LOCUS       NZ_CP047020            22727 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Streptomyces broussonetiae strain T44 chromosome.
ACCESSION   NZ_CP047020
VERSION     NZ_CP047020.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces broussonetiae
  ORGANISM  Streptomyces broussonetiae
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9735779)
  AUTHORS   Mo,P.
  TITLE     Streptomyces sp. strain T44 isolated from rhizosphere soil of
            Broussonetia papyrifera
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9735779)
  AUTHORS   Mo,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2019) College of Life Science and Technology,
            Central South University of Forestry and Technology, No. 498,
            Shaoshan South Road, Changsha, Hunan 410004, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 25-OCT-2019
            Assembly Method                   :: HGAP v. 3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 12.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009796285.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 17:56:09
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,022
            CDSs (total)                      :: 8,931
            Genes (coding)                    :: 8,515
            CDSs (with protein)               :: 8,515
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 416
            CDSs (without protein)            :: 416
            Pseudo Genes (ambiguous residues) :: 0 of 416
            Pseudo Genes (frameshifted)       :: 171 of 416
            Pseudo Genes (incomplete)         :: 334 of 416
            Pseudo Genes (internal stop)      :: 29 of 416
            Pseudo Genes (multiple problems)  :: 110 of 416
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:31:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 351133
            Orig. end                         :: 373860
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP047020.1.
            Bacteria and source DNA available from Zhao YL.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22727
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iv"
                     /region_number="1"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     cand_cluster    1..22727
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22727
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12727](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12727
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     gene            420..1697
                     /locus_tag="GQF42_RS01790"
                     /old_locus_tag="GQF42_01790"
     CDS             420..1697
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612234.1"
                     /locus_tag="GQF42_RS01790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_01790"
                     /product="IS701 family transposase"
                     /protein_id="WP_158917036.1"
                     /transl_table=11
                     /translation="MDAHEVNRVRAELAIFVADVFSSVPRKDQRAKGDCYLRGLMMDGR
                     RKSIQAMASRLPDGNEQNLQQFVNQSTWDPVPVRRRIAERLVPQIGPDAWAIDDVSFPK
                     DGRMSVGVAPQYCGALGKQANCQVAVSVHAVSDTASCPLNWRLFLPKEWAEDTVRRQRT
                     GVPKDVGHREKWRLALDALDELATWQLVPPVVVADAGYGQNADFRAALAEREIRYVVGI
                     RADLTVQPWDALPDAPAWSGNGRRPVPRYRQPPVPVAELAAAAGPEALSEVTWREGSRG
                     PMTSRFLTVHVRPAGVRPRRLAQQAAVAQHGRWDGVLPEVQLLAEWPDGEDQPTRFWLS
                     DLPDDTPVPELVRLAKIRWRIEHDYRELKHGLGLDHFEGRSWNGWHHHATLVTAAHAFL
                     TEQRLTPKADTADSPSTRSSTPSRTC"
     gene            <1796..>2166
                     /locus_tag="GQF42_RS45415"
                     /pseudo=""
     CDS             1796..>2166
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007383443.1"
                     /locus_tag="GQF42_RS45415"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="HoxN/HupN/NixA family nickel/cobalt transporter"
                     /pseudo=""
                     /transl_table=11
                     /translation="MWFALGHSSVVVVIAALVAGGAKLADTLMNDSSRTHQFLGTVGTT
                     VTGSFLYLIAALNLVALFGILRVFKTMRTGRYDEAELEAHLDSCGSMNRILGRLTKSIC
                     RPARYSRSVSCSGSASTRR"
     gene            2146..>2259
                     /locus_tag="GQF42_RS47130"
                     /pseudo=""
     CDS             2146..>2259
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013629.5"
                     /locus_tag="GQF42_RS47130"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGFDTSTVRYRLGPDHRHYLICTECGLSRPVDSGPVED"
     gene            2618..3262
                     /locus_tag="GQF42_RS01800"
                     /old_locus_tag="GQF42_01800"
     CDS             2618..3262
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013672.5"
                     /locus_tag="GQF42_RS01800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_01800"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_158917038.1"
                     /transl_table=11
                     /translation="MKPTHPGDSHASEPARVELPGSPEFYVHQGPRAIALTIDDGPNPE
                     WTPQVLDLLRRYAVPATFCQVGARVSAYPSLVRAVAAEGHLIANHTWTHADLARASAAT
                     VRSQLERTSDTIEKVTGQRPTIFRAPYGVWSEPTLATCREMGMRLLDWSVDPHDWSRPG
                     ASRIVERIMAHAHPGSIILEHDGGGDRSQTVAALRLVLPRLLEAGYQFVTP"
     gene            3300..>3476
                     /locus_tag="GQF42_RS45425"
                     /pseudo=""
     CDS             3300..>3476
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024736.5"
                     /locus_tag="GQF42_RS45425"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MHPPERSPGPRPLDDRRCLQGVLFVLSTGISWQQLPMELGFGSGQ
                     TCRRRMGRWHEAGV"
     gene            3790..>3867
                     /locus_tag="GQF42_RS47515"
                     /pseudo=""
     CDS             3790..>3867
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039648.4"
                     /locus_tag="GQF42_RS47515"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="transcriptional regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPNKTRARRLTPGPERDKFAADLKMK"
     gene            <3927..4201
                     /locus_tag="GQF42_RS01815"
                     /old_locus_tag="GQF42_01815"
                     /pseudo=""
     CDS             <3927..4201
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014358297.1"
                     /locus_tag="GQF42_RS01815"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="GQF42_01815"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="LLAFYDFPAEHWIHLRTTNPIESAFSTVRLRTKVTRGAGSRTAAL
                     AMVFKSSSPPSSGGGP"
     gene            complement(4198..4968)
                     /locus_tag="GQF42_RS01820"
                     /old_locus_tag="GQF42_01820"
