LOCUS       NZ_WHOM01000070        22772 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Streptomyces apocyni strain TRM 66233 513, whole genome shotgun
            sequence.
ACCESSION   NZ_WHOM01000070
VERSION     NZ_WHOM01000070.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces apocyni
  ORGANISM  Streptomyces apocyni
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 52450)
  AUTHORS   Liu,W.
  TITLE     Streptomyces poacynumensis sp. nov., a endogenous actinomycete
            isolated from Poacynum hendersonii
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 52450)
  AUTHORS   Liu,W.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-OCT-2019) Key Laboratory of Protection and Utilization
            of Biological Resources in Tarim Basin of Xinjiang Production &
            Construction Corps, Tarim University, Xingfu Road, Alar, Xinjiang
            843300, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: ABySS v. 2.2.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009739465.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 17:09:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,397
            CDSs (total)                      :: 6,319
            Genes (coding)                    :: 6,205
            CDSs (with protein)               :: 6,205
            Genes (RNA)                       :: 78
            rRNAs                             :: 6, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 34 of 114
            Pseudo Genes (incomplete)         :: 100 of 114
            Pseudo Genes (internal stop)      :: 6 of 114
            Pseudo Genes (multiple problems)  :: 23 of 114
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:56:55
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4794
            Orig. end                         :: 27566
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            WHOM01000070.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22772
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22772
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22772
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:12772](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12772
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            complement(1073..1807)
                     /locus_tag="GCN81_RS25105"
     CDS             complement(1073..1807)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018511742.1"
                     /locus_tag="GCN81_RS25105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SCO2322 family protein"
                     /protein_id="WP_156726766.1"
                     /transl_table=11
                     /translation="MRHAHVGPRRLALGAVLVSLLGALLAALCAAAVPAQAAGYRYWSF
                     WDLDGEKWTYAQQGPSSTRPSDGDVQGFRFSVSEDSQDSAKPRTTAGSGAGVAEFASIC
                     ADTPERDGRKRVALVIDFGTAQDAPQGETPPKPRTVCARVAPDATTAEALAEVAKPLRY
                     DSSAMLCAIAGYPKTGCGEQVSSDGDSDGDSDEAAPPAPDTSDDATGDTSGDGPSAGLI
                     AGLAAVFALGAAAVWQARRRRG"
     gene            complement(1810..3066)
                     /locus_tag="GCN81_RS25110"
     CDS             complement(1810..3066)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003976492.1"
                     /locus_tag="GCN81_RS25110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_156726767.1"
                     /transl_table=11
                     /translation="MNVRRSAAALAATAVLCAAAAPAAVADDSPSPSAPSAPVSLPSGL
                     YGDADPQYDGVFRQSYALLAQDTAGVKPAAKAVEWLTRQQCASGGFAAFRADPTEPCDS
                     KTEFALDSTAAAIQALNAVGGQDAAKAQKKATDWLKSVQNDDGGWGYTTGADSDVNTTG
                     MVIGALAASDTKPESVTSPKDKSPYDALLALSLDCDKGDGAFGLADFKTGELDANPLAT
                     AAGVLGALGEGLGAKPGEQRAAAPKCAKADTAEQAAVNGAGYLTDALAKDGYLTAATPG
                     ADAQPDYGTTADAVAALGAAGLGDQAKDSVAWLEKNAASWAEEKGPAAYAKLIFAARAT
                     GGDARDFGGTDLVSALNKTGPAPQADGTSDKSDESKTASDSSDSDSDSVAVWWIIGVGL
                     VAGVGIGFLISARNKKKQQ"
     gene            complement(3353..3886)
                     /locus_tag="GCN81_RS25115"
     CDS             complement(3353..3886)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010047898.1"
                     /locus_tag="GCN81_RS25115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NUDIX hydrolase"
                     /protein_id="WP_156726768.1"
                     /transl_table=11
                     /translation="MSEHGELVERVDERDRVIGIVDRGEAIRRGWLHRVATAVCRDAGG
                     RDDAGGRILVHRRPDGVSRFPGQYNFMVGGAVDVGESYAQGAVREIEEELGVRVPVRHG
                     VTFLCRGAISPYWLGVHEAVVRPSEIRPDPAEFAWHGWWSEDELRGAMTRLPFVPDAVE
                     AYARLRASRCSTGR"
     misc_feature    complement(3876..3891)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.08"
                     /tool="antismash"
     gene            4026..6296
                     /locus_tag="GCN81_RS25120"
     CDS             4026..6296
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013124.5"
                     /locus_tag="GCN81_RS25120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NB-ARC domain-containing protein"
                     /protein_id="WP_156726769.1"
                     /transl_table=11
                     /translation="MPGKTAQPHNGQPGNLPPETTSFVGRGRELDMLKVVLTGGPRDTP
                     GFGGRLVTLTGAGGVGKTRLALRAAARARTAYPDGVWLTELSPLRNADQVALTLTRTLR
                     LITDQSARPVGETLVDWLEDKRLLLVLDSCEHLVSGCARTLLPLLAGAPGVCVLATSRQ
                     PIGIDGERRIDVDPLPVTDTEHTAAATLFAQRAGAAAPGFRLDDTNRETVLGICRRLDG
                     VPLAIELAAAQLPELSVGSLYERLGERLPSRLDLLTTRSVRDHRDYGGDHCDHHADHGD
                     CRLRDDRDDRDERGLPRHQALRTTIGWSHELCEPLERLLWARLSVFAGTFGVEAAERVC
                     AGGPLPAHRVVGLLARLLDKSIVRHDQRDRGRLRMLDTVREYGTDWLRRLGDVHRMRLR
                     HLDFYRDLARRGCAEWNTARQVMWCDRIVAEHSNLRAAVDFALAEPDTSVALDITAHAG
                     FLWRHCGYGRDAAACLDQVLTVDAEPGPVRTLALWSRGSVAILQGDLDVAEVWADLTAQ
                     AAAEQGDARVVAAARYLAGSAPLLRGRLEEAIEAYGSCGLYGPSGLSGLSDSSGPFGSY
                     GFFESSDWCGSAMLQARCGITLAHLLAGRFDQAGEVGEALWRDCVRIGERWVRAWTEPM
                     LAQVALAAGDTAEAERRAREGVVGHELLHNTAGVGHALDALAEAVLARGDAARAAVLLG
