LOCUS       NZ_WHOM01000048         6689 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Streptomyces apocyni strain TRM 66233 482, whole genome shotgun
            sequence.
ACCESSION   NZ_WHOM01000048
VERSION     NZ_WHOM01000048.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces apocyni
  ORGANISM  Streptomyces apocyni
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6689)
  AUTHORS   Liu,W.
  TITLE     Streptomyces poacynumensis sp. nov., a endogenous actinomycete
            isolated from Poacynum hendersonii
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6689)
  AUTHORS   Liu,W.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-OCT-2019) Key Laboratory of Protection and Utilization
            of Biological Resources in Tarim Basin of Xinjiang Production &
            Construction Corps, Tarim University, Xingfu Road, Alar, Xinjiang
            843300, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: ABySS v. 2.2.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009739465.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 17:09:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,397
            CDSs (total)                      :: 6,319
            Genes (coding)                    :: 6,205
            CDSs (with protein)               :: 6,205
            Genes (RNA)                       :: 78
            rRNAs                             :: 6, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 34 of 114
            Pseudo Genes (incomplete)         :: 100 of 114
            Pseudo Genes (internal stop)      :: 6 of 114
            Pseudo Genes (multiple problems)  :: 23 of 114
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:56:55
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 6689
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            WHOM01000048.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..6689
                     /collection_date="2018-07"
                     /db_xref="taxon:2654677"
                     /geo_loc_name="China: Xinjiang"
                     /host="Apocynum hendersonii"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces apocyni"
                     /strain="TRM 66233"
                     /type_material="type strain of Streptomyces apocyni"
     gene            complement(<1..>6689)
                     /locus_tag="GCN81_RS12515"
     region          1..6689
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..6689
                     /SMILES="NC(C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..6689
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<0:6689](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(<1..6689)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     CDS             complement(<1..6689)
                     /NRPS_PKS="Domain: Epimerization (1-210). E-value:
                     1.7e-106. Score: 348.7. Matches aSDomain:
                     nrpspksdomains_GCN81_RS12515_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (216-372). E-value: 4.1e-44.
                     Score: 142.1. Matches aSDomain:
                     nrpspksdomains_GCN81_RS12515_TIGR01720.1"
                     /NRPS_PKS="Domain: Cglyc (379-679). E-value: 2.7e-120.
                     Score: 393.0. Matches aSDomain:
                     nrpspksdomains_GCN81_RS12515_Cglyc.1"
                     /NRPS_PKS="Domain: AMP-binding (837-1245). E-value:
                     4.3e-107. Score: 350.1. Matches aSDomain:
                     nrpspksdomains_GCN81_RS12515_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1353-1419). E-value: 8.8e-21.
                     Score: 65.9. Matches aSDomain:
                     nrpspksdomains_GCN81_RS12515_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (1434-1747). E-value:
                     3.5e-141. Score: 463.4. Matches aSDomain:
                     nrpspksdomains_GCN81_RS12515_Epimerization.2"
                     /NRPS_PKS="Domain: TIGR01720 (1752-1907). E-value: 9.8e-43.
                     Score: 137.6. Matches aSDomain:
                     nrpspksdomains_GCN81_RS12515_TIGR01720.2"
                     /NRPS_PKS="Domain: Cglyc (1915-2212). E-value: 7.5e-115.
                     Score: 375.1. Matches aSDomain:
                     nrpspksdomains_GCN81_RS12515_Cglyc.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058215.1"
