16081 gagcccgcgt cctgggtggc cttgccgctg ccgccctgcg ggttgtcgtt gttgccgccg
    16141 gtgctgccgg agccgcccga ggtgctggag ccgccggtgg agctgccgcc ggtggtgctg
    16201 gaaccgccgg tggtggagcc gccggtggtc gagccaccat tggtggagcc gccggtggtg
    16261 gtgccaccgg tggtcgagcc accggtggtc gagccaccgg tggtcgagcc gccggtggtg
    16321 gtgccgccgg tggtggtgcc gccggtggtc gagccaccgt ccgcggtgcc gccggtggtc
    16381 gagccaccgt ccgcggtgcc gccggtggtc gagccaccgt ccgcggtgcc gccggtggtc
    16441 gagccaccgt ccgcggtgcc gccggtggtc gagccaccgt ccgtggtgcc accattggtc
    16501 gagccaccgt ccgtggtgcc accattggtc gagccaccgt ccgtggtgcc accattggtc
    16561 gagccaccgt ccgtggtgcc gccggtggtg gagccaccgt tggtcgagcc accgtcggtg
    16621 ctgccaccgt ccgtggtgcc gccgatgctg acagtgccac cgaccgtggt cccaccgtcc
    16681 gtggtcccac cgttggtcga gccgccgttg gtgccgccat cggtggtgcc gccgtcggtg
    16741 cagacggcga ccgggcagcc gccgccatcg gtgccgccgt cgtcgttccc ggcgtccgtg
    16801 tgcacgccca ggctgatcgg tccggcctgg acatcgatgc ccgcggcgga ggccgcgccg
    16861 gctgcggtca gtgacgcacc ggccgcgatc acggcgcccg cggctatccg cgcgacccgg
    16921 atccgcgtct tcttcgtcat atggttgcta cccccagtag ctgttcgtca atgaggcggc
    16981 gcgtggggca ttagccgtga tcgacggggg gcagccggtg acgaagcgcg tcaactcatt
    17041 cccccggttc acatgcgccc cgcaagtacg catgccgcgg gcaactcttc ccattcttca
    17101 aagcaacgtc aaggccgttg cgggcgcgat gtcctttgaa tgggcgtttg tgatgagttg
    17161 aagcctgtaa ttgtgatgta aaacccagac ataacaacaa ctgccgcctc tcgggcggca
    17221 gttgtcatgt cgacaaagtt acttctcctg ctgcttgcgc cagcgaattc cggcctcgag
    17281 gaacccgtcg atctcgccgt tgaacacggc ctccgggttg ccgacctcga actcggtgcg
    17341 caggtccttg accatctggt acgggtgcag gacgtacgaa cgcatctggt tgccccagga
    17401 gttgccgccg tcgcccttga gggcgtccat cttggcctgc tcctcctggc ggcgccgctc
    17461 gagcagcttg gcctggagga cgttcatcgc cgtggccttg ttctggatct gcgagcgctc
    17521 gttctgacag gagaccacga tgccggtcgg caggtgcgtg atgcggaccg cggagtcggt
    17581 cgtgttgaca ccctggccac cggggcccga ggagcggtag acgtcgatgc gcagctcgga
    17641 ctcgtcgatc tcgacgtggt cggactgctc gaccacgggc agcacctcga cgcccgcgaa
    17701 ggacgtctga cggcggccct ggttgtcgta gggcgagatg cgcacgaggc ggtgcgtgcc
    17761 ctgctcgacg gagagggtgc cgtaggcgta cggcgcctgc acggagaagg tggtcgactt
    17821 gatgccggcc tcctcggcgt acgacgtctc gatcagctcg gtcttgtagc cacgctgctc
    17881 ggcccagcgc aggtacatgc gctggagctt ctcggcgaag tcggcggcgt cgacaccgcc
    17941 ggcctcggcg cggatgttga ccagcgcctc acgcgagtcg tactcgccgg acaggagggt
    18001 gcgcacctcc atctcgtcca gcgacttgcg caccgcggcc agctcggact cggcctcggc
    18061 acgggtgtcc gggtcgtcct cctcctcggc catctcgaag aggacggcga ggtcgtcgat
    18121 ccggccgcga agcgcctccg ccttccggac ctcggcctgg aggtgggaga gcttgctcgt
    18181 gatcttctgc gcctcgtccg ggttgtccca cagggacggc gcggccgcct gctcctcgag
    18241 cacggcgaca tctgccctca tcctgtcgag gtccaggacg gcctcgatcg actccatggt
    18301 cgaggagagg gacttcagct cttcggatac atcgacgact gccacgcctc cagcgtaacg
    18361 gctgtggcaa ggaacccggg cagggcgtct cagggcgccg acgtgctgtg ggtgtcctgc
    18421 gccggctgct ggtcgccccc gcccgaggag gccagccacg cgccgacgcc caccacggcc
    18481 gccacgacca cccctgccac gcccagtgtg atccggcgcc gccgcatcgc cgcccggtgc
    18541 cgggccgagc ccggccgggg cgcaccggtg gcccggggag cgcgagcggt cccatgggcg
    18601 ccccccgcca gctcgtccgg ccccggcacc cgcatcgagg tgtgcgtgtc ccggttggag