     CDS             complement(4198..4968)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018523579.1"
                     /locus_tag="GQF42_RS01820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_01820"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_158917040.1"
                     /transl_table=11
                     /translation="MSDELLHLTVLGCATPYPSVDNPCSGYLVSSGDTRIWVDAGSGTL
                     GPLQRHVRLDELDAIWISHLHADHSADLLTAYYGALYADIHLAAAIPLYGPPGIADRLA
                     NFLTNTPARSPIESAFAVTELHDGHQAAVGSLRLTSRAVSHGIPAFAVRIEAAGKSLVY
                     SGDTAPCPSLTELAKGCDALLCEAESAQAPVEGEQVHHTPEDTGDTASMAGAGRLIVTH
                     VGRFLTPQQAVARASARFDGPVDYAARDATFSIG"
     misc_feature    5008..5025
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.24"
                     /tool="antismash"
     gene            5051..6370
                     /locus_tag="GQF42_RS01825"
                     /old_locus_tag="GQF42_01825"
     CDS             5051..6370
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1229: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020124631.1"
                     /locus_tag="GQF42_RS01825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_01825"
                     /product="IS630 family transposase"
                     /protein_id="WP_199273015.1"
                     /transl_table=11
                     /translation="MAITLSEAERAELVRRTNMPHRRSAEKARIILACADGMSNARVAR
                     LVGVQAKTVGKWRRAFAAERMAGLEDAGWIGRPKADLILDDAERRQLQQWARQAKTAQF
                     LALRAKIVLRCAEGGTNQQAAADLGIDRSTVDRWRARFIAKRLDGLHDEPRSGRPPSIL
                     LDQVEEVVVATLESLPGQDTHWSRASMAQRTGLSKSTIGRIWKRFDLKPHLQDSFKLST
                     DPQFVAKVVDVVGLYHHPPEKAVVLCVDEKSQIQALDRSQPVLPMMPGMPERRTHDYLR
                     HGITSLFAAFNIADGTVISALHRRHRAIEFKKFLTRIDKAVPAGLDVHLVCDNYATHNT
                     AEIRTWLGKHPRFHVHFTPTGSSWMNQVERWFGLLTDKLIRRGVHTSVKALEDDITAWI
                     NTWNENPRPFTWTKTADEILKSLADYLAKVGTTGQKTEQN"
     misc_feature    5369..5371
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    6398..6411
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.3"
                     /tool="antismash"
     CDS             complement(6782..6934)
                     /gene="allorf_0357915_0358067"
                     /locus_tag="allorf_0357915_0358067"
                     /protein_id="allorf_0357915_0358067"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MDLAALGKEAGGTARPSTASPARNRDRPTAPRCGPNTGRRRTAAH
                     GAGAR"
     CDS_motif       complement(6890..6934)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MDLAALGKEAGGTAR"
                     /locus_tag="allorf_0357915_0358067_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(6782..6889)
                     /prepeptide="core"
                     /locus_tag="allorf_0357915_0358067_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="-3.10"
                     /molecular_weight="3532.9"
                     /monoisotopic_mass="3530.9"
                     /core_sequence="PSTASPARNRDRPTAPRCGPNTGRRRTAAHGAGAR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MDLAALGKEAGGTAR"
                     /leader_location="[6889:6934](-)"
                     /alternative_weights="3550.9"
                     /alternative_weights="3568.9"
                     /alternative_weights="3586.9"
                     /alternative_weights="3604.9"
                     /alternative_weights="3623.0"
     gene            6974..7126
                     /locus_tag="GQF42_RS45435"
     CDS             6974..7126
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GQF42_RS45435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_233273180.1"
                     /transl_table=11
                     /translation="MQFDTEVPGEGTTWGSLDDAVLTSENVLTAAEPVVLATPESGPPT
                     LPTAG"
     gene            complement(<7222..7389)
                     /locus_tag="GQF42_RS47520"
                     /pseudo=""
     CDS             complement(<7222..7389)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013677.5"
                     /locus_tag="GQF42_RS47520"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSGNSGKRYTAELKRDAVELVLSTGRTPTEVARELGASAEGLRSW
                     VKQAKIDRGQG"
     misc_feature    complement(7351..7353)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7434..7568
                     /locus_tag="GQF42_RS46815"
     CDS             7434..7568
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GQF42_RS46815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_267906114.1"
                     /transl_table=11
                     /translation="MSKIRGGTSAPAENCRHLPSLHTPPDLMKVLEASIRAARGDRSS"
     misc_feature    7670..7683
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.17"
                     /tool="antismash"
     gene            7694..7852
                     /locus_tag="GQF42_RS01835"
                     /old_locus_tag="GQF42_01835"
     CDS             7694..7852
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GQF42_RS01835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GQF42_01835"
                     /product="hypothetical protein"
                     /protein_id="WP_199272540.1"
                     /transl_table=11
                     /translation="MTEDVCQAHQYVGTERFEWGLPGERRVVAFIEPTKVRHVVGVEPL
                     PRVRPVQ"
     gene            complement(7938..8672)
                     /locus_tag="GQF42_RS01840"
                     /old_locus_tag="GQF42_01840"
     CDS             complement(7938..8672)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003979485.1"
                     /locus_tag="GQF42_RS01840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_01840"
                     /product="IclR family transcriptional regulator"
                     /protein_id="WP_158917044.1"
                     /transl_table=11
                     /translation="MAGQGSADRKAGEPPLPGRSVLEGAFALLESLADTDETGLAALAA
                     SSGLPKTTAYRLLDQLVALGAVERRGTCYRTGSRMFRLGRGWQPHPGLRAAAQEPLRQL
                     AGATGASVCLCVLREGRTMAAAGIPGIVDELAPVRAGATWPWTTAAGRLLVATGPKALL
                     TGPLPPSWKRQAAEIQQNGVALDREELIPGVCCVAVPVAPPRGEVVGALCAMVEPERDL
                     RRLTHIVTRAGRAIGAGLRQAC"
     misc_feature    complement(8625..8627)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    8719..8730
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     gene            8952..9944
                     /locus_tag="GQF42_RS01845"
                     /old_locus_tag="GQF42_01845"
     CDS             8952..9944
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015983.5"
                     /locus_tag="GQF42_RS01845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_01845"
