LOCUS       NZ_WOFH01000013        21808 bp    DNA     linear   CON 29-SEP-2024
DEFINITION  Actinomadura litoris strain NEAU-AAG5 Scaffold13, whole genome
            shotgun sequence.
ACCESSION   NZ_WOFH01000013
VERSION     NZ_WOFH01000013.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinomadura litoris
  ORGANISM  Actinomadura litoris
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1  (bases 1 to 278344)
  AUTHORS   Cao,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-NOV-2019) Northeast Agricultural University, College
            of Life Science, No. 600 Changjiang Road, Harbin, Hei Longjiang
            150030, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 109x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009733595.1-RS_2024_09_29
            Annotation Date                   :: 09/29/2024 03:46:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,194
            CDSs (total)                      :: 8,115
            Genes (coding)                    :: 8,044
            CDSs (with protein)               :: 8,044
            Genes (RNA)                       :: 79
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 1 (5S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 14 of 71
            Pseudo Genes (incomplete)         :: 60 of 71
            Pseudo Genes (internal stop)      :: 4 of 71
            Pseudo Genes (multiple problems)  :: 6 of 71
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:00:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 146806
            Orig. end                         :: 168614
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            WOFH01000013.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21808
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /product="CDPS"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /rules="CDPS"
                     /tool="antismash"
     cand_cluster    1..21808
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /detection_rules="CDPS"
                     /kind="interleaved"
                     /product="terpene"
                     /product="CDPS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..21035
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11035](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11035)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            452..1111
                     /locus_tag="GNZ18_RS31665"
                     /old_locus_tag="GNZ18_31680"
     CDS             452..1111
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GNZ18_RS31665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GNZ18_31680"
                     /product="hypothetical protein"
                     /protein_id="WP_156220313.1"
                     /transl_table=11
                     /translation="MPPSRKATPIVGAVALVLVGGAVATGIALVMTYVRLYESPTLRDV
                     RISTGYYAFECLLVGVFTALGTLLARPRDPVTPVAAAVSGYVALYVGQRIGVIVYSVTQ
                     GYGMPSGHELNFILRPHFEGWDLLAVLAAGAIAGLRVVMVAGGTAPRGPAPAFGAQPGY
                     PHPQFQPPPPVRPPVPGHPPAYGPPGQPYQPPMGQFPPQGGAPGTPQGGGPPYGGV"
     protocluster    1032..21808
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[11031:11808](-)"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(11032..11808)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="2"
     gene            1174..1344
                     /locus_tag="GNZ18_RS40965"
     CDS             1174..1344
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019633626.1"
                     /locus_tag="GNZ18_RS40965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_173390944.1"
                     /transl_table=11
                     /translation="MGKTILTIIGVVLAIWVAMSVVGAIISMLKLFFFIGFVAVLVVLA
                     VTLVSKSKSRL"
     gene            1426..2979
                     /locus_tag="GNZ18_RS31670"
                     /old_locus_tag="GNZ18_31685"
     CDS             1426..2979
                     /EC_number="6.2.1.3"
                     /NRPS_PKS="Domain: AMP-binding (8-416). E-value: 1.5e-99.
                     Score: 325.3. Matches aSDomain:
                     nrpspksdomains_GNZ18_RS31670_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018654328.1"
                     /locus_tag="GNZ18_RS31670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_31685"
                     /product="long-chain-fatty-acid--CoA ligase"
                     /protein_id="WP_312874862.1"
                     /sec_met_domain="AMP-binding (E-value: 6.3e-109, bitscore:
                     358.3, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGLTDVLRERAELHPDRIAYIAGDLQSTYGDFDRRADRAAAALA
                     ASGVGHGDRVAILDKNSLEYAEQCFGAARIGAVQVPVNYRLEPDEVAYIVNNARAKVFI
                     VGPEFVPVLDAVASRLEHTTHLIVIGGPPGAYRDYSTWLDEAPAAVLPGTATSDVFVQL
                     YSSGTTGLPKGVMLTHDNFLSVLPLTHGAWDIDDASVMAIAMPMYHVAGHALSICVIYE
                     GITGVLNRDPDPTAIARAVERHRVTHLFLVPALLQFMPMIPAVAEADMSSLRIMLYGAS
                     PISEDVLRGAMAMLPHTGFIQVYGLTETTGAITMLPAADHDLSGPGLRRLRSAGLPNQG
                     CDLRIVDPSTLADLPAGAVGEILCRTPQNMKGYWRLPEATAATLLPGGWLRTGDAGYLD
                     EDGYLYIHDRVKDMIISGGENVYPAQIENVLMDHPAVGDCAVIGVPDERWGETPKAVVV
                     LAADATDEELIEHCRARLAHFKCPTSVERRDSIPRNPTGKILKRELRDPYWRDEDRPVR
                     "
     aSDomain        1450..2673
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GNZ18_RS31670_AMP-binding.1"
                     /evalue="1.50E-99"
                     /label="GNZ18_RS31670_AMP-binding.1"
                     /locus_tag="GNZ18_RS31670"
                     /protein_end="416"
                     /protein_start="8"
                     /score="325.3"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="RERAELHPDRIAYIAGDLQSTYGDFDRRADRAAAALAASGVGHGD
                     RVAILDKNSLEYAEQCFGAARIGAVQVPVNYRLEPDEVAYIVNNARAKVFIVGPEFVPV
                     LDAVASRLEHTTHLIVIGGPPGAYRDYSTWLDEAPAAVLPGTATSDVFVQLYSSGTTGL
                     PKGVMLTHDNFLSVLPLTHGAWDIDDASVMAIAMPMYHVAGHALSICVIYEGITGVLNR
                     DPDPTAIARAVERHRVTHLFLVPALLQFMPMIPAVAEADMSSLRIMLYGASPISEDVLR
                     GAMAMLPHTGFIQVYGLTETTGAITMLPAADHDLSGPGLRRLRSAGLPNQGCDLRIVDP
                     STLADLPAGAVGEILCRTPQNMKGYWRLPEATAATLLPGGWLRTGDAGYLDEDGYLYIH
                     DRVKDMIIS"
     misc_feature    1876..1878
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS_motif       1912..1962
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GNZ18_RS31670_0001"
                     /evalue="1.30E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="GNZ18_RS31670"
                     /protein_end="179"
                     /protein_start="162"
                     /score="20.9"
                     /tool="antismash"
                     /translation="LYSSGTTGLPKGVMLTH"
     CDS_motif       2488..2571
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GNZ18_RS31670_0002"
                     /evalue="2.90E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="GNZ18_RS31670"
                     /protein_end="382"