                     VSDRFWSLAGRPQLDSAEMRAARRASEDRARRAIGGEEYEKEYRAGQEMTYEDGVAYAT
                     ARW"
     misc_feature    5721..5723
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(6317..7381)
                     /locus_tag="GCN81_RS25125"
     CDS             complement(6317..7381)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170: metallo-beta-lactamase family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010070569.1"
                     /locus_tag="GCN81_RS25125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_156726770.1"
                     /transl_table=11
                     /translation="MSPTTTGTTTRVTEHGGGVWSIKVPIPDNPLGHTLVHLLDTDRGP
                     VLIDTGWDDPESYDTLVAGLAACGVAIGELHGVVITHHHPDHHGLSGKVREASGAWIAM
                     HPADAHVVRRTREQRPERWIDYLTDKLAAAGAPADHLAPLLAARESGRMRTLPGLHAAL
                     PDRDITPGELLDLPGRRLRAIWTPGHTPGHVCLHLEEEHPAGKPGLGRLFSGDHLLPGI
                     TPHIGLYEDPEESAVTDPLGDYLASLERVGRLGVSEVLPAHQYAFTDAPGRVRELLDHH
                     DERLRGLRALLASPLTPWQLAVRMEWNRPWADIPYGSRNIAVSEAEAHLRRLVKLGHAE
                     AVPGSDPVAYRAVA"
     misc_feature    7390..7403
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.91"
                     /tool="antismash"
     misc_feature    7396..7409
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.68"
                     /tool="antismash"
     gene            7481..8065
                     /locus_tag="GCN81_RS25130"
     CDS             7481..8065
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018520541.1"
                     /locus_tag="GCN81_RS25130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_156726771.1"
                     /transl_table=11
                     /translation="MRDHLEAPSGLVLRQWAAVDARAVLAAFADPLMREQSAEPLDSLS
                     AAERWIAERQDEWSAGTAYAFAVTDGSGGGNGGAVLGQMSIGGVHRRHRIGWVSYWTTA
                     AARGRGVASRACRVAAEWAFTDAGLFRLELGHRVNNPASCAVARAAGFAVEGRQRQKLE
                     YDGVRYDVELHARLATDPGPVNGAHTVDSSN"
     gene            8142..9602
                     /locus_tag="GCN81_RS25135"
     CDS             8142..9602
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004001637.1"
                     /locus_tag="GCN81_RS25135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aldehyde dehydrogenase"
                     /protein_id="WP_156726772.1"
                     /sec_met_domain="Aldedh (E-value: 5.1e-152, bitscore:
                     498.1, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTELVEHRKLFIGGELVDPLGQGVIEVISPHTEQVIGRVPHAAP
                     ADVDRAVALARRAFDEGPWPRMTLDERIAVVTRIKDAFAVRHEEIARVISSENGTPYTS
                     SVMVQSLASMMVWEAALATARDFTYEERRDGILGKILVRREPVGVVAAVVPWNVPQFTA
                     AAKLAPALLAGCPVILKVSPETPLDAYLLAEIATEAGLPEGVLSIIPADREVSEYLVAH
                     PGVDKVSFTGSVGAGKRVMEVCSRNLTRVTLELGGKSAAVILPDADAATAVAGIVPFAW
                     MINGQACVAQTRILVPRGRYDEFAEAFATAAGALKVGDPLDPATELGPLVAKRQQQRSL
                     DYIRIGQEEGAKILTGGGRPAGLDQGWYVEPTLFGGVDNSMRIAREEIFGPVICLLPYG
                     DEAEAVKIANDSDYGLSGSVWTADVERGIDVARRVRTGTYSVNTFSLDMLGPFGGYKNS
                     GLGREFGPEGYGEYFEHKMIHLPGGYEG"
     gene            9613..9846
                     /locus_tag="GCN81_RS25140"
     CDS             9613..9846
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1265: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004001638.1"
                     /locus_tag="GCN81_RS25140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ferredoxin"
                     /protein_id="WP_156726773.1"
                     /transl_table=11
                     /translation="MGDRWQVEVDRGVCIGSGMCVNHAPDGFRLDTARQSHPVDAETDA
                     NEKVLEAAEGCPVEAITITLLATGEAVFPPDE"
     gene            10001..12772
                     /gene="lanKC"
                     /locus_tag="GCN81_RS25145"
     CDS             10001..12772
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010354516.1"
                     /locus_tag="GCN81_RS25145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_156726774.1"
                     /sec_met_domain="micKC (E-value: 2.6e-223, bitscore: 735.1,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 1.6e-11, bitscore: 35.6,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKRYEVYALADRFFYETPNRVSSTGTSATTTGTTGATALYETAR
                     RPVPDGWRTQRTGDWLVFAPVDDTGHPLTAPSQGWKIHVSATGENAEKTAAVVADYCLP
                     RGIPFKFVPGARLLHLRNSKYAPRDGSGKFATLYPADGYQLRTTLTELGGQLDGFDGPY
                     VLTDLRWHNGPLYVRYGAFARRFCLDGRGTLVPAIENAAGDLVPDPRDPAFQVPEWVKL
                     PGFLEPHLAARNATTVSDLPYRIEKALHFSNGGGVYAGTDTRDASRVVLKEGRPHAGLA
                     ADGADAVARLEREKAALERLSGLGVAPEARDWFTLGDHRFLVMDFLPGRTLNSFLAERH
                     PLCTCDPDPAAIADYTDWALGIHRAVEEAVAAVHGRGVVFNDLHLFNIMVAPDERSVAL
                     LDFEAATTVGDSGRQVVAHPGFMAPAGRTGTDIDRYALACLRIALFLPITSLFAIDRGK
                     AAHLAEVAAGLFPGIPDGFLDEAVTEITRDGDRAPVPQGGGSGATSTITAGAGPGGGAG
                     AGAEAGGSARWVALAETGDWPRSRDSMVAAILASATPDRDDRLFPGDIAQFSEGGGLGL
                     AYGAAGVLHALAETGAERYEQGERWLLAHTDPVPAGTPLGLYDGLAGVAYVLDRLGHRQ
                     RALDLADQILREPWQRLTPDLHSGLAGLGLVLDALAHTTGESALRGPALRAAELVGDRL
                     TAAEPGPPASRRAGLLRGSTGAALLFLRLHERTQDPDLLDQAARALRADLGACVSQPDG
                     SLAVDEGWRTMPYLGEGSVGIGMVIDDYLARSARPAQSARSSDEEFTRARTDILAAARS
                     GFYAQPGLFRGRAGMVLHLSRSTATPETAAALAAQIAGLGWYAMPYAGQLAFPGDQMMR
                     LSMDLGTGTAGCLLALGAALGDTGAHLPFLPPPPPPPLWPSSRLRDTSSTES"
     gene            12822..12935
                     /locus_tag="GCN81_RS25150"
     CDS             12822..12935
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018849360.1"
                     /locus_tag="GCN81_RS25150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_156726775.1"
                     /transl_table=11
                     /translation="MALLDLQNMETELTGGGDVSYASLLLCGDSGLSVLTC"
     CDS_motif       12822..12875
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MALLDLQNMETELTGGGD"
                     /locus_tag="GCN81_RS25150_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12876..12935
                     /prepeptide="core"
