LOCUS       NZ_WOFH01000002        22575 bp    DNA     linear   CON 29-SEP-2024
DEFINITION  Actinomadura litoris strain NEAU-AAG5 Scaffold2, whole genome
            shotgun sequence.
ACCESSION   NZ_WOFH01000002
VERSION     NZ_WOFH01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinomadura litoris
  ORGANISM  Actinomadura litoris
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1  (bases 1 to 842719)
  AUTHORS   Cao,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-NOV-2019) Northeast Agricultural University, College
            of Life Science, No. 600 Changjiang Road, Harbin, Hei Longjiang
            150030, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 109x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009733595.1-RS_2024_09_29
            Annotation Date                   :: 09/29/2024 03:46:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,194
            CDSs (total)                      :: 8,115
            Genes (coding)                    :: 8,044
            CDSs (with protein)               :: 8,044
            Genes (RNA)                       :: 79
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 1 (5S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 14 of 71
            Pseudo Genes (incomplete)         :: 60 of 71
            Pseudo Genes (internal stop)      :: 4 of 71
            Pseudo Genes (multiple problems)  :: 6 of 71
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:00:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 820144
            Orig. end                         :: 842719
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            WOFH01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22575
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene"
                     /region_number="5"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22575
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22575
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[10000:13754]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13754
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(32..970)
                     /locus_tag="GNZ18_RS08045"
                     /old_locus_tag="GNZ18_08045"
     CDS             complement(32..970)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) SubclassB1"
                     /gene_kind="resistance"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012892744.1"
                     /locus_tag="GNZ18_RS08045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_08045"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_156215528.1"
                     /transl_table=11
                     /translation="MSDAPDLDGPGDPRLVEVSDGIFAYLQPDGTWWINNTGFLVGARG
                     VTSVDACSTERRTRAYLEAIGSVTPRPVRTLVNTHHHGDHTFGNYLFSGATVVGHEGTR
                     QGALDWGMPFDEPFWTKVEWGGVELEPPFLTYADGVTLWVDDLRCEVRHVGTPAHTTND
                     SIVWIPERRVLFCGDLLFNGGTPFLMQGSVDGAIRVLTEVIAPLEAETIVPGHGPVAGP
                     ELIERVVGYARFVRAAAAAGRAAGLTPLEAARETDLGEYAELTDPERIVGNLHRAYAEM
                     DGLEPGGRIDLAAALNDMIAYNGGRPLTCRA"
     gene            complement(967..1170)
                     /locus_tag="GNZ18_RS08050"
                     /old_locus_tag="GNZ18_08050"
     CDS             complement(967..1170)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GNZ18_RS08050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GNZ18_08050"
                     /product="hypothetical protein"
                     /protein_id="WP_156215529.1"
                     /transl_table=11
                     /translation="MTAREAVDGLNGLAAALAPRERPQVVIVVTGGYTPWPAEAPSRRR
                     DAPAPPSWVETVHPGPTPGSSP"
     gene            complement(1167..2774)
                     /locus_tag="GNZ18_RS08055"
                     /old_locus_tag="GNZ18_08055"
     CDS             complement(1167..2774)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024206.5"
                     /locus_tag="GNZ18_RS08055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_08055"
                     /product="ankyrin repeat domain-containing protein"
                     /protein_id="WP_156215530.1"
                     /transl_table=11
                     /translation="MTWTPLRADLVAALRIRRHAVPRSVIEKATERRLAGDWRGACAAA
                     NLDVAFELDDVADRFGAELASRLADDLPHFAPDLLRWHLPRAGGGQTTIAPRQVLGLAR
                     YGGGARAAALQVVTPRHVHGPQRPRLVVLPWSEETRDWTSAPHMFDARRSGDLLKYCGG
                     GDRAPFFHPDGTPLAPEELPASPPEGGPALHEWAVLAYERGDVEAAFDAVGIDFDLTGD
                     ERYPRWLNAATYASAPVAPALLAREIARHPGGPPPLWVAVRPYQELVVRAGGKRTRPLL
                     RPVSRGERAKRAVELPEHRWRRLPDLDLLRAGMATPDELHPLVAAALFPARPPASGPPG
                     MAPPAPTRVRCGGEWHEVMPGGLGLLMPHTAEERRSEAAPPAPGGRVQGCFAVQRMWRR
                     GGGWLPRSLREYRREVFLCVQHGDTEAVLRLLDEGLDPFVRDGRRRTLLHQIHLMDHEA
                     LLPRLLGAGLGLEDVDHEKRTPLHVAVGESGSPEVVRALVEAGARTGVRDSHGRSLQKM
                     IKGYGRTELEWLRDEPKR"
     gene            complement(2771..3922)
                     /locus_tag="GNZ18_RS08060"
                     /old_locus_tag="GNZ18_08060"
     CDS             complement(2771..3922)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634151.1"
                     /locus_tag="GNZ18_RS08060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_08060"
                     /product="gala protein"
                     /protein_id="WP_156215531.1"
                     /transl_table=11
                     /translation="MAPTPVRCPAIEHPDVPPADPAALDPLLARLAEGAPPEADEGFPL
                     GTLRRDGRVDLCKRGLGAAGVARLVPAAAASPHAAHLLLGTNAMGDAGARAIAGALAPG
                     HGVRTLYLGCNRVGADGAAALAGRLASDTRVRALWLKRNPVGDAGASALAAMLRTNQTI
                     RTLDLVNTGVGTAGLRALRDALAAREAPLERLFLGGNGLGPDAADLLAALLRDAGVREL
                     YVPVNHLGDGGAAILADAADAADAACAAGRPVRLGLGGNGVGPAGARALAAALGGIEAL
                     DLGRPPSERALGAPPNATGDEGAAALAEALPGSPIRRLELRHSGVTGRGAKALLARVGD
                     GTRLEHLGFGPGVPRRIKRAAAGFLRPAARAHPDMRAIVSVYR"
     gene            complement(3922..5316)
                     /locus_tag="GNZ18_RS08065"
                     /old_locus_tag="GNZ18_08065"
     CDS             complement(3922..5316)
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017569458.1"
                     /locus_tag="GNZ18_RS08065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_08065"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_312874370.1"
