LOCUS       NZ_CP045572            21068 bp    DNA     circular CON 07-NOV-2024
DEFINITION  Nonomuraea phyllanthi strain WYY166 chromosome, complete genome.
ACCESSION   NZ_CP045572
VERSION     NZ_CP045572.1
KEYWORDS    RefSeq.
SOURCE      Nonomuraea phyllanthi
  ORGANISM  Nonomuraea phyllanthi
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Streptosporangiaceae; Nonomuraea.
REFERENCE   1  (bases 1 to 11273186)
  AUTHORS   Ou,Y. and Wu,Y.
  TITLE     Nonomuraea nitratireducens sp. nov., a new actinobacterium isolated
            from Suaeda australis Moq. rhizosphere
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 11273186)
  AUTHORS   Ou,Y. and Wu,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-OCT-2019) School of Life Sciences and Biotechnology,
            Shanghai Jiao Tong University, Dongchuan, Shanghai 200240, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. Aug-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 160.0x
            Sequencing Technology             :: PacBio RSII; Illumina NextSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009497075.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 06:36:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,403
            CDSs (total)                      :: 10,325
            Genes (coding)                    :: 10,209
            CDSs (with protein)               :: 10,209
            Genes (RNA)                       :: 78
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 116
            CDSs (without protein)            :: 116
            Pseudo Genes (ambiguous residues) :: 0 of 116
            Pseudo Genes (frameshifted)       :: 22 of 116
            Pseudo Genes (incomplete)         :: 104 of 116
            Pseudo Genes (internal stop)      :: 8 of 116
            Pseudo Genes (multiple problems)  :: 13 of 116
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:05:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3909844
            Orig. end                         :: 3930912
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP045572.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21068
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="11"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21068
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21068
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11068](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11068)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(137..997)
                     /locus_tag="GBF35_RS17960"
                     /old_locus_tag="GBF35_17925"
     CDS             complement(137..997)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541660.1"
                     /locus_tag="GBF35_RS17960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_17925"
                     /product="xanthine dehydrogenase family protein subunit M"
                     /protein_id="WP_153262307.1"
                     /transl_table=11
                     /translation="MDFLRPTTWDEALAAKADRPDAVPIQGGTDVMVEINMDVRRPAAL
                     LDLGRVAELREWAMVDGMCRVGAAVPYATVIEELGGPLPGLAQAARTVGSPQIRNRGSV
                     GGNLGAASPAGDSHPPLLAADAVVEVASRERGVRMVPATEFYLGVKRNALEPDELIRAV
                     HVRPATGPQYFSKVGTRNAMVIAVCSFAIALHPDRRRVGTGIGSAAPTPRRALEAEELL
                     AEELDWTAPLDPALVRRFGELCAAAAAPIDDVRGTAAYRVHAVGVMARRTLTWAWNDHF
                     GRRAA"
     gene            complement(1004..1864)
                     /gene="pucL"
                     /locus_tag="GBF35_RS17965"
                     /old_locus_tag="GBF35_17930"
     CDS             complement(1004..1864)
                     /EC_number="1.7.3.3"
                     /GO_function="GO:0004846 - urate oxidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0019628 - urate catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pucL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541659.1"
