LOCUS       NZ_WHOM01000036        22639 bp    DNA     linear   CON 10-DEC-2024
DEFINITION  Streptomyces apocyni strain TRM 66233 452, whole genome shotgun
            sequence.
ACCESSION   NZ_WHOM01000036
VERSION     NZ_WHOM01000036.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces apocyni
  ORGANISM  Streptomyces apocyni
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 493755)
  AUTHORS   Liu,W.
  TITLE     Streptomyces poacynumensis sp. nov., a endogenous actinomycete
            isolated from Poacynum hendersonii
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 493755)
  AUTHORS   Liu,W.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-OCT-2019) Key Laboratory of Protection and Utilization
            of Biological Resources in Tarim Basin of Xinjiang Production &
            Construction Corps, Tarim University, Xingfu Road, Alar, Xinjiang
            843300, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: ABySS v. 2.2.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009739465.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 17:09:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,397
            CDSs (total)                      :: 6,319
            Genes (coding)                    :: 6,205
            CDSs (with protein)               :: 6,205
            Genes (RNA)                       :: 78
            rRNAs                             :: 6, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 34 of 114
            Pseudo Genes (incomplete)         :: 100 of 114
            Pseudo Genes (internal stop)      :: 6 of 114
            Pseudo Genes (multiple problems)  :: 23 of 114
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:56:55
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 444235
            Orig. end                         :: 466874
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            WHOM01000036.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22639
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="4"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22639
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22639
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12639](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12639)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(189..204)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.97"
                     /tool="antismash"
     gene            complement(830..1387)
                     /locus_tag="GCN81_RS05605"
     CDS             complement(830..1387)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020550768.1"
                     /locus_tag="GCN81_RS05605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_156722309.1"
                     /transl_table=11
                     /translation="MFAVSLGNGAELRPLEPWQAEEFLAHMDRGRDFIGQYVGLPDVTS
                     NLDATRRWLQVYADKAAADAGRLYGIWLDGLLVGGVLFRVFDACRGTCEAGCWVEPDAA
                     GQGLVTRAVRVLIDWAVEERGMHRVEWQVSSKNTPSINLAKRLGMTREGVLRENDPYRG
                     IRQDTEIWSVLAPEWKAARGAS"
     gene            1586..2800
                     /locus_tag="GCN81_RS05610"
     CDS             1586..2800
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009995088.1"
                     /locus_tag="GCN81_RS05610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="S8 family peptidase"
                     /protein_id="WP_156722310.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 1.3e-29, bitscore:
                     98.1, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRIRVGVRRRVVVAVALAAALGLGLGAVPAAGAEGLASADAEGY
                     ADAEGYIVTFDGSGVRLSSASQDARSLVARSGAVINRTYRTALNGFAVTATRQQAARLA
                     ADPAVRSVVRDTPVAALGVQTDPPWNLDRIDQERLPLDGLYRYPDSAGRGVTAYVLDTG
                     VRITHREFGGRAAYGVDTVDGDDTAQDGNGHGTHVAGIIAGRKYGVAKKARVVAVRVLN
                     DSGGGTASGVIAGIDWVTRHASGPSVANMSLGGPANEALDEAVRNSVAAGITYAVAAGN
                     SNTDAGRFSPARVAEALTVSSTDAGDVRASSANYGTAIDLFAPGRNITSAWNTSDCALA
                     TLSGTSMAAAQVTGAAALQLGESPYDSPARVAKSLTEGASGGVVSGPGAGSPNRLLNVG
                     GIGTR"
     gene            2942..3703
                     /locus_tag="GCN81_RS05615"
     CDS             2942..3703
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019764024.1"
                     /locus_tag="GCN81_RS05615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HNH endonuclease family protein"
                     /protein_id="WP_156722311.1"
                     /transl_table=11
                     /translation="MRRRRRGWWLGCVAVGALIATSGCGLVESNPEPDGSAPPTAEASG
                     GTDDTGGGTGGTDSPGDGKPAAEGTLPNVPTVEAARTQLAGLKVAPHGSMSGYSRSSFS
                     HWAQQGDKCDSREVVLERDGKDVQRDDECKAVSGTWVSAFDGVTLDSASKVDIDHIVPL
                     ANAWRSGAARWDADKRKAFANDLEQPQLIAASASSNRSKGDQGPDEWQPPEKSYWCTYG
                     RAWTAVKSSYELSVTESEKGMLKDMLDTCES"
     gene            3700..4023
                     /locus_tag="GCN81_RS05620"
     CDS             3700..4023
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005477370.1"
                     /locus_tag="GCN81_RS05620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_407697936.1"
                     /transl_table=11
                     /translation="MSDSTSASPGPVPSADDIAAIAPLVGQVVAGPGGAMTDEVGVITG
                     DITVATAPLPDGRAVVAVQYTDADEWYLLSGGPVPVPAGGLDELHHEVLELIKKGGGAE
                     VPR"
     gene            complement(4037..5182)
                     /locus_tag="GCN81_RS05625"
     CDS             complement(4037..5182)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018841094.1"
                     /locus_tag="GCN81_RS05625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_156722312.1"
                     /transl_table=11
                     /translation="MRRRHFISGLTGTAAGVGLAAASTTTAAAATAAALQRPTNAAETW
                     REVPAPPGEEAARLVGVAAAGPAIAFAVGDEGRSRSTRGRPLALAWNGTAWSRTDLTHL
                     DYTGALRAVANSSADAAWALGTNTDGNDQLLAWDGETWQEVNFPGRGEPGTRLTDVAVG
                     GDGQAWVSGRHGDRAGLMRGPGPGNGPAWRWCRPLPDEATPTPYGVHVTPCGEVWVYGD
                     VIARWDGAWTVIPRHVGIRSGVTGLLPVAHDDIWLTGYAYGPGGPPGKPPGVTFQRWDG
                     GEWTRGESPFTVGVLSGIIGDAQGRPDLIAGWDFWDQKRTHYLRWNGSDWTSERGPEAT
                     GSTSLMNAITAIPGTASGYWAVGANSTYSSPPAQLRVERHG"
     misc_feature    complement(4922..4924)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            5377..6039