                     /transl_table=11
                     /translation="MPTVPAEDAPEPADLAACLRLLERARRAAPDDPRWKAVHEAASQV
                     HRSGKKARRTARAAERRRRDLAALASTTRFQDQNPSPEPAAAPESSAPSDGVRRTLVAA
                     RPCYVCKEPYRDVHPDYHLLCPACARENAERRHARCDLRGRRAVVTGGRVKIGFQVALK
                     LLRDGAEVLVTTRFPRDAARRFAAVGDHGDWIGRLHVHGVDLLDLPGVAGLLDAVHDRF
                     DHLDVLVNNAAQTVRRPPAYHREVRAAEALPLTGPAARVDVAEGARAALAPAHVAMAAL
                     TAREDALFPAGRTDETGEPLDLRERNSWSLRLHEIDPVEWAEVQMVNAFAPFLLTARLR
                     GLLERSPWPDRYVVQVSAMEGSFSRRSKTVRHPHTNMAKAALNMLTRTSAADYAAAGIH
                     MTSVDTGWVTDERPHPGRLAQRAAGFAPPLDVIDGAARVYDPVVRGVGGERLSGLFLKD
                     YRPVEW"
     tRNA            complement(5348..5420)
                     /anticodon=(pos:complement(825530..825532),aa:Leu,seq:cag)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="GNZ18_RS08070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="GNZ18_08070"
                     /product="tRNA-Leu"
     gene            complement(5348..5420)
                     /locus_tag="GNZ18_RS08070"
                     /old_locus_tag="GNZ18_08070"
     gene            complement(5485..6417)
                     /locus_tag="GNZ18_RS08075"
                     /old_locus_tag="GNZ18_08075"
     CDS             complement(5485..6417)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039603.4"
                     /locus_tag="GNZ18_RS08075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_08075"
                     /product="DUF5954 family protein"
                     /protein_id="WP_156215532.1"
                     /transl_table=11
                     /translation="MASEGMPGYDLINLVRDLGPVEAVRDQESAERMRVYPKIVGAGPP
                     DFGIAERSGGAWRIRHLGALEPYGARIDLAIHLRDTAVRHERRVREKMLAIADRCDPEV
                     GEPTTETDFAAGGRRYRIVRVLGFTRFGEDGPEPARPTDTEEGPLRSFLIDPTAPVGPS
                     DAALRLELLSLLPAAGTVPEAVRREAVAAIREHPGVVLLPPEFTVAEDLDDRWRPLTGG
                     DGPQDARDALAHYFRVILPRHAPGGGPPPSKGELAEYARAADQVDAERGVEFVACGRRF
                     RIVRVVRMVRVGPDGPEPARPSDEDPGDG"
     misc_feature    complement(6474..6487)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.52"
                     /tool="antismash"
     misc_feature    6509..6523
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 23.18"
                     /tool="antismash"
     gene            complement(6530..7582)
                     /locus_tag="GNZ18_RS08080"
                     /old_locus_tag="GNZ18_08080"
     CDS             complement(6530..7582)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0000902 - cell morphogenesis [Evidence
                     IEA]"
                     /GO_process="GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018435.5"
                     /locus_tag="GNZ18_RS08080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_08080"
                     /product="rod shape-determining protein"
                     /protein_id="WP_156215533.1"
                     /transl_table=11
                     /translation="MWDYAGRDTAIDFGSATVRMHVRGRGVVCREPSLLARSRRSGRIL
                     ALGVPAQQMAGRSPDVRLVRPIREGAPTETDEAEYLMRHLVRTHHRRHYMARPRLVMTV
                     PSGLSSVHYRALQFSAYQAGARRLTLVPTPIAAAAGMGLIESGPEIAVVADIGAEVTDV
                     GVIAFGGLVTSHTAHVGGTTLDRAIAALVRREHGVALSPAAAEAAKIAVGAVPRIGRHP
                     ARQTSVEGREVVSGLPRRLVLTTTDVQRAIEGPVARIVEAIRTGLGGCSPEISGELLSV
                     GVTLTGGSARLPGLDRLIRERTGLDAWLGDDTGDAAVIGAAGVLRAAGSPPSTRDITPH
                     PQPLTTVPQS"
     gene            complement(7789..9879)
                     /locus_tag="GNZ18_RS08085"
                     /old_locus_tag="GNZ18_08085"
     CDS             complement(7789..9879)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GNZ18_RS08085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GNZ18_08085"
                     /product="hypothetical protein"
                     /protein_id="WP_156215534.1"
                     /transl_table=11
                     /translation="MSTSTTAGGGRSGGNLPAGLPSFVGRAVELAELDGALEESPLVTL
                     TGVGGVGKTRTALEAARRARGRFPDGIWLVELSRLRDPVLLVPTVATTLRVHDPGTRPL
                     AEVLAGHLAGRSCLIVLDTCEHLTGACAALARALLAEAPRLRILATTRQPLGADGERVV
                     PLAPLPVDPGAKEEAGDAVRLFAERARHAVPGFAVDEANRDAVTRLCRRLDGLPLALEL
                     AAPWLRVLPVEAVADRLDDRFRMLARGPGHEPGRHESLRTAIGWSHELCGPAERLLWAR
                     ASVFAADFDRQTVQEVCAGGPLAAADLPRVLARLVHKSVLTCDGTGPHARYGMLDTVRE
                     YGARWLAELGEEQEIARRHRAFHLALARRAYAFWMGGRQIDWYERVRAVHPDVRAALEG
                     ALADPRDGDDAVELAGALWFYWYACGFQREGRHFLERALAVSSRPGLGRTRAAWARGLI
                     TLAQGDLTAADQCIEICRADTGRLAATAAEFLAGSAMTLRGENAEALRVLRALRPDPAR
                     GGVDEAIWFLERGVRAFAHVQLGQLDEAAAMARESRTRSAERGERCLQAWADYVHALAE
                     LGLGRPGDAAAHARDALVAKRPLNDTWFLALCVDALSLALAATGEAEPAARLIGVGQRL
                     WRSHGLPQLGAPELVAAREECERGLRCALGDAAYDAAHTAGLRMPTEDGLDYALAAFGP
                     PS"
     gene            complement(10001..11107)
                     /locus_tag="GNZ18_RS08090"
                     /old_locus_tag="GNZ18_08090"
     CDS             complement(10001..11107)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.5"
                     /locus_tag="GNZ18_RS08090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_08090"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_156215535.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.4e-41, bitscore:
                     137.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATEAPAAPTGAAAPPGAAPPAAAPAPPLGAAFEPEHLALFEPA
                     LSAAVHRLPAAVRRVAGYHLGWWDEDERPLFGPDATDEAATIRPALALLCGEAAGGRAS
                     SALPAAVAVELAHHFSLLHDDIMDGGGTRRRRPAAWTVFGAAQALLTGDSLMVAAMDVL
                     AAASRDIAPRALHDLAAGLQDLGAGRSAELRLASAPAPTPDDCREVIAGKTASLLGCAC
                     SLGTMFGGGSPERVRLMRMFGERLGHAAHLAEDMRGVWGDPPGTGGAAHRDLARRKRSL
                     PVVAALASGTAEGRELAAAFETGAEFSPAVLAHLAGLVERTGARRLAAGLAAENLAGAA
                     ACLDAAGPPPGPAAALRAVLDRVAARIP"
     misc_feature    complement(11268..11278)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            11377..12249
                     /locus_tag="GNZ18_RS08095"
                     /old_locus_tag="GNZ18_08095"
     CDS             11377..12249
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.4"
                     /locus_tag="GNZ18_RS08095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_08095"
