LOCUS       NZ_CP045572            24890 bp    DNA     circular CON 07-NOV-2024
DEFINITION  Nonomuraea phyllanthi strain WYY166 chromosome, complete genome.
ACCESSION   NZ_CP045572
VERSION     NZ_CP045572.1
KEYWORDS    RefSeq.
SOURCE      Nonomuraea phyllanthi
  ORGANISM  Nonomuraea phyllanthi
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Streptosporangiaceae; Nonomuraea.
REFERENCE   1  (bases 1 to 11273186)
  AUTHORS   Ou,Y. and Wu,Y.
  TITLE     Nonomuraea nitratireducens sp. nov., a new actinobacterium isolated
            from Suaeda australis Moq. rhizosphere
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 11273186)
  AUTHORS   Ou,Y. and Wu,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-OCT-2019) School of Life Sciences and Biotechnology,
            Shanghai Jiao Tong University, Dongchuan, Shanghai 200240, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. Aug-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 160.0x
            Sequencing Technology             :: PacBio RSII; Illumina NextSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009497075.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 06:36:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,403
            CDSs (total)                      :: 10,325
            Genes (coding)                    :: 10,209
            CDSs (with protein)               :: 10,209
            Genes (RNA)                       :: 78
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 22 of 116
            Pseudo Genes (incomplete)         :: 104 of 116
            Pseudo Genes (internal stop)      :: 8 of 116
            Pseudo Genes (multiple problems)  :: 13 of 116
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:05:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7623364
            Orig. end                         :: 7648254
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP045572.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24890
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="20"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24890
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24890
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:14890]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14890
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(616..631)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.78"
                     /tool="antismash"
     gene            750..1718
                     /locus_tag="GBF35_RS35260"
                     /old_locus_tag="GBF35_35245"
     CDS             750..1718
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012892748.1"
                     /locus_tag="GBF35_RS35260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_35245"
                     /product="aldo/keto reductase"
                     /protein_id="WP_153264123.1"
                     /transl_table=11
                     /translation="MEYTRLGNTGLKVSRICLGMMSYGDPARQEWALARDEAEPIIRRA
                     ADAGVTFFDTADTYSRGASEVVTGEALRAIFPSRDDYVLATKVYFPMGRGANERGLSRK
                     HIHAAIDASLRRLGTDYVDLYQIHRWDDETPIEETMEALHDVVRAGKARYIGASTMWAW
                     QFSKAQHVAERNGWTKFVSMQNHYNLLYREEEREMLPLCADQGVGVIPWSPLARGVLAR
                     AGSAAATARTGSDSRIEFLYDPENDKAILDRVAQVARERGLPAAQVALAWLLRQPAVTA
                     PIVGATKDRHVDDAVAAVSVSLSESELAFLGDPYRPREVRF"
     gene            1759..3438
                     /gene="polX"
                     /locus_tag="GBF35_RS35265"
                     /old_locus_tag="GBF35_35250"
     CDS             1759..3438
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /gene="polX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546438.1"
                     /locus_tag="GBF35_RS35265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_35250"
                     /product="DNA polymerase/3'-5' exonuclease PolX"
                     /protein_id="WP_139632432.1"
                     /transl_table=11
                     /translation="MRANEEAAAALQEYAELFALCGGDAFRVRSYQKAAKAIAGFPEDI
                     SVVDVRSVPGVGEAIAKKMEEFLRRGSFRQLDDLRGRVPEGVRRLTRVPTLGPKTAIML
                     FEDFGIDSTEALGEAIASGRLDGVKGLGPKTLANLVKGIEQLEQSGRRVHIGAAMSLAE
                     QVMASLPAERIAYAGSLRRMKDTIGDIDILAVAPESIMADFRAQPYVAEVIAAGAKKTS
                     IRTTSGIQVDLRVVPAGSWGAAMQYFTGSKEHNVAIREMAVKKGWKLSEYGLFEGDRVI
                     AAASEEDIYDALGMRYVPPPMREDGGEVQAALRGELPVLVEPGDLKGDLHTHTDLTDGI
                     ASLADMVAAGHALGYAYYAVTDHAPDLAMQRMTLDKALEQRGQVAELQRKYPDMRILHG
                     TELNIAPDGSVDWPGEILAAFDVCVASVHSHFGMSRDEMTRRFIAACENPYVDIIGHPT
                     TRKIGKRPAVDADWDAVFRAAARTGTAMEIDSFPDRSDLPSDLVRLARHHGVKFSIDSD
                     SHAIPHLRNQRFGVGIAQRAWLTTDDVINTWPLDRLLAFLGR"
     gene            3489..3758
                     /locus_tag="GBF35_RS35270"
                     /old_locus_tag="GBF35_35255"
     CDS             3489..3758
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GBF35_RS35270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GBF35_35255"
                     /product="hypothetical protein"
                     /protein_id="WP_153264124.1"
                     /transl_table=11
                     /translation="MPPTAVPRSPAGDPVAPPAADRCLITPAGPLPATLDAWLSAASKD
                     PGTYAKSACQVSRWLNRHGGRSAVLSLVERLNSGERFASIVKPA"
     misc_feature    3702..3704
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(3970..4983)
                     /locus_tag="GBF35_RS35275"
                     /old_locus_tag="GBF35_35260"
     CDS             complement(3970..4983)
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (14-334). E-value: 6.7e-45.
                     Score: 145.5. Matches aSDomain:
                     nrpspksdomains_GBF35_RS35275_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019629239.1"
                     /locus_tag="GBF35_RS35275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_35260"
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="WP_153264125.1"
                     /sec_met_domain="ADH_N (E-value: 4e-10, bitscore: 38.8,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.6e-22, bitscore:
                     78.4, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSYHLDPQRGLAGLTVRDHDEPVPGRGQVVVKVRASSLGSRDLA
                     VLAGAYPLPIRPGVVPGCEGVGEVVAVGEGVGRVRAGDRVAATVFPRWLDGPFVWDNAA
                     QLGTMVDGMLTEYAVLGEDGVVPVPEHLSFEEAATLPLAAVTAWNALTTGSALRPGATV
                     LTLGSGAVSLFVLQLAKLSGAQVIMTTSSAAKAERLKALGADDVINYRDDPAWWQEVRA
                     LTHGAGVDRVVDATGPLEQSLKCVAAHGEVAFVGYSLSGAEGARPIDPATLFGAGAAVY
                     RVATGSRAHFVALNRAVEAHRLRPVLDRVFPFEHVADAFRYVESGGGFGKVVISHD"
     CDS_motif       complement(3982..4029)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GBF35_RS35275_0002"
                     /evalue="2.60E-03"
                     /label="PKSI-ER_m9"
                     /locus_tag="GBF35_RS35275"
                     /protein_end="334"
                     /protein_start="318"
                     /score="11.1"
                     /tool="antismash"
                     /translation="AFRYVESGGGFGKVVI"
     aSDomain        complement(3982..4941)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GBF35_RS35275_PKS_ER.1"
                     /evalue="6.70E-45"
                     /label="GBF35_RS35275_PKS_ER.1"