                     /locus_tag="GCN81_RS12515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_156724638.1"
                     /sec_met_domain="AMP-binding (E-value: 4e-112, bitscore:
                     360.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.3e-15, bitscore:
                     44.0, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 7e-71, bitscore:
                     224.8, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEAEAARSRLAPEAGAMVQAVWFDAGPHAPGKLLLVVHHLVVDGV
                     SWRILLPDLAAAWAGGGQGALEPVGTSFRRWAQQLTTLAQQQNQLDELALWTGMLSAPD
                     PLLTGRPLDPARDTASTARSLTLTLDRDTTQALLTAVPAAFHAGVNDVLLTGLALAVNQ
                     WRRVRGVDASDVLLDLEGHGREDLLPGVDLSRTVGWFTAAHPVRLAPGTTDSPGHALKR
                     VKEQLRAIPDHGIGYGLLRHLNPDTSRTLAALPTPQIGFNYLGRFTAPTNQDWSVDASA
                     GALSGGDDAALALAHAVEVNAYTQDQEEGSQLTAVWSWASGLLSEADAQELGEAWFAAL
                     KSLVAHTAEPGAGGRTPSDLPLVDLDQNHIDLLETTHPHIQDVLPLTPLQEGLLFHAQF
                     DDEAPDVYTVQFTFDLEGPLDIDVLRSAAGALLERHPNLRAGFHRAGLDRPVQIIPAGV
                     TLPWSEVDLSALDDDARTAELARLLDEDRGRRFDVAAPPLLRFTLVRLGAERHQLVLTN
                     HHILLDGWSTALLAKELFERYEAEGAPGPSPAARYADYLAWLARQDQAAAETAWRDALA
                     GLDEPTLLMPAAGEGDEPGTPPAELSVDLSAPLTQALTAAARSRGLTLSTLVQGSWALL
                     LSRLTGRDDVVFGTTVSGRPPELAGVEQMVGLFINTLPVRVRLDPAEPLVDALARFQDE
                     QSRLMAHQHIGLADVQRLAGGGELFDTLAVFENYPIDPRTLQTSASPLRVVGVDGHDAT
                     HYPVTLLAIPGERMQLRLGYRSDVVDGERAATLLRRLTGLLETVTADLDQLTGRITVLS
                     PEERRMLGEWNATSRPLAETDLAAAFEAQADRTPDATAVVYEDTSLSYAELDARANRLA
                     HALIERGAGPERFVALAVPRSAEMIVAALAILKSGAAYLPVDPNYPAERIAYLLADARP
                     ALVITTDAVRETLPADGDGDGDGDGRVLVLDAPGSRPGPESGPAHRPTDRDRMTLLLPQ
                     HPAYVIHTSGSTGQPKGVVIPHRGAVDLAAWAGREIGGPALSRVLAATSLNFDVSVFEV
                     FGPLLCGGSIEVVRDLLSLTEARYEGWSGSLISAVPSAFAQLLGQGNVTARAETVVLAG
                     EALSAQAVADIRAAMPSCRVANIYGPTEAIVYSTAWFADGGAVAGTPPIGRPITNRRAY
                     VLDGGLRPVPPGVPGELYIAGAGLARGYLNRAGLTAERFVADPYGAPGERMYRTGDLVR
                     WESDGNIAYLGRTDHQVKVRGFRIELGEIEAALTAHPGIAHAVALVREDRPGDKRLTAY
                     VVPAAGHPAPQTAELRDHLGQSLPAYMVPAVFVELDALPLTPNGKLDRKALPAPDYATL
                     TTGRTPATAQEELLCGLIADILGLPSVGVDDDFFTLGGDSIISIQLVGRAREAGLVFTP
                     RDVFRHKTAAALAELTQASTDATVEDVHDDGIGQVELTPIMQWLRELNGPIEGFSQSML
                     VRVPAGLGEDRLASALQTVLDHHDALRMRLTRLGGVVWSLEVTERGSVSARDCVQRVDT
                     TGLDGDALRDVLVREAEAARSRLAPEAGAMVQAVWFDAGPDTPGKLLLTIHHLAVDGVS
                     WRILLPDLATAWEAASGTRTAALQPVRTSFRSWAEQLGALAQEREQLDGIALWTDMLSA
                     PDPLLTERPLDPARDTAGTARTLTLTLDSDTTQALLTAVPAAFHAGVNDVLLTGLTLAV
                     NQRRQERGADTGAVLVELEGHGREDVLPGVDLSRTVGWFTAAHPVRLDPGTTDSPGHAL
                     KRVKEQLRAIPDHGIGYGLLRHLNPQTGPLFARLPQPQIGFNYLGRFPAGAEDWAPAAE
                     FAALSGGVDAGLPMPRALDVNAYVADGPDGQRLTATWQWPGELLSQAEVAELGEAWFAA
                     LKSLVAHTAEPGAGGRTPSDLPLLDLDQEQIDAVDAACPGAEVLPLTPLQEGLIFHSQF
                     DDETPDVYTVQLLFDLEGPLDAAALRAAAEGVVRRHAGLRAGFWQEGLDGPVQIIPAEV
                     TLPWTEVDLSALDDDARTAELARLLDEDRGRRFDLAAPPLLRFALIRIGADRHRLVMTN
                     HHILIDGWSLGVLVRDLFQLYARRDGGAGLPRVADHRAYAQWLTEQDRGAAEAVWREVF
                     DGFDEPTLLSPAETAHTSVLPAQIMRELAADVSERLTGAARRAGVTLGTLVQGAWAMVL
                     GALTGRDDVVFGTTVSGRPPEVAGVEQMVGLFINTLPVRVRLNPHTTVGHLLAQLQDQQ
                     SG"
     aSDomain        complement(54..944)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GCN81_RS12515_Cglyc.2"
                     /domain_subtypes="Cglyc"
                     /evalue="7.50E-115"
                     /label="GCN81_RS12515_Cglyc.2"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="2212"
                     /protein_start="1915"
                     /score="375.1"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHILIDG"
                     /tool="antismash"
                     /translation="EVLPLTPLQEGLIFHSQFDDETPDVYTVQLLFDLEGPLDAAALRA
                     AAEGVVRRHAGLRAGFWQEGLDGPVQIIPAEVTLPWTEVDLSALDDDARTAELARLLDE
                     DRGRRFDLAAPPLLRFALIRIGADRHRLVMTNHHILIDGWSLGVLVRDLFQLYARRDGG