                     /locus_tag="GCN81_RS05630"
     CDS             5377..6039
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020133446.1"
                     /locus_tag="GCN81_RS05630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_156722390.1"
                     /transl_table=11
                     /translation="MAGRATAAQRRIISAAEAVTGRIVGSEAQLEGLVRRGLAFRHPRP
                     PRAYFLTPAGHRLRDELLAATPPPPAPVTDAATGVFTARTGGEGDPVAGPGRQREVHSA
                     WQGLLELRRMTRPDGDTGRPCGWERTHLVQAAALALEAAGCMPAGAEDTGGGYRVAESP
                     QPEAVAVRLIPGGGGMDDDGLGGLGGCAAALEAAGWQVSEHQERGGGRCLLASPRRD"
     gene            complement(6064..6384)
                     /locus_tag="GCN81_RS05635"
     CDS             complement(6064..6384)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521563.1"
                     /locus_tag="GCN81_RS05635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_156722313.1"
                     /transl_table=11
                     /translation="MIPTEKLSDPAVRALVTALNANDRTAFLAALTPDATMSDDGSDRN
                     LAEWTEKEIFSAGGHMDVESESDGGRTLVAQYRNDTWGEMRTRWHFTVSDGKVSRFETG
                     QA"
     misc_feature    6523..6532
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 16.31"
                     /tool="antismash"
     gene            6563..7870
                     /locus_tag="GCN81_RS05640"
     CDS             6563..7870
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019071193.1"
                     /locus_tag="GCN81_RS05640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VWA domain-containing protein"
                     /protein_id="WP_156722314.1"
                     /transl_table=11
                     /translation="MITRKRLAAGACTLLAALTAGLLPAATGTAFADDPRGGDGPAPKV
                     ELVLDVSGSMRARDMDGGSRMAAAKQAFNEVLDATPDEVELGIRTLGANYRGDDRKEGC
                     KDTAQLYPVGVLSKSARTEAKTAVATLAPTGWTPIGPALLKAADDLEGGDEATSRRIVL
                     ITDGEDTCAPLDPCEVARDIAAKGINLTIDTLGLVPDAKTRDQLSCIADATGGTYSSIR
                     HKDELSDRVNQLVDRAAEPVITPVAVEGADQCAKAPKIGSGLYTDREKFGEHRWYQVDV
                     KPGQELRASVSVAADRQVDNDYGVLLRATTVHGREIVRGESAGSGRTDVISAGLRYPKA
                     DSEDTDDADGAGEPETVCLRVSNSFSAPASVKREPGLPVELTIDLVDGPSDASDVAFFG
                     LGRGWWLLGALAVAGFLGGVLWGWLARWRGAVTRSN"
     gene            7870..8751
                     /locus_tag="GCN81_RS05645"
     CDS             7870..8751
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983446.1"
                     /locus_tag="GCN81_RS05645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_156722315.1"
                     /transl_table=11
                     /translation="MGITKALRVGVSAALLAGTALFGAAGTAWADDPSSSPSADGDSGD
                     GGSDSNGGDGPTEAGTSFRTAVGFEPGQRATAAASTGEYLYWKFLADTGQRPTVKATVK
                     LPEPSARKGTQTWQVDVYDGLRRRQACMYGAQTRKAAQNAESVSLSCTLRPVRAWSEQW
                     SDDPLPGTYYVRLTVTGLKATDLGLPVQAEVETTFKDVGGSHAVDGSLAAPLVAGNGDA
                     ADADSGPGSGSDSGSGNSSARQAAAAAEPEDGWASGWWSDRWLWTAAGGFVAALTGVGG
                     YCLARGPGRPRA"
     misc_feature    complement(9435..9450)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.24"
                     /tool="antismash"
     gene            9526..9651
                     /locus_tag="GCN81_RS32680"
     CDS             9526..9651
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GCN81_RS32680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_267904558.1"
                     /transl_table=11
                     /translation="MNVKAQMTIKGSTSLTWISVQVIVIVIVVLSANSYLACLVR"
     gene            complement(10001..10738)
                     /locus_tag="GCN81_RS05650"
     CDS             complement(10001..10738)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033537.1"
                     /locus_tag="GCN81_RS05650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_156722316.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.1e-10,
                     bitscore: 35.3, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF13471 (E-value: 5.7e-20, bitscore: 66.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGLQIPKHVHVGDAFHGGQVLFDARSGQWYAMNGTARLLWEEWH
                     RTGDFESAVRTLADGFPCVRYDSVRLDAERVARDLVERGLVYLDEERGSAHRDLPHGST
                     GLVSPDVSRTWDANTVRWPRTASLIGLLLALCLLRFPFRACVHAVTVLKERCGRRPATT
                     RQAEVMLTAVRRAGERYPGRVACLEDSLATVLGLAVAGLAADWCLGSADDPYRFHAWVE
                     VAGATVEPAEADDHTRFRRVLVL"
     aSDomain        complement(10481..10693)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_GCN81_RS05650_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="1.40E-11"
                     /identifier="RREFam002.1"
                     /label="GCN81_RS05650"
                     /locus_tag="GCN81_RS05650"
                     /protein_end="86"
                     /protein_start="15"
                     /score="35.3"
                     /tool="antismash"
                     /translation="FHGGQVLFDARSGQWYAMNGTARLLWEEWHRTGDFESAVRTLADG
                     FPCVRYDSVRLDAERVARDLVERGLV"
     gene            complement(10783..12639)
                     /locus_tag="GCN81_RS05655"
     CDS             complement(10783..12639)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.5"
                     /locus_tag="GCN81_RS05655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_156722317.1"
                     /sec_met_domain="Asn_synthase (E-value: 2.8e-31, bitscore:
                     104.2, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRALSTADSIDMWCHREFTGVFPPLADSAPPLVVGDAGLAPPHGT
                     VLRTMGRWREGELRSFQCAGGSVIAVGQCLAGEQEFTRDADRALATGRLLPLTQWTGSY
                     LCLVVRPHELTAFADLAGQYPLYFRRRPGRTWIGSQPATVAAAAGGGCRPDLQTLATQV
                     LCPDVPLLPQNRSVVADVEQLGSGQALRITTEGACTQWEYETLLPDTDASFATGAEALR
                     TALEESVGRRAARAGALTADFSGGLDSTSLAFLALRHKAGPLPVFTYHRAGGDCDDVEH
                     AHRFARLDQRLHLQDVAGTPETLPYQRMEGVRRTGEPDPAAVGTARTRLRLEHIARHGG
                     DIHLGGEGGDALLSAPPCYLAGLVRLGGLRKLGRHSHVLARSRHVSPLEVMGRAAHLAH
                     TSFATALHRTARLLEQPEATVPHWLDTVSWWLAPGPEIAWLTDSARKEVAKLARSRIPI
                     PPDPASTQPDVHATRHQLRTSASAQRQLDHTAAPFGLWPQAPFLDNDVIRACLRLPAHL
                     RADPPAFKPLLGAALSGAVPAPVLDRRTKGDYSGEDYQGIRLASTALREILDTSRLAGF
                     GVIAPDVVATSLDRARMGLRAPFPALNRLLGVELWLRSTLWR"
