LOCUS       NZ_CP040438            22898 bp    DNA     circular CON 07-MAY-2024
DEFINITION  Stenotrophomonas maltophilia strain PEG-173 chromosome, complete
            genome.
ACCESSION   NZ_CP040438
VERSION     NZ_CP040438.1
KEYWORDS    RefSeq.
SOURCE      Stenotrophomonas maltophilia
  ORGANISM  Stenotrophomonas maltophilia
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Stenotrophomonas; Stenotrophomonas maltophilia
            group.
REFERENCE   1  (bases 1 to 4769515)
  AUTHORS   Gonzaga,A. and Nubel,U.
  TITLE     Stenotrophomonas maltophilia genomes
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4769515)
  AUTHORS   Gonzaga,A. and Nubel,U.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-MAY-2019) Mikrobielle Genomforschung, Leibniz-Institut
            DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH,
            Inhoffenstrasse 7 B, Braunschweig 38124, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. v3.12.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150X
            Sequencing Technology             :: PacBIO + Illumina Miseq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009676565.1-RS_2024_05_06
            Annotation Date                   :: 05/06/2024 04:36:42
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,334
            CDSs (total)                      :: 4,244
            Genes (coding)                    :: 4,202
            CDSs (with protein)               :: 4,202
            Genes (RNA)                       :: 90
            rRNAs                             :: 5, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 22 of 42
            Pseudo Genes (incomplete)         :: 23 of 42
            Pseudo Genes (internal stop)      :: 2 of 42
            Pseudo Genes (multiple problems)  :: 5 of 42
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:36:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1787614
            Orig. end                         :: 1810512
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP040438.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22898
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="3"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22898
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22898
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12898](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12898
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            109..624
                     /locus_tag="FEO89_RS08295"
                     /old_locus_tag="FEO89_08380"
     CDS             109..624
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646745.1"
                     /locus_tag="FEO89_RS08295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO89_08380"
                     /product="hypothetical protein"
                     /protein_id="WP_049410369.1"
                     /transl_table=11
                     /translation="MRQSVSTVRVLSYALLAVAVAAGTTGCFKRGVKGDYALAPEMRPL
                     EVPPDLNLPTTTGDNKVPTLASATKPAAPVAAAPAVGNTGFTIAGGKDEAFAKVGTALE
                     GVEGVTIASRAQLLGSYDVAYEGSNFLVRVVAVDAGAYISAVDPRGLPATAEAPVKLIA
                     ALKAKLAQ"
     gene            complement(776..1099)
                     /gene="fdxA"
                     /locus_tag="FEO89_RS08300"
                     /old_locus_tag="FEO89_08385"
     CDS             complement(776..1099)
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /function="Ferredoxin"
                     /gene="fdxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005994928.1"
                     /locus_tag="FEO89_RS08300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO89_08385"
                     /product="ferredoxin FdxA"
                     /protein_id="WP_004153066.1"
                     /transl_table=11
                     /translation="MPFVVTENCIKCKHTDCVEVCPVDCFHEGPNFLVIDPDECIDCTL
                     CEPECPVNAIFPEDDVPAGQESFVALNAELAKEWPVLTVRKDPPADAGEWDGKPDKLKL
                     LER"
     CDS             1109..1294
                     /gene="allorf_1788723_1788908"
                     /locus_tag="allorf_1788723_1788908"
                     /protein_id="allorf_1788723_1788908"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MDRFLNPPILEQVGPRCRRGAENGRLAGSAAPPLATGRGLCDAAG
                     ARSPQVAAFPSQQDRP"
     CDS_motif       1109..1195
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MDRFLNPPILEQVGPRCRRGAENGRLAGS"
                     /locus_tag="allorf_1788723_1788908_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       1196..1294
                     /prepeptide="core"
                     /locus_tag="allorf_1788723_1788908_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.20"
                     /molecular_weight="3123.4"
                     /monoisotopic_mass="3121.6"
                     /core_sequence="AAPPLATGRGLCDAAGARSPQVAAFPSQQDRP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MDRFLNPPILEQVGPRCRRGAENGRLAGS"
                     /leader_location="[1108:1195](+)"
                     /alternative_weights="3141.5"
                     /alternative_weights="3159.5"
     misc_feature    complement(1173..1186)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.42"
                     /tool="antismash"
     misc_feature    complement(1261..1270)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            1291..2715
                     /locus_tag="FEO89_RS08305"
                     /old_locus_tag="FEO89_08390"
     CDS             1291..2715
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1169: sugar
                     transport protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019661180.1"
                     /locus_tag="FEO89_RS08305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO89_08390"
                     /product="sugar porter family MFS transporter"
                     /protein_id="WP_154263117.1"
                     /transl_table=11
                     /translation="MTQAQPGTASQGGENTAFIVLISCVATLGGFLFGFDSGVINGTVD
                     GLRQAFNSSEAALGFEVASMLLGCAIGAFLAGWLGDRLGRRGVLIVSALLFLVSALGAG
                     AAHASWLFIVARVLGGFAVGAASVMSPAYIAEVASSRYRGRLATVQQMAIICGLFAAFL
                     SNYLLARAAGASTEPLWLGQEAWRWMFWMQALPSGLFLLLLLVIPESPRFLVLKGRQQQ
                     ARAVLSRLYGEAAAATKQAEIEASLAQDQHKPRFADLRDTVTGKLRPILWVGIGLAMFQ
                     QLVGINVVFYYGAVLWQAVGFSESDALLINVLSGALSIGACLLTVLLIDRIGRKPLLWI
                     GSVGMSVALVLMVVAFASGSLADGRLQLSDGMGRLALVAANVYVVFFNMSWGPVMWVML
                     GEMFPNQIRGPALAVAGAAQWTSNFAITVTFPMLLAGIGLAGAYGIYTVAAILSIFFVV
                     RYVRETKGKELEQMEG"
     tRNA            complement(3170..3244)
                     /anticodon=(pos:complement(1790823..1790825),aa:Glu,
                     seq:ctc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="FEO89_RS08310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="FEO89_08395"
                     /product="tRNA-Glu"
     gene            complement(3170..3244)
                     /locus_tag="FEO89_RS08310"