                     /locus_tag="GBF35_RS35275"
                     /protein_end="334"
                     /protein_start="14"
                     /score="145.5"
                     /tool="antismash"
                     /translation="LTVRDHDEPVPGRGQVVVKVRASSLGSRDLAVLAGAYPLPIRPGV
                     VPGCEGVGEVVAVGEGVGRVRAGDRVAATVFPRWLDGPFVWDNAAQLGTMVDGMLTEYA
                     VLGEDGVVPVPEHLSFEEAATLPLAAVTAWNALTTGSALRPGATVLTLGSGAVSLFVLQ
                     LAKLSGAQVIMTTSSAAKAERLKALGADDVINYRDDPAWWQEVRALTHGAGVDRVVDAT
                     GPLEQSLKCVAAHGEVAFVGYSLSGAEGARPIDPATLFGAGAAVYRVATGSRAHFVALN
                     RAVEAHRLRPVLDRVFPFEHVADAFRYVESGGGFGKVVI"
     CDS_motif       complement(4531..4575)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GBF35_RS35275_0001"
                     /evalue="5.20E-03"
                     /label="PKSI-ER_m4"
                     /locus_tag="GBF35_RS35275"
                     /protein_end="151"
                     /protein_start="136"
                     /score="10.4"
                     /tool="antismash"
                     /translation="AATLPLAAVTAWNAL"
     misc_feature    complement(4994..5012)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.29"
                     /tool="antismash"
     misc_feature    5005..5019
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.24"
                     /tool="antismash"
     misc_feature    5220..5234
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.62"
                     /tool="antismash"
     gene            5242..6288
                     /locus_tag="GBF35_RS35280"
                     /old_locus_tag="GBF35_35265"
     CDS             5242..6288
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546440.1"
                     /locus_tag="GBF35_RS35280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_35265"
                     /product="sulfite oxidase"
                     /protein_id="WP_153264126.1"
                     /transl_table=11
                     /translation="MEHATVTIVKPLPDHLFRVRDTNAEMRWEAMSGQGYHTPIDRFFV
                     RNHTSTPIIDAATWRLRVHGAGVRCPREFGYEQLRAMPSRTVDLAIECAGNGRRFYGTQ
                     QHDAAPGTQWGLGGIGVARWRGVPLRRLLEAAGPLPGAVDVLATGLDAPFEEYGHVRRP
                     LPIGKAMDDVLVAYEMNGEPLPPDHGFPVRLVVPGWVGIASIKWLGDIEVATAELRTPW
                     NTVFYPDVTVQPVKSAFELAWNARLPLTGPHVLRGRSWSGRGRIVRVEVSVDGGLSWRE
                     AEHHGRHLVSAWLPWHVSWAPSRTGAHVLMARATDETGATQPLFTPRHPFGYNFDAVVR
                     HPIEVVNG"
     misc_feature    complement(6322..6331)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.82"
                     /tool="antismash"
     misc_feature    complement(6395..6410)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.67"
                     /tool="antismash"
     gene            6430..>8292
                     /locus_tag="GBF35_RS54075"
                     /pseudo=""
     CDS             6430..>8292
                     /GO_function="GO:0004144 - diacylglycerol O-acyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0045017 - glycerolipid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Condensation_Starter (33-147). E-value:
                     3.3e-07. Score: 21.9. Matches aSDomain:
                     nrpspksdomains_GBF35_RS54075_Condensation_Starter.1"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018657.5"
                     /locus_tag="GBF35_RS54075"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="wax ester/triacylglycerol synthase
                     domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRRLTALDAQFLNVETATTAAHVAGLAIIDPAGGAVDRDALARLL
                     RERLHLSPALSLRLAEVPFGLDHPYWVADPDFDVDRHLFELTLPAPGDDRQLAEAVARI
                     HARRLDRARPLWEMHLINGLAGGRVAVYTKVHHAAIDGISGAETLAALLDLTPDGHLPS
                     QGLPASVTGRPCLPPDPPANAPAVSQVQAPAGPSTAAPADPRVEAPTGPRADSPAGSPT
                     EASDEPRASAPADPPTGASANAPVGAHAVEGRGLAVEGVGLSGTAAFCGGETAGPGAAV
                     RDGGGGARGEDASTSVRQEGVEPDRPRKDVPGQDGPARDGAGRDGLGMVAMLAEAAVRA
                     VTHPVRAVQSVVRAAEDLDAIPLAAQLPGARRIARAARRVAGDPQDRPELPGLAVPRTP
                     FNGPISARRHLSFGSVPLKDVRAVARANGLSVNDVVMGLCASALRSWLRERDALPEEPL
                     VVGVPVAVRTGGAGEVVGNQISAMVVPMPTNVSDPGERLRAAGAAMATAKRRFARAPAT
                     WLSELCSVLPAPLAGLATPALFRLAGTAFPPVNLVISNVPGPRFPLYLCGGRVLSYYPL
                     SVLTDMSGGLTITCFSYDGMLDFGVVACPERVDDVWGLLGHLRAA"
     aSDomain        6529..6870
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GBF35_RS54075_Condensation_Start
                     er.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="3.30E-07"
                     /label="GBF35_RS54075_Condensation_Starter.1"
                     /locus_tag="GBF35_RS54075"
                     /protein_end="147"
                     /protein_start="33"
                     /score="21.9"
                     /specificity="C activity: inactive"
                     /specificity="Active site motif: -------"
                     /tool="antismash"
                     /translation="GAVDRDALARLLRERLHLSPALSLRLAEVPFGLDHPYWVADPDFD
                     VDRHLFELTLPAPGDDRQLAEAVARIHARRLDRARPLWEMHLINGLAGGRVAVYTKVHH
                     AAIDGISGAE"
     gene            complement(8305..8862)
                     /locus_tag="GBF35_RS35295"
                     /old_locus_tag="GBF35_35280"
     CDS             complement(8305..8862)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012852531.1"
                     /locus_tag="GBF35_RS35295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_35280"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_139632429.1"
                     /transl_table=11
                     /translation="MVRAVVIGDARTRILDAAEELFAGGGYEATPTAVIARLAEVPKGL
                     IFHYFPRKIDVLVALVDERTLVEEGREVDAVPGDPARTLSRLARGLPLRASPAMRRILF
                     READTHGSVKERLGRLNGELIRRARFALELALPGARGDAARLEVAAATFAAVLLYQENL
                     CQLTGHQIDPDAVAELIAHSLV"
     gene            8990..9919
                     /locus_tag="GBF35_RS35300"
                     /old_locus_tag="GBF35_35285"
     CDS             8990..9919
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546444.1"
                     /locus_tag="GBF35_RS35300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_35285"
                     /product="aldo/keto reductase"
                     /protein_id="WP_153264127.1"
                     /transl_table=11
                     /translation="MRSIGTTDLSVFPISLGTNVFGWTADKETSFKVLDAYVEGGGNFI
                     DTADVYPYWATGESTSETIIGEWLHARRNRDSVVLATKVGMLEGLKGLAPATIRTAVED
                     SLRRLRTDYIDLYWAHVDDHDTPLVESLATFDALVREGKVRHVGASNYGADRLAEALKV
                     SGEEGLVRYVALQQQYNLVERGYEGGLRDVVAREGLSSTPYFGLARGFLTGKYAPGVTV
                     DSPRAGLAAEYLQKEYGRRTLDALAKVAAERSAAPATVALAWLAAQPTVAAPIASARDV
                     AQLQPLLAAAELELSEEELAVLDEASRP"
     gene            complement(10001..11011)
                     /locus_tag="GBF35_RS35305"
                     /old_locus_tag="GBF35_35290"
     CDS             complement(10001..11011)
                     /EC_number="2.5.1.-"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893340.1"
                     /locus_tag="GBF35_RS35305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_35290"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_226899758.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.9e-56, bitscore:
                     189.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRSHRLAGGAVARCRRLVEPALREAIAALHPWGARMSAYALGWS
                     DADGRPDTGLGGKGVRPAIAMLAAEAVGGTAESGLPGAVAVELVHAFSLAHDDIIDHDE
                     RRRHRDALWKAYGVGPALVTGDALLALAVSRLVGFPEAMRYLSAALIELVNGQTADMAF
                     ENRPWRGARAVTIDEYTAMVAGKTGSLLGAAAATGACLGGAPELGERMWEVGRDLGVAF
                     QIADDMLGIWGDPHVTGKPVYNDLRRDKKTIPVLAALAADHPAARTLSAMLSDGLSGED
                     AVRHAARLVEEAGGRAAAQALAERHVTAALAVLDECLPEATELRALCDSLANRIH"
     misc_feature    11038..11051
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.32"
                     /tool="antismash"
     misc_feature    complement(11084..11098)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.85"
                     /tool="antismash"
     gene            11134..12480
                     /locus_tag="GBF35_RS35310"
                     /old_locus_tag="GBF35_35295"
     CDS             11134..12480
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.5"
                     /locus_tag="GBF35_RS35310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_35295"
                     /product="cytochrome P450"
                     /protein_id="WP_194243964.1"
                     /sec_met_domain="p450 (E-value: 4.5e-57, bitscore: 193.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLGGVSSRRARTFPFLRSLARHARTPVHAFEEASRRAGGELVRL
                     NMGPFRPYLVTHPEHVQHVLKTNQPNYVRAGMFWDPLAPLLGQGILSEGEGWAASRKIL
                     QPVFTARYVNSLAGHMAQIITGLIDVTLVPGRRFDIGELISTLIHPTIVRLFLGATISD
                     EDIGRLAPAYDTGVTARSLRLLLPSVPERFPLPGDRAFKRAIRTIDEVVYPRIQYAKTR
                     REEDADLVSRLVRARPGEADADRLIRDDMVAIHGAATETSVTALTWVWPVLDAHPKIAA
                     RVYEEVDRVVGRGPVTVAHLQDLTYLKMFVDELVRLYPPGWILPRTAARADHIDGIEIP
                     AGATMVLSPYLTHRLPEFWDRALEFDPERFAPGNDRARHRYAYFPFAAGPHVCLGPHLF
                     MMEALLLIAGILCKYRPLLHTTGPITPRLASTLRPPKGLSMTLVPAGAA"
     gene            12477..13361
                     /locus_tag="GBF35_RS35315"
                     /old_locus_tag="GBF35_35300"
     CDS             12477..13361
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.4"
                     /locus_tag="GBF35_RS35315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_35300"
                     /product="terpene synthase family protein"
                     /protein_id="WP_228010395.1"
                     /sec_met_domain="T1TS (E-value: 9.9e-07, bitscore: 27.7,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGPGTTGPGMTGAGPAGLGAAAELGRTSALAVECARRLAAHAAE
                     HPDLFPAKPFDAGFFQSLGLVGAFGSPWASAGRLWAVNRAALWVFALDLQVDYVAKTRD
                     EVAALAEECLAVAGGAAPRGPLAADLAALRDDLGGDPRWRDQLERVLIAMLQEWDWRES
                     SATPALEEYLANADSCGSSFVNLSHWLYTGDTWTLDHLDVVREASDEVQRYLRLLNDLS
                     TYDREARWGDANALTLGAGRDEVTRRMARHARTAAGLIAPIHATSPRTAVYLERQIGFN
                     TGFYGVSDYWGEL"
     gene            13358..14890
                     /locus_tag="GBF35_RS35320"
                     /old_locus_tag="GBF35_35305"
     CDS             13358..14890
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013133479.1"
                     /locus_tag="GBF35_RS35320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_35305"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_228010396.1"
                     /sec_met_domain="T2TS (E-value: 2.6e-81, bitscore: 273.0,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVARESVDVAREANSLIATLMAMPWGQVSASVYETGRLVTLAPW
                     LTGHGERIDYLTRTQRPDGAWGAPGGYSVVPTLSATEALLTVGATEPAGRGLAALRRQL
                     PRMTDLPDMPAADLIVPALIALINAHPVGEPLPLPPGLDSSRVERVRRVLSSGAEPPQK
                     LLHALEVAGPASGGSSFVRPTVIGTVGASPAATAAWLGGAWLGTGALLDADSARSHLEA
                     VVARYGGPVPVGLPITVFERGWVLSWLARAGVPVEVPPEMVADLRAAIGPGGTPAGAGL
                     PPDADTTSVALYALALHGMARDPESLLAFDTGGHFCTWQGEDGFSISVNAHVLDAFGAY
                     AASGPDRADAYADVRERLARLLVERQRPDGSWDDRWHASPYYATLSCVLSLSEYGGPGL
                     APTVARARAWVLSSQRPDGSWGRWEGTPEETAYAMQTLLLPEAVNGGTVEERHRQAAAR
                     GHRFLQLSGEMSDYPPLWHDKDLYTPIAVVQAAILAARYVHARMVSTGQTWT"
     misc_feature    14780..14782
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(15019..15032)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.37"
                     /tool="antismash"
     gene            15072..17408
                     /locus_tag="GBF35_RS35325"
                     /old_locus_tag="GBF35_35310"
     CDS             15072..17408
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013133478.1"
                     /locus_tag="GBF35_RS35325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_35310"
                     /product="nitrate- and nitrite sensing domain-containing
                     protein"
                     /protein_id="WP_226899756.1"
                     /transl_table=11
                     /translation="MSLIALWGFAAWVTLREGVNLLGATTVDSGAVQPSERLLAELQRE
                     RRLSLVALGSGQRGPDKLMRDQRARTDEARAALTESATSASVQFAADDLLTRRIDEALR
                     SAQGIEALRKSVDSARADRDQTADSFNQIIDSLYLMFDSVASLDDKEIAKDARTILAIS
                     RASEYLSRADAIAAGALAKGRFTTSEHTEFVELAGFSRISLYQAAAQLPAEDAAAYNAW
                     AKSRAVAQLRGLEQQLAQQPDGMSPTVTGAEWRAATEAARTGLEKFITDGGDRLVDRSI
                     PGAVGVIVRLVLAGGLGLIAVVASIVLSITTTRQLLAQLRKLRDAAHDLSDERLPGVVE
                     RIGRGEEVDLAKEVPALDFGDDEIGQVGQAFNAVQRTAISVAAEQAELRRSIRDILLSL
                     ARRTQGLVHRQLTVLDVMERRETDPEELKELFRIDHLAIRMRRNAENLIVLSGSAPART
                     WRRSVPMVDVVRGALAEVEDYTRVTLMPMGDVVLVGRAVGDVIHLLAELIENAVSFSPP
                     YTNVQISGQLVANGYVVEIEDRGLGMKPEDLKVNNARIADPPEFRISGTARLGLYVVSQ
                     LARRHDIQVVLKASPYGGTTVVVLLPQDLVQLDPAPEPQDSGQRERLPRRTTAVATATR
                     PVAAENVRTLKPARQASPPVPAPAPSPGPAPAPASEPARGPAPGPAPKLSPVEAAPEPP
                     PTAEPEHQPVAEFTSNGLPLRVPQANLAPALRDDTPTQPDFEEDDDERSPEEIRRMMGS
                     LQSGTRLGRSEAAKMLEEQPPGGES"
     gene            17405..17824
                     /locus_tag="GBF35_RS35330"
                     /old_locus_tag="GBF35_35315"
     CDS             17405..17824
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019633192.1"
                     /locus_tag="GBF35_RS35330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_35315"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_139632424.1"
                     /transl_table=11
                     /translation="MTPTAGTDLNWLLDDLVGRVKEAEHAIVLSSDGLLMASSAGLQRT
                     DGEHLSAVASGLQSLAKGVSDHISGGAVRQTVVEWRSQFLIVTAAGERACLAVLCAQQA
                     DIGLVAYEMAMLVARVGQYLTSGARNAGAAAGSDR"
     gene            17821..18201
                     /locus_tag="GBF35_RS35335"
                     /old_locus_tag="GBF35_35320"
     CDS             17821..18201
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013133476.1"
                     /locus_tag="GBF35_RS35335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_35320"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_153264129.1"
                     /transl_table=11
                     /translation="MRGGTDGPTDEHWVDPEIIRPYVVTRGRTQPAHGRFDLISMALAV
                     GPTPGPDAGLDPEHLRILQLCREPKSVAEIAAYLDLPAGTIRVLLGDLFDRELVSAQEP
                     QSEVDMHDMKMYRAVLDGLRSL"