                     /protein_start="354"
                     /score="19.7"
                     /tool="antismash"
                     /translation="PAGAVGEILCRTPQNMKGYWRLPEATAA"
     gene            complement(2976..3584)
                     /locus_tag="GNZ18_RS31675"
                     /old_locus_tag="GNZ18_31690"
     CDS             complement(2976..3584)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF025343.5"
                     /locus_tag="GNZ18_RS31675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_31690"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_156220314.1"
                     /transl_table=11
                     /translation="MPKVVDHEGRRRAITAAACQVIAASGPAGATMRDIAAAAGCTTGM
                     VTHYFRGKDEVLLAALNSVSRAVADRVAALAADPSTGIETLLCECLPMDDRRRLEWRVW
                     IAFWGSAAHDPALAREQRDRYRTWREALQLVLATPGRPSGPPLEEAAETLMTAVDGIGI
                     QAVFDPRRWPPERQARQMRRQVAHVLADLDAAPDPGVVP"
     gene            3627..4136
                     /locus_tag="GNZ18_RS31680"
                     /old_locus_tag="GNZ18_31695"
     CDS             3627..4136
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF036613.5"
                     /locus_tag="GNZ18_RS31680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_31695"
                     /product="DUF5360 family protein"
                     /protein_id="WP_216651500.1"
                     /transl_table=11
                     /translation="MGKPAAPKSPAAGRTRGQAATGPGRVLKTLMLGTDVGFVLYWVIT
                     ALHVLPAESLFKDYENDLVVAWNWSFLPLDLLVSATGLTALALARRGVPAWRPLTVVSL
                     TLTSVSGLQAISYWTIRADVSLSWWLPNLFLLLYPLAPIAALLCGGTPRAAGSGSPRTA
                     GGGPRR"
     gene            complement(4081..4983)
                     /locus_tag="GNZ18_RS31685"
                     /old_locus_tag="GNZ18_31700"
     CDS             complement(4081..4983)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018654326.1"
                     /locus_tag="GNZ18_RS31685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_31700"
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="WP_312874863.1"
                     /transl_table=11
                     /translation="MRSPRALIPLLSVCGAAAVVAAAGAGAAIDGLPGGGPAHADGARE
                     TPAVTISAMTWNVCGVPRPGCPLGGRPEELTRRITTRMNATEVGGRTVKTNAVFLQDVC
                     SGQVKTLKRTGRFAKWTWAFAPFAGGPACAGGQGRPGVAVGVEAQMGGVRASRLPSPSY
                     AGRSAVCGDVPSWNTRVCGTQFSTKAEDPDGAWRRKQAHALVSVAGSGARVVVGGDLTD
                     GPEDPVLDPLYRAYAECDQSAAARTGAKTVQDWRGQALRKADYLFITKDTGTSSSVPDA
                     AVTSSDHRPLSAVIRFRQP"
     gene            complement(5140..6324)
                     /gene="tuf"
                     /locus_tag="GNZ18_RS31690"
                     /old_locus_tag="GNZ18_31705"
     CDS             complement(5140..6324)
                     /GO_function="GO:0003746 - translation elongation factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_process="GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="tuf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002607408.1"
                     /locus_tag="GNZ18_RS31690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_31705"
                     /product="elongation factor Tu"
                     /protein_id="WP_156220315.1"
                     /transl_table=11
                     /translation="MAKQAYERAKPHLNIGTMGHVDHGKTTLTAAITKVLAGRGLAAAV
                     PFEGIDRAPEERDRGITINVAHVEYATATRHYAHIDMPGHADFVKNMITGAAQVDGAIL
                     VVSAQDGAMPQTREHVVLAQQVGVRHVVVALNKSDMVEDAELLDLVELEVRELLSEYGF
                     PGEEVPVVRVSGLRALEGDPYWTSRIIDLLDAVDAYVPVPERVLDLPFLMPVENVLTIT
                     GRGTVVTGVVARGAVRLGDAVEVVGLGDSFTSVATGLETFGRSMDHAEAGDNTAMLLRG
                     VRRDQVRRGQVVSVPGAISPHTRFRARVRVLTAAEGGRSRPFFHGYRPQFHFRTTDVVG
                     GVDLGGEGGMAMPGDSVEMDVELGKPVAMTEGLGFAVREGGRTVGAGTVTALLD"
     gene            6761..7957
                     /locus_tag="GNZ18_RS31695"
                     /old_locus_tag="GNZ18_31710"
     CDS             6761..7957
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016915.5"
                     /locus_tag="GNZ18_RS31695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_31710"
                     /product="triacylglycerol lipase"
                     /protein_id="WP_156220316.1"
                     /transl_table=11
                     /translation="MSAWNAVAKLDPFKTRIDEEVSSPPPPDQEWRFADEGGTAWVFHA
                     EGRQHLARPVILSDGFHGGPTVLNDAIHNLEFAGYPFLSELRREGYDLIILGYQDCAAS
                     ILDNARAATACVKKAIAERRGEAKLAVGGFSMGGIITRYALAAMEHAEDDHQTGTYVSY
                     DSPHHGAWLPVAVQAFAHWVAEKFEGADGFSKLVDSPAARQLLEYHIAAFGEVPRVDPL
                     RREFLAKLTEVGSWPKGPRKIGVANGTGDGMPNGVPPGEKALITSPPDLITLYTQESGA
                     GRLVANVFGEEQRTDDLPMADGAPGGLLDFFRQLAQAVNDINLGISAEAVYPWTSFVPS
                     ISAMAAKTDKPWDNENLYGELANLASEFDDFKFADIDERHTDVTEDLCTWIIKELGEA"
     gene            complement(8025..8363)
                     /locus_tag="GNZ18_RS31700"
                     /old_locus_tag="GNZ18_31715"
     CDS             complement(8025..8363)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019631815.1"
                     /locus_tag="GNZ18_RS31700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_31715"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_156220317.1"
                     /transl_table=11
                     /translation="MGDEFHKDCPAREVLGHLAGRWTILVLTALLAQPRRYHELRAVVE
                     GISDKSLAATLRALQQDGLVHREVGAGQPPPVTYSVTPLGRGAAAALDPLLRWIRANAK
                     EITAHRRI"
     gene            8491..9255
                     /locus_tag="GNZ18_RS31705"
                     /old_locus_tag="GNZ18_31720"
     CDS             8491..9255
                     /NRPS_PKS="Domain: PKS_KR (3-179). E-value: 2.1e-09. Score:
                     29.5. Matches aSDomain:
                     nrpspksdomains_GNZ18_RS31705_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024950.5"
                     /locus_tag="GNZ18_RS31705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_31720"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_214615809.1"
                     /transl_table=11
                     /translation="MPSTTLVTGAARGLGASIARRLGTRGHHVIVNYRSSAADAAEVVR
                     GIEAAGGSASSAGADVTDPSAVDGLVTGILAARGRIDTVVVNANTAPPPFAALADLSWT
                     AFAAKVTGELAGAFHITKRVLAPMRAQGAGRIVYIGSTAADYVGGGRLAHGTAKSALAT
                     FARHVAAETARDGVSVLVVAPGAVRTPATAEILDGERGAVLARESVLGRVLEPEDVAEA
                     VAMAADPALHAATGTTLRVDGGWSVLVGGPSS"
     aSDomain        8500..9027
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GNZ18_RS31705_PKS_KR.1"
                     /evalue="2.10E-09"
                     /label="GNZ18_RS31705_PKS_KR.1"
                     /locus_tag="GNZ18_RS31705"
                     /protein_end="179"
                     /protein_start="3"
                     /score="29.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TTLVTGAARGLGASIARRLGTRGHHVIVNYRSSAADAAEVVRGIE