                     /locus_tag="GCN81_RS25150_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="14.90"
                     /molecular_weight="1811.1"
                     /monoisotopic_mass="1809.9"
                     /core_sequence="VSYASLLLCGDSGLSVLTC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MALLDLQNMETELTGGGD"
                     /leader_location="[12821:12875](+)"
                     /alternative_weights="1829.1"
                     /alternative_weights="1847.1"
                     /alternative_weights="1865.2"
     gene            complement(12981..13595)
                     /locus_tag="GCN81_RS25155"
     CDS             complement(12981..13595)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010354522.1"
                     /locus_tag="GCN81_RS25155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_156726776.1"
                     /transl_table=11
                     /translation="MIRVLLVHDSRLLRSALAERLARETDLEVWHTSWDGAPTRMRTLR
                     PDLCVADLDCDAVYAVPPLGKLAACAATARPGGCSLLVLGGPGRPGPLRRAAEVDALGY
                     VDKASPPERLLTAIRQVARGERFIDASLGFGFLKASQMPLTRRELSVLSLAAEGASVAE
                     IADRLHLSNGTVRNYMAAITRKTGARNRVDAIRISQGEGWV"
     gene            complement(13964..14644)
                     /locus_tag="GCN81_RS25160"
     CDS             complement(13964..14644)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007263850.1"
                     /locus_tag="GCN81_RS25160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_156726777.1"
                     /transl_table=11
                     /translation="MTTEAKESGIASAPLTERQEARRRRILHASAQLASKGGFDAVQMR
                     EVAESSSVALGTLYRYFPSKVHLLVATMQDQLQHMHGTLRKHPPAGDTAAERVAETLMR
                     AFRALQREPHLADAMVRALTFADRSVSPEVDTVSRLTTAIILDAMGLEHPTPQQLSAVR
                     VIEHTWHSALITWLSGRASIAQVKIDIETVCRLIDLTSPGTTGATGTTGTPRGGAGRGL
                     GAGA"
     misc_feature    complement(14797..14810)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.98"
                     /tool="antismash"
     misc_feature    14803..14819
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.82"
                     /tool="antismash"
     gene            14879..16213
                     /locus_tag="GCN81_RS25165"
     CDS             14879..16213
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019885936.1"
                     /locus_tag="GCN81_RS25165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_156726805.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 3e-32, bitscore:
                     103.2, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERHPLRIALLTYKGNPFCGGQGVYVRHLSRELTRLGHHVEVIGA
                     QPYPVLDEGVPLTELPSLDLYRSPDPFRTPKRSEFRGWIDALEFATMRTGGFPEPLTFS
                     LRARRHLAARRGEFDVVHDNQTLGYGLLGGPERLGAPLVTTIHHPITVDRQLELDAAAD
                     WKGRASVRRWYGFTRMQKRVARRLPSVLTVSGSSRQEIVDHLGVRDDRVHVVHIGADTD
                     LFSPDPAIPEVPGRIVTTSSADVPLKGLIHLIEALAKVRTENPAAHLVVVGKRAEDGPV
                     AGAIERYGLQNAVEFVKGITDAELVDLVRGAQIACVPSLYEGFSLPAAEAMATGTPLLA
                     TTGGAIPEVAGPDGETCLAVPPGDAGALAAGLTRLLGDRELRARLGAAGRERVLARFTW
                     ARAAEGTAERYREAIARSAGTARVAGSTTGRSAAIRTDTPLGSAH"
     gene            16213..16980
                     /locus_tag="GCN81_RS25170"
     CDS             16213..16980
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005478650.1"
                     /locus_tag="GCN81_RS25170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_156726778.1"
                     /transl_table=11
                     /translation="MLTVDFSRFPLAAGDRVLDLGCGAGRHAFECYRRGARVVALDQNA
                     EEIREVAKWFAAMKEAGEAPEGATATAMEGDALALPFPDASFDVVIISEVMEHIPDDKG
                     VLAEMVRVLRPGGRIAVTVPRHGPEKVCWALSDAYHEVEGGHIRIYKADELLGKMREAG
                     LKPYGTHHAHALHSPYWWLKCAFGVDNDKALPVRAYHKLLVWDIMKKPLATKIAEQALN
                     PLIGKSFVAYATKPHLPTDVVADLATDTAAAAK"
     gene            16977..18104
                     /locus_tag="GCN81_RS25175"
     CDS             16977..18104
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010987259.1"
                     /locus_tag="GCN81_RS25175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="prenyltransferase"
                     /protein_id="WP_156726779.1"
                     /transl_table=11
                     /translation="MTTPTPQTEHLVLPGVLTAEQAAHTVRGILAGQREDGAIPWFRGH
                     HLDPWDHTEAAMALDAAGEHAAAARAYDWLARHQNPDGSWYAAYDDGDATRPTDRSVES
                     NFSAYIAVGAWHHYLSTGDDAFLDAIWPHVYAAIECVLTLQQPGGQIGWKREAAEEGGA
                     AEEGVAGDERVAGAPVTDALLTGSSSIHQALRCALAIAEQREEPQPDWELALGALGHAI
                     RRHPERFLDKNRYSMDWYYPVLGGAITGPEAKARIEESWDRFVVPEFGVRCVVPNPWVT
                     GGESAELALTLWAMGESDRALSILQSIGHLRDEETGLYWTGYVYDDQAVWPVEQTTWTA
                     GALLLAVAALGGDEATCAIFDGGRLPRGLTPDCCD"
     gene            complement(18138..19148)
                     /locus_tag="GCN81_RS25180"
     CDS             complement(18138..19148)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605923.1"
                     /locus_tag="GCN81_RS25180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LLM class F420-dependent oxidoreductase"
                     /protein_id="WP_156726780.1"
                     /transl_table=11
                     /translation="MRLGLALGYWGRGPGTEHVQLAQEAERLGYDSVWTAEAWGSDVFT
                     PLTWIAAQTSRIRLGTAIAQMAARTPTATAMHALTLDHLSGGRMLLGLGLSGPQVVEGW
                     YGRPFPRSPLTATREYVDVIRQVLRREGPVTLDGQFHGLPYDGADGTGLGKPLKPITHP
                     LRAELPILLGAEGPRNIAQTTRIADGWLPLYWSPTRTDVYEASLTGLRDGFMVAPMVRA
                     HVCDDVAEGLLPVKAMLGFYIGGMGHTSRNFHADLMARMGFEDAARRIQQLFAEGRREE
                     AVRAVPDAFADEISLVGPRERIAERLELWRKGPVTDLLVMSPDAHTLRVLAELNT"
     gene            complement(19297..20109)
                     /locus_tag="GCN81_RS25185"
     CDS             complement(19297..20109)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018103419.1"
                     /locus_tag="GCN81_RS25185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_407698021.1"
                     /transl_table=11