                     /locus_tag="GBF35_RS17965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_17930"
                     /product="factor-independent urate hydroxylase"
                     /protein_id="WP_153262308.1"
                     /transl_table=11
                     /translation="MTVKLGPNRYGKAEIRLVRVVRDGPVHHVKDLNVSTSLSGDMEAV
                     HLTGDNAAVLPTDSQKNAVYALAGKHGVGQIEDFALLLARRFVESQPTIHHARVGIDEY
                     AWRRGGPHSFVRDGGEVRTCVVHHDRDGRSSVVSGLKDLVLMNTTGSEFHGFIVDDYTT
                     LQPTTDRVLATAVAAHWRHAGDTPDHGASYERVRECLLEAFAGTHSRSLQQTLYAMGER
                     ALTACPEICEIRLAMPNKHHFAVDLSPFGLPNENEVFHAADRPYGLIEGSVLREDAPDA
                     GFAWE"
     gene            complement(1865..2164)
                     /gene="uraH"
                     /locus_tag="GBF35_RS17970"
                     /old_locus_tag="GBF35_17935"
     CDS             complement(1865..2164)
                     /EC_number="3.5.2.17"
                     /GO_function="GO:0033971 - hydroxyisourate hydrolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006144 - purine nucleobase metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="uraH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013151771.1"
                     /locus_tag="GBF35_RS17970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_17935"
                     /product="hydroxyisourate hydrolase"
                     /protein_id="WP_153262309.1"
                     /transl_table=11
                     /translation="MSFSTHVLDAVTGLPAQGLRVRLEHEGRVVAEGRTDGDGRIAGWS
                     PGAGVHRVIFDTGSYLEDTFYPEVVVTFTITDPERHHHVPLLLSPYAYSTYRGN"
     gene            complement(2161..2661)
                     /gene="uraD"
                     /locus_tag="GBF35_RS17975"
                     /old_locus_tag="GBF35_17940"
     CDS             complement(2161..2661)
                     /EC_number="4.1.1.97"
                     /GO_process="GO:0019628 - urate catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="uraD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541657.1"
                     /locus_tag="GBF35_RS17975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_17940"
                     /product="2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline
                     decarboxylase"
                     /protein_id="WP_153262310.1"
                     /transl_table=11
                     /translation="MRDKLTDFNARSPADAEKALLSCCASRAFAAKVAALRPYRDLVEL
                     SAAAEAAVRDLAWDDVLEALEAHPRIGERATGGGRAAAWSRQEQSGVDDELREPLAEGN
                     RVYEERFGHVYLVCATGLSAEDMLERLRARLRNDAATEREVVRDELAGITRLRLGKLMK
                     EGT"
     gene            complement(2825..4852)
                     /gene="pknB"
                     /locus_tag="GBF35_RS17980"
                     /old_locus_tag="GBF35_17945"
     CDS             complement(2825..4852)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pknB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889483.1"
                     /locus_tag="GBF35_RS17980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_17945"
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_139633116.1"
                     /sec_met_domain="Pkinase (E-value: 5.1e-51, bitscore:
                     172.8, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTTTADPLVGRLVDGRYRIESRIARGGMATVYLALDIRLDRTVA
                     LKVMHRSLAEDPAFVRRFIGEAKAVARLSHPNVVHVFDQGTDNDIVYLSMEYVPGRTLR
                     DILRERGPLPAREALEIMIPVLAALGAAHQAGMVHRDVKPENVLMTEDGRVKVVDFGLA
                     RAIEATNQTRTGVLIGTVGYMAPEQVTLGAADVRSDVYAAGIMLFELVTGRQPYDGQTP
                     MAVAYRHVHDTVPPPSSLVAEVPQLIDTLVAQATAREPADRPADATAMLVVAVDTHRML
                     PRTTDPSAPRPQSPMTSAASSMPHSPMGPGAPSTPYGTASSPHGAPSTPHGAASMPHAT
                     ASMPQAAPSVPQAAPAHTLIQPREEAPRRRGGFRPNWFLVALAAVMVVAVGLTGWYFAQ