                     /old_locus_tag="FEO89_08395"
     misc_feature    3188..3203
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.79"
                     /tool="antismash"
     gene            3297..4676
                     /gene="pcnB"
                     /locus_tag="FEO89_RS08315"
                     /old_locus_tag="FEO89_08400"
     CDS             3297..4676
                     /EC_number="2.7.7.19"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:1990817 - poly(A) RNA polymerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006378 - mRNA polyadenylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pcnB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005416117.1"
                     /locus_tag="FEO89_RS08315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO89_08400"
                     /product="polynucleotide adenylyltransferase PcnB"
                     /protein_id="WP_154264937.1"
                     /transl_table=11
                     /translation="MGNPETSTGSANIISSATSPFSLRVIPRDQHTISRKDISPNALRV
                     LYRLRDAGFGAYLVGGAVRDLLVNGQPKDFDVATDATPEQVKQLFRNCRLIGRRFRLAH
                     VVFGREIIEVATFRANSDDGSGDREMENGMLVRDNVYGTIEDDAVRRDFTCNALYYAIE
                     DFSVRDYTGGFEDVQARLMKLIGDPEQRYQEDPVRMLRAVRLAAKLGFQIEEGTAAPIP
                     HLAGLLNEAAPARLFEEVLKLFLSGHGVASFEGLERYGLLDVLFPESAKALKSNRTGAL
                     RRMLVEGLANTDARVANDEPVSPSFLFALLLWPAFCRAQATLLKQGVAPEEAQRRAADR
                     VTVQQLSTIALPRRFSLPMQEIWLLQSRFGSRQRKRVFRTLTHPRFRAAFDFLSLRQVA
                     SAEHAADVEFWREAQAQSARELESSLDVMLSEEGDGESGAPRKRRRRRRRPGAPAGAAG
                     E"
     gene            4681..5166
                     /gene="folK"
                     /locus_tag="FEO89_RS08320"
                     /old_locus_tag="FEO89_08405"
     CDS             4681..5166
                     /EC_number="2.7.6.3"
                     /GO_function="GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA]"
                     /GO_process="GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="folK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019338321.1"
                     /locus_tag="FEO89_RS08320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO89_08405"
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="WP_049423508.1"
                     /transl_table=11
                     /translation="MTLAWIGLGANLGDAAVTVGAAIAALDDLPGTRLSQASRLYATPA
                     WGNEDQPPFVNAVAAVETTLPADTLLQAMLALEQRFGRVRDPAVHWGPRALDLDLLLYG
                     AQVLDQPGLQVPHPYLHERAFVLVPLAEIAPDLAIPGHGRVRDAVMRVDACGIAPIG"
     gene            5201..6016
                     /gene="panB"
                     /locus_tag="FEO89_RS08325"
                     /old_locus_tag="FEO89_08410"
     CDS             5201..6016
                     /EC_number="2.1.2.11"
                     /GO_function="GO:0003864 - 3-methyl-2-oxobutanoate
                     hydroxymethyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="panB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005416119.1"
                     /locus_tag="FEO89_RS08325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO89_08410"
                     /product="3-methyl-2-oxobutanoate hydroxymethyltransferase"
                     /protein_id="WP_049423510.1"
                     /transl_table=11
                     /translation="MSTHADSKPWTVPALAEAKRNGQKLVMLTAYDAGFARTFDANGID
                     LILIGDSLGMVVQGHDSTLPVTVADMVYHTRAVARVLQRALLVADLPFGADATPERALD
                     ASLQLLQAGAEMVKIEGAGFKVDIIRYLVEREIPVCAHLGLTPQSVLRLGGFKIQGRGD
                     AARQLVEDARAVAAAGASIMVLECVPTPVAAEVTAAVDVPTIGIGAGPQCDGQVLVLHD
                     FLGLDSGHRRPKFVKDFLAEGGSVAGATRAYADAVRDGSFPDEQHAYAQ"
     gene            6013..6852
                     /gene="panC"
                     /locus_tag="FEO89_RS08330"
                     /old_locus_tag="FEO89_08415"
     CDS             6013..6852
                     /EC_number="6.3.2.1"
                     /GO_function="GO:0004592 - pantoate-beta-alanine ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="panC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011259031.1"
                     /locus_tag="FEO89_RS08330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO89_08415"
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="WP_154263119.1"
                     /transl_table=11
                     /translation="MIQTFNELGALREQIAQWKREGLRVALVPTMGNLHGGHHSLVTLA
                     RQYADKVVASIFVNPTQFGPNEDFSRYPRTPEADVAGLEQAACDAVWLPSVEVMYPLGV
                     DKTTRMHAPGVSEVLEGASRPGHFDGVCTVVARLFLQVQPDVAVFGRKDYQQLAVIRQM
                     VAELSFPIQIVGADIVRDEDGLAKSSRNQYLSAEQRPLATTIHRTLLGMREGYVAGQAR
                     DRIEADATAALQAAGFQVDYAVLRTPELAEPTFDGGGRVALIAARLGTTRLIDNLEF"
     gene            6919..7416
                     /locus_tag="FEO89_RS08335"
                     /old_locus_tag="FEO89_08420"
     CDS             6919..7416
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005412963.1"
                     /locus_tag="FEO89_RS08335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO89_08420"
                     /product="hypothetical protein"
                     /protein_id="WP_154263120.1"
                     /transl_table=11
                     /translation="MKTPSTDTGRLAQASILAVLAAGMLPAQLFGGLLFALEFRRTPMP
                     ALTGGALMFVLAVSNAIAVLLPMALILQSQQRLRRTGFVLVGLGLGALAMATCTWPGAD
                     NGPLLQRLRYVDTFDVISRALQVLAAGGFGLVAGLAFHTVFRLSLEGSSGRAAPPPPGE
                     GA"
     misc_feature    7180..7182
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7504..7884
                     /gene="panD"
                     /locus_tag="FEO89_RS08340"
                     /old_locus_tag="FEO89_08425"
     CDS             7504..7884
                     /EC_number="4.1.1.11"
                     /GO_function="GO:0004068 - aspartate 1-decarboxylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="panD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011036943.1"
                     /locus_tag="FEO89_RS08340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO89_08425"
                     /product="aspartate 1-decarboxylase"
                     /protein_id="WP_154263121.1"
                     /transl_table=11
                     /translation="MHLSLLKTKIHRATVTHSELNYEGSIAIDDDLLAATGIREFEQVH
                     IWDVTNGARFSTYAIRAEAGSGVVSLNGGAARHVQVGDIIIIAAFASMTEQEADSFKPK
                     LVYVDGKNQITHTNDTIPTQAA"
     gene            7881..9395
                     /gene="pgi"
                     /locus_tag="FEO89_RS08345"
                     /old_locus_tag="FEO89_08430"
     CDS             7881..9395
                     /EC_number="5.3.1.9"
                     /GO_function="GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pgi"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019300464.1"
                     /locus_tag="FEO89_RS08345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO89_08430"
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="WP_049423515.1"