                     /translation="MVIGAAVLLFIASFLDLYSVSGATGDLDLPNSWDSLGNGIGVYMA
                     GVIGAVLIVVNRCLPQPRKVIGLDLGQVGIAFTILVAWNFFWTIIDVSDNVDAGAGLIL
                     GLISALLLAGAAISSPLVPALSAPLMGATPAPMMGQQPYGGQPGMPQQGGYGYPGAQQQ
                     PYGGQPQPGQPQPSYGGQPGQPQAQQASEQAQQPQAQQAPAADFAPFWFAVPVARPLYA
                     EDGSPTPIAELAPGTWYLAVEQRGPGLVAQTQDGRRGVLQDTTGIQRG"
     gene            complement(20308..21351)
                     /locus_tag="GCN81_RS25190"
     CDS             complement(20308..21351)
                     /EC_number="3.5.1.28"
                     /GO_function="GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA]"
                     /GO_process="GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016326100.1"
                     /locus_tag="GCN81_RS25190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_156726782.1"
                     /transl_table=11
                     /translation="MSYDDPDSPSPAPRRPLSRGRALVVAAALVPVGLGGWLLWQGVSG
                     AQDSGGSDAGKGETATATATPSGSGSAADSPSAEPSGTDGPSSGKPSGDASTSSSTPSP
                     SPKPSTSPSPSPSGTTPRTGPLKGKVVVIDPGHNPRNRDHPTQIARQVDVGTHRKECDT
                     TGTATNAGYSEAAFNLDLAHRLRKLLEEQGATVKLTQDNDRPYGPCIDERARIGNEAKA
                     DAVVSLHADGSSAGNRGFHVILPGKVKAGAADTSAIVAPSRELGERIAGGFVRRTGNAP
                     SNYIGGGTGLDVRKDLGGLNLSKVPKVFIECGNMRDADDAAQLTNGTWRQKAARGISEG
                     IAGFLKG"
     gene            complement(21469..22056)
                     /locus_tag="GCN81_RS25195"
     CDS             complement(21469..22056)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019067188.1"
                     /locus_tag="GCN81_RS25195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_231626962.1"
                     /transl_table=11
                     /translation="MPLGEGLALYAAAVEAGRLGLPLLEVGTYCGRSTVLLADAAREAG
                     TTAVTVDHHRGSEEQQPGWEYHDPTVVDAEVGLMDTLPTFRRTLHRAGLEEHVIAVVGR
                     SPQVAKVWGGPLGLVFIDGGHTDEHATGDYEGWAPHLAEGGLLVIHDVFPNPADGGQAP
                     YRVYRRALESGAFAEVSVTDSLRVLRRTGAGI"
ORIGIN
        1 atcaccccgg gacgcaggcc cacggggtcg tacgacgcgg cccagatcat cagccccgcc
       61 acggccaccc cggaccccga caccagccag gcgcgcgccg cccaacggtc aggccggtac
      121 cgggtacgga cgcaccgccg ccccccgagc cacagcccac cgagcgccgc gccgagcccg
      181 cccagcagta ccggcagccc gaaccccgcg ccctcagcgg cgagcagccc gtacgttccc
      241 gcgcagacgc cgagcagccc gccgagcgtg agggccgccg tggtgcgccg taccgccacg
      301 ggcacatgcg cggtacgccc gtacccccgc gcgtccatcg ccgcggcaag ggcgaccgac
      361 cgctccaggg cgccttccag gaccggcagc ccgacctgga gcagcccccg cacaccacgg
      421 tcgggacggc cgcgcagccg ccgcgccttc cgcagccgct gtacgtccgc gatcagctgc
      481 ggcgcgaagg tcatcgccac cacgaccgcg acccccgcct cgtacagcgc gcccggcagg
      541 gacttcagca gccgcaccgg gttggcgagt gcattcgccg cgcccacgca gatcagcagg
      601 gtggccagct tcagcccttc gtacagcgcg aacagcaggc tctccgcgct gacccggccg
      661 ccgatccgaa ctcccttcgc ccactccggc agcggcacct cgggcagcgt gaacaggacg
      721 tgtgtgccgg ggatcggcga gccgaggaag accgcgaacc cgagcctgat cgcgatcacg
      781 gcgagcccca gcttgacgaa ggccccatag ctgcgcgccc acggcgcgtc cgtacggcgc
      841 accgcgacca catatcccgc gaccgcgatc agcagcccga gcagcaacgg gttggtcgtc
      901 cgcgacgccg cggtggccag gcccagcgcc cacacccacc aggcaccgga gtgcagcgcg
      961 tcactccgcc gcccggcctc aggagcgacc aggcccgccc gcgcggcggc gacggctccc
     1021 ctcgccccct tcgccccgcg cacggccccg cccctatgcc tcatgttcag cgtcagccgc
     1081 ggcgacggcg ggcctgccag acggcggccg caccgagggc gaagaccgcg gcgaggcccg
     1141 cgatcagacc tgcggagggg ccgtcgccgg acgtgtcgcc ggtggcgtcg tcggaggtgt
     1201 cgggtgccgg gggcgcggcc tcgtcgctgt cgccatcgct gtcgccatcg ctggagacct
     1261 gctcgccgca gcccgtcttc gggtaccccg cgatcgcgca gagcatcgcg ctgctgtcgt
     1321 accgcagcgg cttggcgacc tccgcgagtg cctccgccgt ggtcgcgtcg ggggcgaccc
     1381 gcgcgcagac cgtacgcggc ttcggcggcg tctcgccctg cggcgcgtcc tgtgccgtac
     1441 cgaagtcgat gaccagcgcc acccgcttac ggccgtcccg ctcaggggtg tccgcgcaga
     1501 tcgacgcgaa ttcagccacg cccgcgcctg agcccgccgt ggtgcgcggc ttcgccgagt
     1561 cctgcgagtc ctcgctcacc gagaaccgga agccctgcac gtccccgtcc gatgggcggg
     1621 tggacgacgg accctgctgg gcgtacgtcc acttctcacc gtccaggtcc cagaaggacc
     1681 agtaccggta tccggccgcc tgcgccggaa cggcggccgc gcagagcgcg gcgagcaggg
     1741 cgccgagcag gctgaccagt acggcgccga gcgcgagacg gcgaggccca acgtgggcgt
     1801 ggcgcacgac tactgctgct tcttcttgtt acgggcgctg atcaggaagc cgatgccgac
     1861 acccgcgacc agcccgacgc cgatgatcca ccagacggcg acggagtcag agtcggagtc
     1921 gctggagtcc gaggcggtct tggactcgtc ggacttgtca gacgtgccgt ccgcctgggg
     1981 cgcggggccc gtcttgttca gggcgctgac caggtccgta ccgccgaagt cgcgcgcgtc
     2041 gccgcccgtc gcccgcgcgg cgaagatcag cttggcgtag gcggccggac ccttctcctc
     2101 ggcccaggag gcggcgttct tctccagcca ggccaccgag tccttcgcct ggtcgccgag
     2161 ccccgccgcg ccgagcgccg cgacggcgtc cgccgtggtg ccgtagtcgg gctgcgcgtc
     2221 ggcgcccggc gtggcggccg tcaggtagcc gtccttggcg agcgcgtcgg tcaggtaccc
     2281 ggcgccgttc acagccgcct gttccgcggt gtccgccttc gcgcacttcg gcgcggcggc
     2341 gcgctgctcg cccggcttcg caccgaggcc ctcgccgagc gcgccgagca caccggcggc
     2401 ggtggcgagc ggattggcgt ccagctcacc ggtcttgaag tccgcgaggc cgaacgcgcc
     2461 gtcgcccttg tcgcagtcga gggagagcgc gagcagcgcg tcgtacggcg acttgtcctt
     2521 cggcgaggtc accgactccg gcttcgtgtc cgaggcggcc agcgcgccga tcaccatgcc
     2581 ggtggtgttg acgtcactgt cggcgcccgt ggtgtagccc cagccgccgt cgtcgttctg
     2641 tacggacttg agccagtctg tcgccttctt ctgggccttg gcggcgtcct gcccgccgac
     2701 cgcgttcagc gcctggatgg cggcggccgt cgagtcgagc gcgaactccg tcttggagtc
     2761 gcacggctcg gtcgggtcgg cccggaacgc cgcgaagccg ccgctggcgc actgctgccg
     2821 ggtcagccac tcgacggcct tggcggcggg cttgaccccg gcggtgtcct gcgcgagcag
     2881 cgcgtacgac tgccggaaga cgccgtcgta ctgcgggtcc gcgtcgccgt acaggcccga
     2941 ggggaggctt acgggcgccg agggtgccga gggtgacggg gaatcgtcgg cgacggcggc
     3001 cggggcggcg gccgcgcaga gtacggcggt ggcggccagg gctgcggcgc tgcggcgaac
     3061 gttcatgcgg gcggatgcct ctcctgcggg gaaccgggca cgggcccgcg aaggcaccgg
     3121 gctccggctc cgtatacctc gacggtgccg gtcgccgggg tccggcgacg ggagccacgc
     3181 acgcctggcg gggcgttccg gctcaccgcc gggtatggcg gcatacgaat ggggtctccc