     gene            18182..18769
                     /locus_tag="GBF35_RS35340"
                     /old_locus_tag="GBF35_35325"
     CDS             18182..18769
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013133475.1"
                     /locus_tag="GBF35_RS35340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_35325"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_139632422.1"
                     /transl_table=11
                     /translation="MVFARSERPRLPTAIKILVAGGFGAGKTTMVGAVSETRPLRTEEV
                     LTDRGIGVDDLTSVEAKRTTTVAMDFGRITLGNDYVLYLFGTPGQERFWFVWDELAEGS
                     LGAVILADTRRLADCFPSVDYFERRGTPFVVAVNCFEGAPTFELEEVRLALQLSPSIPI
                     IMCDARKRESSREVLITLVKHSARLRAEPVGS"
     gene            complement(18798..19619)
                     /locus_tag="GBF35_RS35345"
                     /old_locus_tag="GBF35_35330"
     CDS             complement(18798..19619)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1066: alpha/beta hydrolase domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019474.5"
                     /locus_tag="GBF35_RS35345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_35330"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_139632421.1"
                     /transl_table=11
                     /translation="MITPEIPELRESARRRAAARPLGPALAHVEDLHGPGGLPLRRYRP
                     REQARPLMVFAHGGAFVMGDLDTHDRTCRRLAEACDVEVLAVDYRRAPEHPYPAAIDDV
                     AAVVRWSRPAAVAGDSAGGYLATMACLRLRDAGDPLPAVQILICPNTDLTLSQASVAEK
                     GSGYALDADFLTWAIAQWAPDPADRVAASPLLSPDLSGMPGGLVVTAEHDALRDEGDAY
                     ARRLAEAGARVTHRQERGLAHGFIQNMDLTSAAAAAAHDRLFHDIATLIHG"
     gene            complement(19832..20239)
                     /locus_tag="GBF35_RS35350"
                     /old_locus_tag="GBF35_35335"
     CDS             complement(19832..20239)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012891337.1"
                     /locus_tag="GBF35_RS35350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_35335"
                     /product="hypothetical protein"
                     /protein_id="WP_139632420.1"
                     /transl_table=11
                     /translation="MSITLTDQDELTMRTAAHGAVTLLAATDATGKPHKIATAGSIALT
                     SATGLVGHVLAGKPTGMDLTGRSVADIADHVLPALTATMSLLRKQAPAEAGTFRSTIIV
                     AIEAAARTHRGEPGPALTDMARRITAALDAA"
     gene            complement(20285..21514)
                     /locus_tag="GBF35_RS35355"
                     /old_locus_tag="GBF35_35340"
     CDS             complement(20285..21514)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017591630.1"
                     /locus_tag="GBF35_RS35355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_35340"
                     /product="serine hydrolase"
                     /protein_id="WP_153264130.1"
                     /transl_table=11
                     /translation="MENGDKGFSESGLRRLRDVLARYVDGGRIPGLVALVSRGDRTHVE
                     AMGTMRHDGGAAMRRDTIFRMASTSKPVSIAAAMVLLDECRLRLDDPVERWLPELADRR
                     VLRRIDGPLEETVPAHRPITVRDVLTSTFGLGMDMTSLGTPILNAIFERGLTPNLPVEV
                     PEPDEWLRRLGELPLMHQPGHRWQYHISSDLAGVLVARVTGRPFEEFLRERILDPLGMS
                     DTGFHVPAEHIDRLPTLYAPDPETGEFLVWDEAEDGRWSRPPAFQGGGGGLVSTADDYH
                     AYFRMLLNGGTHHGKRILSRPAVELMTTNRLTPDQQAARHAMAVDNVHISHGQGQHGGW
                     GLGMAVRTYRGDYAPIGQFGWDGGSGTATYADPAHHLTGILLTQVGASTPDSMHLIHDF
                     WTTLYQAIDD"
     gene            21650..24316
                     /locus_tag="GBF35_RS35360"
                     /old_locus_tag="GBF35_35345"
     CDS             21650..24316
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012895605.1"
                     /locus_tag="GBF35_RS35360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_35345"
                     /product="AAA family ATPase"
                     /protein_id="WP_153264131.1"
                     /transl_table=11
                     /translation="MLQGRAEEVRAVEALLAEARSGAGGVLVIRGEPGMGKSALLDHAA
                     RAAAGAGVLRGAGVETEVELPFAALHLLLRPALDRLDALPAPQAAALRGVFGLAPVAGT
                     DRFLVGLAALTLLSELAEERPLLVLVDDAQWLDRASAEALAFASRRLRSEGVTLLIAAR
                     DDRDAFPATGLPELRLGGLPRDDAERLLSDGLPAHLREQVLKEADGNPLALIELSRAAC
                     EGEWELGGTLPLTHRLQEAFTGQIHRLPEPARRLLAVAAAEDTGALGTVLAAAGALGIP
                     ADALEPAERAGLVTVTGGVVRFRHPLLRSAAYQGALSSQRRAIHRALAGSVSADRRAWH
                     LALAATGPDEHIAGALERSAEQAGARLGYAAMATAYERAAYLSTDQGRMARRLAAAAGA
                     AGEAGQSGRAADLSERAAQLTGDPVTLARLAEITSTAELDRGSPRRAASVLIDGAAPIA
                     GTDPRSAARMLAAASRNAWVGGDTALIAEASRLLDRLGLPPEDGLAALTRGLAHIHGGD
                     LESGYPLLDGFLRHASPADVEGQLTLTHPVFVAGRLDLARDLSTSLAARCRAEGRIRLL
                     PFVLDQLAYSRLMTGRHRDARDSAAEALQIALDTGQAHPTTGLRGMLAWLAAVEGDEER
                     CRAMAEEGVRFALARGSWPVDLLATWALAMLDLTQGRDQAALDRLQMRPRGSSHFSLRV
                     VVDEVEAAVRLGTPERVLEPLALFRRWAELSGEAWAGALVARCHGLIHDSEEHFTRALD
                     LHRLAEQPYEQARTHLAYGEWLRRRRRKAEARPHLRHARESFERLDARPWADRAAAELR
                     AAGEAPPTRRRADRGAALTAQELQVVRLAATGATNRDIAAHLLLSPRTVGQHLYKAFPK
                     LGVVSRTELARLELDRL"
ORIGIN
        1 gcgagcgcca gacgcagccc ggcttcaccc actggggttc cttcgccgag tacgtcgccg
       61 tcgaccacgc cgacgtcaat ctggtcgcgg tccccgagga catggccttc gccacggcgg
      121 ccggtctcgg ctgccgcttc gccaccgcgt tccgcgccgt ggcgcaggtc ggcgaggtgc
      181 ggccgggcga gtgggtggcg gtgcacggct gcggcggcgt gggcctgtcg gccgtgatga
      241 tcgcgacggc cgccggggcg cgcgtggtgg ccgtggacgt cagcgccgac gcgctcggcc
      301 tggcggagca ggcgggcgcc acccacttcg tcaacggctc ggccggtgac gcggccgccc
      361 aggtccagga gctgaccagg ggcggcgccc acgtgtcgct cgacgcgctg ggcagccctc
      421 agacgtgcgc cgcgtccgtc gagagcctgc gcaggaaggg ccggcacgta caggtggggc
      481 tgctgcccgg cggcccgacg ccggtgccga tggaccgggt gatcggccac gagctgcggc
      541 tgctgggcag ccacggcatg gccgcgcacg cgtacccgcc gatgctggag atgatcaggg
      601 ccgggatcct ccatcccgac cagctcgtca cccgcacgat cgggctggcc gacgccggca
      661 aggcgctggc gtcgatcggg tcggtgccgg gcgtgacgat gatcgcccca cgctccgccc
      721 tctgacctgg gagccctatc gtgggcgata tggaatacac gcgactcggc aacaccggtc
      781 tgaaggtctc gcggatctgc ctcggcatga tgagctacgg cgatccggcc aggcaggagt
      841 gggcgctggc gcgcgacgag gcggagccga tcatccgccg ggccgccgac gcgggcgtga
      901 cgttcttcga caccgccgac acctacagcc gcggcgcgag cgaggtcgtg acaggcgagg
      961 cgctgcgcgc gatcttcccc agccgtgacg actacgtgct ggccaccaag gtctacttcc
     1021 ccatgggcag gggcgccaac gagcggggcc tgtcgcgcaa gcacatccac gccgccatcg
     1081 acgcctcgct ccggcggctc ggcaccgatt atgtggacct ctaccagatc caccggtggg
     1141 acgacgagac gcccatcgag gagacgatgg aggcgctgca cgacgtggtc agggccggca
     1201 aggcccgcta catcggcgcg tccaccatgt gggcctggca gttctccaag gcgcagcacg
     1261 tggccgagcg caacggctgg acgaagttcg tctccatgca gaaccactac aacctcctct
     1321 accgggagga ggagcgcgag atgctgccgc tctgcgccga ccagggcgtg ggcgtgatcc
     1381 cgtggagccc gctggcgcgc ggcgtgctgg ccagggcggg ctcggccgcg gcgaccgccc
     1441 ggacgggctc cgactcgcgc atcgagttcc tgtacgaccc ggagaacgac aaggcgatcc
     1501 tcgaccgggt cgcgcaggtc gccagggagc ggggtctccc ggccgcccag gtcgccctgg
     1561 cctggctgct gcgccagccg gccgtgaccg cgcccatcgt gggggccacg aaggaccggc
     1621 acgtggacga cgccgtggcc gccgtgtcgg tgtcgctgag cgagtccgag ctggccttcc