                     /product="terpene synthase family protein"
                     /protein_id="WP_156215536.1"
                     /sec_met_domain="T1TS (E-value: 1e-10, bitscore: 37.1,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYRSADACPGLDVLAAADAAVAAARLTARAAAWARRLGPPLDPA
                     LAPLCGMPAAFVAPWTSRPAADLTARTGLWIFALDAWTDGPAARRDPAALRRGLADLRA
                     VAAGAAGSGPLGEGLAEIRDGIAAAPDAPGPWRRSVDAALAGALFEYEAARRVTAGGPP
                     PPLREYLRHGAASVALAPLVLAMWSGMACPEPVLRALEGPLRDACLAVRLANDLSGHRR
                     ERAEGVLDALSLGMSPGEARARSAECVARCRRALRPHIGPVPGPALALERQLLWAVRHY
                     ERVDAGHAA"
     gene            12246..13754
                     /locus_tag="GNZ18_RS08100"
                     /old_locus_tag="GNZ18_08100"
     CDS             12246..13754
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024640.5"
                     /locus_tag="GNZ18_RS08100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_08100"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_156215537.1"
                     /sec_met_domain="T2TS (E-value: 1.6e-71, bitscore: 236.9,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGRNVRASLLARAETLLDGLGEGGSFSPCPYTTAWLSRLRDRDR
                     VLFPLARRWLLDRQRADGSWGAVIGLPHDRTVCTLAAVMALTDPGPPLPGRAEAVRAGL
                     AYLRAHSTAWRAADVGETIGFELAVPFLLGQASARGLDLPYGDWDELAKTRRAKLDLIP
                     RDRLLREPTSLMYSLEAVDPGPALRGLARFAGPDGSLANSPSATAALWAAGPHGGMPAY
                     LKNVEMPDGGVPSLYPTEAFELAWALHHLQRGGLLDMRAPSAARRVARLRALLGPRGHL
                     GLSGGFPLPDPDDTAMAIIVLHAAGRGVPHLLDALLDFEGEHCFFTYPGERDGSVTPNA
                     RVLEALALRPAAYTRPMAKIVEFLLDTRREDAWWYDKWHASPYYATAQVTFALTRASTL
                     PLEGTLAWLLATQRPDGSWGWYGTGTPEETGCAVLNLDALARHGMRVPRSAWVGAHRYL
                     RNHLDGPFPELWVGRSLYTPRDVSSSTVLAGAALAAARTAPSGA"
     gene            complement(13741..15084)
                     /locus_tag="GNZ18_RS08105"
                     /old_locus_tag="GNZ18_08105"
     CDS             complement(13741..15084)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.5"
                     /locus_tag="GNZ18_RS08105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_08105"
                     /product="cytochrome P450"
                     /protein_id="WP_156215538.1"
                     /sec_met_domain="p450 (E-value: 2.5e-69, bitscore: 229.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLLIGRHGPGVPRGPGGSAVARRLVRDPVGLLQDLREVGPVVVV
                     RLGTVPVYLVNAPDPLRRMLVTDAGSFVRGRAYDRARPVLGGGLATADGDAHLRRRRLM
                     MPSFHRARLLGYTGVLREQAEVLAGSWRDGQRVELDVALHRASAAGALRALLRADLDEA
                     TVAEIDHCVTVFLREIPLRAVLPRFATRLPLPGNRRFARVAARLREIVDGMVEERRRDP
                     GERDDLLSLLMDARDEDTGAAMSAAQLRDELVTILAGGSETVPTTLSWLYHELGRNPEM
                     QARLQEELDAVLGGRPVEFDDLPHLRYTRRLIDETLRLHSVAWMMSRRARVDVDLGGYR
                     IPAGAELLYSPTTFHRDPVLYPEPLRFDPDRWLSPPPREHFVPFGAGPRKCIGDHFSYI
                     QLSVIVASVSARWSVAPAPGAEVRERVAGALRPDRLPMLVSRRTATRR"
     gene            15340..16173
                     /locus_tag="GNZ18_RS08110"
                     /old_locus_tag="GNZ18_08110"
     CDS             15340..16173
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012888319.1"
                     /locus_tag="GNZ18_RS08110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_08110"
                     /product="PP2C family serine/threonine-protein phosphatase"
                     /protein_id="WP_156215539.1"
                     /transl_table=11
                     /translation="MTHHVLRFAAGTHTGRQRTVNEDSAFASPGLLAVADGMGGHPHGD
                     VASRTAITVLAEAAPHRAAGREGGDPGPALASAVTDIAARLDDLGRHDPDLARMGTTLT
                     ALAWDGAGFAVAHIGDSRAYVLRGGVLERITRDHTMVQILVDEGRLTPEQAARHPRASV
                     LVRALQSGARAQPDLYHREARPGDRYLLCSDGVSGVIPDEAIRDALDAPAPEEAVDRLV
                     ALANGAGGPDNITCVVADVVPEAADADTQSPELLGAAAHAPTGPLARLGRRLRRA"
     misc_feature    complement(16177..16192)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.45"
                     /tool="antismash"
     gene            16371..18173
                     /locus_tag="GNZ18_RS08115"
                     /old_locus_tag="GNZ18_08115"
     CDS             16371..18173
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131107.1"
                     /locus_tag="GNZ18_RS08115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_08115"
                     /product="N-6 DNA methylase"
                     /protein_id="WP_156215540.1"
                     /transl_table=11
                     /translation="MSDDPGVTAGDIARIAGVGRATVSNWRRRHADFPRPVGGTAASPL
                     FSLTDVEGWLIRNGKPFEVSLGDRVWQRLRASADDFRLADLVGWAGLRLLGDRGDATGP
                     SQPAIIPGDPELPGMLKDLAAEYGHRGAFELIFERYAAAHSRRLVLTRGDVARLMTRLA
                     CREGDTVLDPACGLGTLLLAAPGAGRVLGQESDPAAARIALLRLLLARTPAEIVAADSL
                     RADGFAEEAADSAVCNPPFGDRAWGHEDLTGDPRWEYGLPPRGEPELAWVQHCLAHVRP
                     GGRAALLMPSAVASRRPGRRVRGNLLRTGALRAVATLAPGGPDLWLLRRPGPGERPPER
                     ILLLDAEGDLDRVEREWNRHVDGGGEWSVPVVDLLDDEVDVTPSRHRPRHSGPAFGRRF
                     SEALDRLAAAAPEPPRVDLLPEQRPLPFTTIAELARAGVLTVIHAPARPLTGGAVPVLT
                     VDDLTTGSDPSGAAAPDPSLIRLQPGDVVATAAGSARVIAEPGAVLGPHLTLYRPDGAR
                     LDPHFLAGFLTFAHTRTGTGSSRMDLRRTRIPRLSLERQREYGRAFQELARLTATLREM
                     SALGDALVRLSFDGLVDGHLRPRR"
     gene            18192..19091
                     /locus_tag="GNZ18_RS08120"
                     /old_locus_tag="GNZ18_08120"
     CDS             18192..19091
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546768.1"
                     /locus_tag="GNZ18_RS08120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_08120"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_156215541.1"
                     /sec_met_domain="Pkinase (E-value: 3e-47, bitscore: 156.6,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 1.4e-07, bitscore: 27.1,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLIADRYELDDLPLGRGGMGAVYAADDTRLGRRVAVKFLQLPGGP
                     DDELERRFIREARILARLEHAGAPTLYDFGTFEQRLYQVMQFIDGVTVADLIAEHGPVP
                     VAWAAGITAQAAAVLAAAHALSIRHRDLKPTNLMLCPDGSVKVLDFGLAVLGDADVAHF
                     TRHGQILGTPAYMAPEQIEQGVADPRSDLYALGCVLHEMLTGRQLFAGPTAYAVFDKHV
                     REQPPPIQGIPSELNYLVQDLLEKKPENRPPDAPSLYERVRPFATDLPLLPGFLEPAST