     3241 ctgttcgagc gaagtcgaga acttggggaa gggtcagcgc cggaatcgca ccggcttccc
     3301 cccgtacggg cgtggtgatg acctgcccac tctaccggcc ggtcgaagct cgttaccggc
     3361 cggtcgaaca gcgactcgcc cggagccgcg cgtacgcctc caccgcgtcc ggcacgaaag
     3421 gcagccgcgt catcgccccg cgcagctcgt cctcgctcca ccacccgtgc cacgcgaact
     3481 ccgccggatc gggcctgatc tccgacggcc ttacgacggc ctcgtgcacc cccagccagt
     3541 acgggctgat cgcgccccgg cagaggaagg tgaccccatg ccgcaccgga acccgtaccc
     3601 ccagctcctc ctcgatctcg cggaccgccc cctgtgcgta cgactcaccc acgtccaccg
     3661 ccccgccgac catgaagttg tactgacccg ggaaccggga caccccgtcc gggcgccggt
     3721 gcaccagaat ccggcctccg gcgtcatccc ggcctccggc gtcgcggcag acggcggtcg
     3781 cgacccggtg gagccagccg cgccggatgg cctcgccccg gtccacgatc ccgatcaccc
     3841 ggtcccgctc gtccacccgc tctaccagtt caccgtgttc gctcatgggg cggacgatgc
     3901 cagagtcacc cgtaaggctc tctggcggct gatcacctac gcgggcagac tgggagacgc
     3961 ctacggtgtg gccgagcagc ggagaggctc aggggtggga gcgggagtgg gaggggcaag
     4021 ggccaatgcc ggggaagaca gcgcaaccac acaacgggca gccgggcaac ctgcccccgg
     4081 agaccaccag cttcgtcggc cgcgggcgtg agctcgacat gctcaaggtg gtgctcaccg
     4141 gtggcccccg cgacaccccc ggcttcggcg gccgcctcgt caccctcacc ggcgcgggcg
     4201 gcgtcggcaa gacccggctc gcgctgcgcg ccgccgcgcg cgcccgcacc gcctacccgg
     4261 acggggtgtg gctcacggag ctgtccccgc tgcggaacgc ggaccaggtg gcccttaccc
     4321 tcacccggac cctgcggctg atcaccgacc agtccgcccg cccggtcggc gagacactcg
     4381 tcgactggct tgaggacaaa cggctgctgc tggtcctgga ctcctgcgag cacctggtgt
     4441 ccggctgcgc gcgcaccctg ctgcccctgc tcgccggggc gccgggcgtc tgcgtcctgg
     4501 ccaccagccg acagcccata gggatcgacg gcgagcggcg catcgacgtc gacccgctgc
     4561 ccgtcaccga caccgaacac accgccgcgg ccaccctctt cgcccagcgg gccggggccg
     4621 ccgcccccgg cttccggctc gacgacacca accgcgagac cgtcctgggc atctgccgcc
     4681 gcctcgacgg cgttccgctc gccatcgaac tggcggcggc ccagctgccc gagctgtcgg
     4741 tcgggagcct gtacgagcgc ctcggcgagc ggctgccgtc ccgcctggac ttgctcacca
     4801 ctcgaagcgt ccgcgaccac cgcgactacg gcggcgacca ctgcgaccac catgccgacc
     4861 acggcgactg ccgcctgcgc gacgaccgtg acgaccgtga cgagcgcggg ctgccccgcc
     4921 accaggccct gcgtaccacc atcggctgga gccacgagct gtgcgagccg ctggagcgac
     4981 tgctgtgggc ccggctctcg gtgttcgccg ggaccttcgg ggtggaggcc gccgagcggg
     5041 tctgcgcggg cggcccactg cccgcgcacc gggtggtggg cctgctcgcc cggctgctcg
     5101 acaagtcgat cgtccgccac gaccaacggg accggggccg cctgcggatg ctcgacaccg
     5161 tgcgcgagta cggcaccgac tggctgcgtc ggctcggcga cgtgcaccgt atgcggctgc
     5221 ggcacctgga cttctaccgt gacctggccc gtcgcggctg cgccgagtgg aacaccgccc
     5281 ggcaggtcat gtggtgcgac cggatagtcg ccgagcacag caacctgcgc gcggcggtgg
     5341 acttcgccct ggcggagccg gacacgtcgg tcgccctgga catcacggcg cacgccggtt
     5401 tcctctggcg gcactgcggc tacggccggg acgccgccgc ctgtctggac caggtgctca
     5461 cggtcgacgc ggagccgggg ccggtgcgca ccctggccct ctggagccgg ggctccgtgg
     5521 cgattctcca gggcgacctg gacgtggcgg aggtgtgggc ggatctgacc gcccaggccg
     5581 cggcggagca gggggacgcg cgggtggtcg ccgccgcccg ctatctcgcg ggcagcgcgc
     5641 cgctgttgcg cggccggttg gaggaagcga tcgaggcgta cggttcgtgc ggcttgtacg
     5701 gcccgtccgg tctgtccggc ttatccgact cgtccggccc gttcggctcg tacggctttt
     5761 tcgagtccag cgactggtgt ggttcggcga tgctccaggc acgctgcggg atcaccctcg
     5821 cccacctgtt ggcgggccgg ttcgaccagg ccggggaggt gggtgaggcg ttgtggcggg
     5881 actgcgtccg gatcggggaa cgctgggtgc gggcctggac cgaacccatg ctggcccagg
     5941 tcgcgttggc cgcgggcgac acggccgagg cggaacgccg ggcccgcgag ggggtggtgg
     6001 gccatgagct gctgcacaac accgcgggcg tcggccatgc cctggacgcg ctggccgaag
     6061 ccgtcctggc gcgcggcgac gcggcccgcg ccgccgtgct gctcggcgtc agcgaccggt
     6121 tctggagcct ggcgggcagg ccgcagctgg actcggccga gatgcgcgcg gcccgacgcg
     6181 ccagtgagga ccgcgcccga cgggccatcg gcggcgagga gtacgagaag gagtaccgcg
     6241 caggccagga gatgacctac gaggacggcg tggcctacgc caccgcacgc tggtgagtga
     6301 ccgtgaccgt gaccgcctac gccaccgcgc ggtaggcgac cgggtcgctc cccggtacgg
     6361 cctccgcgtg ccccagcttc accagtcgac gcagatgggc ctcggcctcc gatacggcga
     6421 tgttccgtga tccgtatggg atgtccgccc aggggcggtt ccattccatc cgcacggcga
     6481 gctgccaggg ggtgagcggc gaggcgagca gggcacgtag gccgcgcagc cgctcgtcgt
     6541 ggtggtcgag caactcccgt acccggccag gggcgtcggt gaaggcgtac tggtgggccg
     6601 ggagcacctc ggacacgccc aggcggccga cccgttccag ggaggcgagg tagtcgccga
     6661 gcggatcggt cacggcgctt tcctccgggt cctcgtacaa gccgatatgc ggggtgatcc
     6721 cgggcagcag gtgatcgccg gagaagagcc gccccaggcc cggctttccg gccgggtgct
     6781 cctcttccag gtgcaggcag acatggccgg gggtgtgacc gggggtccag atggcgcgca
     6841 gcctgcggcc cggcaggtcg aggagttcgc cgggggtgat gtcccggtcg gggagcgcgg
     6901 cgtgcagtcc cggcagcgtg cgcatccggc cggactcgcg ggcggccagc aggggagcga
     6961 ggtggtcggc tggggcaccg gcggcggcga gcttgtcggt gaggtagtcg atccagcgtt
     7021 cgggccgctg ctcacgggtg cggcgtacga catgggcgtc ggccgggtgc atcgcgatcc
     7081 aggcacccga ggcctcccgg accttgccgg acaggccgtg atggtcgggg tggtggtgag
     7141 tgatgaccac cccgtgcagc tcaccgatgg cgaccccgca ggcggcgagg cccgccacca
     7201 gggtgtcgta cgactcgggg tcgtcccagc cggtgtcgat caggaccggg ccgcggtcgg
     7261 tgtccaggag gtgtacgagg gtgtggccca gagggttgtc cgggatcggg accttgatgc
     7321 tccatacgcc cccgccgtgc tcggtcaccc gggtcgtcgt ccctgtcgtc gtggggctca
     7381 tggcgacact ataactagaa ctagtttcaa tagtcgccca agtctactga ttcctgggat
     7441 gagttggagg gctttggagg gctggtggca gactcacgcc atgcgtgatc atctggaagc
     7501 cccttcgggg ctggtgctac gtcagtgggc ggccgtggac gcccgcgcgg tactggccgc
     7561 cttcgccgac cctctgatgc gcgagcagag tgccgagccg ctggattcgc tgtccgccgc
     7621 cgagcgctgg atcgccgaac gccaggacga gtggtccgcg gggaccgcct acgccttcgc
     7681 cgtgacggac gggagtgggg gcgggaacgg cggtgccgtg ctggggcaga tgtccatcgg
     7741 cggggtgcat cggcggcacc gcatcggatg ggtgtcgtac tggaccacgg cggcggcccg
     7801 tggccggggc gtcgcttccc gtgcctgccg ggtggccgcc gaatgggcct tcaccgacgc
     7861 cgggctgttc cgcctggagc tgggtcatcg ggtcaacaat cccgcctcgt gcgcggtggc
     7921 ccgagccgcg ggtttcgcgg tggaggggcg ccagcgccag aagctggagt acgacggcgt
     7981 tcgctatgac gtcgaactcc acgcccgcct ggccacggat ccgggcccag ttaatggtgc
     8041 ccacaccgtg gactcctcca actagaactg gtatcagttc tgcaagtctc agccgaaagc
