LOCUS       NZ_CP040435            10846 bp    DNA     circular CON 07-MAY-2024
DEFINITION  Stenotrophomonas maltophilia strain PEG-42 chromosome, complete
            genome.
ACCESSION   NZ_CP040435
VERSION     NZ_CP040435.1
KEYWORDS    RefSeq.
SOURCE      Stenotrophomonas maltophilia
  ORGANISM  Stenotrophomonas maltophilia
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Stenotrophomonas; Stenotrophomonas maltophilia
            group.
REFERENCE   1  (bases 1 to 4854802)
  AUTHORS   Gonzaga,A. and Nubel,U.
  TITLE     Stenotrophomonas maltophilia genomes
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4854802)
  AUTHORS   Gonzaga,A. and Nubel,U.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-MAY-2019) Mikrobielle Genomforschung, Leibniz-Institut
            DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH,
            Inhoffenstrasse 7 B, Braunschweig 38124, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. v3.12.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150X
            Sequencing Technology             :: PacBIO + Illumina Miseq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009676525.1-RS_2024_05_06
            Annotation Date                   :: 05/06/2024 04:38:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,515
            CDSs (total)                      :: 4,425
            Genes (coding)                    :: 4,399
            CDSs (with protein)               :: 4,399
            Genes (RNA)                       :: 90
            rRNAs                             :: 5, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 26
            CDSs (without protein)            :: 26
            Pseudo Genes (ambiguous residues) :: 0 of 26
            Pseudo Genes (frameshifted)       :: 10 of 26
            Pseudo Genes (incomplete)         :: 16 of 26
            Pseudo Genes (internal stop)      :: 2 of 26
            Pseudo Genes (multiple problems)  :: 2 of 26
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:43:42
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1228560
            Orig. end                         :: 1239406
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP040435.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..10846
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10846
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10846
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5846](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5846)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            461..685
                     /locus_tag="FEO92_RS05725"
                     /old_locus_tag="FEO92_05795"
     CDS             461..685
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012479411.1"
                     /locus_tag="FEO92_RS05725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO92_05795"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_154348666.1"
                     /transl_table=11
                     /translation="MAIVITLDRMLQQRGMTLSELAGRIDITLANLSILKTGKARAIRF
                     STLDAICRELQCTPGELLGHDPTQAQDAD"
     gene            729..2267
                     /locus_tag="FEO92_RS05730"
                     /old_locus_tag="FEO92_05800"
     CDS             729..2267