     misc_feature    complement(11848..11850)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(12019..12021)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12669..12881)
                     /locus_tag="GCN81_RS32945"
     CDS             complement(12669..12881)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033521.1"
                     /locus_tag="GCN81_RS32945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso RiPP family leader peptide-containing
                     protein"
                     /protein_id="WP_156722318.1"
                     /transl_table=11
                     /translation="MTMLRKHANQSTRPSVRDTAAPSASEDFDGAHPPLEAYDPPTVVD
                     LGHVREVTLGSSSSGNADANSHYYW"
     misc_feature    12962..12979
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.11"
                     /tool="antismash"
     misc_feature    complement(13193..13206)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.73"
                     /tool="antismash"
     gene            complement(13252..14409)
                     /locus_tag="GCN81_RS05665"
     CDS             complement(13252..14409)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF012692.5"
                     /locus_tag="GCN81_RS05665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ROK family protein"
                     /protein_id="WP_197287487.1"
                     /transl_table=11
                     /translation="MLISIMIKGDTQANLARRTGLAQSTVSNIVGELQTAGVLPNDKAE
                     QARAVRRGTVRLPPTRNVAVGVHLGFVRATVVARRVDRPISETHSEHVASGANRGMSEV
                     IPVLKQAIREAVGRTSLGLEDVVSLGVAVPRMVDPRTGRFASPILPPWSEGDDPSRDLG
                     AWLGVPGALDNDANLGALAEQTYATDGHAEIVVYIKGSTGIGAGLVISNTPIRGRGMAG
                     EIGHLVFDPNGAVCRCGGRGCLETVIGANALVRQARDALSGSAVDVPHSLASLIEKAQA
                     GDVVCERIMRDAGRVLGQALAQLCNLLNPDLIVVGGTLGAAQGMVLDPCQESLERFALR
                     GAVGPHSGFTLKSSSMNQLSEAQGALLLGLTSLRRSDDTQEQGRD"
     misc_feature    complement(14387..14400)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.76"
                     /tool="antismash"
     misc_feature    14528..14542
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.8"
                     /tool="antismash"
     gene            complement(14769..15119)
                     /locus_tag="GCN81_RS05670"
     CDS             complement(14769..15119)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GCN81_RS05670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_156722320.1"
                     /transl_table=11
                     /translation="MTGTGLVTAQREVDGETNEITAHGRDEIGWIKAADVTGIVFPHAV
                     QAVRRQRIVTTGKVALERVCGVTDLTAEQAHRPSPTRRTSEHRRWTPPPHPQRQLSTDH
                     SRHHVIPHGHVT"
     gene            complement(15554..17023)
                     /locus_tag="GCN81_RS05675"
     CDS             complement(15554..17023)
                     /GO_function="GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018530682.1"
                     /locus_tag="GCN81_RS05675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="WP_407697937.1"
                     /transl_table=11
                     /translation="MAETPRVRKAAAVPEDERADDQVPTPHPVDEKLPPLKMMTSGLQH
                     VAAMYAGVVAPPLIVGAAVGLSGKELTFLTGASLFTAGLATLLQTLGVWNIGARLPFVN
                     GVTFAGVAPMLAIVDQTQSAGNADDALPIIFGAIIVAGLLGFIGAPFFSKLVRFFPPVV
                     TGTVITLIGVSLMPVAFGWAQGPDPAGDDYGAMKYLGLAAITLVIVLLIRRFTSGFVKQ
                     IAVLLGLVIGTVVAIPFGVADFSAVGEASVVGFPSPFHFGAPQFAVAAIVSMVVVMIVS
                     MTESTADMLALGEIVERPADEKTIAAGLRADCLGSALSPLFNGFMCSAFAQNIGLVAMT
                     KIRSRFVVAVGGGFLILMGLMPVVASLIATVPRPVLGGAGVVLFGSVAASGIQTLAKAG
                     LEKDNNVLIVAVAMAVGLIPIAAPEFYHAFPDTAMIILDSGISTGCVAAVVLNLVFNHI
                     GKRRDDDDVTAPMEPGEEISESRVPSARAGH"
     gene            complement(17327..18703)
                     /locus_tag="GCN81_RS05680"
     CDS             complement(17327..18703)
                     /EC_number="3.5.4.32"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018491518.1"
                     /locus_tag="GCN81_RS05680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="8-oxoguanine deaminase"
                     /protein_id="WP_156722321.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 3.2e-63, bitscore:
                     208.7, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAASRIVIENCAIATVDADDTEYASGYVVVADNRIEAVGAGTAPA
                     HLENVVRRIDGTGHLLTPGLVNTHHHFYQWITRGLATDHNLFNWLVALYPTWARIDASM
                     AKAAAQGSLAMMARGGVTTAMDHHYVYPRGSGDLSGAIIGAARDMGVRFTLARGSMDRG
                     EKDGGLPPDFAVETLDGALAATAETVDQHHDASFDSMTQVAVAPCSPFSVSTELMKQGA
                     ELARAKGVRLHTHGSETVEEEKFCHELFGMGPTDYFESTGWLGEDVWMAHCVHMNDSDI
                     AAFARTKTGVAHCPSSNARLAAGIARVPDMLKSGVPVGLGVDGTASNESGELHTELRNA
                     LLINRLGAHREAALNARQALRLGTFGGAQVLGRAEQIGSIEAGKLADFVLWKVDGIGHS
                     SIADPVTALVFGAAAPVTASFVNGQQIVEHNRLLTADEDAIARVARDEAQRLARIAAAD
                     "
     gene            complement(18841..19764)
                     /gene="pucL"
                     /locus_tag="GCN81_RS05685"
     CDS             complement(18841..19764)
                     /EC_number="1.7.3.3"
                     /GO_function="GO:0004846 - urate oxidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0019628 - urate catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pucL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018514695.1"
                     /locus_tag="GCN81_RS05685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="factor-independent urate hydroxylase"
                     /protein_id="WP_156722322.1"
                     /transl_table=11
                     /translation="MPTILGQNQYGKAENRVVKITRDGDTHHIKDLNVSVALSGDLDDV
                     HYSGSNAHCLPTDTTKNTVYAFAKEYGIESAEQFGIHLARHFVTSQEPIHRARIRIEEY
                     AWDRIATADANSKFIGSDEVNHSFVRQGQETRVTQITYDGEKWEVVSGLKDLVVMNSTN
                     SEFWGYIKDRYTTLKEAYDRILATQVSGRWRFNWSDDEQRMPNWEKSYEQVKKHMLQAF
                     AETYSLSLQQTLYQMGSRIINHRSEIDEVRFSLPNKHHFLVDLEPFGLKNDNEVYYAAD
                     RPYGLIEATILRDGVEPKIPVDLTNL"
     gene            complement(19770..20180)
                     /gene="uraH"
                     /locus_tag="GCN81_RS05690"
     CDS             complement(19770..20180)
                     /EC_number="3.5.2.17"