                     AAGGSASSAGADVTDPSAVDGLVTGILAARGRIDTVVVNANTAPPPFAALADLSWTAFA
                     AKVTGELAGAFHITKRVLAPMRAQGAGRIVYIGSTAADYVGGGRLAHGTAKSALATFAR
                     HVAAETARDGVSV"
     CDS_motif       8506..8571
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GNZ18_RS31705_0001"
                     /evalue="2.70E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="GNZ18_RS31705"
                     /protein_end="27"
                     /protein_start="5"
                     /score="16.8"
                     /tool="antismash"
                     /translation="LVTGAARGLGASIARRLGTRGH"
     CDS_motif       8878..9012
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GNZ18_RS31705_0002"
                     /evalue="1.90E+00"
                     /label="PKSI-KR_m1"
                     /locus_tag="GNZ18_RS31705"
                     /protein_end="174"
                     /protein_start="129"
                     /score="1.3"
                     /tool="antismash"
                     /translation="AQGAGRIVYIGSTAADYVGGGRLAHGTAKSALATFARHVAAETAR
                     "
     gene            complement(9285..10001)
                     /locus_tag="GNZ18_RS31710"
                     /old_locus_tag="GNZ18_31725"
     CDS             complement(9285..10001)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013353.5"
                     /locus_tag="GNZ18_RS31710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_31725"
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="WP_156220318.1"
                     /transl_table=11
                     /translation="MRLTVVLPGNAAPFQGMVHAECARWTRPDTELEVVVSGGPESVAS
                     RAEMARAAPALLDQVEAAGARGTDAVFIACAGDPAVEAAREVVDVPVAGGFEPALLTAL
                     SLGQRVGVLSVLPGVIPIFRELVRGHGLQDRCTSIRVIDAAVLHPDDQTAMVDLLDEQA
                     RAMAGGDEADVIVLGCVGFIRIARMLQDRLAARGAYLPVIDPTGAALLWLENCVRLGVR
                     PSRTTYAPPPEMAWKA"
     gene            complement(10001..11035)
                     /locus_tag="GNZ18_RS31715"
                     /old_locus_tag="GNZ18_31730"
     CDS             complement(10001..11035)
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012705.5"
                     /locus_tag="GNZ18_RS31715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_31730"
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_156220319.1"
                     /sec_met_domain="phytoene_synt (E-value: 3.1e-42, bitscore:
                     138.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 4.2e-33,
                     bitscore: 108.9, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSELDAAGLHDPRLRAAYAGCARFLRSRNSAAYPAARALLPPGH
                     RPYWDAILAFTTYVDDVLDDPDVAVAERTVRYERYIAQFHLLRTGEDPWPGEDGRPAHL
                     ARAFAHFSAAWRIPDDSVRLFLDTISTDLHVTQYETFAELAGYVHGVCAQGSQWGGLLF
                     HPRDEEAAAAAAEAMSFGLQLTDYLRDLREDLHDGRLYIPVEDLDRFGLTREGLERTVR
                     TGRTTPALRDLVEFQVRRAREYLDRAAGWWRLVHPSMRELPRQYVALARASTEQIVRDG
                     YDVLRPSRHRRAAAAFHAAVVLKAAGVRGRATRLLHPAPPPVRAPEPGAPARPRKASER
                     SGEF"
     gene            complement(11032..11808)
                     /locus_tag="GNZ18_RS31720"
                     /old_locus_tag="GNZ18_31735"
     CDS             complement(11032..11808)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017555804.1"
                     /locus_tag="GNZ18_RS31720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_31735"
                     /product="tRNA-dependent cyclodipeptide synthase"
                     /protein_id="WP_156220320.1"
                     /sec_met_domain="CDPS (E-value: 1.2e-73, bitscore: 241.5,
                     seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIKDETVARESDAGAGPGFVIEPFTPNCGAVYESRAHVVMGVSP
                     NNSYFNVARLTGLLGWLSATFARVDVVVPDSALVHTYLALGYVPERAAKKARGETAVLR
                     NRVLRAWKAAGGPGPGHAVHLMSTLAASPVYQRLLERVRRVLATDDRLHTACLKMSRQV
                     LAGRLGHAEPTPEQQELATDYLAAELPFFLDAAAIFDVPSSLCFYHRPVLLADLIFSGR
                     TPLRPSPRQGYALIYPTSPPGAAGSGRAAITNGEAR"
     misc_feature    complement(11395..11397)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(11873..11886)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.73"
                     /tool="antismash"
     misc_feature    complement(11886..11902)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.9"
                     /tool="antismash"
     misc_feature    11889..11902
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.89"
                     /tool="antismash"
     gene            complement(12040..12879)
                     /locus_tag="GNZ18_RS31725"
                     /old_locus_tag="GNZ18_31740"
     CDS             complement(12040..12879)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009086019.1"
                     /locus_tag="GNZ18_RS31725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_31740"
                     /product="NAD(P)H-binding protein"
                     /protein_id="WP_156220321.1"
                     /transl_table=11
                     /translation="MYLVIGATAHFGRQTVEALHAEGHGVRALTRTPEKAALPEGVEVV
                     QADLTVPRTLPAALDGVTAAFLVLQYGMDATALVEAAAEAGVRRIVFLSSGAVVDGADE
                     QPDVIAAYHAGVERLIAESGMEHTFLRLLFPAINSLTFGMQLQGGDVVRAPYTRASFSA
                     IHERDVADVAVRALVDEGHAGEVYDLTGPEALTQADQVAILAETLGRPLVAEDLDPEAT
                     RKQMARFMDGAFLDALFAMMAKAVDRPAEVNDVVRRIAGHPGRTYRQWTLDHAPDFS"
     misc_feature    12918..12931
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.13"
                     /tool="antismash"
     misc_feature    complement(12955..12970)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     gene            13095..13727
                     /locus_tag="GNZ18_RS31730"
                     /old_locus_tag="GNZ18_31745"
     CDS             13095..13727
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013053.5"
                     /locus_tag="GNZ18_RS31730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_31745"
                     /product="isochorismatase family protein"
                     /protein_id="WP_156220322.1"
                     /transl_table=11
                     /translation="MARTPLSPDNSAIVLVDHAIGFSNLIGSHTVEEVVSGTVALAKIA
                     KVFDMPLVVTNGLDEAPSGPLFPELAEVLGDHPVVRRREGFDAFLDEDFAAAIEATGRR
                     RLIMAGVQTDVCLALTALTALDRGHEVYAVVDASAATTRETHDTAVLRLVQAGVVPVNW
                     LAVGSELQRTWTDERTASGFAQVIFEHLGSWRHHHALTANAHEPAAG"
     gene            complement(13776..14960)
                     /locus_tag="GNZ18_RS31735"
                     /old_locus_tag="GNZ18_31750"
     CDS             complement(13776..14960)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.5"
                     /locus_tag="GNZ18_RS31735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_31750"
                     /product="MFS transporter"
                     /protein_id="WP_173390945.1"
                     /transl_table=11
                     /translation="MIGKPAGLPLHLTAATLLRVSAEGVATALVLTVQARTGDAATAGY