                     PETVTVPDLVGKNLELAKRNAVAAGLKVKEAAGLNDEEMAAGLVLRTDPLAETEVEKGT
                     TITLVPSLGPKRIVVPKTAGMTGDDARAAIAAAGLTVGVVKRLANEEVERDKVIRTSPR
                     VGEKVREGAKVDIYVSAGLLMPDVSGMPKDEAASYLGNQGFQVQVNEVDDDAEPCTVIA
                     QTPKAKSEVDRGAQASITVARCQTDFWDWFRGDNEARDDQQFVVVPGVIGKNAKDAKAE
                     LEAQGFKVRVQRLGNRGVVQFQRPLPNSERPQGSTVYLWQ"
     gene            complement(5056..5811)
                     /locus_tag="GBF35_RS17985"
                     /old_locus_tag="GBF35_17950"
     CDS             complement(5056..5811)
                     /EC_number="2.8.1.10"
                     /GO_function="GO:1990107 - thiazole synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541669.1"
                     /locus_tag="GBF35_RS17985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_17950"
                     /product="thiazole synthase"
                     /protein_id="WP_139633117.1"
                     /transl_table=11
                     /translation="MDELIIAGEKFTSRLIMGTGGAPSLEVLDQALAASGTELTTVAMR
                     RLDPGARGSVLDVLRKRDIKVLPNTAGCFTAGEAVLTARLAREALGTNWVKLEVIADER
                     TLLPDPIETFDAAERLVADGFVVLPYIGDDPALARRLEQAGCAAVMPLGAPIGSGLGIR
                     NPHNIELIVEAASVPVVLDAGIGTASDAALAMELGCDAVLLATAVTRAQRPDLMAEAMK
                     GAVTAGRQARLAGRIPRRRYAEASSPMTP"
     gene            complement(5804..6004)
                     /gene="thiS"
                     /locus_tag="GBF35_RS17990"
                     /old_locus_tag="GBF35_17955"
     CDS             complement(5804..6004)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541670.1"
                     /locus_tag="GBF35_RS17990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_17955"
                     /product="sulfur carrier protein ThiS"
                     /protein_id="WP_139633118.1"
                     /transl_table=11
                     /translation="MIVTINGAAHEVADGTTVAQAVRTLTAATTGVAVAVNDEVVTRSS
                     WETTALSDRDRVEVLTAVQGG"
     gene            complement(6001..7410)
                     /locus_tag="GBF35_RS52630"
     CDS             complement(6001..7410)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017622291.1"
                     /locus_tag="GBF35_RS52630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_228011271.1"
                     /sec_met_domain="DAO (E-value: 3.9e-36, bitscore: 124.6,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVIVGGGVVGLSAAWRLARAGRPVTVVDPAPASGASHAAAGMLA
                     PVSEVTYTEAPLLRLGVASLRRWPAFAAELAADAGLAGTRDLDLRADGTLDVAFGSDDL
                     AALDELAAYMEKLELPVERLTGRECRRLEPMLAPSVRGGLLAPGDAWVDPRRVTAALLA
                     ALDRLEVPLVRARVAELLRDGDRVVGVRLEPPGDTAPSPGTTAPAATGEGGSGLAGQGT
                     SGLAGPSGATGQAAGAWDGWSAVAAEGVNAGAGEGAGAGSGERAGHGGAWEAGRTGTGT
                     GTRAGGRTAARAGIAGGPGEIRGERVLLAAGAWSAGLAEVPVRPVKGQIMRLRSPQPLL
                     TRCVRGTVHGTPVYLVPRGDGELVVGATQEELGFDRRVTAGGLYELLRDARELVPGVTE
                     LEVADVVAGLRPGTPDNLPLVGPSGTPGLALATGHFRGGVLMAPLTADILLGEEGELAA
                     LCAPGRFREIS"
     regulatory      complement(7400..7515)
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(7430..7443)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.18"
                     /tool="antismash"
     gene            7569..8738
                     /locus_tag="GBF35_RS18005"
                     /old_locus_tag="GBF35_17970"
     CDS             7569..8738
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541672.1"
                     /locus_tag="GBF35_RS18005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_17970"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_317619836.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.2e-46, bitscore:
                     157.7, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVNHVVVVGAGLAGVRTVEALRARGFGGRITLIGEERHRPYDRP