                     SSPERMYALIVGQALRPR"
     gene            complement(19155..20648)
                     /locus_tag="GNZ18_RS41115"
     CDS             complement(19155..20648)
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013073.5"
                     /locus_tag="GNZ18_RS41115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="C40 family peptidase"
                     /protein_id="WP_216651197.1"
                     /transl_table=11
                     /translation="MCEARQSGRPNDRPRAFPGRPRHGGTTERKRRTLRRAATVTAVGL
                     ALSLPAGTQALAALNPVVLKRLDLDAVTLGKVKAYDRYRTREARQKTKARKALTFARKQ
                     IGKPYSWGAAGPARYDCSGLAMAAWRRAGVKIPRVTYSQYSGVRRKVAFKDLRPGDLIF
                     FHGRSHVGIYVGHGRFLHAPNSRSRVRIDRLGAARKRQFAGAVRPGAPAYKKWSPSIRE
                     LVEKIDRMSAQEKAHKAPETTADSPLGLPPGIILRTTPAKPAPPANEAAATQSQWPTPP
                     YNDAPATHQAPLVNEPTPADETAPTSEETSAEEAAPTQDSPPIEAGSPANQADDASPAA
                     APPANDAAQPENAESTEDGAAPNNGAAQPENTAHAHNAAHANSAPHAAATHSHDAAAVA
                     DGAVAEAENAHHANEQALAQEAAALDGSGAGTPGRRERRPVPPRGVSRPVHEVTMHEVK
                     APVGTHEGHGRPANLAAAQPRPAVLAKGERPVAHTAARS"
     misc_feature    complement(20706..20719)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.76"
                     /tool="antismash"
     misc_feature    20737..20750
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.04"
                     /tool="antismash"
     misc_feature    20783..20798
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.56"
                     /tool="antismash"
     gene            complement(20787..22196)
                     /locus_tag="GNZ18_RS08130"
                     /old_locus_tag="GNZ18_08130"
     CDS             complement(20787..22196)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853904.1"
                     /locus_tag="GNZ18_RS08130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_08130"
                     /product="phosphotransferase"
                     /protein_id="WP_173390648.1"
                     /sec_met_domain="APH (E-value: 2.8e-08, bitscore: 29.4,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLPPRSVLQRDLAEWLPRQRWFGGKHIPIDGITIAATTELHSGDP
                     ALHHLVIHVRQHTGTDRYQLLLGTRRDLPDRLRHAEIGGSPEEGTHCYDAAHDPDLTRT
                     LLRGLAAEASVGPLRFRNAGGGVIRTDLTSLPITAEQSNTSLLFGDAYICKLFRRLSDG
                     VNPDLEVNLALTRGGCAHVPAVLGWIELEPGEGGEPTTLALLSTYLRTGADGWSLAIAS
                     VRDWYAHTMPPGGDEWAELDASAAGGDFAAEAERLGAATARVHQALAGAFGVTTLPAGE
                     VHAMAARMNEDLTETCRAVPALAPHAKALTGAFLDLATRAAPLPVQRVHGDYHLGQVLR
                     TESGWTVLDFEGEPARTPGERRALAHPLRDVAGMLRSFEYAARFLITKAGALPPESGRR
                     LETRAHAWAARNRAAFCRGYAAAGGVDPAAHAVLTRAFEFEKAVYEVRYEARNRPAWLP
                     VPLRSLAHLTT"
     CDS             complement(22199..>22571)
                     /codon_start=3
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017537206.1"
                     /locus_tag="GNZ18_RS08135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_08135"
                     /product="alpha-glucosidase C-terminal domain-containing
                     protein"
                     /protein_id="WP_173390681.1"
                     /transl_table=11
                     /translation="GSLLHWTRTMIEIRQRHPVFGVGTYNELSASNPSVLAFTREIGEK
                     EADQWGGTDVILCVSNLSRFPQPVELDLRRFEGHSPVECTGGVQFPAIGELPYLMTLPG
                     HGFHWFQLTPPEDADTERTA"
     gene            complement(22199..>22575)
                     /locus_tag="GNZ18_RS08135"
                     /old_locus_tag="GNZ18_08135"
ORIGIN
        1 gggctactcg gttacttctg agtagtactc gtcaggcgcg gcaggtcagc ggtcgtccgc
       61 cgttgtaggc gatcatgtcg ttgagcgcgg cggccaggtc gatgcgcccg ccgggctcca
      121 acccgtccat ctcggcgtag gcgcggtgca ggttgccgac gatccgctcg gggtcggtca
      181 gctccgcgta ctcgccgagg tcggtctccc gcgcggcctc cagcggcgtc agccccgccg
      241 cccggcccgc cgccgccgcg gcccgcacga accgcgcgta gccgaccacg cgctcgatca
      301 gctcgggccc ggcgaccggc ccgtgcccgg gcacgatcgt ctccgcctcc agcggcgcga
      361 tcacctcggt cagcaccctg atcgcgccgt ccaccgagcc ctgcatcagg aacggtgtgc
      421 cgccgttgaa cagcaggtcg ccgcagaaca gcacccgccg ctcggggatc cacacgatcg
      481 agtcgttggt ggtgtgcgcg ggcgtcccga cgtgccggac ctcgcagcgc aggtcgtcca
      541 cccacagcgt cacgccgtcg gcgtaggtga ggaacggcgg ctccaactcg acgccgcccc
      601 actcgacctt cgtccagaac ggctcgtcga acggcatccc ccagtcgagc gcgccctgcc
      661 gggtgccctc gtgcccgacg acggtcgcgc cggagaacag gtagttgccg aacgtgtggt
      721 cgccgtggtg gtgggtgttg accagcgtcc ggacgggacg cggcgtcacc gacccgatcg
      781 cctccaggta ggcgcgggtg cggcgctcgg tcgagcacgc gtcgacgctc gtcacgccgc
      841 gcgcccccac caggaagccg gtgttgttga tccaccaggt gccgtccggc tggaggtagg
      901 cgaagatccc gtcggacacc tccaccagcc gggggtcgcc ggggccgtcg aggtcgggcg
      961 cgtcgctcat ggggaactcc cgggtgtcgg gcccgggtgg acggtctcca cccaggacgg
     1021 aggggcaggg gcgtcgcgcc ggcgggaggg cgcctcggcg ggccacggag tgtatccgcc
     1081 ggtgacgacg atcaccacct gcggccgctc gcgcggcgcg agcgcggcgg cgaggccgtt
     1141 cagcccgtcg accgcctccc gggcggtcat cgctttggtt cgtcgcggag ccactccagc
     1201 tccgtccggc cgtacccctt gatcatcttt tggagcgatc ttccgtggct gtcgcgtaca
     1261 ccggtgcgcg cgcccgcctc gaccagcgcg cggaccacct ccggcgaacc ggactcgccc
     1321 accgcgacgt gcagcggggt ccgcttctcg tggtcgacgt cctccaggcc gagcccggcg
     1381 cccagcagcc tcggcagcag cgcctcgtgg tccatcagat ggatctggtg cagcagcgtg
     1441 cgcctgcgcc cgtcccggac gaacgggtcg agcccctcgt ccagcagccg cagcacggcc
     1501 tcggtgtcgc cgtgctgcac gcacaggaac acctcccgcc ggtactcgcg cagcgagcgc
     1561 ggcagccacc cgccgccccg ccgccacatc cgctggacgg cgaagcagcc ctgaacgcgc
     1621 ccgcccggcg cgggcggcgc cgcctcactc cgccgctcct cggccgtgtg cggcatcagc
     1681 agcccgagac cgcccggcat gacctcgtgc cactcgcccc cgcaccgcac cctcgtcggc
     1741 gcgggaggcg ccattcccgg cgggccggag gcgggcggac gggccgggaa cagcgccgcc
     1801 gcgacgagcg ggtgcagctc gtccggcgtg gccatcccgg cgcgcagcag gtcgaggtcg
     1861 ggcagccggc gccaccggtg ctcgggcagc tccacggccc gcttcgcccg ctccccgcgc
     1921 gacacgggcc gcaggagcgg gcgcgtgcgc ttcccgcccg cccgcacgac cagctcctga
     1981 tacggccgta ccgccaccca caggggaggc ggcccgccgg ggtggcgggc gatctcgcgc
     2041 gcgagcagcg cgggcgccac cggcgccgac gcgtacgtcg ccgcgttgag ccagcgcgga
     2101 taccgctcgt cgccggtcag gtcgaagtcg atcccgacgg cgtcgaaggc ggcctcgacg
     2161 tcgccgcgct cgtaggcgag gaccgcccac tcgtggagcg cgggcccgcc ctcgggcggg