                     LQAAMTLPYVLSGPVIGNVVDRVARPRRVAVAMAVGYAAATALLLLLAGRSPLVLALCV
                     AAVIGCTEPVVVALTSLLPRFVPAERLSRAYGLEASSFNLAAIAGPGLAAALAGAMGGQ
                     YAGLAIVASGILGVLALPLLPFPGASGGAQKVSGVVMGGFTVLAEGRVLRALTTATTLA
                     WLGFGGVAVTAVLLAEHLGAEPSAGGRLLVAMAVGSLAGSLASSRWLRPRHAVPVMLAG
                     LVAFGTALATLAVVPSVPWAMAAFAVAGMVEGPVFAATLMLRQRESPPDRLGQVNTTAG
                     SLKIAASAVGAGLTAVSADAVGAVGLVLAIASFQFVGAGLGLLLLRFPRRPADG"
     gene            15003..16202
                     /locus_tag="GNZ18_RS31740"
                     /old_locus_tag="GNZ18_31755"
     CDS             15003..16202
                     /EC_number="3.5.3.6"
                     /GO_function="GO:0016990 - arginine deiminase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006527 - arginine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019633634.1"
                     /locus_tag="GNZ18_RS31740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_31755"
                     /product="arginine deiminase"
                     /protein_id="WP_214615802.1"
                     /transl_table=11
                     /translation="MTETTAHEHRVTSEVGRLRTVILHRPGAELKRLTPRNSDKLLFDA
                     IPWVGRAQEEHDAFAEALRSRDVEVLYITELLQDALEYEGAREQAITDVTADPRLGDQL
                     RRVLDGYLRDQDPERLAHTLIAGLAHEELKSGHGLAYRLMDRLDFIVDPLPGLLFTRDN
                     STWIGDRVAVTSLAMEARRRESALTGLIYAHHPRFAGVDPVYTADLEHLEGGDVLLLCP
                     GVIAVGTGERTTPAGVERLARQVIGAGLAHTVLAVPIAQERATMHLDTVCTMVDVDTVV
                     MYPPLAHSLTAYKVTLEGGDLRVSGPHPFLEAAAEAMSLDRLKVIDTGLDPVTAEREQW
                     DDGNNTLAVAPRLCVAYERNIETNAQLEASGIEVIRISGSELGTGRGGPRCMSCPVHRA
                     "
     gene            complement(16398..16865)
                     /locus_tag="GNZ18_RS31745"
                     /old_locus_tag="GNZ18_31760"
     CDS             complement(16398..16865)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024854.5"
                     /locus_tag="GNZ18_RS31745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_31760"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_216651501.1"
                     /transl_table=11
                     /translation="MSSGEGSVPEVSMTLGYLLKHAQHRMVELNTGALAPYGIDGRDLG
                     ILLTLAGHEPGSQQQAAKRLGIDRTTMVAMLDALERKGLVARRPHAEDRRRNVVELTEA
                     GRETLRLAVEASRAAEDELLAPLTPRAAGLLRDALRTIILRPEDGGDAGKP"
     misc_feature    complement(16897..16910)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.0"
                     /tool="antismash"
     misc_feature    16901..16916
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.28"
                     /tool="antismash"
     misc_feature    complement(16903..16916)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.93"
                     /tool="antismash"
     misc_feature    16904..16917
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 17.86"
                     /tool="antismash"
     gene            16938..17873
                     /locus_tag="GNZ18_RS31750"
                     /old_locus_tag="GNZ18_31765"
     CDS             16938..17873
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF027681.5"
                     /locus_tag="GNZ18_RS31750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_31765"
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_156220323.1"
                     /transl_table=11
                     /translation="MILVTGGMGFIGSHTVQALLDLGESCVLLQRRPAEHADERVTVEQ
                     GDITDLDALLGIGARHEITGIVHLAHSGPWPPDPDRPVEQARGALNGLLNVMRAAQDRG
                     VRRVGVASTIGVYSGITARGALREDMPLPMSAPHSIPTFKKIGELLNGHLADATGIEIV
                     NYRISGTWGPRDPHGALFFAAPELVHAAVQGREPDLSTLLAPAHAEDALDLCYVKDTGR
                     AIALLQLADHLNHRTYNVASGRATTNAEIIASIEQVIPGARVGLPTGGPAGRSHLDIGR
                     LHEDTGFKPEYDTARAVTDYIAWLRAGNEH"
     gene            complement(17877..19013)
                     /locus_tag="GNZ18_RS31755"
                     /old_locus_tag="GNZ18_31770"
     CDS             complement(17877..19013)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630404.1"
                     /locus_tag="GNZ18_RS31755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_31770"
                     /product="serine hydrolase"
                     /protein_id="WP_156220324.1"
                     /transl_table=11
                     /translation="MIKQRRALALALSAGVAAGGLTGTAAAADRTPLRELMHRLTTVDG
                     GPGAVLHVRDRRGGTVLTSGVADVTSRAPMRAGSEYRIGSMTKPFVATVLLQLVGERRV
                     VLDAPVERYLPGVVRGNGNDGRAVTVRQLLQHTSGIPDYLAHLDRQEILRNPLVHHDTR
                     GLVDFALTHPRTFEPGERWGYSNTNYLLAGMIIQRVTGHTYGREIRRRVIGPLGLRHTS
                     VPGDSTAIPGPHPRGYARPGPDAPLLDITAFNPSLAGASGSMISSGADLNRFLGALVGG
                     RLLRPAQLREMMRTRSTRNPGDPVDPHHRAYGLGLESKTLPCGGLYWGHSGDVLGFKTA
                     GGATVGGGQATVMVNLDPGATRAQGDDMTAAVRTALCR"
     misc_feature    complement(19007..19021)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.42"
                     /tool="antismash"
     gene            complement(19046..19672)
                     /locus_tag="GNZ18_RS31760"
                     /old_locus_tag="GNZ18_31775"
     CDS             complement(19046..19672)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GNZ18_RS31760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GNZ18_31775"
                     /product="hypothetical protein"
                     /protein_id="WP_156220325.1"
                     /transl_table=11
                     /translation="MSRIAFHLAPALMLAYGVVRLIDGRDGQHGPGPAWTVGHLLFFGS
                     LVLYGGVIAGLYGRIRATGGGTARRVATGVMTAVAGFGLVTFVRVTIVDLVVGVRAADA
                     AEKSTLADRYADVPAVLPQAVYEIGPVLFMLGLVALLVQYAVRAPGGRAVTALSPVLVV
                     LSFVTITLDLDLLPAGAALIWIALAICTRDRSSSAPAPAGAHAAV"
     gene            complement(19820..20473)
                     /locus_tag="GNZ18_RS31765"
                     /old_locus_tag="GNZ18_31780"
     CDS             complement(19820..20473)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017599463.1"
                     /locus_tag="GNZ18_RS31765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_31780"
                     /product="response regulator transcription factor"
                     /protein_id="WP_312874864.1"
                     /transl_table=11
                     /translation="MIRVVLADDQELVRSGFAMILDAQPDIEVAGEAGDGAAAIAAVRE
                     HAPDVALLDIRMPRLDGIEAAKAVCAQTPTRVIMLTTFDQDDYVYDALYAGASGFLLKD
                     VRRDDLVHAVRVVAAGESLLAPAVTRRLISDITRNRPRSGATASDRLAVLTERERETLS
                     LLGRGLSNAEIAAAMVVSEHTVKTHVSNVLAKLGIRDRVQAVIAAYETRLIEPS"
     gene            complement(20470..21588)
                     /locus_tag="GNZ18_RS31770"
                     /old_locus_tag="GNZ18_31785"
     CDS             complement(20470..21588)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020540985.1"
                     /locus_tag="GNZ18_RS31770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_31785"
                     /product="sensor histidine kinase"