                     /GO_function="GO:0033971 - hydroxyisourate hydrolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006144 - purine nucleobase metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="uraH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015612348.1"
                     /locus_tag="GCN81_RS05690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hydroxyisourate hydrolase"
                     /protein_id="WP_156722323.1"
                     /transl_table=11
                     /translation="MSTDTTASVSTHILDTSIGRPAEAVAISLAARSGSDQEWVTLGGS
                     ATDADGRCKDLPALPEGITHVRLDFETEAYFAHQPQHHANQQAEAQQDAPRVRDSGAFF
                     PEVAITFAVKPGEHYHVPLLLNPFGYSVYRGS"
     gene            complement(20177..20713)
                     /gene="uraD"
                     /locus_tag="GCN81_RS05695"
     CDS             complement(20177..20713)
                     /EC_number="4.1.1.97"
                     /GO_process="GO:0019628 - urate catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="uraD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016638552.1"
                     /locus_tag="GCN81_RS05695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline
                     decarboxylase"
                     /protein_id="WP_156722324.1"
                     /transl_table=11
                     /translation="MTSGTTPGLTRFNALEETAAAAELHEVCASSAWGSKLLAQRPYAT
                     VESLFAASDAAMAELTTADLEEAMAGHPPIGRPKPGDPTSSREQRGMAGASEELKRELL
                     ELNLAYQDKFGHVFLICATGATGEQMLAALKARIENTAEQERAIVRTELGKINRIRLTR
                     LVEQRSAEQQEEGNR"
     gene            complement(20904..21281)
                     /locus_tag="GCN81_RS05700"
     CDS             complement(20904..21281)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015579367.1"
                     /locus_tag="GCN81_RS05700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_156722325.1"
                     /transl_table=11
                     /translation="MTEPRDHPFVTAVKPLVDAMGGELLSPQEADGDDVVLAWEGEDVL
                     AVRLPQLADSLDRILAALERKHGRPLSELDRKAKQEVVRILEGRGAFSVRHGVETVAGA
                     LGVSRFTVYNYLNRENAAKGE"
     gene            complement(21278..21532)
                     /locus_tag="GCN81_RS05705"
     CDS             complement(21278..21532)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003993971.1"
                     /locus_tag="GCN81_RS05705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_156722326.1"
                     /transl_table=11
                     /translation="MRLRVEFTTEPFDLEEAPTHAVVARDVIQAAELDAVDVGPFGNTA
                     EGGADAVLTAVDALLRKSLAAGATRVSLQVNVVGEEEGR"
     gene            21656..22495
                     /locus_tag="GCN81_RS05710"
     CDS             21656..22495
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009191359.1"
                     /locus_tag="GCN81_RS05710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TIM barrel protein"
                     /protein_id="WP_156722327.1"
                     /transl_table=11
                     /translation="MGFTDQRFNVNLSILYTELPLLERPAAAAAAGFTAVELWWPWVDS
                     PTPAQSELDALKSALEDAGVQLVGLNFYAGQLPGPDRGALSIPGEESEKFRANIDIAAD
                     FAASVGCKALNALYGNRVEGVDPAEQDALALENLQIAARAAHRVGAILLIEALNKPESP
                     LCPIVSAPKAIEVVDAVNAATGLGNAKFLMDLYHLSMNGENLPEVIEKYTAKTGHVQIA
                     DNPGRGAPGTGDLPLEDLLDQLKKAGYDGWVGLEYKAGDQSSTESFGWLPAEARAAR"
ORIGIN
        1 gaccccgccg acgccagcta caccctggcc agcgccggac acccaccacc gctgctggtg
       61 gccccggacg gcacgccgtc gtacgtgccg gtgccgaccg gagcgccgct gggcgccggg
      121 gtcatcccgt acgacccgct ccggttgccg gggccggtgg gcagcaggct ggtcctctac
      181 acggatgggc tggtcaagac ccgtatccct accgacgacg tggacatcca actggaccgg
      241 ttgcggaagc aggccgcggg gatggcgccg gagcggctgg acgactgcga actcctcgcc
      301 tccgcggtgg agggcgaggg ccgtttcgac gaggccgtgc tgctcgtcgc ggcgggcacc
      361 cgagcggagg acatcgcgct tcaggtgtgg gacctccccg caggcggacc cgcggcctcc
      421 accgcgcgca aactggtcag ggaacagctc cagctctggg gcctgaccga gctggcggac
      481 gtcaccgaac tggtcgtcag cgaactggtc ggcaacgccc tccggtacgg gggcgggggc
      541 cctggacagc tgcggctgct ccgcgacgag cgtctcgtcg tggaggtctc ggacaccggc
      601 ccggacctgc cacgcatcca gcacgcggac gtctgcgacg agggcggtcg cgggctacag
      661 ctgatcaaca tgctgtgccg cagatggggt tcctgccgca ccgccacggg caaggtcgtc
      721 tgggcggagc agaacatccc tggcagctga gagcccgtcc gctgtcttcg taccctgccc
      781 gttgtccttt ccaccctgcc cgtcgccgac agccggagcg cggagtcgct cagctcgcgc
      841 cgcgcgccgc cttccactcg ggggcgagga ccgaccagat ctcggtgtcc tggcgtatgc
      901 cacggtaggg gtcgttctca cggaggacgc cctcgcgggt catgcccagg cgcttggcca
      961 ggttgatgct cggggtgttc ttggaggaca cctgccactc cacgcggtgc atgccgcgct
     1021 cctcgaccgc ccagtcgatg aggacgcgta ccgcgcgggt gaccaggccc tggcccgccg
     1081 cgtccggctc cacccagcag cccgcctcac aggtgcccct acacgcgtcg aagacccgga
     1141 acaggacacc accgacgagc agcccgtcga gccatatgcc gtacagtcgg ccggcgtcgg
     1201 cggcggcctt gtcggcgtag acctggagcc atctgcgcgt ggcgtcgagg ttggacgtga
     1261 cgtcggggag tccgacgtac tgtccgatga agtcgcggcc gcggtccatg tgggcgagga
     1321 actcctcggc ctgccatggc tccagtggcc gcagctcagc tccgttaccc agcgaaacag
     1381 cgaacattct caccctccag gacggtcgtg ctcggtcggt gacccagatc tctcgatctt
     1441 tgcatggccg tctgacagtc ggggttggcg ggttgtccgg atcagtaccc cctcggcgtc
     1501 cgtggtcttg tgccgggagt gtggtggcct cacactctcg ctgcccatag cgcacaggcg
     1561 caccacggca gaggggacct ctggcatgcg acgaatacgg gtgggtgtgc ggcgtcgagt
     1621 tgtcgtcgcc gtagcgctgg cggccgcgct ggggctcggt cttggtgccg ttccggcggc
     1681 gggcgccgag ggattggcgt cagccgatgc ggagggatac gccgatgcgg agggatacat
     1741 cgtcacgttt gacggctcag gcgtgcggct cagctccgcg tcccaggacg cccgttccct
     1801 ggtcgcccgg tccggcgcgg tcatcaaccg tacgtaccgc accgcgctca acggcttcgc
     1861 cgtcaccgcg actcggcagc aggcagcgcg gctggccgcc gaccccgccg tgcgttccgt
     1921 cgtacgggac accccggtcg cggccctcgg cgtacagacc gacccgccct ggaacctgga
     1981 ccgtatcgac caggagaggc tgccgctcga cgggctgtac cgctacccgg actcggcggg
     2041 ccggggggtg acggcgtacg tcctggacac cggggtacgg atcacccacc gcgagttcgg
     2101 cgggcgcgcg gcatacggcg tcgacaccgt cgacggggac gacaccgcac aggacggcaa
     2161 cgggcacggt acgcatgtcg cggggatcat cgccgggcgc aagtacggcg tcgcgaagaa
     2221 ggcgcgggtg gtggccgtac gggtactcaa tgacagtggg ggtggtacgg cctccggcgt
     2281 catcgcgggc atcgactggg tgacccggca cgcgtccggg ccgtcggtgg ccaacatgag