                     /transl_table=11
                     /translation="MTTNNGFDSLHSHAQRLKGASIPSLLAAEPGRVQDLALRVGPLYV
                     NFARQKYDAAALQALLALAAERDVGGAITRLFRGEQVNLTEGRAALHTALRGDVVDAPV
                     AAEAYATARGIRQRMGVLVRALEDSGVTDVVSVGIGGSDLGPRLVADALRPVTGARLRV
                     HFVSNVDGAAMQRTLATLDPAKTAGILISKTFGTQETLLNGQILHDWLGGSERLYAVSA
                     NPERAAKAFAIAADRVLPMWDWVGGRYSLWSAVGFPIALAIGFERFEQLLEGAAQMDAH
                     ALDAPLERNLPVLHGLTDIWNRNLLGHATHAVMTYDQRLALLPAYLQQLVMESLGKRVQ
                     RDGQPVTTDTVPVWWGGAGTDVQHSFFQALHQGTSIVPADFIGCVHNDDPYTINHQALL
                     ANLLAQTEALANGQSSDDPHRDYPGGRPSTLILLDALTPQALGALIAMYEHAVYVQSVI
                     WNINAFDQFGVELGKQLASGLLPALQGEDVAIADPMTREILAQLKG"
     CDS             9463..9621
                     /gene="allorf_1797077_1797235"
                     /locus_tag="allorf_1797077_1797235"
                     /protein_id="allorf_1797077_1797235"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MHECPRGHAFRVVSVLRMRRIRVPAAAQLDCASRANAVCTGGCTC
                     HPVSLAA"
     CDS_motif       9463..9540
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MHECPRGHAFRVVSVLRMRRIRVPAA"
                     /locus_tag="allorf_1797077_1797235_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9541..9621
                     /prepeptide="core"
                     /locus_tag="allorf_1797077_1797235_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.30"
                     /molecular_weight="2447.8"
                     /monoisotopic_mass="2446.1"
                     /core_sequence="AQLDCASRANAVCTGGCTCHPVSLAA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MHECPRGHAFRVVSVLRMRRIRVPAA"
                     /leader_location="[9462:9540](+)"
     misc_feature    complement(9542..9558)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 21.78"
                     /tool="antismash"
     misc_feature    9705..9723
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: medium, score: 27.95"
                     /tool="antismash"
     gene            9712..9918
                     /locus_tag="FEO89_RS08350"
                     /old_locus_tag="FEO89_08435"
     CDS             9712..9918
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268305.1"
                     /locus_tag="FEO89_RS08350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO89_08435"
                     /product="DUF6229 family protein"
                     /protein_id="WP_049423517.1"
                     /transl_table=11
                     /translation="MDLNDDVVSGWLNGSDDVDGCANPAGSLFIYGAAATESALTSASD
                     TLITGGGTECTTTMSVVNHCLCC"
     CDS_motif       9712..9810
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MDLNDDVVSGWLNGSDDVDGCANPAGSLFIYGA"
                     /locus_tag="FEO89_RS08350_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9811..9918
                     /prepeptide="core"
                     /locus_tag="FEO89_RS08350_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.70"
                     /molecular_weight="3233.6"
                     /monoisotopic_mass="3231.5"
                     /core_sequence="AATESALTSASDTLITGGGTECTTTMSVVNHCLCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MDLNDDVVSGWLNGSDDVDGCANPAGSLFIYGA"
                     /leader_location="[9711:9810](+)"
                     /alternative_weights="3251.6"
                     /alternative_weights="3269.6"
                     /alternative_weights="3287.7"
                     /alternative_weights="3305.7"
                     /alternative_weights="3323.7"
                     /alternative_weights="3341.7"
                     /alternative_weights="3359.7"
                     /alternative_weights="3377.8"
     gene            10001..12898
                     /locus_tag="FEO89_RS08355"
                     /old_locus_tag="FEO89_08440"
     CDS             10001..12898
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019338325.1"
                     /locus_tag="FEO89_RS08355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO89_08440"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_154263123.1"
                     /sec_met_domain="DUF4135 (E-value: 3.4e-79, bitscore:
                     264.7, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.2e-32, bitscore:
                     111.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTASPAAAAFARITEHFLAHARAALAAGLHDPAIALQPGERELLH
                     AQGDAALREHAQLKLNRVLLLELHAAARGGDIGPLDSAGALDEFVTLATSEGFHEHLQR
                     RYPVLLPRLSRMLEGQCAAVVELAARIGNDRALLTDLLDAPAGALRAIALGRGDLHGGG
                     RTVARLQFDGGVLMYKPRSLRIDAALDGLLAAVFGEGPDRVRVPRVVDRGSHGWAAFAA
                     HRHCADDEELRAYYRGLGHWLAILRLVGGTDIHLENLIAVGPVPVVIDAESVFSQVIDV
                     EPSGLGDAYDTAIKLMRNSVLRTGIVPFRTTGLGMEGVDLSAAGALPGEQPRVQVPVIV
                     EDGPGPARLGMVEAEVAIAQNHPSPQPDVSLYWDHISEGFIDASGRLRALDAKGELMPL
                     LAAFEGCQVRDVRRPTMAYAELGRMLWHPASLHKEAQAVERAIDLLVRNAAVSPAAPSD
                     LETVRGEVDDLRHGDIPIFTSQLDATRIRSIADNWRAMRIDLEDVTIRSTLVATDLNQH
                     ALARAEARSGYSYAAQHPRADDLDARRRTLAARAVESLLRLAVHGEDGSMTWITPEVTR
                     TGWTVQPVQPDLYFGLGGIAFALAAYRREVEQGRADPVAGLGPAIEGAIAVFQTMCERH
                     PAGIDGGFVGTGSQIWTLLALHDLLQRPGLLALAERCAEGVERRGFQGPVKFELIDGVS
                     GMILPLLALAEATGRSRWLELAAAAGRRMQEAAIVDADGARWPTPQFREPIGGFGHGAM
                     GMGWALARLARSDAGSVPERAAWRQLAEGAFAFQAALFEPHTGRWRDIHLQDGQKNFPT
                     WCHGSVGIGLAAADLYARTGDPAQLRDMRRAVADARGKWGFSHTLCHGDVSTRELLVLA
                     AALDPEGCPYPQDEAAIEIVSSIEEHQGMVGGLTRAAFTPGLMIGLAGAIYGFLRMHPA
                     CALPSPLLQETAAARVDAPASRSSAAQDRPALAEV"
     misc_feature    12335..12337
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12920..13489)
                     /locus_tag="FEO89_RS08360"
                     /old_locus_tag="FEO89_08445"
     CDS             complement(12920..13489)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012510702.1"
                     /locus_tag="FEO89_RS08360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO89_08445"
                     /product="response regulator transcription factor"
                     /protein_id="WP_012510702.1"
                     /transl_table=11
                     /translation="MSLHHSTLGLLVDDDELYLRTLQRSLARKGLETQTAQDAASALAL
                     ARQHPPAFALIDLKLGSDSGLALIQPLRALRADMRILLVTGYASIATAVEAIKLGADDY
                     LPKPATVPMILRALGEEDDGPADDGEMEVPDAMTPISRLQWEHIQQAMHETGGNVSAAA
                     RLLGMHRRSLQRKLAKRPSPERDPSR"
     gene            complement(13486..14712)
                     /locus_tag="FEO89_RS08365"
                     /old_locus_tag="FEO89_08450"
     CDS             complement(13486..14712)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019661188.1"
                     /locus_tag="FEO89_RS08365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO89_08450"
                     /product="ATP-binding protein"
                     /protein_id="WP_154263124.1"
                     /transl_table=11