     2221 gacgcgggca gctcctccgg cgccagcggc gtgccgtccg ggtggaagaa gggcgcgcgg
     2281 tccccgccgc cgcagtactt gagcaggtcc ccggaccggc gggcgtcgaa catgtgcggc
     2341 gccgacgtcc agtcccgagt ctcctcggac caggggagca cgacgagccg cggccgctgc
     2401 ggcccgtgga cgtggcgcgg cgtgaccacc tggagggcgg ccgcgcgggc gcccccgccg
     2461 tagcgcgcca ggccgagcac ctgccgggga gcgatggtcg tctggccgcc gccggcccgg
     2521 gggaggtgcc agcgcagcag gtcgggcgcg aagtgcggca ggtcgtcggc gagccgggac
     2581 gcgagctcgg cgccgaacct gtccgcgaca tcgtccagct cgaacgccac gtcgaggttc
     2641 gccgccgcgc acgccccgcg ccagtcgccc gccagcctcc gctcggtggc cttctcgatc
     2701 accgagcggg ggacggcgtg ccggcggatc cggagcgcgg cgaccaggtc cgcccgaagg
     2761 ggcgtccagg tcatcggtag acgctcacga tcgcgcgcat gtccgggtgg gcgcgggcgg
     2821 cggggcgcag aaacccggcg gcggcccgct tgatccggcg cggcacgccc ggcccgaacc
     2881 cgaggtgctc aagccgcgtc ccgtcgccga cccgcgcgag cagggccttg gcaccgcgcc
     2941 cggtgacgcc gctgtgccgc agttcgaggc ggcggatcgg gctgccgggc agcgcctcgg
     3001 ccagcgccgc cgccccttcg tcgccggtcg cgttgggcgg cgcgccgagc gcgcgttccg
     3061 acggcgggcg gccgaggtcg agcgcctcga tcccgccgag cgccgccgcg agggcccgcg
     3121 ccccggcggg cccgacgccg ttcccgccga gcccgagccg gacggggcgc cccgccgcgc
     3181 acgccgcgtc cgccgcgtcc gccgcgtccg ccaggatcgc cgcgccgccg tcgcccagat
     3241 ggttcaccgg cacgtacagc tcgcggacgc ccgcgtcgcg cagcagcgcg gcgagcaggt
     3301 ccgccgcgtc cgggccgagc ccgttgccgc cgaggaacag ccgctccagc ggcgcctcgc
     3361 gcgccgccag cgcgtcgcgg agggcgcgca gcccggccgt ccccaccccg gtgttgacca
     3421 ggtcgagcgt ccggatggtc tggttggtcc gcagcatcgc ggcgagcgcc gaggcgcccg
     3481 cgtcgcccac cgggttgcgc ttcagccaca gcgcccgcac ccgggtgtcg gaggcgagcc
     3541 gcccggccag cgccgccgcg ccgtccgcgc cgacccggtt gcagccgagg tagagcgtgc
     3601 ggacgccgtg gccgggggcg agggcgccgg cgatcgcccg cgcgcccgcg tcgcccatcg
     3661 cgttcgtgcc gagcagcagg tgcgccgcgt gcggggacgc ggcggccgcc gggacgagcc
     3721 gcgcgacgcc cgccgcgccg aggccccgct tgcacaggtc cacgcgcccg tcgcggcgca
     3781 gcgtcccgag cgggaagccc tcgtcggcct ccggcggcgc gccctcggcg agccgcgcca
     3841 gcagcgggtc gagcgcggcc gggtcggcgg gcggcacgtc cgggtgctcg atcgcggggc
     3901 agcgcacggg ggtcggggcc atcaccactc caccggtcgg tagtccttca ggaacagccc
     3961 ggacagccgc tcgccgccga cgccccgcac gaccgggtcg tacacgcggg cggcgccgtc
     4021 gatcacgtcc agcggcggcg cgaaccccgc cgcccgctgc gcgagcctgc ccggatgcgg
     4081 gcgctcgtcg gtcacccagc cggtgtcgac gctggtcatg tggatgcccg ccgccgcgta
     4141 gtcggccgcg gacgtgcggg tcagcatgtt cagcgccgcc ttggccatat tggtgtgcgg
     4201 gtggcggacg gtcttgctcc ggcgggagaa gctgccctcc atcgccgaca cctgcacgac
     4261 gtaccggtcg ggccacgggg agcgctccag cagcccgcgc agccgcgccg tcagcaggaa
     4321 cggcgcgaac gcgttcacca tctgcacctc ggcccactcg accgggtcga tctcgtgcag
     4381 ccgcaggctc cagctgttgc gctcgcgcag gtcgagcggc tcgccggtct cgtccgtgcg
     4441 gccggcgggg aacagcgcgt cctcgcgggc ggtgagcgcc gccatcgcga cgtgcgccgg
     4501 ggcgagggcc gcgcgggcgc cctccgcgac gtccacccgc gcggccgggc cggtcagcgg
     4561 cagcgcctcc gccgcgcgca cctcccggtg gtaggcgggc ggccgccgga cggtctgcgc
     4621 cgcgttgttg accaggacgt ccagatggtc gaaccggtcg tgcaccgcgt ccagcagccc
     4681 cgccacgccc ggcaggtcga gcaggtccac gccgtggacg tgcagccgcc cgatccagtc
     4741 gccgtggtcg ccgaccgccg cgaaccggcg cgccgcgtcg cgcgggaacc gggtggtgac
     4801 cagcacctcc gcgccgtccc gcagcagctt cagcgcgacc tggaagccga tcttcacgcg
     4861 cccgcccgtc acgacggcgc ggcgcccgcg caggtcgcag cgcgcgtgcc ggcgctccgc
     4921 gttctcccgc gcgcacgccg ggcacagcag gtggtagtcg gggtggacgt cgcggtaggg
     4981 ctccttgcac acatagcagg gccgcgccgc cacgagcgtc cgccgcacgc catccgatgg
     5041 cgcgctggac tcgggggcgg ccgccggctc gggcgagggg ttctggtcct ggaagcgggt
     5101 cgtggacgcg agcgcggcga ggtcgcggcg gcggcgctcg gcggcgcggg ccgtccggcg
     5161 ggccttcttg cccgagcggt gcacctgcga cgcggcctcg tgcaccgcct tccagcgcgg
     5221 atcgtccggg gcggcgcgcc gcgcccgctc cagcagccgc aggcatgcgg cgaggtcggc
     5281 cggttccggc gcatcctcgg ccgggacggt cggcacggcg ctcctcgctg cccggggacg
     5341 gatggggcag agccgaccgg attcgaaccg gcgtcctcca gcgagctgcg gtggcgcgac
     5401 gacctctgcg ctacggccct gccgtgcggc agcctagcga agcacccggc gctccgcccc
     5461 ccggatccgg cgcgaagatc gcgttcagcc gtcgcccggg tcctcgtcgg aggggcgggc
     5521 gggctcgggc ccgtccgggc cgacccggac catccgcacc acgcggacga tgcggaaccg
     5581 ccgcccgcac gccacgaact ccacgccccg ctcggcgtcg acctggtcgg cggcgcgcgc
     5641 gtactcggcc agctcgccct tgctcggcgg cggcccgccg cccggcgcgt ggcgcggcag
     5701 gatcacgcgg aagtagtgcg cgagcgcgtc ccgggcgtcc tgcgggccgt cgccgccggt
     5761 gagcggccgc cagcggtcgt cgaggtcctc ggcgacggtg aactccggcg gcagcagcac
     5821 cacgcccgga tgctcgcgga tcgcggcgac cgcctcccgg cgcaccgcct ccgggaccgt
     5881 cccggcggcg ggcagcaggc tcagcagctc cagccgcagc gccgcgtccg acggcccgac
     5941 cggcgcggtc gggtcgatga ggaacgagcg cagcgggccc tcttcggtgt cggtcgggcg
     6001 cgcgggctcc gggccgtcct cgccgaaccg ggtgaagccc agcacccgga cgatccggta
     6061 ccggcgcccg cccgccgcga agtcggtctc ggtcgtcggc tcgcccacct cggggtcgca
     6121 ccggtcggcg atcgcgagca tcttctcccg gacgcgccgc tcgtggcgta cggcggtgtc
     6181 gcgcaggtgg atcgcgaggt cgatccgcgc cccgtagggc tccagcgcgc cgagatgccg
     6241 gatccgccac gcgccgccgg agcgctcggc gatgccgaag tccggcggcc ccgcgcccac
     6301 gatcttgggg tacacgcgca tccgctcggc ggactcctgg tcgcggaccg cctcgacggg
     6361 cccgagatcc cggacgaggt tgatcaggtc gtatccgggc atgccctcgc tggccatgca
     6421 cccatcgtgg cgccgcggcc gccgcgccgc gccccaaacg accgcacggt caccgaacac
     6481 atgctcgtca tgcggccttt tcccgttttg ggaggggtct catcgagggt caggactgcg
     6541 ggacggtcgt cagcggctgc ggatgcggcg tgatgtcgcg ggtggagggc ggcgatccgg
     6601 cggcgcgcag cacgcccgcg gcgccgatca ccgccgcgtc gccggtgtcg tcgccgagcc
     6661 aggcgtccag cccggtccgc tcgcggatca gccggtccag gccgggcagc cgcgccgaac
     6721 cgccggtcag cgtcacgccg acgctgagca gctcgccgga gatctcgggg gagcagccgc
     6781 cgagcccggt ccggatcgcc tcgacgatcc gcgcgacggg cccctcgatg gcgcgctgca
     6841 cgtcggtggt ggtgaggacc agccgccggg gcagcccgga gacgacctcc cgcccctcca
     6901 cgctcgtctg ccgcgcggga tgccgcccga tccgcggcac cgcgccgacc gcgatcttcg
     6961 cggcctcggc ggcggcgggc gacagcgcca ccccgtgctc gcgccggacg agcgcggcga
     7021 tcgcgcggtc cagcgtggtg ccgccgacgt gcgcggtgtg cgaggtgacc agcccgccga
     7081 aggcgatcac gccgacgtcg gtgacctccg cgccgatgtc ggcgacgacc gcgatctcgg
     7141 gcccggactc gatcagcccc atcccggcgg cggcggcgat cggcgtcggc acgagcgtga
     7201 ggcggcgcgc gcccgcctgg taggcggaga actggagggc ccggtaatgg acggacgaca
     7261 gcccgctcgg cacggtcatg accagccggg gccgcgccat gtagtggcgc cggtggtggg