                     PLSKAVLFGDADTSYVGTDLDAIEVDFRPGVSAKSLREGVVETTEGEVRYDGLVIATGA
                     EPIRLPGDGPQHVLRTLDDAHELRAMLVPGAQVAVIGAGWIGAEVATAAGRAGCSVTVI
                     ESGPAPLATAVGAGIGARTQHWYDGIDLRLGTMVDSVDEGGVRLVGGEFVEAHVVVTGI
                     GVRPAVEWLTGADIDLHNGVVVDEHLRASLPNTVAVGDCAAWWSRRWETRLRVEHWDTA
                     LNAPEVAAASLLGEDVAYDPVPYFWSEQFGHMVQYAGHHPAGERLIYRGDPEGKWSAVW
                     LTAGDVPAAVLAVDRPRDLVQGRRIIAAGHRVDAERLVDPDVPLRDCVV"
     gene            8769..9143
                     /locus_tag="GBF35_RS52635"
     CDS             8769..9143
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541673.1"
                     /locus_tag="GBF35_RS52635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_226899879.1"
                     /transl_table=11
                     /translation="MTLSVAQIDRETEQLIDEWLTLPEVATRLDLSIGRAKQLLKDHKL
                     LGVRRESGGPQVPAVFLDGKDVMKGLPGTLTVLQDAGYDDVESLRWLFTPDDSLPGSPI
                     QAIKAGRHTEVKRRAQALAF"
     gene            9121..9771
                     /gene="thiE"
                     /locus_tag="GBF35_RS18010"
                     /old_locus_tag="GBF35_17975"
     CDS             9121..9771
                     /EC_number="2.5.1.3"
                     /GO_function="GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1280: thiamine-phosphate pyrophosphorylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541674.1"
                     /locus_tag="GBF35_RS18010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_17975"
                     /product="thiamine phosphate synthase"
                     /protein_id="WP_228011272.1"
                     /transl_table=11
                     /translation="MPKPSLSEARLYLCTDGRRDRGDLAEFLDSVLAGGVDIIQLREKG
                     LEARDELALLEVFRDACDRHGKLLAVNDRADIAFAARPDVLHLGQDDLPVTVAREILGD
                     DIVIGRSTHSTAEASAAAVEPGVDYFCCGPIWPTPTKPGRPAPGPPLLRHAAALESPRP
                     WFGIGGIDLANLDEVMSYGARRVVVVRAITDAEDPGAAAAEFAKRLSSAPPPP"
     gene            complement(10001..11068)
                     /locus_tag="GBF35_RS18015"
                     /old_locus_tag="GBF35_17980"
     CDS             complement(10001..11068)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889490.1"
                     /locus_tag="GBF35_RS18015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_17980"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_193318616.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.2e-45, bitscore:
                     155.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTDAARMDTLRTQVERALGEFVERRLPASGESEFAPLRTAADEL
                     LSGGKRLRPAFCYWGWRGAGGTDVPGIFTAAASLELLQASALVHDDVMDKSDLRRGMPS
                     AHRRFQALHEKSGWHGSGEQFGEGAAILLGNLLLIWSGEMWRNSGLPPESLAAAQPVHD
                     HMRSELMCGQYLDLLEQAHGENTFESALRVALFKSGKYSVEQPLRLGLVLAAGEVAPWM
                     DELCTGYGTRVGIAFQLRDDILGVFGDPAQTGKPAGDDLREGKRTMLVARTLAAASPGD
                     AATVRHLLGDPDLDGRGVDTLRQIIDDTGALQECENLIGDYLGEALAALDQAPVTAEAR
                     SALTDLAIAATSRKT"
     gene            11234..12214
                     /gene="metF"
                     /locus_tag="GBF35_RS18020"
                     /old_locus_tag="GBF35_17985"
     CDS             11234..12214
                     /EC_number="1.5.1.20"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011291497.1"
                     /locus_tag="GBF35_RS18020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_17985"
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="WP_153262313.1"
                     /transl_table=11
                     /translation="MALGRPSVLPDRVPTVRDLLAAGGRSFSFEFFPPKTDEGARQLWK
                     AIRELESLRPTFVSVTYGAGGSTRDRTVGIVERIAHDTTLTPVAHFTAVNHSIRELRHL
                     VGRFADAGVRNILAVRGDPPGDPMAEWVQHPDGVLYSEELVRLIRQAGDFCVGVAAFPY
                     KHPRSPSIDADTEYFVQKCRAGADYAITQMFFRAEDYLRLRDRVAARGCDTPIIPCIMP