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1273: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005408495.1"
                     /locus_tag="FEO92_RS05730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO92_05800"
                     /product="TerC family protein"
                     /protein_id="WP_154348667.1"
                     /transl_table=11
                     /translation="MEWLADPSIWMGLATLVVLEIVLGIDNLVFIAILADKLPPHQRDR
                     ARVIGLALALLMRLVLLAALAWIMKLTEPLLTLFDHSFSGRDLILLGGGLFLLFKGTME
                     LHERLEGREHHEDGKKVYASFAMVVVQIVVLDAVFSLDSVITAVGMVDNLGVMYAAVTI
                     AMALMLLASKPLTRFVNKHPTVVVLCLGFLLMIGFSLVAEGLGYKIPKGYLYAAIAFSI
                     LVEAFNQWVRFNRERNERRQPFRQRTADAVLRMLGARPANGHDDEAADEHVDAEERLQP
                     AEHEMIRSVLGLADRPVSSVMTVRADVQWIDLARGQEDVVARLVASPHTRLLVGDGDLD
                     SLRGVVQSRDLLADLLQGKPLQLEGNLREPQYVLSSASALQALELIRQHPVPLAVAVDE
                     YGSVEGLVTANDLLAAIAGDLVDTQDERYGVVAQGEDCWEADGALTLDDLQRLAGISLP
                     RSADYMTISGLVLERLGRLPDIGDAVEIAEVRITVLAMEKRRIARLRVERLGHL"
     gene            2402..3538
                     /locus_tag="FEO92_RS05735"
                     /old_locus_tag="FEO92_05805"
     CDS             2402..3538
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004147841.1"
                     /locus_tag="FEO92_RS05735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO92_05805"
                     /product="metallophosphoesterase"
                     /protein_id="WP_154348668.1"
                     /sec_met_domain="Metallophos_2 (E-value: 1.8e-08, bitscore:
                     32.6, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVAVLSTIGLLMGLYVAWRLFWPLRMPIWMKVVLSLLLVGVAVQL
                     RIVATFWGTTASPEIPKLAIATLAAGSTAVLLLALLMLALDVGLLASRLLRWPRAVAAL
                     RTRSLRPAAALLALLVSGYGVSQGMVVPKPRQIEVSIAGLPAAFDGYRVLQLTDIHASR
                     LLTGDWVRRVVDESNALTPDLIVITGDLIDGSVEARRDDARPLADLRAPDGVVAITGNH
                     EYYAQYRAWMQAFRALHMQVLENSHLQVRRGDAALTIAGVTDPVAARYGLPLPDLEAAL
                     AGADPSAPVILLDHRPRNAREAAARGVKLQLSGHTHGGQIIGMDQLVKRANDGYVSGRY
                     EVDGMTLYVSNGAGLWAGFPARIGAPSEITLVTLRGAP"
     gene            complement(3551..4222)
                     /locus_tag="FEO92_RS05740"
                     /old_locus_tag="FEO92_05810"
     CDS             complement(3551..4222)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646319.1"
                     /locus_tag="FEO92_RS05740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO92_05810"
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="WP_154348669.1"
                     /transl_table=11
                     /translation="MAPSNTSFLHGWRLFVAVAAVLIAFALAAFALHADVAEGSRAAIR
                     VTARTSFLLFLAAFTASSFASLLPGPFTRLLLRERRVIGLSFAFSHLLHAIAITSFGIL
                     NPAFWPARSALANLPGTVGYIAILALAITSHRGLARRMGPTAWRRLHVTGMWTIAAVFT
                     YSYFKRVPGNFWYAVPSALLFTAFVVRWIAKRAQALRRSAHACPAQLGTESEPFAGGKG
                     I"
     gene            complement(4274..5008)
                     /locus_tag="FEO92_RS05745"
                     /old_locus_tag="FEO92_05815"
     CDS             complement(4274..5008)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646320.1"
                     /locus_tag="FEO92_RS05745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO92_05815"