     7321 tgcggacgag atggcgcatc aggtactcgg cctcgtcggt ctcggtcggc gcgccctcgc
     7381 ggatcggccg caccagccgc acgtcggggc tccgccccgc catctgctgg gccgggacgc
     7441 ccagcgcgag gatccgcccg ctgcgccgcg agcgggccag cagcgacggt tcgcggcaga
     7501 cgacgccgcg gccccggacg tgcatccgca cggtcgcgct gccgaagtcg atcgccgtgt
     7561 cccggcccgc gtagtcccac atcctcgcgt ccccccgatc gcccggaatg cccacggatt
     7621 cctgtcatgc cccgggtgtc cggggcaatg cccaccgccg ggtaagcgaa tggcaacggc
     7681 acggcgaacg cggatccgga atgtcggaca ggggcgggga gccgttcccc gtgcccgcgc
     7741 cgcaaccccg tgccgagccc aagagatcat cagctccgcc cccgcgggct aggagggcgg
     7801 gccgaacgcg gcgagggcgt agtcgaggcc gtcctcggtc ggcatgcgca gcccggcggt
     7861 gtgggcggcg tcgtaggccg cgtccccgag cgcgcaccgc aggccccgct cgcactcctc
     7921 gcgcgccgcg accagctcgg gcgcgccgag ctggggcagg ccgtgcgagc gccacagccg
     7981 ctgcccgacc ccgatgagcc gcgccgcggg ctcggcctcc ccggtcgcgg cgagggccag
     8041 cgacagcgcg tccacgcaga gggcgaggaa ccaggtgtcg ttcagcgggc gcttggccac
     8101 cagcgcgtcg cgcgcgtgcg cggcggcgtc accgggacgg ccgaggccca gctccgccag
     8161 cgcgtgcacg tagtcggccc acgcctggag gcagcgttcg ccgcgctcgg cgctgcgcgt
     8221 ccgcgactcc cgcgccatcg ccgccgcctc gtcgagctgc ccgagctgga cgtgcgcgaa
     8281 cgcgcggacg ccgcgctcca ggaaccagat cgcctcgtcg acgccgccgc gcgccgggtc
     8341 gggccgcagc gcccgcagca cgcgcagggc ctcggcgttc tcgccgcgca gcgtcatcgc
     8401 cgacccggcc aggaactcgg cggccgtcgc ggcgagccgc ccggtgtccg cgcggcatat
     8461 ctcgatgcac tggtcggcgg ccgtgaggtc gccctgggcg agggtgatca gcccgcgcgc
     8521 ccacgccgcg cgcgtccgcc cgaggccggg cctggaggag acggcgagcg cccgttcgag
     8581 gaagtggcgc ccctcgcgct ggaacccgca cgcgtaccag tagaaccaga gcgcgcccgc
     8641 cagctcgacc gcgtcgtcgc cgtcgcgcgg gtcggcgagg gcgccctcca gcgccgcccg
     8701 cacgtccggg tggacggccc ggacgcgctc gtaccagtcg atctgccggc cgcccatcca
     8761 gaaggcgtag gcgcggcggg ccagcgcgag gtggaaggcg cggtgccgcc gcgcgatctc
     8821 ctgctcctcg cccagctccg ccagccaccg cgcgccgtac tcgcggacgg tgtcgagcat
     8881 cccgtagcgg gcgtgcggcc ccgtcccgtc gcacgtgagg accgacttgt gcaccagccg
     8941 ggccagcacc cgcggcaggt cggcggcggc gagcggcccg cccgcgcaca cctcctggac
     9001 ggtctgccgg tcgaagtccg ccgcgaacac cgacgcccgc gcccacagca gccgctcggc
     9061 gggcccgcac agctcgtggc tccagccgat cgccgtccgc aggctctcgt gccggcccgg
     9121 ctcgtggccg gggccccggg cgagcatccg gaaccggtcg tcgagccggt cggcgacggc
     9181 ctccaccggc agcacccgca gccagggggc ggccagctcc agcgcgagcg gcagcccgtc
     9241 cagccgccgg cacagccgcg tgacggcgtc gcggttcgcc tcgtccaccg cgaagccggg
     9301 gacggcgtgc cgggcccgct cggcgaacag ccgcaccgcg tcgcccgcct cctccttggc
     9361 gccggggtcg accggcagcg gcgcgagcgg gacgacgcgc tcgccgtcgg cccccagcgg
     9421 ctgccgggtc gtcgcgagga tccgcagccg gggggcctcc gccagcagcg cccgcgcgag
     9481 cgccgcgcac gcgccggtga ggtgctcgca ggtgtccagg acgatcaggc aggagcggcc
     9541 cgccaggtgc ccggccagga cctcggccag cggccgcgtc cccgggtcgt ggacgcgcag
     9601 cgtcgtcgcg accgtcggga cgagcagcac cgggtcgcgc agccgggaca gctcgaccag
     9661 ccagatcccg tcggggaagc ggccccgggc gcgccgcgcc gcctccagcg cggtgcgcgt
     9721 cttgccgacg ccgccgaccc ccgtcagggt gaccagcggc gactcctcca gcgcgccgtc
     9781 cagctcggcc agctccacgg cccggcccac gaagctcggc agccccgcgg gcaggttccc
     9841 gccgctccgc ccgccgcccg ccgtcgtcga tgtgctcatc tcgcgccacc gttccgcgtt
     9901 ccttcgggac tctcgacggt agccgcgcga cagcgcgcgg taaggcgaac gtccgaaccc
     9961 ggcccgactc ctttgccctg ggggtgggcg ggcgcggtgg tcaggggatc ctcgcggcga
    10021 cccggtcgag gacggcgcgc agcgccgcgg cgggcccggg cggggggccg gcggcgtcca
    10081 ggcaggccgc cgcgcccgcc aggttctcgg cggccagccc cgccgcgagc cgccgcgcgc
    10141 cggtccgctc gacgagcccg gcgaggtggg ccagcacggc gggggagaac tcggcgcccg
    10201 tctcgaaggc ggcggccagc tcgcgcccct ccgcggtgcc ggaggcgagt gccgccacga
    10261 ccggcagcga ccgcttccgg cgggccaggt cgcggtgggc ggcgccgccg gtcccgggcg
    10321 ggtcgcccca gacgccgcgc atgtcctcgg cgaggtgggc ggcgtggccg agccgctcgc
    10381 cgaacatccg catcagccgc acccgctcgg ggctcccgcc gccgaacatc gtcccgagcg
    10441 agcaggcgca gccgagcagc gacgcggtct tgcccgcgat cacctcgcgg cagtcgtcgg
    10501 gcgtcggggc gggcgcggag gccagccgca gctcggcgct ccgtccggcg ccgaggtcct
    10561 ggaggcccgc cgcgaggtcg tgcagggccc gcggcgcgat gtcgcgggag gccgcggcga
    10621 ggacgtccat cgccgccacc atgagcgagt cgccggtcag cagcgcctgc gcggcgccga
    10681 acaccgtcca ggccgccggc ctgcgccggc gcgtcccgcc gccgtccatg atgtcgtcgt
    10741 gcagcaggga gaagtggtgg gccagctcca ccgcgaccgc cgccgggagc gcgctgctcg
    10801 cccggccgcc cgcggcctcc ccgcacagca gcgccagcgc cgggcggatc gtggccgcct
    10861 cgtcggtggc gtccggtccg aacagggggc gctcgtcctc gtcccaccag ccgaggtggt
    10921 agcccgcgac gcggcggacg gcggcgggca ggcggtgcac ggcggcgctg agcgcgggct
    10981 cgaacagcgc gaggtgctcg ggctcgaacg cggcgccgag cgggggagcg ggcgctgcgg
    11041 cgggtggagc ggctccgggg ggcgcggcgg ctccggtggg cgctgccggt gcctcggtcg
    11101 ccgtcatgtt cgatcccctc catcgtccgc cctgtaggtc agggccaccg tattcggaac
    11161 catccagaac aacggggaga gacatggccg atccggctgg gattgccttt ccatgaccgt
    11221 cgccatacct gccgacaacc tggcaaaggt cctggagtaa agggacggtg acctggcaaa
    11281 acagcgctcc ggacacggtt gttaccggtt agatcggagg tgtcgcagcg atgttcctga
    11341 cgtatcgatg gcatgaatag gggagtagcg cactcaatgg actacaggtc agcggacgcg
    11401 tgcccgggtc tggacgttct cgccgctgcg gacgcggccg tcgccgccgc ccggctcacc
    11461 gcccgcgccg ccgcgtgggc gagacggctc ggcccgcccc tggaccccgc gctcgcgccg
    11521 ctgtgcggga tgcccgccgc gttcgtcgcg ccctggacgt cgcgccccgc cgccgacctg
    11581 accgcccgca ccggcctgtg gatcttcgcg ctggacgcct ggaccgacgg cccagccgcc
    11641 cgccgcgacc ccgccgccct gcgccgcggc ctggcggacc tgcgcgccgt cgccgccggg
    11701 gccgccggtt ccggtccgct gggggagggg ctcgcggaga tccgggacgg gatcgccgcc
    11761 gcaccggacg cgccgggccc gtggcgccgg tccgtggacg cggcgctggc cggggcgctg
    11821 ttcgagtacg aggccgcgcg gcgggtgacc gccgggggcc cgcccccgcc gctccgcgag
    11881 tacctgcggc acggcgccgc gagcgtcgcg ctggccccgc tcgtcctcgc gatgtggtcg
    11941 ggcatggcct gcccggaacc ggtgctgcgc gcgctggaag ggccgctgcg ggacgcgtgc
    12001 ctggccgtcc ggctggccaa cgacctgagc gggcaccgcc gcgagcgggc cgagggcgtg
    12061 ctggacgcgc tctccctcgg catgagcccg ggcgaggcgc gggcccgctc cgccgagtgc
    12121 gtcgcgcgct gccgccgggc gctgcgtccg cacatcggcc cggtccccgg gccggcgctc
    12181 gccctggagc gccaactcct gtgggccgtg cgccactacg agcgggtcga cgccgggcac
    12241 gcggcatgac cggacggaac gtccgcgcct ccctgctcgc ccgcgcggag acgctgctcg
    12301 acggcctggg cgagggcggg tcgttcagcc cctgcccgta cacgacggct tggctgtcgc
    12361 ggctgcgcga ccgcgaccgg gtgctgttcc cgctcgcgcg ccgctggctc ctcgaccggc