                     VTQMSTIARSEQLSGAPFPPEVAARFEEVADDPEAVRRLGIEHGAELCRRLLDEGAPGI
                     HFITFNRSSASREVFQRLNVPSSVTAGPAGRHPLPVAGGLQGDAR"
     misc_feature    complement(12600..12615)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.13"
                     /tool="antismash"
     gene            12646..13989
                     /locus_tag="GBF35_RS18025"
                     /old_locus_tag="GBF35_17990"
     CDS             12646..13989
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.5"
                     /locus_tag="GBF35_RS18025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_17990"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_153262314.1"
                     /transl_table=11
                     /translation="MITAVVMTILCLSISGLILMRVHDERTMERNHLNHDAAMRAAALL
                     ARGDLPPVHADPSVTALQVIDPTGRIVSTSPSMEGRPPLASFAPPPGRLGAERTLCRVP
                     GSGDACLLVSVQRAPRSHGDWMIYAAAPAYPWYVSGRLLAPLLLGCALIVAFTTLGARR
                     IVITSLRPVEAIRAKLSKITTTELGHRVPVPQPRDEIHDLAGTVNTTLDMLDAALTRER
                     RFTADASHDLRSPVTAMRTQVEEALLHPDETDWPAVARALLASLERLHAIVADLMELRR
                     LDADAGAPMMPVDLNELIVRELARRPQGKTIVSDCRPALVRGDRVQLLRLLTNLLDNAE
                     RHATSTVHVTLHCEQGEVALVVHDDGSGIPVHQREVVFQRFARLDAARNKDAGGSGLGL
                     PIAREIARHHGGTLTIEDSSRGARFVARIPLYRPPHRPGTIRGHLDPA"
     gene            complement(14282..14842)
                     /locus_tag="GBF35_RS18030"
                     /old_locus_tag="GBF35_17995"
     CDS             complement(14282..14842)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131597.1"
                     /locus_tag="GBF35_RS18030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_17995"
                     /product="N-acetyltransferase"
                     /protein_id="WP_139633123.1"
                     /transl_table=11
                     /translation="MIEFRGAGPAEFAERLETVIDIYTAAMKPPADQINGRKTIMRNHA
                     TYPHFQCYFAELRDSSLSSPVTVGFAYGFRGAPGQWWHDVVLRAVTDRLGEEAANAWMG
                     YVFELAEIHVHPDHQSQGIGRAMIRTLCAGRPERSAILSTHDQPTAARHLYASMGFTDL
                     LTRFVFPGGYEDYAIVGRPLPLT"
     gene            complement(14853..15329)
                     /locus_tag="GBF35_RS18035"
                     /old_locus_tag="GBF35_18000"
     CDS             complement(14853..15329)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131598.1"
                     /locus_tag="GBF35_RS18035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_18000"
                     /product="YbaK/EbsC family protein"
                     /protein_id="WP_139633124.1"
                     /transl_table=11
                     /translation="MPEKLPSNAVVVQSALRELGAGGEIVVLPEKAPTAATAAAQLGCE
                     VGAIANSLIFDADGAPLLVLTSGAHRVDVELIARTVGVGKVRRATPEFVRAATGQPIGG
                     VAPVGHPAPVRTLVDNWLSKHEVVWAAGGHPLTVFPTTFDELVRITGGAAVDVE"
     misc_feature    15329..15342
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.64"
                     /tool="antismash"
     misc_feature    complement(15395..15408)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.4"
                     /tool="antismash"
     gene            15452..16282
                     /locus_tag="GBF35_RS18040"
                     /old_locus_tag="GBF35_18005"
     CDS             15452..16282
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889495.1"
                     /locus_tag="GBF35_RS18040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_18005"
                     /product="L,D-transpeptidase family protein"
                     /protein_id="WP_139633125.1"
                     /transl_table=11
                     /translation="MAALLTAGAVALSGCGTQAPQRLTTAAPAAATAQAAPAATAASPS
                     VTPGAAGARSGPAATVTAPRKTLKLGAKGEPVEWLQKRLIQLGYRPGRVDGRYGNTTLA
                     AVWAFQKVNDIRPTSTIAKRTWEALETPKAPRVLVKNGRPTRAEVNLTKQIMVMYVDGE
                     AKLITHISSGSGIPYCETASWQGKRQRFCGSATTPTGNYRTTWRVHGWHRSYLGQLYNP
