LOCUS       NZ_WOFH01000002        23799 bp    DNA     linear   CON 29-SEP-2024
DEFINITION  Actinomadura litoris strain NEAU-AAG5 Scaffold2, whole genome
            shotgun sequence.
ACCESSION   NZ_WOFH01000002
VERSION     NZ_WOFH01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinomadura litoris
  ORGANISM  Actinomadura litoris
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1  (bases 1 to 842719)
  AUTHORS   Cao,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-NOV-2019) Northeast Agricultural University, College
            of Life Science, No. 600 Changjiang Road, Harbin, Hei Longjiang
            150030, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 109x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009733595.1-RS_2024_09_29
            Annotation Date                   :: 09/29/2024 03:46:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,194
            CDSs (total)                      :: 8,115
            Genes (coding)                    :: 8,044
            CDSs (with protein)               :: 8,044
            Genes (RNA)                       :: 79
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 1 (5S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 14 of 71
            Pseudo Genes (incomplete)         :: 60 of 71
            Pseudo Genes (internal stop)      :: 4 of 71
            Pseudo Genes (multiple problems)  :: 6 of 71
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:00:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 349879
            Orig. end                         :: 373678
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            WOFH01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23799
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..23799
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23799
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:13799](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13799
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    47..56
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     misc_feature    130..144
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.3"
                     /tool="antismash"
     gene            complement(471..1118)
                     /locus_tag="GNZ18_RS06090"
                     /old_locus_tag="GNZ18_06100"
     CDS             complement(471..1118)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) dTDP_sugar_isom"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017609337.1"
                     /locus_tag="GNZ18_RS06090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_06100"
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="WP_156215149.1"
                     /sec_met_domain="dTDP_sugar_isom (E-value: 1.4e-46,
                     bitscore: 153.7, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIEPMSVLDAYRITPTHHEDRRGSFYESWRFEELAAHLGHPFVV
                     RQANFSASRRNTLRGIHGTTSPPGQAKLVTCVRGAALDVVVDLRVGSPTFGRFDITPQE
                     ADSGVAVCLADGLGHGFLALTDDTCMNYLCDTEYIHGTMLDIQALDPELGIPWNLDGEP
                     IRSDKDTAAPTLAEAAAAGLLPRYRPGGTLPGEGEAHGGRTRPGPVRGDRLR"
     gene            complement(1118..2287)
                     /locus_tag="GNZ18_RS06095"
                     /old_locus_tag="GNZ18_06105"
     CDS             complement(1118..2287)
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037650.5"
                     /locus_tag="GNZ18_RS06095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_06105"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_156215151.1"
                     /transl_table=11
                     /translation="MQVTTEQAELLILAAGGREAELLAAIEDVGAKAVSSLAVEELVFR
                     CRLPSNKTHVHIQLDLLHGGERFTHTVGVRAGEPVTLHEGELDTAVYLLEFELAELVRG
                     LYGPLRERRAGTHRSRLLVERPTAKALYDGPLRGDWYSVGRAVDTVLSGCSAGPSDLGE
                     LSVRHGTDKWGTWHWYTPHYERHLRALRGEPVRLLEIGIGGYDDPDLGGWSLKMWKAYF
                     PRGLMTGLDVHAKHGLDEPRLRTVKGDQNDPDFLRAFGEEHGPFDVIVDDGSHVNEHIR
                     TSFEALFSYVRPGGFYIIEDIWTAYCAKFGGDEGPVSPPTTSIGMLQALLDKLHYQERA
                     GDEGDDIARSVVGVHVYHNIAFIEKGHNAEGGIAPAVGRLFESSPSTPR"
     gene            complement(2320..3558)
                     /locus_tag="GNZ18_RS06100"
                     /old_locus_tag="GNZ18_06110"
     CDS             complement(2320..3558)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF028221.5"
                     /locus_tag="GNZ18_RS06100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_06110"
                     /product="hypothetical protein"
                     /protein_id="WP_156215153.1"
                     /sec_met_domain="Condensation (E-value: 4.7e-07, bitscore:
                     24.6, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPADERVLTPRESMIVASGASPAFITVTAEGDLDAGALDRAMGLL
                     ARAHPILRTEIVRTGGERFVLRVAAGRPPLVLHEDGTTFTDVVTAPWRVGERAARLVVL
                     REGRRCTIVLAVHHAVADGRLITALLQRLVEHYDALVSGVPVPAADRDGLDPPLEEVLR
                     REGPPDPAPPPRPAPPPEVATLAPRTVQPNGPASFGFTNLRFDPEATARFVAAAKLHGL
                     SVSSLVAGAMATSLRTLHETGGPLTLALCLQVDLRARMSPPIPPEAAMSAVGSVIINLP
                     VAREATPVEVGLRVDGEMEAAADRALHQARLLAAGTLDLSGTQEISVSISNLGRLSFPA
                     TAGGLRFEAIRSVATMPFMRVPALVSNTVNGSLNLDLIYNRAFLADEPARHLTRELRNR
                     MAAPAGTGARSPV"
     gene            complement(3580..3810)
                     /locus_tag="GNZ18_RS06105"
                     /old_locus_tag="GNZ18_06115"
     CDS             complement(3580..3810)
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024851.5"
                     /locus_tag="GNZ18_RS06105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_06115"
                     /product="ferredoxin"
                     /protein_id="WP_156215155.1"
                     /transl_table=11
                     /translation="MDDEQWRVQVDRRTCIGSGLCTAIAEGHFTLDEGRSRPTAEVIAP
                     EDAVLDAAEFCPVEAILVRAAGTRTVLAPQP"
     gene            complement(3821..5026)
                     /locus_tag="GNZ18_RS06110"
                     /old_locus_tag="GNZ18_06120"
     CDS             complement(3821..5026)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546118.1"
                     /locus_tag="GNZ18_RS06110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_06120"
                     /product="cytochrome P450"
                     /protein_id="WP_156215157.1"
                     /sec_met_domain="p450 (E-value: 1.7e-18, bitscore: 62.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAESEVRDYPFIGEATGVEVDPLYAELRREEPVSRIRLPYGGEG
                     WLVTRYEDTKQVFADPRFSRAATVGREDVPRTTPEPAGGGFLLSMDPPEHSRVRRLVAK
                     AFTHRRVERLRPRVQEIVDARLTAIERSGPPADLVSRLALPLPITVICEMLGVPPQDQD
                     RFRDFSDAILSTTAYTRDEILAVRDALLTYLADMVRRRREHPADDLLGALVAARDDEDR
                     LSEEELVNLGVGLLIAGHGTTANQISNFTYVLLTRPGSWELLRDKPDLVPGAIEELLRY
                     VEFGTGGSFARIATEDVEVGGVLVRAGEAVFVNAQAANRDGTVFEDPDEVDLTRGRNPH
                     LTFGHGLHHCLGAQLARLILQVAIGSLLRRFPALRLAVPAEDVPWKTGLLVRGPNALPV
                     SW"
     misc_feature    5050..5065
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 24.14"
                     /tool="antismash"
     misc_feature    5051..5064
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.1"
                     /tool="antismash"
     gene            complement(5125..7596)
                     /locus_tag="GNZ18_RS06115"
                     /old_locus_tag="GNZ18_06125"
     CDS             complement(5125..7596)
                     /EC_number="2.1.-.-"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025033.5"
                     /locus_tag="GNZ18_RS06115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_06125"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_216651175.1"
                     /transl_table=11
                     /translation="MLASAVGALDAAGLLDGAPGGRGGLPDTGYLRALWRCLAAAGWID
                     PTPAWTERGRNALAHRARYVAGHRFLARFDDNAPDSWARPWDAPTGAAFAEALDAHEKW
                     RATADAGAPGTAHLDAALAVPAILTLRGTGRLHRPEGDFARLFRLLGWLDLDGAWTPRG
                     GAALDFADHCGLIGSYLPMLSRLEPLLRGELLVAPGDGEWHCQRRINVEASAAAHRRYF
                     ADADPVIEEVFRRRSRPVFVADMGCGDGSWLAHLHGLLGDGVRYVGVDVSPVALDRARA
                     VLRAAGVSDPLLLLGDVTDPDALAGMLARHGLAIEDGLHIRSFIDHDRTYVGGDPGGGA
                     PGWSSGAYVSPAGAPLSPAQVESDLVAHLRRWAPHVREHGLVVLEAHGVAPRLAARNPG
                     ALHSVALDTYHALSHQYLVEHSAFLHCCRLAGLEPVGHLERRYPSDRPFVAVSLNHLVP
                     ARPFPRHAPGERRDTWRPDPGTDLTDGRGLHDLLFTGGDLARPRGWCAGATGIVVRHVL
                     EAVEARVGRVGPGEAVRVLDYGAGTGLASIELVKACAERDVAGRLAERGASFELHLVDI
                     PGSWFAQGYALLRDLSWTRFHALRGADGRFRPLLDVTGGLRMDAVLANMVFHLLDGKAM