     1681 tcggcgaccc gtaccggccg cgcgaggtgc gcttctagcc gtccaggatt gtcgggggcg
     1741 acccttaggg tgagggacat gcgggcgaat gaggaggcgg cggcggcgct gcaggaatac
     1801 gcggagctgt tcgcgctctg cggcggcgac gccttccggg tgcggagcta ccagaaggcg
     1861 gccaaggcca tcgccgggtt tcccgaggac atctcggtgg tcgacgtgcg ctcggtcccc
     1921 ggcgtgggcg aggcgatcgc caagaagatg gaggagttcc tgcggcgcgg gagcttccgg
     1981 cagctcgacg acctgcgcgg gcgggtgccc gagggggtgc gcaggctgac gcgggtgccg
     2041 acgctggggc ccaagacggc catcatgctg ttcgaggact tcggcatcga ctccaccgag
     2101 gcgctgggcg aggcgatcgc ctccggccgg ctcgacggcg tcaaggggct cggcccgaag
     2161 acgctggcca acctggtcaa gggcatcgag cagctggagc agtcgggccg gcgcgtccac
     2221 atcggggcgg ccatgtcgct ggccgagcag gtgatggcct cgctgccggc cgagcgcatc
     2281 gcgtacgcgg ggtcgctgcg gcggatgaag gacacgatcg gcgacatcga catcctcgcg
     2341 gtcgcgcccg agtcgatcat ggccgacttc cgcgcccagc cctacgtcgc cgaggtgatc
     2401 gcggcgggcg ccaagaagac ctcgatccgc accacgtccg gcatccaggt cgacctgcgc
     2461 gtggtgcccg ccgggtcgtg gggcgcggcg atgcagtact tcacgggttc caaggagcac
     2521 aacgtcgcca tcagggagat ggcggtgaag aagggctgga agctgtcgga gtacggcctg
     2581 ttcgagggcg atcgggtgat cgccgccgcc tccgaggagg acatctacga cgccctcggc
     2641 atgcgctacg tgccgccgcc gatgcgcgag gacggcggcg aggtgcaggc ggcgctgcgc
     2701 ggcgagctgc ccgtcctggt ggagccaggt gacctgaagg gcgacctgca cacccacacc
     2761 gacctgaccg acggcatcgc ctcgctggcc gacatggtgg cggccgggca cgccctcggc
     2821 tacgcgtact acgcggtgac cgaccacgcg cccgacctgg cgatgcagcg gatgacgctg
     2881 gacaaggcgc tggagcagcg ggggcaggtg gccgagctgc aacggaaata tcccgacatg
     2941 cggatcctgc acggcacgga gctcaacatc gcgcccgacg ggtcggtcga ctggcccggg
     3001 gagatcctgg ccgcgttcga cgtgtgcgtg gcctcggtgc actcccattt cgggatgtca
     3061 cgcgacgaga tgacccgccg gttcatcgcc gcctgcgaaa acccgtacgt ggacatcatc
     3121 gggcatccca ccacccgcaa gatcggcaag cggccggccg tggacgccga ctgggacgcc
     3181 gtcttccgcg cggccgcccg cacggggacc gccatggaga tcgactcctt ccccgaccgg
     3241 tccgacctgc cgtccgacct ggtgcggctg gccaggcacc acggggtgaa gttctcgatc
     3301 gacagcgact cgcacgccat cccccacctg cgcaaccagc ggttcggggt gggcatcgcg
     3361 cagcgggcct ggctgacgac ggacgacgtc atcaacacct ggccgctgga ccggctcctg
     3421 gcgttcctgg gccgctgatc cgccggcccg cccgagggcg gttccgtcac gccggcgcgc
     3481 caccttccgt gcccccgaca gccgtacccc gttctccggc cggcgacccg gtcgctcccc
     3541 ccgctgcgga ccgctgcctg atcacgccgg caggcccgct cccggccacg ctcgacgcgt
     3601 ggctgagcgc ggcgagcaag gacccgggca cgtacgccaa gtccgcctgc caggtgagcc
     3661 gctggctcaa ccggcacgga ggccgcagcg cggtcctctc cttagtcgaa cgcctcaact
     3721 ccggcgagcg gttcgcctcg atcgtgaagc ccgcctgacc tcggccccat cgaggccacg
     3781 cacacccacg gctcaggagc cggcgctggt cacagcccat gcgccctgag tgtccaccca
     3841 cggtgtccac cgacgggccg tccggccgtc ggccagccgt ccggccgtcg cgaaaccggc
     3901 accaccgggc cacgcgtggg gccggatccc gactgatcag gcggaaaccc tcgggccccg
     3961 ctcggccggt cagtcgtggc tgatgaccac cttgccgaaa ccaccgccag actccacgta
     4021 gcggaaggcg tcagcaacat gctcgaacgg gaacacgcgg tccaggaccg gacgcagccg
     4081 gtgggcctcg acggcgcggt tcagcgcgac gaagtgggcc cggctgcccg tggcgacgcg
     4141 atacaccgcc gcgcccgccc cgaacagggt cgccgggtcg atgggccggg ctccctcggc
     4201 gccggacagc gagtagccga cgaaggccac ctcgccgtgg gccgcgacgc acttgagcga
     4261 ctgctccagc ggccccgtcg cgtcgacgac acggtccacg ccggcaccgt gggtgagagc
     4321 acgcacctcc tgccaccagg ccgggtcatc ccggtagttg atcacgtcgt ccgccccgag
     4381 cgccttcagc cgttcggcct tggcggcgct ggacgtggtc atgatcacct gggcgccgga
     4441 cagcttggcg agctgcagca cgaagagcga cacggctccc gaccccaggg tcagcacggt
     4501 ggcccctggg cgcagcgcgc tgcccgtggt cagggcgttc caggcggtca cggccgccag
     4561 cggcagcgtc gcggcctcct cgaacgacag gtgctccggg acgggcacga cgccgtcctc
     4621 gcccagcacg gcgtactccg tcaacatgcc gtcgaccatc gtcccgagct gggcggcgtt
     4681 gtcccacacg aacgggccgt ccagccagcg ggggaagacg gtggccgcca cccggtcgcc
     4741 ggcccgcacc cggccgaccc cttccccgac ggccacgacc tcccccaccc cctcgcaccc
     4801 gggcaccacg ccgggtctga tcggcagcgg gtaggcgccg gccagcaccg ccagatcacg
     4861 tgacccgagc gagctcgcac ggaccttgac cacgacctgt ccgcgtcccg gcacgggctc
     4921 gtcatgatcc ctgaccgtca gcccggccag gccacgctgc ggatcaaggt gatagctctt
     4981 catctcgtcg ccttctcagt cgccttctca atcgtcgagc tcgatcgcgg gctgccccca
     5041 gcgccatggg gatcatgcgt gtcagccggg gcttccggca attccttcga gggagtcgcc
     5101 ggcggcgggt aagcgcgagg gcggctgggc ggaacgttcc cgtacggatc gggcagggat
     5161 ctgcaaggac gggcgccaca ggacaggccg aggagattaa atggtttcca ggtaggaaat
     5221 actcaatagg aggtgacgac catggagcac gcgacggtca cgatcgtgaa accgctgccc
     5281 gaccacctgt tcagggtgcg cgacacgaac gcggagatgc ggtgggaggc catgtcgggg
     5341 cagggatacc acaccccgat cgaccggttc ttcgtgcgga accacacctc caccccgatc
     5401 atcgacgccg ccacgtggcg gttgcgggtg cacggggcgg gggttcgatg tccgcgcgag
     5461 ttcggctatg aacagctgcg ggcgatgcca tcgcggacgg tcgacctggc gatcgagtgc
     5521 gcggggaacg ggcggcggtt ctacggcacg cagcagcacg acgccgcccc cgggacgcag
     5581 tgggggctgg gcgggatcgg ggtcgcgcgg tggcggggcg tgccgttgcg gcgcctgctg
     5641 gaggcggccg ggccgctccc cggggcggtg gacgtgctgg cgaccgggct cgacgcgccg
     5701 ttcgaggagt acgggcacgt acgcaggccg ctgccgatcg gcaaggccat ggacgacgtc
     5761 ctggtggcgt acgaaatgaa cggcgagccg ctgcctccgg accacggatt cccggtacgg
     5821 ctggtggtgc cgggatgggt gggaatagcc tccatcaaat ggctgggcga tatcgaggtc
     5881 gccaccgcgg agctccgtac accgtggaac acggtctttt acccggacgt caccgtccag
     5941 ccggtgaaga gcgcgttcga gctcgcctgg aacgcgcgcc tgccgctcac cggaccacac
     6001 gtcctgcgcg ggcggtcctg gtcggggcgg ggcaggatcg tccgggtgga ggtcagcgtg
     6061 gacggcgggc tgagctggcg cgaggccgag caccacgggc ggcacctggt cagcgcgtgg
     6121 ctgccctggc acgtgtcatg ggcaccgagc cgcacggggg ctcatgtgct catggcgcgc
     6181 gccaccgacg agacgggcgc cacgcagccg ctcttcaccc cgcggcaccc gttcggatac
     6241 aacttcgacg ccgtcgtccg gcatcccatt gaggtggtca atggataggt aattgtcacc
     6301 gatccgggct gagctgggca ttcataaaac ggcggtacgg cgcaccggaa ttcatctgaa
     6361 agactctcgc ggaaaccatc tcgaaatccc ttcgtgtgac gctgcgcaca gcacgggaaa
     6421 ggagagcaga tgcgccggct gaccgcactc gacgcccagt tcctcaatgt cgagacggcg
     6481 accaccgccg cgcacgtggc ggggctggcg atcatcgacc cggccggcgg agcggtcgat
     6541 cgggatgctc tcgcgcgcct gctgcgggag cgcctccacc tgtcgcccgc gctcagcctc
     6601 cggctggccg aggtgccgtt cgggctggac cacccgtact gggtggccga ccccgacttc
     6661 gacgtcgacc gccacctctt cgagctgacg ctgcccgcgc cgggggacga ccggcagctg
     6721 gccgaggcgg tggcgcggat ccacgcgcgc cggctggacc gggcgcgtcc gctgtgggag
     6781 atgcacctga tcaacgggct ggccggtggg agggtcgccg tgtacacgaa ggtgcaccat
     6841 gccgccatcg acggcatctc gggcgctgag acgctggccg ccctgctcga cctcacccct
     6901 gacggccacc tgccgagcca gggcctcccg gcctcggtca ccgggcgccc ctgccttcct
     6961 cccgacccgc cggcgaacgc ccctgccgtc tctcaggtgc aggctcccgc cggcccttcc
     7021 acggccgccc ctgccgaccc tcgggtggag gcacccaccg gccctcgggc ggactctccc
     7081 gccggctccc ccacggaagc gtctgacgag cctcgggcga gcgcccctgc cgaccctccc
     7141 accggcgcct ccgccaacgc tccggtgggt gcccacgccg tggagggccg ggggctcgcg
     7201 gtggagggtg tgggcctttc cgggacggcg gccttctgtg gcggtgagac ggctggtccc
     7261 ggagcggcgg tgcgcgacgg tggtggcggg gcgagagggg aggatgcgtc cacgtcggtg
     7321 aggcaggagg gcgtcgagcc tgaccggccc cggaaggacg tacccgggca ggatgggcct
     7381 gcgcgggacg gcgccgggcg tgatgggctc gggatggtgg cgatgctggc ggaggcggcg
     7441 gtgcgggcgg tgacgcatcc ggtgcgggcc gtccagtccg tcgtcagggc ggccgaggat