    12421 agcgcgcgga cggctcgtgg ggcgccgtca tcggcctccc ccacgacagg accgtctgta
    12481 ccctcgccgc cgtcatggcc ctgaccgacc cggggccgcc cctgcccgga cgggccgagg
    12541 cggtccgcgc cgggctggcc tacctgcgcg cgcactccac ggcgtggcgg gccgccgacg
    12601 tcggggagac gatcgggttc gaactggccg tcccgttcct gctcggccag gcgtccgccc
    12661 gcggactgga cctgccctat ggcgactggg acgaactggc caagacccgc cgggcgaaac
    12721 tcgacctcat tccgagggac cgcctgctcc gcgagcccac gtcgctgatg tactccctcg
    12781 aagccgtcga ccccggtccc gcgctgcgcg ggctcgcgcg tttcgcgggc ccggacggct
    12841 cgctcgccaa ttccccctcc gcgacggcgg cgctctgggc ggccggcccg cacggcggga
    12901 tgccggcgta tttgaagaac gtggaaatgc cggacggcgg cgtcccgtcc ctctacccga
    12961 ccgaggcgtt cgagctggcc tgggcgctgc accatctcca gcgcggcggg ctcctcgata
    13021 tgcgggcgcc ttccgccgcc cgccgcgtcg cgcggctgcg ggccctcctc ggaccgcgcg
    13081 gccacctcgg gctcagcggc ggcttcccgc tgcccgaccc cgacgacacc gcgatggcga
    13141 tcatcgtgct gcacgcggcg ggccggggcg tcccgcacct gctggacgcc ctgctcgact
    13201 tcgagggcga gcactgcttc ttcacctatc cgggcgagcg cgacggatcg gtcaccccga
    13261 acgcccgcgt gctggaggcg ctcgcgctcc gtcccgccgc ctacacgcgt ccgatggcga
    13321 agatcgtcga gttcctcctg gacacccgcc gcgaggacgc ctggtggtac gacaaatggc
    13381 acgcgtcccc ctactacgcg accgcgcagg tgacgttcgc gctgacgcgg gcgtccaccc
    13441 tgccgctgga ggggaccctg gcctggctcc tcgccaccca gaggccggac gggtcgtggg
    13501 gctggtacgg gacgggcacg ccggaggaga cgggctgcgc cgtcctcaac ctggacgccc
    13561 tggcccgcca cggcatgcgc gtccccaggt cggcgtgggt cggcgcccac cgctacctgc
    13621 ggaaccacct cgacggcccg ttcccggaac tctgggtggg acgaagcctc tacacgccgc
    13681 gggacgtgtc gtcctcgacg gtgctggccg gggcggcgct ggccgccgcc cgcaccgcgc
    13741 ctagcggcgc gtagccgtcc gccgcgacac cagcatcggc aggcggtccg gacgcagcgc
    13801 gcccgcgacc cgctcccgga cctcggcccc gggcgcgggc gccaccgacc accgcgcgga
    13861 cacgctcgcg actatcacgc tcagctgtat gtaggagaaa tggtcgccga tacattttcg
    13921 gggccccgcg ccgaacggca cgaaatgctc cctcggcggc ggcgacagcc accggtcggg
    13981 atcgaaccgg agcggctccg gatagagaac agggtcccga tggaacgtcg tggggctgta
    14041 cagcaactcc gctcccgccg gaatgcgata tccgccgaga tcgacgtcga cgcgcgcgcg
    14101 gcgggacatc atccacgcga cgctgtgcag ccgcagcgtc tcgtcgatga gccgccgcgt
    14161 gtagcgcaga tgggggaggt cgtcgaactc gacggggcgt ccgcccagga cggcgtccag
    14221 ctcctcctgc aaccgggcct gcatctccgg gttccgcccc agctcgtggt acagccacga
    14281 cagggtggtc gggacggtct cggacccgcc cgcgaggatg gtcacgagct cgtccctgag
    14341 ctgcgcggcc gacatggcgg cgccggtgtc ctcgtcccgc gcgtccatca gcagcgacag
    14401 caggtcgtcc cgctccccgg gatcgcgccg ccgctcctcg accatgccgt ccacgatctc
    14461 ccggagccgc gcggcgaccc gcgcgaaccg ccggttgccg ggcagcggca gccgcgtggc
    14521 gaagcgcggc agcacggccc gcagcgggat ctcccgcagg aacaccgtga cgcagtggtc
    14581 gatctcggcg acggtggcct cgtccaggtc cgcgcggagc agcgcccgca gtgccccggc
    14641 cgcgctcgcc cggtgcagcg ccacgtccag ctcgacgcgc tgcccgtccc gccacgaccc
    14701 ggcgagcacc tccgcctgct cccgcaggac cccggtgtaa ccgagcagcc gcgcccggtg
    14761 gaaggacggc atcatcagcc gcctccggcg caggtgcgcg tccccgtccg cggtggccag
    14821 gccgcccccg agcaccggcc gcgcccggtc gtaggcccgc ccccggacga acgacccggc
    14881 gtcggtcacc agcatccgcc gcagcgggtc cggcgcgttc accagataga ccggcaccgt
    14941 cccgagccgc accaccacga ccggccccac ctcccgcaga tcctgcaaca gcccgacggg
    15001 atcccggacc agccgccgcg cgacggccga ccctccgggc ccccgcggaa caccgggccc
    15061 gtggcgaccg atgagaagcg gcatcgaacc tccatgaaga gcgaaggcga ggcgatcccc
    15121 tcgcccgccc aaccctccgg ccacgaccgc ccaccttcac ccagacgccc gaaccactac
    15181 ccgccgcaga gaggaagttg accaagcaaa gaacgatcta cgatccccgc cccactggga
    15241 gaccccacca accgaccctc ccaagcacgg ctctcgcgta agcccagcgc aggaggggtt
    15301 tgattgtgaa tcgagttaat gagtgctttc atggagtgca tgactcacca tgtgcttcgg
    15361 ttcgcggccg ggacgcacac cggacggcag cggacggtca acgaggactc ggcgttcgcc
    15421 tccccggggc tgctcgcggt cgccgacggg atgggcggcc acccgcacgg cgacgtcgcc
    15481 agccgcaccg cgatcaccgt cctcgccgag gccgccccgc accgcgcggc ggggcgcgaa
    15541 ggaggcgacc cggggcccgc gctcgcctcg gcggtcacgg acatcgccgc ccgcctggac
    15601 gacctcggac gccacgaccc ggacctcgcc cggatgggca cgaccttgac cgcgctggcc
    15661 tgggacggcg ccgggttcgc cgtcgcccat atcggcgact cgcgcgccta cgtcctgcgc
    15721 ggcggcgtgc tggagcggat cacgcgcgat cacacgatgg tccagatcct ggtggacgag
    15781 ggccggctca cccccgagca ggccgcccgg cacccgcgcg cctcggtgct ggtgcgcgcg
    15841 ttgcagagcg gcgcgcgggc tcagccggac ctctaccacc gggaggcgcg gccgggcgac
    15901 cggtacctcc tgtgttcgga cggcgtgtcc ggcgtcatcc ccgacgaggc gatccgggac
    15961 gcgctggacg ccccggcccc cgaggaggcc gtcgaccgcc tcgtcgccct cgccaacggc
    16021 gcgggcggcc ccgacaacat cacctgcgtc gtcgccgacg tcgtcccgga ggccgcagac
    16081 gccgatacac agtcgcccga actgctcggc gccgccgcgc acgcccccac ggggcctctg
    16141 gcgaggctcg gccgccgttt gcgccgggcg tgacgagcga agaagccgtt gacccggttc
    16201 gcgggtgtcg gtgttcagcc gcctgtgccc tcgatgtcgc cgcccgcgac ggacttcgcc
    16261 tcctgggctc ccggtccctg ccgggagttc gggttgtggc ctgtggagtg gttgttgaca
    16321 cgattcacgg gtgttctttc cgcgtattgg gcttccgtta gagttggggc atgagcgacg
    16381 accctggggt gaccgcaggc gacatcgccc gtatcgcggg tgtgggccgc gcgacggtca
    16441 gcaactggcg ccgccggcat gccgactttc cgcggcccgt cggcgggacg gccgccagcc
    16501 cgctgttctc gctcaccgac gtcgagggct ggctgatccg caacggcaag ccgttcgagg
    16561 tgtcgctcgg cgaccgggtc tggcagcggc tccgcgcgtc cgccgacgac ttccgcctcg
    16621 ccgacctcgt cgggtgggcc gggctgcgcc tgctgggcga ccgcggcgac gcgaccgggc
    16681 cgtcgcaacc agcgatcatc cccggcgacc ccgaactgcc cggcatgctg aaggacctcg
    16741 ccgccgagta cggccaccgg ggcgccttcg agctgatctt cgagcggtac gccgccgccc
    16801 actcgcggcg gctcgtcctc acccgcgggg acgtggcgcg gctgatgacc cggctcgcct
    16861 gccgggaggg cgacaccgtc ctcgacccgg cctgcggcct cggcaccctg ctcctcgccg
    16921 cgcccggcgc ggggcgcgtg ctcggccagg agagcgaccc ggccgccgcg cggatcgccc
    16981 tgctgcggct gctgctcgcc cggacgcctg ccgagatcgt cgccgccgac tccctgcgcg
    17041 cggacggctt cgccgaggag gccgccgact ccgccgtctg caacccgccg ttcggcgacc
    17101 gcgcctgggg ccacgaggac ctgaccggcg acccgcgctg ggagtacggc ctgccgccgc
    17161 gcggcgagcc cgaactcgcc tgggtgcagc actgcctcgc ccatgtgcgg cccggcggac
    17221 gcgcggcgct gctcatgccg tccgccgtcg cgagccgccg gcccggccgc cgcgtccgcg
    17281 gcaacctgct gcggaccggc gccctgcgcg ccgtcgcgac cctcgcgccc ggcggccccg
    17341 acctgtggct cctgcgccgt cccggaccgg gcgaacggcc ccccgaacgg atcctcctgc
    17401 tggacgccga gggcgacctc gaccgcgtcg aacgcgaatg gaaccggcac gtcgacggcg
    17461 gcggcgaatg gtcggtgccc gtcgtcgacc tcctggacga cgaggtcgac gtcaccccct