                     RKAAPSIAGVLRPGGVLAFSAPDLAAPTGSSLLFHDANRLMRRYWLAALDGARTDGLAP
                     VLREAAASAREVSRSSAQRRADRRILPTPRHIDAVAAELAPYFSGTAERRTYEILAEEC
                     LMTALVPANQQEFLAEIPDRDLREGVIRHLLLDRVLPELMDGPAGTARGLNLEWKLGRF
                     TRTARSTTTGE"
     gene            7931..9109
                     /locus_tag="GNZ18_RS06120"
                     /old_locus_tag="GNZ18_06130"
     CDS             7931..9109
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.5"
                     /locus_tag="GNZ18_RS06120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_06130"
                     /product="cytochrome P450"
                     /protein_id="WP_156215161.1"
                     /sec_met_domain="p450 (E-value: 1e-29, bitscore: 99.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTDHIIDYPSSADHAGELPPEFDAARGPGPLPRVRLPDGRTAWL
                     VTRHEDVRTVLAGGSFTRDLSEPRDGGGASPVRTVNMDGRPHLELRGLVSRAFTVRRVE
                     AMRPRVQEVTDRLLDAMEEQGPPADLVRHLAAPLPSIVICELLGFPHADHAMLGDWCDR
                     ITAVGGEGLDQSAGRELGAYIDRAVRARRAGADSGTDLLSTLVQAHDEEERLGHEELIS
                     LAIVLLAGGLETTQTAISAGLVRLLRNPEQLGRLRADPGLLGSTIEELLRFQPVIDLNR
                     VQKATEDVRLGGRLVRAGDLVQISINAANRDEDAFSCAARFEIAREPNPHLAFGHGAHH
                     CLGAALARAELRAAFATLLRRFPRLDLAEPPESLRWRGGHVTLRLEELPVTW"
     gene            9168..10004
                     /locus_tag="GNZ18_RS06125"
                     /old_locus_tag="GNZ18_06135"
     CDS             9168..10004
                     /EC_number="3.7.-.-"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013706.5"
                     /locus_tag="GNZ18_RS06125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_06135"
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="WP_156215163.1"
                     /transl_table=11
                     /translation="MLVCRYADGGRRGYGRVDHDHVVPVEYDPGAGRWVPRPGPARPLG
                     EVRVLAPAEPTKIVCVALNYRAEGAAGAGRPADSASMAVVLKPPSSLVGPWAPVSHPGR
                     SWVLKHEAELAVVIGTRCKRVSPGRAEAVVAGFTCANDITAYARDGAGPGGHPVWAKHF
                     DGCTPLGPWLATDLDAADAEITCRVDGELRQRGSTRDLLTPVHDVVALVSEHMTLLPGD
                     VILTGTPGGSGPLPVGGRVEVAIGGVGTLCNTIGEPSGAAGETGAAGSEREGRSTP"
     gene            10001..11035
                     /locus_tag="GNZ18_RS06130"
                     /old_locus_tag="GNZ18_06140"
     CDS             10001..11035
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.5"
                     /locus_tag="GNZ18_RS06130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_06140"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_156215165.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 6.1e-56, bitscore:
                     185.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAIDEGAHLRAADRPNPVGFLDGRDLLERDLLRLWQGRDGNLLD
                     RISHYALVPAGKMLRPLLVLESARCVGGRPEGLARPALALEYLHVSTLVHDDIIDEDDM
                     RRGRPSVQAAFGLASAIVAGDGLLLETFAALTDAPPEDVPAEAVVALVNTTAEAGLSVC
                     RGQLMETELVGDLDCGVERYLAMAGLKTGALFEASCRAGAILGGAPREWIDALGGFGSR
                     LGVAFQIRDDLLAFDGPLALIGKPQESDLHNHRPTLPILLAYQRASAADRERLERAFHE
                     DQPVEKSYAVVSEVLEATGARAAAGEVAAGLIRQAKDRLAALPAGESVLALAEIADYAA
                     RRRF"
     misc_feature    10028..10030
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11036..12061
                     /locus_tag="GNZ18_RS06135"
                     /old_locus_tag="GNZ18_06145"
     CDS             11036..12061
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ubiA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013226.5"
                     /locus_tag="GNZ18_RS06135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_06145"
                     /product="UbiA family prenyltransferase"
                     /protein_id="WP_156215167.1"
                     /sec_met_domain="ubiA (E-value: 3.7e-16, bitscore: 54.7,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGRRLGRTLTAHLRTWRPYTLWYVGLVGLAGATLTREITGGDRR
                     ETAGPVVAWLVPTLVWVAAHYLGDYLDRDLDAIDKPQRPIPSGRMRPATALACGAVLAA
                     GACAVALSVNWRTVLVLAGGIGGAVAYNGFFKARGLWGNLVRGALTGAALLFGAMTAAS
                     APPVELLPFVLVFAAHDAASNLVGTLRDVAGDREGGYATFAVRHGVRAGAWTAVALYGA
                     AVAAVLAGLPLLPGDRWAPLPVLLVAVALACHAFRMLFANGRVPPPRVALRSHGVLVVE
                     RLVLAGALLVPGLGLPAAVALLLPMLAVTLGTQRAMRSAHEFPSGGPEPTRGASELTGT
                     K"
     gene            12081..13799
                     /locus_tag="GNZ18_RS06140"
                     /old_locus_tag="GNZ18_06150"
     CDS             12081..13799
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024640.5"
                     /locus_tag="GNZ18_RS06140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_06150"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_216651176.1"
                     /sec_met_domain="T2TS (E-value: 1.7e-38, bitscore: 127.9,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRASLSSRVERSVARAAEALFAAQRPDGSWPNRRPTAVLGTAGAV
                     VALHLADPERSRDLVERGARWLVEAQNADGGWGGVARAPTQFVPTVVAASALHLLDPRG
                     AREPVRRARDLLDRRGGVRSLTDPGMAHMAATFLTLAGLGDIQGSRRIPLELLMLPRRF
                     WRPRLSFRVAPFVAMAFVQARHDPPKGLARLLHRLAVPAAYRALAEVERGENDRGGYGG
                     DNWLVSVVCIGLSRAGAPEELVSATVGYLRSNVHRDGSWHIMQGLDLIGGSYVARGLAD
                     AGFAADPRLARARAWLRGCQQDEAFPIFDAPPGGWGWEGPRGWPNILDSANVLSALVAA
                     GGEGDGEESLRRGLRWLESRQDRAGSWGTFVPDTTLANDGPCPYVTAQSVEVLLDGGVS
                     RQDPRIAKALEWLLAAQRADGAYEALWYRGLTPGTSMALVAFGRAGLTGHPAATRAREA
                     LLDAQLADGSWGPGETGVPGDDASAGTVEETAWALRGLLACGVPADDPRLRRAAEWIVA
                     AQRGDGLWEPSPVCMHIRDLAYYVDGLIVNGLALKALGSYRDAAAGSPLEEQGAP"
     gene            13796..15073
                     /locus_tag="GNZ18_RS06145"
                     /old_locus_tag="GNZ18_06155"
     CDS             13796..15073
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013646.5"
                     /locus_tag="GNZ18_RS06145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_06155"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_156215169.1"
                     /transl_table=11
                     /translation="MTARHPDADVVICGSGVAGLAAANALGGLGLEVILLDKKRSQPPI
                     AKGEVLQPGSLDILEGWDVLRVLEARGAARIDRLVAREPDGAELLAMDFGALGGARPWM
                     LSHYYTTILDCLGESLGRTVRWRRGVLVDDVVRDPAGRVTGVRTIEDGAAREIGARLVV
                     AADGMSSRLRRLSGITAEPLAYDHRLLTFELPCAPPVPDEVSAYVTGRGLVMVYALPDG
                     ATRLYVQVAADELRGMGADRLREWVAGLVGQVPALGPLAPAMLDGLDRRQLLKVWRYVV
                     PSLVRPGIALIGEAAHSVHPLAAQGMNTAIGDAHALAARLSGVDVEDGAAVDAALRGYE
                     DGRMRRIGDVHAMSHNAARMMTSTSRGGRLLGRRLLHSTARSARLRYLTTYNMSGLGMR
                     RLGTLDRLFQLGVLPDRRGAPSLAPE"
     gene            15113..15979
                     /locus_tag="GNZ18_RS06150"
                     /old_locus_tag="GNZ18_06160"
     CDS             15113..15979
                     /NRPS_PKS="Domain: TauD (10-251). E-value: 5.4e-64. Score:
                     208.4. Matches aSDomain:
                     nrpspksdomains_GNZ18_RS06150_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1121: dioxygenase, TauD/TfdA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014698.5"
                     /locus_tag="GNZ18_RS06150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_06160"
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_156215171.1"
                     /sec_met_domain="TauD (E-value: 6.6e-63, bitscore: 208.4,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAESATTAFDVRPLSGALGAEIHGVRLAEITDTEFAELRRLLLRY
                     LVVFIRDQHDWPPESRVAFGRRFGELEVHPYLPHLEGHPEIQIIDSEQDGKIPIWHTDM
                     TYSPNPPIGSVLQIVRSPGTGGDTMWSNQYLAYEALSAPLRGLLDGLTAIHAIHIPGLD
                     SRAEHPVVRVHPETGRRSLFVNRAHTSHIAQLSRNESDALLQFLYEFSTAPEFTCRHRW
                     RDGDVAIWDNRATQHYAVDDYAERRTGLRVVVLGDSPSGDPPRWDHFQPRPGERYAPFR
                     VNAKEPY"
     aSDomain        15143..15865
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GNZ18_RS06150_TauD.1"
                     /evalue="5.40E-64"
                     /label="GNZ18_RS06150_TauD.1"
                     /locus_tag="GNZ18_RS06150"
                     /protein_end="251"
                     /protein_start="10"
                     /score="208.4"
                     /tool="antismash"
                     /translation="VRPLSGALGAEIHGVRLAEITDTEFAELRRLLLRYLVVFIRDQHD
                     WPPESRVAFGRRFGELEVHPYLPHLEGHPEIQIIDSEQDGKIPIWHTDMTYSPNPPIGS
                     VLQIVRSPGTGGDTMWSNQYLAYEALSAPLRGLLDGLTAIHAIHIPGLDSRAEHPVVRV
                     HPETGRRSLFVNRAHTSHIAQLSRNESDALLQFLYEFSTAPEFTCRHRWRDGDVAIWDN
                     RATQHYAVDDYAERRTGLR"