                     /product="radical SAM protein"
                     /protein_id="WP_233273736.1"
                     /sec_met_domain="PF04055 (E-value: 3.1e-14, bitscore: 52.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 7.3e-07, bitscore: 28.6,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTYSCPLRCVHCYSESGRRPSRQLDHAGILRVADALISLRPLGIA
                     LTGGEPLLVKGLLDVAERIAGAGIPVLLYTSGWNVDQALAADLLGAFHRIAVSLDGATA
                     EVHDRIRGRARSFERAIRTLTLLDEASHDLSVRGRGIAAFGIDCSLMRSNIHQLEAFCT
                     DITPRFPAIRHLIFGVTVPSGLANRAGFAERELLDDDQIRDVASPGRLAHLRSLAPDTV
                     DVSVEDNRMLLMHPDDLAKGRSLPALQVEPDGAVRAMPIYEGTVGNILDEDPSVLWRRA
                     LARRSHPFVVETLTPVRTMREWAQAARRIDQYFGTAEDRARIDRRPAYH"
     gene            10001..12727
                     /gene="lanL"
                     /locus_tag="GQF42_RS01850"
                     /old_locus_tag="GQF42_01850"
     CDS             10001..12727
                     /codon_start=1
                     /gene="lanL"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038150.1"
                     /locus_tag="GQF42_RS01850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_01850"
                     /product="class IV lanthionine synthetase LanL"
                     /protein_id="WP_199272541.1"
                     /sec_met_domain="Pkinase (E-value: 2e-18, bitscore: 65.7,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2e-50, bitscore:
                     170.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAGPTADRSLLVDCVRSVLTRHELSDWQIKPGKFWCHVRLPDAP
                     QRIQGWKLHVSATPLSAPLVLAQTADVLAAHRVPFKFAGTLARVAELCSRRTDRASGGK
                     FITVYPDGPYDQLRALADELHLATEGLPGPGILSDQPYRPGSLVHYRFGAFHGVPMLGN
                     EASYEAMLMAPDGSLDRDRREAWFCPPPWAPRDPFTGQRPTSPKPDRAAARPVRLDDRY
                     VVREVVRHAFTGGVYRATDERDGAAVIVKQARPHTGATASGEDVRDARRHEAAMLEHFA
                     SFGRTPRPVGLFEQQGDLFLVQEAIDGVTLRHWVTQNLTYEEDGGDWGLSVALAERLAA
                     GLVDLVELVHDEGFVLRDLNPNNVMVTEDHELRLIDLELLARPGERVVHAHTPGYAAPE
                     QVDARSGDRCLDLTADLYGLGATLLYLVTGVDPLLAPDDSPARPYRQQIADLLEPLCRD
                     NPTAHRFAPLILALLHEQPEQRPGLAEVRSTLSGQSPPESRSVLPSASNAPTGSELKQL
                     TDDALEHLLATMAPEADRLWPPSSFGATSDPLNVQHGAAGLLGVLTRALCAEPGPHLRE
                     AVGTAADWITGRVGREPRALPGLHFGRSGTTWALLDAAEGLDNDTLAGVAADLARRVPL
                     RWPNPDICHGSAGAGMTQLRFWEATGDDDFLRRADEAAECVAAAAVRRGGLLLWPIPHS
                     WPSHLAGLVHYGFAHGVAGTGAFLLAAGRATGTERYLKLADEAARTLLSTARHDDGAAY
                     WTAGPSGGARRTNWCSGSSGIGTFLLRLSQHSEDVRLREGAEAAAVAVRRSRWHAGTSH
                     CHGLAGDGEFLLDMAEAYRQPRYARWAEDLALTLHARHTIRHGRVLAPDETGTTVTTDY
                     GTGLGGVLAFLLRLRHGGPRLWLPKTFTGPDARDTAR"
     misc_feature    11297..11299
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12767..12880
                     /locus_tag="GQF42_RS44685"
     CDS             12767..12880
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038157.1"
                     /locus_tag="GQF42_RS44685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ALQxL family class IV lanthipeptide"
                     /protein_id="WP_199272542.1"
                     /transl_table=11
                     /translation="MELDVTALQHLQEEEPETGLYPCTFTCPWTSTSAEAE"
     gene            complement(13001..13456)
                     /locus_tag="GQF42_RS01855"
                     /old_locus_tag="GQF42_01855"
     CDS             complement(13001..13456)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GQF42_RS01855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GQF42_01855"
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="WP_158917050.1"
                     /transl_table=11
                     /translation="MQRRTDFVPGDGTTSAFGDGNPEDRCPQLAERIRGAADRVDVVML
                     CEVVDRHRYGHKQLARALADLDLGAALLAPSRSGYGTALLYRWEILSRWRRHSPDFGTE
                     ALHGLAVTSFDIPACAATRGYRYGPPARAALSIMAAALATVDAHLQG"
     gene            complement(13763..15688)
                     /locus_tag="GQF42_RS01860"
                     /old_locus_tag="GQF42_01860"
     CDS             complement(13763..15688)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018559085.1"
                     /locus_tag="GQF42_RS01860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_01860"
                     /product="Ig-like domain repeat protein"
                     /protein_id="WP_158917052.1"
                     /transl_table=11
                     /translation="MRRRSISTATALAVVFSSAALSVMSAGTASAAPASVYAVGGFVVD
                     GATGRVFVGDAETGKVFAADYDGNQVGEADGITDVTDLALSDDGSTLYAAASGSHQIVA
                     LDAATLTVKSRYTVPTTTGPTHVAVAGSKVWFTYGDQWDGNLGSVDPAGAGTVTTGQYT
                     NKLWGQALLDTDPGQPGILAVGETGLSTDSMAVLDVSSGTPQQVAYYHGDYSLNSGIHD
                     IDLVPGGTHVLVNGTERQAYTNGAFAADGAYPNGTDADIAPNGLVAQANGGAVSVYRPD
                     GAVPIRTYNTGSNGAKTPLAWSPDSTELFALVGTNSGWVVTPLGNPTLEQPTLSVHAPS
                     TATGGRQLTVSGTLSTSTQLPAGTRLKVLRTDVENPNGKVLPDATVHADGSYSFTDTPQ
                     AGGTATYKVSYGGDGTHAAATATAQVKVSFATPSLTLNNDGNVYDYNKAVTFTAHLGPT
                     YKNRTVEIWANPYGADKPNKLLKSGTVDSSGNLSVTLNMLRDTDVTAVFKGDTRTAPKT
                     VKSTAYARVAISLAVSRQYRTAKIGTTPYYWFHKNVAPLFTTTMTYYPGRKQRLELQVY
                     VNGKWEADGSKYFSLGTDGRSVVYLPAPGHSGIKARIRSSYINGTSGDTVNKTTYGSWK
                     YLYFTN"
     gene            complement(15880..16053)
                     /locus_tag="GQF42_RS01865"
                     /old_locus_tag="GQF42_01865"
     CDS             complement(15880..16053)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GQF42_RS01865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GQF42_01865"
                     /product="hypothetical protein"
                     /protein_id="WP_158917054.1"
                     /transl_table=11
                     /translation="MRSDLPGIIVLLIRDGLLQVASVSACRRLWRSTASQPEAMPDDAA
                     FSDPDYAMTPLG"
     gene            complement(16120..16614)
                     /locus_tag="GQF42_RS01870"
                     /old_locus_tag="GQF42_01870"
     CDS             complement(16120..16614)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GQF42_RS01870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GQF42_01870"
                     /product="hypothetical protein"
                     /protein_id="WP_158917056.1"
                     /transl_table=11
                     /translation="MQSQGAASPAAGSGNSDGTAQAQALTQAVGDEEFNAAYSEIFGTV
                     IDGYTPGRVALCVTDVTRGRLLAQAAKHAHPAVDLNRLDIFPCRYSEGTLQTAVRGLMA
                     HNRPTIAGFPVYQIGPATDHSGIELRTSQAGRASAALRDYLTSQLGGIAFTVVKGEQAV
                     G"
     gene            17044..17235
                     /locus_tag="GQF42_RS01875"