                     IFFNGGIALHGALSVPLYPASHGCVRMPMNVAEVLPGMLGKGVPVHVRGKFRRA"
     misc_feature    complement(16311..16328)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.98"
                     /tool="antismash"
     gene            16395..18128
                     /locus_tag="GBF35_RS18045"
                     /old_locus_tag="GBF35_18010"
     CDS             16395..18128
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GBF35_RS18045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GBF35_18010"
                     /product="hypothetical protein"
                     /protein_id="WP_153262315.1"
                     /transl_table=11
                     /translation="MTTVLTVSAPAPARRSRLRWLLAAGWVAHVVLRLWLYRYHAGPVA
                     NPDETGYLLAARWLAGGPGADLSGSTFYQGGYPLLLVPIFRLTSDPVLAYRLVVVAGSM
                     AAAGAYPLAYLLLRRFGVGRRVALVTAFVAGLSPALLVFPGLALADAILPALVLAWLLA
                     VHDLVAYGSARAGAAAGALSAFAMAAHLRGTVLLAVCVLVAVAAMSSRREPRVRLRRAV
                     PSSRPWEALYRRVRAMAYRRRAALVATAVAGVVAAAGQALNGPLAAALYPGGTRDLSGL
                     LLTRLTSADGQAWALSGAAGQLWYLVAGTWGLAGVGLAGAAALLVRRSAPYPHRVLAAA
                     LLLTTLGIAYASSAALPDEHRVGNYVYGRYLACVAVAWTLAGLVALLKGGRRAVVRLAL
                     AAAALTAATGGVAAWYAGDRLRRYHFIAFDFPEVIFLTGDGDSLDLLSASVPALIMLSC
                     LVGVAFVTTGRGRILVVGVLALIDMAFAAGQAPARPPGADWLPDPPLGRVAVDRRVRWN
                     LWVPLAYRVSWTEIELYDGGPPDGACTAVVPYGTAPPPGWAATGRGGAGTGWTSWSNER
                     C"
     gene            complement(18125..18646)
                     /locus_tag="GBF35_RS18050"
                     /old_locus_tag="GBF35_18015"
     CDS             complement(18125..18646)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GBF35_RS18050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GBF35_18015"
                     /product="hypothetical protein"
                     /protein_id="WP_153262316.1"
                     /transl_table=11
                     /translation="MTGSRRPITLYLLALGPVLAATYAGANLVAIKAAVRAQVASPEWE
                     GALPGPDEMTALGTDVWRVVLMTALLAGALAVAYAVIGLLLRRGSRRRTFLFVLSGVLI
                     VPYALAVFVALLNPVAGLAALYDSPGFAAGLPGWQAGTVVLLVVAALLQAIGLSAATGE
                     GRRALAAESG"
     gene            complement(18693..19313)
                     /locus_tag="GBF35_RS18055"
                     /old_locus_tag="GBF35_18020"
     CDS             complement(18693..19313)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1215: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012892714.1"
                     /locus_tag="GBF35_RS18055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_18020"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_139633128.1"
                     /transl_table=11
                     /translation="MVQSGGAGLRERKKQRTRRALVEAAFRLFDEKGYEETTLAEIAAE
                     AEVSTRTFFSYFASKEDVVFYDSARRMDLAVATLAGRAPGESPADVLRRLVRDSMCWLT
                     TYEEFSFEDAGLRLRLVLKEPTLQARALMMLIESQVRLARALHESYPDELGPVEAAAAV
                     GAVFGAVKLAIIANMDSGSSVEDMAETARRAAELTLSGLCSLG"
     misc_feature    19352..19368
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 20.14"
                     /tool="antismash"
     gene            19410..20591
                     /locus_tag="GBF35_RS18060"
                     /old_locus_tag="GBF35_18025"
     CDS             19410..20591
                     /EC_number="1.14.-.-"
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016712 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen, reduced flavin or flavoprotein as one
                     donor, and incorporation of one atom of oxygen [Evidence
                     IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541682.1"
                     /locus_tag="GBF35_RS18060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_18025"
                     /product="cytochrome P450"
