LOCUS       NZ_CP040438            10846 bp    DNA     circular CON 07-MAY-2024
DEFINITION  Stenotrophomonas maltophilia strain PEG-173 chromosome, complete
            genome.
ACCESSION   NZ_CP040438
VERSION     NZ_CP040438.1
KEYWORDS    RefSeq.
SOURCE      Stenotrophomonas maltophilia
  ORGANISM  Stenotrophomonas maltophilia
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Stenotrophomonas; Stenotrophomonas maltophilia
            group.
REFERENCE   1  (bases 1 to 4769515)
  AUTHORS   Gonzaga,A. and Nubel,U.
  TITLE     Stenotrophomonas maltophilia genomes
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4769515)
  AUTHORS   Gonzaga,A. and Nubel,U.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-MAY-2019) Mikrobielle Genomforschung, Leibniz-Institut
            DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH,
            Inhoffenstrasse 7 B, Braunschweig 38124, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. v3.12.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150X
            Sequencing Technology             :: PacBIO + Illumina Miseq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009676565.1-RS_2024_05_06
            Annotation Date                   :: 05/06/2024 04:36:42
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,334
            CDSs (total)                      :: 4,244
            Genes (coding)                    :: 4,202
            CDSs (with protein)               :: 4,202
            Genes (RNA)                       :: 90
            rRNAs                             :: 5, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 22 of 42
            Pseudo Genes (incomplete)         :: 23 of 42
            Pseudo Genes (internal stop)      :: 2 of 42
            Pseudo Genes (multiple problems)  :: 5 of 42
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:36:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1288425
            Orig. end                         :: 1299271
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP040438.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..10846
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10846
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10846
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5846](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5846)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            242..1780
                     /locus_tag="FEO89_RS05945"
                     /old_locus_tag="FEO89_06005"
     CDS             242..1780
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1273: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014036331.1"
                     /locus_tag="FEO89_RS05945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO89_06005"
                     /product="TerC family protein"
                     /protein_id="WP_154262716.1"
                     /transl_table=11
                     /translation="MEWLADPSIWMGLATLVVLEIVLGIDNLVFIAILADKLPPHQRDR
                     ARVIGLALALLMRLVLLAALAWIMKLTEPLLTLFDHNFSGRDLILLGGGLFLLFKGTME
                     LHERLEGREHHEDGKKVYASFAMVVAQIVVLDAVFSLDSVITAVGMVDNLGVMYAAVTI
                     AMALMLVASKPLTRFVNKHPTVVVLCLGFLLMIGFSLVAEGLGYKIPKGYLYAAIAFSI