     7501 ctcgacgcca tcccgctggc cgcgcagctc ccgggggccc ggcgcatcgc cagggccgcg
     7561 cggcgggtcg ccggtgaccc gcaggaccgc cccgagctgc ccggcctggc ggtccctcgc
     7621 accccgttca acggccccat cagcgcccgc cgccatctct ccttcggctc ggtcccgctc
     7681 aaggacgtca gggccgtcgc ccgggccaac ggcctgagcg tcaacgacgt cgtcatgggc
     7741 ctgtgcgcct cggcgctgcg gtcgtggttg cgggagcggg acgcgctgcc ggaggagccg
     7801 ctggtcgtcg gcgtgcccgt ggcggtgcgt acgggcggcg ccggcgaggt ggtcggcaac
     7861 cagatctccg ccatggtcgt ccccatgccg acgaacgtct ccgaccccgg ggagcgcctg
     7921 cgggcggcgg gcgccgccat ggccacggcc aagcggcgtt tcgcgcgggc cccggcgacg
     7981 tggctgagcg agctgtgctc ggtgctgccc gcgccgctgg cggggctggc cacgccggcg
     8041 ctcttccggc tggcgggtac ggcgttcccg ccggtcaacc tcgtcatcag caacgtgccc
     8101 ggcccgcggt tcccgctgta tctgtgcggc ggcagggttc tgtcgtacta tccgctgtcg
     8161 gtgctgaccg acatgagcgg cggcctgacc atcacctgct tctcctacga cggcatgctc
     8221 gacttcggcg tcgtggcctg tcccgagcgg gtggacgacg tgtgggggct gctcggccac
     8281 ctgcgtgcgg cgctcggcga gctgctagac gagggagtgg gcgatgagtt ccgcgacggc
     8341 gtcggggtcg atctggtgcc cggtcagctg gcagaggttc tcctggtaga gcaggacggc
     8401 ggcgaacgtg gccgccgcca cctccagcct ggcggcgtcg ccgcgggctc cgggcagggc
     8461 cagctccagc gcgaacctgg cccgcctgat gagctcgccg ttgagccggc cgagccgctc
     8521 cttgacggag ccgtgcgtgt cggcctccct gaacaggatg cgccgcatcg ccggtgaggc
     8581 ccgcaggggc aggccgcgcg cgagcctgga cagggtccgc gcggggtcgc cgggcacggc
     8641 gtcgacctcg cgtccctcct cgaccagggt gcgctcgtcg acgagggcga cgagtacgtc
     8701 gatcttgcgc gggaagtagt ggaagatcag ccctttgggc acttcggcga gccgggcgat
     8761 gaccgcggtg ggggtggcct cgtagccgcc gcccgcgaac agctcctcgg ccgcgtccag
     8821 gatgcgcgtg cgcgcgtcac cgatcaccac agctcgcacc atagcgccac ctgcgagttc
     8881 gccgccatcc cgagaacggc agacccccat ccccgacggg gccggagggg cggctcgtgg
     8941 tgcgggggtg gccccgggcc ggccgcgagg gggtgccgat aatggcggga tgagatcaat
     9001 aggcacaacg gacctgtccg ttttcccgat atcgctcggt acgaatgtct tcggctggac
     9061 ggccgacaag gagacctcgt tcaaggtcct ggacgcgtac gtcgagggcg gcggcaactt
     9121 catcgacacg gccgacgtct acccgtactg ggcgaccggc gagtcgacct cggagacgat
     9181 catcggcgag tggctgcacg cgcgccgcaa ccgcgactcg gtcgtcctcg ccaccaaggt
     9241 cggcatgctg gaggggctga agggcctggc cccggccacc atcaggacgg cggtcgagga
     9301 ctccctgcgc cggctccgta ccgactacat cgacctgtac tgggcgcacg tggacgacca
     9361 cgacacgccg ctggtggagt ctctggcgac gttcgacgcg ctggtccgcg agggcaaggt
     9421 ccggcacgtc ggggcgtcca actacggggc cgaccggctg gcggaggcgc tcaaggtctc
     9481 cggcgaggag gggctggtca ggtacgtcgc cctgcagcag cagtacaacc tggtcgagcg
     9541 ggggtacgag ggcgggctgc gggacgtggt ggcccgggag gggctgtcca gcacgccgta
     9601 cttcgggctg gcgcgcggct tcctgaccgg caagtacgcg cccggcgtga cggtcgacag
     9661 cccgcgggcc gggctggcgg cggagtacct ccagaaggag tacgggcgcc ggaccctgga
     9721 cgcgctggcg aaggtcgcgg ccgagcgctc ggcggctcct gccacggtgg cgctcgcctg
     9781 gctggccgcc cagcccacgg tcgcggcccc gatcgccagc gccagggacg tggcccagct
     9841 ccagccgctc ctggccgccg cggagctgga gttgagcgag gaggagctgg ccgtcctgga
     9901 cgaggcctcc cgcccctgac gggggccacg cccgccgcgg ccggccgccc ggcgcccgcc
     9961 caggggtgcc gggcacccct ccacggggaa ccgccggagg tcagtggatg cggttcgcga
    10021 gcgagtcgca caacgcgcgc agttccgtgg cctccggcag gcattcgtcc aggaccgcca
    10081 gcgccgcggt gacatgccgc tcggccaggg cctgggcggc ggcgcgcccc ccggcctcct
    10141 ccacgaggcg ggcggcgtgg cggaccgcgt cctcccccga gaggccgtcc gagagcatgg
    10201 cggacagcgt gcgcgcggcc gggtggtccg cggcgagcgc cgccaggacg ggaatcgtct
    10261 tcttgtcgcg ccgcagatcg ttgtagacgg gcttgccggt gacatgtgga tcgccccaga
    10321 tgcccagcat gtcgtcggcg atctggaacg ccacccccag gtcgcgcccc acctcccaca
    10381 tgcgctcgcc gagctccggc gcgccgccca ggcacgcccc ggtcgccgcg gcggccccca
    10441 gcaggctgcc ggtcttgccc gccaccatcg ccgtgtactc gtcgatcgtc accgcccggg
    10501 ccccgcgcca ggggcggttc tcgaaggcca tgtcggcggt ctgcccgttg acgagctcga
    10561 tcagggccgc ggacaggtac cgcatcgcct cggggaagcc cacgagccgg ctgacggcca
    10621 gggcgaggag cgcgtcgccg gtcacgagcg ccgggcccac gccgtacgcc ttccacaggg
    10681 cgtcgcggtg ccgccgccgc tcgtcgtggt cgatgatgtc gtcgtgcgcc agcgagaagg
    10741 cgtgcaccag ctccaccgcc accgcgccgg gaagccccga ctcggcggtg ccgcccaccg
    10801 cctcggcggc gagcatggcg atggcggggc gcacgccctt gccgccgagc ccggtgtcgg
    10861 gccggccgtc cgcgtcggac cagcccaggg cgtacgcgga catcctggca ccccaggggt
    10921 gcagggccgc gatcgcctcc ctcagagccg gttcgaccag gcgccggcag cgggccacgg
    10981 cgccgccggc caagcggtga ctgcgattca atgggtgctc ctacccggat acgatcttga
    11041 atctacatgc agaagcatgt gatactccac cccatagatt gacgcttgtc aggaaatgtc
    11101 cgtcgtttga gacggacatc atggaggtcc gcggtgtcgt tgggcggcgt atcgtcgcgt
    11161 cgggcaagaa cctttccgtt cctccgatca ctggccaggc acgcgcgaac acccgtacac
    11221 gccttcgagg aggcgagcag gcgggcgggc ggcgagctcg tccggctgaa catgggccct
    11281 ttccgcccct acctcgtcac ccaccccgag cacgtccagc acgtcctgaa gaccaaccag
    11341 ccgaactacg tccgggccgg catgttctgg gacccgctgg ccccgctgct cggccagggc
    11401 atcctgtcgg agggcgaggg ctgggcggcc agccggaaga tccttcagcc ggtgttcacc
    11461 gccaggtacg tcaactcgct cgccgggcac atggcgcaga tcatcaccgg cctgatcgac
    11521 gtcaccctgg tgccgggccg ccgcttcgac atcggcgaac tcatctccac cctgattcat
    11581 ccgaccatcg tgcggttgtt cctcggggcg acgatctccg acgaggacat cggccgcctg
    11641 gcccccgcct acgacacggg cgtgacggcc aggtcgctcc ggttgctgct gccctccgtg
    11701 ccggaacgtt tcccgctgcc cggcgaccgg gcgttcaagc gggcgatcag gaccatcgac
    11761 gaggtcgtct acccccgcat ccagtacgcc aagacgcggc gtgaagagga tgccgacctg
    11821 gtctccaggc tggtccgcgc gcgcccgggc gaggcggacg cggacaggct gatcagggac
    11881 gacatggtgg ccatccacgg cgccgccacg gagacctccg tcaccgcgct cacctgggtg
    11941 tggccggtgc tggacgcgca cccgaagatc gccgcccggg tgtacgagga ggtggaccgc
    12001 gtggtcgggc gcggcccggt cacggtcgcg cacctgcagg acctgacgta cctgaagatg
    12061 ttcgtggacg agctggtccg cctctacccg cccggctgga tcctgcccag gacggcggca
    12121 cgggccgatc acatcgacgg gatcgagatc cccgccgggg ccacgatggt gctcagcccg
    12181 tacctgacgc accggctgcc ggagttctgg gaccgggcgc tggagttcga tccggagcgg
    12241 ttcgcgccgg gcaacgaccg ggcgcggcac cggtacgcgt acttcccgtt cgctgcggga
    12301 ccgcacgtct gcctgggacc gcacctgttc atgatggagg ccctgctcct gatcgccggg
    12361 atcctgtgca agtaccgccc gctgctgcac acgaccggcc cgatcactcc gcggctggcc
    12421 tcgacgctgc ggccccccaa ggggctgtcg atgacgctcg ttccagcggg tgccgcatga
    12481 ccggccccgg cacaaccggc cccggcatga ccggcgccgg ccctgccgga ctcggcgcgg
    12541 cggccgagct cggtaggacc agcgcgctgg cggtcgagtg cgcccgccgg ctcgccgcgc
    12601 acgccgccga gcacccggac ctcttccccg ccaagccgtt cgacgccggt ttcttccagt
    12661 ccttggggct ggtcggcgcg ttcggctccc cctgggcctc cgcgggacgg ctctgggcgg
    12721 tcaaccgcgc cgcgctgtgg gtgttcgcac tggacctgca ggtcgactac gtcgcgaaga
    12781 cccgcgacga ggtggccgcg ctggccgagg agtgcctggc ggtggcgggt ggggcggcgc
    12841 cgcgcggccc gctcgccgcc gacctcgccg cgctccgcga cgacctggga ggcgacccgc
    12901 gctggcggga ccagctcgaa cgcgtgctga tcgccatgct ccaggagtgg gactggcgcg
    12961 agtcgagcgc cacgcccgcc ctggaggagt acctggccaa cgcggacagc tgtggctcct
    13021 cgttcgtcaa cctctcgcac tggctctaca ccggcgacac gtggacgctg gaccacctgg
    13081 acgtcgtacg cgaggcgagc gacgaggtgc agcgctacct gcggctgctg aacgacctga
    13141 gcacgtacga cagggaagcc cgctggggcg acgccaacgc gctgacgctg ggcgcggggc
    13201 gtgacgaggt cacgcggcgc atggcgcggc acgcgcgtac ggcggccggg ctgatcgcgc