                     /product="putative DNA-binding domain-containing protein"
                     /protein_id="WP_154348670.1"
                     /transl_table=11
                     /translation="MSESLATLQRRWADHVRDPSMPAPDGVEARRMAVYRRLCIDSLDS
                     LLAGSLPRLKSQLGDACWRDTVEHYYASHACHTPLFPRIAGEFAGWLAVQDTLALPAWA
                     AEMAHYESTQQSLHIEARDAGPPLHRVPAGIDVLAVSPWVRVLGYQWPVHEEDVLEPVS
                     SAAPTLLVIQRLVDSSLQVEELSPLAYALLSVFGDDGAPVDEALQVLSETHGVATDALR
                     MACAPVLDELCTAGVLVAWPAF"
     gene            complement(5001..5846)
                     /locus_tag="FEO92_RS05750"
                     /old_locus_tag="FEO92_05820"
     CDS             complement(5001..5846)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646321.1"
                     /locus_tag="FEO92_RS05750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO92_05820"
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_154348671.1"
                     /sec_met_domain="DUF692 (E-value: 4.1e-119, bitscore:
                     394.8, seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLPLPFNAAGLGLRRGLIDELLAMPAGAIDFLEVSPDNWIGVGG
                     AHGAALRQLSERHPLTCHGLSLSLGGPDPLDRTLLAQTRAFLDVHQVQLYSEHLSYCAA
                     GGHLYDLLPLPFTAEAVHHVAGRIAQVQDVLGRRIAVENISYYAVAGADLSEIDFINAV
                     LAEADCDLLLDVNNVFVNACNNGYDAFEFLARVPSHRVASLHVAGHFDEDDGFKIDTHG
                     APVKSVVWALLREAYARVGVRPTLLERDFNFPPLAELLGEVAQIRQAQAEARLPEVAHV
                     "
     misc_feature    5878..5887
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     gene            complement(5903..6379)
                     /locus_tag="FEO92_RS05755"
                     /old_locus_tag="FEO92_05825"
     CDS             complement(5903..6379)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005412584.1"
                     /locus_tag="FEO92_RS05755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO92_05825"
                     /product="EF-hand domain-containing protein"
                     /protein_id="WP_154348672.1"
                     /transl_table=11
                     /translation="MSVSTKNTPSSRLPRIGAIGIALAGGLLLAGQGAAIQPLAISAVA
                     MSAAAEGKCGEGKCGANKATTGKPAGKAKVAEGQCGEGKCGDASFARTDRDRDGKVSRA
                     EFNAVAAKRAAEFDRIDTDHDGYISEQEAHDYLRSVYTANGKPMPKGLFSRVAD"
     gene            complement(6475..7119)
                     /locus_tag="FEO92_RS05760"
                     /old_locus_tag="FEO92_05830"
     CDS             complement(6475..7119)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012479418.1"
                     /locus_tag="FEO92_RS05760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO92_05830"
                     /product="DoxX family protein"
                     /protein_id="WP_154348673.1"
                     /transl_table=11
                     /translation="MISIASSVYTPRLDAVGRWLSPLALRTLLAWEFFESGREKLGGQN
                     WFADLEGRFPFPFSTLPASLNWQLATWLELVGAVMLLLGLATRSVAYIFWVLTVVAIAA
                     VHWPDQWNGLGELWQGYAITDQGYGNFKLPLLFLAMLLPLILNGGGALSVDRLLAGTPH
                     APAGNDGLGWGVSLIALLLPVAALLPGIGFGGALLGGVLLLGHRLRRRRAA"
     misc_feature    complement(7223..7241)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.64"