                     /translation="MTGPDAPFLRTLCSLRWLAVGGQAATILVATWVLGLPLPQLPLWA
                     GVAVLTLFNIYTQLRPEAADTAPLTAFGHILVDVIILTWMVGWSGGMANPFSSLFLILI
                     ALAAFALPLRWALAVALACLLGYAASGIFGQSLPDGYFRAQDLNRWGVVANFLISAAVV
                     LTFSTRLALALRQRELELSALRERFARNEGIVALATHAASVAHELNTPLATMTLLADDV
                     AERSEEPEVREDMETLRELLVQCRERVLALAAPASANAPGRSHSSAQQVLEQWRLVRPT
                     IDLHRNDDAPLRLPLDPGVGHLLMVLLNNAADAGEQAGRPRVDLDLRIEGDDLIGEVRD
                     YGHGFDARAAVLPGKLFGSSKSEGMGVGLALSHATIERLDGEMWMRPAQGAGSRVGFRL
                     PLAPREDTP"
     misc_feature    14782..14800
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.46"
                     /tool="antismash"
     gene            14827..16092
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="FEO89_RS08370"
                     /old_locus_tag="FEO89_08455"
     CDS             14827..16092
                     /EC_number="1.17.7.1"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity [Evidence IEA]"
                     /GO_process="GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019300453.1"
                     /locus_tag="FEO89_RS08370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO89_08455"
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_106467705.1"
                     /transl_table=11
                     /translation="MHDAVTRPTPPSDATAWPRRQTHAVQIGGVTVGGGKPVVVQSMTN
                     TDTSDVASSVKQVAELWRAGSEMVRLTVNTVEAAAAIPRIVDKLAMMGIDVPLIGDFHY
                     NGHQLLTAEPACAEALAKYRINPGNVGFGKKKDLQFAQLIEFAIRYNKPVRIGANWGSL
                     DQALAAKLMDENNLREQPWDAGRVLREALIRSALDSAEQAVELGLPRDRIVLSAKVSGV
                     QELIAVYRDLAQRSDFALHLGLTEAGIGSKGIVASSAALSVLLQEGIGDTIRISLTPEP
                     GQSRTQEVIVAQELLQTTGQRAFTPLVTACPGCGRTTSEFFQELAKVVQNHVREKMPLW
                     KIHHPGAENMTLAVMGCIVNGPGESRHANIGISLPGTGETPAAPVFVDGEKKVTLRGDN
                     IAQEFVALIDDYVEHKYVRSAG"
     gene            16073..16822
                     /locus_tag="FEO89_RS08375"
                     /old_locus_tag="FEO89_08460"
     CDS             16073..16822
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005409066.1"
                     /locus_tag="FEO89_RS08375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO89_08460"
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_088025646.1"
                     /transl_table=11
                     /translation="MSEAPDKPAILAAPESASGFRHWMARNAWRLVLLFGGVLLPLAGF
                     VALADEVHEFESFHFDAPLLWQMHGLHSPWLDRFFVLISKLGYEWFLIPADVLIIGVLL
                     GYRRWREATFVAVSFVGSALLNMGSKHFFQRQRPSLWESIAPESTFSFPSGHAMGSMTL
                     AVTLVLLAWNTRWRWPVLLLAPAFSLLVSVSRVYLGVHYPSDILAGWCAALVWVVGCYL
                     VMFSRRHPWRRHGSPPAKASEASSQGV"
     gene            17023..>17445
                     /locus_tag="FEO89_RS08380"
                     /old_locus_tag="FEO89_08465"
                     /pseudo=""
     CDS             17023..>17445
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011408972.1"
                     /locus_tag="FEO89_RS08380"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FEO89_08465"
                     /product="response regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTIRVYLVDDHALVRTGMKMILSGETDIEVVGEAETGEDALREVR
                     QLLPDVVLCDLHLPGVSGMEVTERIVRSHRNTRVVIVSVLEDGPLPKRLLEAGAAGYIG
                     KGCDAQELLRAVRDVAGGRRYLGTSIAQNLALSTVEG"
     gene            complement(17599..18396)
                     /locus_tag="FEO89_RS08385"
                     /old_locus_tag="FEO89_08470"
     CDS             complement(17599..18396)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FEO89_RS08385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FEO89_08470"
                     /product="hypothetical protein"
                     /protein_id="WP_154263125.1"
                     /transl_table=11
                     /translation="MLIGFSPASVTAAADGATAANIAALVDGRPTSITRLSGGASAVRL
                     RLTWPAAAGVRVVGMLGLSCPVGTSLKLTGRKAGDATYGQALGGASITQKVVELVDGSR
                     AAWWVLPAGTVALVGIQVEIGVAGLDVGELFAHQAVDLPIEPGSETERIDPSIVERTLG
                     AGVNVVARRTYRRLRFTPQTDRLQVARQGGLGGGMDWERLAMAAAGGARMSLVPRWGRD
                     GALDTEELHRTALYGTVVAGSAGHAGGNQFRSGGWVADELPPI"
     gene            complement(18407..20374)
                     /locus_tag="FEO89_RS08390"
                     /old_locus_tag="FEO89_08475"
     CDS             complement(18407..20374)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FEO89_RS08390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FEO89_08475"
                     /product="hypothetical protein"
                     /protein_id="WP_154263126.1"
                     /transl_table=11
                     /translation="MRTFGRWAASPLGAGLLVEDGGLTVASPGAVVLARIARSTFPLTG
                     PAGAEFMLWGDDPLTAIIGLCNAAAPLSSELGASNGVGWKLHTGQVVRNGTVIASGLPI
                     PAKGEALGVRVLPGTPAQAQFYRDGQQVASVDVSAGGPYYFAVSIAATKARGLRCIVNA
                     GQWQGLSPAALAGWAQAADAIPAIRVASEDYMSAASDSPANTAFAGVIATEGLSTISAV
                     SFWMWGNESRAGSAQVRVQDAAGMLDAAALSAIRDVPVTVRQVEQGQSMAGAVPVARYV
                     LDRIEVEDDSYKRLTFKDAHSDLDGPLSRAVFLPTHGESIAWQPQPVVIGLVRSVPTTA
                     VNSDGSLQWICDSRLQSVMNVRDRAVELVAGTAYSLVAGGQQLSLQSPPLGPLTADVST
                     IGADRPATLQQALSDVFGRIGKAAWQSADALAIDQATGYAGVGYFADGNSTPREALAAI
                     LGSYCADWWQDGDGVLRLARLIDPESVADANLAFELDLVELAAPLVVLPDLAPGLTRRM
                     GYRPNAVVLADGDMATGLDQVPPSIRKELSASHRGQVYATGDLPACYQHAEAAPAVESC
                     FDSRADAQAEIDRVVKLYAVPRNFYAGRMTARPDLQLRPGQVGRIRYPRYGLAAGRKVI
                     VTAVTSNPITGEQTLKFWGA"
     gene            complement(20381..20572)
                     /locus_tag="FEO89_RS08395"
                     /old_locus_tag="FEO89_08480"
     CDS             complement(20381..20572)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FEO89_RS08395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FEO89_08480"
                     /product="hypothetical protein"
                     /protein_id="WP_154263128.1"
                     /transl_table=11
                     /translation="MRFDARLYLRTESADQPGVTLQFRPVSQPNMPQINLTVDTADAAA
                     LKVGAVYRFEATEITQEG"
     misc_feature    complement(20882..20900)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
ORIGIN
        1 gtcggcgccg catcatccgg cggccgacca ccttgccggc gacatcgccg ccctcgaagc
       61 cctttccagc cactgacctt ccgtcttggt ctgacccagg agattcacat gcgtcaatcc
      121 gtatccaccg tccgcgtgct gtcctacgcc ctgcttgcgg tggccgttgc cgccggcacc
      181 accggctgct tcaagcgtgg cgtcaagggc gactatgccc tggccccgga aatgcgtccg
      241 ctggaagtgc cgccggacct gaacctgccg accaccaccg gtgacaacaa ggtgccgacg
      301 ctggcatcgg cgaccaagcc ggcggccccg gtggctgcgg ccccggccgt gggcaatacc
      361 ggtttcacca tcgccggtgg caaggacgag gctttcgcca aggtcggcac cgcgctggaa
      421 ggcgtggagg gcgtgaccat cgcaagccgc gcgcagctgc tgggctcgta tgacgtggcc
      481 tacgaaggca gcaacttcct ggtccgcgtg gtcgccgtcg atgccggcgc ctacatctcc