    13261 cgatccacgc gaccagcccg cggaccgccg tctacctgga gcgccagatc ggcttcaaca
    13321 ccggtttcta cggcgtttcc gactattggg gagaactgtg aacgtcgccc gcgagtccgt
    13381 ggacgtcgcc cgcgaggcga actcgctgat cgccacgctg atggccatgc catggggtca
    13441 ggtgtccgcg tccgtctacg agacggggcg gctggtgacg ctggccccgt ggctgaccgg
    13501 gcacggcgag cgcatcgact atctcacgcg gacccagcgt ccggacggag cctggggcgc
    13561 gccgggcggc tacagcgtgg tgccgacctt gagcgccacc gaggccctgc tcaccgtcgg
    13621 ggccacggag cccgccggca gggggctggc ggcgctgcgc cggcagctcc cccggatgac
    13681 cgatctgccc gacatgccgg ccgccgatct gatcgtcccg gcgctgatcg ccctcatcaa
    13741 cgcgcacccc gtgggcgagc cgctccccct gccgcccggc ctggactcct cccgcgtcga
    13801 acgggtccgt cgcgtgctgt catccggggc cgagccgccg cagaagctgc tccacgctct
    13861 cgaggtggcc ggtcccgcgt cgggaggatc gagcttcgtc cgcccgacgg tcatcggcac
    13921 ggtcggagcc tctcccgccg cgaccgccgc ctggctcggc ggcgcctggc tcggcacggg
    13981 cgccctgctc gacgccgact cggcgagaag ccatctggag gcggtagtcg ccaggtacgg
    14041 cgggccggtc cccgtcgggc tgcccatcac cgtgttcgag cgtggctggg tgctgagctg
    14101 gctggcccgg gcgggcgtgc ccgtcgaggt tccgccggag atggtggccg acctcagggc
    14161 ggcgatcggc cccggcggca cgccggcggg ggcggggctg cccccggacg cggacacgac
    14221 ctccgtcgcg ctgtacgcgc tggcgctgca cgggatggcg cgcgatccgg agagcctgct
    14281 ggcgttcgac acaggggggc acttctgcac gtggcagggc gaggacggct tctccatcag
    14341 cgtgaacgcc catgtcctcg acgcgttcgg cgcgtacgcc gcctccgggc cggaccgcgc
    14401 ggacgcgtac gcggacgtcc gggaaaggct ggcgcgcctg ctggtggagc ggcagcggcc
    14461 ggacggaagc tgggatgatc gctggcacgc gtccccgtat tacgccacac tgagttgcgt
    14521 gttgtcgctc agcgagtacg gcgggccagg gctcgccccc acggtggcca gggcccgggc
    14581 ctgggtgctg tcgtcgcagc gccccgacgg gtcgtggggc cgctgggagg gcacgcccga
    14641 ggagaccgcg tacgcgatgc agacgttgtt gctgcccgag gccgtgaacg gcggtaccgt
    14701 cgaagagcgg caccgccagg ccgccgcccg cggccaccga tttctccaac tatcgggcga
    14761 aatgtcggat tacccaccat tatggcatga caaggacctt tacaccccga tagcagtcgt
    14821 ccaggcagcc atcctggcgg ctcgctatgt ccatgcaagg atggtttcga caggtcaaac
    14881 ctggacgtaa tctcccgtac tggattttct cgccttgagc tggatttgag gcattgctaa
    14941 ggtatcccgg tgccaaagcc tcgaaatgca cccgagcgcc ttgacatctg gcttaacgta
    15001 acccccgacc tggacggcta aatatgcgtt tgcgcaacgt cagcgtgcgg acaaaggtga
    15061 cagccctgct ggtgtcactg atcgcactgt gggggttcgc cgcctgggtc accttgcgcg
    15121 agggcgtgaa cctcctcggc gccacgaccg tcgacagcgg tgcggtgcag cccagcgagc
    15181 gcctgctcgc cgagttgcag cgcgagcgtc gcctctccct ggtggcgctg ggctccggcc
    15241 agcgcgggcc cgacaagctg atgcgcgacc aacgggccag gaccgacgag gcgcgcgcgg
    15301 cactcacgga gtcggcgacc agcgccagcg tccagttcgc ggccgacgat ctgctcacgc
    15361 gccgcatcga cgaggcgctg aggagcgcgc aggggatcga ggcgctcagg aagtcggtcg
    15421 actccgcacg cgccgaccgc gaccagacgg ccgattcctt caaccagatc atcgactcgc
    15481 tctacctcat gttcgactcg gtcgcctcgc tggacgacaa ggagatcgcc aaggacgcgc
    15541 gcaccatact cgcgatcagc cgggccagcg aatacctgtc ccgcgccgac gcgatcgccg
    15601 ccggtgcgct ggccaagggc cggttcacca cgtcggagca caccgagttc gtggagctgg
    15661 ccgggttctc ccgcatctcc ctctaccagg ccgcggcgca gctcccggcg gaggacgcgg
    15721 ccgcgtacaa cgcctgggcg aagagccgcg ccgtcgccca gttgcgcggc ctggaacaac
    15781 agctcgccca gcagcccgac ggcatgtccc ccacggtgac gggcgccgag tggcgcgcgg
    15841 ccaccgaggc ggcccgcacc ggtctggaga agttcatcac cgacggcggc gaccgcctcg
    15901 tcgaccggtc catccccggc gccgtcggcg tcatcgtccg cctcgtcctg gcgggtggcc
    15961 tcggcctgat cgcggtcgtg gcctcgatcg tgctgtcgat caccaccacc cggcagctgc
    16021 tcgcccagct gcgcaagctg cgcgacgccg cacacgacct gtccgacgaa cggcttcccg
    16081 gcgtcgtcga gcgcatcggc cgcggcgagg aggtcgacct cgccaaggag gtgccggcgc
    16141 tggacttcgg tgacgacgag atcggccagg tgggccaggc gttcaacgcc gtgcagcgca
    16201 ccgccatcag cgtcgccgcc gagcaggccg agctgcgccg cagcatccgc gacatcctgc
    16261 tcagcctggc ccgcaggacg cagggcctgg tccaccggca gctcaccgtc ctcgacgtga
    16321 tggagcgccg cgagaccgac ccggaggagc tgaaggagct cttccggatc gaccacctcg
    16381 ccatccggat gcggcgcaac gccgagaacc tcatcgtgct gtccggctcc gcccccgccc
    16441 gtacgtggcg ccgctcggtc cccatggtcg acgtcgtccg cggcgccctg gccgaggtcg
    16501 aggactacac ccgcgtcacg ctcatgccga tgggcgacgt cgtgctggtc ggccgtgccg
    16561 tcggtgacgt catccacctg ctcgccgagc tgatcgagaa cgccgtgtcg ttctcgccgc
    16621 cctacacgaa cgtgcagatc agcgggcagc tggtggccaa cggctacgtc gtcgagatcg
    16681 aggaccgcgg cctcggcatg aagcccgagg acctcaaggt caacaacgcg cgcatcgccg
    16741 acccgcccga gttccgcatc tccggcaccg cccggctggg cctctacgtg gtcagccagc
    16801 tcgccaggcg ccacgacatc caggtggtgc tcaaggcctc gccgtacgga gggaccacgg
    16861 tcgtggtgct gctgccgcag gacctcgtgc aactcgaccc cgcgcccgag ccgcaggaca
    16921 gcgggcagcg cgagcggctg ccgcgccgga cgacggccgt ggccaccgcg acccggccgg
    16981 tcgccgcgga gaacgtccgc acgctcaagc cggcgcgtca ggcttccccg cccgttcctg
    17041 cccccgcacc ctccccgggc cccgcaccgg cccccgcttc tgagcccgcc cgcgggcccg
    17101 ctcctgggcc cgcccccaag ctcagccccg tggaagcggc tcccgagccg ccgcccaccg
    17161 ccgagccgga gcaccagccc gtggccgagt tcacgtccaa cgggctgccc ctccgggtgc
    17221 ctcaggccaa cctggcgcca gcgctgcggg acgacacgcc cacgcagccc gacttcgagg
    17281 aggacgatga cgagcgctcg ccggaggaga tccgcagaat gatgggatct ctgcagtcag
    17341 gcacccgtct tggccgcagc gaagccgcca agatgctgga agagcagccg cccggaggtg
    17401 agtcatgacc cccactgcgg gcaccgacct caactggctg ctcgacgatc tcgtcggccg
    17461 cgtcaaggag gccgagcacg ccatcgtgct gtcgtccgac ggcctgctga tggcctcctc
    17521 cgccgggctg cagcggaccg acggcgagca cctgtccgcc gtcgcctccg ggctgcagag
    17581 cctggcgaag ggcgtctccg accacatctc cggaggcgcg gtacgccaga cggtcgtgga
    17641 gtggcggagc cagttcctca tcgtgaccgc ggcaggcgag cgcgcctgcc tggcggtcct
    17701 gtgcgcccag caggccgaca tcgggctggt ggcgtacgag atggcgatgc tggtggcccg
    17761 cgtcggccag tacctcacct ccggcgcccg caacgccgga gccgccgccg ggagcgaccg
    17821 gtgagaggcg gcacggacgg gccgaccgac gagcactggg tggatccgga gatcatccgg
    17881 ccctacgtgg tcacccgtgg ccgcacgcag cccgcgcacg gccggttcga cctgatctcc
    17941 atggccctcg ccgtaggccc gacgccgggc cccgacgccg ggctcgaccc cgagcatctg
    18001 cgcatcctgc agctctgccg cgagcccaag tccgtcgccg agatcgccgc gtacctcgat
    18061 ctgccggccg gcacgatccg ggtgctgctc ggcgacctgt tcgaccgaga gctcgtctcc
    18121 gcgcaggaac cacaatccga ggtggacatg cacgacatga agatgtacag ggcggtgctc
    18181 gatggtcttc gctcgctctg agcgtccgcg cctgccgacg gcgatcaaga tcctggtcgc
    18241 gggcggcttc ggcgcgggca agacgacgat ggtgggcgcc gtctccgaga cccggccgct
    18301 gcgcacggag gaggtgctga ccgaccgcgg gatcggcgtc gacgacctca cctcggtgga
    18361 ggccaagcgc accaccactg tggcgatgga cttcggccgc atcaccctgg gcaacgacta
    18421 cgtcctgtac ctgttcggca cgcccgggca ggagcgcttc tggttcgtgt gggacgagct
    18481 ggccgagggc tcgctgggcg cggtcatcct ggccgacacc cggcgcctgg ccgactgctt
    18541 cccctcggtc gactacttcg agcggcgggg cacgccgttc gtggtggcgg tcaactgttt
    18601 cgagggggcg ccgacgttcg agctggagga ggtacgcctg gcgctgcagc tcagcccctc
    18661 catcccgatc atcatgtgcg acgcccgcaa gcgggagtcc agccgggagg tgctgatcac
    18721 gctggtcaag cactcggccc ggctccgcgc cgaaccggtc ggcagctagc tcccgcgcat
    18781 cccggccatc gccaccctca tccgtggatc agggtggcga tgtcgtggaa cagccggtcg
    18841 tgcgcggcgg ccgccgctgc ggaggtcagg tccatgttct ggatgaaccc gtgcgccagg
    18901 ccccgctcct gccggtgcgt cacccgcgcg ccggcctccg cgaggcggcg ggcgtaggcg
    18961 tcgccctcgt cgcgcagcgc gtcgtgctcg gcggtcacga ccaggccgcc gggcatgccg
    19021 gacaggtccg ggctcagcag cgggctggcg gcgacgcgat cggcggggtc gggcgcccac