    17521 cccggcaccg cccccgccac agcggcccgg cgttcggccg ccgcttctcc gaggccctcg
    17581 accggctcgc cgccgccgct ccggagccgc cccgcgtcga cctcctgccc gaacagcggc
    17641 cgctgccgtt caccacgatc gccgaactcg ccagggccgg ggtcctcacc gtcatccacg
    17701 ccccggcgcg gccgctcacc ggcggcgccg tgccggtgct caccgtcgac gacctcacca
    17761 ccgggagcga cccctccggc gccgccgcgc ccgacccgtc cctgatcagg ctccagccgg
    17821 gggacgtcgt cgccaccgcc gccgggtccg cccgcgtcat cgccgagccc ggcgccgtcc
    17881 tcggccccca cctcacgctc taccgcccgg acggcgcgcg tctcgatccg catttcctcg
    17941 ccgggttcct gacgttcgcg cacacccgca ccggcaccgg ctccagccgc atggacctgc
    18001 gccggacgcg catccccagg ctctccctcg aaaggcagcg cgaatacggc cgggcgttcc
    18061 aggaactcgc ccggctgacc gcgacattgc gggagatgtc ggcccttggc gacgcgctgg
    18121 ttcggctgag cttcgacggg ctggtggacg gtcatctgcg tccccgccgt tgaccccggg
    18181 aggctcccgc gatgctcata gccgaccggt atgagctcga cgacctgccg ctcggacgcg
    18241 gcggaatggg cgccgtctac gccgccgacg acacccgcct cggccgccgc gtcgcggtga
    18301 agttcctcca actccccggc ggccccgacg acgagcttga gcggcgcttc atccgcgagg
    18361 cccgcatcct cgcccggctg gagcacgcgg gcgcccccac cctctacgac ttcggcacgt
    18421 tcgagcagcg gctctaccag gtcatgcagt tcatcgacgg cgtcaccgtc gccgacctca
    18481 tcgccgagca cggccccgtc cccgtcgcct gggccgccgg gatcaccgcg caggccgccg
    18541 ccgtcctggc agccgcgcac gccctgtcga tccgccaccg cgacctcaag ccgaccaacc
    18601 tcatgctctg ccccgacggc agcgtcaagg tcctcgactt cggcctcgcc gtcctcggcg
    18661 acgccgacgt cgcccacttc acccggcacg ggcagatcct cggcaccccg gcctacatgg
    18721 cccccgagca gatcgagcag ggcgtcgccg acccccgcag cgacctgtac gcgctcggat
    18781 gcgtcctgca cgagatgctg accggacggc agctgttcgc cgggcccacc gcctacgcgg
    18841 tgttcgacaa gcacgtccgg gaacagccgc cgcccatcca gggcatcccc tccgaactca
    18901 actacctcgt ccaggatctc ctggagaaga agccggagaa ccggccgccg gacgcgccgt
    18961 ccctctatga acgcgtccgt cccttcgcga ccgaccttcc gctcctgccc ggattcttgg
    19021 aacccgcgtc cacgtccagc cccgagcgga tgtacgcgct catcgtcggc caggccctgc
    19081 gaccccgctg acgcccgcgc atgacggacc ggccgggcgc gcccccgtcg tgcgcccggc
    19141 cggtccgcgt cctgtcagct ccgggccgcc gtgtgcgcga cgggccgctc gcccttcgcg
    19201 aggacggcgg gccgcggttg cgcggcggcc aggttcgcgg gccgcccgtg cccctcgtgc
    19261 gtgccgaccg gcgccttcac ctcgtgcatg gtcacctcgt gcacgggccg ggacacgccc
    19321 ctgggcggga cgggccggcg ctcacgcctc ccgggcgtcc ccgccccgga gccgtccagg
    19381 gccgccgcct cctgcgcgag ggcctgctcg ttcgcgtggt gcgcgttctc ggcctccgcc
    19441 accgcgccgt ccgcgacggc ggcggcatca tgcgagtgcg tggcggccgc atgcggcgcg
    19501 ctattcgcgt gcgccgcatt gtgcgcgtgg gccgtgttct ccggttgcgc ggcgccattg
    19561 ttgggcgccg ccccgtcctc ggtcgactcc gcgttctccg gttgggccgc gtcattggcg
    19621 ggcggtgccg ctgcgggtga cgcgtcgtcc gcttgattag ccggcgaccc cgcctcgatg
    19681 ggcggcgagt cctgagtcgg cgccgcctct tccgcggacg tttcctcgct cgtcggtgcc
    19741 gtttcgtccg cgggcgtcgg ctcgttcacg agcggcgcct gatgggtggc cggtgcgtcg
    19801 ttgtagggcg gtgtgggcca ttgggactgc gtggccgccg cctcgttggc gggcggcgcg
    19861 ggtttggccg gcgtggtgcg caggattatg ccgggcggca ggcccagagg cgaatccgcc
    19921 gtggtctccg gtgccttgtg ggccttctcc tgggcgctca tccggtcgat tttctcgacg
    19981 agttcacgga tggagggcga ccacttcttg tacgcgggcg cccccggacg gacggccccc
    20041 gcgaactgcc gtttgcgggc ggcgccgagt ctgtcgatcc ggacgcggga gcggctgttg
    20101 ggcgcgtgca ggaaccggcc gtggccgacg tagatgccga cgtggctgcg gccgtggaag
    20161 aagatcaggt cgccggggcg caggtccttg aaggcgacct tgcgccggac gccggagtac
    20221 tgcgagtagg tgacgcgcgg gatcttcacg cccgccctgc gccaggcggc catcgcgagg
    20281 cccgagcagt cgtagcgcgc gggaccggcg gcgccccagc tgtagggctt gccgatctgc
    20341 ttgcgggcga aggtcagcgc cttcctcgcc ttcgtcttct gcctggcctc acgggtgcgg
    20401 taccggtcgt aggccttgac cttgcccagc gtcaccgcgt ccaggtcgag ccttttcagg
    20461 acgaccgggt tgagcgccgc cagcgcctgc gtgcccgccg gaaggctgag cgcgagcccg
    20521 acggcggtca cggtggccgc gcgccggagc gtcctgcgtt ttcgctcggt cgtcccgccg
    20581 tggcggggtc ggccggggaa tgcccggggc cggtcgttcg gccggccgga ctggcgtgct
    20641 tcgcacattc gcgtgctccg ttttcgtgat gtcagatgat ctcctaccga cagttcgggt
    20701 acccgttgat cgcgggcgaa tggggagagt gcggggattt tacatgatca tgggtcggaa
    20761 ttggatccgg cgtttcgtgt ctttgatcat gtggtcagat gggccagcga gcggagcggt
    20821 accggcagcc acgcgggccg gttccgggcc tcgtagcgca cctcgtacac ggccttctcg
    20881 aactcgaagg cccgggtcag gacggcgtgg gcggccgggt cgacaccgcc cgcggcggcg
    20941 tagccgcggc agaacgcggc gcggttgcgc gcggcccacg cgtgcgcgcg ggtctccagg
    21001 cggcgcccgg actccggcgg cagggcgccc gccttggtga tcagaaagcg cgccgcgtac
    21061 tcgaaggagc gcagcatccc ggcgacgtcg cggagcgggt gggcgagggc gcggcgctcg
    21121 ccgggggtgc gggcgggttc gccctcgaag tccagcaccg tccagccgga ctcggtgcgc
    21181 aggacctggc cgaggtggta gtcgccgtgg acgcgctgga cgggcagcgg cgccgcccgc
    21241 gtcgcgaggt cgaggaacgc gccggtgagc gccttggcgt gcggggccag cgcggggacg
    21301 gcgcggcagg tctcggtgag gtcctcgttc atccgcgccg ccatcgcgtg gacctcgccg
    21361 gcgggcagcg tcgtcacgcc gaacgcgccc gcgagggcct ggtgcacccg cgcggtggcg
    21421 gcgccgagcc gctcggcctc ggccgcgaag tcgccgcccg cggcgctcgc gtccagctcc
    21481 gcccactcgt ccccgcccgg cggcatcgtg tgggcgtacc agtcgcggac gctggcgatc
    21541 gcgaggctcc agccgtccgc gccggtgcgc aggtaggtcg agagcagcgc gagcgtggtc
    21601 ggctcgccgc cttcgcccgg ctccagctcg atccacccga ggacggccgg gacgtgggcg
    21661 cagccgccgc gcgtcagcgc gaggttgacc tccaggtcgg ggttcacgcc gtcgctcagc
    21721 cgccggaaca gcttgcagat gtaggcgtcg ccgaacagca gcgaggtgtt gctctgctcg
    21781 gcggtgatcg gcaggctcgt caggtcggtg cggatcaccc cgccgcccgc gttccggaag
    21841 cgcagggggc cgacggacgc ctcggccgcc aggccgcgca gcagggtccg ggtcaggtcg
    21901 gggtcgtggg cggcgtcata gcagtgcgtc ccctcctcgg gggagccgcc gatctcggcg
    21961 tgcctgagcc ggtcgggcag gtcgcgccgg gtgccgagga ggagctggta ccggtcggtg
    22021 ccggtgtgct gccggacgtg gatgacgaga tggtgcagcg ccgggtcgcc ggaatggagt
    22081 tcggtggtcg cggcgatcgt gatgccgtcg atggggatgt gcttgccgcc gaaccagcgc
    22141 tgccggggca gccattcggc gaggtcccgc tggaggacgc tccgcggcgg cagcacggtc
    22201 aggcggtcct ctcggtgtcc gcgtcctccg gtggagtgag ctggaaccaa tggaaaccgt
    22261 gccccggcaa cgtcatgagg taggggagtt cgccgatcgc ggggaactgc accccgcccg
    22321 tgcattcgac gggggagtgg ccctcgaagc gccgcaggtc cagctcgacg ggctgcggga
    22381 agcgcgagag attgctgacg cagagaatga cgtccgttcc gccccactgg tccgcttcct
    22441 tttcccctat ctcgcgggtg aaggcgagga cggaggggtt ggaggcggag agttcgttgt
    22501 aggtgccgac gccgaagacg gggtggcgtt ggcggatttc gatcatggtg cgggtccagt
    22561 gcaggaggga tccgg
//