     2341 cctgggcggg cccgccaacg aggcgctgga cgaggccgta cgcaactcgg tcgccgcggg
     2401 catcacgtac gcggtggctg ccgggaactc gaacaccgac gccggacggt tctcgccagc
     2461 gcgggtggcc gaggcgctga ccgtgagctc gactgacgcg ggtgacgtgc gggccagttc
     2521 ggccaactac gggaccgcga tcgatctgtt cgcaccgggg cggaacatca cctcggcgtg
     2581 gaacacgtcc gactgcgcgc tcgccacgct gtccggtacg tccatggccg ccgcgcaggt
     2641 gaccggcgcg gccgcgctcc agctcggcga gagcccgtac gacagcccag cgcgggtggc
     2701 caagtccctt accgaggggg cgagtggagg ggtcgtcagt ggcccggggg cgggttctcc
     2761 gaaccggctg ctgaacgtgg gcgggatcgg aactcggtaa ccccgtccgt ggctctgctc
     2821 actttcgccc ccgtaggcac aggcgtacga ccgcactgtc ggtcgcagcc gctacgctgc
     2881 ccgcgtgcag cgaacagagc gtgagtgtca gcaagcggat cgacaagaga agcagcaggt
     2941 catgaggcgt aggcgacggg ggtggtggct ggggtgcgtg gcggtcggcg cgctgatagc
     3001 cacctccgga tgcggcctcg tcgaaagcaa cccggagccc gacggatcag cgccccccac
     3061 cgctgaggcg agcggcggca cggacgacac aggcggcggc acgggcggca cggacagccc
     3121 cggcgacggc aagcccgccg ccgaaggcac cctgccgaac gtgccgaccg tcgaggccgc
     3181 ccgcacccag ttggccggac tgaaggtcgc cccgcacggt tcgatgagcg gctacagtcg
     3241 gtcctccttc tcgcactggg cgcagcaggg cgacaagtgc gacagccgtg aggtcgtcct
     3301 ggagcgggac ggcaaggacg tgcagcggga cgacgagtgc aaggccgtgt ccgggacctg
     3361 ggtcagcgcc ttcgacgggg tgacgctgga ctccgcctcg aaggtcgaca tcgaccacat
     3421 cgtgccgctc gccaacgcct ggcgttccgg ggcggcccgc tgggacgccg acaagcgcaa
     3481 ggccttcgcc aacgatctgg agcagcccca gctgatcgcg gcgtcggcgt cctcgaaccg
     3541 ctccaagggt gaccaggggc cggatgagtg gcagcccccg gagaagtcgt actggtgcac
     3601 gtacgggcgg gcgtggacgg cggtgaagtc gtcatacgag ctgtcggtca ccgagtcgga
     3661 gaagggcatg ttgaaggaca tgctggacac ttgtgagtca tgagcgacag cacgagcgcg
     3721 tcaccaggtc cggtccccag cgcggatgac atcgccgcca tcgccccgct cgtcggccag
     3781 gtggtggccg ggcccggtgg ggcgatgacc gacgaggtcg gggtcatcac cggggatatc
     3841 accgtggcga ccgcccccct gcccgacggc cgggcggtgg tggccgtcca gtacaccgac
     3901 gccgacgagt ggtacctgct gagcggcggt ccggtgcccg taccggccgg tgggcttgat
     3961 gagctccacc acgaggtgct ggagctcatc aagaagggcg gcggcgccga agtcccccgg
     4021 tgacgcaccc ggtgactcag ccgtggcgtt cgacgcgtag ctgggccggt ggggaggagt
     4081 acgtcgagtt cgcgcccacc gcccagtagc cactggccgt tcctgggatc gcggtgatcg
     4141 cgttcatgag ggaggtcgag ccggtggcct cgggtccgcg ttcgctggtc cagtctgagc
     4201 cgttccagcg caggtagtgg gtgcgcttct ggtcccagaa gtcccagccc gcgatgaggt
     4261 ccgggcgccc ctgggcgtcg ccgatgatgc cgctcagcac gcctacggtg aacggggatt
     4321 cacccctggt ccattcgccg ccgtcccagc gctggaacgt gactcccggg ggcttgccgg
     4381 gcggaccgcc gggtccgtac gcgtagccgg tgagccagat gtcgtcgtgg gcgacgggga
     4441 gcagtccggt gacgccggag cggatgccga cgtgccgggg aatgacggtc caggcgccat
     4501 cccagcgggc gatgacgtcg ccgtagaccc agacctcccc gcagggcgtg acgtgtacgc
     4561 cgtacggtgt cggggtcgcc tcgtccggga gggggcggca ccagcgccac gcggggccgt
     4621 tgccgggtcc gggtccgcgc atcagtccgg cccggtcgcc gtggcggccg ctgacccagg
     4681 cctggccgtc gccgccaacg gccacatcgg tgaggcgggt gcctggctcg cctcggccgg
     4741 ggaagttcac ctcctgccag gtttcgccgt cccaggccag gagttggtcg ttgccgtcgg
     4801 tgttcgtgcc gagcgcccag gccgcgtcgg cggagctgtt ggcgaccgcg cggagcgccc
     4861 cggtgtagtc gaggtgggtg aggtcggtac gggaccaggc cgtgccgttc caggcgaggg
     4921 ctaaagggcg gccgcgggtg ctgcgggatc ggccctcgtc gcccacggcg aaggctatgg
     4981 ctggcccggc tgcggccacc ccgacgaggc gggcggcctc ctcgccgggt ggtgcgggga
     5041 cttcgcgcca ggtttccgcg gcgttggtgg ggcgctgaag cgcggcggcg gtagcggcgg
     5101 ccgcggtggt ggtactggcg gcggcgagac ccacgcccgc cgcggtgccg gtgagtccgc
     5161 tgatgaagtg tcgtcttcgc acggaggtgc ccttcttccg tgggatggaa ggcaccaccc
     5221 tggaccagac caccggggga ggcaatggac gcgcgtgagc acttcggcgt tgtcagtggt
     5281 gggccgcact atgggaagta cggggtgttg gggcgaaggg agcggcggat gaacgggcta
     5341 ggcgactcga gtcgtgctgg tagcggccgt gcgccgatgg cggggcgggc caccgcggcg
     5401 cagcggcgga tcatcagtgc ggctgaggcg gtgacggggc ggatcgtggg cagcgaggcc
     5461 cagttggagg gcctggtgcg ccgagggctc gcctttcggc atccgcgccc gccgcgggcg
     5521 tacttcctca cccctgcggg ccatcgcctc cgcgacgagc tgctggccgc gacgccccca
     5581 ccgcccgccc cggtgaccga cgcggcgacg ggggtgttca cggcgcgcac cggcggtgag
     5641 ggcgatcccg tcgccgggcc agggcggcag cgtgaggtgc acagtgcctg gcaggggctg
     5701 cttgagctgc gccggatgac ccgtccggac ggggacacgg ggcggccctg cgggtgggag
     5761 cgcacgcact tggtgcaggc cgccgcgctg gcgctggagg cggcggggtg catgcccgcc
     5821 ggggcggagg acaccggtgg cgggtaccgg gtcgcggaga gcccgcagcc cgaggcggtc
     5881 gcggtacggc tgatacccgg tggcggcggc atggacgacg acggcctcgg tggcctcggc
     5941 ggctgtgcgg ccgcgctgga ggcggcgggt tggcaggtca gcgagcacca ggagcggggc
     6001 gggggccgct gtctgctcgc ctcaccccgg cgcgactgag acaggccctg accagcggtc
     6061 aggtcaggcc tggcccgtct cgaagcggct gacctttccg tccgagaccg tgaagtgcca
     6121 tcgggtgcgc atctcgcccc aggtgtcgtt gcggtattgg gcgacgaggg tgcggccgcc
     6181 gtcgctctcg gactcgacgt ccatatggcc tccggcggag aagatctcct tctcggtcca
     6241 ctcggcgagg ttacggtccg agccgtcgtc ggacatggtg gcgtcggggg tgagcgctgc
     6301 caggaaggcg gtgcggtcgt tcgcgttcag ggcggtgacc agggcgcgga cggccgggtc
     6361 ggagagcttt tcggtgggga tcacgagcgt tcctcttcac ggttcgtggt agcgacggcg
     6421 gtctgtctcc cgatcatgtc ccgcacgcgg cggtctcgca tcctgggccc gccgtactgg
     6481 acggcggcac tcggcggcgc gaatccggcg cgatgcgtct cgcgattttt gatgtgccgt
     6541 caaaggtcaa taagatccgg cgatgatcac aagaaaacgg ctggcggcgg gcgcatgcac
     6601 cctgctcgcc gccctgacgg ccgggctgct ccccgcggcc accggcaccg ccttcgcgga
     6661 cgaccccagg ggcggtgacg gccccgcccc gaaggtcgaa ctcgtcctcg atgtgagcgg
     6721 gtcgatgcgg gcccgcgaca tggacggcgg gtcgcggatg gccgccgcca agcaggcgtt
     6781 caacgaagta ctggacgcga caccggacga ggtcgagctc ggcatacgta cgctcggcgc
     6841 caactaccgt ggcgacgacc gcaaggaggg ctgcaaggac accgcgcagc tctacccggt
     6901 cggcgtcctc agcaaatccg cgcgcaccga ggccaagacc gcggtggcca cgctcgcgcc
     6961 caccgggtgg acgccgatcg ggcccgcgct gctcaaggcc gccgacgatc tcgaaggcgg
     7021 cgacgaggcc accagccgca ggatcgtact catcaccgac ggtgaggaca cctgcgcccc
     7081 gctcgacccc tgcgaggtgg cccgcgacat cgccgcgaag ggcatcaacc tcaccatcga
     7141 caccctcggc ctggtcccgg acgccaagac ccgcgaccag ctgagctgta tcgccgacgc
     7201 gacaggtggg acgtacagct cgatccgcca caaggacgaa ctctccgacc gggtcaacca
     7261 gttggtggac cgggcggcgg agccagtgat cacgccggtc gccgtggagg gcgcggacca
     7321 gtgtgcgaag gcccccaaga tcggttcggg gctctacacc gaccgggaga agttcggtga
     7381 gcaccgctgg taccaggtcg atgtcaagcc gggtcaggag ctgcgcgcct cggtgagcgt