                     /tool="antismash"
     gene            7461..8261
                     /locus_tag="FEO92_RS05765"
                     /old_locus_tag="FEO92_05835"
     CDS             7461..8261
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005408502.1"
                     /locus_tag="FEO92_RS05765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO92_05835"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_154348674.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.2e-14, bitscore:
                     53.5, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTSLLAAALAVAGAAAPAPAFAARADTAAPPTVILVHGAFADG
                     SSWSKVISTLHDWKLPAVAVQNPLTSLADDVAATRRAIAAAPGKVVLVGHSWGGTVITE
                     AGNDPKVQALVYVAAFAPDAGQSSAQQGEGFPVGPGLARLQERDGYLTLPADAIAQDFA
                     PDVMKKSAALLYSTQVPLKASALGEVVNVAAWRSKPSWYVLSRDDRMLSPQLQAATARR
                     IGAQLQSVGSSHVSLLSHPAQVADSILEAAGVKPAELPLAEQGG"
     gene            8265..8810
                     /locus_tag="FEO92_RS05770"
                     /old_locus_tag="FEO92_05840"
     CDS             8265..8810
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1241: lipoprotein
                     dsbF"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005415663.1"
                     /locus_tag="FEO92_RS05770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO92_05840"
                     /product="redoxin family protein"
                     /protein_id="WP_107379270.1"
                     /transl_table=11
                     /translation="MAALRGYALPLLLGLLGGAALLLAWPGADAGAQPHDAVPMAGFNG
                     GGPWHNSPPLTLTQLRGQVVLVEFWTYTCSNCLNVAPYVHQWHARYAPQGLRVIGVHTP
                     EFAYEGLPGNVRKAIARLDITWPVVQDNQYRIWNAWGNRFWPALYLLDRQGRVVYRHYG
                     EGDYARTESEIRRLLANP"
     gene            8869..9609
                     /locus_tag="FEO92_RS05775"
                     /old_locus_tag="FEO92_05845"
     CDS             8869..9609
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019659345.1"
                     /locus_tag="FEO92_RS05775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FEO92_05845"
                     /product="response regulator"
                     /protein_id="WP_154348675.1"
                     /transl_table=11
                     /translation="MNHVPHILVVDDDSEIRQMLADYLQRNGLRVSQADGGRAMRALMD
                     THAVDLVVLDVMMPGEDGLSLCRNLRAGKHRAVPVVLLTARDDETDRIIGLEMGADDYV
                     TKPFSSRELLARINAVIRRTRMLPPNLQVSEAGRQLAFGEWRLDTTARHLLDAQDTAHP
                     LSGAEFRLLRVFLDHANRVLSRDQLLSLTQGRDAELFDRSIDLLVSRVRQRLGDDAREP
                     TYIKTVRSEGYVFSVPVQLLGPDE"
     misc_feature    complement(10405..10419)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
ORIGIN
        1 gccgcactgc tggccgtgcc actggtcgcc cacgaccgcc gttggctgct cgacagcgtg
       61 cacgacgcgc aggccgcggc cgtgcacggt tcgcatctgt tcctgcattt ctgcgtgggc
      121 ctggccgcca tcgtcgcact actggtgctg tgcctgatgt tcctgcgcca cctggcgcgg
      181 ctgctgcgtt ctgcggccaa cgaacgcccc ttcacccatg ccaatgccgt acgcctgcaa
      241 cgcatggcct ggctgatgct ggcgatggag gtgctgtcca tcgtgatcgg tctgtacgcc
      301 agctggatgg ggccggactt tgcgtggatg gaagttggcg gtggcatgtc gatcaccggc
      361 ctggtggccg tactgatgct gttcgtactg gcgcgggtgt tcaccgttgg cgcagcgatg