    18661 tccggcttgg cgcccggcac cagcgacacc gctccccgcc gccgtaccgg ctcgtcgccg
    18721 gccggagccg acggggcctg ctcctgggcc gcgggctcct cgctctggtc cggctcgtcc
    18781 acgtccagcg ggggcattcc gaccagcatc ggcagctgct cgcgcagccg cgccgccagc
    18841 tccgaggccc gcagccggga ggcgggcgcc ttggccagac actgcacgag cagctgccac
    18901 agctcctccg ggataccggg cagcggtacg acggtctcgg tgacgtgccg gcgcaggacc
    18961 gcgccggggt ggccgccgcc gaagggggtg aagccggcca gcagctcgta cagcacggtc
    19021 gcgagggcgt agatgtcgac ggacgcgcgc ggcggcaggc cctcgacgat ctccggggcc
    19081 aggtagtccg gagtgccgat gatcttcgtg gcgcgggtcc gcctgggcga gtcgatcagc
    19141 ttggcgacgc cgaagtcggt gagcagcgcc gggtgggcgc cgccggggcc gagcgggccc
    19201 tgcatgtcca gcagtacgtt ctcgggcttg acgtcccggt ggacgacccc ggccgcgtgg
    19261 gccgccgcga gcgcgtcggc gatgtcggcg gcgatcgcca cggccgcctc gggggcgagc
    19321 cgccgctcgc gctccagccg ggtgcgcagg tcggtgccgc ggacgaggtc catcaccagg
    19381 gccaggtcgt tgccgtcgac cacgaggtcg cgcacggtga cgatgtgcgg gtgctccagg
    19441 ccgagcagcg cggtgcgctc ctggacgaag cgtccgacga gttcctggtc ggaggccagg
    19501 tcctcgcgca gcatcttgac ggcgacgggg ccgtccggtc cctcgcccag ccacaccgtg
    19561 ccggcgctgc cccgccccag gatctggttc gcggtgtacc ggctgccgat cttccgtgcc
    19621 aagactgctc ctacagacgc gcgttgtcgc gtggtgccgt taaaactacg cgtccgacga
    19681 gccaaccttc accgcggaga cggaaatcac ccgccagatg tcgacaaatc cgcaaactcg
    19741 cgatcggata ccggggcgtc ccgggatcag ttgcccgagg agccgcccag gtccttggcc
    19801 cacctgctga tctggccggc ccagtgggtc acctcgtgcc agtagctgcg gccctggccg
    19861 acccaggtgt gcaccggggt cagttcgtag atcagccagc tcgccacgac caggatgacg
    19921 atcgtgaaca ggcagccctt gaggcagccg agccccggga tcttcatcgg gttggcgctg
    19981 cgccggcgcg gttcacgcgg ctcgcgggcg ggacgctgcg gctccggggc gggcgcgtac
    20041 cgctgcggct gctgcggcgg ggcgtactgc tggggctgct gcggcgcata gccgtacccc
    20101 tgctggtacc cgcgcggctg cggctgctgc ggacgggcct gcggggccgg gcgcggctgc
    20161 tgctgggggc gggcgacctg gcgctggggc cggtggtgca gcgggtcgtc ctccggggcc
    20221 aggtactgga tctgggtctg ctcgttgcgg tcgcgcgcgg cgcgcagctg ggtctgccag
    20281 gggtgcggct ggtcgggctg ctgcccctgc gggccggtgt tcggcagcac cgcggtcggg
    20341 tccgccgcgc ccgtgttcgg caggacggcg gtggggtcgg cggcgccggc cggcccgccg
    20401 gtgtgcggca gcacgctggt ggccgcgttc gggtcgtacg cctgctgcgg cgcgttcgcc
    20461 gacagcacct gggtggggtc ggcggcgccg ggcacgcccg gtacggcggt cggcgccggg
    20521 tcgggggcga gcagcgcgcc cacaccctcg gcggcggcga tctgcgcggc gttcgcgtgc
    20581 acgccgatgc cctcggcgac gacacgcaga gcgcgtgcga ggttctcggc gctgggccgc
    20641 tcgtcggggt tcttgcgcag acaccgctct atgaccgtcc acagcgggtc cgggacggtg
    20701 gaggggcggc gcggttcggc gctcaggtgc tggtggagca cctccagggc cgtgctgccg
    20761 gcgaacggcg ggcggccggt gaccagctcg tacagcagga tgccggcgcc gtagatgtcg
    20821 acggcggagg tctgcgggcg gccctcggcg gactccggtg ccacgtacgc gggtgtgccg
    20881 acgaactcct gggtgcgggt caggcccggg gagtcggcga ggcgggcgat gccgaagtcg
    20941 gtcagcatcg ggtgcatctg gccgttgttc tgcgcgagca gcacgttggc gggcttcagg
    21001 tcgcggtgca cgacgccgtc ggcgtggctc gcggcgagcg cgtcggcgat ctgggccgtc
    21061 agcaacgcgg cggcgaccgg ggtgaggggg ccgttctcgc gcaggtagcg gtgcaggtcg
    21121 gggccgtcga cgaggttcat gaccagcgcc agcagatcgc cctcgacgac caggtcgcgg
    21181 acccggacga tgttcgggtg ggtgagccgg
//