                     /old_locus_tag="GQF42_01875"
     CDS             17044..17235
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GQF42_RS01875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GQF42_01875"
                     /product="hypothetical protein"
                     /protein_id="WP_158917058.1"
                     /transl_table=11
                     /translation="MFAFLHAGLSPPYGGTIFASMLAVLALAAVFARTPTRRADARKVL
                     DLLLLRGARSTHTNRPQQ"
     gene            17594..18925
                     /locus_tag="GQF42_RS01880"
                     /old_locus_tag="GQF42_01880"
     CDS             17594..18925
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014151564.1"
                     /locus_tag="GQF42_RS01880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_01880"
                     /product="S1 family peptidase"
                     /protein_id="WP_233273181.1"
                     /transl_table=11
                     /translation="MAFALPAAALAAAVPFVIPSLAGASPTPATQAAARIDERQQVLDA
                     IADRITEGLSESGRAHIPGFAEVEVDPDHNHLRLYWKGAPSQRVKSILAHLPHGVTAEV
                     DPARYSRAELHAARVKLLNSLASMKLRVEGTADPVRVTSIAPAVDGSGLEVGYDNAART
                     ASSLLTSGHGKTLQQVATAVGRLSGVHVAAIHRLQSVDLSSRQHDSSPWTGASALKNPL
                     GGICSGSYGVKNARGQYMLTSAYHCGPGPEGQWTTWWGGDLIGTTDATQRSPQDDVVGI
                     KLPSQHVSGRLYDGPASRTDGYAKPVIGWGHNNVGDYVCTDGANGGVHCGVRIAQTDIG
                     VTGPNGIYRPDVDLAYATAATPGGVAAVNGDSGGPVFASVRNHTADEARGIITALDRTI
                     TCPPAYNPGTVLDGHRRTPWCLAGVYYVPIGKTLHDMHWTLVTG"
     gene            complement(19203..19451)
                     /locus_tag="GQF42_RS01885"
                     /old_locus_tag="GQF42_01885"
     CDS             complement(19203..19451)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GQF42_RS01885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GQF42_01885"
                     /product="hypothetical protein"
                     /protein_id="WP_158917062.1"
                     /transl_table=11
                     /translation="MADNDIAVLPPSRSDGFWPCAREQDYGVTLAGKGIRPGQVVCALT
                     AARRVAELRVKAVLRTVSGAPCEILFDVTVWVPPHRT"
     gene            complement(20070..20213)
                     /locus_tag="GQF42_RS01890"
                     /old_locus_tag="GQF42_01890"
     CDS             complement(20070..20213)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GQF42_RS01890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GQF42_01890"
                     /product="hypothetical protein"
                     /protein_id="WP_158917064.1"
                     /transl_table=11
                     /translation="MLVDEFLTAKSGGYPPSKRFMDLLMLRPQFQRPQKTQMAKAELLP
                     FD"
     misc_feature    complement(20210..20223)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.31"
                     /tool="antismash"
     misc_feature    20261..20275
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.19"
                     /tool="antismash"
     gene            complement(20565..20837)
                     /locus_tag="GQF42_RS01895"
                     /old_locus_tag="GQF42_01895"
     CDS             complement(20565..20837)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GQF42_RS01895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GQF42_01895"
                     /product="hypothetical protein"
                     /protein_id="WP_158917066.1"
                     /transl_table=11
                     /translation="MLYFDSDVFVAKAFAVMDDDGSAKVGASVEGQLSAEAQNDLKRLR
                     RTARSHEGKITSVVMCFMADGLPHYWGEEADWHTDLQNDWAEFTQ"
     gene            21049..21859
                     /locus_tag="GQF42_RS01900"
                     /old_locus_tag="GQF42_01900"
                     /pseudo=""
     CDS             21049..21859
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012606252.1"
                     /locus_tag="GQF42_RS01900"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_01900"
                     /product="IS5 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVDDDLWALIEPLLPPWPEKSPGPRGGRPAVSAGHSVRALQRHSL
                     TTPAPELGFGSGQTCWRRLDRWRQAGVFDQLHRILLAELNAAGELDWPRACVDGSHIRA
                     KKGEPTPVRRRSTGGKRAANTI"
     gene            complement(21830..22591)
                     /locus_tag="GQF42_RS01905"
                     /old_locus_tag="GQF42_01905"
     CDS             complement(21830..22591)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891660.1"
                     /locus_tag="GQF42_RS01905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GQF42_01905"
                     /product="SMI1/KNR4 family protein"
                     /protein_id="WP_158917067.1"
                     /transl_table=11
                     /translation="MSGSFDVARALDGGISDRERAWTFIRSFAAAWGDALAEDDGTPRA
                     ELAQAEAMLGCSLPTALHEFYTLVGSRPDLVANQEPLLPPHEVFVHDECGGVLVFRSEN
                     QGCAFWGVRLTDLDRDDPPVLVQARHGWGPFLDRVSLSCVELVLSEALFGGGGRLYNAC
                     ELPADLLGAVPEHFQRVQLPDRPMWTGREEFPVRWFSAPGKLLRQDGLGVHSWLHVRGR
                     TRADLDAICAAVPERWSLGYTESLSSEPLPF"
ORIGIN
        1 gctaggcgcc cgatcgggtg aatgggctgc cagccagtgc ctgccccggg gatgcctcga
       61 tcaaggtcgg cgggcgtgcg tcgaggcctc ccggggggag ctgggagaaa cgacgcggcg
      121 ctgcccggag gctgccacac acggacgcca gccccaggga tgccctcgcc tggccagacg
      181 gaagatcaca tgcccacggg gcgaacggcc gggccgcggc gtgtggaaga aaggccgcga
      241 cgtcctggcc tccaacgacg cgaacgcgcc cgcgtccgca gtgaaaaagg gatccgctgg
      301 ggtggcagac cattgcaacc cgcagcctga ccacgaaccc ggcgaaccta cgcggtcaca
      361 gcactagtag gactccgtta ggtctgtctg cctgcagtgt tcaggggcat gaggactgcg
      421 tggacgcaca tgaagtcaat cgtgttcggg cggagttggc gatattcgtg gcggatgtgt
      481 tctcctcggt accgcggaag gaccagcggg ccaagggcga ctgctatctg cggggactga
      541 tgatggacgg tcgccgcaag tccatccagg ccatggcctc gcggttgccg gacggcaacg
      601 agcagaacct gcagcagttc gtgaaccagt ccacgtggga tccggtgccg gtgcggcgga
      661 ggatcgccga gcggctggtg ccgcagatcg gcccggacgc ctgggccatc gatgacgtgt
      721 cgttccccaa ggacggcagg atgtcggtcg gggttgctcc ccagtactgc ggtgcgctgg
      781 gcaaacaggc gaactgccag gtcgcggtca gcgtgcacgc ggtctccgac acagcctcat
      841 gcccgctgaa ctggcgattg ttcctgccca aggaatgggc cgaggacacc gtccggcgac
      901 agcggaccgg cgtgcccaag gacgtcgggc accgggagaa gtggcgcctc gccctggacg
      961 ccctggatga actggccacc tggcagctgg tgccgccggt cgtggtggcg gacgccggct
     1021 acggccagaa tgccgacttc cgcgccgccc tggccgagcg ggagatccgt tacgtagtcg
     1081 gcatccgcgc cgatctgacc gtccagccct gggacgcgct gcccgatgcc cccgcctggt
     1141 ccggcaacgg ccggcggccg gtgccccgct accggcagcc acccgtgccg gtagcggaat
     1201 tggccgcggc cgccggaccg gaagccctca gcgaggtgac ctggcgggaa ggctcccgcg
