GCF_009758095.1 - 3 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP046629.1 (Streptococcus equinus (Streptococcus bovis))

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1.1	RiPP-like	410,993	423,817
Region 1.2	lanthipeptide-class-ii,terpene-precursor	1,121,517	1,154,930	Medium	streptococcin A-FF22	ribosomal:RiPP:Lanthipeptide
Region 1.3	T3PKS	1,656,405	1,697,583

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1.1	RiPP-like	410,993	423,817
Region 1.2	lanthipeptide-class-ii,terpene-precursor	1,121,517	1,154,930	Medium	streptococcin A-FF22	ribosomal:RiPP:Lanthipeptide
Region 1.3	T3PKS	1,656,405	1,697,583

No secondary metabolite regions were found in these records:: NZ_CP046630.1 (Streptococcus equinus (Streptococcus bovis))

Compact view

NZ_CP046629.1 - Region 1 - RiPP-like

Download region GenBank file

Download region SVG

Location: 410,993 - 423,817 nt. (total: 12,825 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

No tailoring functions detected.

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000619.3	0.53	ribosomal	gassericin T	Lactobacillus gasseri
BGC0001602.3	0.53	ribosomal	gassericin-T	Lactobacillus gasseri
BGC0001388.3	0.53	ribosomal	gassericin E	Lactobacillus gasseri
BGC0000624.3	0.52	ribosomal	salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide	Lactobacillus salivarius
BGC0002674.2	0.51	ribosomal	enterocin F4-9	Enterococcus faecalis
BGC0000617.5	0.50	ribosomal	coagulin	Bacillus coagulans
BGC0002579.2	0.48	ribosomal	carnobacteriocin XY	Carnobacterium maltaromaticum
BGC0002577.2	0.48	ribosomal	lactococcin G	Lactococcus lactis
BGC0000623.3	0.48	ribosomal	plantaricin W α, plantaricin W β	Lactobacillus plantarum
BGC0001862.4	0.48	ribosomal	pallidocin	Aeribacillus pallidus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000619.3	0.53	ribosomal	gassericin T	Lactobacillus gasseri
BGC0001602.3	0.53	ribosomal	gassericin-T	Lactobacillus gasseri
BGC0001388.3	0.53	ribosomal	gassericin E	Lactobacillus gasseri
BGC0000624.3	0.52	ribosomal	salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide	Lactobacillus salivarius
BGC0002674.2	0.51	ribosomal	enterocin F4-9	Enterococcus faecalis
BGC0000617.5	0.50	ribosomal	coagulin	Bacillus coagulans
BGC0002579.2	0.48	ribosomal	carnobacteriocin XY	Carnobacterium maltaromaticum
BGC0002577.2	0.48	ribosomal	lactococcin G	Lactococcus lactis
BGC0000623.3	0.48	ribosomal	plantaricin W α, plantaricin W β	Lactobacillus plantarum
BGC0001862.4	0.48	ribosomal	pallidocin	Aeribacillus pallidus

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.57 out of 18.57

Confidence: strong

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 26.79 out of 30.25

Confidence: strong

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 24.91 out of 26.06

Confidence: strong

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 22.30 out of 28.19

Confidence: medium

Additional weak hits (3):

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 22.86 out of 29.38

Confidence: weak

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 22.84 out of 29.38

Confidence: weak

HypR

Description: L-hydroxyproline utilization repressor
Species: Streptomyces coelicolor
Score: 18.94 out of 22.40

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
ColR	Phenol-responsive regulator
MogR	Repressor of flagellar motility genes
ToxT	Regulator of MSHA biosynthesis
ZuR variant 1	Zinc-responsive repressor

NZ_CP046629.1 - Region 2 - lanthipeptide-class-ii,terpene-precursor

Download region GenBank file

Download region SVG

Location: 1,121,517 - 1,154,930 nt. (total: 33,414 nt) Show pHMM detection rules used

lanthipeptide-class-ii: cds(LANC_like and DUF4135)
terpene-precursor: (PT_FPPS_like and not PT_HPP)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Lanthipeptides

Terpene

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Transferases: carbamoyltransferase