                     AGLPRVADHRAYAQWLTEQDRGAAEAVWREVFDGFDEPTLLSPAETAHTSVLPAQIMRE
                     LAADVSERLTGAARRAGVTLGTLVQGAWAMVLGALTGRDDVVFGTTVSGRPPEVAGVEQ
                     MVGLFINTLPVRVRLN"
     CDS_motif       complement(66..161)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GCN81_RS12515_0026"
                     /evalue="1.10E-21"
                     /label="C5_DCL_263-294"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="2208"
                     /protein_start="2176"
                     /score="69.3"
                     /tool="antismash"
                     /translation="DVVFGTTVSGRPPEVAGVEQMVGLFINTLPVR"
     CDS_motif       complement(396..428)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GCN81_RS12515_0025"
                     /evalue="2.30E+00"
                     /label="C4_DCL_171-183"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="2098"
                     /protein_start="2087"
                     /score="2.3"
                     /tool="antismash"
                     /translation="RAYAQWLTEQD"
     CDS_motif       complement(474..539)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GCN81_RS12515_0024"
                     /evalue="4.90E-12"
                     /label="C3_DCL_135-156"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="2072"
                     /protein_start="2050"
                     /score="38.2"
                     /tool="antismash"
                     /translation="NHHILIDGWSLGVLVRDLFQLY"
     CDS_motif       complement(762..875)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GCN81_RS12515_0023"
                     /evalue="8.50E-15"
                     /label="C2_DCL_024-062"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="1976"
                     /protein_start="1938"
                     /score="47.0"
                     /tool="antismash"
                     /translation="DVYTVQLLFDLEGPLDAAALRAAAEGVVRRHAGLRAGF"
     CDS_motif       complement(897..935)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GCN81_RS12515_0022"
                     /evalue="1.80E-03"
                     /label="C1_DCL_004-017"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="1931"
                     /protein_start="1918"
                     /score="10.8"
                     /tool="antismash"
                     /translation="PLTPLQEGLIFHS"
     aSDomain        complement(969..1433)
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GCN81_RS12515_TIGR01720.2"
                     /evalue="9.80E-43"
                     /label="GCN81_RS12515_TIGR01720.2"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="1907"
                     /protein_start="1752"
                     /score="137.6"
                     /tool="antismash"
                     /translation="GHALKRVKEQLRAIPDHGIGYGLLRHLNPQTGPLFARLPQPQIGF
                     NYLGRFPAGAEDWAPAAEFAALSGGVDAGLPMPRALDVNAYVADGPDGQRLTATWQWPG
                     ELLSQAEVAELGEAWFAALKSLVAHTAEPGAGGRTPSDLPLLDLDQEQIDA"
     aSModule        complement(969..5552)
                     /complete
                     /domains="nrpspksdomains_GCN81_RS12515_Cglyc.1"
                     /domains="nrpspksdomains_GCN81_RS12515_AMP-binding.1"
                     /domains="nrpspksdomains_GCN81_RS12515_PCP.1"
                     /domains="nrpspksdomains_GCN81_RS12515_Epimerization.2"
                     /domains="nrpspksdomains_GCN81_RS12515_TIGR01720.2"
                     /locus_tags="GCN81_RS12515"
                     /monomer_pairings="Ala -> D-Ala"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(1284..1313)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GCN81_RS12515_0021"
                     /evalue="2.70E-02"
                     /label="NRPS-E7"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="1802"
                     /protein_start="1792"
                     /score="7.4"
                     /tool="antismash"
                     /translation="PQIGFNYLGR"
     CDS_motif       complement(1353..1415)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GCN81_RS12515_0020"
                     /evalue="1.70E-12"
                     /label="NRPS-E6"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="1779"
                     /protein_start="1758"
                     /score="39.3"
                     /tool="antismash"