                     LVEAFNQWVRFNRERNERRQPFRQRTADAVLRMLGARPANGHDDESADEHVDAEERLQP
                     AEHEMIRSVLGLADRPVSSVMTVRADVQWIDLARGQEDVVARLVASPHTRLLVGDGDLD
                     SLRGVVQSRDLLAGLLQGRPLQLEGNLREPQYVLSSASALQALELIRQHPVPLAVAVDE
                     YGSVEGLVTANDLLAAIAGDLVDTQDERYGVVAQGEDCWEADGALTLDDLQRLAGVSLP
                     RSADYMTISGLVLERLGRLPDIGDTVEIADVRITVLAMEKRRIARLRVERIGLS"
     gene            1945..3081
                     /locus_tag="FEO89_RS05950"
                     /old_locus_tag="FEO89_06010"
     CDS             1945..3081
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004147841.1"
                     /locus_tag="FEO89_RS05950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO89_06010"
                     /product="metallophosphoesterase"
                     /protein_id="WP_154262718.1"
                     /sec_met_domain="Metallophos_2 (E-value: 1.7e-08, bitscore:
                     32.7, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVAVLSTIGLLMGLYVAWRLFWPLRMPVWMKVVLSLLLVGVAVQL
                     RIVAMFWGTMASPEIPKLAIASLATGSTAVLLLALVLLVLDAGLLVSRILRRPLAVSAL
                     RAPKLRPAAGVLALLVSGYGVSQGMAVPKPRQIEVSIAGLPAAFDGYRVLQLTDIHASR
                     LLTGDWVRRVVDESNALTPDLIVITGDLIDGSVEARRDDARPLADLHAPDGVIAITGNH
                     EYYAQYQSWMQAFRALHMQVLENSHLQVRRGDAALTIAGVTDPVAARYGLPLPDLGAAL
                     AGADPTAPVILLDHRPRNAREAAARGVKLQLSGHTHGGQIIGMDQLVKRANGGYVSGRY
                     DVDGMTLYVSNGAGLWAGFPARIGVRSEITLITLRRAP"
     gene            3155..3559
                     /locus_tag="FEO89_RS05955"
                     /old_locus_tag="FEO89_06015"
     CDS             3155..3559
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012510383.1"
                     /locus_tag="FEO89_RS05955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO89_06015"
                     /product="hypothetical protein"
                     /protein_id="WP_154262719.1"
                     /transl_table=11
                     /translation="MSHPRAPMERLIRANADEINRLRQVIRNTAGARWRGPEDRERHAA
                     ACAEFHQNYARLAFPGGYANALKRLAEHDPDTLDVALTFLEVRPYFFRSGYMWKTLLKR
                     VQRVSMGAKQHARLQGILDAYAAYRATRDG"
     misc_feature    complement(3177..3191)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.77"
                     /tool="antismash"
     gene            complement(3578..4216)
                     /locus_tag="FEO89_RS21935"
                     /old_locus_tag="FEO89_06020"
     CDS             complement(3578..4216)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005408497.1"
                     /locus_tag="FEO89_RS21935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO89_06020"
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="WP_154264922.1"
                     /transl_table=11
                     /translation="MAASNTSFLHGWRLFVTMAVVLIAVALAAFTLQPDVVEGSRAAIR
                     VTARTSFLLFLAAFTASSFASLLPGPFTRFLLRERRIIGLSFAFSHLLHAVAITSFGIL
                     NPAFWPARSALANLPGTVGYIAILALAITSHRGLARRMGPTAWRRLHVTGMWIIAAVFT
                     YSYFKRVPGNFWYAVPSALLFTAFVVRWIAKRAQALRRSAHARPPLRAV"
     misc_feature    4640..4654
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 19.02"
                     /tool="antismash"