      541 gcggtcgacc cgcgtggcct gccggccact gcagaagcgc cggtgaagct gatcgccgcg
      601 ctcaaggcga agctggccca gtaagggccg gtcgggtggg tgcgggccca ggtctgcacc
      661 ggcccgggta gaggccgacc ttggtcggcg cttctgtgcc aaccaaggtt ggcacctacc
      721 gagaacagaa aagggcgccg atgggcgccc tttccgttgc cgcagcaggc gcttctcagc
      781 gctccagcag cttcagcttg tccggcttgc cgtcccattc gccggcgtcg gcgggcgggt
      841 ccttgcgcac ggtcagcacc ggccactcct tcgccagctc ggcgttgagg gcgacgaagc
      901 tctcctggcc ggcaggaaca tcgtcttccg ggaagatcgc gttgaccggg cattccggtt
      961 cgcagagggt gcagtcgatg cactcatccg ggtcgatcac caggaagttc gggccttcgt
     1021 ggaagcaatc cacggggcat acttccacgc aatcggtgtg tttgcacttg atgcagtttt
     1081 cggtgacgac aaagggcatg ggctgggggt ggatcgattc ctgaacccgc caattctaga
     1141 acaggttggg ccccggtgtc ggcgcggggc ggaaaacggg cgtctggcag gctcggctgc
     1201 gcccccgttg gcgacagggc ggggcctgtg cgacgctgcg ggcgcccggt cgccgcaggt
     1261 ggccgccttc ccttcccagc aggatcgtcc atgacccaag cccagcccgg caccgcctcc
     1321 cagggcggcg agaacactgc gttcatcgtc ctcatcagct gtgtggccac cctcggtgga
     1381 ttcctgttcg gtttcgacag tggtgtcatc aacggtacgg tcgacggcct gcgccaggcc
     1441 ttcaattcca gcgaagcggc gctcggtttc gaagtcgcct cgatgctgct gggctgtgcg
     1501 atcggcgcgt tcctggccgg ttggctgggt gaccggctgg gccgccgtgg cgtgctgatc
     1561 gtgtcggcac tgctgttcct ggtgtcggcg ctgggtgccg gcgccgccca tgcctcctgg
     1621 ttgttcatcg tcgcgcgcgt gctgggtggc tttgcggtgg gggcggccag cgtgatgtcg
     1681 ccggcctaca ttgccgaagt cgcctcgtca cgctatcgag gacggctggc cacggtgcag
     1741 cagatggcca tcatctgtgg cctgttcgcc gccttcctca gcaactacct gctggcacgt
     1801 gccgccggtg cgtccaccga gccgctatgg ctgggccagg aggcctggcg ctggatgttc
     1861 tggatgcagg cactgccgtc ggggctgttc ctgctgttgt tgctggtgat tccggaaagc
     1921 ccgcgctttc tggtcctgaa ggggcgtcag cagcaggcga gggcggtact gtcgcggctg
     1981 tacggtgagg cggcagcggc gaccaagcag gccgagatcg aagccagcct ggcccaggat
     2041 cagcacaagc cgcgctttgc cgacctgcgc gacacggtca ccggcaagct gcggccgatc
     2101 ctgtgggtgg gtatcggcct ggccatgttc cagcagctgg tcggcatcaa cgtggtgttc
     2161 tactacggtg cggtgctgtg gcaggcggtg ggcttctcgg aaagcgacgc actgttgatc
     2221 aacgtgctgt ccggcgcgct gagcatcggc gcctgcctgc tgacggtgct gttgatcgac
     2281 cgcatcgggc gcaagccgct gctgtggatc ggctcggttg gcatgtcggt ggcgctggtg
     2341 ctgatggtgg tcgccttcgc cagtggcagc ctggccgatg gtcggctgca gctctccgac
     2401 ggcatgggcc ggctggcgct ggttgcggcc aacgtctatg tggtgttctt caacatgtcc
     2461 tggggcccgg tgatgtgggt gatgctgggc gaaatgttcc cgaaccagat ccgcggcccg
     2521 gcgctggcag tggccggcgc ggcgcagtgg acctcgaact tcgcgatcac ggtgaccttc
     2581 ccgatgctgc tggccggcat cggcctggcc ggggcctacg gcatctatac ggtcgcggcg
     2641 atcctctcga tcttcttcgt ggtgcgctac gtacgcgaga ccaagggcaa ggagctggag
     2701 cagatggaag gctgacaaat ctcggcttcg gacacgttcc gcctggcgcc tccgtgtcat
     2761 cgagggcgaa ggcggggcag cccaatccgg gacacgccgt aaacccttcc atgggggctc
     2821 gatggcgcca tccatggcgc caacggtccc ggcttgagct gccccgcctt cgcaccaggc
     2881 attgcggttc cggcggattt tccgaagcgc gccgtccggg cggttgccac cgccttcgcg
     2941 ggaaactgtc aggagggggc gggccaccct tgcctggacc gttggcgcca tggatggcgc
     3001 catcgagcac catggatggg cttttgcgtg tccaggcaag ggtggcccgc cccctctcac
     3061 gcaggagcag ggaggcgcca gagcgaccag cccgaccgca gccaccggca aacccggaaa
     3121 acagaaaagc ccgcgcaagg cgggcttttt cggttcctgc tgcggcgact ggcgctccct
     3181 aggggactcg aacccctgtt ttagccttga gagggccacg tcctaaccac tagacgaagg
     3241 gagcgtaact gtgtcgctgc cgaggcagga gcgctagtat atgcacctcg atgccattgg
     3301 gcaatcccga aacttcaacc ggaagcgcca acatcatttc ctctgctaca tcaccgttca
     3361 gcctgcgcgt catcccgcgc gaccagcaca cgatctcccg caaggacatc agcccgaacg
     3421 ccctgcgcgt gctttatcgc ctgcgcgatg ccggcttcgg cgcctacctt gtcggcggtg
     3481 cggtgcgcga tctgctggtc aatggccaac ccaaggattt cgacgtggcc accgacgcca
     3541 cgcccgaaca ggtcaagcag ctgttccgca actgccgctt gatcggtcgc cggttccgcc
     3601 tcgcccacgt cgtgttcggc cgcgagatca tcgaagtcgc caccttccgt gccaacagcg
     3661 acgacggcag cggcgaccgc gagatggaaa acggcatgct cgtgcgcgac aacgtgtacg
     3721 gcaccatcga agacgacgcc gtccgccgcg acttcacctg caacgccctg tactacgcca
     3781 tcgaggactt ctcggtgcgc gattacaccg gcggcttcga agacgtccag gcgcgcctga
     3841 tgaagctgat cggcgacccc gagcagcgct accaggaaga ccccgtacgc atgctgcgtg
     3901 cggtgcgcct ggcggccaag ctcggcttcc agatcgaaga gggcaccgcc gcgccgatcc
     3961 cgcacttggc cggcctgctc aacgaagccg caccggcacg cctgttcgag gaagtgctca
     4021 agctgttcct gtccgggcac ggcgtggcaa gcttcgaagg ccttgagcgt tacggcctcc
     4081 tcgacgtgct gttcccggaa agtgccaagg cgctgaagtc caaccgcacc ggcgcgctgc
     4141 gccgcatgct ggtcgagggg cttgccaaca ctgatgcacg tgtggccaac gacgagccag
     4201 tctcgccgtc gttcctgttc gcgttgctgc tgtggccggc gttctgccgc gcccaggcaa
     4261 ccctgctcaa gcagggtgtg gcaccggaag aggcgcagcg ccgtgccgcc gaccgcgtca
     4321 ctgtgcagca gctgagcacc atcgcgctgc cgcgccggtt ctcgctgccg atgcaggaga
     4381 tctggctgct gcagtcacgt ttcggctcgc gccagcgcaa gcgcgtgttc cgtaccctga
     4441 cccatccgcg tttccgcgct gcgttcgact tcctcagcct gcgccaggtg gcctcggccg
     4501 agcacgctgc cgatgtcgag ttctggcgcg aggcacaggc gcagtccgcc cgcgaactgg
     4561 aatcgtcgct ggacgtgatg ctcagcgaag aaggtgatgg cgagagcggg gcaccacgca
     4621 agcgccgccg tcgccgccgt cgtccgggcg cgccggccgg tgcggctggc gagtaaaacg
     4681 atgacccttg cctggatcgg cctcggcgcc aaccttggcg atgcggccgt caccgtcggc
     4741 gcggcgattg ccgcgctcga cgacctgccc ggtacgcgcc tgagccaagc gtcgaggttg
     4801 tacgccaccc cggcctgggg caatgaagat cagccgccgt tcgtcaacgc ggtggctgcg
     4861 gtcgagacca cgctgcccgc cgatacgctg ctgcaggcga tgctggcgct ggagcagcgt
     4921 tttggtcgcg tacgcgatcc ggcggtgcac tggggcccgc gcgcgctgga cctggacctg
     4981 ctgctgtatg gcgcgcaggt gctcgaccag cctggtctgc aagtgccgca tccttacctg
     5041 cacgagcgtg ccttcgtgtt ggtgccgctg gccgaaatcg cgccggatct ggccattccc
     5101 ggccatggcc gcgtgcggga tgcagtgatg cgggtggatg cctgcgggat tgcgccgata
     5161 gggtgataat gcccgggtta tctcccccgg ttatcagcac atgagcaccc acgcagacag
     5221 caagccctgg accgttcccg ccctggccga ggccaagcgc aatggccaga agctggtcat
     5281 gttgaccgcc tacgacgctg gcttcgcccg caccttcgat gccaatggca tcgacctgat
     5341 cctgatcggc gattcgctgg gcatggtcgt gcaggggcat gattcgaccc tgccggtgac
     5401 cgtggccgac atggtctacc acacccgcgc cgtggcccgt gtgctgcagc gcgcgctgct
     5461 ggtggccgac ctgccgttcg gtgccgatgc caccccggag cgcgcgctgg atgcatcgct
     5521 gcagctgctg caggccggtg ccgagatggt caagatcgaa ggtgccggct tcaaggtcga
     5581 catcatccgc tacctggtcg agcgcgagat tccggtctgc gcccatctcg gcctgacccc
     5641 gcagtcggta ttgcgcctgg gcggcttcaa gatccagggc cgtggcgatg ccgcgcgcca
     5701 gctggtggaa gatgccaggg cggtggccgc tgccggcgcc agcatcatgg tgctcgaatg
     5761 cgtgccgacc ccggtcgccg cggaagtgac cgcggcggtg gatgtgccga ccatcggcat
     5821 cggtgccggc ccgcagtgcg atggccaggt gctggtgctg cacgatttcc tcggcctgga
     5881 cagtggtcat cgccgtccca agttcgtcaa ggatttcctt gccgaaggcg gttcggtggc
     5941 tggtgccacc cgcgcctatg ccgacgcggt gcgcgacggc agtttccccg acgaacagca
     6001 cgcgtacgcc caatgatcca gaccttcaac gagctcggcg cgctgcgcga gcagatcgcc
     6061 cagtggaagc gcgagggcct gcgcgtggcg ctggtgccga ccatgggcaa cctgcatggt