GPA00_RS05695: ornithine carbamoyltransferase

smcogs: SMCOG1114: ornithine carbamoyltransferase

Lyases: cyclase

GPA00_RS05745: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

Ligases: synthetase

GPA00_RS05800: Polyprenyl synthetase

smcogs: SMCOG1182: Polyprenyl synthetase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000547.5	0.59	ribosomal	salivaricin 9	Streptococcus salivarius
BGC0000557.5	0.56	ribosomal	streptococcin A-FF22	Streptococcus pyogenes
BGC0000532.3	0.49	ribosomal	mutacin II	Streptococcus mutans
BGC0000562.3	0.47	ribosomal	variacin	Kocuria varians
BGC0001788.3	0.47	ribosomal	suicin 65	Streptococcus suis
BGC0000521.3	0.47	ribosomal	lacticin 481	Lactococcus lactis subsp. lactis
BGC0000539.5	0.43	ribosomal	nukacin ISK-1	Staphylococcus warneri
BGC0000526.5	0.42	ribosomal	macedocin	Streptococcus macedonicus
BGC0000527.5	0.35	ribosomal	mersacidin	Bacillus sp. HIL-Y85/54728
BGC0000626.3	0.35	ribosomal	thuricin	Bacillus thuringiensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000532.3	0.78	ribosomal	mutacin II	Streptococcus mutans
BGC0000562.3	0.77	ribosomal	variacin	Kocuria varians
BGC0000547.5	0.72	ribosomal	salivaricin 9	Streptococcus salivarius
BGC0000557.5	0.70	ribosomal	streptococcin A-FF22	Streptococcus pyogenes
BGC0001788.3	0.66	ribosomal	suicin 65	Streptococcus suis
BGC0000521.3	0.63	ribosomal	lacticin 481	Lactococcus lactis subsp. lactis
BGC0000499.3	0.61	ribosomal	butyrivibriocin OR79	Butyrivibrio fibrisolvens
BGC0000526.5	0.61	ribosomal	macedocin	Streptococcus macedonicus
BGC0000539.5	0.59	ribosomal	nukacin ISK-1	Staphylococcus warneri
BGC0000527.5	0.55	ribosomal	mersacidin	Bacillus sp. HIL-Y85/54728

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Lanthipeptide predictions

Lanthipeptide(s) for GPA00_RS05745

GPA00_RS05740

Leader:

MKNTNIIDIKATEALQELSLEELDTIIGA

Core:

KKGSGVVPTVSHDCHMNSWQFLFTCCS

Core with dehydrations:

KKGDhaGVVPDhbVDhaHDCysHMNDhaWQFLFDhbCysCysDha

antiSMASH-DB 4.0 matches for GPA00_RS05740

100.0%

NZ_CP046629.1and 3 others:

NZ_FNJX01000002.1 Lanthipeptides: BLR40_RS05025_lanthipeptideNZ_FNZS01000001.1 Lanthipeptides: BMX70_RS03125_lanthipeptideNZ_FOLK01000002.1 Lanthipeptides: BM262_RS05670_lanthipeptide

Lanthipeptides: GPA00_RS05740_lanthipeptide

KKGSGVVPTVSHDCHMNSWQFLFTCCS

85.2%

NZ_CP051645.1and 2 others:

NZ_JAKVFF010000018.1 Lanthipeptides: MKR34_RS11425_lanthipeptideNZ_VDOJ01000018.1 Lanthipeptides: FSV48_RS11975_lanthipeptide

Lanthipeptides: HHJ99_RS13350_lanthipeptide

KKGSGVVPTVSHDCHMNSWQFLFTCCS

KK SGV+PTVSHDCHMNS+QF+FTCCS

KKKSGVIPTVSHDCHMNSFQFVFTCCS

81.5%

NZ_CP046304.1:

Lanthipeptides: FOC54_RS00030_lanthipeptide

KKGSGVVPTVSHDCHMNSWQFLFTCCS

KK SGV+PTVSHDCHMN++QF+FTCCS

KKKSGVIPTVSHDCHMNTFQFMFTCCS

with 73 more sequence matches

Only the first 10 are displayed here.