      421 cgcgacgatc tggacggtgt gatttgatga gcatgatctg atggcgatcg tcatcaccct
      481 cgaccgcatg ctgcagcagc gcggcatgac cttgtccgag ctggccgggc gcatcgacat
      541 cactctggcc aacctgtcga tcctgaaaac cggcaaggcg cgcgccatcc gcttttccac
      601 actcgatgcg atctgccgtg agctgcagtg cacgcccggt gagctgctcg ggcatgaccc
      661 gacccaggcg caggacgctg actgagtgct ttcccttttc ccttacctac tgacgaaacg
      721 gacctgaaat ggaatggttg gctgacccct cgatatggat gggccttgca accctggtcg
      781 tgctggagat cgttctcggc atcgacaacc tggtgttcat cgcgatcctt gccgacaaac
      841 tgccgccgca ccagcgtgac cgcgcgcggg tgatcggcct ggcgctggcc ctgctgatgc
      901 ggctggtgct gctggccgcg ctggcctgga tcatgaaact gaccgagcca ctgctgacgc
      961 tgttcgacca cagcttctcc gggcgtgacc tgatcctgct gggcggtggc ctgttcctgc
     1021 tgttcaaggg caccatggag ctgcacgaac ggctggaagg ccgcgagcac cacgaggatg
     1081 gcaagaaggt ctatgccagc ttcgcgatgg tcgtggtgca gatcgtggtg ctcgatgcgg
     1141 tgttctcgct ggactcggtg atcaccgcgg tgggcatggt cgacaacctg ggcgtgatgt
     1201 atgccgcagt gaccattgcg atggcgctca tgcttttggc cagcaagccg ctgacccgct
     1261 tcgtcaacaa gcatcccacg gtggtggtgc tgtgcctggg cttcctgctg atgatcggtt
     1321 tcagcctggt ggccgaaggc ctgggctaca agattccgaa gggctacctg tacgcggcga
     1381 tcgccttctc gatcctggtc gaagcattca accagtgggt gcgcttcaac cgtgagcgca
     1441 acgagcgccg ccagccgttc cggcagcgca cggccgatgc cgtgctgcgc atgctgggtg
     1501 cgcgcccggc caatggccac gacgacgaag ccgcagacga acacgtcgat gccgaagagc
     1561 gcctgcagcc ggcggagcac gagatgatcc gcagcgtgct gggcctggcc gatcgcccgg
     1621 tgtcgagcgt gatgaccgtg cgtgccgacg tgcagtggat cgacctggcg cgtgggcagg
     1681 aggatgtggt ggcccgcctg gtggcgtcgc cgcatacccg cctgctggtg ggcgacggtg
     1741 atctggacag cctgcgtggc gtggtgcaga gccgcgacct gctggccgat ctgctgcagg
     1801 gcaagccgct gcagctggaa ggcaacctgc gcgagccgca gtacgtgctg tccagcgcca
     1861 gtgcgctgca ggcgctggag ctgatccgcc agcatccggt gccgttggcg gtggcggtgg
     1921 acgagtacgg cagcgtggaa ggcctggtga ccgccaacga cctgctggcg gccattgccg
     1981 gtgacctggt cgacacccag gacgaacgct atggcgtggt cgcccagggt gaagattgct
     2041 gggaggccga tggcgcgctg accctggacg acctgcagcg cctggcgggt atatcgctgc
     2101 cgcgcagtgc cgactacatg accatctccg gtctggtgct cgagcgcctg gggcgcctgc
     2161 cggacattgg tgatgcggtg gagattgcgg aagtacgcat caccgtactg gcgatggaga
     2221 agcggcgcat cgcccgcctg cgggttgaac gcctgggcca tctgtagcgt cgagccctgc
     2281 tcgactgggg ttctgtagcg ttgagccatg ctcgactgct tcctgagcag ccgagcacgg
     2341 gctcggctct acacaacatc tcccgcaacc gtcaccatgg cgggcccgct ttctttcccg
     2401 gatggttgca gtgctgagta cgatcggttt gttgatgggc ctctatgtgg cctggcgcct
     2461 gttctggcca ctgcgcatgc ccatctggat gaaggtcgtg ctgtcgctgc tgctggtggg
     2521 cgttgccgtg cagttgcgca tcgtcgccac cttctggggc acgacggcct cgccggagat
     2581 accgaagctg gccatcgcca cgctggccgc cggctccacg gcggtgttgc tgttggcgtt
     2641 gctgatgctg gcgctggatg tgggtctgct cgcctcccgc ctcctgcgct ggccacgcgc
     2701 ggtagccgcg ttgcgcacgc ggagtctgcg gccggcggcc gccctgctgg ccctgttggt
     2761 cagtggctac ggcgtcagcc agggaatggt ggtacccaaa ccccggcaga tcgaggtgag
     2821 cattgccggc ttgcctgccg cgttcgatgg ctatcgcgtg ctgcagttga ccgacatcca
     2881 cgccagccgc ctgctgaccg gcgactgggt gcgcagggta gtggatgaga gcaacgcact
     2941 gacgccggac ctgatcgtga tcaccggcga cctgatcgac ggcagtgtcg aggcccgccg