                     /translation="VKEQLRAIPDHGIGYGLLRHL"
     aSDomain        complement(1449..2387)
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GCN81_RS12515_Epimerization.2"
                     /evalue="3.50E-141"
                     /label="GCN81_RS12515_Epimerization.2"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="1747"
                     /protein_start="1434"
                     /score="463.4"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLAVDG"
                     /tool="antismash"
                     /translation="GQVELTPIMQWLRELNGPIEGFSQSMLVRVPAGLGEDRLASALQT
                     VLDHHDALRMRLTRLGGVVWSLEVTERGSVSARDCVQRVDTTGLDGDALRDVLVREAEA
                     ARSRLAPEAGAMVQAVWFDAGPDTPGKLLLTIHHLAVDGVSWRILLPDLATAWEAASGT
                     RTAALQPVRTSFRSWAEQLGALAQEREQLDGIALWTDMLSAPDPLLTERPLDPARDTAG
                     TARTLTLTLDSDTTQALLTAVPAAFHAGVNDVLLTGLTLAVNQRRQERGADTGAVLVEL
                     EGHGREDVLPGVDLSRTVGWFTAAHPVRLDPG"
     CDS_motif       complement(1458..1508)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GCN81_RS12515_0019"
                     /evalue="3.60E-08"
                     /label="NRPS-E5"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="1744"
                     /protein_start="1727"
                     /score="25.5"
                     /tool="antismash"
                     /translation="DLSRTVGWFTAAHPVRL"
     CDS_motif       complement(1929..1994)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GCN81_RS12515_0018"
                     /evalue="8.90E-12"
                     /label="NRPS-E2"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="1587"
                     /protein_start="1565"
                     /score="37.1"
                     /tool="antismash"
                     /translation="LLLTIHHLAVDGVSWRILLPDL"
     CDS_motif       complement(2076..2120)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GCN81_RS12515_0017"
                     /evalue="2.20E+01"
                     /label="C3_dual_135-156"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="1538"
                     /protein_start="1523"
                     /score="-1.4"
                     /tool="antismash"
                     /translation="DGDALRDVLVREAEA"
     CDS_motif       complement(2214..2279)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GCN81_RS12515_0016"
                     /evalue="3.30E-05"
                     /label="C2_starter_024-063"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="1492"
                     /protein_start="1470"
                     /score="16.6"
                     /tool="antismash"
                     /translation="DRLASALQTVLDHHDALRMRLT"
     aSDomain        complement(2433..2630)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GCN81_RS12515_PCP.1"
                     /evalue="8.80E-21"
                     /label="GCN81_RS12515_PCP.1"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="1419"
                     /protein_start="1353"
                     /score="65.9"
                     /tool="antismash"
                     /translation="EELLCGLIADILGLPSVGVDDDFFTLGGDSIISIQLVGRAREAGL
                     VFTPRDVFRHKTAAALAELTQ"
     CDS_motif       complement(2925..2990)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GCN81_RS12515_0015"
                     /evalue="3.50E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="1255"
                     /protein_start="1233"
                     /score="38.2"
                     /tool="antismash"
                     /translation="YLGRTDHQVKVRGFRIELGEIE"
     aSDomain        complement(2955..4178)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GCN81_RS12515_AMP-binding.1"
                     /evalue="4.30E-107"
                     /label="GCN81_RS12515_AMP-binding.1"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="1245"
                     /protein_start="837"
                     /score="350.1"
                     /specificity="substrate consensus: Ala"
                     /tool="antismash"
                     /translation="FEAQADRTPDATAVVYEDTSLSYAELDARANRLAHALIERGAGPE
                     RFVALAVPRSAEMIVAALAILKSGAAYLPVDPNYPAERIAYLLADARPALVITTDAVRE
                     TLPADGDGDGDGDGRVLVLDAPGSRPGPESGPAHRPTDRDRMTLLLPQHPAYVIHTSGS