74.1%

NZ_CP069183.1:

Lanthipeptides: LLNCDO700_RS13730_lanthipeptide

KKGSGVVPTVSHDCHMNSWQFLFTCCS

K GSGV+ T+SH+C+MNSWQF+FTCCS

KGGSGVIHTISHECNMNSWQFVFTCCS

70.4%

NC_012470.1and 11 others:

NZ_CABY01000005.1 Lanthipeptides: SZBHS5_RS06485_lanthipeptideNZ_CP029398.1 Lanthipeptides: DF184_RS05185_lanthipeptideNZ_CP029398.1 Lanthipeptides: DF184_RS05180_lanthipeptideNZ_CP078012.1 Lanthipeptides: KV238_RS09835_lanthipeptideNZ_CP078012.1 Lanthipeptides: KV238_RS09830_lanthipeptideNZ_JAFLMI010000009.1 Lanthipeptides: J0638_RS05350_lanthipeptideNZ_JAFLMI010000009.1 Lanthipeptides: J0638_RS05345_lanthipeptideNZ_LR738724.1 Lanthipeptides: GPW69_RS05065_lanthipeptideNZ_LR738724.1 Lanthipeptides: GPW69_RS05060_lanthipeptideNZ_VZNS01000007.1 Lanthipeptides: F6P79_RS05580_lanthipeptideNZ_VZNS01000007.1 Lanthipeptides: F6P79_RS05575_lanthipeptide

Lanthipeptides: SZO_RS04070_lanthipeptide

SGVVPTVSHDCHMNSWQFLFTCCS

+GV T+SH+CHMNSWQFLFTCCS

NGVFKTISHECHMNSWQFLFTCCS

70.4%

NZ_CP026729.1:

Lanthipeptides: BKKJ1_RS07010_lanthipeptide

GSGVVPTVSHDCHMNSWQFLFTCC

G+GVV T+SH+C+MNSWQFLFTCC

GNGVVTTISHECNMNSWQFLFTCC

70.4%

NZ_GL882519.1:

Lanthipeptides: HMPREF9056_RS03330_lanthipeptide

GSGVVPTVSHDCHMNSWQFLFTCCS

G+GV T+SH+CHMNSWQF+FTCCS

GNGVYYTLSHECHMNSWQFIFTCCS

70.4%

NZ_JH792236.1and 1 other:

NZ_JH792236.1 Lanthipeptides: IIM_RS26240_lanthipeptide

Lanthipeptides: IIM_RS26245_lanthipeptide

GSGVVPTVSHDCHMNSWQFLFTCCS

GSGV+ T+SH+CHMNSWQ +FTCCS

GSGVIKTISHECHMNSWQAIFTCCS

70.4%

NZ_VDNV01000006.1:

Lanthipeptides: FSV44_RS08765_lanthipeptide

GSGVVPTVSHDCHMNSWQFLFTCCS

G GV+ T+SH+C MNSWQFLFTCCS

GGGVIQTISHECRMNSWQFLFTCCS

66.7%

NC_012470.1and 2 others:

NZ_CABY01000005.1 Lanthipeptides: SZBHS5_RS06490_lanthipeptideNZ_CP078012.1 Lanthipeptides: KV238_RS09840_lanthipeptide

Lanthipeptides: SZO_RS04065_lanthipeptide

SGVVPTVSHDCHMNSWQFLFTCCS

+G + T+SH+CHMNSWQFLFTCCS

NGAIKTISHECHMNSWQFLFTCCS

66.7%

NZ_CP023483.1:

Lanthipeptides: CNY62_RS11970_lanthipeptide

GSGVVPTVSHDCHMNSWQFLFTCCS

G+G + T+SH+CHMN+WQFLFTCCS

GNGAIRTISHECHMNTWQFLFTCCS

66.7%

NZ_CP072384.1:

Lanthipeptides: J5A65_RS01395_lanthipeptide

GSGVVPTVSHDCHMNSWQFLFTCC

G GVVPTV+H+CHMNSWQ+ F CC

GRGVVPTVTHECHMNSWQWFFGCC

66.7%

NZ_JAEEGA010000010.1:

Lanthipeptides: I6N95_RS15660_lanthipeptide

GSGVVPTVSHDCHMNSWQFLFTCCS

G+GV+ T+SH+CHMNSWQ++FTCCS

GNGVIKTISHECHMNSWQWIFTCCS

MIBiG 4.0 matches for GPA00_RS05740

14.8%

BGC0000468.5 (CCM09443.1)and 2 others:

BGC0000469.6 (AFV25481.1) Bottromycin: bottromycin A2BGC0001157.6 (CBG72694.1) Bottromycin: bottromycin A2

Bottromycin: bottromycin A2

PTVSHDC

P V DC

PVVVFDC

14.8%

BGC0000470.6 (AFU90404.1):