                     /protein_id="WP_156220327.1"
                     /transl_table=11
                     /translation="MDVLIAAAVAVPVFVPFASAPEVTPLGVVLNLGTVVPLVWRRRAP
                     FAVAVVVACFAMGVSLHAQPGQNLQYGGLVAIYTLADLGRHRWQRWGFIGALVATIPPG
                     ALLVKDNDAAEFMFTLLLPVTAFLLGTLARTARERSDALVERSAQLEREREAEAARAAA
                     EERSRIARDMHDVLAHAVSIMVVQAEAGPVVVRSDPDQAERVFDAIADAGRDAMAQLRR
                     MLGVLKEEQDHGVRAPQPTIGELPGLVEHVDRTQVHVRLAVEGGSRAVPAEVDLAAYRI
                     VQEALTNTVKHADAREAEVRLRWTEHELEITVTDDGQGDAGADPGWRRGGSGLIGIRER
                     VAACGGTVEAGPLPGGGFRVSARLPHAAAVTA"
ORIGIN
        1 catagtcgtc cgcgccggtc tccagcccga cgaggcggtc ggtctcggtg ccgagcgcgg
       61 tgagcatcac gatcgggacg gccgaggtct cgcgcagcct ccggcacacc tccaggccgt
      121 ccatgccggg gagcatgagg tcgaggacga cgaggtcggg cgggcggtcg cgggccgtgc
      181 gcagcgccgt gttcccgtcc gcgacgcact cgacgtcgtg gccgtcgcgg gccaggtagc
      241 gcgcgacgac ctcggcgacc gtcgggtcgt cgtcgaccac gaggacacgc ccggcgtggg
      301 tcatcgggcc caccacggca gagagatcac cctttcacgc tacggcgccg cccaccgttt
      361 ccaccgatcg cgtcaccact ccgtaaggaa atcggtggcg ggaccctgcc atcccgtcgc
      421 caccgccgac gttcgtcgct ttaatgagcg aatgccgcca tctcgcaaag cgacccccat
      481 agtcggagca gtcgccctcg tcctggtcgg cggagcggtc gccaccggga tcgccctcgt
      541 catgacctat gtccgcctct acgagtcgcc gacgctgcgg gacgtgcgga tctcgaccgg
      601 ctactacgcg ttcgagtgcc tgctcgtggg cgtcttcacg gcgctcggga cgctgctcgc
      661 ccgcccccgc gacccggtca ccccggtcgc cgcggcggtc tccggctacg tcgccctgta
      721 cgtggggcag cggatcggcg tgatcgtcta ctcggtcacc cagggctacg ggatgccgag
      781 cgggcatgag ctgaacttca tcctcaggcc gcacttcgag ggctgggacc tgctggccgt
      841 gctcgcggcc ggggcgatcg ccgggctgcg cgtcgtgatg gtcgcgggcg gcacggcgcc
      901 gcgcgggccc gcgcccgcgt tcggcgccca gcccggatac ccgcacccgc agttccagcc
      961 gcccccgccg gtccggcctc ccgtgccagg ccaccctccg gcctacggac cgcctggaca
     1021 gccctaccag ccgcccatgg gacagttccc gcctcagggt ggcgcccccg ggacgcctca
     1081 gggtggtggt ccgccgtacg gcggggtcta gcacctttcg gctggtccca tagtgtgatg
     1141 ccgattcacg ttcgaacgaa tagcgtgtga cccatgggta agacaatcct gacgatcatc
     1201 ggcgtcgtac tcgcgatctg ggtcgcgatg agcgtggtcg gcgccatcat ctccatgctg
     1261 aagctgttct tcttcatcgg cttcgtggcc gtgctcgtcg tcctcgcggt gacgctcgtc
     1321 tccaagtcga agagccggtt gtagagcggc ccgccccctt gtcggggccc gccgttgccc
     1381 tcatgatgcc gggacaagca ggcggtcatc ggcgaaggga ccagcgtggc gggcctgacc
     1441 gacgtgctcc gcgaacgggc ggagctgcac cccgatcgca tcgcgtacat cgcgggcgac
     1501 ctacagagca cctacggtga cttcgaccgg cgggccgacc gggccgcggc ggcgctggcc
     1561 gcgtccggtg tcggccacgg cgaccgtgtc gcgatcctcg acaagaactc cctggagtac
     1621 gccgagcagt gtttcggcgc ggcgcggatc ggggccgtcc aggtaccggt gaactaccgg
     1681 ctggagccgg acgaggtcgc ctacatcgtc aacaacgcgc gggcgaaggt gttcatcgtc
     1741 ggccccgagt tcgtccccgt cctggacgcg gtggcgagcc ggcttgagca cacgacccac
     1801 ctcatcgtca tcggcggccc gcccggcgcc taccgcgact actccacctg gctggacgag
     1861 gcgcccgcgg cggtcttacc cgggaccgcc acctcggacg tgttcgtcca gctctactcc
     1921 tccggcacca cgggcctgcc caagggcgtg atgctgaccc acgacaactt cctctccgtg
     1981 ctcccgctga cccacggcgc gtgggacatc gacgacgcgt cggtgatggc gatcgcgatg
     2041 ccgatgtacc acgtcgccgg ccacgccctc agcatctgcg tgatctacga gggcatcacc
     2101 ggggtcctga accgcgaccc cgaccccacc gccatcgccc gggcggtcga gcgccaccgc
     2161 gtgacgcacc tcttcctcgt cccggccctg ctccagttca tgccgatgat cccggcggtc
     2221 gcggaggcgg acatgtccag cctgcggatc atgctgtacg gggcgtcgcc gatcagcgag
     2281 gacgtcctgc gcggcgccat ggcgatgctg ccccacaccg ggttcatcca ggtctacggg
     2341 ctgaccgaga ccaccggcgc gatcacgatg ctgcccgccg ccgaccacga cctgagcggt
     2401 cccgggctgc gccggctgcg cagcgccggg ctgcccaacc agggctgcga cctgcggatc
     2461 gtcgatccct cgacgctggc cgacctgccc gcgggcgcgg tcggcgagat cctgtgccgg
     2521 acgccgcaga acatgaaggg ctactggcgg ctgcccgagg cgaccgcggc cacgctgctg
     2581 cccggcggct ggctccgcac gggcgacgcc ggatacctcg acgaggacgg ctacctctac
     2641 atccacgacc gcgtcaagga catgatcatc tcgggcggcg agaacgtcta ccccgcccag
     2701 atcgagaacg tgctgatgga ccatccggcg gtcggcgact gcgcggtgat cggcgtcccg
     2761 gacgagcgct ggggcgagac cccgaaggcg gtcgtcgtgc tggcggcgga cgccaccgac
     2821 gaggagctca tcgagcactg ccgcgcgcgc ctggcccact tcaagtgccc gacgtcggtc
     2881 gagcgccgcg actcgatccc ccgcaacccc accggcaaga tcctcaagcg cgagctgcgc
     2941 gacccctact ggcgggacga ggaccggccc gtccgctagg gcacgacgcc cggatcggga
     3001 gccgcgtcca ggtcggccag gacgtgcgcc acctgccggc gcatctggcg cgcctgccgt
     3061 tcgggcggcc agcggcgggg atcgaacacg gcctggatgc cgatgccgtc caccgccgtc
     3121 atcagggtct cggcggcctc ctccagcggc ggcccggacg gacggccggg cgtcgccagg
     3181 acgagttgga gcgcctcccg ccacgtccgg tagcggtccc gctgttcccg cgccagcgcc
     3241 ggatcgtggg cggcggaccc ccagaacgcg atccacaccc gccattcgag gcggcggcgg
     3301 tcgtccatgg gcaggcactc gcacagcagc gtctcgatac cggtcgacgg gtcggcggcc
     3361 agcgcggcga cgcggtcggc cacggcccgg ctcaccgagt tcagggccgc cagcagcacc
     3421 tcgtccttgc cccggaagta gtgcgtgacc atgccggtgg tgcacccggc ggcggccgcg
     3481 atgtcgcgca tcgtggcccc ggccggtccg gacgcggcga tgacctggca ggccgcggcg
     3541 gtgatggcgc ggcggcgccc ctcgtgatcg acgaccttcg gcattgacac cggaggttac
     3601 atcatgcagg ttacgtaacc atggttatgg gaaaaccggc cgccccgaag agcccggcgg
     3661 cgggccggac gcggggccag gccgccacgg ggcccggacg cgtcctgaag acgctgatgc
     3721 tcggcacgga cgtcggcttc gtcctctact gggtgatcac ggccctgcac gtgctcccag
     3781 cggagtcgct gttcaaggac tacgagaacg acctcgtcgt ggcctggaac tggtcgttcc
     3841 tgcccctcga cctcctggtg agcgccaccg gcctgaccgc gctggcactg gcccgccggg
     3901 gcgtcccggc ctggcgcccg ctgacggtcg tctcgctcac gctgacgtcg gtgtcgggcc
     3961 tccaggcgat ttcctactgg acgatccgcg ccgacgtcag cctctcctgg tggctgccca
     4021 acctgttcct gctgctctat ccactggcgc cgatcgccgc cctgctgtgc ggcggaaccc
     4081 ctagggctgc cggaagcgga tcaccgcgga cagcgggcgg tggtccgagg aggtgacggc
     4141 cgcgtcgggc acgctggagg aggtgcccgt gtccttggtg atgaacaggt agtcggcctt
     4201 gcgcagggcc tgcccccgcc agtcctggac ggtcttcgcc ccggtacggg ccgccgcgct
     4261 ctggtcgcac tcggcgtagg cgcggtacag cgggtcgagc accggatcct cggggccgtc
     4321 ggtgaggtcg cccccgacga cgacgcgggc acccgaaccg gcgaccgaca ccagcgcgtg
     4381 cgcctgcttc cgccgccacg cgccgtccgg gtcctctgcc ttcgtgctga actgcgtgcc
     4441 gcagacccgg gtgttccagg acgggacgtc gccgcagacc gccgaccgtc cggcatagga
     4501 gggcgagggc agccgggacg cgcggacgcc gcccatctgc gcctcgacgc ccaccgcgac
     4561 accgggccgc ccctggccgc ccgcgcaggc gggccccccg gcgaacggcg cgaacgccca
     4621 ggtccacttg gcgaaccgcc cggtccgctt gagggtcttg acctgcccgg agcagacgtc
     4681 ctggaggaac acggcgttcg tcttgaccgt ccggccgccg acctcggtgg cgttcatccg
     4741 ggtggtgatc cgccgcgtca gctcctccgg ccgcccgccg agcgggcagc cgggacgcgg
     4801 caccccgcac acgttccagg tcatcgcgct gatcgtcacc gcgggggtct cgcgcgcccc
     4861 gtcggcgtgc gcgggcccgc cgcccggcag gccgtcgatg gcggcgccgg cacccgcggc
     4921 ggcgaccacg gcggcggctc cgcagaccga gaggagggga atcagggcgc ggggggatcg
     4981 cacacgttct ccagaaatgg gggtttcatc ggggatgatg tcgaaatccc accacatcaa
     5041 gatcgcatcc gccagcgatt cgccgccccc ggagcgtgag atttcccggt ccgagccgcg