     gene            complement(<4793..5032)
                     /locus_tag="FEO89_RS21940"
                     /pseudo=""
     CDS             complement(<4793..5032)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021364.4"
                     /locus_tag="FEO89_RS21940"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="putative DNA-binding domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MCCCRRWPMVDSLATLQQRWADHVRDPSMPAPDGIDARRLAVYRR
                     LCIDSLDSLLAGSLPRLQAQLGRARWRSLVEHYYA"
     gene            complement(5001..5846)
                     /locus_tag="FEO89_RS05970"
                     /old_locus_tag="FEO89_06030"
     CDS             complement(5001..5846)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646321.1"
                     /locus_tag="FEO89_RS05970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO89_06030"
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_154262720.1"
                     /sec_met_domain="DUF692 (E-value: 5.3e-120, bitscore:
                     397.6, seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLPLPSNAAGLGLRRGLIDELLAMPAGAIDFLEVAPDNWIGVGG
                     AHGAALRRLSERHPLTCHGLSLSLGGPDPLDRTLLAQTRDFLDLHQVQLYSEHLSYCTA
                     GGHVYDLLPLPFTDEAVHHAAGRIRQVQDTLGRRIAVENISYYAVPDAEMSEIDFINAV
                     LAEADCDLLLDVNNVFVNACNNGYDAFEFLARVPSHRVASLHVAGHFDEDDGFKIDTHG
                     APVKGVVWALLRAAYARVGVRPTLLERDFNFPPLAELLAEVEQIRQAQVDVLLPKVAHG
                     "
     gene            complement(5903..6379)
                     /locus_tag="FEO89_RS05975"
                     /old_locus_tag="FEO89_06035"
     CDS             complement(5903..6379)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005412584.1"
                     /locus_tag="FEO89_RS05975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO89_06035"
                     /product="EF-hand domain-containing protein"
                     /protein_id="WP_154262721.1"
                     /transl_table=11
                     /translation="MSVSTKTTLSSRLPRVGAIGIALAGGLLLAGQAAAIQPLAISAVA
                     MSAAAEGKCGEGKCGANKATTGKPAGKAKVAEGQCGEGKCGDASFARTDRDHDGKVSRA
                     EFNAVAAKRAAEFDRIDTDHDGYITEQEAHDYLRSVYTANSKPMPKGLFSRVAD"
     gene            complement(6473..7117)
                     /locus_tag="FEO89_RS05980"
                     /old_locus_tag="FEO89_06040"
     CDS             complement(6473..7117)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012479418.1"
                     /locus_tag="FEO89_RS05980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO89_06040"
                     /product="DoxX family protein"
                     /protein_id="WP_154262722.1"
                     /transl_table=11
                     /translation="MISTASSVYTPRLDAVGRWLSPLALRTLLAWEFFESGREKLGGQN
                     WFADLEGRFPFPFSTLPASLNWQLATWLELVGAVMLLLGLATRSVAYVFWVLTVVAIAA
                     VHWPDQWNGLGELWQGYAITDQGYGNFKLPLLFLAMLLPLILNGGGALSVDRLLAGSRH
                     APVGDDGLGWGVSLIALLLPVAALLPGIGFGGALLGGVLLLGHLLRRRRSA"
     gene            7459..8253
                     /locus_tag="FEO89_RS05985"
                     /old_locus_tag="FEO89_06045"
     CDS             7459..8253