Bottromycin: bottromycin D

PTVSHDC

P V DC

PAVVFDC

11.1%

BGC0002111.3 (EVG22_32245)and 1 other:

BGC0002111.3 (multiple genes) Lanthipeptide: andalusicin A or andalusicin B

Lanthipeptide: andalusicin A or andalusicin B

TVSHDC

T+S++C

TISNNC

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Detailed terpene predictions

Product predictions:

Class	Subclass	Product name	Chain length	Initial cyclisations	Functional groups
sesquiterpene precursor		FPP	C15	acyclic	PP

Genes with terpene domains:

GPA00_RS05800: PT_FPPS_like

Domain 1 (25 - 271): Prenyltransferase; Farnesyl diphosphate synthase like

Subtype: Farnesyl diphosphate synthase, bacterial

Reactions:: IPP, DMAPP → FPP

Transcription Factor Binding Sites

Binding sites found:

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.57 out of 18.57

Confidence: strong

MexT

Description: Global virulence regulator
Species: Pseudomonas aeruginosa PAO1
Score: 18.79 out of 21.84

Confidence: medium

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 22.93 out of 30.25

Confidence: medium

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 23.60 out of 30.25

Confidence: medium

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 23.49 out of 27.78

Confidence: medium

LexA variant 3

Description: Repressor of DNA damage response
Species: Escherichia coli str. K-12 substr. MG1655
Score: 23.99 out of 32.93

Confidence: medium

Additional weak hits (4):

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 22.48 out of 30.25

Confidence: weak

HgtR

Description: Hydrogen-dependent regulator
Species: Geobacter sulfurreducens PCA
Score: 24.82 out of 36.54

Confidence: weak

DosR

Description: Hypoxia stress response regulator
Species: Mycobacterium tuberculosis H37Rv
Score: 19.38 out of 29.51

Confidence: weak

NuR

Description: Nickel-responsive regulator
Species: Streptomyces coelicolor
Score: 23.65 out of 30.98

Confidence: weak

Lanthipeptides

Terpene

TFBS Finder

Core peptide predictions

GPA00_RS05740 - Class II

Cleavage pHMM score: 5.40

RODEO score: 0

Monoisotopic mass: 2889.3 Da

Molecular weight: 2891.3 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 2909.3 Da N = 1; 2927.3 Da N = 2; 2945.4 Da N = 3

Glossary

Acronym	Full name
DMAPP	Dimethylallyl diphosphate
FPP	Farnesyl diphosphate
IPP	Isopentenyl diphosphate
PP	Diphosphate

TFBS definitions

Regulator	Description
CodY	Regulator of stationary phase and virulence in Gram-positive bacteria
ColR	Phenol-responsive regulator
LexA variant 3	Repressor of DNA damage response
MexT	Global virulence regulator
ToxT	Regulator of MSHA biosynthesis

NZ_CP046629.1 - Region 3 - T3PKS

Download region GenBank file

Download region SVG

Location: 1,656,405 - 1,697,583 nt. (total: 41,179 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