     1261 gcccgatgac ctcccgcttc ctcacggtgc acgtccggcc ggccggggtg cgcccgcgac
     1321 ggctggccca gcaggccgca gtggcccagc acggccggtg ggacggcgtc ctgcccgagg
     1381 tgcagctgct ggccgaatgg cccgacggcg aggaccaacc gacccgcttc tggctgtccg
     1441 acctgcccga tgacacaccg gtcccggagc tggtccgcct ggcgaagatc cgctggcgca
     1501 tcgagcacga ctaccgtgaa ctcaagcacg gcctgggcct ggaccacttc gaaggccgct
     1561 cctggaacgg ctggcaccac cacgccactc tggtcaccgc cgcccacgcc ttcctcaccg
     1621 aacagcgact gaccccaaaa gccgacacag cggactcacc ctctaccaga tcctcgacgc
     1681 cctccaggac ctgctgaact gctggaccgg catctgcacc acctgccacc gaccactgcc
     1741 cagcaggacc acgccaagat caagacagac ctaacggagt cctactagat cgaacccctg
     1801 gttcgccctc gggcactcca gcgtggtggt cgtcatagcc gcgctggtcg ccgggggcgc
     1861 caaacttgct gacaccctga tgaacgacag ctcccgaacc caccagttcc tcggcaccgt
     1921 gggcacgacg gtcaccggca gcttcctgta cctcatcgcc gccctcaacc tcgtcgcgct
     1981 gttcggcatc ttgcgtgtct tcaagaccat gcgcaccggc cgctacgacg aggcggagct
     2041 ggaggcccac ctggactcgt gcggctccat gaaccggatc ctcggccggc tcaccaagtc
     2101 gatctgccgc ccggccagat attcccgctc ggtttcctgt tcgggatcgg cttcgacacg
     2161 tcgaccgtcc gctaccgcct cggccccgac caccgccact acctcatctg caccgaatgc
     2221 ggcctgagcc gacccgtcga ctccggcccg gtggaggact gggccgacac cgtggcacgg
     2281 acctccggct tcgcgaacgt ccggcacacg gtggagctgt ccggcatgtg ctcggactgc
     2341 gaccgacggc atgcggcggc cgaacggcac tgaacgcgag caccggctga tgtcggccag
     2401 gggctggttc catcgaatgg gcaaggcccc cagagttcgg cctccaaaga gcgcaaccac
     2461 cctccggggc gatgcagtta ccaaaggcat ggagaacaca ggcaatactc atgtcacccg
     2521 ccggaccctg ctatcagttg gcggattgat gtttctcagc gcctgcacag cccctcgcgg
     2581 tacgcctgaa cacacgggga catcggcacc ggacaccgtg aagcccactc atccgggcga
     2641 ctcccacgcc agcgagccgg cccgcgtcga gttgccgggc agtccggagt tctacgtcca
     2701 tcagggcccg cgagcgatcg cgctgaccat cgacgacggt ccgaaccccg aatggactcc
     2761 gcaggtgctg gacctcctgc gccgctacgc cgtgcccgcc acgttctgcc aggtcggtgc
     2821 ccgtgtcagc gcgtacccca gcctggtgcg ggcagtggcc gccgaaggcc acctgatcgc
     2881 caaccacacc tggacccacg ccgacctggc ccgggcatcc gccgcgaccg tccgctccca
     2941 gctggaacgc accagcgaca cgatcgagaa ggtcaccggc cagcgcccca cgatcttccg
     3001 cgccccctac ggagtctggt ccgagccgac cctggccacc tgccgcgaga tgggcatgcg
     3061 cctgctggac tggtccgtcg acccccacga ctggtcgcga ccgggcgcct cgcgcatcgt
     3121 cgagcggatc atggcccacg cccatcccgg atcgatcatc ctggagcacg acggcggagg
     3181 cgaccgctcc cagacagtgg ccgccctgcg cctggtgctc ccccgcctac tcgaagccgg
     3241 ctaccagttc gtcaccccct aggctttccg cgtttcgtca tcgcgcgcga tgcccgctct
     3301 tgcacccgcc ggagcggtcg ccggggccgc gcccgttgga cgaccgccgg tgcctgcagg
     3361 gcgtcttgtt cgtcctgtcc accggcatct cgtggcagca gcttccgatg gagctgggct
     3421 tcggctcggg gcagacctgc cggcggcgca tgggacggtg gcacgaggcc ggcgtcttcg
     3481 aggccctaac cgacgtgatg ctggtgacca gggcgccccg ggccgacgtg tcagtaactg
     3541 tgctcggggc ggtgtcggac atgagcctgg cgacgacgga gcccggccgg ttccgcgtca
     3601 ccgtgacgcc agcccggccg ccgggcgaag tcactgattc gggccaggca ggcctccaac
     3661 tgggccgggt ccgtgatcgt caccagccgc cccctcttct cctccggacc ttgcgccgaa
     3721 ccggtggccg cggccaccgc cccacgcgat catggcagca accgccgcat gtcagggagg
     3781 aaaccgctca tgccgaacaa gacccgggcc cgccggctca cgcccggccc ggaacgcgac
     3841 aagttcgccg ccgacctgaa gatgaagtac gagggcggga agtccatcag ggccctggcg
     3901 gaggaagcag gccgctccag gaggaactgc tggcgttcta cgactttccg gccgagcact
     3961 ggatccatct gcggaccacg aaccccattg agtcggcctt ctccaccgtc cggctgcgga
     4021 ccaaggtcac ccgaggcgcc ggctcccgca ccgccgcctt ggccatggtc ttcaaatcgt
     4081 cgagtccgcc cagcagcggc ggagggccgt gaacgcgccc cacctcctcg ccctcgtccg
     4141 cgccggagcc cgcttcgaac gtggctgcct tgtcgaacgc cccgaggcag ccgcggccta
     4201 gccgattgag aaggtggcat cgcgggcggc gtagtcgacg ggaccatcga accgtgccga
     4261 ggcacgtgcc accgcttgct gcggcgtgag gaagcggccg acgtgcgtga cgatcagccg
     4321 gcccgccccg gccatgctgg ctgtgtcgcc ggtgtcctcg ggcgtgtggt gcacctgttc
     4381 gccctcgact ggagcctgtg cgctctcggc ttcacacaac agcgcgtcgc atcccttggc
     4441 cagctccgtg aggctcgggc acggtgccgt gtctccggag tacaccagcg acttgcccgc
     4501 cgcctcgatg cgcacggcga aggctggaat gccgtgagac accgcccggc tggtcagccg
     4561 gagcgagcca acggccgcct gatgcccgtc gtgcaactcg gttaccgcga aggcggattc
     4621 gatcgggctg cgagccggag tgttggtaag aaaattggcc agccggtcgg cgattccagg
     4681 cggaccgtag agagggatag ccgctgcgag gtggatgtcc gcgtacaggg ctccgtagta
     4741 cgcggtgagc aggtccgcgc tgtgatcggc gtgcagatgc gagatccaga tcgcatcgag
     4801 ctcatccagc cgcacatgac gctggagcgg gccgagcgtc ccgctgcccg cgtccaccca
     4861 gatacgggtg tccccgctcg acaccagata gccggagcag ggattgtcca cgctcgggta
     4921 gggcgtcgcg cagcccagga ccgtgaggtg aagaagctcg tcgctcatcc caagatccta
     4981 gtgtgatgcg ccagaaatcc tgagggttag ttactaccct gttggcatgt cgcattcggg
     5041 gccttctgct gtggcgatca ccttgtccga agccgagcgt gccgagttgg tgcgccggac
     5101 gaacatgccg caccggcgct cggctgagaa ggcccgcatc atcctggcgt gtgctgacgg
     5161 catgtcaaac gcgcgtgtcg cacggctcgt cggtgtccag gccaagacgg tcggcaagtg
     5221 gcgtcgggca ttcgccgcag agcggatggc cgggcttgag gacgccggct ggatcggccg
     5281 gccgaaggcc gacctcatcc tcgacgatgc tgagcgcaga cagctgcagc agtgggcgcg
     5341 gcaggccaag accgcccagt tcctcgcgtt acgggccaag atcgtgctgc gctgcgcgga
     5401 gggcgggacg aaccagcagg ccgcggccga cctcggtatc gacaggtcga ccgtggaccg
     5461 ctggcgggcc cggttcatcg caaaacgcct cgatggtctg catgacgagc cgcgctcggg
     5521 ccggccgcct tcgatcctcc tcgaccaggt cgaggaggtc gtcgtggcca ccctggagtc
     5581 gctcccgggc caggacacgc actggtcacg ggcctcgatg gcccagcgca ccggcctgtc
     5641 gaagtcgacg atcgggcgaa tctggaagcg gttcgatctc aagccccacc tgcaggactc
     5701 cttcaagctg tccaccgatc cgcagttcgt cgccaaggtc gtcgacgttg tcggcctgta
     5761 ccaccacccg ccagagaagg cggtcgtgct ctgcgtggac gagaagtccc agatccaggc
     5821 gctggaccgg tcccagccgg tgctgccgat gatgccgggc atgcccgaac ggcgtaccca
     5881 cgactatctg cggcacggca tcaccagcct gttcgccgcc ttcaacatcg ccgacggcac
     5941 cgtcatatcg gcactgcacc gccgccaccg ggcgatcgag ttcaagaagt tcctgacccg
     6001 gatcgacaag gcggtgcccg ccgggctcga cgtgcacctc gtctgtgaca actacgccac
     6061 ccacaacacc gccgagatca ggacgtggct cggcaaacac ccccgcttcc acgtccactt
     6121 cacccccacc ggatcctcct ggatgaacca ggtggaacgg tggttcggcc tgctcaccga
     6181 caaactcatc cgccgcggcg tccacacctc cgtgaaggca ctggaggacg acatcaccgc
     6241 atggatcaac acctggaacg agaacccgcg acccttcacc tggaccaaga ccgccgacga
     6301 gatcctcaaa tccctcgccg actacctcgc caaggtcgga accaccggcc agaaaacaga
     6361 gcagaactaa ccctcaggat ttctggcgca tcacactaga acacacgatc cacaagtctt
     6421 gacgattact ccttcaatgc gccgcggacg gccagcgcga ggctcttcgt cttctccatg
     6481 cgggcctggt gaagggcgcg gttctgggct gcggccttct cgcgtccctt gcggccctcg
     6541 cggccttctc gcgctcttgg gcttcgcgcc tggcggccct ctcgcgctcc cgagccgccc
     6601 gttgctgctc ctcgacgcgc cgaaggtgcg cctgggcggc agcgacggcc tctctttctt