     6121 ggccaccatt cgctggtgac cctggcccgc cagtacgccg acaaggtggt ggcgagcatc
     6181 ttcgtcaacc cgacccagtt cgggccgaac gaggatttca gccgctaccc gcgcacgccc
     6241 gaggccgacg tggccgggct ggagcaggcc gcctgcgatg cggtgtggct gcccagcgtc
     6301 gaggtgatgt acccgctggg cgtggacaaa accacgcgca tgcacgcgcc gggcgtgagt
     6361 gaagtgctgg aaggcgccag ccgtccgggg cacttcgatg gcgtgtgcac ggtggtggcg
     6421 cgcctgttcc tgcaggtgca gccggatgtg gccgtgttcg gccgcaagga ttaccagcag
     6481 ctggcggtca tccgccagat ggtggccgag ctgtcgttcc cgatccagat cgtcggtgcg
     6541 gacatcgtgc gcgacgagga tggcctggcc aagagttcgc gcaaccagta cctgagcgcc
     6601 gaacagcgcc cgcttgcgac caccatccac cgcaccctgc tgggcatgcg cgaaggctac
     6661 gtggccgggc aggcacgtga tcgcatcgag gccgacgcca cggcggcatt gcaggcggcc
     6721 ggtttccagg tcgactatgc ggtgctgcgg accccggagc tggccgagcc gaccttcgac
     6781 ggcggtggcc gcgtggcgct tatcgccgca cgcctgggta ccacgcgcct gatcgacaac
     6841 ctggagttct gagccacatg cggctccggg gcgcccgcaa cgggcgcctc tcgacttccc
     6901 acggacggga gaccggaaat gaagaccccc agcaccgata ccggccgtct tgcccaggcc
     6961 tcgatcctgg cggtgctggc cgccggcatg ctgccggccc agctgtttgg cggcctgttg
     7021 ttcgcgcttg aattcaggcg cacgccgatg cctgcgctca ccggcggtgc gctgatgttc
     7081 gtgttggccg tgagcaatgc gatcgcggtg ttgctgccga tggcgctgat cctgcagtct
     7141 caacagcggc tgcgccggac cggattcgtg ctggtcggct tagggctcgg cgcgttggcc
     7201 atggccacct gcacctggcc gggcgcggac aatggtccgc tgctgcagcg cctgcgctat
     7261 gtcgacacct tcgacgtgat cagccgtgcc ttgcaggtgc tggccgcagg tggcttcggc
     7321 ctggtcgccg ggctggcctt ccatacggtg ttccggctgt ctctggaggg cagttccggg
     7381 cgtgccgcgc cgccgccgcc gggggagggg gcctgaacag ccttcagcgt cctgctgcgg
     7441 ccccctgacg atggccaagc gggtgctaga atccgctctt tcctttgccg ttgcagcgcc
     7501 cccatgcacc tgtccctgct caagaccaag atccaccgcg ccaccgtcac ccattccgag
     7561 ctgaactacg aaggctcgat cgccatcgac gacgacctgc tggctgccac gggcatccgc
     7621 gagttcgagc aggtgcacat ctgggacgtg accaacggtg cgcgcttctc gacctacgcc
     7681 atccgcgccg aagccggcag cggcgttgtc tcgctcaacg gtggtgctgc gcgccacgtg
     7741 caggtcggtg acatcatcat catcgccgcg ttcgccagca tgaccgagca ggaagctgac
     7801 agcttcaagc cgaagctggt gtacgttgat ggcaagaacc agatcaccca caccaacgac
     7861 acgatcccga cccaggccgc atgacaacga acaacggatt cgactcgctg cactcccacg
     7921 cccagcgcct gaagggcgca agcattccca gcctgctcgc cgccgaaccc ggccgcgtgc
     7981 aggatctggc gctgcgggtc ggtccgttgt acgtcaactt cgcgcggcag aaatacgatg
     8041 ccgcggcgct gcaggcgttg ctggcgctgg ctgccgagcg tgatgtcggt ggcgccatca
     8101 cccgcctgtt ccgtggcgag caggtcaacc tgaccgaagg tcgcgcagcg ctgcataccg
     8161 cgctgcgcgg cgacgtggtc gatgcgccgg ttgcagccga ggcctatgcc accgcgcgtg
     8221 ggatccgcca gcgcatgggc gtgctggtgc gtgcgctgga agacagcggc gtcactgacg
     8281 tggtcagcgt cggcatcggt ggttccgatc tcggtccgcg cctggtcgcc gatgcgttgc
     8341 gcccggtcac cggtgcgcgc ctgcgcgtgc atttcgtatc gaacgtggac ggcgccgcca
     8401 tgcagcgcac actggccacg ctggatccgg cgaagaccgc cggcatcctc atctccaaga
     8461 ccttcggtac gcaggaaacc ctgctcaacg gccagatcct gcacgactgg ttgggcggca
     8521 gcgagcgcct gtatgcggtc agcgccaatc cggaacgcgc cgccaaggcc ttcgccatcg
     8581 ccgccgatcg cgtactgccg atgtgggact gggtcggtgg ccgttattcg ctgtggtcgg
     8641 ccgtcggttt cccgatcgcg ctggcaatcg gcttcgagcg ctttgaacag ttgctggaag
     8701 gcgcggcgca gatggatgcg catgcgctgg atgcaccgct ggagcgcaac ctgccggtgc
     8761 tgcacgggct gaccgacatc tggaaccgca acctgctggg ccatgccacg cacgcggtga
     8821 tgacctacga ccagcgtctg gcgctgctgc cggcctacct gcagcagctg gtgatggaaa
     8881 gcctgggcaa gcgcgtgcag cgcgacggcc agccggtcac caccgacacc gtaccggtgt
     8941 ggtggggcgg cgcgggcacc gatgtgcagc acagcttctt ccaggcactg caccagggca
     9001 ccagcatcgt tccggcagat ttcatcggct gcgtgcataa cgacgatccc tacacgatca
     9061 atcaccaggc cctgctggcc aatctgctgg cgcagactga agcactggcc aatggccaga
     9121 gcagcgacga cccgcaccgt gattacccgg gcggccgccc gagcacgctg atcctgctcg
     9181 acgcgctgac cccgcaggcg ctgggcgcac tgatcgccat gtacgaacac gccgtgtacg
     9241 tgcagtcggt gatctggaac atcaatgcgt tcgaccagtt cggtgtcgag cttggcaagc
     9301 agctggccag tggcctgttg ccggcgctgc agggtgagga tgtggcgatt gccgatccga
     9361 tgacccgcga gatcctggcg cagctgaagg gctgacccgg cctgcggatg tgccggcgcc
     9421 ggccggccat cccatgcctt tcccgttgcg ttcgatccgg tcgtgcatga atgtccgcgc
     9481 ggccacgcat tccgtgtcgt ttccgtgctg cgcatgcggc gcatccgcgt gcctgccgca
     9541 gcgcagcttg actgtgcatc gcgtgccaat gcagtgtgca cgggcggctg tacctgtcat
     9601 ccagtatcgc tcgcagcatg atgttgatgc cagggactgg ccgtatccga aggaacgtgg
     9661 aatcgatcca cgttctcaac gcctcatgtt gtgaatgaca ggagattgcg aatggatctg
     9721 aatgacgatg ttgtgtccgg ctggctcaat ggctcggacg atgtggatgg gtgcgccaac
     9781 cctgcgggtt cgctgttcat ctatggcgct gcggctaccg agtccgcact cacctcggcc
     9841 tccgacaccc tgatcaccgg tggtggcacc gagtgcacca ccacgatgtc cgtggtcaat
     9901 cactgcctgt gttgctgatg tagcccgagc cggcacgcag cgccttgcgg ctgcgtgccg
     9961 gcaactggaa cagacttccc gataccttgc agggggcgta atgaccgctt ctccggctgc
    10021 ggccgcgttt gcgcgcatca ccgaacattt ccttgcccat gcgcgtgccg cgttggcggc
    10081 cgggctgcat gaccctgcca ttgcgctgca gcccggtgag cgcgaactgc tgcacgcgca
    10141 gggcgatgcc gcgctgcgtg agcatgccca gctcaagctc aatcgtgtgc tgttgctgga
    10201 actacatgcg gctgcgcgcg gcggtgacat cggcccgctt gacagcgccg gtgcgctgga
    10261 cgaattcgta accctcgcca ccagcgaggg tttccatgaa catctgcagc gacgctatcc
    10321 ggtactgttg ccgcggctgt cgcgcatgct cgaaggacaa tgcgcggccg tggtggagct
    10381 ggcggcccgg atcggcaatg atcgtgcgct gctgacggac ctgctcgacg ctccggcagg
    10441 agcgctgcgt gcgatcgcgc tgggacgggg tgacctgcac ggcggcggcc ggaccgtggc
    10501 acggctgcag ttcgacggcg gcgtgctgat gtacaagccg cgctcgctac gcatcgatgc
    10561 ggcgctcgat ggcctgctcg ctgcggtctt tggcgagggc ccggatcggg tgcgtgtgcc
    10621 gcgtgtggtt gatcgcggca gccatggctg ggccgcattt gccgcgcacc gtcattgcgc
    10681 cgatgacgaa gaactgcgtg cctactaccg cggtcttggc cattggctgg cgatcctgcg
    10741 cctggtcggt ggtaccgaca tccatctgga gaacctgatc gctgtcgggc cggtgccggt
    10801 cgtgatcgat gcagaaagtg tgttctcgca ggtgatcgac gtcgagccgt cgggcctggg
    10861 tgacgcctac gacacggcca tcaagctgat gcgcaattcc gtactgcgca ccggcattgt
    10921 gccgttccgc accaccggcc tcggcatgga aggtgtggac ctgtcggccg ccggcgcatt
    10981 gccgggcgag cagccgcggg tacaggtgcc ggtgatcgtc gaggatgggc cggggccggc
    11041 ccggctgggc atggtcgagg ccgaagtcgc catcgcacag aaccacccca gtccacagcc
    11101 ggacgtttcg ttgtactggg accacatcag cgagggcttc atcgacgcca gtggacgcct
    11161 gcgcgcgctc gatgcgaagg gcgaactgat gccactcctg gcggctttcg agggctgcca
    11221 ggtgcgggat gtgcggcggc cgacaatggc ctacgccgag ctcgggcgga tgctctggca
    11281 tccagcctcg ctgcacaagg aagcccaggc ggttgaacgc gcgatcgatc tgctggtgcg
    11341 caatgcagcg gtgtcaccgg ctgcgccatc ggacctggaa accgtacgtg gagaagtgga
    11401 cgacctgcgc cacggtgaca ttccgatctt cacttcgcag ctggacgcga cccgcatccg
    11461 ctccatcgcc gacaactggc gtgcgatgcg catcgacctc gaagacgtga ccatccgcag
    11521 cacgttggtg gccaccgacc tgaaccagca tgcgctggcc cgcgccgagg ctcggtccgg
    11581 ctacagctat gccgcacagc atccgcgtgc ggacgacctg gatgcacgcc gtcgcacgct
    11641 ggccgcgcgc gcggtggaga gcctgctgcg gctggcggtg cacggcgaag acggttcgat