     7441 ggcggcggac cgtcaggtgg acaacgacta cggcgtactg ctgcgcgcca caaccgtgca
     7501 cgggcgtgag atcgtacgcg gcgagtcggc gggcagtggg cgcaccgacg tcatctcggc
     7561 ggggctgcgc tacccgaagg cggacagcga ggacaccgat gacgccgacg gtgcgggcga
     7621 gccggagacg gtctgcctgc gggtcagcaa ctccttctcc gctccggctt ccgtcaagcg
     7681 ggagcccggg ctgcccgtgg agctgacgat cgacctggtg gacggcccgt cggacgcctc
     7741 cgacgtggcg ttcttcggcc tgggccgggg ctggtggctg ctcggcgcac tggctgtggc
     7801 gggattcctg ggcggtgtgc tgtggggctg gctggcccgc tggcgtggcg ctgtgacgag
     7861 gagcaactga tggggatcac caaggcgttg cgggtcggcg tcagtgcggc actgctggcc
     7921 ggtacggcgc tgttcggcgc ggcggggacg gcgtgggccg atgacccgtc cagcagccca
     7981 agcgcggacg gcgacagcgg ggacggcggc agcgacagca acggtgggga cgggcccact
     8041 gaggcgggta cgtcgttccg taccgccgtc ggattcgagc cggggcagcg ggccaccgct
     8101 gccgcgtcca ccggcgagta cctgtactgg aagttcctgg ccgacaccgg gcagcgcccc
     8161 acggtcaagg cgaccgtgaa gctcccggag ccgagcgccc gcaagggcac ccagacctgg
     8221 caggtcgacg tgtacgacgg gctgcgccgc cgccaggcct gtatgtacgg cgcgcagacc
     8281 cgcaaggcgg cccagaacgc cgagtccgtc tcgctgtcct gcacgctgcg tcccgtacgg
     8341 gcctggtcgg agcagtggtc cgatgacccg ctgccgggca cgtactacgt gcggctcacg
     8401 gtcaccgggc tcaaggcgac ggacctgggt ctgccggtac aggccgaggt cgagacgacg
     8461 ttcaaggacg tgggtggctc gcacgcggtg gacggctcgc tggcggcgcc gctcgtggcg
     8521 ggcaacggag acgcggcgga cgccgactcc gggcccggct ccgggtccga cagcgggtcc
     8581 gggaacagct cagcgcggca ggccgctgcc gccgccgagc ccgaggacgg ctgggcgtcc
     8641 ggctggtggt cggaccgctg gctctggaca gcggcgggcg gcttcgtcgc ggcgttgacc
     8701 ggcgtgggcg gatactgcct ggcgcgcggt ccaggccgcc ctcgcgcgta gacgaacgcc
     8761 ccgggtgccc ggtccgcctg gcacccgggg gctgaagggc cggccagcgg acgactccct
     8821 ggcggtgtga ggaacggccc cgctcgcgca gttcctcttc ccctacctag cccatctgaa
     8881 gtccgacccc ggtcagcgaa cctgatcagc cgaccctgca cgtcgtcgac ctttcgacgg
     8941 ctctgggcaa cgggcgatcg tccgccgccc aaacggtcgg cacccgttcg ccaacgcgtc
     9001 gtcatccacc ggttacttga caacgtcgac gagattcttt gccgcgtctt cggtgcatcg
     9061 ccgatggccg attcgacgcc gccaccgact ggtgaggcct gtggcggcgt tcaatccgaa
     9121 tccttggact cccgccagcg gcagaggtgt tcggtttgat cccgaagccc gtgcggagcc
     9181 ccgcacggcg ctgcgggagc acactgtccg ccgcgtcggg tcacgcacta cgcgtttcct
     9241 tcgattcagt cacctggttc gccatcccgg gcacatcgtg gacgaattgc agacgacttc
     9301 gacctaatat gcttctttca cctctggcat gcggtgcagg tgtcgcggag ggtacgttgc
     9361 aaggccttgc caggcgaaga aatacggaag aaaatgcttc tggggcgtcg ctttcgatct
     9421 tctgctgtca ggcatgagaa tcagctcaca aacagtgaaa aacgccctct ccggcggttg
     9481 ccgcggagcc cgttccggcc cctactcctc gaaaggaggc tctcagtgaa cgtgaaagct
     9541 cagatgacga tcaagggctc cacaagtctg acctggataa gcgtccaggt gatcgtgatc
     9601 gtcatcgtcg tgctctctgc gaacagctac cttgcctgcc tggtcaggta gttcaaggag
     9661 cattgagggc cgtccgtagc agcgggcggc ccttcaggtt gcgccgacct tttacttacc
     9721 gggtaagtgt agcggcctac cccgccccga gagaacccgc ttgggggatt gttttacgaa
     9781 accgatcggt aagaacgccc cagacgggca gcgtgaggga attcgaagaa atcttacgca
     9841 tgtcgcgtcc tcggactcga tgggagcgct ctcgtgatcg atgtcagatc gtggtcaacg
     9901 tgcggacggg aaaacgaaag ctgggatgtg tttcagcgtg gaacgttctt cattttggag
     9961 gtgtgagacc ggtgtagcag gtggtggccg gtccccctgc tcatagcacc agcacccgtc
    10021 ggaaacgggt gtggtcatcg gcctcggcag gctccaccgt cgcgccggcg acctcgaccc
    10081 aagcatggaa tcggtaagga tcatcagcac tgccaagaca ccaatcggcc gcgagcccgg
    10141 ccactgcgag gccaagcaca gtggccagtg agtcctccag gcaggcgacg cgccccgggt
    10201 agcgttctcc ggcccgtcgg acggctgtca gcatcacttc agcctgtcgc gtcgtggccg
    10261 gtcgccgccc acagcgctcc ttgagcaccg tcacggcgtg cacacaggca cggaagggga
    10321 accgcaggag acacagcgca aggagcaggc caatcaagct cgcggttctc ggccaccgga
    10381 cggtgtttgc gtcccatgta cgggatacgt ccggactgac gagccctgtc gagccgtgcg
    10441 gcaggtccct atgggcggag ccgcgctctt catccagata cacgaggccg cgctcaacga
    10501 ggtctctggc gactctctcg gcgtcaagcc gcacggagtc gtagcgcaca caggggaacc
    10561 cgtcagccag ggttcgtaca gcggactcga aatcaccggt gcggtgccac tcctcccaga
    10621 gcaaacgcgc ggtgccgttc atcgcgtacc actgaccgga ccgtgcgtcg aagagcacct
    10681 gcccaccgtg gaaggcatcg ccgacatgaa cgtgcttggg gatctgcaag ccggtcatca
    10741 gatgcctctt tctacggcga aacggcgagg taggtgcacg attcagcgcc agagtgtgct
    10801 tcgtagccac agctcgacgc caagaagccg attcagcgcg ggaaaagggg cgcgaagccc
    10861 catccgcgcg cggtccagcg aggttgcgac cacgtcgggg gcgatcacac cgaagcccgc
    10921 caggcgcgag gtgtcgagaa tttcacgcag agcggtcgag gcgaggcgga tgccctggta
    10981 gtcctcaccg gagtagtcgc ccttggttcg gcggtccagc acgggggcgg gaaccgcgcc
    11041 cgacagcgct gcgccgagca gtggtttgaa ggcaggagga tcagcacgta ggtgggcggg
    11101 caaccgcaaa cacgcccgga tgacgtcgtt gtcgaggaac ggggcttgcg gccagagccc
    11161 gaaaggcgcg gcggtatggt cgagttgacg ttgcgcggag gccgatgtgc gcagttggtg
    11221 ccgcgttgcg tgtacgtccg gctgggtact agcgggatcg ggagggatgg ggattcgcga
    11281 acgggccaac ttcgcgactt ccttccgtgc ggagtccgtg agccaggcga tctccgggcc
    11341 tggggcgagc caccagctca ctgtgtccag ccagtgaggg acggtcgcct caggctgctc
    11401 cagcagcctc gccgtacgat gcagagcagt cgcgaacgat gtgtgcgcca gatgcgccgc
    11461 ccggcccatc acctcaaggg gcgacacatg acgcgatcgt gcgagaacgt ggctgtgccg
    11521 accgagtttc cgcaagccgc cgagccgtac caggccggcc aggtagcagg gcggcgccga
    11581 caggagcgcg tcgccgccct cgccaccgag gtggatgtct ccaccgtgcc gcgcgatgtg
    11641 ctccaggcgg agccgagtac gagccgttcc cacggctgcg gggtcgggct ccccggtgcg
    11701 ccgcactccc tccatccgct ggtagggcaa ggtttcgggg gtcccggcga cgtcctgcag
    11761 gtggaggcgt tgatcgagcc gcgcaaatcg gtgtgcgtgt tccacgtcgt cgcaatcgcc
    11821 tcccgcccga tggtaggtga acacgggtaa gggccccgcc ttatgacgga gcgccagaaa
    11881 agcgagcgaa gtggaatcca ggccgccgct gaagtccgcg gtcagggctc cggcgcgggc
    11941 ggcccgccgc cctaccgatt cctcgagtgc cgttctcaga gcctcagcgc ctgttgcgaa
    12001 cgaagcgtcc gtgtcgggta agagcgtctc gtactcccac tgagtacacg cgccttccgt
    12061 ggtgatccgc aaggcctggc cgctgccgag ttgttcgaca tcggccacga ccgatctatt
    12121 ctggggcaac aggggtacat cggggcagag gacttgagtc gccagggtct ggagatccgg
    12181 gcggcatccg ccgccagccg ccgcggcgac tgtcgcgggc tgtgagccga tccaggtgcg
    12241 gcctgggcgg cggcggaagt acagcgggta ctgtccggcc aggtccgcga aggctgtgag
    12301 ctcatgcggg cgcaccacga gacacaggta gctgccggtc cactgggtca gcggaagcaa
    12361 ccggcccgtg gccagggccc ggtcggcgtc tcttgtgaac tcctgctccc cggcaagaca
    12421 ctggcccacg gcgatgacgg aacccccggc gcactggaag ctccgcagtt cgccttccct