     6661 ctgccgaggc gtcaggatcc ctgatcaggt catcggcctg ccagtacagc tgggggtcgg
     6721 ctgctccttc agccgctcca caacatccct ccgacgtcgt gcacgctcct gcagccagcg
     6781 ctcaccgcgc cccagcgcca tgcgcagccg tgcgtcgtcg gccggtgttg ggcccgcatc
     6841 gaggagctgt cggacggtct ctgttgcggg caggactcgc cgtggatggt cgcgcagtgc
     6901 ccccggcctc cttgcccagc gcggctaagt ccaccggatc cggttcgacg accggcccgg
     6961 gggcggcaga accatgcagt tcgacaccga ggtccccggc gagggaacca cctggggcag
     7021 cctggacgac gcagttctca cctccgagaa cgtgctcact gctgctgagc ctgtcgtcct
     7081 tgccacgccc gagtccgggc ctcccaccct gcccaccgca ggctgaacca ggtccgccac
     7141 cagccccacc gcgacctgac acaccatcaa caacccacca tcccgacaag ttgacaacgc
     7201 cctggtcagc gcaccggccg gcccctgacc ccggtcgatc ttcgcctgct tcacccagct
     7261 gcgcagccct tcggcactgg ccccgagctc ccgggccact tccgtcgggg tccgcccggt
     7321 ggaaagcaca agctccaccg cgtcccgctt taactcggcc gtgtaccgct taccactgtt
     7381 gccactcacg atctggacta cttcctccgg gacccaaccg tcccagtatc aggatgtcca
     7441 agatccgagg gggaacatca gcaccggccg agaactgccg gcacctgccg agcctgcaca
     7501 cgccgccgga tctgatgaag gtgctggagg cgagcatccg ggccgcccgc ggcgaccgca
     7561 gctcgtaagc agtgtgaacg ggttcgattc ggcggctcgc cgtcgaaagc cgtcacgcgg
     7621 accggtcgat ctggtcgatc tggctcctgc cccggccgct ttcgttatct gttgtcaatc
     7681 aaagcagcgg gtcatgaccg aggatgtctg tcaggcacat cagtacgtcg gcaccgagcg
     7741 gttcgagtgg ggactcccgg gcgaacgacg tgtcgtcgcc ttcatcgagc ctacgaaggt
     7801 acggcacgtc gtcggcgtcg aacccctgcc ccgggtgcgc ccggtgcagt agagccccgc
     7861 ccgcgcggtc gggagacgta ctggccacgg gcatgacgca tcgggcacgg cagcgcatgg
     7921 gccggcgccg aaggccctca gcacgcctgc cgcaggcccg cgccgatcgc ccggcccgct
     7981 cgcgtgacga tgtgtgtcag ccgtcgtaga tcccgttcgg gttcgaccat cgcgcacagg
     8041 gcgccgacga cttcgccgcg cggtggcgcc acgggcacgg cgacgcagca cacgccgggt
     8101 atcagttcct cgcggtccag ggcgacgccg ttctgctgga tctccgctgc ctgccgcttc
     8161 caggagggcg gcagcgggcc cgtcaggagg gccttcggtc ccgtcgccac gagcagtctt
     8221 cccgctgcgg tggtccacgg ccaggtcgcg ccggctcgca caggggccag ttcgtcgacg
     8281 atgccgggaa tccccgcggc cgccatggtg cggccttccc gcagcacaca cagacagacg
     8341 ctcgcaccgg tcgcaccggc gagttgccgc agcggttcct gggctgcagc ccgcaggccg
     8401 gggtgtggct gccatccccg gcccaggcgg aacatccgtg aaccggtccg gtagcacgtg
     8461 ccgcggcgtt ctacggcacc gagcgcgacg agttgatcca gcagcctgta ggcggtcgtc
     8521 ttgggcaagc cgctgctcgc ggccagtgcg gccagacccg tctcgtccgt gtccgccaat
     8581 gactccagca gcgcgaacgc cccttcgaga acgctgcgtc cgggtaacgg tggttccccg
     8641 gccttccggt ctgccgaccc ctgtccagcc atggggccaa ccccctttcc actccgtgag
     8701 cgagtcaagg cgacggcgat agacgaacgc tgtccgatgg gtaaacccgc tggtgagggt
     8761 gcatgtggct gggaatgtac ggccgcgccc ggcgtaccgt tccgctcagc ggaacgcgcc
     8821 tcgttcagcc gtcctcggcg ccgctatggt cccttcgcga gtcaattccc gtgccgttgt
     8881 gccaacgggt atgtgtggga ggggaatatc cgatgagtgc gccgagcggc cccacagatg
     8941 tcatctggga catgacctat tcctgtccgc tgcgctgtgt gcattgttat tcggagtctg
     9001 gtcggcggcc gtctcgacaa ctcgaccatg ccggaattct ccgagtggcc gatgcgctga
     9061 tttccctgcg gcctctgggt atcgccctga ctgggggcga gccccttctc gtcaaaggcc
     9121 tgctcgacgt cgcagagcgc atcgcgggtg cgggcattcc cgtcctgctc tacaccagcg
     9181 gctggaacgt cgaccaggcc ctggccgcag acctcttggg cgccttccac cggatcgccg
     9241 tgagcctgga cggtgccacc gccgaggtgc atgaccggat caggggccgc gcgcggtcct
     9301 tcgagcgcgc gatcaggacg ctcaccctcc tcgacgaggc ctcccacgac ctcagtgtac
     9361 gtggccgcgg gatcgccgcc ttcgggatcg actgctcgct gatgcggagc aacatccatc
     9421 aactggaggc attctgcacg gacatcacgc cgcgctttcc cgccatacgg cacctgatct
     9481 tcggcgtgac ggtgccctcg gggctggcca accgggccgg gttcgccgaa cgcgagctcc
     9541 tcgacgacga ccagatccgc gatgtggcga gccccgggcg gctcgcacac ctgcgctccc
     9601 tcgctccgga cacggtggac gtctccgtcg aggacaaccg catgctgctc atgcaccccg
     9661 acgacctcgc caaggggcgg tcgctgccgg ctctgcaggt ggagccggac ggcgcggtgc
     9721 gggccatgcc gatctacgag ggcacagtgg gaaacatcct cgacgaggat ccgtccgtcc
     9781 tgtggcggcg ggccctcgca cggcgcagcc atcccttcgt cgtggagaca ctgacgcccg
     9841 tgcgcaccat gcgggaatgg gctcaggccg cgcggcgcat cgaccagtac ttcggcacgg
     9901 ccgaggaccg cgccaggatc gacaggcggc ccgcgtacca ctgacgcgtt ctcgccgacc
     9961 tctccctcac gctgccggta ccggatgaag gggtgaaacc atgaaagcgg gccccaccgc
    10021 ggatcgttcg ctgctcgtgg actgcgtccg ttccgttctc actcgtcatg aattgagcga
    10081 ctggcagatc aagccaggta aattctggtg ccacgtccgt ctgccggatg cgccgcagcg
    10141 cattcagggg tggaaactgc acgtttctgc aacgcccttg tccgccccgc tcgttctggc
    10201 ccagacggcc gatgtcctgg ccgcccatcg cgtgccgttc aaattcgccg ggactctcgc
    10261 ccgggtggcg gaactctgct cccgccgtac ggaccgggcc agcggcggaa aattcatcac
    10321 cgtatatccg gacggtccct acgaccagct gcgcgcgctc gcggacgaac tgcacctcgc
    10381 caccgagggt ttgccggggc ccggcatcct ctcggaccag ccgtaccggc ccggcagcct
    10441 ggtgcattac cgtttcggag ccttccacgg agtgcccatg ctcggcaacg aggcgtcgta
    10501 cgaggccatg ctgatggcac cggacggctc cctggaccgg gaccggcgtg aggcctggtt
    10561 ctgcccgccg ccgtgggcgc cgcgcgatcc gttcaccggg cagcggccca catcgcccaa
    10621 gcccgacagg gccgctgccc ggccggtacg cctcgacgac cgttacgtcg tccgcgaggt
    10681 cgtccgccac gccttcaccg gcggtgtcta ccgtgcgacg gacgaacggg acggcgccgc
    10741 cgtcatcgtc aaacaagcgc gcccccacac cggggccaca gcgagcgggg aggacgtccg
    10801 cgacgcgcgg cgccacgagg cggcgatgct ggagcatttc gcgtcctttg gccgcacacc
    10861 gcgaccggtc gggctcttcg aacagcaggg tgatctgttc ctcgtccaag aggcgattga
    10921 cggggtcacc ctccgccact gggtgacgca gaacctcacc tacgaggagg acggcggcga
    10981 ctggggcctg tccgtggcgc tcgccgagcg gctggccgcc ggcctggtcg acctggtgga
    11041 gctcgtccac gacgagggct tcgtcctgcg cgatctcaac cccaacaatg tgatggtcac
    11101 cgaggaccac gagctgcggc tgatcgatct cgaactcctg gcccgccccg gcgaacgcgt
    11161 ggtgcacgcg cacacaccgg gctacgcggc acccgagcag gtcgacgccc gctccggcga
    11221 ccgctgcctc gatctcaccg ccgacctcta cggcctcggc gccacgctgc tgtacctggt
    11281 cacgggtgtg gacccgttac tcgctcccga cgactcgccc gcgcggccct accggcaaca
    11341 gatcgccgac ctcctcgaac ccctgtgccg tgacaacccc accgcacatc gtttcgcacc
    11401 gctcatcctc gcgctgctcc acgagcagcc cgaacagcgg cccggcctcg cggaggtccg
    11461 gagcaccctg agcggccagt ccccgcccga gtcacgttcc gtcctcccat cggcgtcgaa
    11521 cgcgcccacc ggcagcgaac tcaaacagct gaccgacgat gccctggagc atctgctggc
    11581 gacgatggcc cccgaggccg accggctctg gccgccgtcg tcgttcggcg ccaccagcga
    11641 tcccctcaac gtccagcacg gcgccgcagg cctcctcggc gtgctcaccc gcgccctgtg
    11701 cgccgaaccc ggaccgcacc tgcgcgaggc cgtcggcacg gccgccgact ggatcaccgg
    11761 ccgcgtcggg cgtgagccgc gcgcgctgcc cggcctgcac ttcggccgct ccggtaccac
    11821 ctgggccctc ctcgacgccg ccgagggcct cgacaacgac acactggccg gcgtcgcggc
    11881 cgacctggcc aggcgggtcc cgttgcgctg gcccaaccct gacatctgcc atggctcagc
    11941 cggggccggt atgacccagc tccgcttctg ggaggccacc ggcgacgatg atttcctccg