NRPS/PKS domains

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: oxidoreductase reductase

GPA00_RS08275: hydroxymethylglutaryl-CoA reductase

smcogs: SMCOG1187: hydroxymethylglutaryl-CoA reductase

GPA00_RS08365: aldo/keto reductase family oxidoreductase

smcogs: SMCOG1039: aldo/keto reductase family oxidoreductase

Isomerases: isomerase

GPA00_RS08185: isochorismate synthase

smcogs: SMCOG1018: isochorismate synthase

Ligases: synthase

GPA00_RS08270: hydroxymethylglutaryl-CoA synthase

smcogs: SMCOG1043: hydroxymethylglutaryl-CoA synthase

Translocases: permease

GPA00_RS08240: phenylalanine-specific permease

smcogs: SMCOG1038: phenylalanine-specific permease

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002561.3	0.45	other (other)	phenazine SA, phenazine SB, phenazine SC	Streptomyces sp.
BGC0000016.4	0.44	other (other)	amphotericin B	Streptomyces nodosus
BGC0000883.5	0.43	other (other)	arginomycin	Streptomyces arginensis
BGC0002707.2	0.41	terpene	(+)-δ-cadinol	Coniophora puteana RWD-64-598 SS2
BGC0000513.3	0.41	ribosomal	Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3	Saccharopolyspora erythraea NRRL 2338
BGC0002031.3	0.41	other (other)	kitasetaline	Kitasatospora setae KM-6054
BGC0001080.5	0.41	other (phenazine)	endophenazine A, endophenazine B	Streptomyces anulatus
BGC0000934.4	0.41	other (phenazine)	5-acetyl-5,10-dihydrophenazine-1-carboxylic acid, 5-(2-hydroxyacetyl)-5,10-dihydrophenazine-1-carboxylic acid, endophenazine A1, endophenazine F, endophenazine G	Kitasatospora sp. HKI 714
BGC0000286.3	0.40	PKS	viguiepinol	Streptomyces sp. KO-3988
BGC0002260.3	0.40	terpene	trichobrasilenol, xylarenic acid B, brasilane A, brasilane F, brasilane E, brasilane D	Annulohypoxylon truncatum

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002561.3	0.45	other (other)	phenazine SA, phenazine SB, phenazine SC	Streptomyces sp.
BGC0000016.4	0.44	other (other)	amphotericin B	Streptomyces nodosus
BGC0000883.5	0.43	other (other)	arginomycin	Streptomyces arginensis
BGC0002707.2	0.41	terpene	(+)-δ-cadinol	Coniophora puteana RWD-64-598 SS2
BGC0000513.3	0.41	ribosomal	Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3	Saccharopolyspora erythraea NRRL 2338
BGC0002031.3	0.41	other (other)	kitasetaline	Kitasatospora setae KM-6054
BGC0001080.5	0.41	other (phenazine)	endophenazine A, endophenazine B	Streptomyces anulatus
BGC0000934.4	0.41	other (phenazine)	5-acetyl-5,10-dihydrophenazine-1-carboxylic acid, 5-(2-hydroxyacetyl)-5,10-dihydrophenazine-1-carboxylic acid, endophenazine A1, endophenazine F, endophenazine G	Kitasatospora sp. HKI 714
BGC0000286.3	0.40	PKS	viguiepinol	Streptomyces sp. KO-3988
BGC0002260.3	0.40	terpene	trichobrasilenol, xylarenic acid B, brasilane A, brasilane F, brasilane E, brasilane D	Annulohypoxylon truncatum

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.57 out of 18.57

Confidence: strong

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 23.58 out of 27.78

Confidence: medium

CcpA

Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 18.98 out of 20.97

Confidence: strong

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.73 out of 26.06

Confidence: medium

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 23.60 out of 30.25

Confidence: medium

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 24.62 out of 27.78

Confidence: strong

ArcA

Description: Repressor of carbon oxidation
Species: Escherichia coli str. K-12 substr. MG1655
Score: 19.05 out of 21.55

Confidence: medium

ArcA

Description: Repressor of carbon oxidation
Species: Escherichia coli str. K-12 substr. MG1655
Score: 19.76 out of 21.55

Confidence: medium

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 24.52 out of 28.19

Confidence: strong

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 23.18 out of 28.19

Confidence: medium

Additional weak hits (6):

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 22.41 out of 30.25

Confidence: weak

LuxO

Description: Repressor of luminescence
Species: Vibrio campbellii ATCC BAA-1116
Score: 20.68 out of 26.12

Confidence: weak

NrtR

Description: NAD synthesis repressor
Species: Streptomyces coelicolor
Score: 23.74 out of 35.63

Confidence: weak

RutR

Description: Regulator of the pyrimidine and purine metabolism
Species: Escherichia coli str. K-12 substr. MG1655
Score: 20.83 out of 26.85

Confidence: weak

NrtR

Description: NAD synthesis repressor
Species: Streptomyces coelicolor
Score: 23.89 out of 35.63

Confidence: weak

RicR

Description: Copper-responsive regulator
Species: Mycobacterium tuberculosis H37Rv
Score: 21.87 out of 32.93

Confidence: weak

Detailed domain annotation

Selected features only

Show module domains

TFBS Finder

TFBS definitions

Regulator	Description
ArcA	Repressor of carbon oxidation
CcpA	Catabolite control protein A
CodY	Regulator of stationary phase and virulence in Gram-positive bacteria
ColR	Phenol-responsive regulator
MogR	Repressor of flagellar motility genes
ToxT	Regulator of MSHA biosynthesis
ZuR variant 1	Zinc-responsive repressor