     5101 cgcccggagg ctcgcgtccc ggaccgggag aaccggaccc taatccagga gggcggtgac
     5161 cgtcccggcg ccgaccgtgc gcccgccctc acggacggcg aagccgaggc cctcggtcat
     5221 cgcgaccggc ttgcccagct ccacgtccat ctcgaccgag tcgccgggca tcgccatgcc
     5281 gccctcgccg ccgaggtcca cgccgccgac gacgtcggtc gtgcggaagt ggaactgcgg
     5341 gcggtagccg tggaagaacg gcctgctccg cccgccctcc gccgccgtca gcacccggac
     5401 ccgcgcgcgg aaccgggtgt gcgggctgat cgcgcccggc acgctgacga cctggccccg
     5461 ccggacctgg tcgcgccgga cgccgcgcag cagcatcgcg gtgttgtcgc ccgcctccgc
     5521 gtggtccatc gaccggccga acgtctccag acccgtcgcc accgacgtga aggagtcgcc
     5581 gaggccgacg acctcgacgg cgtcgccgag ccggaccgcg ccccgcgcga cgacgccggt
     5641 gacgaccgtc ccgcgcccgg tgatcgtgag cacgttctcc accggcatga ggaacggcag
     5701 gtccagcacc cgctcgggca ccggcacgta ggcgtcgacc gcgtcgagca ggtcgatgat
     5761 ccgggacgtc cagtacgggt cgccctccag cgcccgcagc cccgacaccc gcacgaccgg
     5821 tacctcctcg cctgggaagc cgtactccga cagcagctcg cgcacctcca gctcgacgag
     5881 gtcgagcagc tcggcgtcct cgaccatgtc ggacttgttc agcgccacga ccacgtgccg
     5941 gacaccgacc tgctgcgcga gcacgacgtg ctcccgcgtc tgcggcatgg ccccgtcctg
     6001 cgcggacacg accaggatcg ccccgtccac ctgggccgcc ccggtgatca tgttcttcac
     6061 gaagtcggcg tgcccgggca tgtcgatgtg ggcgtagtgc ctggtcgcgg tcgcgtactc
     6121 gacgtgcgcg acgttgatcg tgatgccgcg gtcgcgctcc tccggcgccc ggtcgattcc
     6181 ctcgaacggg acggcggcgg cgagcccgcg tccggcgagc accttcgtga tcgccgcggt
     6241 cagcgtggtc ttgccgtggt cgacgtgccc catcgtgccg atgttcagat gcggcttggc
     6301 gcgctcgtaa gcctgcttgg ccatgatcct cgtcctcacc ctgtgttgcg tggaagtgag
     6361 aaccgcgcgg gcccctgaag ggctcgcaca tgtccaggcc acccccctcc gctggttctc
     6421 cggaggtggg acggagaggg gtcagcttcg cgcgccgcct gcgacggccg cgttcgccgc
     6481 ggctgccggg aaggcagccg gcaccgcgct cagcgggcag aggcccgcga gcgtcagggt
     6541 gccggccgcg aagtacatgc cgcgcacatt acgagccgcc cgttcggctg tcgacaggtt
     6601 tttccgggcg gcgatccccg aggtcgccgc cgggcggccc tgatcgccat caccttcgaa
     6661 gtgactgaag tgggacctgg gaggccagga gggacaggct catccgggcg actacttact
     6721 gttagcttga agacacgtta cgcaacgaac cggagggtca atgtccgcgt ggaacgccgt
     6781 cgcaaagctc gacccgttca agacccggat cgacgaggag gtgtcgtccc cgccgccgcc
     6841 ggaccaggaa tggcggttcg cggacgaggg cggaacggcc tgggtcttcc acgccgaggg
     6901 caggcagcac ctggccaggc ccgtcatcct gtcggacggc ttccacggcg gcccgaccgt
     6961 tctgaacgac gcgatccaca atctggagtt cgcgggttat ccgttcctct ccgaactgcg
     7021 gcgggagggc tatgacctga tcatcctcgg ttaccaggac tgcgccgcgt cgattctcga
     7081 caacgccagg gcggccacgg cctgcgtcaa gaaggcgatc gccgagcggc gaggagaggc
     7141 gaaactcgcc gtcggcggat tcagcatggg cgggatcatc acccggtacg cgctcgccgc
     7201 gatggagcac gccgaggacg accaccagac cggcacctac gtcagctacg acagcccgca
     7261 ccacggcgcg tggctcccgg tcgcggtgca ggcgttcgcg cactgggtgg ccgagaagtt
     7321 cgagggcgcc gacggcttct ccaagctggt cgacagcccg gccgcacggc agttgctgga
     7381 gtaccacatc gccgcgttcg gcgaggtccc gcgcgtcgat ccgctgcgcc gggagttcct
     7441 cgccaagctc accgaggtcg gctcgtggcc caagggcccg cggaagatcg gcgtggcgaa
     7501 cgggaccggc gacggcatgc ccaacggcgt gccgccgggc gagaaggcgc tgatcacctc
     7561 cccgccggac ctcatcacgc tctacacgca ggaatccggc gcgggaaggc tcgtcgccaa
     7621 cgtgttcggc gaggagcaga ggaccgacga cctgccgatg gccgacggcg cgcccggcgg
     7681 cctcctggac ttcttccggc agctcgccca ggccgtcaat gacatcaacc tgggcatctc
     7741 ggcggaggcc gtttatccgt ggacctcctt cgtcccctcc atcagcgcga tggcggcgaa
     7801 gaccgacaag ccgtgggaca acgagaacct ctacggcgaa ctcgccaacc tcgccagcga
     7861 gttcgacgac ttcaagttcg ccgatatcga cgagcgccac accgatgtga ccgaggacct
     7921 ctgcacctgg atcatcaagg aactcggcga ggcatgacga ccggcggggc ggccgacggg
     7981 ggccgatccc cccggcggcc gcgccccccg caaaaccggc ccggtcatat tcggcggtgc
     8041 gccgtgatct ctttcgcgtt ggcgcggatc catcgcagca gcgggtccag cgccgccgcc
     8101 gcgccgcggc cgagcggggt caccgagtac gtcaccggtg gcggctgccc cgcgccgacc
     8161 tcgcggtgca ccaggccgtc ctgctggagt gcgcgcaggg tggccgcgag gctcttgtcg
     8221 ctgatgccct cgaccaccgc gcgcagctcg tggtagcgac gcggttgggc gagcagcgcc
     8281 gtgaggacca ggatcgtcca gcggccggcg aggtggccca gcacctcgcg cgccgggcag
     8341 tccttgtgga actcgtcacc catcgcacct ctcccgggcc tccggtctgc gcgctcaccc
     8401 ccgggtgagg accacaccgc gtggtgagcg ccttcccccg cttctgcgct ctccttaggt
     8461 tagtgacctg ctcacgaccg aggaggaagc gtgccatcga ccacactcgt caccggtgcc
     8521 gcccgcggcc tgggcgcgtc catcgcacgg cggctcggga cgcgcgggca ccacgtgatc
     8581 gtcaactacc gctccagcgc cgccgacgcg gccgaggtcg tgcgcggcat cgaggccgcc
     8641 ggcggcagcg cgtcgagcgc cggggccgac gtcaccgacc cgtccgccgt cgacgggctg
     8701 gtgaccggga tcctcgccgc gcgcgggcgg atcgacacgg tcgtcgtcaa cgccaacacc
     8761 gctccgcccc cgttcgccgc cctggccgac ctgtcgtgga cggcgttcgc ggccaaggtc
     8821 accggcgagc tggccggcgc cttccacatc accaagcgcg tcctcgcgcc gatgcgggcg
     8881 cagggcgcgg gccggatcgt ctacatcggc agcaccgccg ccgactacgt cggcggggga
     8941 cggctcgcgc acggcacggc gaagtccgcg ctggccacct tcgcccgcca cgtcgccgcc
     9001 gagaccgcgc gcgacggcgt cagcgtgctc gtcgtggccc ccggcgcggt ccgcacaccg
     9061 gcgacggccg agatcctgga cggcgagcgc ggcgccgtcc tcgcccggga gtcggtgctc
     9121 ggccgggtgc tcgaacccga ggacgtcgcc gaggcggtgg cgatggccgc cgacccggcc
     9181 ctgcacgcgg ccaccggcac gaccctgcgg gtggacggcg gctggtcggt cctcgtcggc
     9241 ggcccgtcca gctgagcgcc cccgccggaa cgcccccgct cccctcacgc cttccatgcc
     9301 atctccggcg ggggcgcgta ggtggtgcgg ctgggccgca cgcccagccg cacgcagttc
     9361 tccagccaca gcagcgccgc gccggtcggg tcgatcaccg gcaggtaggc gccgcgtgcc
     9421 gcgagccggt cctggagcat gcgcgcgatc cggatgaacc ccacgcagcc gaggacgatc
     9481 acgtcggcct cgtcgccgcc ggccatcgcg cgggcctgct cgtccagcag atcgaccatg
     9541 gcggtctggt cgtcggggtg cagcaccgcc gcgtcgatga cgcggatcga ggtgcagcgg
     9601 tcctggaggc cgtggccgcg caccagctcc cggaagatgg ggatcacgcc gggcagcacg
     9661 ctcagcacgc cgacccgctg ccccagcgac agcgccgtga gcagcgccgg ctcgaacccg
     9721 ccggccaccg gaacgtcgac gacctcgcgc gcggcctcga cggccgggtc gccggcgcag
     9781 gcgatgaaga cggcgtcggt gccgcgcgcg ccggcggcct cgacctggtc cagcagcgcg
     9841 ggcgccgccc gcgccatctc ggcccgggac gccaccgact cggggccgcc gctgacgacg
     9901 acctccagct cggtgtcggg ccgggtccag cgggcgcact ccgcgtggac catgccctgg
     9961 aacggcgcgg cgttgccggg cagcaccacg gtcaggcgca tcagaactcc ccgctccgct
    10021 cgctcgcctt ccgggggcgc gcgggcgccc ccggttccgg cgcgcggacg ggcggcggcg
    10081 ccgggtggag cagccgggtc gcccgccccc ggacccccgc cgccttcagg accacggcgg
    10141 cgtggaacgc ggcggcggcg cggcggtgcc gggaggggcg caggacgtcg tagccgtcgc
    10201 ggacgatctg ctcggtcgac gcgcgcgcca gcgccacgta ctgccggggc agctcgcgca
    10261 tcgaggggtg caccaggcgc caccagccgg cggccctgtc caggtactcg cgcgcgcgcc
    10321 gcacctggaa ctcgaccagg tcccgcagcg ccggggtcgt ccggcccgtc cgcaccgtcc
    10381 gctccagccc ttcgcgggtc agcccgaacc ggtccaggtc ctccaccggg atgtagaggc
    10441 ggccgtcgtg caggtcctcg cgcagatcac gcaggtagtc ggtcagttgc aggccgaagc
    10501 tcatcgcctc cgccgccgcc gcggcggcct cctcgtcgcg cgggtggaac agcagaccgc
    10561 cccactgcga cccctgcgcg cacaccccgt ggacgtagcc ggccagctcg gcgaacgtct
    10621 cgtactgggt gacgtgcaga tcggtgctga tggtgtccag gaacagccgc acgctgtcgt