                     TGQPKGVVIPHRGAVDLAAWAGREIGGPALSRVLAATSLNFDVSVFEVFGPLLCGGSIE
                     VVRDLLSLTEARYEGWSGSLISAVPSAFAQLLGQGNVTARAETVVLAGEALSAQAVADI
                     RAAMPSCRVANIYGPTEAIVYSTAWFADGGAVAGTPPIGRPITNRRAYVLDGGLRPVPP
                     GVPGELYIAGAGLARGYLNRAGLTAERFVADPYGAPGERMYRTGDLVRWESDGNIAYLG
                     RTDHQVKVR"
     CDS_motif       complement(3075..3164)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GCN81_RS12515_0014"
                     /evalue="1.20E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="1205"
                     /protein_start="1175"
                     /score="55.9"
                     /tool="antismash"
                     /translation="PPGVPGELYIAGAGLARGYLNRAGLTAERF"
     CDS_motif       complement(3630..3668)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GCN81_RS12515_0013"
                     /evalue="3.20E+01"
                     /label="NRPS-E2"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="1020"
                     /protein_start="1007"
                     /score="-2.2"
                     /tool="antismash"
                     /translation="VIPHRGAVDLAAW"
     CDS_motif       complement(3657..3716)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GCN81_RS12515_0012"
                     /evalue="2.40E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="1011"
                     /protein_start="991"
                     /score="29.2"
                     /tool="antismash"
                     /translation="AYVIHTSGSTGQPKGVVIPH"
     CDS_motif       complement(3951..3992)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GCN81_RS12515_0011"
                     /evalue="8.80E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="913"
                     /protein_start="899"
                     /score="15.8"
                     /tool="antismash"
                     /translation="LAILKSGAAYLPVD"
     CDS_motif       complement(4503..4616)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GCN81_RS12515_0010"
                     /evalue="1.10E-18"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="729"
                     /protein_start="691"
                     /score="59.6"
                     /tool="antismash"
                     /translation="QDEQSRLMAHQHIGLADVQRLAGGGELFDTLAVFENYP"
     aSDomain        complement(4653..5552)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GCN81_RS12515_Cglyc.1"
                     /domain_subtypes="Cglyc"
                     /evalue="2.70E-120"
                     /label="GCN81_RS12515_Cglyc.1"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="679"
                     /protein_start="379"
                     /score="393.0"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHILLDG"
                     /tool="antismash"
                     /translation="IQDVLPLTPLQEGLLFHAQFDDEAPDVYTVQFTFDLEGPLDIDVL
                     RSAAGALLERHPNLRAGFHRAGLDRPVQIIPAGVTLPWSEVDLSALDDDARTAELARLL
                     DEDRGRRFDVAAPPLLRFTLVRLGAERHQLVLTNHHILLDGWSTALLAKELFERYEAEG
                     APGPSPAARYADYLAWLARQDQAAAETAWRDALAGLDEPTLLMPAAGEGDEPGTPPAEL
                     SVDLSAPLTQALTAAARSRGLTLSTLVQGSWALLLSRLTGRDDVVFGTTVSGRPPELAG
                     VEQMVGLFINTLPVRVRLD"
     CDS_motif       complement(4665..4760)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GCN81_RS12515_0009"
                     /evalue="2.20E-22"
                     /label="C5_DCL_263-294"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="675"
                     /protein_start="643"
                     /score="71.5"
                     /tool="antismash"
                     /translation="DVVFGTTVSGRPPELAGVEQMVGLFINTLPVR"
     CDS_motif       complement(5001..5036)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GCN81_RS12515_0008"
                     /evalue="3.80E-02"
                     /label="C4_DCL_171-183"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="563"
                     /protein_start="551"
                     /score="7.3"
                     /tool="antismash"
                     /translation="YADYLAWLARQD"
     CDS_motif       complement(5076..5141)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GCN81_RS12515_0007"
                     /evalue="7.10E-10"
                     /label="C3_DCL_135-156"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="538"