    12001 cagggccgac gaggccgccg agtgcgtggc cgccgcggcc gtccgccggg gcggactgct
    12061 cctgtggccc atcccgcact cctggccgtc ccacctcgcc gggctcgtgc actacggctt
    12121 cgcccacggc gtcgcgggca ccggcgcgtt cctgctcgcc gcgggccggg ccaccggcac
    12181 tgagcggtat ctgaagcttg cggacgaagc cgcacgcacg ctcctgtcga cggcacgtca
    12241 cgacgacggc gctgcctact ggaccgccgg gccctcgggc ggggcacgca ggaccaactg
    12301 gtgcagcggc tcctccggga tcggcacctt cctgctgcgg ctgtcccagc acagcgagga
    12361 cgtccgcctg cgcgagggtg ccgaggcggc cgccgtcgcg gtccgccgtt cccgctggca
    12421 cgcgggaacc tcccactgcc acggactggc gggcgacggc gagttcctgc tcgacatggc
    12481 cgaggcctac cggcagccgc gctacgcccg ctgggccgag gacctcgccc tcaccctcca
    12541 cgcccgccac accatccgcc acgggcgcgt gctcgccccg gacgagaccg gaacgaccgt
    12601 cacgaccgac tacggcaccg gcctcggcgg tgtactggcc ttcctgctgc gactgcgaca
    12661 cggcgggccc cgcctgtggc tgcccaagac gttcaccggg ccggacgcac gcgacacggc
    12721 caggtgaacc agcacaccgg accggacccg gagggaggtg agacagatgg agcttgacgt
    12781 gaccgccctg cagcacctgc aggaggaaga gcccgagacg ggcctctacc cgtgcacgtt
    12841 cacctgcccg tggacctcga cgtccgcgga ggccgagtaa gcacaccgca cggccggcga
    12901 gcggcggccc tctcccagga gatctctcgg gagggggccg acccgcgcct gggcgcaggc
    12961 tgcccgcagt ggtcatcacc gtcatcgcga cgccggatgc tcacccctgg agatgcgcgt
    13021 ccacggtcgc cagcgccgcc gccatgatgc tcagcgcggc gcgagcaggg ggcccgtagc
    13081 ggtagccgcg ggtggcagcg caggccggga tgtcgaagct ggtcaccgcg agcccgtgca
    13141 gggcctcggt gccgaagtcc gggctgtggc gacgccagcg gctcaagatc tcccagcggt
    13201 agagcagcgc ggtgccgtag ccgctgcgtg acggggcgag cagggccgcg ccaaggtcca
    13261 ggtccgccag ggcgcgggcg agttgcttgt gcccgtaacg gtgccggtcg acgacctcgc
    13321 acagcatgac gacgtcgacg cggtcggcgg cgcccctgat ccgctcggcg agctgcgggc
    13381 agcggtcttc ggggttgccg tccccgaagg cactggtcgt gccgtctcca ggaacgaagt
    13441 cagttcggcg ttgcaacggg ccgggttctc cgcgttcgga ttcatcgcgg cctcgggcac
    13501 cgtggtggtg cgcccatcgg gcaagatgag acgggtgcag gcgctcagcc ggcgagcgcg
    13561 ccccggtcct ccgccgctcc cgcgcctcct gtcccgccca cttcgcgcac gcctggagca
    13621 acgcgggcct cgcgaggcga agcggccctg cgctcggttc ccagccggcc gaactcccgc
    13681 agggtgtcca ggcaggtgcc ggtgtggccc tgccgtccct cgtgcgcgag gggcggcggg
    13741 gccaaccggg tgccggatag ggctagttgg tgaagtacag gtacttccag gatccgtacg
    13801 tcgtcttgtt cacggtgtcg ccggaggtgc cgttgatgta cgaggaccgg atccgtgcct
    13861 tgatgccgga gtggccgggg gccgggaggt agacgacgga cctgccgtcc gtgcccaggc
    13921 tgaagtactt ggaaccgtcc gcctcccact tgccgttgac gtagacctgt agttcgaggc
    13981 gctgcttgcg gcccgggtag taggtcatgg tcgtggtgaa caggggtgcg acgttcttgt
    14041 ggaaccagta gtaaggggtc gtgccgatct tcgccgtcct gtactgccgg gagaccgcga
    14101 gggagatggc cacgcgcgcg tacgccgtgg acttcaccgt cttgggcgcg gtgcgggtgt
    14161 cccccttgaa gacggcggtg acgtccgtgt cccggagcat gttgagggtg acggagaggt
    14221 tgccgctgga gtcgacggtg ccgctcttca acagcttgtt gggcttgtcg gcgccgtagg
    14281 ggttggccca gatctcgacc gtgcggttct tgtaggtcgg gccgaggtgc gcggtgaagg
    14341 tgacggcttt gttgtagtcg tacacgttgc cgtcgttgtt cagggtcagg ctcggcgtcg
    14401 cgaaggagac cttgacctgg gcggtggcgg tggccgccgc gtgggtgccg tcgcccccgt
    14461 aggagacctt gtaggtggcg gtgccgccgg cctgcggggt gtcggtgaag gagtacgagc
    14521 cgtcggcgtg cacggtggcg tcgggcagca ccttgccgtt cgggttctcc acgtcggtgc
    14581 ggaggacctt cagcctggtg ccggcgggca gctgcgtcga cgtcgacagg gtgccggaga
    14641 cggtgagctg cctgccgccg gtcgcggtgg acggggcgtg caccgacagc gtgggctgct
    14701 ccagcgtcgg attgccgagc ggagtgacga cccagccgct gttggtgccg acgagggcga
    14761 acagctcggt ggagtccggg gaccaggcca gcggggtctt cgccccgttg gagccggtgt
    14821 tgtaggtacg gatcggcacg gcgccgtccg gccggtagac cgacacggcg ccgccgttcg
    14881 cctgcgcgac cagcccgttc ggggcgatgt cggcgtcggt cccgttcggg taggcgccgt
    14941 cggcggcgaa cgcgccgttc gtgtacgcct gccgctcggt gccgttgacc agcacgtgag
    15001 tgccgccggg caccaggtcg atgtcgtgga tgccgctgtt gagcgagtag tcgccgtggt
    15061 agtacgcgac ctgctgcggc gtgcccgagg agacgtcgag gacggccatc gagtcggtgg
    15121 acagaccggt ctcaccgacg gcgaggatgc cgggctggcc ggggtcggtg tcgagcagcg
    15181 cctggcccca gagcttgttg gtgtactggc ccgtcgtcac cgtgccggcg ccggccgggt
    15241 cgaccgaacc gaggttgccg tcccactggt cgccgtacgt gaaccacacc ttgctgccgg
    15301 ccacggccac atgggtcggg ccggtggtgg tgggcacggt gtagcgggac ttgacggtca
    15361 gggtggccgc gtccagcgcc acgatctggt ggctgcccga ggcggccgcg tacagcgtgc
    15421 tgccgtcgtc ggacagcgcg aggtcggtga cgtcggtgat gccgtccgcc tcgccgacct
    15481 ggttgccgtc gtagtcggcg gcgaagacct tgccggtctc cgcgtcgccg acgaagaccc
    15541 ggccggtcgc gccgtcgacg acgaacccgc cgaccgcgta cacggaggcg ggagccgccg
    15601 aggccgtacc ggccgacatc acgctcagcg ccgccgagct gaagacgacc gcgagcgccg
    15661 tcgcggtcga gatgctgcgc cttcgcacag ttgtgtaacc cccacgagga gtcccggcct
    15721 gaggccggga gccgatggcg ccgcgcatcg cccggccgtg accgaaaagg tgcggtgacg
    15781 accggggcgc gactgccagc ggcagcgtat gacacgagtg tgacagtcga cgagcgggaa
    15841 tggttgtgcg ccaggaggga cagcctggat cggggtggct caacccaggg gtgtcatcgc
    15901 gtagtccggg tctgagaacg ccgcgtcgtc aggcatcgct tccggctgcg aggccgtact
    15961 gcgccagagc cgccgacagg ccgagaccga cgccacctgc agcagcccgt cgcggatcag
    16021 cagtacgatg atgcccggca gatcgctgcg cacgacctgg ccttggccag ggtcgcacca
    16081 tggccaagga ctctgtcggg tggtggcgaa acggccgcct catccgaccg cctgctcacc
    16141 cttgacgacg gtgaaggcga taccgcccag ctgcgaggtg aggtagtcgc gcaaggctgc
    16201 tgaggcgcgg cctgcctggc tggtccgcag ttcgatgccg gaatggtccg tggccgggcc
    16261 gatctggtag acggggaacc ctgcaatcgt cgggcggttg tgtgccatga gcccgcggac
    16321 ggccgtctgc agtgtcccct cggagtagcg gcaaggaaag atgtcgagcc ggttgaggtc
    16381 gacggccggg tgggcgtgct tggccgcctg ggcgagcagc ctcccgcgcg tcacgtccgt
    16441 gacgcacagc gccacccgcc ccggggtgta gccgtcgatc accgtgccga aaatttccga
    16501 gtacgcggcg ttgaactcct catcgccgac ggcctgcgta agcgcctggg cctgcgcggt
    16561 gccgtcggaa ttgccactgc ccgcagcggg ggaggccgca ccctgactct gcacgccatc
    16621 cgggcaggag gcggtagccc cgccgctgct cgggatcctg ctgctgccgg cccaggacac
    16681 ggacggggcg ctggcagacg gcgtccgtga cgccgccgat gtccccagcg aggacccggc
    16741 gcacgccgca gtggcagcca acatccccga acagagcgtc acagcaacag cgcgccgcat
    16801 catgttcctt cttccccgga gttcagttcg cgggctgttg tcgctcatgg cttcccctgc
    16861 ctgccgcccc atccgggtgc atccggttct atccaggcca tgcgtgaagg ataggcaccc
    16921 catcggggcc ggatcagccg ccagcgggaa cgtccgagaa gatcgccgga ggcgactgcg
    16981 gcatggggcc atagggagca ggcaccggga aggcccgggc catgctcctc acttgggatc
    17041 accatgtttg cctttctcca cgccgggctc tcgcccccct acggcggcac catcttcgcc
    17101 agcatgctcg cggtcctcgc cctcgccgca gtcttcgccc gcacacccac ccgccgggcc
    17161 gacgcccgca aggtcctcga cctcctcctt ctacgaggtg cgcggtcgac acacaccaac
    17221 aggccgcagc agtgatccgc agccggccca ctcggcagtc gggtcctcac aggtcgagac
    17281 gtacgaggcc gccaggaacg gcaggcctcc acaacgtcgg gttgcccgtc gcgaacatcc