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005408502.1"
                     /locus_tag="FEO89_RS05985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO89_06045"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_154262723.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.9e-16, bitscore:
                     59.3, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTSLLAAALALAGAAAPAFATQADTAAPPTVILVHGAFADGSS
                     WNRVISTLHDWKLPVVAVQNPLTSLADDVAATRRAIAAAPGRVVLVGHSWGGTVITEAG
                     DDPKVQALVYVAAFAPDAGQSSAQQGEGFPVGPGLARLQERDGYLTLPADAIAQDFAPD
                     VMKKSAALLYSTQVPLKASALGEVVNVAAWRSKPSWYVLSRDDRMLSPQLQAATAKRIG
                     AQLQSIGSSHVSLLSHPAQVADSILEAAGVKPAELPLAEQGG"
     gene            8257..8802
                     /locus_tag="FEO89_RS05990"
                     /old_locus_tag="FEO89_06050"
     CDS             8257..8802
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1241: lipoprotein
                     dsbF"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005415663.1"
                     /locus_tag="FEO89_RS05990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO89_06050"
                     /product="redoxin family protein"
                     /protein_id="WP_154262724.1"
                     /transl_table=11
                     /translation="MAALRGYALPLLLGLLGGAVLLLAWPGAEAGAQPLDAAPKAGFGG
                     GGPWRNSPPITLKQLRGQVVLVEFWTYTCSNCLNVAPYVHQWHARYASQGLQVIGVHTP
                     EFAYEGVPGNVRRAIGRLDITWPVVQDNQFRIWNAWGNRFWPALYLLDRQGRVVYRHYG
                     EGDYARTESEIQRLLASP"
     gene            8860..9600
                     /locus_tag="FEO89_RS05995"
                     /old_locus_tag="FEO89_06055"
     CDS             8860..9600
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019659345.1"
                     /locus_tag="FEO89_RS05995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO89_06055"
                     /product="response regulator transcription factor"
                     /protein_id="WP_049443785.1"
                     /transl_table=11
                     /translation="MNPVPHILVVDDDSEIRQMLADYLQRNGLRVSQADGGRAMRALMD
                     THAVDLVVLDVMMPGEDGLSLCRNLRAGKHRAVPVVLLTARDDETDRIIGLEMGADDYV
                     TKPFSSRELLARINAVIRRTRMLPPNLQVSEAGRQLAFGAWRLDTTARHLLDAQDTAYP
                     LSGAEFRLLRVFLDHANRVLSRDQLLSLTQGRDAELFDRSIDLLVSRVRQRLGDDAREP
                     TYIKTVRSEGYVFSVPVQLLGPDE"
ORIGIN
        1 catgctgcag gaacggggca tgaccctgtc cgagctggcc gggcgcatcg acatcaccct
       61 ggccaacctg tcgatcctga aaaccggcaa ggcgcgcgcc atccgctttt ccacacttga
      121 tgcgatctgc cgtgagctgc agtgcacgcc cggtgacctg ctcgggcatg actcggcgca
      181 ggcgcaggac gctgactgag tgtttcccct ttcccttacc tactgacgga acggacctga
      241 aatggaatgg ttggctgacc cctcgatatg gatgggcctt gcaaccctgg tcgtgctgga
      301 gatcgttctc ggcatcgaca acctggtgtt catcgcgatc cttgccgaca aactgccgcc
      361 gcaccagcgt gaccgcgcgc gggtgatcgg cctggcgctg gccctgctga tgcggctggt
      421 gctgctggcc gcgctggcat ggatcatgaa gttgaccgag ccgctgctca cgctgttcga
      481 ccacaacttc tccgggcgtg acctgatcct gctgggcggt ggtctgttcc tgctgttcaa
      541 gggcacgatg gaactgcacg agcggctgga gggccgcgag catcacgagg atggcaagaa