                     /protein_start="516"
                     /score="31.3"
                     /tool="antismash"
                     /translation="NHHILLDGWSTALLAKELFERY"
     CDS_motif       complement(5361..5477)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GCN81_RS12515_0006"
                     /evalue="1.20E-16"
                     /label="C2_DCL_024-062"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="443"
                     /protein_start="404"
                     /score="52.9"
                     /tool="antismash"
                     /translation="DVYTVQFTFDLEGPLDIDVLRSAAGALLERHPNLRAGFH"
     CDS_motif       complement(5502..5537)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GCN81_RS12515_0005"
                     /evalue="7.40E-04"
                     /label="C1_dual_004-017"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="396"
                     /protein_start="384"
                     /score="12.5"
                     /tool="antismash"
                     /translation="PLTPLQEGLLFH"
     aSDomain        complement(5574..6041)
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GCN81_RS12515_TIGR01720.1"
                     /evalue="4.10E-44"
                     /label="GCN81_RS12515_TIGR01720.1"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="372"
                     /protein_start="216"
                     /score="142.1"
                     /tool="antismash"
                     /translation="GHALKRVKEQLRAIPDHGIGYGLLRHLNPDTSRTLAALPTPQIGF
                     NYLGRFTAPTNQDWSVDASAGALSGGDDAALALAHAVEVNAYTQDQEEGSQLTAVWSWA
                     SGLLSEADAQELGEAWFAALKSLVAHTAEPGAGGRTPSDLPLVDLDQNHIDL"
     aSModule        complement(5574..6686)
                     /domains="nrpspksdomains_GCN81_RS12515_Epimerization.1"
                     /domains="nrpspksdomains_GCN81_RS12515_TIGR01720.1"
                     /incomplete
                     /locus_tags="GCN81_RS12515"
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       complement(5892..5921)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GCN81_RS12515_0004"
                     /evalue="2.70E-02"
                     /label="NRPS-E7"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="266"
                     /protein_start="256"
                     /score="7.4"
                     /tool="antismash"
                     /translation="PQIGFNYLGR"
     CDS_motif       complement(5961..6023)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GCN81_RS12515_0003"
                     /evalue="1.70E-12"
                     /label="NRPS-E6"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="243"
                     /protein_start="222"
                     /score="39.3"
                     /tool="antismash"
                     /translation="VKEQLRAIPDHGIGYGLLRHL"
     aSDomain        complement(6060..6686)
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GCN81_RS12515_Epimerization.1"
                     /evalue="1.70E-106"
                     /label="GCN81_RS12515_Epimerization.1"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="210"
                     /protein_start="1"
                     /score="348.7"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVVDG"
                     /tool="antismash"
                     /translation="EAEAARSRLAPEAGAMVQAVWFDAGPHAPGKLLLVVHHLVVDGVS
                     WRILLPDLAAAWAGGGQGALEPVGTSFRRWAQQLTTLAQQQNQLDELALWTGMLSAPDP
                     LLTGRPLDPARDTASTARSLTLTLDRDTTQALLTAVPAAFHAGVNDVLLTGLALAVNQW
                     RRVRGVDASDVLLDLEGHGREDLLPGVDLSRTVGWFTAAHPVRLAP"
     CDS_motif       complement(6066..6116)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GCN81_RS12515_0002"
                     /evalue="3.60E-08"
                     /label="NRPS-E5"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="208"
                     /protein_start="191"
                     /score="25.5"
                     /tool="antismash"
                     /translation="DLSRTVGWFTAAHPVRL"
     CDS_motif       complement(6528..6593)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GCN81_RS12515_0001"
                     /evalue="1.60E-11"
                     /label="NRPS-E2"
                     /locus_tag="GCN81_RS12515"
                     /protein_end="54"