                     /protein_id="WP_153262317.1"
                     /sec_met_domain="p450 (E-value: 2.5e-21, bitscore: 75.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDVTFPIARQRPLDPPDEATELRQRAAMHRMTYADGHRGWLVTG
                     YSAARAILAHPHFSNRAEVSHPPIPGRFERLRTKTPPGFFIRADAPEHTRYRKLLTGQF
                     TVRRMKALEPRIEEITNACLDDMAAAGGPVDLVQAFALPIPSLVICELLGVPYADREQF
                     QEDTKLLVNLETKAEESIAALGRSMAYLAGLIKRKREEPADDLLSGLIEGGELDDEELT
                     GVGFLLLVAGHETTANMLGLGTYALLTNPDQLAAMRDDPSVVDNGVEELLRYLTIVHLG
                     PVRTALEDVEIEGTTIRAGESATIHLPSVNRDAERFPGGDRLDLARPATGHMSFGHGIH
                     QCLGQQLARTEMRIAYPALLRRFPGLRLAVTPEEVPMRSDMSIYGVHRLPVTW"
     gene            20598..20789
                     /locus_tag="GBF35_RS18065"
                     /old_locus_tag="GBF35_18030"
     CDS             20598..20789
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1265: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017536827.1"
                     /locus_tag="GBF35_RS18065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBF35_18030"
                     /product="ferredoxin"
                     /protein_id="WP_153262318.1"
                     /transl_table=11
                     /translation="MEIKADTTVCIGAGMCALTAPQVFDQSEDEGTVVLLQKVPPQELE
                     EAARRAVTLCPSGAISIV"
     misc_feature    20867..20882
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.11"
                     /tool="antismash"
     misc_feature    complement(20868..20881)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.74"
                     /tool="antismash"
     misc_feature    20907..20922
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 25.32"
                     /tool="antismash"
     misc_feature    complement(20908..20921)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.64"
                     /tool="antismash"
ORIGIN
        1 ccgcactcgc cctgctcgca ggcgttcttg gagccgggca gccccatccg ctcgcgcagc
       61 acgtacagga ggctctcgcc ctcccagacg tggtcggcgc tctcctcgcg gccgttcacg
      121 gtgaacgtga cacgcatcag gccgccctcc ttccgaaatg gtcgttccag gcccaggtca
      181 gcgtccggcg cgccatcacg ccgacggcgt gcacccggta ggcggcggtg ccgcgcacgt
      241 cgtcgatcgg cgcggcggcg gccgcgcaca gctccccgaa ccgcctgacc agcgccgggt
      301 cgagcggcgc ggtccagtcg agctcctcgg ccagcagttc ctcggcctcc agcgcccggc
      361 gcggggtggg cgcggcggag ccgatccccg tgccgacccg ccgccggtca ggatggagcg
      421 cgatcgcgaa cgagcacacc gcgatcacca tggcgttgcg cgtcccgacc ttggagaagt
      481 actgggggcc cgtcgcgggc ctgacgtgca cggccctgat cagctcgtcc ggctccagcg
      541 cgttgcgctt gacccccagg tagaactccg tggccgggac catcctgacg ccccgctccc
      601 gcgaggccac ctcgaccacg gcgtccgccg ccagcagcgg cgggtggctg tcaccggcgg
      661 gggaggccgc gcccaggttg ccgccgaccg agccgcggtt gcggatctgg ggcgagccga
      721 ccgtgcgggc cgcctgcgcg agccccggca gcggcccgcc cagctcctcg atcacagtcg
      781 cgtacggcac cgccgccccg acccggcaca tgccgtccac catggcccac tcccgcagct
      841 cggccacccg ccccaggtcg agcagggccg ccggcctgcg cacgtccatg ttgatctcca
      901 ccatgacgtc ggtgccgccc tggatgggca ccgcgtcggg ccggtccgcc ttggcggcca
      961 gcgcctcgtc ccacgtcgtg ggccgcaaga agtccatgtc cgctcactcc caggcgaatc
     1021 cggcgtcggg tgcgtcctcg cgcagcacgc tgccctcgat cagcccgtac gggcggtcgg
     1081 cggcgtggaa gacctcgttc tcgttgggca ggccgaacgg ggacaggtcg acggcgaagt
     1141 ggtgcttgtt gggcatcgcg agccggatct cgcagatctc cgggcaggcg gtcagggcgc
     1201 gctcgcccat ggcgtacagg gtctgctgga gcgagcggct gtgggtgccg gcgaacgcct
     1261 ccagcaggca ctcccgtacc cgctcgtacg acgcgccgtg atcgggcgtg tcaccggcgt
     1321 gccgccagtg cgcggccacg gcggtggcga ggacgcggtc ggtggtcggc tggagggtgg
     1381 tgtagtcgtc cacgatgaag ccgtggaact ccgagccggt cgtgttcatc aggaccaggt
     1441 ccttcagccc cgacaccacg ctggagcggc cgtccctgtc gtggtggacg acgcacgtgc
     1501 gcacctcgcc gccgtcgcgc acgaacgagt gcggcccgcc gcgccgccac gcgtactcgt