      601 ggtctacgcc agcttcgcga tggtggtggc acagatcgtg gtgctcgacg cggtgttctc
      661 gctggactcg gtgatcaccg cggtcggcat ggtcgacaac ctgggcgtga tgtacgccgc
      721 ggtgaccatc gcgatggcgc tgatgctggt ggccagcaag ccgctgaccc gcttcgtcaa
      781 caagcatccc acggtggtcg tgctgtgcct gggcttcctg ttgatgatcg gtttcagcct
      841 ggtggccgaa ggcctgggct acaagatccc gaagggttat ctgtacgcgg ccattgcttt
      901 ctcgatcctg gttgaagcct tcaaccagtg ggtgcgcttc aatcgcgagc gcaacgagcg
      961 ccgccagccg ttccgccagc gtaccgccga cgccgtgctg cgcatgctgg gcgcgcgccc
     1021 ggccaatggc cacgacgacg aaagcgctga cgaacacgtc gatgccgaag agcggttgca
     1081 accggccgag cacgagatga tccgcagcgt gctgggcctg gctgatcgcc cggtgtcgag
     1141 cgtgatgacc gtgcgtgccg acgtgcagtg gatcgacctg gcacgtgggc aggaggatgt
     1201 ggtggcacgc ctggtggcat cgccgcacac ccgcctgctg gtgggtgatg gcgacctgga
     1261 cagcctgcgc ggcgtggtgc agagccgcga ccttctggcc ggcctgctgc agggcaggcc
     1321 gctgcagctg gagggcaacc tgcgcgagcc gcagtacgtg ctgtccagcg ccagcgcact
     1381 gcaggcgctg gaactgatcc gccagcaccc ggtgccgttg gcggtggcgg tggacgagta
     1441 cggcagtgtg gaaggcctgg tgaccgccaa cgatctgctg gcggccattg ccggtgacct
     1501 ggtcgacacc caggacgagc gctatggcgt ggtggcgcag ggtgaagatt gctgggaagc
     1561 cgatggcgcg ctgaccctgg acgacctgca gcgcctggcc ggcgtctcgc tgccgcgcag
     1621 tgccgactac atgaccatct ccggtctggt gctggagcgt ctggggcgcc tgccggacat
     1681 cggtgacacg gtggagattg cggatgtacg catcaccgta ctggcaatgg aaaagcgtcg
     1741 catcgcccgc ctgcgggttg aacgcatcgg gctttcgtag agtcgagcct gctcgaccgg
     1801 ccctctgtag agtcgagccg tgctcgactg gccttctgta gagtcgagcc atgctcgact
     1861 gcttcctgag cagccgggta cgggctcggc tctacacaac acctcccgca accgtcacca
     1921 tgacgggccc gctttctttc ccggatggtt gcagtgctga gtacgatcgg tttgttgatg
     1981 ggcctgtatg tggcctggcg cctgttctgg ccactgcgca tgcccgtctg gatgaaggtc
     2041 gtgctgtcgc tgctgctggt gggcgttgcc gtgcagctgc gcatcgtcgc gatgttctgg
     2101 ggcacgatgg cctcgccgga aattccgaag ctggccatcg cctcgttggc cacgggttcg
     2161 actgccgtac tgctgctggc gctggtcctg ctggtgctgg acgcgggcct gctggtgtcg
     2221 cgcatcctgc gcaggccact tgctgtttcg gcgttgcgcg cgccgaagct gcgcccggcg
     2281 gcgggtgtgc tggcgctgct ggtcagtggc tacggcgtca gccaaggcat ggcggtaccc
     2341 aagcccaggc agatcgaggt gagcattgcc ggcttgcctg ccgcgttcga tggctatcgc
     2401 gtgctgcagc tgaccgacat ccatgccagc cgcctgctga ccggcgactg ggtgcgcagg
     2461 gtcgtggacg agagcaacgc actgacgccg gacctgatcg tgatcaccgg cgacctgatc
     2521 gatggcagcg tcgaggcccg ccgcgacgac gcgcggccgc tggctgacct gcatgcaccg
     2581 gacggcgtca tcgccatcac cggcaaccac gagtactacg cgcagtacca gtcgtggatg
     2641 caggcgttcc gcgcgctgca catgcaggtg ctggagaaca gccacctgca ggtgcggcgc
     2701 ggtgatgcgg cgctgaccat cgctggcgtc accgatccgg tggccgcacg ctacggcctg
     2761 ccgctgccgg acctgggtgc cgcgctggcc ggtgccgatc cgacggcacc cgtgatcctg
     2821 cttgatcatc gcccgcgcaa tgcacgcgaa gcggccgcgc gtggcgtgaa gctgcaattg
     2881 tccgggcaca cccacggcgg gcagatcatc ggcatggacc agctggtgaa gcgggccaac
     2941 ggtggctatg tctccggtcg ctacgacgtg gatggcatga ccctgtacgt gagcaatggt
     3001 gcaggcctgt gggcaggttt cccggcacgc atcggcgtgc gttcggaaat caccctgatc
     3061 accctgcgcc gcgcgccgtg acctcaggcg gggtcagatc cctttccctt gggggaacgg
     3121 gatctgaccc ctgacaaacc acatggaagg aaccatgtcc catccccgcg ccccgatgga