     8101 tgaaacagtg tcaggaaccg cccttcggga ggcagtcagc catgacgacc gagcttgtgg
     8161 aacaccgaaa attgttcatc ggtggggagt tggttgatcc cctgggccag ggcgtcatcg
     8221 aggtgatctc cccgcacacc gagcaggtca tcggacgcgt accgcacgcc gcacccgccg
     8281 acgtggaccg cgccgtcgcc ctcgcgcgcc gggcgttcga cgaaggaccc tggccgcgga
     8341 tgaccctcga cgagcggatc gccgtcgtca cccggatcaa ggacgcgttc gccgtacggc
     8401 acgaggagat cgcccgcgtc atcagctccg agaacggcac cccgtacacc tccagcgtga
     8461 tggtccagtc gctcgcctcg atgatggtgt gggaggcggc cctcgccacc gcccgcgact
     8521 tcacgtacga ggaacggcgc gacggcatcc tcggcaagat cctcgtccgg cgcgaaccgg
     8581 tcggcgtcgt ggcggccgtc gtcccctgga acgtcccgca gttcaccgcc gccgccaagc
     8641 tggcacccgc gctgctcgcg ggctgcccgg tgattctgaa ggtctcgccc gagacgcccc
     8701 tggacgccta cctgctggcc gagatcgcca ccgaggccgg gctccccgaa ggcgtcctct
     8761 cgatcatccc cgccgaccgt gaggtcagcg agtacctggt cgcacacccg ggcgtggaca
     8821 aggtctcctt caccggctcg gtgggcgcgg gcaagcgcgt catggaggtc tgctcccgca
     8881 acctcacccg cgtcaccctg gagttgggcg gcaaatcggc cgcggtcatc ctgccggacg
     8941 ccgacgcggc caccgccgtc gccgggatcg tcccgttcgc ctggatgatc aacggccagg
     9001 cctgcgtggc gcagacccgc atcctcgtcc cacgcggccg ctacgacgag ttcgccgagg
     9061 ccttcgccac cgccgcgggc gcgctgaagg tcggcgaccc gctcgacccg gccaccgaac
     9121 tgggcccgct ggtagccaag cgccagcagc agcgctccct cgactacatc cggatcggcc
     9181 aggaggaggg cgccaagatc ctcaccggcg gcggccgccc ggccggtctt gaccagggct
     9241 ggtacgtcga gccaacgctc ttcggcggcg tcgacaactc catgcggatc gcccgcgagg
     9301 agatcttcgg cccggtcatc tgcctgctcc cgtacggcga cgaggccgag gccgtgaaga
     9361 tcgccaacga ctccgactac ggcctgagcg gcagcgtctg gaccgctgac gtggaacgcg
     9421 gcatcgacgt cgcgcgccgg gtgcggaccg gaacgtacag cgtgaacacc ttcagcctcg
     9481 acatgctcgg gccgttcggc ggctacaaga actccggcct ggggcgggag ttcgggcccg
     9541 agggatacgg cgagtacttc gagcacaaga tgatccacct gcccggcgga tacgaagggt
     9601 gagggcggcc tgatgggaga ccgctggcag gtggaggtcg accggggggt gtgcatcggc
     9661 tccggtatgt gcgtgaacca cgcgccggac ggcttccggc tggacaccgc ccggcagtcg
     9721 caccccgtcg acgcggagac ggacgcgaac gagaaggtgc tcgaggcggc cgaagggtgc
     9781 ccggtggagg cgatcacgat cactctgctg gcgaccgggg aagccgtgtt cccgcccgac
     9841 gagtagcccc gccgctcctc ctgcggacgt gtgtgtccgg aggaggagcg gggcttgatc
     9901 cggcctgtgc gtttcgcacg gtgttccgat gacagtcgtg actgtccgcc ccctcccacg
     9961 ccgtggaaat ctcggtgcga cgcgaccggg aaggggcacg atggacaagc ggtacgaggt
    10021 ctacgcgctg gccgacaggt tcttctacga gacccccaac cgggtgtcca gcaccggcac
    10081 cagcgccacg accaccggta ccactggtgc caccgcgctg tacgagaccg cccgccgccc
    10141 cgtgcccgac gggtggcgaa cccagcgcac cggcgactgg ctcgtcttcg cccccgttga
    10201 cgacaccgga cacccgctga ccgcgccgtc gcagggctgg aagatccatg tctcggcgac
    10261 cggagagaac gccgagaaga ccgccgccgt ggtcgcggac tactgcctgc cgcgcggcat
    10321 ccccttcaag ttcgtgccgg gcgcccggct gctgcacctg cgcaacagca agtacgcgcc
    10381 ccgcgacggc agcggcaagt tcgccaccct ctacccggcc gacggatacc aactccgcac
    10441 cacgctcacc gagttgggtg ggcagctcga cggcttcgac ggcccctacg tgctgaccga
    10501 cctgcgctgg cacaacggac ccctgtacgt ccgatacggc gcgttcgccc ggcggttctg
    10561 cctggacggg cggggcaccc tggtccccgc gatcgagaac gccgccggtg acctcgtacc
    10621 ggacccgcgc gacccggcct tccaggtccc ggagtgggtg aagctccccg gcttcctcga
    10681 accgcacctg gcggcccgca acgcgacgac cgtcagcgac ctcccgtacc gcatcgagaa
    10741 ggccctgcac ttctccaacg gcggcggggt gtacgcgggc accgacaccc gtgacgccag
    10801 ccgggtcgtc ctcaaggaag ggcggccgca cgcgggtctg gccgccgacg gagccgacgc
    10861 cgtcgcccgc ctcgaacgcg agaaggcggc gctggagcgg ctgtccggcc ttggcgtcgc
    10921 acccgaggcg cgcgactggt tcacgctcgg cgaccaccgc ttcctggtca tggacttcct
    10981 gccagggcgc accctcaact ccttcctcgc cgaacgccat ccgctgtgca cctgcgaccc
    11041 ggaccccgcc gccatcgccg actacacgga ctgggcgctg ggcattcacc gcgccgtcga
    11101 ggaggccgtg gcggcggtac acgggcgggg tgtcgtcttc aacgatctcc acctcttcaa
    11161 catcatggtc gcccccgacg agcggtcggt cgcgctgctc gacttcgaag cggccaccac
    11221 cgtcggcgac agcggacgcc aggtcgtcgc ccaccccggg ttcatggccc cggcgggccg
    11281 caccggcacc gacatcgacc gctacgcgct ggcctgcctg cgcatcgccc tgttcctgcc
    11341 gatcacctca ctcttcgcca tcgaccgcgg gaaggccgca cacctggcgg aggtggcggc
    11401 ggggctcttc cccggtatcc cggacggctt ccttgacgag gccgtcacgg agatcacccg
    11461 cgatggcgat cgggcgccgg tcccccaggg gggcgggtcc ggcgccacct cgacgattac
    11521 ggcgggagcg ggcccgggcg ggggagccgg ggcaggggcg gaggcgggcg gatcggcgcg
    11581 gtgggtggcg cttgctgaga ccggggactg gccgcgtagt cgggattcga tggtcgcggc
    11641 gatcctcgcc tccgccacgc cggaccgcga cgaccggctg ttccccggtg acatcgcgca
    11701 gttctccgaa ggcggggggc tcggcctggc gtacggcgcc gcaggagtgc tgcacgccct
    11761 cgccgagacc ggtgccgagc gctacgaaca gggcgagcgc tggctgctcg cgcacaccga
    11821 cccggtgccc gcgggcacgc cgctcggtct gtacgacgga ctcgcgggcg tcgcgtacgt
    11881 actggaccgg ctcggccacc ggcagcgcgc cctcgacctc gccgaccaga tcctgcgcga
    11941 gccatggcag cgcctcaccc cggacctgca cagcggcctc gcgggcctgg gcctcgtgct
    12001 cgacgcactc gcccacacca ccggcgagag cgcactgcgg ggacccgcac tgcgcgccgc
    12061 ggagctcgtc ggcgaccggc tcacggccgc cgagcccggc ccacccgcgt cacgccgcgc
    12121 cgggctgttg cgcggcagca ccggggccgc gctgctcttc ctgcggctgc acgagcgcac
    12181 ccaggacccc gacctgctcg accaggccgc gcgggcgctc cgcgccgacc tgggcgcgtg
    12241 cgtcagtcag ccggacggca gtctcgccgt ggacgagggc tggcgcacca tgccgtacct
    12301 cggcgaaggc agcgtcggca tcggcatggt catcgacgac tacctcgccc ggtctgcccg
    12361 gcccgcccag tcagcccggt cctccgacga ggagttcacc cgggcccgta ccgacatcct
    12421 ggccgccgcc cgctccggct tctacgccca gcccggcctg ttccgagggc gggccgggat
    12481 ggtcctgcac ctcagccgta gtacggcgac cccggagacg gccgccgcgc tggccgctca
    12541 gatcgccggg ctcggctggt acgccatgcc gtacgccggt caactggcct tcccaggcga
    12601 ccagatgatg cggctgtcga tggacctggg caccggcacg gccggttgcc tgctcgcgct
    12661 cggcgccgca ctgggcgaca ccggcgccca ccttccgttc ctgccgccac cgccaccgcc
    12721 accgctgtgg ccctcaagcc gactccgcga cacgtcgtcg acggagtcgt agcaagacga
    12781 gcaatacgtc cccacgtccg aaccaggaaa ggaccatcac catggcactt ctcgacctgc
    12841 agaacatgga gaccgaactc accggcggcg gcgacgtcag ctacgccagc ctgctgctct
    12901 gcggcgacag cggcctcagc gtcctcacct gctgaagctg aaccgttgga ccaggtgacc
    12961 cccggccggg ggtcacctgg tcacacccag ccctctccct gggagatccg gatggcgtcc