    12481 ccaccgcccc atcgtgcgca ggaccgtccc gtgagggggc gcgaggcccg catcgcctac
    12541 gaccagtggg ggtgctgagt cggccagcgg tgggaagaca ccggtgaatt cccgatgaca
    12601 ccacatgtcg atgctgtcag cagtgctcag agcacgcatt ccgtctcctg tccgggtagc
    12661 gtctccgctc accagtagta gtgggagttg gcgtcagcgt tgccgctact ggagcttccg
    12721 agggtcacct cccggacatg tccgagatcc accaccgtcg gcggatcata ggcttcgaga
    12781 ggcgggtgag ccccgtcgaa gtcttctgag gcggagggag cggcagtatc gcggacggac
    12841 ggtcgagtcg actggttggc gtgtttcctc agcattgtca tatacccatc cggagtcggc
    12901 cctaaaggca cgcgtaatcg aatgaaccga acatgattga tcagtgccag gtattcgact
    12961 ttagccgtta ctgcggctac gggcccctgt ggcgctagat atcggccgct cacgatggca
    13021 ggaggcgggg gcagttgtcc acacggatgg gcgggtggtg gacgaggaga tgagcaagag
    13081 agagtcgctg gcgcgcagga attctccggc gccgacagta aatcgcaact ttcgctgggt
    13141 gaagggagct tccgctgttc agactgaaga agaaggtgtc gggtgaagca tggcaacgtt
    13201 catgcctgac cgttgatcaa gtggttcgcc cactgagcaa caggcgttcc ctcagtccct
    13261 gccctgctcc tgggtgtcgt ctgacctgcg aagggacgtc aaacccagca acaaggcccc
    13321 ttgcgcctcg gacagttggt tcatcgaact cgacttcagc gtgaatccgc tgtggggacc
    13381 gaccgcgccg cgcaacgcga aacgctccag ggattcctgg caaggatcga ggaccatgcc
    13441 ttgagcggca ccgagcgtcc ctccgacgac gatcaggtcg ggattcagaa ggttgcacag
    13501 ctgcgcgaga gcctgaccga gcacccgccc ggcgtcgcgc atgatccgct cgcaaaccac
    13561 gtcccccgcc tgggctttct cgatcaggga agcgagggaa tgcggcacgt cgaccgcgct
    13621 accggacagc gcatcgcgtg cctggcggac gagagcgttc gcgccgatga ccgtctcaag
    13681 gcatccccgt ccgccgcagc ggcagactgc cccgttcggg tcgaacacga gatggccgat
    13741 ctccccggcc attccacgtc cccggatggg cgtgttgctg atgaccagtc cggcgccgat
    13801 accggtggac cctttgatgt agaccacgat ctcggcatga ccgtctgtcg cgtacgtctg
    13861 ctcagccaac gcgcccaggt tggcgtcgtt gtcgagtgcg ccaggcacgc ccagccacgc
    13921 gcccaggtct cgcgacggat cgtcaccctc gctccatgga ggcagtatgg ggctggcgaa
    13981 tctgccggtc ctggggtcga ccatccgcgg cacggccacg ccgagggata ccacgtcctc
    14041 cagccccaga ctggttctgc cgacggcctc ccggatggct tgcttgagga ccggaatgac
    14101 ctcgctcatg cctctgttcg cgccgctcgc cacatgctcg ctgtgcgtct cggaaatggg
    14161 gcgatccaca cgtcgggcga ccactgtcgc ccggacgaag cccagatgga cgccgaccgc
    14221 gacgttgcgt gtgggaggca ggcgtactgt ccccctgcgt acggccctgg cctgttcggc
    14281 cttgtcgttg ggaaggactc cggccgtttg caactccccg acgatgttcg acacggtgga
    14341 ctgggcgagt ccggtgcgtc gggccaggtt ggcctgggta tctcccttga tcatgatcga
    14401 gatgagcaca tgcttgtggt tgatggctcg cgttcctcga gccggcccca gacggtcact
    14461 tagctgaagc atcgaccccc cgcaatatca ggtaattcag cgcttcatca tctcgacgtt
    14521 agcatggtga tcttcaattt gaacgtgggt cgccttcagg agggaaacgg gaagcatggc
    14581 cctgcatttc ttggggcgct tgagctattt gatgtctgag gaacgtccgc ggtgccgcgc
    14641 gctggggatt cgcggcacgt tggcccacaa gtttgttcgc acgacgaata ggcgaccgat
    14701 cttcaagtac aggctgattc gccagtggcc aggcagcggc gatgggggtg gccccacggc
    14761 cacgtcgttc aggtgacgtg gccgtggggg atcacatgat gccgagagtg atcagtggac
    14821 agttggcgtt gcgggtgtgg tggcggagtc cagcggcgat gttcggatgt tcggcgagtc
    14881 ggagagggtc gatgagcctg ctccgcggtc aggtcggtca cgccgcagac gcgttccagg
    14941 gcgaccttgc cggtggtgac gatccgctgg cggcgcacgg cctgcacagc gtgcgggaac
    15001 acgatcccgg tgacgtcggc ggccttgatc cagccgatct cgtcgcggcc gtgcgcggtg
    15061 atctcgttgg tctcgccgtc cacctcgcgc tgggcggtga ccaggccggt ccccgtcatc
    15121 gcggcgagca ggggacctgg gtgccatcgg tgcggcgagc accgtgcacg gtcttgccat
    15181 cgccatgcca cccgtggctg gcacttggag acccctcgcg ggttcggtgt gtcagggctg
    15241 ccggacgagg agaacgcggc gagagaacca tcactgattc gttcaccatc gtggccctcg
    15301 cgcgcgcacg gctgtctggc ctcctatgag acgtgccgcg cgccagccgc cgcgcctgcc
    15361 gcagaggcgg gagacggcgg gaaccgctgg gagtaggcgg tttctggcag ccgtcgctca
    15421 aacgctcaat gagtgctacc gaattgaacg aatcgatcgc tctggggaac tccagctcca
    15481 cgcagggccc cacgcacaga cgcggcgtgc acgacccaca agggccgtac gcgccgcgtc
    15541 tgtctcgtca aagtcagtgc ccggcccgcg cggacggcac ccgcgactcg gagatctcct
    15601 cgccaggctc catcggagcg gtgacgtcgt catcgtcccg ccgcttgccg atgtggttga
    15661 agaccaggtt gaggacgacc gcggcgacac agccggtgga gataccggag tccaggatga
    15721 tcatcgcggt gtccgggaag gcgtggtaga actccggcgc cgcgatcggg atcagcccga
    15781 cggccatcgc gaccgccacg atcagcacgt tgttgtcctt ctcaagcccc gccttggcca
    15841 gggtctggat accgctcgcc gcgaccgagc cgaacagcac gaccccggcg ccgccgagca
    15901 ccggccgggg cacggtggcg atcagtgagg cgacgaccgg catcaggccc atcaggatca
    15961 ggaagccacc ccccaccgcg accacgaacc ggctgcggat cttggtcatc gcgaccaggc
    16021 cgatgttctg ggcgaaggcg ctgcacatga aaccgttgaa gagcgggctg agcgcggagc
    16081 caaggcagtc ggcccgcagt ccggccgcga tcgtcttctc gtccgcgggc cgttcgacga
    16141 tctcaccgag cgccagcatg tcggcggtgg actcggtcat cgagacgatc atgacgacca
    16201 ccatcgacac gatggcggcc acggcgaact gcggggctcc gaagtggaat ggcgacggga
    16261 agccgacgac gctcgcctcg ccgaccgcgc tgaagtcggc gacgccgaac gggatcgcca
    16321 cgacagtccc gatcaccagg cccagcagta cggcgatctg cttgacgaac ccgctggtga
    16381 agcgacgtat cagcaggacg ataaccaggg tgatggcggc caggcccagg tacttcatgg
    16441 cgccgtagtc gtcgcccgcc ggatcgggcc cctgggccca gccgaaggcc acgggcatca
    16501 gcgagacgcc gatcagggtg atgacggtgc cggtgacgac cggcgggaag aagcgcacca
    16561 gcttggagaa gaacggggcg ccgatgaagc ccagcagccc cgcgacgatg atcgcgccga
    16621 agatgatcgg cagcgcgtcg tccgcgttcc cagcggactg ggtctggtcg acgatcgcga
    16681 gcatcggggc gacgcccgcg aaggtgacgc cgttgacgaa cggcagccgg gcaccgatgt
    16741 tccagacgcc cagggtctgc aggagggtgg ccagtccggc ggtgaagagg ctggccccgg
    16801 taaggaaggt gagctccttg ccggagagcc cgacggcggc tccgacgatc agcggcgggg
    16861 cgaccacacc cgcgtacatg gcggccacgt gctgcaggcc gctggtcatc atcttcagag
    16921 gcgggagctt ctcgtcgacc gggtgcgggg tgggcacctg gtcgtcggcc cgctcgtcct
    16981 cgggcacggc ggctgctttg cgaaccctgg gcgtttctgc cacggcggtt cctccggtcg
    17041 gttacacgtc gctggcgacg cgggtgtcag ggaggtcgta cgtacggaaa gtggtgcgcg
    17101 atgtggagtt gtggtcgtgc ggaggggtgc gacgtacgtc gccggtgctt gagggttctc
    17161 gggcacgcgc gttttggagc acgagcggtt tggggcgtga cggttcaccg ggccgagcgg
    17221 gtgcgggcca tggggccccc acccacccga ctcggctgcc gtgcaccccg ctcgggtcca
    17281 cggcgaccgg ccgggggccg tcccccccgg ccggactctg gggggatcag tcggctgcgg
    17341 cgatccgggc caggcgctgg gcctcatcgc gcgcgacgcg cgcgatggcg tcctcgtcgg
    17401 cggtcagcag gcggttgtgc tcgacgatct gctggccgtt gacgaacgag gcggtcaccg
    17461 gggcggccgc cccgaagacg agggcggtga ccgggtcggc gatcgaggag tgcccgatgc
    17521 cgtcgacctt ccacaggacg aagtcggcca gcttgcccgc ttcgatggag ccgatctgct