     gene            15979..16728
                     /locus_tag="GNZ18_RS06155"
                     /old_locus_tag="GNZ18_06165"
     CDS             15979..16728
                     /GO_function="GO:0004833 - tryptophan 2,3-dioxygenase
                     activity [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /GO_process="GO:0019441 - tryptophan catabolic process to
                     kynurenine [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015272.5"
                     /locus_tag="GNZ18_RS06155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_06165"
                     /product="tryptophan 2,3-dioxygenase family protein"
                     /protein_id="WP_156215173.1"
                     /transl_table=11
                     /translation="MARAPAEPASPEPRYGDFLRLDTLLSLQRESEKAHDAHFFFTVHQ
                     VYELQFKIILYELDAAVAAVAADDVPRAVYCLRRVRAVEEILVAQVATLETISPGGFAV
                     LRGTLASSSGLQSVQFREIEFRSGLKDPGYLATTRMSGPERARLERRLSEPSLGDEFRW
                     LRLRRGDPDLVELYRAEVPGDGLVALAEAMIEHDEGFGLWRSRHVPMVERLIGRRRGTG
                     GSAGVDYLHATTAKRFYPELWELRARV"
     gene            16782..18380
                     /locus_tag="GNZ18_RS06160"
                     /old_locus_tag="GNZ18_06170"
     CDS             16782..18380
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trp_halogenase"
                     /gene_functions="biosynthetic-additional (halogenases)
                     flavin-dependent trp 6 7 halogenase"
                     /gene_functions="biosynthetic-additional (MITE)
                     MITE0000130: Halogenation (72% identity)"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1119: halogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF016693.5"
                     /locus_tag="GNZ18_RS06160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_06170"
                     /product="tryptophan halogenase family protein"
                     /protein_id="WP_312874325.1"
                     /sec_met_domain="Trp_halogenase (E-value: 1.2e-171,
                     bitscore: 567.0, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTLDNRIKKIVILGGGTAGWMAASYLGKALQGTVDITVLEAPSI
                     PRIGVGEATVPNLQRAFFDYLGIPEDEWMRECDAAFKIAVKFVNWRTPGEGQSTPRDLD
                     GRPDQFHHPFGLLPDEDQVPLSHYWFQRRHAGRTDEPFDYACMAEPAMMDAKRGPRWLD
                     GRRATRYAWHFDAQRVADFLCRFATKKQGVEHVQDTMEEALLDERGYITGLRTASGRVL
                     EGDLFVDCSGFRGLLINKAMGEPFVDMGDHLLCDRAVATAVPHDDASLGVEPYTSSIAM
                     SSGWTWKIPMLTRFGTGYVYSSQFTTQDEATEEFSRMWGLDPEKEDFNQVRFRVGRNRR
                     AWVRNCVSVGLASCFVEPLESTGIYFTYAALYWLAKLIPNGDFDPVLVDRFNREIQVMF
                     DDTRDFLQAHFYCSPRVDTEFWKANKELKLSDSIQEKMALYKAGLAINQPVTGESDYYG
                     NFEAEFRNFWTNGSYYCIFAGMGYLPDRPLPALAYKPESVRAAEPLFEEVKRRQREYAE
                     TLPSNYELLRAIHGR"
     misc_feature    16872..16874
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(18445..19257)
                     /locus_tag="GNZ18_RS06165"
                     /old_locus_tag="GNZ18_06175"
     CDS             complement(18445..19257)
                     /EC_number="3.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.5"
                     /locus_tag="GNZ18_RS06165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_06175"
                     /product="S9 family peptidase"
                     /protein_id="WP_216651177.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.4e-08, bitscore:
                     31.1, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_S9 (E-value: 7.9e-14, bitscore:
                     47.1, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTSDGGAPEPYPARLARLTSAPEGAYRTVPYGPSPEQFGEYWP
                     GGDGAAAVLIHGGYWRARYRLDLMRLMAADLNARGYAVWNIEYRRMDMPGGGRPGTFDD
                     VSAALDAMAGLGGGAVDPARVALVGHSAGGHLALWAAHRAAGPGRLSPAAVVSLAGVCD
                     LAAAARLGLSDDAVRTLLGGGPDEVPEVYRWADPAALAPIDVPQLVVHGTADEDVPIGL
                     SEAYAEAAGRAATLLTLPDTDHMDVITPGTAAWTRIAEELARLLPPRR"
     gene            complement(19254..20504)
                     /gene="kynU"
                     /locus_tag="GNZ18_RS06170"
                     /old_locus_tag="GNZ18_06180"
     CDS             complement(19254..20504)
                     /EC_number="3.7.1.3"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_function="GO:0030429 - kynureninase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006569 - tryptophan catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_5 (73-320). E-value: 3.5e-27.
                     Score: 87.2. Matches aSDomain:
                     nrpspksdomains_GNZ18_RS06170_Aminotran_5.1"
                     /codon_start=1
                     /gene="kynU"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR01814.1"
                     /locus_tag="GNZ18_RS06170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_06180"
                     /product="kynureninase"
                     /protein_id="WP_156215177.1"
                     /sec_met_domain="Aminotran_5 (E-value: 1.1e-22, bitscore:
                     76.0, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 2.8e-07,
                     bitscore: 25.6, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDPYVEEAGRLDAADSLAAFRDRFVIADPAIVYLDGNSLGRLPR
                     ATRDRLRAVADEWGEELIDGWRRWLPVGREAGDLVARIVGAEPGEVVLSDSTGVNLYKL
                     AVAALDARPGRDVIVTDDDNFPTDRYILDGVAAARGLKVRRIGPGLDDGVRPEDVEAAL
                     DARVALVCLSHVAYRSGAVADLAAVTAAAHRHGALVLWDLCHSAGAVPVGLSAAGADLA
                     VGCTYKYLNGGPGSPAFLYVRRDLQPRLEQPIWGWFGQSDQFAMGPDYRPVPAIERFLV
                     GTPPVLTGYAALEGARLTAEAGIEAVAAKARSLTGYALRLADAWLAPLGFRAASPRDGR
                     RRGAHLTLRHPSAWPVCQAAKAAGVVPDYRAPERLRLGFPPLYTRHIDVHEGLSRLREV
                     AASGRYRDFPDDPKGLT"
     aSDomain        complement(19545..20285)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GNZ18_RS06170_Aminotran_5.1"
                     /evalue="3.50E-27"
                     /label="GNZ18_RS06170_Aminotran_5.1"
                     /locus_tag="GNZ18_RS06170"
                     /protein_end="320"
                     /protein_start="73"
                     /score="87.2"
                     /tool="antismash"
                     /translation="REAGDLVARIVGAEPGEVVLSDSTGVNLYKLAVAALDARPGRDVI
                     VTDDDNFPTDRYILDGVAAARGLKVRRIGPGLDDGVRPEDVEAALDARVALVCLSHVAY
                     RSGAVADLAAVTAAAHRHGALVLWDLCHSAGAVPVGLSAAGADLAVGCTYKYLNGGPGS
                     PAFLYVRRDLQPRLEQPIWGWFGQSDQFAMGPDYRPVPAIERFLVGTPPVLTGYAALEG
                     ARLTAEAGIEAVAAKARSLTGYALR"
     misc_feature    complement(20469..20471)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    20555..20567
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 16.54"
                     /tool="antismash"
     misc_feature    20575..20589
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.0"
                     /tool="antismash"
     gene            20654..20914
                     /locus_tag="GNZ18_RS06175"
                     /old_locus_tag="GNZ18_06185"
     CDS             20654..20914
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039972.4"
                     /locus_tag="GNZ18_RS06175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_06185"
                     /product="DUF6059 family protein"
                     /protein_id="WP_156215179.1"
                     /transl_table=11
                     /translation="MDLRRMGRRLLHEFNYAMALNCMTMGFPFDMVLYLRQERDDFIGE
                     GRAEEAPPVQPPPDGHPERLVPYAALSPSEREFWSHLDHRT"
     misc_feature    20660..20662
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            21020..21781
                     /locus_tag="GNZ18_RS06180"
                     /old_locus_tag="GNZ18_06190"
     CDS             21020..21781
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019633205.1"
                     /locus_tag="GNZ18_RS06180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_06190"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_308166148.1"
                     /transl_table=11
                     /translation="MAEAFGSDPARYDRTRPSYPGALVDRIVAGRAGLDIVDVGCGTGI
                     SGRLFQAAGCAVLGVEPDARMAEFARSRGLEAEVAAFEDWEPSGRAFDAVVSGQSWHWL
                     DPAAGAAKAARVLRPGGRLAVFWNAETPPPDLLRAFGEVYRRVLPDSLVARQWTATAMD
                     GYAMLCAKAAGGMREAGAFGEPEEWRFAWEKTYTRDEWVDQLPTHGDHGQYPVAEVEEV
                     QAGIGAAVDAAGGAFTMRYTTIAMSAVRASA"
     gene            21821..23320
                     /locus_tag="GNZ18_RS06185"
                     /old_locus_tag="GNZ18_06195"
     CDS             21821..23320
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (8-390). E-value: 1.4e-85.