     3181 acgcctgatc cgagccaatg ccgatgagat caaccggctg cgccaggtga tccgcaatac
     3241 cgcgggcgcg cgctggcgtg ggccggagga tcgggagcgg cacgctgcgg cttgtgcaga
     3301 attccaccag aactacgcgc gtctggcgtt tccgggcggc tacgccaacg cgctgaaacg
     3361 gctggccgaa catgatccag atacgctgga tgtcgcgctg accttccttg aagtgcggcc
     3421 gtatttcttc cggtccggat acatgtggaa gacgttgctg aagcgcgtgc aacgggtatc
     3481 catgggggcg aagcaacacg cgcggctgca ggggatcctc gatgcctacg ctgcctatcg
     3541 cgccacacgt gacggctgat gggacagcat gatggggtca gaccgcccgc agcggcggcc
     3601 gcgcatgcgc gcttcggcga agcgcctgcg cccgcttggc gatccagcgc accacgaagg
     3661 cagtgaacag cagcgccgac ggcactgcat accagaagtt gccgggcacg cgcttgaagt
     3721 acgagtaggt gaacaccgcc gcgatgatcc acatgccggt cacgtgcagg cgacgccagg
     3781 ccgtgggtcc catgcgccgg gcgagccccc ggtgcgaggt gatggccagc gccaggatgg
     3841 cgatgtagcc caccgttccc gggaggttgg ccagcgccga gcgtgctggc cagaacgctg
     3901 ggttgaggat gccgaaactg gtgatggcga ctgcgtgcag caggtgcgag aacgcgaagg
     3961 acaggccgat gatgcgccgt tcgcgcagca ggaaacgagt gaacgggccg ggcagcaggc
     4021 tggcgaacga cgatgccgtg aacgccgcca ggaacagcag gaacgacgtg cgtgcagtga
     4081 cccggatcgc cgcgcggctg ccctcgacca cgtcgggctg cagggtgaac gccgccagtg
     4141 cgacggcgat caggaccaca gccatggtca cgaaaaggcg ccagccgtgc aggaaggaag
     4201 tgttggaagc agccatgatc aaacctcgaa tcagacaggg gtagtgctgg ccgctggccg
     4261 ctggccggca gtcgcagaac ccggccagcg tgaccagcac gccggccgcg catagttcgc
     4321 ccagcaaggg cgtggccacc acgcgcagtt cgtcggcggc cacgccatgc gcatcggcca
     4381 gtgcgttcag cgcgtcatcc acgtgggtac cgtcatcagc gaaggccgac agcagcgcat
     4441 acgccagtgg tgccagttcc tcgacctgca gctggtagtc cgccaggcgg cgcagcagca
     4501 gaagcgtcgg ctcgctggcg gcggcatcgt ccagcgcggc gtcctcatgc accggccacc
     4561 ggtagcccaa tacccgcacc agcggcgaca gcgccagcac atcgctgccc gccggcatgg
     4621 actgcaatga atgcccggca tcacgtgcct cgatgtgcag cgtctgctgc gtgctttcgt
     4681 agtgcgccag ttccgccgcc cagccgggca gcgcgaacgc atactgcaca gccagccacg
     4741 cagcgaactc gctggcgatc tgcgggaaca acggggtatg gcacacgtgg tgtgcgtagt
     4801 agtgctcgac caggctgcgc cagcgcgccc tgcccagctg cgcctgcagg cgcggcaggc
     4861 tgcctgccag caggctgtcc aggctgtcga tgcagaggcg gcggtagact gccagccgcc
     4921 gcgcgtcgat gccatcgggc gcgggcatag acgggtcgcg tacgtgatcg gcccagcgtt
     4981 gctgcagggt ggccagggag tcaaccatgg gccaccttcg gcagcagcac atcgacctgc
     5041 gcctggcgga tctgctcgac ctcggccagc aactctgcca ggggcgggaa gttgaagtcg
     5101 cgttcgagca gcgtggggcg cacgccaacc cgcgcataag ccgcgcgcaa cagcgcccag
     5161 accacacctt tcaccggcgc accgtgggta tcgatcttga agccatcgtc ttcatcgaag
     5221 tgacccgcta cgtgcagcga ggcgacacgg tgggacggca cgcgggccag gaattcgaag
     5281 gcgtcgtaac cgttgttgca ggcgtttacg aagacgttgt tgacgtccag cagcaggtcg
     5341 cagtcggctt cggcgagcac ggcgttgatg aagtcgatct cgctcatctc cgcatcgggc
     5401 accgcgtaat aggaaatgtt ctccaccgcg atgcgcctgc ccagcgtgtc ctgcacctgg
     5461 cggatgcggc ccgcggcgtg gtgcacggct tcgtcggtga acggcagcgg cagcaggtcg
     5521 tagacatggc cgccggcagt gcagtagctc aggtgttcgc tgtacagctg cacctggtgc
     5581 aggtcgagga agtcgcgcgt ctgtgccagc agggtgcggt ccagcggatc aggaccgccc
     5641 agcgacagcg acaggccatg gcaggtcagg gggtgacgtt cgctcaacct gcgcagcgct
     5701 gcaccgtgtg caccaccgac gccgatccag ttgtcgggcg caacttcgag gaagtcgatg