    10681 ccgggatccg ccaggccgcg ctgaagtgcg cgaacgcacg ggccaggtgg gcgggccgcc
    10741 cgtcctcgcc cggccagggg tcctcgcccg tgcgcagcag gtggaactgg gcgatgtagc
    10801 gctcgtaccg gacggtgcgc tccgcgaccg cgacgtcggg gtcgtcgagc acgtcgtcga
    10861 cgtaggtggt gaaggccagg atggcgtccc agtaggggcg gtggccgggc ggcagcagcg
    10921 cccgcgccgc cggataggcc gccgagttgc ggctccgcag gaaccgcgcg cagcccgcgt
    10981 aggccgcccg gagccggggg tcgtgcaggc cggcggcgtc cagctcgctc ttcatcgcgc
    11041 ttctccgttc gtgatcgcgg ccctgccgga accggcggcg cccggtggcg aggtggggta
    11101 gatcagcgcg tagccctgcc gggggctggg gcgcagcggc gtgcgaccgg agaagatcag
    11161 atccgccagc agcaccggac ggtggtagaa gcacagcgag gacggcacgt cgaagatcgc
    11221 cgccgcgtcc aggaagaacg gcagttcggc cgccaggtag tcggtcgcca gctcctgctg
    11281 ctcgggggtc ggctcggcgt gcccgagcct gccggccagc acctggcggc tcatcttcag
    11341 gcacgccgtg tgcagccggt cgtcggtggc gaggacccgc cgcacccgct ccagtaaccg
    11401 ctggtagacg gggctcgcgg ccagcgtcga catcaggtgc accgcgtggc ccggccccgg
    11461 gccgccggcc gccttccacg cgcgcagcac ccggttgcgc agcacggccg tctccccgcg
    11521 cgccttcttg gccgcgcgct cgggcacgta cccgagcgcc aggtacgtgt gcaccagcgc
    11581 gctgtcgggc accaccacgt ccacgcgggc gaaggtggcg ctcagccagc ccagcagccc
    11641 ggtcagccgc gccacgttga agtagctgtt gttcgggctg acgcccatga cgacatgcgc
    11701 cctgctctcg tagaccgcac cgcagttcgg ggtgaagggc tcgatgacga accctggtcc
    11761 ggctccggcg tccgactcgc gtgccacagt ttcgtctttg atggccatgg cctctcgtgt
    11821 ggtccccggc gcgcccgtca tggtcccccg acgtcgcacc ccgattccgt accaataatc
    11881 actacatgta gcaatatgat cacttccagc gacataagca gatgctggcc acacaggcat
    11941 ccctgtatcc cggcggagcc ggggaaggaa aaccagcgcc gaccgctaca accaccaggt
    12001 caaaccccag cccccggcgc gggggccggg gggcggggtt caggagaagt cgggcgcgtg
    12061 gtcgagggtc cactgccggt aggtgcggcc cgggtgcccg gcgatgcgcc gcacgacgtc
    12121 gttgacctcc gcgggccggt cgacggcctt ggccatcatg gcgaagaggg cgtcgaggaa
    12181 cgcgccgtcc atgaaccggg ccatctgctt cctggtcgcc tcggggtcga ggtcctccgc
    12241 gacgagcggg cgcccgagcg tctcggcgag gatcgcgacc tggtcggcct gcgtgagcgc
    12301 ctcgggcccg gtcaggtcgt agacctcccc cgcgtggccc tcgtcgacca gggcgcggac
    12361 ggcgacgtcc gcgacgtcgc gctcgtggat cgcgctgaag gaggcccggg tgtagggggc
    12421 ccggacgacg tcgccgccct gcaactgcat gccgaaggtg agcgagttga tggcggggaa
    12481 cagcagccgc aggaacgtgt gctccatgcc ggactcggcg atgagccgct cgacgcccgc
    12541 gtggtaggcg gcgatgacgt cgggctgctc gtccgcgccg tcgacgacgg cgcccgagga
    12601 caggaacacg atccgccgca caccggcctc ggcggccgcc tcgaccaggg cggtcgcgtc
    12661 catgccgtat tgcaggacga ggaaggcggc cgtcacgccg tcgagcgcgg cggggagcgt
    12721 ccgggggacg gtcaggtcgg cctggacgac ctcgacaccc tcgggcagcg cggccttctc
    12781 gggggtgcgg gtgagcgcgc ggaccccgtg gccctccgcg tgcagggcct cgacggtctg
    12841 gcggccgaag tgggcggtgg cgccgatgac gagatacatg ggggtggctc cttcggtaac
    12901 cgctggtgag gacgcgttca aactatcaga acggaatact tcgttccaaa tcgacgtgag
    12961 cggcgtcaca ggctccgggg cggccgggac gaaatatttg cctgcgcaga cagttttact
    13021 catcgccggc ttcggccggc acggggtcgg atccgcccgc acccgtcagt tccgacgtca
    13081 gaagaggtaa ggcaatggct cgcacaccgc tctccccgga caacagcgcg atcgtcctcg
    13141 tcgaccacgc gatcgggttc tccaacctga tcgggtccca cacggtcgag gaggtcgtca
    13201 gcggcacggt cgcgctggcg aagatcgcca aggtcttcga catgccgctg gtcgtcacca
    13261 acggcctcga cgaggcgccg tccggcccgc tgttcccgga gctcgccgag gtcctgggcg
    13321 accacccggt cgtccgccgc cgcgaggggt tcgacgcgtt cctggacgag gacttcgccg
    13381 ccgcgatcga ggcgaccggg cgcaggcggc tgatcatggc gggcgtccag accgacgtct
    13441 gcctggccct gaccgccctg accgcgctcg accgcggcca cgaggtgtac gcggtggtgg
    13501 acgcctcggc cgccaccacc agggagaccc acgacaccgc cgtgctgcgg ctggtccagg
    13561 ccggggtggt cccggtgaac tggctggccg tcggatccga actccagcgc acctggacgg
    13621 acgagaggac cgcgtccggc ttcgcccagg tgatcttcga gcacctcgga tcgtggcggc
    13681 accaccacgc gctcacggcg aacgcccacg agcccgcggc cgggtagcac gacgcgcggc
    13741 ggccggcggg caccccgccg gccgccaccg cccgttcagc cgtccgcggg tcttctgggg
    13801 aagcgcagga ggagcaggcc gagaccggcg cccacgaact ggaaggacgc gatggccagg
    13861 acgaggccga ccgcgcccac cgcgtccgcc gagacggcgg tcaggcccgc gcccaccgcc
    13921 gatgcggcga tcttgaggct gcccgcggtg gtgttgacct ggccgaggcg gtccgggggc
    13981 gactcgcgct ggcgcagcat cagcgtcgcc gcgaacaccg ggccctcgac catccccgcc
    14041 accgcgaacg ccgccatcgc ccacgggacg gacggcacca cggccagcgt cgccagcgcc
    14101 gtcccgaacg cgaccagccc ggccagcatg acgggcacgg cgtgccgggg ccgcagccac
    14161 cggctggagg ccagcgaccc cgcgagcgac ccgaccgcca tcgccaccag cagccgtccg
    14221 cccgcgctgg gctccgcgcc gaggtgctcg gcgagcagca ccgccgtcac cgcgaccccg
    14281 ccgaacccga gccaggccag cgtggtcgcg gtcgtcagcg cccgcagcac ccgtccctcg
    14341 gccaggacgg tgaacccgcc catcacgacc ccggacacct tctgcgcgcc ccccgacgcc
    14401 ccggggaagg gcagcagcgg cagggccagc acgccgagga tcccgctcgc cacgatcgcg
    14461 agcccggcgt actggccccc catcgccccg gcgagcgccg ccgcgagccc ggggcccgcg
    14521 atcgcggcga ggttgaaact ggacgcctcc agcccgtacg cgcgggagag ccgctcggcg
    14581 ggcacgaaac gcggcagcag gctggtcagc gccaccacca ccggctcggt gcagccgatc
    14641 accgccgcga cgcacaacgc cagcaccagc ggcgagcgtc ccgccaggag cagcagcaac
    14701 gccgtcgcgg ccgcgtatcc caccgccatc gcgaccgcga cacgccgggg acgcgccacc
    14761 cggtcgacca cgtttccgat caccgggccg ctcagcacgt acggcagcgt catcgccgcc
    14821 tggaggtaac cggcggtcgc ggcgtccccc gtgcgggcct ggacggtgag caccagcgcc
    14881 gtcgccacac cctccgcgga aacacgcagc aacgtcgcgg ccgtcaggtg cagagggagc
    14941 ccggcgggct tgccgatcac cccgagatcg tgccacagga ccggcgacct agactttcac
    15001 atgtgacgga gacgactgcg cacgaacaca gggtcaccag cgaggtcggg cggctgcgga
    15061 ccgtcatcct ccatcgcccg ggtgcggagc tgaaacggct cacgccccgc aacagcgaca
    15121 agctgctgtt cgacgccatc ccctgggtcg gccgcgccca ggaggagcac gacgcgttcg
    15181 ccgaggccct ccggagccgc gacgtcgagg tcctctacat caccgagctc ctccaggacg
    15241 ccctcgaata cgagggcgcc cgcgaacagg ccatcaccga cgtcaccgcc gacccgcgcc
    15301 tcggcgacca gctccgccgc gtcctggacg gctacctgcg cgaccaggac cccgagcgcc
    15361 tcgcccacac cctgatcgcc gggctcgccc acgaggagct gaagtcgggc cacggcctgg
    15421 cctaccgcct catggaccgc ctggacttca tcgtcgaccc cctccccggc ctgctgttca
    15481 cccgcgacaa cagcacctgg atcggcgacc gcgtcgccgt gaccagcctc gccatggagg
    15541 cccgccgccg cgagtccgcc ctgaccggcc tcatctacgc ccaccacccc cgcttcgcgg
    15601 gcgtcgaccc cgtctacacc gccgacctcg aacacctcga aggcggcgac gtcctgctcc
    15661 tgtgccccgg cgtgatcgcc gtcggcaccg gcgagcgcac caccccggcg ggcgtcgagc
    15721 ggctcgcccg ccaggtgatc ggcgcgggcc tcgcccacac cgtcctggcc gtccccatcg
    15781 cgcaggaacg tgccacgatg cacctcgaca ccgtctgcac gatggtggac gtcgacaccg
    15841 tcgtcatgta cccgccgctc gcccactccc tgaccgccta caaggtcacc ctggagggcg
    15901 gcgacctccg cgtctccggc ccccacccct tcctggaggc cgccgccgaa gcgatgtcgc
    15961 tggaccgcct caaggtcatc gacaccggcc tcgaccccgt caccgccgaa cgcgagcagt
    16021 gggacgacgg caacaacacc ctcgccgtcg ccccccgcct ctgcgtcgcc tacgaacgca
    16081 acatcgagac caacgcccaa ctcgaagcgt ccggcatcga ggtcatccgc atcagcggca
    16141 gcgaactggg cacgggccgc ggcggccccc gctgcatgtc atgtccggtt catcgggcgt
    16201 agcccccggc gccggccgcc ggcgccccct ccttcaacgg gccacgcgag cgaccgctgc