                     Score: 279.3. Matches aSDomain:
                     nrpspksdomains_GNZ18_RS06185_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012711.5"
                     /locus_tag="GNZ18_RS06185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GNZ18_06195"
                     /product="class I adenylate-forming enzyme family protein"
                     /protein_id="WP_216651178.1"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-91, bitscore:
                     303.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLSERGRQRHGERVAVVDGDRRVTYAELDRRTDGLAAAFDAMG
                     VGRGHRVAVLSHNRLEVLETYFALGKLGAAAVPVHYGAVPDEVAAIAGGCETSVIAGEE
                     ELLGRLAHPPGRAVLAFEGDRYREAAASGERPPPRDVPDDELMFILHTSATTGRPKGVC
                     VDHRSLRSVATGYLADVEPGRGVVFLQCGPLSHGAMVLPLAYMATGATVVLMRMFSPPE
                     CLATIRRTEATHLFLVPEMLRFILQAAKRSPVDLPSLREVIYAAAPMPRPLLLEAHAAL
                     GCGFRQVYGITEGGGPVATLAPSEHDYAPGEPAGAGASVGRAIMGTVVERRDGGELWVR
                     GPGRMRGYWNDPAATEEAVRDGWVRTGDLGTVDEHGYVHLAGRVKDVINRGGQKVFPAE
                     VERVLLGHPGVREACVVGVPSEEWGELPFAYVVAPDGADAAEEFVASLKDLVRERLARY
                     KRPVGFEVVGELPRNPAGKVTRRHLRTQAARRAAEPAGPRS"
     misc_feature    21830..21832
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        21845..22990
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GNZ18_RS06185_AMP-binding.1"
                     /evalue="1.40E-85"
                     /label="GNZ18_RS06185_AMP-binding.1"
                     /locus_tag="GNZ18_RS06185"
                     /protein_end="390"
                     /protein_start="8"
                     /score="279.3"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="RQRHGERVAVVDGDRRVTYAELDRRTDGLAAAFDAMGVGRGHRVA
                     VLSHNRLEVLETYFALGKLGAAAVPVHYGAVPDEVAAIAGGCETSVIAGEEELLGRLAH
                     PPGRAVLAFEGDRYREAAASGERPPPRDVPDDELMFILHTSATTGRPKGVCVDHRSLRS
                     VATGYLADVEPGRGVVFLQCGPLSHGAMVLPLAYMATGATVVLMRMFSPPECLATIRRT
                     EATHLFLVPEMLRFILQAAKRSPVDLPSLREVIYAAAPMPRPLLLEAHAALGCGFRQVY
                     GITEGGGPVATLAPSEHDYAPGEPAGAGASVGRAIMGTVVERRDGGELWVRGPGRMRGY
                     WNDPAATEEAVRDGWVRTGDLGTVDEHGYVHLAGRVKDVINR"
     CDS_motif       22262..22318
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GNZ18_RS06185_0001"
                     /evalue="1.20E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="GNZ18_RS06185"
                     /protein_end="166"
                     /protein_start="147"
                     /score="21.1"
                     /tool="antismash"
                     /translation="FILHTSATTGRPKGVCVDH"
     CDS_motif       22823..22894
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GNZ18_RS06185_0002"
                     /evalue="8.80E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="GNZ18_RS06185"
                     /protein_end="358"
                     /protein_start="334"
                     /score="30.9"
                     /tool="antismash"
                     /translation="GELWVRGPGRMRGYWNDPAATEEA"
ORIGIN
        1 cgtcgggccg gtagcggatg tcgccgcgcg gcttcggggg gatcgtgaag gcggccgcga
       61 gcgcccggac ctcgccgatc gccccgtccg cgaccagccc gtccacgcgg gcgtgctgcg
      121 ggtggtgcag gaacatcatg ttctccagca gcaggcgccc gcgctcgcgc gccagggcga
      181 tgagccgcgc ggtgtcccgt ccctcggtgg tgaacggctt ctcgacgagg acgtgcttgc
      241 ccgccagcag cgcccgctcg acccactcgg cgtgcagcgc ggccgggagc gggatgtaga
      301 cggcgtccac gtcgtcgcgt tcgagcagct ccgcgtagcc gcccagcgcg gcgccgatgc
      361 cgtgggcggc ggcggaccgc tcggccttcg cgaggtcgcg gctcgcgatg gcgcgcacct
      421 cgacgccggc gtccgcccgc atcgcgggca gggtccgccg cagcgcgatg tcagcgcagc
      481 cgatcacccc gaaccggacc gggccgcgtc cgtccgccat gagcctcccc ctctccgggt
      541 agggtgccgc ccggccggta gcggggcagc agtccggccg ccgccgcctc ggcgagcgtc
      601 ggcgccgccg tgtccttgtc cgaccggatc ggctcgccgt ccaggttcca cgggatgccg
      661 agctccgggt ccagcgcctg gatgtcgagc atcgtcccgt ggatgtactc ggtgtcgcac
      721 aggtagttca tgcaggtgtc gtcggtcagg gcgaggaacc cgtggccgag gccgtccgcc
      781 aggcagacgg cgacgccgga gtcggcctcc tgcggggtga tgtcgaaccg cccgaaggtc
      841 ggcgacccca cccgcaggtc caccacgacg tcgagcgcgg ccccccggac gcaggtcacc
      901 agcttcgcct gccccggcgg gctggtggtc ccgtggatgc cccgcagcgt gttgcgcctg
      961 gacgccgaga agttggcctg ccgcaccacg aacgggtggc cgaggtgggc ggccagctcc
     1021 tcgaaccgcc acgactcgta gaagctgccg cgccggtcct cgtggtgcgt cggggtgatg
     1081 cggtaggcgt ccaggacgga catcggctcg atcttcatca tcgcggcgtg gacggcgagg
     1141 actcgaagag ccgcccgacc gcgggcgcga tgccgccctc ggcgttgtgg cccttctcga
     1201 tgaacgcgat gttgtggtag acgtgcacgc ccaccacgct ccgggcgatg tcgtcgccct
     1261 cgtccccggc ccgctcctgg tagtgcagct tgtcgaggag cgcctggagc atcccgatcg
     1321 aggtggtcgg cggggagacg gggccctcgt cgccgccgaa cttcgcgcag taggcggtcc
     1381 agatgtcctc gatgatgtag aagccgcccg gccggacgta ggagaacagc gcctcgaacg
     1441 aggtgcggat gtgctcgttg acgtggctcc cgtcgtccac gatgacgtcg aacggcccgt
     1501 gctcctcgcc gaaggcccgc aggaagtccg ggtcgttctg gtcgcccttc acggtgcgca
     1561 gccggggctc gtccaggccg tgcttggcgt ggacgtccag cccggtcatg aggccgcgcg
     1621 ggaagtaggc cttccacatc ttcagcgacc agccgccgag gtccgggtcg tcgtacccgc
     1681 cgatcccgat ctccaggagc cgcaccggct cgccgcgcag ggcccgcagg tgccgctcgt
     1741 agtgcggggt gtaccagtgc caggtgcccc acttgtcggt gccgtgccgc accgacagct
     1801 cgccgaggtc ggacggcccg gcggagcagc cgctgagcac cgtgtcgacc gcgcgtccga
     1861 ccgagtacca gtccccgcgc agcggcccgt cgtacagcgc cttcgccgtg ggccgctcca
     1921 ccagcagcct gctgcggtgt gtgcccgcgc gacgctcccg cagcgggccg tacaggccgc
     1981 ggaccagctc cgccagctcg aactccagca ggtagacggc ggtgtccagc tcgccctcgt
     2041 gcagcgtgac cggctcaccg gcccgcacgc cgaccgtgtg ggtgaaccgc tcgccgccgt
     2101 ggagcaggtc gagctggatg tggacgtggg tcttgttcga cggcagccgg cagcggaaca
     2161 ccagctcttc cacggcgagg gagctgacgg ccttcgcccc gacgtcctcg atggcggcga
     2221 gcagctcggc ttcgcgtcca ccggcggcga gaatgagaag ttcggcctgt tccgttgtga
     2281 cttgcataga tgcctcccgg cggtagggaa ggggacggct cagacggggg agcgcgcgcc
     2341 cgtcccggcg ggagccgcca tgcggttccg gagctcccgg gtcaggtgcc gcgccggctc
     2401 gtcggccaga aacgcgcggt tgtagatgag gtccaggttc agcgagccgt tcacggtgtt
     2461 ggagaccagg gcggggacgc gcatgaaggg catggtggcg acggagcgga tcgcctcgaa
     2521 ccggaggccg cccgcggtcg cggggaagga cagccggccg aggttggaga tgctcaccga
     2581 gatctcctgg gtgccggaca ggtcgagggt cccggcggcg agcagccgcg cctggtggag
     2641 cgcgcggtcg gcggcggcct ccatctcgcc gtccacccgg aggcccacct cgaccggggt
     2701 cgcctcccgg gccaccggca ggttgatgat cacgctgccg accgcgctca tggccgcctc
     2761 cggcgggatc ggcggcgaca tgcgggcgcg caggtccacc tggaggcaca gcgccagcgt