     5761 gcaccggccg gcatggccag cagttcgtcg atcaggccac ggcgcaggcc aagaccggcg
     5821 gcgtttgagg gcaggggcag ggacatggcg gatgctccag ggagagggcg ccgcctcgga
     5881 ggcggcgccg gttgaacgtc gatcaatcgg caacgcggga gaacagaccc ttcggcatcg
     5941 gcttgctgtt ggcggtgtag acgctgcgca ggtagtcgtg cgcttcctgc tcggtgatgt
     6001 agccatcgtg gtcggtgtcg atgcggtcga actcggcggc acgcttggcg gccacggcgt
     6061 tgaactcggc acgcgagacc ttgccgtcgt ggtcacgatc ggtgcgggca aacgaggcgt
     6121 cgccgcactt gccttcgcca cactggccct cggccacctt ggccttgccg gcgggcttgc
     6181 cggtggtggc cttgttggcc ccgcacttgc cttcaccgca cttgccttcg gcggcagcgc
     6241 tcatggccac cgcgctgatc gccagcggct ggatcgccgc ggcctggccg gccagcagca
     6301 ggccaccggc cagggcgatg ccgatggcac cgacgcgcgg caggcgggag gagagggtgg
     6361 tcttggtcga gacggacatg gtgatgactc cttgcgaaag cacgcggggc gtgcgggatg
     6421 gacgccgccg aagaggcgac ggaaagaggc gcgtgggaaa aggcagatca gatcaggcgc
     6481 tgcggcgacg acgcagcaga tggcccagca gcagcacacc gccgagcagg gcaccgccga
     6541 agccgatgcc gggcagcagc gcggcaaccg gcagcagcag ggcgatcagg ctgacgcccc
     6601 agcccaggcc gtcatcgccg acgggggcgt gtcgcgagcc ggccagcagt cggtccacgc
     6661 tgagtgcgcc accgccgttg aggatcagtg gcagcagcat ggccaggaac agcagcggca
     6721 gcttgaagtt gccgtagccc tggtcggtga tcgcatagcc ctgccagagc tcgcccaggc
     6781 cgttccattg gtcgggccag tgcacggcgg cgatggcgac caccgtcaat acccagaaga
     6841 cgtaggccac cgagcgcgtg gccaggccga gcagcagcat cactgcaccc accagttcca
     6901 gccaggtggc cagctgccag ttcaatgatg cgggcagggt ggagaacggg aacggaaagc
     6961 ggccttccag gtcggcgaac cagttctggc cgcccagctt ttcgcggccg gattcaaaga
     7021 actcccaggc cagcagggtg cgcagcgcca atggcgagag ccagcggccg acggcgtcca
     7081 agcggggggt atacacggaa gaggcggtgc tgatcatgtg gcgtcctgcg ggccagtggt
     7141 cgatggacgc catttcaggc ggcgcaggta tcggcaacgt gtgccgttgc ccggggtttt
     7201 gtcagcgact gtggccgcgg ccgaggtttc ctacagtcag atacaaagac gatgcgttga
     7261 tgcacatcgg ggcgttgcgc gcccgcgcgc ggggaacgat ttccacccgg tagtgcctgg
     7321 ccgggcgcgg cgcccgaatg tatcccactg tagaaacacg cctgcgccct acagtccggt
     7381 acaactccgt gctgcggaga aacagcaccg atacaccggc aggcggaaat ggccgctccc
     7441 aacaccggag tgccacccat gatccgtacc tcgttgcttg ccgctgctct cgcccttgcc
     7501 ggcgccgccg ctcccgcctt cgctacccag gccgataccg ctgcaccgcc caccgtcatc
     7561 ctggtgcacg gcgccttcgc cgatggctcc agctggaaca gggtcatcag caccctgcat
     7621 gactggaagc tgccggtggt ggccgtgcag aatccgctca cctcgttggc cgacgacgtc
     7681 gccgccaccc gtcgcgccat tgccgccgcg cccggcaggg tggtgctggt cggccacagc
     7741 tggggcggta cggtcatcac cgaggcgggc gatgacccga aggtgcaggc gctggtgtac
     7801 gtggcggcct tcgcaccgga tgcagggcag tcttcggcgc aacagggcga aggtttcccg
     7861 gtcggtccgg gcctggcccg attgcaggaa agggatggct acctgacgtt gcccgctgat
     7921 gccatcgccc aggacttcgc gccggacgtg atgaagaagt cggccgcact gctgtacagc
     7981 acgcaggtcc cgttgaaggc cagcgcgctg ggcgaggtgg tgaacgttgc ggcctggcgc
     8041 agcaagccga gctggtacgt gctcagccgc gacgatcgca tgctgtcgcc gcagctgcag
     8101 gccgccaccg caaagcgcat tggtgcgcag ctgcaatcga tcggcagcag ccacgtgtcg
     8161 ctgctttcgc atccggcgca ggtggccgac agcatcctgg aggcggcagg cgtgaagccg
     8221 gccgaattgc cgctggccga gcaggggggc tgagcgatgg ccgcgctacg agggtatgca