    16261 atcgctccga acccgcctgg cgactcgctt cgctcgaatc cgccttcgga ggcgatagcg
    16321 gcgcccgggg ccgtcgcccg tcgccgacct tccggccggg caggccctgg cccggaggcg
    16381 ttctgaggtg tagcgggcta cggcttcccg gcgtcgccgc cgtcctccgg gcggaggatg
    16441 atcgtccgga gggcgtcccg tagcagcccg gcggcccgcg gggtgagcgg cgcgaggagt
    16501 tcgtcctcgg cggcccggct ggcctcgacg gccagccgca gggtctcccg cccggcctcg
    16561 gtcagctcga ccacgttgcg ccgccggtcc tcggcgtgcg gacggcgcgc cacgagcccc
    16621 ttgcgctcca gcgcgtccag catcgcgacc atcgtcgtcc ggtcgatccc gagccgcttc
    16681 gccgcctgct gctgggaccc cggctcgtgc ccggcgagcg tgagcaggat tccgagatcc
    16741 cgcccgtcga tgccgtaggg cgccagcgcg cccgtgttca gctcgaccat ccggtgctgc
    16801 gcgtgcttga gcagataccc gagggtcatg ctcacctcgg gcaccgaacc ctcaccgctg
    16861 gacacccgtc gactctatcg ctagcctgat cgtcagtagt actgataatc agtagaacga
    16921 cagaagatgg agacgcaatg atcctcgtca ccggaggcat gggattcatc ggttcgcaca
    16981 ccgtgcaagc gctgctcgac ctgggtgaga gctgtgtgct gctccagcgc cgtccggcgg
    17041 agcacgccga cgagcgggtg accgtcgagc agggcgacat caccgatctg gacgcgttgc
    17101 tcggcatcgg cgcccgccac gagatcaccg gcatcgtgca cctcgcgcac tccggcccct
    17161 ggccgccgga ccccgaccgc cccgtcgagc aggcgcgcgg cgccctgaac ggcctgctca
    17221 acgtcatgcg ggccgcccag gaccggggcg tccgccgggt cggcgtcgcg agcacgatcg
    17281 gcgtctactc cggcatcacc gcccggggcg cgctcaggga ggacatgccg ctcccgatgt
    17341 ccgcccccca ctcgatcccg accttcaaga agatcggcga actgctcaac gggcacctgg
    17401 cggacgccac cggcatcgag atcgtcaact accgcatctc cggcacctgg ggcccgcgcg
    17461 acccccacgg cgccctgttc ttcgcggcgc ccgagctggt gcacgcggcc gtccagggaa
    17521 gggaaccgga cctctccacc ctgctcgcgc ccgctcacgc ggaggacgcc ctcgacctct
    17581 gctacgtgaa ggacacgggc cgcgccatcg ccctcctcca actggccgac cacctgaacc
    17641 accgcaccta caacgtggcc tccggccgcg cgacgaccaa cgccgagatc atcgcgtcca
    17701 tcgagcaggt gatcccaggc gcccgggtcg gcctccccac cggaggtccc gccggccgga
    17761 gccacctgga catcggccgg ctccacgagg acaccggctt caagcccgaa tacgacaccg
    17821 cccgcgccgt caccgactac atcgcctggc tccgagcagg gaacgagcat tgagcgctac
    17881 cggcagagcg ccgtccgcac ggcggccgtc atgtcgtcgc cctgcgcgcg cgtggcgccc
    17941 gggtcgaggt tcaccatgac ggtcgcctgg ccgccgccga ccgtggcgcc gcccgcggtc
    18001 ttgaatccga ggacgtcacc gctgtgcccc cagtacaggc cgccgcaggg cagcgtcttg
    18061 ctctccaggc cgaggccgta ggcccggtgg tgggggtcga cggggtcgcc ggggttgcgg
    18121 gtcgagcggg tcctcatcat ctcccgtagc tgggccgggc ggagcagcct gccgccgacg
    18181 agggcgccga ggaaccggtt gagatcggct ccggaagaga tcatcgagcc cgaggcgccc
    18241 gccagcgagg ggttgaacgc ggtgatgtcc aggagcggcg cgtcggggcc cggtcgcgcg
    18301 tatccgcgcg ggtgcggtcc ggggatcgcc gtgctgtcac cgggcacgga ggtgtggcgc
    18361 agcccgagcg gtccgatgac gcggcggcgg atctcccggc cgtaggtgtg gccggtgacc
    18421 ctttggatga tcatgccggc cagcaggtag ttggtgttgg agtagcccca gcgttcgccg
    18481 ggctcgaacg tgcgcggatg ggtgagcgcg aagtcgacca ggccgcgggt gtcgtggtgg
    18541 accagcgggt tcctcaggat ctcctgccgg tcgaggtggg cgaggtagtc ggggatgccg
    18601 ctggtgtgct ggagcagttg gcggacggtg acggcgcgcc cgtcgttgcc gtttccgcgt
    18661 acgacgccgg gcaggtagcg ctcgaccggc gcgtccagga cgacgcggcg ctctcccacc
    18721 agttggagca ggaccgtggc cacgaacggc ttggtcatgc tgccgatccg gtactcgctg
    18781 ccggcgcgca tcggcgcgcg gctcgtgacg tccgcgacgc cgctggtcag cacggtgccg
    18841 ccgcgccggt cccggacgtg caggaccgct ccgggcccgc cgtcgaccgt ggtcagccgg
    18901 tgcatgagtt cccgcaacgg agtccggtcg gcggcggcgg cggtgccggt cagcccgccc
    18961 gccgcgacac cggccgacag ggccagggcg agcgcacgcc tctgcttgat catgagtgtc
    19021 tcccgtgaaa ttcgaaggtt cgcggctaga ccgcggcgtg ggccccggca ggtgcggggg
    19081 cggacgaact ccggtcgcgg gtgcagatcg cgagggcgat ccagatcagc gccgcgcccg
    19141 ccgggagcag gtccaggtcg agcgtgatgg tgacgaagct gagaacgacc aggacggggc
    19201 tcagggcggt caccgccctg ccgcccgggg cgcggaccgc gtactggacg agcagcgcca
    19261 ccagcccgag catgaagagc accgggccga tctcgtagac cgcctggggg agcacggcgg
    19321 ggacgtcggc gtaccggtcg gcgagcgtgc tcttctcggc ggcgtccgcg gcccggacgc
    19381 cgacgacgag gtcgacgatc gtgacgcgga cgaacgtcac cagcccgaag ccggcgaccg
    19441 cggtcatgac gcccgtcgcg acgcggcgcg cggtaccgcc gccggtggcc ctgatgcggc
    19501 cgtacaggcc cgcgatcacc ccgccgtaca gcacgaggga accgaagaag agcagatggc
    19561 ccaccgtcca tgcgggtcct gggccgtgct gcccgtcacg gccgtcgatc agccggacga
    19621 cgccgtaggc gagcatgaga gcgggggcga ggtgaaaggc gatcctggac atgagcggtt
    19681 ctcccgaggt tcgagccgtg cgttcctgcg tctcgatcct cgggcgaacc ggtgtgcggg
    19741 cggatcgccg ccgcggcggg tcttggggca tcggtggcgc gggggaggac gggggcgagg
    19801 ctcccccgcg cgacggaggt caggagggtt cgatcaggcg cgtctcgtac gcggcgatca
    19861 cggcctggac gcggtcgcgg atgccgagct tggcgaggac gttgctcacg tgggtcttca
    19921 cggtgtgctc actgacgacc atggccgcgg cgatctccgc gttcgacagc ccgcggccga
    19981 gcagggacag ggtctcgcgc tcgcgttcgg tgaggaccgc caggcggtcg gaggcggtcg
    20041 cgccggagcg cggccggttg cgggtgatgt cggagatcag gcggcgggtg acggcgggag
    20101 ccagcagcga ctcccccgcc gcgaccacgc ggaccgcgtg cacgaggtcg tcgcggcgca
    20161 cgtccttgag caggaagccg ctggcccccg cgtagagcgc gtcgtagacg tagtcgtcct
    20221 ggtcgaacgt ggtcagcatg atcacgcggg tcggggtctg cgcgcacacg gccttcgcgg
    20281 cctcgatgcc gtccagcctc ggcatgcgga tgtcgagcag cgcgacgtcg ggggcgtgtt
    20341 cgcggaccgc ggcgatcgcg gcggcgccgt cgcccgcctc gcccgccacc tcgatgtcgg
    20401 gctgcgcgtc caggatcatg gcgaagccgc tgcggaccag ctcctggtcg tcggcgagca
    20461 cgaccctgat cacgcggtca ccgccgcggc gtggggaagc cgcgccgaga cgcggaaccc
    20521 gccgcccggc aggggaccgg cctcgacggt gccgccgcag gcggcgacgc gctcacggat
    20581 gccgatgaga ccgctgcccc cgcgccgcca tcccgggtcg gcccccgcgt cgccctgccc
    20641 gtcgtcggtc accgtgatct ccagttcgtg ctcggtccag cggagccgga cctcggcctc
    20701 ccgcgcgtcg gcgtgcttca ccgtattggt gagcgcctcc tgcacgatgc ggtaggccgc
    20761 caggtcgacc tcggcgggga ccgcccggct cccgccctcg accgcgagcc gcacgtggac
    20821 ctgggtgcgg tcgacatgct cgaccaggcc gggaagctcg ccgatcgtgg gctggggcgc
    20881 gcggacgccg tggtcctgct cctccttgag gacgcccagc atccggcgca gttgggccat
    20941 cgcgtcccgg cccgcgtcgg cgatggcgtc gaagacccgt tcggcctggt cgggatcgga
    21001 gcggaccacc accggaccgg cctcggcctg caccaccatg atgctgacgg cgtgcgcgag
    21061 cacgtcgtgc atgtcgcggg cgatgcgcga gcgctcctcc gccgccgccc gcgccgcctc
    21121 ggcctcccgc tcgcgttcga gctgcgcgga ccgctccacc agcgcgtccg accgttcccg
    21181 tgcggtccgt gcgagcgtcc ccagcaggaa cgccgtcacg ggcaggagca gcgtgaacat
    21241 gaactcggcc gcgtcgttgt ccttgaccag cagcgcgccg ggcgggatcg tcgccacgag
    21301 cgcgccgatg aagccccagc gctgccagcg gtgccgcccc aggtcggcga gcgtgtagat
    21361 ggccaccagc ccgccgtatt gcaggttctg gcccggttgg gcgtgcagcg agacccccat
    21421 ggcgaagcag gccacgacca ccgcgaccgc gaagggagcc cgccgccgcc acaccagggg
    21481 cacgaccgtc ccgaggttga gcaccacccc gagcggcgtc acctccggcg ccgaggcgaa
    21541 cggcacgaac accggcaccg cgaccgccgc ggcgatcagc acatccaccc gcccagcgcc
    21601 cgcaccggaa cgcagcggaa gaccaaacct acggaaccga cccgtcatcc acccagtatc
    21661 gccaccccag acggaatgcc cgcctcgccc gcacgaggga tatcacgcca ctgaccacct
    21721 gaaaccgccg gttccagcgc gacaacgtgc gaaggcgggg ggggttgaag tagtaagccc
    21781 agcccgcagc gaccgggacg ttgcgatc
//