                     /protein_start="32"
                     /score="36.3"
                     /tool="antismash"
                     /translation="LLLVVHHLVVDGVSWRILLPDL"
ORIGIN
        1 ccggactgct ggtcctgcaa ctgggccagc aggtggccga cagtggtgtg cgggttcagg
       61 cgtacgcgaa cggggagggt gttgatgaag aggccgacca tctgctccac gcccgccacc
      121 tccggcggac ggccggagac ggtcgtaccg aagaccacgt cgtcacgacc ggtcagcgcg
      181 ccgagcacca tcgcccaggc accctgcacc aacgtcccca acgtcacacc cgcccgccgg
      241 gcagcacccg tcagacgctc cgacacatcc gcagccagct cccgcatgat ctgggcagga
      301 agcacggaag tgtgcgccgt ctcggcgggt gacagcagcg tcggctcgtc gaaaccgtcg
      361 aacacctccc gccacacggc ttccgccgcg ccccggtcct gctcagtgag ccactgcgca
      421 taggcacggt gatcagccac acgcggcaga cccgccccgc cgtcacgccg cgcgtacagc
      481 tggaacaggt cccgaaccag cacgcccagc gaccagccgt cgatcaggat gtggtggttg
      541 gtcatgacca gacggtgccg gtcggcgccg atccggatga gggcgaagcg cagcagtggg
      601 ggcgccgcca gatcgaagcg gcggccccgg tcctcgtcca gcagccgtgc cagctccgcc
      661 gtccgcgcgt cgtcgtccag cgcggacagg tccacctcag tccagggcag ggtcacctcg
      721 gccgggatga tctggaccgg cccgtccaga ccctcctgcc agaaacccgc ccgcagaccg
      781 gcgtgccggc gcacgacacc ctccgcagcg gcccgcagcg cggccgcgtc cagcggtccc
      841 tccagatcga acagcaactg gacggtgtag acgtcgggtg tctcgtcgtc gaactgggag
      901 tggaagatca gcccttcctg caacggtgtg agcggcagta cctccgcccc cgggcaggcg
      961 gcgtcgacgg cgtcgatctg ctcctgatcg aggtcgagca gtggcaggtc ggagggggtg
     1021 cggccgcccg cgccgggttc ggcggtgtgt gcgacgagcg acttcagcgc cgcgaaccac
     1081 gcctcgccca gctccgcgac ctcggcctgc gacagcagtt cgcccggcca ctgccaggtg
     1141 gccgtcagcc gctggccgtc cggcccgtcc gcgacgtacg cgttgacgtc cagggcgcgc
     1201 ggcatcggca ggccggcgtc cacgccgccg ctgagcgcgg cgaactccgc cgccggagcc
     1261 cagtcttcgg cgcccgcggg gaacctgccg aggtagttga aaccgatctg cggctggggc
     1321 agtcgggcga acagcgggcc cgtctgcggg ttgaggtggc gcagcagtcc gtagccgatg
     1381 ccgtggtcgg gaatggcgcg cagctgctcc ttcacccgct tcaacgcgtg tccggggctg
     1441 tcggtggtgc cggggtcgag gcggaccggg tgggcggcgg tgaaccagcc cacggtccgg
     1501 gacaggtcca ccccgggcag tacgtcctca cgaccgtgcc cttccagctc gacgagtacc
     1561 gcgccggtgt cggcgccccg ctcctggcgc cgctggttga cggcgagggt gaggccggtg
     1621 agcaggacgt cgttgacacc cgcgtggaac gcggcgggga cagcggtgag cagggcctga
     1681 gtcgtgtcgc tgtcgagggt cagggtgagg gtgcgggccg taccggcggt gtcgcgtgcc
     1741 gggtcgaggg gacgctcggt cagcagcggg tcgggcgcgg acagcatgtc ggtccacagc
     1801 gcgatcccgt ccagctgttc acgttcctgc gcgagggcgc cgagctgttc ggcccagctg
     1861 cggaacgagg tgcggaccgg ctgtagggcc gcggtgcggg tgccggacgc ggcttcccag
     1921 gcggtggcga ggtcggggag caggatgcgc caggacacgc cgtccacagc gaggtggtgg
     1981 atggtcagca gcagcttgcc cggggtgtcc ggtcccgcgt cgaaccacac ggcctgcacc
     2041 atcgccccgg cctccggggc gagcctgctc cgggcggcct cggcctcccg caccagcaca
     2101 tcccgcagcg cgtcgccgtc caggccggtg gtgtccaccc gctggacgca gtcgcgcgca
     2161 gagacactgc cgcgctcggt gacctcaagt gaccacacca caccgcccag ccgcgtcagc
     2221 cgcatgcgca gcgcgtcatg gtggtccagt acggtctgga gcgccgacgc gagccggtcc
     2281 tcgcccagcc ccgcgggcac ccgcaccagc atcgactggc tgaacccttc gatgggcccg
     2341 ttcagttcgc gcagccactg catgatcggc gtcagctcga cctggccgat gccgtcgtcg
     2401 tggacgtcct cgacggtggc gtccgtggac gcctgggtca gctcggccag ggccgcggcc
     2461 gtcttgtgcc ggaagacgtc gcgtggggtg aacaccagac cggcttcacg ggcgcggccg
     2521 accagttgga tggagatgat gctgtcgccg ccgagcgtga agaagtcgtc gtccacgccc
     2581 acggacggca gcccgaggat gtcggcgatc agcccgcaca ggagttcctc ctgcgcggtg
     2641 gccggggtgc gcccggtcgt gagggtggcg tagtcgggcg cgggcagtgc cttgcggtcc
     2701 agcttgccgt tcggggtcag cggcagcgcg tcgagctcta cgaagacggc cgggaccatg
     2761 tacgcgggca ggctctggcc caggtggtcg cgcagttccg cggtctgcgg cgcggggtgt
     2821 ccggccgcgg ggacgacgta cgcggtcagg cgcttgtcgc ccggccggtc ctcgcgcacc
     2881 agcgcgacgg cgtgggcgat gcccggatgc gcggtcagcg cggcctcgat ctcgcccagt
     2941 tcgatccgga atccgcggac cttgacctgg tggtcggtgc ggcccaggta cgcgatgttc
     3001 ccgtccgact cccagcggac caggtcgccg gtacggtaca tccgctcgcc cggcgccccg
     3061 taggggtcgg cgacgaagcg ttcggcggtc aggcccgcac ggttcagata gccgcgcgcc
     3121 agcccggccc cggcgatgta cagctcgccg ggtacgcccg gcggcaccgg acgcagcccg
     3181 ccgtccagca cgtaggcccg ccggttggtg atcggccggc cgatcggcgg cgtacccgcc
     3241 acggcaccgc cgtcggcgaa ccaggccgtg gagtagacga tggcctccgt cggaccgtag