    11701 gacctggatc acacccgagg tgacccgtac cggatggacc gtccagccgg tgcagcccga
    11761 cctgtatttc gggctggggg gcattgcatt cgcgctggcg gcctaccgcc gggaagtgga
    11821 gcagggccgc gccgatccgg tggctgggct gggtccggcc atcgaaggcg ccattgcggt
    11881 gttccagacc atgtgcgagc gccatcccgc cgggatcgat ggtggattcg tcggcacggg
    11941 ctcgcagatc tggaccctgc tggcgttgca tgatctgctg cagcgcccgg gactgcttgc
    12001 gctggccgag cgctgtgcgg aaggagtgga acgtcgtggt ttccaggggc cggtgaagtt
    12061 cgaactgatt gatggcgtgt ccggcatgat cctgccgttg ctggcgctgg ccgaggccac
    12121 cggcagatcg cgctggctgg agttggcggc tgcggccggg cgccgcatgc aggaagcggc
    12181 gatcgtcgat gccgacggcg cacgctggcc gacgccacag ttccgcgagc cgattggtgg
    12241 ctttggccac ggcgcgatgg gcatgggctg ggcgctggca cggctggcgc gttcggatgc
    12301 cggcagcgtg cccgagcggg ccgcctggcg gcagttagcc gaaggagcgt ttgcgttcca
    12361 ggcggcgctg ttcgagccgc ataccgggcg ctggcgcgat atccacctgc aggacgggca
    12421 gaagaacttc ccgacctggt gccatggcag cgtcggcatc ggtctggcgg cagcggatct
    12481 gtatgcccgc accggcgatc ccgcgcagtt gcgtgacatg cggcgggctg tggccgacgc
    12541 gcgcggcaaa tgggggttca gccacaccct gtgccacggc gatgtatcca cccgggagct
    12601 gctggtgctg gcggctgcgc tggatccgga gggatgtccc tatccgcagg acgaggccgc
    12661 catcgagatc gtttcttcga tcgaggagca ccagggcatg gtcggcggac tgacccgcgc
    12721 ggcctttact ccgggcctga tgatcggcct ggcaggggcg atctatggct tcctgcgcat
    12781 gcatccggcc tgcgcgctgc cgtcgccgtt gctgcaggag acggcggcgg cgcgggtcga
    12841 tgccccagca tcgcgttcca gtgccgcgca ggaccgaccg gcgctggccg aggtctgagc
    12901 cggacgggtc cggtcgcgat cagcggctgg gatcgcgttc cgggcttggc cgctttgcca
    12961 gcttgcgctg cagcgaacga cggtgcatgc cgagcaggcg cgctgccgcg gacacgttgc
    13021 cgccggtctc gtgcatcgcc tgctggatgt gttcccactg caggcggctg atcggcgtca
    13081 tcgcatcagg cacttccatt tcgccatcgt cggccgggcc gtcgtcttcc tcgccgaggg
    13141 cgcgcaggat catcggcacc gtggccggct tcggcaggta gtcgtcggca ccgagcttga
    13201 tcgcctccac cgcggtggcg atgctggcgt agccggtcac cagcaggatc cgcatgtccg
    13261 cgcgcagggc acgcaatggt tggatcagcg ccaggccgga atcgctgccc agcttcaggt
    13321 cgatcagcgc gaacgccggc ggatgctggc gggccagtgc cagtgcactg gcagcatcct
    13381 gtgcggtctg cgtttcaagc cccttgcggg ccaggctgcg ctgcagggta cgcaggtaca
    13441 gctcgtcgtc gtcgaccagc aggccgagag tggagtggtg aaggctcatg gggtgtcctc
    13501 gcgtggggcc agcggcaggc ggaagccgac gcggctgccg gccccctggg ccgggcgcat
    13561 ccacatctcg ccgtcgaggc gttcgatggt ggcatgggac agggccaggc cgacgcccat
    13621 gccctcgctt ttgctgctgc cgaacagctt gcccggcagc accgcggcac gcgcgtcgaa
    13681 gccgtggccg tagtcgcgga cttcgccgat caggtcgtcg ccttcgatgc gcaggtccag
    13741 gtccacgcgc ggccggccgg cctgttcgcc ggcatcggcg gcattgttga gcaggaccat
    13801 cagaagatgg cccacgcccg ggtcgagtgg cagccgcagc ggcgcatcgt cattgcgatg
    13861 caggtcgatg gtcggccgca ccaggcgcca ctgttccagt acctgctgag cgctggagtg
    13921 gctgcgaccc ggtgcattgg ccgaggccgg tgcggccagc gccagcacgc gctcgcggca
    13981 ctgcaccagc agctcgcgca gggtttccat gtcctcgcgc acttccggct cttcgctgcg
    14041 ctcggccacg tcatcggcga gcagggtcat ggtcgccagc ggcgtattca gttcatgcgc
    14101 caccgaggcg gcatgggtgg ccagggcgac gatgccctcg ttgcgggcga agcgttcgcg
    14161 cagggccgac agttcaagtt cgcgctggcg cagcgccagt gccaggcggg tggagaaggt
    14221 cagcacgacc gctgcggaaa tcaggaaatt ggcgaccacg ccccagcggt tgaggtcctg
    14281 ggcgcggaaa tagccatccg gcagcgactg gccgaagatg ccgctggcgg cgtagccgag
    14341 caggcaggcc agcgcgaccg ccagtgccca gcgcaggggc agggcgaacg cggcgagcgc
    14401 gatcaggatc aggaacagcg agctgaacgg gttggccatg ccgccactcc agcccaccat
    14461 ccaggtcagg atgatcacgt ccaccagaat gtggccgaat gcggtcagtg gcgcggtgtc
    14521 ggccgcctcc gggcgcagct gggtgtagat gttgaacagg gtcagtaccg ccacgcccgc
    14581 ccacaacggc agctgcggca acggcaggcc cagcacccag gtggcaacca ggatggtggc
    14641 ggcctggcca cctacggcaa gccagcgcag gctgcacagg gttcggagaa acggggcgtc
    14701 gggaccggtc attcacgctc atcgtatgcg ttcacgcgtg accgtgcctg cgacaatcgg
    14761 ccgcagccgt gccgccggct gaatgcgagt cacccggaat gcggaggcgg gcgttagaat
    14821 gcgcccatgc acgacgccgt tacccgcccg acgccccctt ccgatgccac tgcctggccc
    14881 cgccgccaga cccatgccgt ccagatcggc ggggtcaccg taggcggagg caagccggtc
    14941 gtggtgcagt cgatgaccaa caccgatacc tccgacgtgg cctccagcgt gaagcaggtg
    15001 gccgagttgt ggcgtgcggg ttcggaaatg gtgcggctga ccgtcaacac cgtggaagcc
    15061 gctgcggcga tcccgcgcat tgtcgacaag cttgcgatga tgggcatcga cgtgccgctg
    15121 atcggtgact tccattacaa cggccatcag ctgctgaccg ccgaaccggc gtgtgccgaa
    15181 gcgctggcca agtaccgcat caacccgggc aacgtcggct tcggcaagaa gaaggacctg
    15241 cagttcgccc agttgatcga gttcgcgatc cgctacaaca agccggtgcg catcggcgcc
    15301 aactggggct cgctggacca ggcactggcg gcgaagctga tggacgagaa caacctgcgt
    15361 gagcagccct gggacgccgg ccgcgtgctg cgcgaggcgc tgatccgctc ggcgctggat
    15421 tcggcagagc aggcggtgga gctcggcctg ccgcgcgacc gcatcgtact gtcggccaag
    15481 gtcagtggcg tgcaggagct gatcgcggtg taccgcgacc tggcccagcg ctcggatttt
    15541 gccctgcacc tgggcctgac agaggccggt atcggcagca agggcatcgt cgcctcgtcc
    15601 gcggcgctca gtgtgctgct gcaggagggc atcggtgaca ccatccgcat ctcgctgacc
    15661 ccggaaccgg gccagtcgcg tacgcaggaa gtgatcgtcg cccaggagct gctgcagacc
    15721 accggccagc gcgccttcac gccgctggtc acggcctgcc cgggctgcgg ccgcaccacc
    15781 tccgagttct tccaggagct tgccaaggtg gtacagaacc acgtgcgtga gaagatgccg
    15841 ctgtggaaga tccaccaccc gggtgcggag aacatgaccc tggcggtgat gggctgcatc
    15901 gtcaacgggc caggtgagtc gcgccatgcc aacatcggca tctcgctgcc gggcaccggt
    15961 gaaaccccgg ctgcgcccgt gttcgtcgat ggcgagaaga aggtgaccct gcgtggcgac
    16021 aacatcgccc aggaattcgt cgccctgatc gacgattacg tcgaacacaa gtatgtccga
    16081 agcgccggat aagcctgcga tcctcgctgc accggagtcc gcctccggct tccgccactg
    16141 gatggcgcgc aacgcctggc gcctggtcct gttgttcggt ggcgtactgc tgccgctggc
    16201 aggctttgtc gccctggcgg acgaagtgca cgagtttgaa tcgttccatt tcgacgcgcc
    16261 gctgctgtgg cagatgcatg gcctgcattc gccgtggctg gaccgcttct tcgtgctcat
    16321 ctcgaaactg ggctacgagt ggttcctgat cccggccgac gtgctgatca tcggcgtgct
    16381 gctgggctac cggcgttggc gtgaggccac cttcgtggcg gtcagcttcg tcggctcggc
    16441 gctgctgaac atgggcagca agcacttctt ccagcgccag cggccgagcc tgtgggaatc
    16501 gatcgcgccg gaatcgacgt tcagcttccc cagcggccat gcgatgggct cgatgaccct
    16561 ggcggtgacc ctggtactgc tggcctggaa cacccgctgg cgctggccgg tgctgctgct
    16621 ggcaccggca ttcagcctgc tggtcagcgt gtcccgggtc tacctggggg tgcattaccc
    16681 ctccgatatc ctggccggat ggtgtgccgc gctggtttgg gtggtagggt gctatctggt
    16741 catgttcagt cgccggcacc catggcgacg tcacggctcg ccgccagcga aggccagcga
    16801 agcatcatca cagggggttt gacgtggatg gccgttgagg gacgtctacg tgatagatca
    16861 gttgtttcgt tgcagcaggt tctgcaagac agggggcaag cacaacgcgc cgtactgtga
    16921 tgcgcaaggc agatcgccgc cgccgcattc cagacgcgct tgcagggtat cggcaccctg
    16981 cctagcttga cctgcaatgg ccgcattcga agaggtacgt gaatgacgat tcgagtctac
    17041 ctggtggatg accacgcgct ggtccgcacc gggatgaaga tgattctgtc gggggaaacc
    17101 gacatcgaag tggtgggcga agccgagacc ggcgaagacg cgctgcgtga agtccgccag
    17161 ctgctgcccg atgtggtgct gtgtgacctg cacctgccgg gtgtgagcgg catggaagtg
    17221 accgagcgca tcgtgcgcag ccaccgcaat acccgcgtgg tgatcgtgtc ggtgctggaa
    17281 gatggcccgc tgccgaagcg gctgctcgag gctggcgccg ccggttacat cggcaagggc