    13021 acccggttgc gggcaccggt cttgcgggtg atggccgcca tgtagttgcg cacggtcccg
    13081 ttggacagat ggagccggtc cgcgatctcg gcgaccgacg caccctcggc ggcaagcgac
    13141 agcacactca actcccgtcg ggtcaacggc atctgggacg ccttgaggaa gccgaagccc
    13201 agcgatgcgt cgatgaaacg ttccccccga gcgacctgcc ggatcgcggt gagcagccgc
    13261 tccggtgggc tggccttgtc gacatagcca agcgcgtcaa cctccgcggc ccgccgcagc
    13321 ggcccgggac ggccgggccc gcccaggacg agcaacgagc agccgcccgg ccgcgcggta
    13381 gcggcgcagg ccgccaactt gcccagcgga gggacggcgt acaccgcgtc gcagtccagg
    13441 tccgcgacgc acaagtcggg ccgcagggtg cgcatccggg tgggcgcacc gtcccaggac
    13501 gtatgccaga cctccaagtc ggtttccctg gcgagtcgtt ccgccagggc cgatcgcagc
    13561 agtcgcgagt cgtgcaccag aagtacccgg atcacacctg ctccttcagc tccccgccca
    13621 ccggctgctc cgttcagcgc gcaggtccat tcatagtggc gcggcgtgcc tcatggacgc
    13681 agagaactgg ccaaggggat gcgctggggc gcatggcgtg tcaccgcgtg cgccccctga
    13741 gcttcagtgg acgcccggga ggctggtcgc cgccccggga ggcgggctgg cctccagccc
    13801 tgagcctggg ccacagcgat acggcggcag cgcgacgcgg cccaccaccc gcggcgggat
    13861 gggccaacgg tgctgcggcg gtgcggaagc gggccgtctg agggcccccg aggtggcgca
    13921 gaccgaacgc ctccggggca gcccctcggg gcccgcgcgc cgatcaggct cccgcgccca
    13981 gcccccgacc cgccccgccc ctcggtgttc ccgtcgtccc tgtcgccccc gtcgtccccg
    14041 gcgacgtgag atcgatgagg cggcagaccg tctcgatgtc gatcttcacc tgggcgatcg
    14101 acgcccgccc ggacagccag gtgatcaacg ccgagtgcca ggtgtgctcg atgacccgga
    14161 ccgcggagag ctgctgcggc gtcgggtgct caagccccat cgcgtccagg atgatcgccg
    14221 tggtgagccg ggacacggtg tccacctccg ggctcaccga ccggtcggcg aaggtcagcg
    14281 cccgtaccat cgcgtccgcc agatgcggct cgcgctggag tgcgcggaac gcccgcatca
    14341 gcgtctcggc gacccgctcg gcggcggtgt ccccggccgg agggtgctta cggagcgttc
    14401 cgtgcatgtg ctggagctgg tcctgcatgg tggcgaccag caggtgcacc ttggacggga
    14461 agtaccggta cagcgtgccg agcgcgacgc tggaggactc ggcgacctcg cgcatctgta
    14521 cggcgtcgaa gccgcccttg ctggccagct gggcgctggc gtgcaggatg cggcgccgac
    14581 gggcctcctg gcgctccgtc agaggcgcgg atgcgatgcc ggattccttc gcttccgtag
    14641 tcatatgtcc cgttccacgg tgttccacgg tatgagcggt gcgttcgagc atggtacggg
    14701 ccaggtgcgg gtccggtggt ggcgcgaatc acctgctccg ggcctccccg ccggcttacc
    14761 tgccggtaaa ttcgaagctc cttgaacgat caagtctgaa acttgttcta gattagcgtc
    14821 ccggcgtaac ctcgcgggag ccgcagggag aagggggccg tgagtgaccg ctgaggccat
    14881 ggagaggcat ccgctgcgca tcgcgctcct cacctacaag gggaacccgt tctgcggagg
    14941 ccagggcgtc tacgtacgcc acctctcacg ggaactcacc cgcctcggcc accacgtcga
    15001 ggtgatcggc gcccagccct accccgtact cgacgagggc gtcccactca ccgagctgcc
    15061 cagcctcgac ctgtaccgca gccccgaccc cttccgtacc ccgaagcggt ccgagttccg
    15121 cggctggatc gacgcgctgg agttcgccac catgcgcacc ggcggcttcc ccgagccgct
    15181 gaccttctcg ctgcgcgccc gccgccacct ggccgcccgc cgtggcgagt tcgacgtcgt
    15241 gcacgacaat cagacgctgg gctacggcct gctgggcggc cccgagcgcc tcggtgcccc
    15301 gctggtcacc accatccacc acccgatcac cgtcgaccgc cagctggagc tggacgcggc
    15361 cgccgactgg aagggccgcg cctccgtacg ccgctggtac ggcttcaccc ggatgcagaa
    15421 gcgggtggcc cgccgactgc cctcggtcct caccgtctcc ggcagctccc ggcaggagat
    15481 cgtcgaccac ctcggcgtac gggacgaccg cgtccacgtc gtccacatcg gcgccgacac
    15541 cgacctcttc tcgcccgacc cggcgatacc cgaggtgccg ggccgaatcg tcacgacctc
    15601 cagcgccgac gtcccgctca agggcctgat ccacctgatc gaggccctcg ccaaggtacg
    15661 caccgagaac ccggccgccc atctcgtcgt cgtcggcaag cgcgccgagg acggcccggt
    15721 cgccggggcc atcgagcggt acggcctcca gaacgctgtc gagttcgtca agggcatcac
    15781 cgacgccgaa ctggtcgacc tcgtacgcgg cgcccagatc gcctgcgtgc cctccctgta
    15841 cgagggcttc tcgctgcccg ccgccgaggc catggccacc ggcacgccgc tgctcgccac
    15901 gacgggcggc gccatcccgg aggtcgcggg cccggacggt gagacctgcc tcgcggtgcc
    15961 gccaggcgac gcgggagccc tggccgccgg actgacccgg ctgctgggcg accgggagct
    16021 gcgggcccgc ctcggcgccg cgggccgcga gcgcgtgctc gcccgcttca cctgggccag
    16081 ggccgccgaa ggcaccgccg agcggtaccg cgaggccatc gcgcgtagcg cgggcaccgc
    16141 ccgcgtcgcg ggcagcacga ccggccgctc cgcggccata cgtacggata ctccactggg
    16201 gagcgctcac tgatgctgac cgtcgacttc tcccgcttcc cgctggcggc gggcgaccgc
    16261 gtgctggacc tgggctgcgg cgccgggcgc cacgcgttcg agtgctaccg gcgcggagcg
    16321 cgggtggtgg cgctggacca gaacgcggag gaaatccgcg aggtggccaa gtggttcgcc
    16381 gcgatgaagg aggcgggcga ggcccccgaa ggcgccaccg ccaccgcgat ggagggcgac
    16441 gcgctcgcgc tgcccttccc cgacgcgtcg ttcgatgtcg tgatcatctc cgaggtgatg
    16501 gagcacatcc ccgacgacaa gggcgtactc gccgagatgg tgcgggtcct caggccgggc
    16561 ggccggatcg cggtcaccgt tccccgacac ggcccggaga aggtctgctg ggcgctcagc
    16621 gacgcgtacc acgaggtcga gggagggcac atccgcatct acaaggccga cgaactgctg
    16681 ggcaagatgc gcgaggcggg cctcaagccg tacggcaccc accacgcgca cgcgctgcac
    16741 tcgccgtact ggtggctcaa gtgcgcgttc ggcgtcgaca acgacaaggc gctgccggtc
    16801 cgcgcgtacc acaagctgct ggtctgggac atcatgaaga agccgctcgc caccaagatc
    16861 gccgagcagg cgctgaaccc actgatcggc aagagcttcg tggcgtacgc gacgaagccc
    16921 cacctgccca cggacgtcgt cgctgacctc gccaccgaca ccgcggcggc cgccaagtga
    16981 ccacacccac accccagacg gaacacctgg tcctgcccgg cgtcctgacc gccgaacagg
    17041 ccgcccacac cgtacggggc atcctcgccg gtcagcgcga ggacggcgcc atcccgtggt
    17101 tccggggcca ccatctcgac ccgtgggacc acaccgaggc cgccatggcc ctggacgcgg
    17161 cgggcgaaca cgcggcggcg gcccgcgcgt acgactggct ggcccgccac cagaacccgg
    17221 acggctcctg gtacgcggcc tacgacgacg gcgacgccac gcgccccacc gaccgcagtg
    17281 tggagtccaa cttctccgcg tacatcgccg tcggcgcctg gcaccactac ctgtccaccg
    17341 gcgacgacgc cttcctcgac gccatctggc cacacgtcta cgcggccatc gaatgcgtcc
    17401 tcaccctcca gcagcccggc ggccagatcg gctggaagcg cgaggccgcg gaggagggcg
    17461 gggccgcgga ggagggggtg gccggggacg agagagtggc cggggcgccc gtcaccgacg
    17521 cgctgctcac cggcagctcc tccatccacc aggccctgcg ctgcgccctc gccatcgcgg
    17581 aacagcgcga agagccccag cccgactggg agttggccct tggcgcgctc ggtcatgcga
    17641 tccgcaggca ccccgagcgc ttcctcgaca agaaccgcta ctcgatggac tggtactacc
    17701 cggtactcgg cggcgccatc accgggcccg aggccaaggc ccgcatcgag gagagctggg
    17761 accgcttcgt cgtcccggag ttcggggtgc gctgtgtggt gccgaacccc tgggtgacgg
    17821 gcggcgagag cgccgaactc gccctgacgc tctgggcgat gggggagtcc gaccgagccc