     2821 cagcggcccc ccggtctcgt gcagggtccg cagcgaggtc gccatggcgc ccgcgaccag
     2881 gctgctgacc gacagcccgt gcagtttggc ggcggcgacg aaccgggccg tggcctccgg
     2941 gtcgaaccgc aggttggtga agccgaagct cgccggtccg ttcggctgga cggtgcgcgg
     3001 cgccagcgtg gccacctccg gcggcggcgc gggccgcggc gggggagcgg gatccggggg
     3061 gccctcgcgg cgcaggacct cttcgagcgg cgggtccagt ccgtcccggt cggcggcggg
     3121 caccgggacg ccggagacca gcgcgtcgta gtgctcgacg agccgctgga gaagcgcggt
     3181 gatcagccgt ccgtccgcga ccgcgtggtg gaccgccagg acgatcgtgc agcgccgccc
     3241 ctcacggagg acgacgagcc gcgccgcccg ctcgcccacc cgccagggcg cggtgaccac
     3301 gtcggtgaac gtcgtgccgt cctcgtggag cacgagcggc ggccgaccgg cggcgacgcg
     3361 gagcacgaac cgctcgccgc cggtccggac gatctccgtc cgcaggatcg gatgggcccg
     3421 cgcgagcagc cccatcgcgc ggtccagcgc gccggcgtcg agatcgccct cggccgtgac
     3481 cgtgatgaac gccgggctgg ccccggacgc cacgatcatc gactcccggg gggtgaggac
     3541 gcgttcgtca gcaggcatcg ggactccttt cctggcgcgt cacggctggg gggcgaggac
     3601 ggtccgggtg cccgccgcgc ggacgaggat cgcctcgacc gggcagaact cggcggcgtc
     3661 gaggacggcg tcctcggggg cgatgacctc ggccgtcggc cgggagcgcc cctcgtccag
     3721 tgtgaagtgc ccctcggcga tcgcggtgca cagccccgag ccgatgcacg tgcgccggtc
     3781 gacctgcacc cgccactgct cgtcgtccat ggccgccccc tcaccagctc accgggaggg
     3841 cgttcggccc gcgcaccagc aggccggtct tccacggcac gtcctcggcc gggaccgcca
     3901 gccgcagcgc cgggaagcgc cgcagcagcg agccgatcgc gacctggagg atcagccggg
     3961 ccagctgcgc gccgaggcag tggtgcaggc cgtgcccgaa cgtcaggtgc gggttgcgcc
     4021 cccgggtgag gtccacctcg tcggggtcct cgaagaccgt cccgtcccgg ttggctgcct
     4081 gggcgttgac gaacaccgcc tccccggccc gcaccaggac gccgccgacc tcgacgtcct
     4141 cggtggcgat ccgggcgaac gagccgcccg tgccgaactc gacgtagcgc agcagctcct
     4201 cgatcgcgcc gggcaccaga tcgggcttgt cgcgcagcag ctcccaactg cccggacggg
     4261 tgagcagcac ataggtgaag ttggagatct ggttggccgt cgtcccgtgg cccgcgatca
     4321 gcagcccgac gccgaggttg accagctcct cctcgctcag ccggtcctcg tcgtcgcggg
     4381 ccgccaccag cgcgccgagc aggtcgtcgg cggggtgttc gcggcgccgc cggaccatgt
     4441 cggcgaggta ggtcagcagg gcgtcgcgca cggcgaggat ctcgtcgcgc gtgtaggcgg
     4501 tggtggacag gatcgcgtcg gagaagtcgc ggaaccggtc ctggtcctga ggtgggacgc
     4561 cgagcatctc gcagatcacg gtgatcggca gcggcagcgc gaggcggctc accaggtcgg
     4621 cgggcgggcc ggagcgctcg atcgcggtca gccgcgcgtc cacgatctcc tggacgcgcg
     4681 gccgcagccg ctcgaccctg cggtgggtga acgccttggc gaccagcctg cgcaccctgc
     4741 tgtgctccgg cgggtccatg ctcagcagga agccgccgcc cgccggttcc ggcgtggtcc
     4801 tcggcacgtc ctcgcggccc acggtcgcgg cgcggctgaa cctcgggtcc gcgaacacct
     4861 gcttggtgtc ctcgtagcgg gtgacgagcc agccctcgcc gccgtagggc agccggatgc
     4921 gcgacaccgg ctcctcgcgg cgcagttcgg cgtagagcgg gtccacctcg acgccggtcg
     4981 cctcgccgat gaacggatag tcgcgcacct cggattctgc ggccatggaa ttctccttac
     5041 cgaggcccct caaatgcctg ttcgccttgg gagccactct gccggacgcc gatttcggca
     5101 acaatccgcg attagcgggg atggtcactc gccggtggtt gtgctacggg ccgtccgtgt
     5161 gaaccggccg agcttccatt ccaggttgag cccgcgcgcc gttccggcgg ggccgtccat
     5221 cagttcgggc agcacccggt cgagcaggag atggcggatc accccctcgc gcagatcccg
     5281 gtcggggatc tccgccagga actcctgctg gttggccggg acgagcgcgg tcatcaggca
     5341 ttcctcggcc aaaatctcgt aggtgcgccg ttcggcggtc ccggagaaat acggggccaa
     5401 ctcggcggcg accgcgtcga tgtgccgggg cgtcggcagg atgcggcggt ccgcgcgccg
     5461 ctgggcgctg gagcgcgaca cctcgcgggc gctcgccgcc gcctcccgca gcacgggggc
     5521 gaggccgtcc gtgcgcgcgc cgtcgagggc cgcgagccag taccggcgca tcaggcggtt
     5581 ggcgtcgtgg aacagcaggg agctgccggt cggcgcggcg aggtcgggcg cgctgaacgc
     5641 gagcacgccg cccggccgca gcaccccggc gatcgagggc gcggccttcc gcatcgcctt
     5701 gccgtcgagc aggtggaaga ccatgttcgc gagcacggcg tccatccgca ggccgccggt
     5761 gacgtcgagc agcgggcgga accggccgtc ggcgccgcgc agcgcgtgga accgcgtcca
     5821 ggagaggtcg cgcagcagcg cgtacccctg ggcgaaccag cttcccggga tgtcgacgag
     5881 atgcagctcg aacgaggcgc cgcgctcggc cagccggccc gcgacgtccc gctcggcgca
     5941 cgccttgacc agctcgatgg acgccaggcc ggtccccgcg ccgtagtcca gcacccggac
     6001 ggcctcgccc ggccccaccc gtccgacgcg ggcctccacg gcctccagca cgtgccgcac
     6061 gacgatcccg gtcgcccccg cgcaccagcc ccgggggcgg gccaggtcgc cgccggtgaa
     6121 cagcaggtcg tgcaggcccc ggccgtcggt caggtccgtg cccgggtccg gccgccaggt
     6181 gtcgcggcgc tcgcccggcg cgtgccgggg gaacggcctg gcgggcacca ggtggttgag
     6241 ggacaccgcg acgaaggggc ggtcgctcgg gtagcggcgc tccaggtggc ccacgggctc
     6301 caggcccgcc aggcggcagc agtgcaggaa cgcggagtgc tccacgaggt actggtggga
     6361 cagggcgtgg taggtgtcca gggccaccga gtgcagcgcc ccggggttgc gcgcggccag
     6421 ccggggcgcc acgccgtgcg cctccagcac caccaggccg tgctcgcgga cgtggggcgc
     6481 ccagcgccgg aggtgggcga cgaggtccga ctcgacctgc gcggggctca gcggcgcgcc
     6541 ggccggggag acgtaggcgc ccgaggacca gccgggcgcg ccgccgccgg ggtccccgcc
     6601 cacataggtg cggtcgtggt cgatgaacga ccggatgtgc agcccgtcct cgatggcgag
     6661 gccgtgccgg gcgagcatcc ccgccagcgc gtcggggtcg gtgacgtccc cgagcagcag
     6721 cagcgggtcg gacaccccgg ccgcccgcag cacggcgcgg gcgcggtcga gcgcgaccgg
     6781 gctgacgtcg acgccgacgt agcggacgcc gtcgccgagc aggccgtgca ggtgggccag
     6841 ccagctcccg tcgccgcacc ccatgtcggc gacgaacacg ggccgcgacc tgcgccggaa
     6901 gacctcctcg atgacggggt cggcgtcggc gaagtaccgc cggtgggccg ccgcgctcgc
     6961 ctcgacgttg atccggcgct ggcagtgcca ctcgccgtcc cccggggcga cgagcagctc
     7021 gccgcgcagc agcggttcca ggcggctcag catcggcagg taggagccga tgaggccgca
     7081 gtggtcggcg aagtcgaggg ccgcgccgcc ccgcggcgtc cacgcgccgt cgaggtcgag
     7141 ccagccgagc agccggaaga ggcgggcgaa gtccccctcg ggccggtgga ggcgtcccgt
     7201 cccgcgcagg gtcaggatcg cggggacggc gagggcggcg tcgaggtggg cggtgcccgg
     7261 cgcgcccgcg tcggcggtgg cgcgccactt ctcgtgcgcg tcgagcgcct cggcgaaggc
     7321 cgccccggtc ggggcgtccc agggccgggc ccaggagtcg ggcgcgttgt cgtcgaagcg
     7381 ggccaggaag cggtggccgg cgacatagcg cgcacggtgc gcgagcgcgt tccggccccg
     7441 ttcggtccag gcgggggtgg gatcgatcca accggcggcg gccaggcagc gccagagggc
     7501 gcgcaggtat ccggtgtcgg ggaggccgcc ccggccgccg ggcgcgccgt cgagcaagcc
     7561 ggccgcgtcc agtgccccga cggcggaagc cagcatcacc ccgtcctgga aaaggaatgc
     7621 ggtacggcgc gcctccgccc ggagggcgcg gtcgcctaag ccggccgggg cgacgactac
     7681 tgccggtggg tcatgtagca tcagaagatc tccaggatgg gttgattctg gcgctcgtcg
     7741 cgaaagcaac attgccagga gccgctcggg cgggccatta ccgattagcc ggggtggccg
     7801 ttccaaaaga cgcgtgttac gcttccgccg ctttattagc cctggccggc tagcacgcgt
     7861 tcccccggat gccaccccct ctttgtcggg gtggcccgtg cgcacggatc tgcggcactg
     7921 ttgcggaatc atgcctacgg atcacatcat cgactatccg agttccgccg atcacgcggg
     7981 cgagcttccc ccggagttcg acgcggcgcg cgggccgggg cccctgcccc gggtccgcct