     3301 atgttcgcca cccggcacga cggcatggcg gcacggatgt cggcgaccgc ctgcgccgac
     3361 agcgcctcgc ccgccagcac caccgtctcc gcgcgtgccg tcacgttccc ttggccgagc
     3421 aactgcgcga aggccgaggg caccgcgctg atcaggctgc ccgaccaccc ctcgtaccgg
     3481 gcctcggtga gcgacagcag gtcgcgtacg acctcgatgc tcccgccgca cagcagcggg
     3541 ccgaacacct cgaagacgga cacgtcgaag ttgagcgagg tggcggcgag cacccgcgac
     3601 agggccggcc caccgatctc gcggcccgcc cacgcggcga ggtccaccgc tccccggtgg
     3661 gggatgacca cgcccttcgg ctgccccgtc gaacccgagg tgtggatcac gtacgccggg
     3721 tgctgcggca gcagcagagt catgcggtca cggtccgtcg gccggtgggc agggccactc
     3781 tccggcccag gccgtgagcc gggcgcgtca agcaccagca ccctgccgtc gccgtcgccg
     3841 tcgccgtcgc cgtccgcggg cagggtctcg cgcaccgcgt cggtggtgat gaccagggcg
     3901 ggccgcgcgt cggcgaggag gtaggcgatg cgctccgccg ggtagttcgg gtccaccggc
     3961 agataggcgg caccggactt caggatcgcc agtgcggcga cgatcatctc cgccgagcgc
     4021 ggcaccgcca gcgcgacgaa ccgctcgggc ccggcccccc gctcgatcag cgcatgggcc
     4081 aaccggttgg ctcgcgcgtc cagttcggcg tacgaaagcg aggtgtcctc gtacaccacc
     4141 gcggtcgcgt ccggcgtacg gtccgcctgc gcctcgaacg ccgcggccag atcggtttcg
     4201 gccagtggcc tggaggtggc gttccactcc ccgagcatcc ggcgctcctc gggcgacagc
     4261 acggtgatcc gcccggtgag ctggtcgagg tccgcggtca ccgtctccag cagcccggtc
     4321 aggcggcgca gcagcgtcgc ggcccgctct ccgtcgacga catcgctgcg gtagccgagc
     4381 cgcagctgca tgcgctcacc gggaatggcg agcagcgtca ccgggtagtg cgtcgcgtcg
     4441 tgcccgtcca cgccgaccac gcgcagcggc gaggcggagg tctggagagt acgcgggtcg
     4501 atcgggtagt tctcgaagac ggcgagggtg tcgaacagtt cgccgccccc ggccagccgc
     4561 tgtacgtcgg ccagcccgat gtgctggtgc gccatcagcc gtgactgctc gtcctggaac
     4621 cgggccaggg cgtcgaccag cggctccgcg gggtccaggc gtacgcgcac cggcagcgtg
     4681 ttgatgaaga ggccgaccat ctgctccacg cccgccagct ccggcggacg gcccgagacg
     4741 gtcgtgccga agaccacgtc gtcgcggccg gtcagacggc tgagcagcaa ggcccaggag
     4801 ccctgcacca gcgtgctcag cgtcagaccg cgggaccggg cggcagcggt cagcgcctgc
     4861 gtgagcgggg ccgacaggtc aacggacagc tcggcgggcg gcgtgcccgg ctcgtcccct
     4921 tcgcctgccg ccggcatcag cagcgtgggc tcgtccagcc ctgccagggc atcccgccag
     4981 gcggtctccg ccgccgcctg gtcctgccgg gccagccagg cgaggtagtc ggcgtaccgg
     5041 gcggcggggg acgggcccgg ggcgccctcg gcctcgtacc tctcgaagag ctccttggcc
     5101 agcagcgccg tggaccaacc gtccaacagg atgtggtggt tcgtcaggac gagctggtgg
     5161 cgctccgcgc ccaggcgcac cagcgtgaac cggagcagcg gcggcgcggc cacgtcgaag
     5221 cggcggcccc ggtcctcgtc cagcagccgt gccagctccg ccgtgcgcgc gtcgtcgtcc
     5281 agcgcggaca ggtccacctc actccagggc agggtcaccc cggccgggat gatctggacc
     5341 ggccggtcaa gaccggcgcg gtggaatccc gcgcgcaggt tcgggtgccg ctccagcagc
     5401 gccccggcgg ccgaccgcag gacgtcgatg tcgagcggcc cttccaggtc gaaggtgaac
     5461 tggacggtgt agacgtcggg tgcctcgtcg tcgaactggg cgtggaacag cagtccttct
     5521 tggaggggtg tgagggggag gacgtcttgg atgtgggggt gggtggtttc caggaggtcg
     5581 atgtggttct gatcgaggtc gaccaggggc aggtcggagg gggtgcggcc gcccgcgccc
     5641 ggttcggcgg tgtgtgcgac gagcgacttc agcgccgcga accacgcctc gcccaactcc
     5701 tgggcgtcgg cctccgagag cagacccgac gcccatgacc acacggccgt gagctgggaa
     5761 ccctcctcct ggtcctgggt gtacgcgttc acctcgacgg cgtgcgcgag cgccagggcg
     5821 gcgtcgtcac caccggacag ggcgcctgcc gaggcgtcca ctgaccagtc ttggttggtg
     5881 ggtgcggtga atcggccgag gtagttgaag ccgatctgcg gggtggggag tgcggcgagg
     5941 gtacggctgg tgtcggggtt gaggtggcgc agcagcccgt agccgatgcc gtggtcggga
     6001 atcgcgcgca gctgctcctt cactcgcttc aacgcgtgtc cggggctgtc agtggtgccg
     6061 ggggcgaggc ggaccgggtg ggcggcggtg aaccagccca cggtccggga cagatccacc
     6121 ccgggcagca gatcctcacg gccgtgccct tcgagatcga gcaggacgtc ggacgcgtct
     6181 acgcccctca cacgccgcca ctggttgacg gcgagggcga ggccggtgag caggacgtcg
     6241 ttgacacccg cgtggaacgc ggcggggaca gcggtgagca acgcctgagt cgtgtcacgg
     6301 tccagcgtca gggtgagact gcgggcggtg ctggcggtgt cgcgtgccgg gtcgagggga
     6361 cgcccggtca gcagcgggtc gggcgcggac agcatcccgg tccacagcgc gagttcgtcg
     6421 agctggttct gctgctgggc gagggtggtc agttgctggg cccagcggcg gaaggaggta
     6481 cccaccggct ccaaggcgcc ttggccccct cctgcccagg cggcggccag gtcagggagc
     6541 aggatgcgcc aggacacacc gtccaccacc aggtggtgga cgacaaggag gagcttgccg
     6601 ggggcatggg gtcccgcgtc gaaccacacg gcctgcacca tcgccccggc ctccggggcg
     6661 agcctgctcc gggcggcctc ggcctcccg
//