    17881 tgagcatcct ccagtcgatc ggccacctcc gcgacgagga gaccggcctg tactggacgg
    17941 gctacgtcta cgacgaccag gcggtatggc cggtcgagca gaccacctgg acggcgggcg
    18001 cgctgctcct cgcggtagcc gcactcggtg gcgacgaggc gacctgcgcg atcttcgacg
    18061 gcgggcgact gccgcggggc ctgacgccgg actgctgcga ctgacctgtg gagctaggag
    18121 ctaactgaca tgcggagcta ggtgttgagc tccgccagta cgcgcagcgt gtgagcgtcc
    18181 ggtgacatca ccagcaggtc cgtgaccggg cccttgcgcc acaactccag gcgctccgcg
    18241 atgcgttcac gcgggccgac cagggagatc tcgtcggcga aggcgtccgg cacggcgcgt
    18301 acggcctctt ccctgcggcc ttcggcgaag agctgctgga tgcggcgtgc cgcgtcctcg
    18361 aagcccatcc gggccatcag gtcggcgtgg aagttgcggg acgtgtgccc catgccgccg
    18421 atgtagaagc cgagcatcgc cttgaccggg agcagccctt cggcgacgtc gtcgcagacg
    18481 tgcgcgcgga ccatgggcgc gaccatgaag ccgtcgcgca ggcctgtcag cgaggcctcg
    18541 tacacgtccg tccgggtcgg tgaccagtac agcggcagcc agccgtccgc gatgcgggtc
    18601 gtctgcgcga tgttccgcgg cccctcggcg ccgagcagga tgggcagttc agctcgcagg
    18661 gggtgcgtga tcggcttgag cggcttgccg agcccggtgc cgtcggcgcc gtcgtacggc
    18721 agcccatgga actgtccgtc cagcgtgacg ggcccctcgc gtcggagcac ctgccggatg
    18781 acgtcgacgt actcgcgggt cgcggtcagc gggctacgcg gaaacggccg cccgtaccag
    18841 ccctccacca cctgtggccc ggagagcccg aggccgagca gcatgcgccc gccggacagg
    18901 tggtccaggg tgagcgcgtg catcgcggtg gcggtcgggg tgcgggcggc catctgggca
    18961 atcgccgtgc ccagcctgat ccgtgaggtc tgcgccgcga tccaggtcag cggtgtgaac
    19021 acgtcggagc cccaggcctc ggcggtccac accgagtcgt agccgagccg ctcggcctcc
    19081 tgggcgagct ggacgtgctc tgtgccgggg ccacggcccc agtatccgag tgcgagccca
    19141 agccgcatga ctgctgtcct ctctgagagg atctgacgat ccgtcagttt gactggcggt
    19201 tcgcgaactg tacggcgagg acgcggagcg gacaagacag cggcccccgt ccgagtggac
    19261 gggggccgct gcttgaggaa tcaggccgct tcggcgtcag ccgcgctgga tgcccgtggt
    19321 gtcctgcagg acaccacgac ggccgtcctg cgtctgggcc accagacccg ggccgcgctg
    19381 ctcgacggcc aggtaccagg tgcccggcgc cagttcggcg atcggcgtcg gcgaaccgtc
    19441 ctccgcgtac agcgggcggg ccaccggcac ggcgaaccag aacggcgcga agtcagcggc
    19501 gggcgcctgc tgggcctgcg gctgctgcgc ctgctccgaa gcctgctggg cctgcggctg
    19561 acccggctgg ccgccgtacg agggctgcgg ctgacccggc tgcggctgac cgccgtaggg
    19621 ctgctgctgg gcgcccgggt agccgtagcc accctgctgc ggcatgcccg gctggccacc
    19681 gtacggctgc tgacccatca tcggggcggg cgtggcgccc atcagcgggg cgctcagggc
    19741 ggggacgagc ggcgaggaga tggcggcacc agcgagcaga agtgcggaga tcaggccgag
    19801 gatgaggccg gcgcccgcgt cgacgttgtc gctgacgtcg atgatcgtcc agaagaagtt
    19861 ccaggccacg aggatcgtga aggcgatgcc gacctgaccc aggtcaaggc cgatgacctt
    19921 gcgcggctgg ggcaggcagc ggttgacgac gatcaggacc gcgccgatga ccccggccat
    19981 gtacaccccg atgccgttcc cgaggctgtc ccacgagttc gggaggtcga ggtcgcccgt
    20041 ggcgccgctt accgagtaga gatcgaggaa cgaggcgatg aacagcaaca ccgctgctcc
    20101 gatcaccact gcgtcgcctc gagtgagaga gcggaagttc acttcaggtc cttcgtaagt
    20161 cgtcgagtcg gtaggcgtcg ctgtcgccgg tactgcaaac gtatggtgcg aagcgcgggg
    20221 gtggcccccc atcgtacggg cgacagtatc gcccgtacgg tcggggtgtc tgctccgtat
    20281 aaaggtcggc cggcgtgctt cccctgccta ccccttgagg aagccagcga tgccttccga
    20341 gatcccccga gcggccttct gccgccatgt cccattggtg agctgggccg cgtcatcggc
    20401 gtcgcgcatg ttgccacact cgatgaacac cttgggaacc tttgacagat tgagcccgcc
    20461 gaggtccttg cgcacgtcca agccggtgcc gccgccgatg tagttggacg gcgcgttccc
    20521 ggtgcggcgc acgaagccac ccgcgatgcg ctcaccgagc tcgcgggacg gtgcgacgat
    20581 ggcggaggtg tcggcggccc cggccttcac cttgccgggg aggatcacat ggaacccgcg
    20641 gttaccggcg ctggagccgt cggcgtggag ggagacgacg gcgtcggcct tggcctcgtt
    20701 gccgatccgg gcccgctcgt cgatgcaggg gccgtacggc cggtcgttgt cctgcgtgag
    20761 cttcacggtc gcgccctgct cttcgagcag cttgcggagc cggtgcgcga ggtcgaggtt
    20821 gaacgcggcc tcggagtacc cggcgttggt ggcggtgccg gtggtgtcgc actccttgcg
    20881 gtgcgtaccg acgtcgacct ggcgggcgat ttgggtgggg tggtcgcggt tgcggggatt
    20941 gtgcccgggg tcgatgacga cgactttgcc cttgaggggg ccggtgcggg gggtggtgcc
    21001 ggagggcgag ggcgaggggg aggtgctggg cttgggtgag ggtgagggtg tggagctgga
    21061 cgtcgacgcg tcgcctgatg gcttcccgct ggacggcccg tccgtgccgg aaggctcagc
    21121 ggacggactg tccgccgctg aacctgaacc tgaaggggta gctgtcgccg tcgcggtctc
    21181 ccccttcccc gcatcactgc caccgctgtc ctgtgccccg ctcacgccct gccacagcaa
    21241 ccacccgccg agccctacgg gcaccagcgc ggcggccacg acgagcgcgc ggccacgact
    21301 gagggggcgg cggggtgcgg gggacgggct gtcaggatcg tcgtacgaca cgcagcgatg
    21361 ctatcgggcg gtggccgtat gggggtgtac ggcggcgtac cggcgatgta cggcggcgta
    21421 ccggcggtgt agctgtgtac cggcggtgta cggcggctgt ccgcgcgctc agatcccggc
    21481 gccggtgcgc cgcagcacgc gcagcgagtc ggtcaccgag acctccgcga acgcgccgga
    21541 ctccagggcc ctgcggtaga cgcggtacgg agcctggccc ccgtcggccg ggttcgggaa
    21601 gacatcgtgg atgacgagca gcccgccctc cgcgagatgc ggcgcccacc cctcgtagtc
    21661 accggtggcg tgctcgtcgg tgtgcccacc gtcgatgaac acgagcccga gcggcccgcc
    21721 ccacaccttg gcgacctgcg gtgaccgccc gacgacggcg atcacatgct cctcaagccc
    21781 ggcccggtgc agggtccgcc ggaaggtcgg cagtgtgtcc atcagcccga cctccgcgtc
    21841 cacgaccgtc gggtcgtggt actcccaccc cggctgctgc tcctcgctgc cccggtgatg
    21901 atcgacggtg acggccgtcg tccccgcctc ccgcgcggcg tctgcgagca gcaccgtgga
    21961 acgcccgcag tacgtcccga cctccagcaa cggcagccca agccgccccg cctcgacggc
    22021 agcggcgtag agcgcgagcc cctcacccag cggcatgaac cccttggccg cctcaaaggc
    22081 ggcgagcacc tcggccttcg gcgcgggcgc gggcgacggc gcgagtgagg gctcgggtga
    22141 gggctcgggc tcggtcgggg gcgtcgcggc catggccatg ggggtcctcc gggtgggcag
    22201 atgtgatcgg cccatcgtgc cacccaactc tcgggagacg gcctgtcggg gtcggggtgc
    22261 tactggatgt gcggggacag agcacggagg aactcggctg cgtcgaagat cgcgccggcg
    22321 gaggcgacgc caaccgtctc cgctcctgcc ctcgtccgtc ccgtgaggat gcggtcgacc
    22381 gcttccacga cgagcggcgc ggtgatggcg tagatgtcct ggcccctcgc cacggcacgc
    22441 cgttcgctgc cgcccttgcg caccacgaca tcgacgagga aggtctgcgc ggaccgcccg
    22501 ctctcgtcgg ctggcgtcgg tgccggggtg tccggggccg acagatccct ggccgcctcg
    22561 agtgacatgt aggtgcgtac ttcggggatg gacaggtggc tgggaatggt gacgacgtca
    22621 gccatcgtga actccccgat gaccgcccgg gtgcccatgg gggcggggaa cggccactct
    22681 tgggtcggcg aggtgtcgtg gcggagctcc agtcgcccgt tcgtgtacac gacgcgtccg
    22741 ccgccccgcc gctcccggga gaccacgccc gc
//