     3001 tgacgacgcg cgcccactcg cggacctgcg ggcgccggac ggtgtcgtcg ccatcaccgg
     3061 caaccacgag tactacgcgc agtaccgggc gtggatgcag gcgttccgcg cgctgcacat
     3121 gcaggtgctg gagaacagtc atctgcaggt gcggcgcggc gatgcggcgc tgaccatcgc
     3181 cggtgtcacc gatccggtgg ccgcgcgcta cggcctgccg ctgccggatc tggaggccgc
     3241 gttggccggt gccgatccgt ccgcgccggt gatcctgctt gatcatcgcc cgcgcaatgc
     3301 gcgcgaggcg gcggcgcgtg gggtgaagct gcagctgtcc gggcataccc acggcgggca
     3361 gatcatcggc atggaccagt tggtgaagcg ggccaacgat ggctatgtct ccgggcgtta
     3421 tgaagtggac ggcatgaccc tgtacgtgag caacggtgca gggctgtggg ccggtttccc
     3481 ggcgcgcatc ggcgctccat cggagattac cctggtgacg ttgcgcggcg cgccgtgatc
     3541 tctactgggg tcagatccct ttgccaccgg cgaagggctc tgactctgtg cccaactgcg
     3601 cggggcacgc atgcgcactt cgacgcagcg cctgcgcccg cttggcgatc cagcgcacca
     3661 cgaaggcggt gaacagcagc gccgacggca ccgcatacca gaagttgccc ggcacgcgct
     3721 tgaagtacga gtaggtaaac accgccgcga tggtccacat gccggtgacg tgcaggcgac
     3781 gccaggcggt gggtcccatg cgccgggcga gcccccggtg cgaggtgatg gccagcgcca
     3841 ggatggcgat gtagcccact gtgcccggga ggtttgccag cgcggatcgt gctggccaga
     3901 acgccgggtt gaggatgccg aaactggtga tggcaattgc atgcagcagg tgcgagaacg
     3961 cgaacgacag gccgatgacg cgccgttcgc gcagcagcaa ccgggtgaac gggccgggca
     4021 gaaggctggc gaacgacgat gccgtgaacg ctgccaggaa cagcaggaac gatgtgcgcg
     4081 cagtgacccg gatcgccgct cggctgccct cggccacatc ggcatgcagg gcgaacgcgg
     4141 ccagcgcgaa ggcgatcagt accgccgcga cggccacgaa caggcgccag ccgtgcagga
     4201 aggaagtgtt ggatggagcc atgatgagac ctcggagtag ggggacggta gtgccggccg
     4261 ctggctggca acttcagaaa gcaggccacg cgaccagcac gcctgccgtg cacagttcgt
     4321 ccagaacggg cgcgcaggcc atgcgcagtg catccgttgc cacgccatgt gtttcggaca
     4381 gcacctgcag tgcctcatcc acaggcgcgc cgtcgtcgcc gaacaccgat agcagcgcgt
     4441 aggcaagcgg tgacagttcc tcgacctgca ggctggaatc gacgaggcgc tggatcacca
     4501 gcagcgtggg agctgcgctc gataccggct ccagcacatc ttcctcatgt accggccact
     4561 ggtagccaag cacccgcacc cacggcgaaa ccgccagcac atcgatgccc gcgggaacgc
     4621 ggtgcagcgg cggcccggcg tcacgcgctt caatatgcag cgactgctgc gtgctctcgt
     4681 agtgggccat ttccgctgcc caggccggca gcgccagcgt gtcctgcacc gccagccagc
     4741 ccgcgaactc gccggcgatc cgtgggaaca gcggggtgtg acaggcgtgg ctggcgtagt
     4801 agtgctccac tgtgtcgcgc cagcaggcat cgcccagctg cgacttcaac cgcggcaggc
     4861 tgcccgccag caggctgtcc agactgtcaa tgcacaggcg gcggtagacc gccatccgcc
     4921 gtgcctcgac gccatcgggc gcaggcatcg acgggtcccg cacatgatcg gcccagcgcc
     4981 gttgcagggt agccagcgac tcagacatgg gccacctcgg gcaaacgtgc ctcggcctgc
     5041 gcctggcgga tctgcgcaac ctcgcccagc agttctgcaa gcggcgggaa gttgaagtcg
     5101 cgttcgagca gcgtggggcg tacgcccacc cgcgcatagg cctcgcgcaa cagcgcccag
     5161 accacacttt tcaccggcgc gccgtgggtg tcgatcttga agccatcgtc ttcatcgaag
     5221 tggcccgcca cgtgcagcga ggcgacacgg tgggacggca cgcgggccag gaattcgaag
     5281 gcgtcgtaac cgttgttgca ggcgttgacg aagacgttgt tgacgtccag cagcaggtcg
     5341 cagtcggctt cggcgagcac ggcgttgatg aagtcgatct cgctcaagtc cgcgccggca
     5401 acggcgtagt aggagatgtt ctccaccgcg atgcgccggc ccagcacgtc ctgtacctgg
     5461 gcgatgcggc cggccacatg gtgtacggcc tcggcggtga acggcagtgg cagcagatcg
     5521 tagagatggc caccggcggc gcagtagctc aggtgttcgc tgtacagctg cacctggtgc
     5581 acgtcgagga aggcacgggt ctgtgccagc agggtgcggt ccagtggatc aggaccgccc