     8041 gcccgacggc cggaccgcct ggctggtgac ccgccacgag gacgtccgca cggtgctcgc
     8101 gggcggctcc ttcacccgcg atctctcgga accgcgcgac ggcggcggcg cgagcccggt
     8161 gcggacggtg aacatggacg gccgcccgca cctggagctg cgcggcctgg tgtcgcgggc
     8221 gttcaccgtg cggcgggtcg aggcgatgcg cccgcgcgtc caggaggtga ccgaccggct
     8281 gctcgacgcc atggaggagc aggggccgcc cgccgacctg gtgcggcacc tcgccgcccc
     8341 gctgccgtcc atcgtcatct gcgagctgct cggcttcccc cacgccgacc acgcgatgct
     8401 cggcgactgg tgcgaccgca tcaccgccgt gggcggggaa gggctcgacc agtcggcggg
     8461 ccgcgagctg ggcgcctaca tcgaccgggc ggtccgggcg cggcgcgcgg gcgcggactc
     8521 gggcaccgac ctgctgagca cgctggtcca ggcccacgac gaggaggagc ggctcggcca
     8581 cgaggagctg atctcgctcg cgatcgtcct gctcgcgggc gggctggaga cgacccagac
     8641 cgcgatcagc gccgggctgg tcaggctcct ccggaacccc gaacagctcg ggaggctgcg
     8701 cgccgacccc ggcctgctcg gttcgacgat cgaggagctg ctccgcttcc agccggtcat
     8761 cgacctgaac cgggtccaga aggccaccga ggacgtgcgg ctgggcgggc ggctcgtgcg
     8821 cgcgggcgac ctcgtccaga tctccatcaa cgccgccaac cgcgacgagg acgccttttc
     8881 ctgcgccgcc cgcttcgaga tcgcgcggga gccgaacccg cacctggcgt tcggccacgg
     8941 cgcgcaccac tgcctcggcg ccgccctggc gcgggccgag ctgcgggccg cgttcgcgac
     9001 gctcctgcgc cgcttcccgc gcctggacct ggcggagccg ccggagagcc tgcgctggcg
     9061 cggcggccac gtgacgctgc gcctggagga gctgcccgtg acctggtgag acgcgtcccg
     9121 tccggtccgc ggggaagccg cggggaaccc gcagggaagg agcgcacatg ctcgtctgcc
     9181 gatacgccga cggcggccgg cgcggatacg ggcgcgtcga ccacgaccac gtcgtcccgg
     9241 tcgagtacga cccgggggcc ggacgctggg tgccgcgccc cggccccgcg cggcccctcg
     9301 gcgaggtgcg ggtgctggcc cccgccgaac ccaccaagat cgtttgtgtc gcgctcaact
     9361 accgggccga gggggcggcg ggggccgggc gtccggcgga ctccgcctcc atggccgtcg
     9421 tcctgaagcc gccgtcctcg ctcgtcgggc cctgggcccc cgtcagccat ccggggcgct
     9481 cctgggtgct caagcacgag gcggaactcg ccgtcgtgat cggaacgcgc tgcaagaggg
     9541 tctccccggg gcgggcggag gcggtcgtgg cgggcttcac ctgcgcgaac gacatcaccg
     9601 cctacgcccg tgacggcgcc gggccgggcg ggcacccggt gtgggccaag cacttcgacg
     9661 gctgcacccc gctcgggccc tggctggcga cggacctgga cgcggcggac gccgagatca
     9721 cctgccgcgt ggacggcgag ctgcgccagc gcggcagcac ccgcgacctc ctcaccccgg
     9781 tccacgacgt cgtcgccctg gtcagcgagc acatgacgct gctgcccggg gacgtgatcc
     9841 tcaccggcac cccgggaggc tccggcccgc tgcccgtcgg cggccgggtc gaggtggcga
     9901 tcgggggcgt cggcaccctg tgcaacacca tcggcgagcc gtccggcgcg gccggggaga
     9961 ccggcgccgc cggaagcgaa cgagaaggaa ggtccacacc atgagcgcga tcgacgaagg
    10021 cgcacactta cgcgcggccg accggccgaa cccggtcggg ttcctggacg gccgcgacct
    10081 cctggagcgc gacctgctcc ggctctggca gggccgcgac ggcaacctgc tggaccgcat
    10141 ctcgcactac gccctggtac cggcgggcaa gatgctccgc ccgctgctgg tgctggagtc
    10201 ggcgcgctgc gtcggcggcc gtcccgaggg cctcgcccgg ccggccctcg ccctggagta
    10261 cctgcacgtc tcgacgctgg tgcacgacga catcatcgac gaggacgaca tgcgccgggg
    10321 gcgtccctcc gtccaggcgg ccttcgggct cgcgtccgcc atcgtcgccg gggacgggct
    10381 gctgctggag accttcgcgg ccctcacgga cgcgccgccc gaggacgtcc cggcggaggc
    10441 cgtcgtcgcg ctcgtgaaca ccacggccga ggccgggctg agcgtgtgcc gagggcagct
    10501 catggagacc gagctggtcg gcgacctgga ctgcggggtc gagcggtacc tggccatggc
    10561 cgggctgaag acgggcgcgc tgttcgaggc gtcctgccgg gcgggggcga tcctcggcgg
    10621 cgccccgcgg gagtggatcg acgcgctggg ggggttcggg agccggctcg gagtcgcctt
    10681 ccagatccgg gacgacctgc tggccttcga cggcccgctc gcgctcatcg gcaagccgca
    10741 ggagagcgac ctgcacaacc accgccccac gctgccgatc ctgctggcct accagcgcgc
    10801 ctccgccgcc gaccgggagc ggctggaacg tgccttccac gaggaccagc cggtggagaa
    10861 gtcctacgcc gtcgtgagcg aggtgctgga ggcgacgggc gcgcgggcgg cggccgggga
    10921 ggtcgccgcc gggctgatcc gccaggccaa ggaccgcctc gcggcgctcc cggccgggga
    10981 gagcgtgctc gcgctggcgg agatcgcgga ctacgcggcc cggaggcggt tctgaatgcc
    11041 cggccgccgg ctcggcagga cgctcacggc ccacctgcgg acgtggcgcc cctacaccct
    11101 ctggtacgtc ggcctggtgg ggctggccgg cgcgacgctg acccgcgaga tcaccggcgg
    11161 cgaccggcgg gagacggcgg ggccggtcgt cgcgtggctg gtcccgaccc tggtctgggt
    11221 cgcggcgcac tacctgggcg actacctcga ccgcgacctc gacgcgatcg acaagccgca
    11281 gcggccgatc ccgtccgggc ggatgcggcc cgcgaccgcg ctcgcctgcg gggcggtcct
    11341 cgcggcgggg gcctgcgcgg tcgcgctgag cgtcaactgg cggacggtgc tggtcctggc
    11401 gggcggcatc ggcggcgcgg tcgcctacaa cggcttcttc aaggcgcggg ggctctgggg
    11461 caacctggtg cgcggcgcgc tcaccggcgc cgcgctcctg ttcggcgcga tgacggccgc
    11521 ctccgccccg ccggtcgagc tgctcccgtt cgtgctggtg ttcgcggcgc acgacgccgc
    11581 ctcgaacctg gtcgggacgc tgcgcgacgt cgccggggac cgcgagggcg gctacgccac
    11641 cttcgccgtc cggcacggcg tccgggcggg ggcgtggacc gccgtcgcgc tctacggcgc
    11701 ggccgtcgcg gcggtgctcg cggggctgcc gctcctgccg ggcgaccggt gggcgccgct
    11761 ccccgtgctc ctcgtcgcgg tggcgctcgc ctgccacgcg ttcaggatgc tcttcgccaa
    11821 cgggcgcgtc ccgccgccgc gcgtcgcgct gcgctcgcac ggggtgctgg tggtcgaacg
    11881 gctcgtgctc gcgggcgcgc tgctcgtgcc gggcctcggc ctgccggcgg cggtggcgct
    11941 cctgctgccg atgctcgccg tcaccctcgg cacccagcgt gcgatgcgct ccgcgcacga
    12001 gttcccctcc gggggccccg agcccacgcg cggcgcgtcc gaactgaccg gtacgaagtg
    12061 aggaaggcga ggacgccccc gtgcgcgcat ccctgagcag tcgagtcgag cgttcggtcg
    12121 cgcgggccgc cgaggccctg ttcgcggcgc agcgcccgga cgggtcgtgg ccgaaccggc
    12181 ggcccaccgc cgtgctgggc acggcgggcg cggtcgtcgc cctgcacctc gccgaccccg
    12241 agcgctcgcg cgacctggtc gagcgcggcg cccgctggct ggtggaggcc cagaacgccg
    12301 acggcggctg gggcggggtc gcgcgggccc ccacgcagtt cgtgccgacc gtggtcgcgg
    12361 cgtcggccct gcacctgctg gatccgcggg gggcgcggga accggtgcgg cgggcgcggg
    12421 acctgctgga ccggcgcggc ggcgtgcgct cgctcaccga ccccggcatg gcccacatgg
    12481 ccgcgacgtt cctcacgctc gcgggcctcg gggacatcca ggggtcgcgg cgcatcccgc
    12541 tcgaactgct catgctgccc cggcggttct ggcggccccg gctgtcgttc cgggtggcgc
    12601 cgttcgtggc gatggcgttc gtccaggccc gccacgaccc gccgaagggc ctcgcgcgcc
    12661 tgctgcaccg gctggccgtg cccgccgcgt accgcgcgct cgcggaggtg gagcgcggcg
    12721 agaacgaccg cggcggctac ggcggggaca actggctggt ctcggtggtg tgcatcggcc
    12781 tgagccgcgc cggcgccccg gaggagctgg tctccgcgac cgtcggctac ctccggtcga
    12841 acgtgcaccg ggacggctcc tggcacatca tgcaggggct cgacctgatc ggcggctcct
    12901 acgtcgcgcg cggcctggcc gacgccgggt tcgccgccga cccccggctg gcccgcgcgc
    12961 gggcgtggct gcgcggatgc cagcaggacg aggcgttccc gatcttcgac gcgccgcccg
    13021 gcggctgggg ctgggagggg ccccggggct ggccgaacat cctcgacagc gccaacgtgc
    13081 tgtccgccct cgtggcggcg ggcggggagg gtgacgggga ggagagcctg cggcgcgggc
    13141 tgcgctggct ggagtcgcgg caggaccgcg cgggctcgtg ggggaccttc gtccccgaca
    13201 cgacgctcgc gaacgacggc ccctgcccct atgtcaccgc gcagtccgtg gaggtgctcc
    13261 tcgacggcgg cgtgtcccga caggacccga ggatcgccaa ggcgctggaa tggctgctcg