     8281 ctgcccctgc tgctgggcct gctgggtgga gcggtgttgc tgctggcatg gcccggtgcc
     8341 gaggccggcg cgcagccgct cgacgcagca ccgaaggcgg ggttcggcgg tggcgggccc
     8401 tggcgcaaca gcccaccgat tacactgaag cagttgcggg ggcaggtggt actggtcgag
     8461 ttctggacct acacctgcag caactgcctc aatgtggcgc cgtatgttca ccagtggcat
     8521 gcacgctacg cgtcgcaggg cctgcaggtg atcggcgtgc atacgccgga gttcgcctat
     8581 gagggcgtgc ccggcaacgt gcgcagggcc atcggccgct tggacatcac ctggccggtg
     8641 gtgcaggaca accagttccg gatctggaac gcctggggca atcgcttctg gccggcactg
     8701 tacctgctcg accggcaggg gcgggtggtc tatcgccatt acggcgaggg cgactacgca
     8761 cgtaccgaaa gcgagatcca gcgcctgctg gccagcccct gagccgcgct accatggccg
     8821 cgccgcgcgg cgctgccccc tgccttcatc gagaacgcaa tgaatcctgt accgcacatc
     8881 cttgtcgtcg acgatgacag tgagatccgc cagatgctgg ccgactacct gcaacgcaac
     8941 ggcctgcgcg tgagccaggc cgacggtggc cgggccatgc gcgcactgat ggatacccac
     9001 gcggtggacc tggtggtgct ggacgtgatg atgccgggcg aagacggcct gagcctgtgc
     9061 cgcaacctgc gtgccggcaa gcatcgtgcg gtgccggtgg tgctgctgac cgcacgcgac
     9121 gacgagaccg accgcatcat cggcctggaa atgggcgccg acgactacgt gaccaagccg
     9181 ttctcttccc gcgaactgct ggcacgcatc aatgcggtga tccgtcgcac ccggatgctg
     9241 ccgccgaacc tacaggtgag cgaagccggt cgccaactgg ccttcggtgc ctggcgcctg
     9301 gataccaccg cgcgccatct gctggatgca caggacaccg cgtatccgct cagtggtgcc
     9361 gagttccgcc tgttgcgcgt gttcctcgat cacgccaatc gcgtgctcag ccgtgaccag
     9421 ctgctcagcc tcacccaggg ccgcgatgcc gaactgttcg accgctcgat cgacctgctg
     9481 gtcagccgcg tgcggcagcg cctgggtgac gacgcacgcg agccgaccta catcaagacc
     9541 gtgcgcagcg aaggctatgt gttcagcgtg ccggtgcagt tgctggggcc ggacgaatga
     9601 acaccggcgc acgccgtcca cgctggccgc gcacgctgtc ggcgcggctg ctgctggtgc
     9661 tgctgggcgg actggcgctg gcccacgcgc tgtccttcgg cctgctgttc ttcgaacgct
     9721 accaatccac ccgcagcatg atgctgcgca acctggatga agacgtggca gtaagtgtcg
     9781 cgctgctgga gcacctgccc gcagagcagc gcgatgcctg ggtgccgcgg ctggagcggc
     9841 gcacctaccg ctacctgttg cgcccggcta cggccgggcc cgggctgcag accgatcgtg
     9901 cacgccaggt cactgcgatc atcgacgaca gcctgcagca ccgctatccc ttgcaggcgc
     9961 gccaggtggc tcgcctgccg gagcggttcg aggtggaact gcgcctgcac gacggcacgc
    10021 cgttgaccat tgaagtcacc ccgtcgggcc tgccgctggc acgctggctg cccgccgtac
    10081 tgcttgtgca gctggcgctg ctgctggtgt gcgcatggct ggcagtgcgc ctggccatgc
    10141 gcccgttgca gcggctgtcg catgcggtgg aacagctgca gccgggcaac gacggaccgg
    10201 cactgcctga agatggccct gtggaagtgg gcggtgcggc ggccgcactc aacgcgctgc
    10261 aggcacgcat tcgtggccat gtcagtgagc gcctgcagat ccttgcagcg atctcgcacg
    10321 atctgcagac ccccatcaca cgcatgaagc tgcgggtgga gacgctgcct gaagacagca
    10381 cccagcagcg gctgatggcc gatctcgaac accttgggca actggtgcga gagggtgtgg
    10441 cctatgcgcg cagcagccac gtcgccagtg gtgcgccggt gtcgatggac ctgggtgcgt
    10501 tcctggccag tgtggtcggc gactacgagg acatgggcaa gccggtcagt ggcggtgcgc
    10561 ccgccggact gatcgtgcag acctggccgc agccgctgcg acgggtggtc ggcaacctgg
    10621 tcgacaacgc attgcgctac gccggtgccg ccgagatcga agccggccgt gatgaggctg
    10681 gcaggatatg gatccgtatt tccgaccgtg gcccgggtat cccggagaac cagctgcagg
    10741 cggtgctggc accgttccat cggctggaaa gctcgcgcaa ccgcgatacc ggcggcaccg
    10801 gcctgggcct gtccatcgcg gtgcagctgg cgcagtcgct gggcgg
//