     5641 agcgacagtg acagtccgtg gcaggtcaag gggtggcgct cgctgagttg gcgcagcgcg
     5701 gcgccgtgtg caccgccgac gccgatccag ttgtcggggg agacttcgag gaagtcgatg
     5761 gcaccggccg gcattgccag cagttcgtcg atcaggccac ggcgcaggcc aagaccggcg
     5821 gcattgaaag gcaggggcag ggacatggcg gatgctccag agggagggcg ccgcctcgaa
     5881 ggcggcgccg ggtgaacgtc gatcaatcgg cgactcggga gaacaggccc tttggcatcg
     5941 gcttgccgtt ggcggtgtaa acgctgcgca ggtagtcgtg cgcttcctgc tcgctgatgt
     6001 agccgtcgtg atcggtgtcg atgcggtcga actcggcggc acgcttggcg gccacagcgt
     6061 tgaactcggc gcgcgagacc ttgccgtcgc ggtcacggtc ggtgcgggca aacgaggcgt
     6121 cgccgcactt gccttcgcca cactggccct cggccacctt ggccttgcca gcgggcttgc
     6181 cggtggtggc cttgttggcc ccgcacttgc cttcaccgca cttaccttcg gcggcggcgc
     6241 tcatggccac cgcgctgatc gccagcggtt ggatcgcggc gccctggccg gccagcagca
     6301 ggccaccggc cagggcgatg ccgatggcac cgatgcgcgg caggcgggag gagggggtgt
     6361 tcttggtcga gacggacatg gtggtgactc cttgggaaag cacgcggggc gtgcgggatg
     6421 gacgccgccg aagaggcgac ggaaagcgaa acgcgcgggt acaggggaat cagctcaggc
     6481 ggcgcggcgg cgacgcagcc gatggcccag cagcagcaca ccgccgagca gggcaccgcc
     6541 gaagccgatg ccgggcagca gcgcggcaac cggcagcagc agggcgatca ggctcacacc
     6601 ccagcccagg ccgtcattgc cggcgggggc atgcggcgtg ccggccagca gccggtccac
     6661 gctgagcgcg ccaccgccgt tgaggatcaa tggcagcagc atggccagga acagcagcgg
     6721 cagtttgaag ttgccgtagc cctggtcggt gatcgcatag ccctgccaga gttcacccag
     6781 gccgttccat tggtcgggcc agtgcacggc ggcgatggcg accacggtca acacccagaa
     6841 gatgtaggcc accgagcgcg tcgccaggcc aagcagcagc atcaccgcgc ccaccagttc
     6901 cagccaggtg gccagctgcc agttcagcga cgcgggcagg gtggagaacg ggaacggaaa
     6961 gcggccttcc agatcggcga accagttctg gccgcccagc ttctcgcggc cggattcaaa
     7021 gaactcccag gccagcaggg tgcgcagcgc caggggtgac agccagcggc cgacggcatc
     7081 caggcggggg gtatacacgg aagaggcgat gctgatcatg gtggtgtcct gcgggccagt
     7141 ggtcgatgaa ggccattcca ggcggcgcag gtatcggcaa cgtgtgccgt tgcctggggt
     7201 tttgtcagcg actgtggtcg cggccggggt ttcgtacagt cagatacaaa gacgatgcgt
     7261 tgatgcacat cgggcgttgc gcgcccgcat gcggggagcg atatccaccc ggcagcgccc
     7321 agccaggacc ggcgcccgaa tgtatcccac tgtagaaacc cgcccgcgct ctacagtccg
     7381 gtacaactcc gcgctacgga gaaacagcgg cgatacaccg gcaggcggaa atggctactc
     7441 ccaacaccgg agtgtcaccc atgatccgta cctcgctgct tgccgccgcg ctcgccgttg
     7501 ccggcgccgc cgcccccgcc cccgccttcg ctgcccgggc cgatactgct gcaccgccca
     7561 ccgtcatcct ggtgcacggc gccttcgccg atggctccag ctggagcaag gtcatcagca
     7621 ccctgcacga ctggaagctg ccggcggtgg ccgtacagaa tccgctcacc tcgttggccg
     7681 acgacgtcgc cgccacccgc cgcgcgattg ccgccgcgcc cggcaaggtg gtgctggtcg
     7741 gccatagctg gggtggcacg gtcatcaccg aagcgggcaa tgacccgaaa gtacaggcgc
     7801 tggtgtacgt ggccgccttc gcgccggatg ccgggcaatc ttcggcgcaa cagggcgaag
     7861 gtttcccggt tggtccgggc ctggcccgac tgcaggaaag ggatggctac ctgaccttgc
     7921 cggcggatgc catcgcccag gacttcgcgc cggacgtgat gaaaaagtcg gccgcactgc
     7981 tgtacagcac gcaggtcccg ttgaaggcca gcgcgctggg cgaggtggtg aacgtggcgg
     8041 cgtggcgcag caagccgagc tggtacgtgc tcagccgcga tgaccgcatg ctgtcgccgc
     8101 agctgcaggc cgcgaccgca cgtcgcattg gtgcacaact gcaatcggtc ggcagcagcc
     8161 atgtctcgct gctttcgcat ccagcgcagg tggccgacag catcctggaa gcagcggggg