    17341 gccggcggcc gaatctccgc cgacgacacg gcaggcccca tccatgtcga ggtcgttggg
    17401 gagctgtttg ggcagctggc cggagagcaa caggcgccgt ctgcctcagc cctgcggctg
    17461 ccgatcagga accttctctc gcctacctga tcacaatttt gtctgacgag cctgccgtag
    17521 gagcatgtcc gcgtcacaat ggctccagca gaaagacagc ggccatatga aacacgctgc
    17581 acgtcacaga tgggtggcat tcgcgctgcc ggccgcggcc ctggcggccg cagtcccgtt
    17641 tgtcatcccc tcactcgcgg gcgcctctcc tacgccggcc acacaggcag ccgcgcggat
    17701 cgacgaacgc cagcaggtcc tcgacgccat tgccgaccgg atcaccgaag ggctctccga
    17761 gtccggcagg gcgcacatac ccggcttcgc cgaggtggag gtcgaccccg accacaacca
    17821 cctgcgcctg tactggaaag gcgccccgtc ccagcgggtc aagagtatcc tcgcccacct
    17881 cccccacgga gtgaccgccg aggtcgaccc tgcccgctat tccagggccg aactccacgc
    17941 ggcccgcgtg aagttgctga acagcctggc ctccatgaag ctgcgagtcg aggggacggc
    18001 ggaccctgtc cgcgtcacca gcatcgcacc ggcggtggac ggcagcggcc tggaggtcgg
    18061 ctacgacaac gccgcccgca cggcgagcag tctcctgacg agcggacacg gcaagacgtt
    18121 gcagcaggtc gccacggcag tcggccgcct gtcgggagta cacgtcgccg cgatccaccg
    18181 gctgcagagc gtggatctgt cctcccggca gcatgacagc tccccctgga ccggagcctc
    18241 ggcgctgaaa aacccactcg gcggcatctg ctccggctct tacggcgtga agaacgcccg
    18301 gggccagtac atgctgacgt cggcctacca ctgcggcccc ggccctgaag gccagtggac
    18361 cacctggtgg ggtggcgacc tcatcggcac caccgacgcc acccaacgct ccccccaaga
    18421 cgacgtggtc ggcatcaagc tgccctcaca gcacgtgagc ggccggctct acgacggccc
    18481 cgcaagccgc accgacggct acgccaagcc cgtcataggc tgggggcaca acaacgtcgg
    18541 cgactacgtg tgcaccgacg gcgccaacgg cggcgtgcac tgcggtgtgc gcattgccca
    18601 gaccgacatc ggcgtcaccg ggcccaacgg catctaccgc cccgacgtcg acctcgccta
    18661 cgccaccgcc gccactcctg gcggcgtcgc agccgtcaac ggcgacagcg gcggcccggt
    18721 cttcgccagc gtccgcaacc acacagccga tgaggcacgc ggaatcatca ccgccctcga
    18781 ccggaccatc acctgcccgc ctgcgtacaa ccccggcacc gtcctcgacg gtcatcgcag
    18841 gacaccctgg tgcctggccg gcgtctacta cgtacccatc ggaaaaaccc tccacgacat
    18901 gcactggacc ctggtcaccg ggtgaccctt cacaggccca gggccgcagc ggggccgaga
    18961 atgagacagc cgacaccgac cgcagcgacc ggctgtccgt gccggcccga gcaccgctga
    19021 agtccagcac cccacgcgac ccggccgcct cggccgcgtt catcaacgcg gcctccaccc
    19081 cgagccgaac accggtggcc cggtgtggag accgccctca tcgaggcggg aagccgaggg
    19141 atggcgggac aggcgagttc gcagtccgtc aagcgaagag gtcggcgcgg ccatccgtct
    19201 ggtcaggtcc ggtgcggcgg cacccacacg gtgacgtcga acaagatctc gcatggcgcg
    19261 ccggacaccg tacgcagcac ggctttcacc cggagctcgg ccacgcgacg ggcggctgtg
    19321 agagcgcaca cgacctgtcc gggacggatg cctttaccgg cgagcgtcac tccgtagtcc
    19381 tgctcgcgtg cgcacggcca gaagccgtcg gaacgactcg gcgggagcac ggcgatgtcg
    19441 ttgtccgcca cgccgtgcag ggcgtggtcc tgggcgccga atcagatgtc cgccgtggcg
    19501 ggtcccggct cgggccgtac atcccagtcc gcagccatcg agtccaggtc ggccacctgc
    19561 ccgggcctca gggtcagcgt gtcgcgccgg cgcacggggg caggcgcacc ctctggcagg
    19621 gcggcggccg cgtgcggcga cgccgatccg gcggacaccg ttggccgagc gccggacgcc
    19681 ccgctcagcc ccgccagcag cgcggcgagc agcactgcgg cagctaccgc ccaggccagt
    19741 cggccggctc gcgccacccg tcgccgaagc gccgtcagcg gacggcggcc aactgcggac
    19801 cgatcggaga caccggttac ggggacgggt ttcggctccc gggcggcctc cgacggcgag
    19861 gtcggcggta cagccggagg cagtatggcg ggtggttccc cgtcggttgc gggccggagc
    19921 tgctcccacc gccggcgcca cagctcatga cctcagcgag gacctcccgg tcgatgtagc
    19981 cgtcgacggc ttccatcacc acacgcttga gctcggcccg cttcggccgg aagcacgggt
    20041 atgcctcccg cccggcagtt cccgagaact cagtcgaacg gcagtagttc ggcctttgcc
    20101 atctgcgtct tctgcgggcg ctggaactgc ggcctgagca tcaacaggtc catgaaccgc
    20161 ttcgacggtg ggtagccgcc tgacttcgcg gtgaggaact cgtcgacgag caaggttcgt
    20221 gccttcgccg tggtgacgcc ggtgaggacg ttctgctggg tgatctcgtc ggccagggcc
    20281 tcaaggtccc gctcgtagcc ggcgtagata cggcgggacg cttcctcgac gagttcgatg
    20341 gcctggctcg tggcccagcg gacgatgcgc tggtgttcgt gcagtgcctc gtcgtcggcc
    20401 ccgtcgggcg gtgggcaggc gccgtaggcg atgccgtgat gatgtgatcg cttcgttgcg
    20461 gcccggaact ccggattgtc ggcgagttcg gccgcaatcc gctcggcctc ggcgtcggcc
    20521 tgcaggcggg cgtcctggac gcgttcggcc gcggagaggc ggtgctactg ggtgaactct
    20581 gcccagtcgt tctggagatc ggtgtgccag tcggcctcct cgccccagta gtggggcagt
    20641 ccgtcggcca tgaagcacat caccaccgag gtgatcttcc cttcgtggga acgcgcggtt
    20701 cggcgcagcc gcttcaggtc gttttgagcc tctgcgctca gctggccctc gacactggct
    20761 ccgaccttgg cggacccgtc gtcgtccatg acggcgaacg ccttcgcgac gaacacgtcg
    20821 ctgtcgaagt acagcacccg cgtgccgcac gtgtgggcga cgtcgatgaa ctcttcggcg
    20881 tcgaactcat cccccggcag cagtacccgg cagccctctc cctccgggat ggcagccagg
    20941 ggtttcagcc ccttcgagct cgtaacacga tcttgttgaa gtggcccggt tgggcgtgac
    21001 cgatgtgacg attcggccgt tcgggagggt gtgagtaccc ggccgtggat cgtggacgac
    21061 gacttgtggg cgctgatcga gccgctgctg ccgccctggc ccgagaagtc gccgggcccg
    21121 cgcggtggca gaccggcggt gtctgcaggg cattctgtac gtgctctaca acgacatagc
    21181 ctgacaactc ctgccccgga gctggggttc ggctccggac agacctgctg gcggcgcctg
    21241 gaccgctggc ggcaggccgg ggtcttcgac cagctgcacc gcatcctgct cgccgaactc
    21301 aacgcggccg gcgaactcga ctggccccgc gcctgcgtgg acggctccca catccgagcg
    21361 aaaaaggggg agccaacccc ggtccgtcgc cggtcgaccg gcggaaaacg ggcagcaaac
    21421 accatctgat ctgcgacgga cgcggcaccc cgctcaaagt catcaccact gcggccaacg
    21481 tcaatgacgt cacccagacc ctcactctcg tcgatggcat cccgcccgtg gccggacggc
    21541 ccggccgccc gcgccgccgc cccgactcac ttctcggcga caagggctac gactccaccg
    21601 gcgcgagctg cgcaagcgcc ggattctgcc ggtcatctcc cgcaagggcg ccccgaacat
    21661 caagggcctc ggcaaactcc gctacgtcgt cgagcagacc ttcgccctgc tccaccagtt
    21721 caagcgcctc gccgtccgct gggaacgccg aaccgaactc cacgatgcct tcgtctcgtt
    21781 ggcctgtagc ctcatctgct ggagacgcct caaggaggtc cgcagcagat cagaagggca
    21841 gcggctcgga gctgagtgac tcggtgtacc ccagggacca ccgctcagga acggcggcgc
    21901 agatcgcatc cagatcggcg cgggtccggc cccggacgtg aagccagctg tggacgccca
    21961 ggccatcttg gcgcagcagc ttgcccgggg cagagaacca acgcacgggg aattcctccc
    22021 gccccgtcca cattggacgg tccggcagtt ggacccgctg gaagtgttcg ggcaccgcac
    22081 caagcaggtc cgcgggcagc tcgcacgcgt tgtacagccg gcctccgccg ccgaacagcg
    22141 cctcgctcag gacgagttcg acgcaggaca aggacacccg gtccaagaac ggcccccagc
    22201 cgtgccgcgc ctgaacgagc accggaggat cgtcccggtc aaggtcggta aggcgcaccc
    22261 cccagaaggc acagccctgg ttctcactgc ggaagacgag gacgccgccg cactcgtcat
    22321 gcacgaacac ctcgtgaggc ggcagcagcg gctcctggtt ggcgaccagg tcgggccggc
    22381 tacccacgag cgtatagaac tcgtgcagcg cagtcggcag ggagcagccg agcatcgcct
    22441 ccgcctgcgc cagctccgcc ctgggcgtgc cgtcatcctc ggccagcgca tcgccccaag
    22501 cggcagcaaa gctgcggata aatgtccagg cccgctcccg atcggaaatg ccgccatcca
    22561 gggcgcgggc cacgtcgaag ctgccactca tgccacgaaa cgtatcggaa gcccgagccg
    22621 catcgccaag agaccatcag gccgccagag agagtcgcaa ctggggcccg gacctgatct
    22681 cgctggcgcc gaaccccgcc gtcaccggcc tcgccgccct ggtgctg
//