    13321 ccgcccagcg cgccgacggc gcctacgagg cgctctggta ccgcggcctc accccgggga
    13381 cgtccatggc gctcgtcgcg ttcggccgcg ccgggctcac cggccacccg gccgcgacgc
    13441 gcgcccgcga ggccctgttg gacgcccagc tcgcggacgg gtcgtggggc cccggcgaga
    13501 ccggcgtccc cggcgacgac gcctcggcgg ggaccgtcga ggagaccgcg tgggccctgc
    13561 ggggcctgct cgcctgcggc gtcccggcgg acgacccccg gctccggcgc gcggccgagt
    13621 ggatcgtcgc cgcccagcgc ggcgacggcc tgtgggaacc gagcccggtc tgcatgcaca
    13681 tccgcgacct cgcctactac gtggacggtc tgatcgtgaa cggcctcgcc ctcaaggcgc
    13741 tcgggagcta ccgggacgcg gcggcgggca gcccgctcga agaacagggg gcgccatgac
    13801 ggcgcggcac ccggacgccg acgtcgtgat ctgcggatcg ggcgtcgcgg gcctggcggc
    13861 ggccaacgcg ctcggcgggc tcgggctgga ggtgatcctg ctcgacaaga agcgcagcca
    13921 gccgccgatc gcgaagggcg aggtgctcca gcccggctcg ctggacatcc tggagggctg
    13981 ggacgtgctg cgcgtcctgg aggccagggg ggcggcccgc atcgaccggc tcgtcgcccg
    14041 cgaaccggac ggcgccgaac tgctggccat ggacttcggg gcgctcggcg gcgcgcggcc
    14101 gtggatgctc tcccactact acacgacgat cctggactgc ctcggggagt cgctcggtcg
    14161 gacggtgcgg tggcggcgcg gcgtcctggt ggacgacgtc gtccgggacc ccgccgggcg
    14221 cgtcaccggg gtgcggacca tcgaggacgg cgccgcgcgg gagatcggcg cgcggctcgt
    14281 cgtggcggcg gacggcatgt cctcgcggct gcgcaggctg tcggggatca cggcggagcc
    14341 gctcgcctac gaccaccggc tgctgacctt cgagctgccg tgcgcgccgc cggtccccga
    14401 cgaggtgtcc gcctacgtga ccgggcgcgg actggtcatg gtctacgcgc tgcccgacgg
    14461 ggcgacgcgc ctctacgtcc aggtggcggc cgacgagctg cgcgggatgg gggccgaccg
    14521 gctgcgggag tgggtcgccg gtctcgtcgg ccaggtgccc gcgctcggcc cgctcgcgcc
    14581 cgcgatgctc gacggcctgg accgccgcca gctcctgaag gtctggcggt acgtggtgcc
    14641 gtcgctggtg cggccgggca tcgcgctgat cggcgaggcc gcgcacagcg tccacccgct
    14701 ggccgcgcag gggatgaaca ccgccatcgg cgacgcgcac gcgctcgccg cccggctctc
    14761 cggcgtcgac gtcgaggacg gcgcggcggt ggacgccgcg ctgcgcggct acgaggacgg
    14821 gcggatgcgc aggatcggcg acgtccacgc gatgagccac aacgccgcgc gcatgatgac
    14881 ctccacctcg cgcggcggcc ggctgctcgg ccggaggctg ctgcacagca cggcgaggag
    14941 cgcgcggctc cgctacctga cgacctacaa catgtcgggc ctcggcatgc gccggctcgg
    15001 gacgctggac cggctcttcc agctcggcgt cctgcccgac cgccggggag cgccctcgct
    15061 cgcgccggag tgaaccacgg atgcaccgac gacagaacgg aagtgttgcg agatggcgga
    15121 gtcagccacg acggcgttcg acgtccggcc gctgtcgggc gcgctgggcg ccgagatcca
    15181 cggcgtgcgg ctcgcggaga tcaccgatac ggagttcgcg gagctgcgcc gcctgctgct
    15241 gagatatctg gtggtcttca tccgggacca gcacgactgg ccgcccgagt cgcgcgtcgc
    15301 gttcggccgc cggttcgggg agctggaggt ccacccctac ctgccgcacc tggagggcca
    15361 cccggagatc cagatcatcg actccgagca ggacggcaag atccccatct ggcacaccga
    15421 catgacctac tcgccgaacc cgccgatcgg gtccgtcctg cagatcgtgc gcagccccgg
    15481 gacgggcggt gacacgatgt ggtcgaacca gtacctggcc tacgaggcgc tgtcggcgcc
    15541 gctgcgcggg ctgctcgacg gcctcaccgc gatccacgcc atccacatcc cggggctgga
    15601 cagcagggcg gagcaccccg tcgtccgcgt gcatccggag accggccggc ggtcgctgtt
    15661 cgtcaaccgg gcccacacct cgcacatcgc gcagctcagc cgcaacgaga gcgacgcgct
    15721 cctccagttc ctctacgagt tctccaccgc gccggagttc acctgccgcc accggtggcg
    15781 ggacggggac gtggcgatct gggacaaccg ggccacgcag cactacgccg tcgacgacta
    15841 cgccgagcgc cggacgggcc tgcgcgtcgt cgtcctcggc gacagcccga gcggcgaccc
    15901 gccccggtgg gaccacttcc agccccggcc gggcgagcgc tacgcgccct tccgcgtgaa
    15961 cgcgaaggag ccctactgat ggcgcgggcg ccggcggagc cggcgtcccc ggaaccccgc
    16021 tacggggact tcctgcggct ggacacgctg ctgtccctgc aacgggagtc ggagaaggcg
    16081 cacgacgcgc acttcttctt caccgtgcac caggtgtacg agctgcaatt caagatcatc
    16141 ctctatgagc tggacgcggc cgtcgcggcg gtggcggccg acgacgtccc gcgcgcggtg
    16201 tactgcctgc ggcgcgtccg cgcggtggag gagatcctcg tcgcgcaggt cgccacgctg
    16261 gagacgatca gcccgggggg cttcgcggtg ctgcgcggga cgctggcgag ctccagcggc
    16321 ctccagtcgg tccagttccg cgagatcgag ttccgctccg ggctgaagga ccccggctac
    16381 ctggccacga cccgcatgtc ggggcccgag cgggcccggc tggaacgccg gctgagcgag
    16441 ccgtccctgg gggacgagtt ccggtggctg cgcctgcggc ggggcgatcc cgacctggtg
    16501 gagctgtacc gcgcggaggt gcccggcgac gggctggtcg cgctggccga ggcgatgatc
    16561 gagcacgacg agggcttcgg gctctggcgg tcccggcacg tccccatggt ggagcgcctc
    16621 atcgggcggc ggcgcggcac cggcggctcc gccggggtgg actatctgca cgccaccacc
    16681 gccaagcgct tctaccccga gctgtgggaa ctgcgggcgc gggtatgacc cggcgcttca
    16741 ccgatccgcc gaagagagaa cacggagaag ggcagagaac tgtgagaacc ctggacaacc
    16801 gcatcaagaa aatcgtcatt ctcggcggcg ggacggcggg ttggatggcc gcgtcctatc
    16861 tgggcaaggc attacaggga accgtggaca tcacggtcct ggaggcgccg tccattccgc
    16921 gcatcggcgt cggcgaggcg accgtcccga acctccagcg ggcgttcttc gactacctcg
    16981 gcatccccga ggacgagtgg atgcgcgaat gcgacgccgc cttcaagatc gcggtgaagt
    17041 tcgtcaactg gcgcaccccc ggcgagggcc agagcacccc gcgcgacctc gacggccgcc
    17101 ccgaccagtt ccaccacccg ttcggcctgc tgcccgacga ggaccaggtc ccgctgtcgc
    17161 actactggtt ccagcgccgc cacgccgggc ggaccgacga gcccttcgac tacgcctgca
    17221 tggcggaacc ggccatgatg gacgccaagc gcggcccccg gtggctggac ggccgccgcg
    17281 ccacccggta cgcgtggcac ttcgacgccc agcgcgtcgc cgacttcctc tgccgcttcg
    17341 ccaccaagaa gcagggcgtc gagcacgtcc aggacacgat ggaggaggcg ctgctggacg
    17401 agcgcggcta catcaccggc ctgcgcaccg cgagcggcag ggtcctggag ggcgacctgt
    17461 tcgtggactg ctcggggttc cgcgggctgc tcatcaacaa ggccatgggc gagccgttcg
    17521 tggacatggg cgaccacctg ctgtgcgacc gggcggtggc cacggcggtc ccgcacgacg
    17581 acgcgagcct cggggtcgag ccgtacacct cgtccatcgc gatgagctcc ggctggacct
    17641 ggaagatccc gatgctgacc cggttcggga ccggctatgt gtactccagc cagttcacca
    17701 cccaggacga ggcgaccgag gagttcagcc ggatgtgggg cctggacccc gagaaggagg
    17761 acttcaacca ggtccggttc cgcgtcggcc gcaaccgccg cgcgtgggtg cggaactgcg
    17821 tcagcgtcgg gctcgcctcc tgcttcgtcg agccgctgga gtccaccggc atctacttca
    17881 cctacgccgc gctgtactgg ctggccaagc tcatcccgaa cggcgacttc gaccccgtcc
    17941 tggtggaccg cttcaaccgc gagatccagg tgatgttcga cgacacgcgc gacttcctcc
    18001 aggcccactt ctactgctcg ccgcgcgtcg acaccgagtt ctggaaggcc aacaaggagc
    18061 tgaagctgtc cgactccatc caggagaaga tggcgctcta caaggccggg ctcgcgatca
    18121 accagccggt cacgggcgag agcgactact acggcaactt cgaggcggag ttccgcaact
    18181 tctggaccaa cggaagctac tactgcatct tcgccgggat gggctacttg cccgaccggc
    18241 cgctcccggc gctggcctac aagcccgagt cggtgcgcgc ggccgagccg ctgttcgagg
    18301 aggtcaagcg ccgccagcgg gagtacgccg agacgctgcc cagcaactac gagctgctgc
    18361 gggccatcca cggccgctga cgcggcgccg gttcctcgga cgggtgcggc ggacccgtcc
    18421 ggggagccgg ccgggcgcga gcgcctaccg gcggggcggc aggagccggg ccagctcctc
    18481 ggcgatccgc gtccaggccg ccgtgcccgg ggtgatcacg tccatgtggt cggtgtccgg