    17341 tgcgatgcgc aggagctgtt gcgcgctgta cgtgacgtgg ccggtggccg ccgttacctg
    17401 ggcaccagca tcgcgcagaa tctggcgctg tcgacggtgg aaggcatgta agcggacagt
    17461 cactctgcga aatcgggaca cggggtttgc agaatcccca gctctggcca gtcagggctg
    17521 aatcgacctt gtgagccccc tttgcctgac cgttcgatag cccctcaaac ggggttagaa
    17581 ccccgcctca agcggggctc aaatcggggg gagctcatcg gcgacccaac cgccgctgcg
    17641 gaactggttg ccgccagcgt gcccagcgga cccggccacc accgtgccat acagtgccgt
    17701 ccgatggagc tcctccgtgt ccagggcgcc atcccttccc cagcgcggca ccagtgacat
    17761 ccgcgcgcca cctgcagccg ccatagccag tcgctcccag tccatcccgc cccccaggcc
    17821 gccctggcgg gcgacctgca gacggtcggt ctgaggggta aagcggaggc gccggtaggt
    17881 gcgccgagcc accacgttga cgcctgcgcc caaggtgcgc tccacaatgc ttgggtcgat
    17941 gcgctcagtc tctgagccgg gctcaatggg taggtctacc gcctggtggg caaacagctc
    18001 gcccacgtca aggcccgcca ccccaatctc gacctggata cctaccaggg ccacggtgcc
    18061 cgctggaagc acccaccagg ccgcccggct tccatccacc agctcgacta ccttttgtgt
    18121 gatcgaggcc ccaccgaggg cctggccata ggtggcatcg ccagccttgc gccccgtgag
    18181 cttgagggag gtgccaaccg ggcaggacaa accgagcatg ccaacgacac ggacgccagc
    18241 ggcggctggc caggtcaacc gcagtcggac ggccgacgca ccgccgctga gtcgagtgat
    18301 gctggtgggc cgcccatcga ccagggcggc gatgtttgcg gcagtggcgc cgtcagcggc
    18361 agcggtaaca ctcgcagggg agaatccgat aagcatgtgg cagtccttat gcgccccaga
    18421 atttcagggt ctgttcgcca gtgatggggt tgctggtcac cgccgtgacg atcacctttc
    18481 gaccggctgc gaggccatag cgtgggtagc ggatgcgccc gacctggccc ggtcgcagct
    18541 gcaggtcagg ccgcgcggtc attcggccgg cgtagaagtt gcggggcact gcgtagagct
    18601 tcacgacacg atcaatctct gcctgagcgt cagcgcggct atcgaagcaa gactccaccg
    18661 ctggcgcagc ctccgcgtgc tggtagcagg caggcagatc cccggtggcg tagacctggc
    18721 cacggtggct ggcggacagt tccttgcgga tgctgggcgg cacctggtcc aggccggtgg
    18781 ccatatcgcc gtctgccagg actaccgcgt tgggccgata gcccatgcgt cgggtaaggc
    18841 ctggggccag atccggcagc acaaccagcg gagcggcgag ctcgaccagg tcgagctcaa
    18901 atgccaggtt cgcatcggca acgctctcag ggtcgatcaa tcgcgccagg cgcagcacgc
    18961 catccccgtc ctgccaccag tcggcgcagt agctgcccag gatcgcagcc aaggcctcgc
    19021 gcggcgtgct gtttccgtcc gcaaagtagc ccaccccggc atagcccgta gcctggtcga
    19081 tggcgagcgc gtcggcgctc tgccacgcgg ctttcccaat acggccgaac acgtctgaaa
    19141 gcgcctgttg aagcgttgcc ggccggtccg cgccgatggt cgaaacgtca gccgtcagcg
    19201 gcccgagagg cggtgactgc agggagagct gctgtccacc agcaaccagg ctgtacgcgg
    19261 tgccggctac cagttctact gcgcggtcac ggacattcat cactgattgc aggcgcgaat
    19321 cgcagatcca ctgcagcgaa ccatcactgt ttaccgccgt ggtcggtacg cttcgcacca
    19381 gcccgatcac cacgggctgg ggctgccagg caatgctctc gccgtgggtc gggagaaata
    19441 cggccctgct cagcggccca tccaggtcac tgtgcgcgtc cttgaacgtc aggcgcttgt
    19501 agctgtcgtc ttcgacctcg attcgatcca gaacataccg ggcgaccggc accgcaccgg
    19561 ccatcgactg tccttgctcg acctggcgca ccgtgactgg cacgtcacga atagcggaca
    19621 gcgcagcggc atccagcatc cctgcggcgt cctgtacgcg gacctgggcg ctgccggcac
    19681 gcgactcgtt cccccacatc cagaacgaaa ctgcgctgat cgtgctcagg ccctcggtag
    19741 ctatgactcc agcaaatgcg gtgttcgctg gcgagtcgct ggccgcgctc atgtagtcct
    19801 cacttgcgac gcggatcgcg gggatcgcat cggcagcctg cgcccatccc gccagtgcgg
    19861 ccggactgag cccttgccac tggccagcgt tcacgataca gcgcaggccg cgcgctttcg
    19921 tagcggcgat ggacacggcg aagtagtacg ggccacccgc tgagacatca acgctggcca
    19981 cctgctggcc atcacgatag aactgagcct gcgcgggtgt gccaggcagc acgcgcacgc
    20041 ccagcgcttc tcccttggcg ggaattggca ggccgctggc aatcaccgtg ccgttgcgaa
    20101 ccacttggcc ggtgtgcagc ttccaaccca ccccgttgga tgcgcccagt tcggatgaca
    20161 acggcgctgc ggcattgcag aggccgatga tcgcagtgag aggatcatca ccccacagca
    20221 tgaactcagc gccggcagga ccggtaagcg gaaaggtgct cctggcgatg cgagcaagaa
    20281 caacggcccc cggtgaggct acggtcaatc cgccatcctc taccagtaga ccagcaccga
    20341 gcggagacgc cgcccaacgg ccaaaggtac gcacgactgg tcaaccctcc tgggtgattt
    20401 cagttgcctc aaagcggtag acagcaccaa ccttcagcgc ggcggcgtcg gccgtatcga
    20461 ccgtgagatt gatctggggc atattcggct gactgactgg acggaactgc agagtcacgc
    20521 cgggctggtc agcagactcg gtgcgaaggt acaggcgagc atcaaagcgc atgggtgttt
    20581 cctcttattg gatgagcggc attgcccggc cgctggagcg ggtcactcct caatggagac
    20641 gatggaaagg ctggcggtga tgtctaggcc ggtgaaactt ccagtctgat ggctaacgtc
    20701 ctgttcgctg aacccgacga tctctgcacg gtaggtgcgg tcctgcgtgc cttcgctgtc
    20761 gttcaatgtt accgatccag accagaacga aatcgccata tctgggccat cggactcgtt
    20821 cgtaatcgac acgccgccgc tggcttcaaa gctcgtccag aactgctccg cgttgctgcc
    20881 cagtttcctg tagacattca ccgcgcaggc gttcctgttt ccgcctgcga cgaagccctg
    20941 gcgatccatt cggttgttgg ttcgcacgac agttcgctgg tagctgacaa cgacgttctt
    21001 gttccggccg cttgtgctga acgggccgac gacaatggaa gcgccaatgg tctgcgtagt
    21061 ggttgtctgc atcgcattgc ggcggacacc ggccgcaatg gcaccacccc agtacgcacc
    21121 accatttacg tccatccaca cggttgcgtt acgcttcgtt gcacccgcag cgccgacgtt
    21181 agggccgaaa tagtcgatca ggccatcagg cccgaagccg ttaccgatga tgcgttgtac
    21241 gttgccacgc cagacgcgca gatagccgtc ttggatctcc atgccgtctg gtgtgccagg
    21301 acttatcagg cgcaggatct tggagagaat ttttagctca ctctttgccc cggtcgcttc
    21361 catctccatg ccggagacat tgccattcac gtcgagcgca aagccccact tggcactact
    21421 ctctgaaccg ccggcattcc acgggggtgg cagcgtcgca tccggctcaa cccgcgagaa
    21481 cattgggcgg aacatccaga aatacggcca cgcctcaccg ttgggcttga cgatgatcct
    21541 gaaccgagcg agagcagctc taggaggtgc gacggtcttg atgcttgggc gtggcatctc
    21601 ggaaagcagt ggcgggccac tgttccccgt gtgccctgtt tccggtgagc cccattgcgc
    21661 aagccagttc cctgtcttgt cccagtaact gatctcgatg tagcaagagc agcggtgagt
    21721 gttgaaccag gcggaagcca tgtaggtttg gccggcttcg acagggatgc cgtactcagt
    21781 tccccaccag acaatttgcg ttgaggtagt gccaccggag gtcgagccga ctccatagat
    21841 gccaggggga tggaaactgt cgttgccggg agtcggatcg ccaagctcta cccatgctgc
    21901 accagggttc gagccccaac cccagccgtt gcgctgatac ttcgggaacg tcgaattgat
    21961 gagcagattc ccgccgctgc cctggttgtt gacctttgcc tcaagcgtct gaacgacaga
    22021 ggcgctggct tttcccttca cctcggcctg gacgccagtc accgactggc ccagcgccgt
    22081 gatctgctgc ccctgctggg taacagtcga agtaaggccc gccgtcgctg cagcgtttgc
    22141 catggccgct gcagcagatt ccatgctgct tggggcgtac tcggtagcca ctagaccgcg
    22201 ctgaaactgc acgttgtcga tttcgatggc gtgcgggcca ggttgctgcg cgaacaggcg
    22261 gcccgcgtaa acgcgggcga gcacggcatc gccgcgagag cgagcaggga ggagcaggcg
    22321 ctgccacttg ccggtcatag tcacctccgg cagggtcaca gtgcccaata ccgtgccacc
    22381 agtggcattc atccactgca cgtagagctg cgcccgcgcg tcaggcgtac cgcgcaccca
    22441 ggaggacaag gtgtagtcgg tgttagggtc cacctttaca tagttggagc ccggacctgc
    22501 tcgattcagg cccacccaat ccttcgcatt gatggcgttc cagtcgatgc gcaccgcttt
    22561 cccgccaccg ctcagcgggg actctatgaa ggagaaagtg cctcccacgt cgcttcggat
    22621 gcgctccagg ttccagccgg ttggtgctgc ggtagccacg ggggcgtctt ccatactgct
    22681 gttccacagc aggttgtcac caccgattgc gtcgatcctc gcattgacgc tggtgagtga
    22741 ctgacccaac gaggtaacgc tgctttcgtt ggccaaggtg cgtgcttcca agctggaatt
    22801 cgcagcagca tttgcctgtg tggcccgctc caacgcggac acgtccaggc tgccctgcgg
    22861 ccgcccattg acgaattcca cgatgagctc aacccatt
//