    17581 cggcgcggcc caggacctgg gcgccgccga aggtgccgag gcgcagggcc tggcgggcgt
    17641 tgagcgcggc ttcccggtgg gcaccgaggc ggttgatcag cagcgcgtta cgcagttcgg
    17701 tgtgcagttc gccggactcg ttggatgcgg tcccgtcgac gccgaggccg accgggacac
    17761 cggacttcag catgtccggg acgcgggcga taccggccgc gaggcgggcg ttggaggagg
    17821 ggcagtgggc gacaccggtc ttcgtacggg cgaaggcggc gatgtcggag tcgttcatat
    17881 gaacgcagtg cgccatccac acgtcctcgc cgagccagcc ggtcgactcg aagtagtcgg
    17941 tcggacccat gccgaagagt tcgtggcaga acttctcctc ctccacggtc tccgagccgt
    18001 gggtgtgcag ccgtacgccc ttggcgcggg ccagctcggc accctgcttc atcagctcgg
    18061 tggagacgga gaacggggag cagggggcga cggcgacctg cgtcatcgag tcgaaggagg
    18121 cgtcgtggtg ctggtcgacg gtctcggcgg tcgcggcgag cgcgccgtcg agggtctcca
    18181 cggcgaagtc cggcggcagt ccgccgtcct tctcgccgcg gtccatggaa ccgcgggcca
    18241 gggtgaagcg gacgcccatg tcccgggcgg cgccgatgat cgcgccggac aggtcgcctg
    18301 agcctcgcgg gtagacgtag tggtggtcca tcgcggtggt cacaccgccg cgggccatca
    18361 tggcgagcga gccctgggcg gcggccttcg ccatcgacgc gtcgatgcgc gcccacgtcg
    18421 ggtagagggc gacgagccag ttgaagaggt tgtgatcggt ggccaggccg cgggtgatcc
    18481 actggtagaa gtggtggtgc gtgttgacca ggcccggggt gagcaggtga ccggtgccgt
    18541 cgatgcggcg gaccacgttc tccaggtgcg ccggggccgt gccggcgccc accgcctcga
    18601 tccggttgtc cgctacgacg acgtagcccg acgcgtactc ggtgtcgtcc gcgtccacgg
    18661 tcgcgatggc acagttctcg ataacgatgc gcgaagccgc catggcggtc cctcgttcct
    18721 cttacgggtc ctcttacggg tggtgtcgca cccgggctcg tacggacgcg gctgcccccg
    18781 gtcgcctcct ggcccaccgg gacggccctg aggggggcct cccggtcggc caggggtcgg
    18841 tcagaggttg gtcaggtcga ccgggatctt cggctcgacg ccgtcacgca ggatcgtggc
    18901 ctcgatcagg ccgtacggac ggtccgccgc gtagtagacc tcgttgtcgt tcttcaggcc
    18961 gaacggctcc aggtccacca ggaagtgatg cttgttcggg agcgagaagc ggacctcgtc
    19021 gatctccgaa cggtggttga tgatgcgcga gcccatctgg tacagggtct gctgcagcga
    19081 gagcgagtag gtctcggcga aggcctgcag catgtgcttc ttaacctgct cgtaggactt
    19141 ctcccagttg ggcatgcgct gctcgtcgtc gctccagttg aagcgccagc ggccggacac
    19201 ctgggtggcc aggatgcggt cgtacgcttc cttgagcgtc gtgtaccggt ccttgatgta
    19261 gccccagaac tccgagttgg tggagttcat gacgacgagg tccttgaggc cggagacgac
    19321 ctcccacttc tcaccgtcgt aggtgatctg ggtgacgcgg gtctcctggc cctggcggac
    19381 gaacgagtgg ttgacctcgt ccgagccgat gaacttggag ttggcgtcgg cggtggcgat
    19441 gcggtcccag gcgtactcct cgatgcggat acgcgcccgg tggatcggct cctggctggt
    19501 cacgaagtga cgggccaggt ggatgccgaa ctgctcggcg gactcgatgc cgtactcctt
    19561 cgcgaacgcg tacaccgtgt tcttggtggt gtcggtcgga aggcagtggg cgttggaccc
    19621 cgagtagtgg acgtcgtcga ggtcgccgga gagcgcgacc gagacgttca ggtccttgat
    19681 gtggtgggtg tcgccgtccc gcgtgatctt gacgacgcgg ttctctgctt tgccgtactg
    19741 gttctggccg agaatcgtgg gcatgtctgc tagctccctc ggtaaacgga gtagccgaac
    19801 gggttgagca gcagcggtac gtgatagtgc tcgcccggct tgacggcgaa agtgatcgcc
    19861 acctccggga agaacgcacc gctgtccctt acgcgggggg cgtcctgctg cgcctcggct
    19921 tgctggttgg cgtggtgttg gggctggtgc gcgaagtacg cctcggtctc gaagtcgagg
    19981 cgtacgtggg tgatgccctc cggcagcgcc gggaggtcct tgcagcgccc gtccgcgtcg
    20041 gtcgcggaac cgccgagcgt gacccattcc tggtcgctgc cgctgcgggc ggcgagcgag
    20101 atggccacgg cctcggcggg gcggccgatg ctggtgtcca ggatgtgcgt ggacaccgaa
    20161 gcggtggtgt cggtgctcat cggttgcctt cttcctgctg ctctgcggac cgctgctcta
    20221 cgagccgggt cagccggatg cggttgatct tgccgagttc ggtgcggacg atggcccgct
    20281 cctgctcggc ggtgttctcg atccgggctt tgagagccgc gagcatctgc tcaccggtgg
    20341 cgccggtggc gcagatcagg aagacgtgac cgaacttgtc ctggtaggcc aggttgagtt
    20401 cgagcagctc ccgcttgagc tcttcggagg ctccggccat gccgcgctgt tcgcgcgacg
    20461 aggtcgggtc cccgggcttc gggcgcccga tcggcgggtg ccccgccatc gcttcttcca
    20521 gatccgccgt ggtcagctcg gccatggcgg cgtcgctggc ggcgaagagg gattcgacgg
    20581 tggcgtacgg gcgctgggcg agcagtttgc tcccccaggc cgaactggcg cacacctcgt
    20641 ggagctctgc ggcggccgca gtctcctcca aggcgttgaa ccgggtgaga cccggtgtgg
    20701 tacctgaagt cacgggttag cctccgtggc ttgttctgga cgggctggga ttagctaaga
    20761 ccttccggaa cacgacgtca acactttgtt gaaatcaatt gaacaaagga gccaccgccc
    20821 gacgactcgg gcgacgactc ctctacgttc cgtgacggcg ggcctgactg ccagcgctgg
    20881 cggtcctcac tacccgctcc tcgctactcg cccttcgccg cgttctcccg gttcaggtag
    20941 ttgtagacgg tgaagcggga cactccgagg gccccggcca ccgtctccac gccgtgccgt
    21001 acggagaagg cgccgcgccc ctcgagtatc cgtacgacct cctgcttcgc cttgcggtcc
    21061 agctcggaga gcggcctgcc gtgcttgcgc tccagggcgg ccaggatgcg gtccagggag
    21121 tccgcgagct ggggcagccg gaccgcgagg acgtcttcac cctcccaggc gaggacgacg
    21181 tcgtccccgt ccgcctcctg ggggctgagc agctcgccgc ccatggcgtc gacgagcggc
    21241 ttcacggccg tgacgaaggg gtggtcgcga ggctcggtca ccgcccctcc tcctctccga
    21301 cgacgttcac ctggagcgag acccgggtgg ccccggccgc cagggactta cgcagcaggg
    21361 cgtcgacggc ggtcagcacc gcgtcggcgc caccctcggc ggtgttgccg aaggggccga
    21421 cgtccacggc gtccagttcg gccgcctgga tgacgtcacg ggcgaccacc gcgtgggtgg
    21481 gcgcctcttc aaggtcgaag ggctcggtcg tgaactccac tctcaatcgc acgcggtcaa
    21541 cctactgcgc gttcgcagat ttgcggagtc ccacttgaca gccgaccggg accacaggca
    21601 atcttccatc aggtagaaac aactttccgc tatacggaag ggagcgccga ccctcatggg
    21661 attcacggac cagcgcttca acgtcaacct gtcgatcctc tacacggagc tcccgcttct
    21721 ggagcgtccc gcggccgccg ccgcggcggg cttcaccgcg gtggagctgt ggtggccctg
    21781 ggttgactcc cccaccccgg cgcagtccga gctcgacgcc ctgaagtcgg ctcttgagga
    21841 cgcgggcgtc cagttggtcg ggctcaactt ctacgctggc cagctgcccg gtcctgaccg
    21901 tggcgcgctg tccatccccg gcgaggagtc ggagaagttc cgcgcgaaca tcgacatcgc
    21961 cgcggacttc gccgcgtcgg tcggctgcaa ggcgctcaac gcgctctacg gcaaccgcgt
    22021 cgagggtgtg gacccggccg agcaggacgc gctcgcactg gagaacctcc agatcgcggc
    22081 ccgcgccgcc caccgcgtcg gcgcgatcct gctgatcgag gccctgaaca agcccgagtc
    22141 gccgctctgc ccgatcgtga gcgcccccaa ggccatcgag gtcgtggacg ccgtcaacgc
    22201 cgccacgggc ctgggcaacg ccaagttcct gatggacctt taccacctgt ccatgaacgg
    22261 cgagaacctc cccgaggtca tcgagaagta caccgccaag accgggcatg tgcagatcgc
    22321 cgacaacccg ggccgtggcg cgccgggcac cggagacctg ccgctcgagg accttctcga
    22381 ccagctgaag aaggccggtt acgacggctg ggtcggcctg gagtacaagg ccggcgacca
    22441 gtcgagcacc gagagcttcg gctggctccc ggccgaggcg cgcgccgcac gctgacggcc
    22501 cgcgctcgac ggccggacgc cagacgctgg acacggccac gcgctgactt acgcaccaca
    22561 gagtttctag gagacaccct catgagcaac aacctcccca agatcgcctg gatcggcctc
    22621 ggcatcatgg gctccccca
//