    18541 cagggtgagc agcgtcgccg cgcggcccgc cgcctcggcg tacgcctcgc tcagcccgat
    18601 cggcacgtcc tcgtcggcgg tgccgtgcac caccagctgc ggcacgtcga tcggggccag
    18661 cgccgccggg tcggcccacc ggtagacctc gggcacctcg tccgggccgc cgccgagcag
    18721 cgtgcgcacc gcgtcgtcgc tcagccccag ccgcgcggcc gccgccaggt cgcacacgcc
    18781 cgcgagcgag acgaccgcgg cgggggagag gcgtcccggc ccggccgccc ggtgcgccgc
    18841 ccacagcgcc agatgccccc cggccgagtg gccgaccagg gccacgcggg cgggatcgac
    18901 cgccccgccg ccgagaccgg ccatcgcgtc cagcgcggcg gagacgtcgt cgaaggtgcc
    18961 gggccggccg ccgcccggca tgtccatccg ccggtactcg atgttccata cggcgtagcc
    19021 gcgggcgttg aggtcggcgg ccatcaggcg catcaggtcg agccggtagc gcgcgcgcca
    19081 gtagccgccg tggatcagga ccgcggccgc cccgtcgccc ccgggccagt actcgccgaa
    19141 ctgctccggc gagggcccgt acgggacggt ccggtacgcg ccctccggcg cgctcgtcag
    19201 ccgggccagc cgggcggggt agggctccgg cgctccgccg tcgctcgtgg tcgtcacgtc
    19261 agccccttcg gatcgtccgg gaagtcccgg taccggccgg acgccgcgac ctcgcgcagc
    19321 cgcgacagcc cctcgtgcac gtcgatgtgg cgggtgtaca acggcgggaa gccgagtctg
    19381 agccgctcgg gtgcacgata gtccgggacc accccggccg ccttcgccgc ctggcacacc
    19441 ggccaggcgg acgggtggcg cagggtgagg tgggcgccgc ggcgccgccc gtcgcggggc
    19501 gaggccgccc ggaacccgag cggcgccagc cacgcgtcgg ccagccgcag cgcgtacccg
    19561 gtcaggctcc gcgccttggc ggcgacggcc tcgatcccgg cctcggcggt caggcgcgcc
    19621 ccctccagcg ccgcgtaccc ggtcagcacc gggggagtgc cgacgaggaa gcgctcgatc
    19681 gcgggcaccg ggcggtagtc cgggcccatc gcgaactggt cgctctgccc gaaccagccc
    19741 cagatcggct gctccagccg cggctggagg tcccgccgca cgtacaggaa cgcgggcgag
    19801 cccggaccgc cgttcaggta cttgtaggtg cagccgaccg cgaggtccgc gccggcggcg
    19861 gacaggccga ccgggacggc cccggcggag tggcacaggt cccacagcac cagcgcgccg
    19921 tgccggtgcg ccgccgccgt cacggcggcc aggtcggcca ccgcgccgga gcggtaggcc
    19981 acgtgggaca ggcacaccag cgcgacccgg gcgtccagcg cggcctccac gtcctccggc
    20041 cgcacgccgt cgtcgaggcc ggggccgatc cgccgcacct tgagcccgcg cgccgccgcg
    20101 acgccgtcca ggatgtaccg gtcggtgggg aagttgtcgt cgtcggtgac gatcacgtcg
    20161 cgtcccggcc gggcgtccag cgccgcgacg gccagcttgt acaggttgac gccggtcgag
    20221 tcggacagca cgacctcgcc cggctccgcg ccgacgatcc gcgcgacgag gtcgcccgcc
    20281 tcgcggccga ccggcagcca ccgccgccag ccgtcgatca gctcctcgcc ccactcgtcg
    20341 gcgaccgcgc gcagccggtc gcgggtggcg cgcggcagcc ggcccagcga gttgccgtcc
    20401 agatagacaa tggcgggatc ggcgatgacg aacctgtccc ggaaagcggc cagcgaatcg
    20461 gccgcgtcta atcgcccggc ctcttccaca tacggatcgg tcatcgcctc acaatacggc
    20521 ccgccgtgcg cacgcaaaac ccctagcgcg tggaacgcga tttggaaagc cctcactctt
    20581 cagggtattc gcggccgccg ccgtcgggca acgtggctga ttggtggaat cgcaggacga
    20641 acggagagtc gcgatggact tacgcaggat gggacgccgg ctgctgcatg agttcaacta
    20701 cgcgatggcg ctgaactgca tgacgatggg ctttcctttc gacatggtgc tctatctgcg
    20761 ccaggagcgg gacgacttca tcggcgaggg ccgggcggag gaggcgccgc cggtccagcc
    20821 gcctccggac ggccatcccg agcgcctcgt tccctacgcc gcgctgagtc cttcggaacg
    20881 cgagttctgg tcccatctgg accaccggac gtgaactcca ttgacgagtg ggcagtcgcc
    20941 catttagagt gggcatatgc ccactaatcc ttccgcacgc gtcccgctct ccgagaaaga
    21001 gctccatcga cacaggcagg tggccgaggc gttcgggtcg gaccccgcgc gctacgaccg
    21061 cacccggccc agctaccccg gggccctggt ggaccggatc gtcgcgggcc gcgccgggct
    21121 cgacatcgtc gacgtcggct gcggcaccgg catctccggc cgcctcttcc aggcggccgg
    21181 gtgcgcggtg ctcggggtcg agccggacgc gcggatggcg gagttcgccc ggagccgcgg
    21241 gctggaggcc gaggtggcgg cgttcgagga ctgggagccg tccggccggg ccttcgacgc
    21301 ggtcgtctcc ggccagagct ggcactggct cgacccggcc gccggggcgg cgaaggccgc
    21361 gcgggtgctg cggcccggcg ggcggctggc ggtgttctgg aacgccgaga cgccgccgcc
    21421 cgacctgctg cgggccttcg gcgaggtcta ccggcgggtg ctgcccgact cgctcgtcgc
    21481 ccgccagtgg acggcgacgg ccatggacgg ctacgcgatg ctgtgcgcca aggccgccgg
    21541 cgggatgcgg gaggccggcg cgttcggcga gccggaggag tggcggttcg cgtgggagaa
    21601 gacctacacc cgcgacgagt gggtggacca gctgccgacc cacggcgacc acggccagta
    21661 cccggtggcc gaggtggagg aggtgcaggc ggggatcggc gcggccgtcg acgcggcggg
    21721 cggcgccttc accatgcgct acaccacgat cgcgatgagc gcggtgcggg cgtccgcctg
    21781 acggcccggc accaggaggg agaccaccac gatggcctgg atggcgcagt tatcggagcg
    21841 gggccggcag cgccacggtg agcgcgtcgc ggtcgtcgac ggcgaccggc gcgtcaccta
    21901 cgcggagctg gaccgccgga ccgacggcct ggccgccgcg ttcgacgcga tgggcgtcgg
    21961 acgcggccac cgggtcgcgg tcctctcgca caaccgcctt gaggtgctgg agacctactt
    22021 cgcgctcggc aagctcgggg cggcggcggt ccccgtccac tacggcgcgg tgccggacga
    22081 ggtggccgcg atcgccggcg ggtgcgagac ctcggtcatc gcgggcgagg aggagctgct
    22141 gggaaggctc gcccacccgc ccggccgcgc cgtgctcgcg ttcgagggcg accggtaccg
    22201 ggaggccgcc gcgagcgggg agcggccgcc cccgcgcgac gtccccgacg acgagctgat
    22261 gttcatcctg cacacctcgg cgacgacggg ccgcccgaag ggcgtctgcg tcgaccaccg
    22321 gtcgctgcgg tcggtggcga cggggtacct ggccgacgtc gaacccggcc gcggcgtcgt
    22381 gttcctccag tgcggccccc tgtcgcacgg ggcgatggtg ctgccgctcg cctacatggc
    22441 gaccggcgcg accgtcgtcc tcatgcgcat gttcagcccg cccgaatgcc tcgccacgat
    22501 ccgccggacg gaggcgacgc acctgttcct ggtgccggag atgctgcggt tcatcctgca
    22561 ggcggcgaag cgctcgccgg tggacctgcc cagcctgcgg gaggtcatct acgcggcggc
    22621 gccgatgccg cgcccgctgc tcctggaggc gcacgcggcg ctcggatgcg ggttccgcca
    22681 ggtctacggc atcaccgagg gcgggggacc ggtggcgacc ctcgccccgt ccgagcacga
    22741 ctacgcgccg ggagagcccg cgggcgcggg cgcctcggtc ggccgggcga tcatgggcac
    22801 ggtcgtggag cgccgcgacg gcggcgagct gtgggtgcgc ggcccgggcc ggatgcgcgg
    22861 gtactggaac gaccccgccg ccaccgagga ggccgtgcgc gacggctggg tgcgcacggg
    22921 cgacctcggc acggtggacg agcacggcta cgtccacctc gccgggcggg tgaaggacgt
    22981 gatcaaccgc ggcgggcaga aggtcttccc ggcggaggtc gagcgcgtgc tgctcggcca
    23041 ccccggggtg cgcgaggcgt gcgtcgtcgg cgtcccgagc gaggagtggg gcgagctgcc
    23101 gttcgcctac gtcgtcgccc ccgacggcgc cgatgccgcc gaggagttcg tcgcctcgct
    23161 caaggacctg gtccgcgagc ggctcgcccg gtacaagcgc ccggtcggat tcgaggtcgt
    23221 cggggagctg cctcgcaacc ccgcgggcaa ggtgacccgg cggcaccttc gcacgcaagc
    23281 ggcgcgccgc gccgccgagc ccgccggccc ccgctcgtga caggaggatc catgagcacg
    23341 aaaggcgccg aactcgacca cgtcctcgac cgccttcgag cgctgctgcg ggaggtctgg
    23401 gacgagcatc ccgccgacct cccggtggac ggcgacgcga cgctgctgag cctcggcgtc
    23461 gactcgctga cgctggtgtc gctgctcgac cgggtggagg cggagttcca caccgcgtgg
    23521 gaccccgacg acccgcccgg cgcctacagc tcgctgcgct ccatcgcggt cgcggcctcg
    23581 cccgccgcac cgcccgcggc accgcccgcc atgccgccca ccgggccgcc gctcgcgtcc
    23641 gggctcgccg cgtccgggct cgccgcgtcc gggcgccgcc atgtcgcggt cgaggactac
    23701 cggtcgctga tgagctcgtt cccgaccggc gtcgcggtcg tgaccggcgt cggcgcggac
    23761 atgctgccgc gcggcgccac ctgctccgcg ctgtgcagc
//