     8221 tgaagccggc ggaactgccg ctggccgagc agggtggctg agcgatggcc gcactgcgag
     8281 ggtacgcatt gccgctgttg ttgggcctgc tgggcggagc ggcgttgttg ctggcatggc
     8341 ccggtgcgga tgccggcgcg cagccgcacg atgcagtacc gatggcgggg ttcaacggtg
     8401 gcgggccctg gcacaacagc ccaccgctca cgctgacgca gttgcggggg caggtggtgc
     8461 tggttgagtt ctggacctac acctgcagca actgcctcaa cgttgcgccg tatgtccacc
     8521 agtggcatgc acggtacgcg ccgcaggggc tgcgggtgat cggcgtgcat acgccggagt
     8581 tcgcctatga agggctgcct ggcaacgtgc gcaaggccat cgcacggttg gatatcacct
     8641 ggccggtggt gcaggacaac cagtaccgga tctggaatgc ctggggcaac cgcttctggc
     8701 ccgcgctgta cctgctcgac cggcaggggc gtgtggtcta ccgtcattac ggcgagggcg
     8761 actacgcacg taccgaaagc gagatccggc gcctgctggc caacccctga gccgcgctac
     8821 catggccgcg ccgcgcggcg ctgtccccct gccttcatcg agaacgcaat gaaccacgta
     8881 ccgcatatcc tggtcgtcga cgatgacagc gagatccgcc agatgctggc tgactacctg
     8941 caacgcaacg gcctgcgcgt gagccaggcc gacggtggcc gggcgatgcg cgcgctgatg
     9001 gatacccatg ccgtggatct ggtggtgctg gacgtgatga tgccgggcga ggatggactg
     9061 agcctgtgcc gcaacctgcg cgccggcaag catcgtgcgg tgccggtggt gctgctgact
     9121 gcccgcgacg acgagaccga tcgcatcatc ggcctggaaa tgggtgctga cgactacgtg
     9181 accaaaccct tctcttcgcg cgaactgctg gcacgcatca atgcagtgat ccgccgcacc
     9241 cggatgctgc cgccgaacct gcaggtgagc gaagcaggtc gccagctggc cttcggcgag
     9301 tggcgcctgg acaccactgc acgccatctg ctggatgcgc aggacaccgc gcatccgctc
     9361 agtggcgccg agttccgcct gttgcgcgtg ttccttgatc acgccaatcg ggtgctcagt
     9421 cgcgaccagc tgctcagcct cacccagggc cgcgatgccg aactgttcga tcgctcgatc
     9481 gacctgctgg tcagccgcgt gcgccagcgc ctgggtgacg acgcacgcga gccgacctac
     9541 atcaagaccg tgcgcagcga aggctatgtg ttcagcgtgc cggtgcagtt gctggggccg
     9601 gacgaatgaa cacggccgca cgtcgtccac gctggccgcg cacgctgtcg gcgcggctgc
     9661 tgctggtgct gctgggcgga ctggccctgg cccacgcact gtccttcggc ctgctgttct
     9721 tcgaacgtta ccagtccacc cgcagcatga tgctgcgcaa cctcgatgag gatgtggcgg
     9781 tcagtgtcgc gctgctggag cacctgcctg cggcgcaacg cgatgcctgg gtgcctcggc
     9841 tggagcggcg cacctaccgt tacctgctgc gcccggctgc ggccggaccg gggctgcaga
     9901 ccgatcgtgc acgccaggtc acggcgatca tcgacgacag cctgcagcac cgctatccgt
     9961 tgcagacgcg ccaggtagct cgcctgccgg agcggttcga ggtggaactg cgcctgcacg
    10021 acggtacccc cgtgaccatt gaagtcaccc cttcgggcct gccgctggcg cgttggctgc
    10081 ccgccgtgct gctgctgcag ctggcgctgc tgctggtctg cgcgtggctg gcggtgcgcc
    10141 tggccatgcg cccgctgcag cagctgtcgc atgcggtgga gcatctgcag ccgggcaagg
    10201 acgggcccgc actgcctgaa gatggtcctg cggaagtagg cggtgcggcg gccgcactca
    10261 atgcactgca ggcacgcatt cgtggccatg tcagtgagcg cctgcagatc ctggccgcga
    10321 tctcgcatga cctgcagact cccatcacgc gcatgaagct tcgggtggag accctgcctg
    10381 aagacagcac ccagcagcgg ctgctggccg acctcgacca cctgggtcaa ctggtgcgtg
    10441 agggcgtgtc ctatgcgcgc agcagccacg tcgccagtgg cgcgccggtg gcgatgcacc
    10501 tgggcgcatt cctggccagt gtggtcggcg attacgagga tatgggcaag ccggtcagtg
    10561 gtggtgcgcc ggctggactg gtcgtgcaga cctggccgca gccgctgcgc cgggtggtcg
    10621 gcaatctggt cgacaacgcg ttgcgttacg ccggtgccgc cgagatcgag gcgggtcgcg
    10681 atggggccgg aagggtgtgg atcagcattt ccgaccgtgg cccgggcatt cccgaggacc
    10741 agctgcaggc agtgctggcg ccgttccacc ggctggaaag ctcgcgcaat cgcggtaccg
    10801 gcgggactgg cctgggcctg gccatcgcgg tgcagctggc gcagtc
//