    19081 tgggcgatgg cccaggtgag gaaatcggcg tcgagcgcgt atccgctgcc cttttcggcg
    19141 acgctggcct gggagagcgt caggtcggtg ttcggacata tcaagatctg tacggcgggc
    19201 agcgggtcac cggcgtcgcg gagacgcagg catgccatgg tcgccaggta gccgccggcg
    19261 ctgtcgcccg ccaccgccgc cgggcgcgac cagcgcacca ccgctgccac gtcgtcgatg
    19321 gccgccggat agggatgctc gggggcgcgc cggtagtcga cggccagcac ctcgacgtcg
    19381 catgcctcgg cgaggcgccg gcaggtgcgg tcgtgggtgt ccaggtcgcc catgacgaag
    19441 gcgccgccgt gggcgaacac catcagcggc cgcgcctgtt cgcggggccg gtagcggcgc
    19501 agcggcagcc cgccgggccc gtggaggtcc tccacgtgtg ccagtgcggg gccgagcggg
    19561 cgggcggcgg cacgccggcg ggcgctctcg cggagctcgg gtatctcagg ggtgatcatc
    19621 ggtgcgctcg tctcgtggtg ggcggtggcc aggaccgttc gatgcgggag cccggtgcgg
    19681 gaagccggtg ggcgaagtcg gggcgggaag tcggggcggg aggtgcggga ggtgcgggtg
    19741 gtgcgatggt gcgggtggtg cggggatgag cgtgccgcgg ggcccggacg ggaccccgcg
    19801 acacgctgtg gccgcgcggg tcgccgtccc gtcaggcggc gtcgagggcc gcggtgatcc
    19861 tgcgggccat gtcggtcagg gcgggaccgg gctcgccccg gtgggtccgg gccgctgcct
    19921 cgatggcgac gatgatagtg ctgcggaagg tgccggcctc cgccggagcc tgcttcctga
    19981 gcaggctcat ggtcgccgtc agggccggca gcacgtggtc ggcgatgtcc gccacggacc
    20041 tgccggtcag gtccatgccc gtcggctttc cggcgaggac gtgcccgacc aggccggtgg
    20101 cggaggtcag ggcgatggag ccggcggtgg cgatcttgtg gggttttccg gtggcgtcgg
    20161 tggcggccag cagcgtgacg gcgccgtggg cggcggtcct catggtgagt tcgtcctggt
    20221 cggtgagggt gatggacacg gtggtgtgct ccttcgcggt ggtacgcctg gtggcggcgc
    20281 ggtctcagtc gtcgatggcc tggtagaggg tggtccagaa gtcgtggatg aggtgcatgg
    20341 agtcgggggt ggaggcgccg acctgggtga gcaggatgcc ggtgaggtgg tgggcggggt
    20401 cggcgtaggt ggcggtgccg ctgccgccgt cccagccgaa ctggccgatg ggggcgtagt
    20461 cgccgcggta ggtgcgtacg gccatgccca ggccccagcc gccgtgctgg ccctggccgt
    20521 gggagatgtg gacgttgtcg acggccatgg cgtggcgggc ggcctgctga tcgggggtga
    20581 gccggttggt ggtcatcagc tcgacggcgg gccgggacaa gatccgcttg ccgtggtggg
    20641 tgccgccgtt gagcagcatg cggaagtagg cgtggtagtc gtcggcggtg gagaccagtc
    20701 ctccgccgcc gccctggaag gcggggggac ggctccagcg gccgtcctcg gcctcgtccc
    20761 agaccaggaa ctcgcccgtt tcggggtcgg gggcgtacag ggtgggcagc cggtcgatgt
    20821 gctcggcggg cacgtggaag ccggtgtcgc tcatgcccag ggggtcgagg atgcgctcgc
    20881 gcaggaactc ctcgaacggc cggccggtga cgcgggcgac cagcacgccg gccaggtcgc
    20941 tgctgatgtg gtactgccag cgatggccgg gctggtgcat gaggggcagt tcgcccaggc
    21001 ggcgcagcca ttcgtccggt tcgggcacct cgaccggcag gttgggggtc aggccgcgct
    21061 cgaagatcgc gttcaggatg ggggtgccga gcgaggtcat gtccatgccg aggccgaagg
    21121 tggaggtcag cacgtcgcgc acggtgatgg gccgatgcgc cggcacggtc tcctccagcg
    21181 ggccgtcgat ccgccgcagc acccgccggt cggcgagttc gggcagccac cgctcgaccg
    21241 ggtcgtccag ccgcagccgg cactcatcca gcagcaccat cgccgcggcg atcgagaccg
    21301 gcttggaggt ggaggccatc cggaagatcg tgtcccggcg catcgccgcc ccaccgtcat
    21361 gccgcatcgt ccccatcgcc tcgacatgcg tccgatcacc ccggctgacc agcgcgacca
    21421 gcccgggaat ccgcccccca tcgacatacc gggccagcac gtcacgcagc ctgcgcagcc
    21481 cggactccga gaagcccttg tcgccgttct ccatgatgaa atctccttcg cgcacagtgt
    21541 ccgatcgtca gagcccgtcc ccaccgggca tcgagaacgc tagatccggg cgtggcagaa
    21601 ggaatgagta aggtgactca tgatgtgtcg taggtagcgg ggatgcgcga tgttgcaggg
    21661 gcgggctgag gaggtccggg ccgtcgaggc tctcctcgcc gaggcgagat ccggggccgg
    21721 cggcgtcctg gtgatcaggg gcgagcccgg catggggaag tccgcgctcc tcgaccacgc
    21781 cgcgcgggcg gccgccgggg ccggcgtgct gcgcggggcc ggcgtggaga ccgaggtcga
    21841 gctgcccttc gccgccctcc acctgctgct gcggccggct ctcgaccggc tcgacgcgct
    21901 cccggcaccg caggccgcgg cgttgcgcgg ggtgttcggg ctggcgccgg tggcggggac
    21961 cgaccggttc ctggtcgggc tggccgcgct caccctgctg tcggagctgg ccgaggagcg
    22021 cccgctgctg gtcctcgtcg acgacgccca gtggctggac cgggcctcgg ctgaggctct
    22081 ggcgttcgcg tcgcggcggt tgcggtccga gggcgtcacc ctgctgatcg cggcgcgcga
    22141 cgaccgggac gccttccctg ccaccgggct gccggagctg cgcctcggcg ggctgccgcg
    22201 cgacgacgcc gagcgcctgc tcagcgacgg cctccccgcc cacctgcggg agcaggtgct
    22261 caaggaggcc gacggcaacc cgctggccct catcgagctg tccagggccg cgtgcgaggg
    22321 cgagtgggag ctcggcggga cgctgccgct cacgcaccgg ctccaggagg ccttcaccgg
    22381 ccagatccac cggctgccgg aacccgccag gaggctgctc gcggtggcgg ccgccgagga
    22441 caccggagct ctggggaccg tgctggccgc ggccggcgcg ctcggcatcc ccgccgacgc
    22501 gctggagccg gccgagcggg ccgggctcgt cacggtcacc ggcggcgtcg tacgcttccg
    22561 ccacccgctg ctgcgctcgg ccgcctacca gggagcgctc tcctcccagc gccgtgcgat
    22621 ccaccgggcg ctggccggat ccgtgagcgc cgaccggcgg gcctggcacc tggccctggc
    22681 cgcgaccggg cccgacgagc acatcgccgg cgctctggaa cgctctgccg agcaggccgg
    22741 ggcccgcctc ggctacgcgg ccatggcgac ggcctatgag cgcgccgcgt acctcagcac
    22801 cgaccagggt cgcatggccc gccggctggc ggcggcggcc ggcgcggccg gcgaggcagg
    22861 gcagtccggc cgtgcggcgg acctgagcga gcgggccgcg cagctgaccg gcgaccccgt
    22921 caccctggcc cggctcgcag agatcacctc gacggcggag ctcgaccggg ggtcgccgcg
    22981 gcgagcggcg agcgtcctca tcgacggggc ggcccccata gccgggaccg atccccggtc
    23041 ggccgcccgc atgctcgcgg ccgcctcgcg caacgcctgg gtcggaggcg acaccgcgct
    23101 gatcgcggag gcgtcacggc tgctcgaccg gctcggcctt cccccggagg acggtctcgc
    23161 cgcgctcacc cgcgggctcg ctcacatcca cggcggcgac ctcgagtccg ggtaccctct
    23221 gctggacggc ttcctccggc acgcctcgcc ggccgatgtc gaggggcagc tgacgctcac
    23281 ccatcccgtc ttcgtcgccg gccgcctcga tctcgcccgt gacctgtcca cctccctggc
    23341 cgcccgctgc cgcgcggagg gccgcatccg gctgctcccc ttcgtcctcg accagctcgc
    23401 ctacagccgg ctcatgaccg ggcgccaccg cgacgcgcgc gacagcgcgg cggaggcgct
    23461 ccagatcgcg ctggacaccg gccaggccca ccccaccacg gggctgcgcg gcatgctggc
    23521 ctggctggcc gccgtcgagg gcgacgagga gcgctgccgc gccatggccg aggagggcgt
    23581 caggttcgcg ctcgcccgcg gctcctggcc cgtcgacctg ctcgcgacct gggcgctggc
    23641 catgctggac ctgacccagg gacgcgacca ggccgcgctc gaccgcctcc agatgcgccc
    23701 tcgcggctcg tcgcacttct ccctccgggt cgtcgtcgac gaggtcgagg ccgccgtacg
    23761 gctgggcacg cccgaacggg tgctggagcc gctggcgctc ttccggcgct gggcggagct
    23821 gtcgggcgag gcgtgggcgg gcgccctggt cgcgcgctgc cacgggctga tccacgattc
    23881 ggaggagcac ttcacccggg cgctggatct gcaccggctg gcggagcagc cgtacgagca
    23941 ggccagaacg cacctggcct acggcgagtg gctgcgccgc cgtcgccgca aggccgaggc
    24001 ccgcccgcac ctgcgccacg cccgcgagtc cttcgagcgc ctggacgccc ggccctgggc
    24061 cgatcgggca gccgccgaac tgcgcgccgc cggcgaagcg ccgcccaccc gccgccgcgc
    24121 cgaccggggc gccgcgctga ccgcccagga actccaggtc gtacggctgg ccgccaccgg
    24181 cgccaccaac cgcgacatcg ccgcccacct gctcctcagc ccgcgcaccg tcgggcagca
    24241 cctctacaag gccttcccca agctgggcgt cgtctcccgg acggagctgg cccggctgga
    24301 gctcgaccgg ctctagcaac gagcccgttc agggggtgag ccgccgggcg cgcccgtgcg
    24361 gagaacctcc tcggcgtgcc gccgtgcctg cccgcccgcg atgacctgct cgcacgccag
    24421 cagcagcacc ccggcgctcc aggcgtgcga cagcgtgagg tacatgccct tgggctggaa
    24481 gcagtccgtc tggtagtagc gctcggtgat catgccccgg taggcgttga gctcgccgtc
    24541 ggcggccggg atcagctggc ggaagcagtc gagggtctcc cacgcccggt ccgcgtagta
    24601 cgggtcgccg agggcccgcg acagctccac cagttcggcg gtgcagacca gcccgtaggc
    24661 gtgcaggtgc tggttggacg gcgacgcctg gtccgcgccg cgcgtcgcga agccgtacac
    24721 gcccagcggg gtgcgcggcc cgaagcgcac gttgtaggtg tagcggaacg tgagcatcca
    24781 gtcggcggcg cggcgggcca ggtcgagcca gcgcggcgcg cccgtggccc tgaagagggc
    24841 catgtacgcg agcacggccg cgtagccgtc ctccgaggtg ggtgcgaggt
//