     1561 cgatcccgac ccgggcgtgg tggatcgtgg gctgcgactc gacgaagcgc cgggccagca
     1621 gcagcgcgaa gtcctcgatc tggccgacgc cgtgcttgcc ggccagcgcg tacaccgcgt
     1681 tcttctggct gtcggtcggc aggacggcgg cgttgtcgcc ggtcaggtgc acggcctcca
     1741 tgtcgccgga gagcgaggtg ctgacgttga ggtccttgac gtggtgcacg ggcccgtcgc
     1801 ggacgacccg gacgagcctg atctccgcct tgccgtagcg gttggggccg agcttgacgg
     1861 tcatctagtt tcctcggtac gtggagtagg catacgggct gagcagcagc ggcacgtggt
     1921 gatgccgctc cggatcggtg atcgtgaagg tgaccaccac ctccgggtag aacgtgtcct
     1981 ccaggtagga gccggtgtcg aagatgaccc ggtgcacccc ggctcccggg ctccagcccg
     2041 cgatgcgccc gtcgccgtcg gtgcgcccct cggccacgac ccgtccctcg tgctcgaggc
     2101 gtacgcgcag gccctgggcg ggcaggccgg tgaccgcgtc gagcacgtgg gtcgagaagc
     2161 tcatgtcccc tccttcatga gcttgcccag ccgcagccgg gtgatcccgg cgagttcgtc
     2221 ccgcacgacc tcgcgctcgg tcgcggcgtc gttgcgcagc cgcgcgcgca gccgctccag
     2281 catgtcctcg gcgctcagcc cggtggcaca gaccaggtag acgtgcccga agcgctcctc
     2341 gtacacccgg ttgccctcgg ccagcggctc ccgcagctcg tcgtccaccc cggactgctc
     2401 ctgccgcgac cacgccgccg ccctgccgcc cccggtggcc cgctcgccga tcctcgggtg
     2461 cgcctccagc gcctccagca cgtcgtccca cgcgaggtcc cgcacggccg cctcggccgc
     2521 cgcggagagc tccaccaggt cacggtacgg ccgcagggcc gccaccttcg cggcgaaggc
     2581 ccgcgaggcg cagcaggaga gcagcgcctt ctccgcgtcg gccggggacc gcgcgttgaa
     2641 atcggtcagc ttgtcgcgca tgtcagaagt acacacatgc gcttcgtgcc cggtccatcc
     2701 gcaagaactc cgaagagccc gccctcatgg ccgggacttt tcgtgtcatg ctccaagccg
     2761 gtcggaccgg gcggcactac gacggggcct cgccggaggc agaccgcgct gccccgcggc
     2821 ggggtcactg ccagaggtag accgtgctgc cctgcggccg ctcgctgttg ggcagcggcc
     2881 gctggaactg caccacgccg cggttgccca gccgctgcac ccgcaccttg aacccctgcg
     2941 cctccagctc agccttggcg tccttggcgt tcttgccgat cacgcccggc acgaccacga
     3001 actgctggtc gtcgcgggcc tcgttgtcgc cgcggaacca gtcccagaag tcggtctggc
     3061 accgcgccac cgtgatcgag gcctgcgcgc ccctgtcgac ctcggacttg gccttgggcg
     3121 tctgggcgat gaccgtgcac ggctcggcgt cgtcgtcgac ctcgttgacc tgcacctgga
     3181 agccctggtt gcccagatag gaggcggcct cgtccttggg catgccgctg acgtccggca
     3241 tgagcagccc ggcactgacg tagatgtcga ccttggcgcc ctcgcgcacc ttctcgccca
     3301 cccgcggcga ggtgcggatc accttgtcgc gctcgacctc ctcgttggcc agccgcttga
     3361 ccacgccgac ggtcagcccg gcggcggcga tcgcggcgcg ggcgtcgtcg cccgtcatgc
     3421 cggcggtctt cggcacgacg atccgcttgg gaccgagcga ggggaccagc gtgatcgtgg
     3481 tgcccttctc cacctcggtc tcggcgagcg ggtcggtgcg caggaccagg cccgcggcca
     3541 tctcctcgtc gttgaggccg gcggcctcct tgaccttgag cccggccgcg acggcgttcc
     3601 tcttggccag ctccaggttc ttgccgacca ggtcggggac ggtcacggtc tcgggctggg
     3661 cgaagtacca gccggtcagc cccaccgcga ccaccatcac ggcggccagc gccaccagga
     3721 accagttggg cctgaacccc ccgcgccgcc tcggcgcctc ctcgcgcggc tggatcagcg
     3781 tgtgggccgg cgcggcctgc ggcacggagg gcgcggcctg cggcatcgag gccgtcgcgt
     3841 gcggcatcga ggccgctccg tgcggcgtgg aaggcgctcc gtgtggggag gaagccgttc
     3901 cgtacggcgt cgagggcgcg ccggggccca tgggggagtg cggcatcgac gatgcggcgg
     3961 aggtcatggg ggactgcggc cggggcgccg acgggtcggt cgtgcgcggc agcatgcggt
     4021 gcgtgtcgac ggccaccacg agcatcgcgg tggcgtcggc cgggcggtct gccggctcgc
     4081 gcgccgtcgc ctgcgcgacc agcgtgtcga tcagctgcgg cacctcggcc accagcgacg
     4141 acggcggggg cacggtgtcg tggacgtgcc ggtaggcgac cgccatcggc gtctggccgt
     4201 catagggctg ccggcccgtg accagctcga acagcatgat gcccgcggcg tagacgtcgc
     4261 tgcgcacgtc ggccgcgccc agggtgacct gctcgggcgc catgtagccg accgtgccga
     4321 tcagtacgcc cgtacgggtc tggttggtgg cctcgatcgc cctggccagg ccgaagtcga
     4381 cgaccttgac ccggccgtcc tcggtcatca ggacgttctc cggcttcacg tcgcggtgga
     4441 ccatgcccgc ctggtgggcg gcgcccagcg cggccagcac cgggatcatg atctcgagcg
     4501 cctcgcgggc gggcagcggg ccgcgctcgc gcaggatgtc gcggagcgtc ctgccgggca
     4561 cgtactccat cgacaggtag acgatgtcgt tgtcggtgcc ctggtcgaag acgtgcacca
     4621 cgttgggatg cgagagcctg gcgaccgcct tggcctcgcc gatgaacctt ctgacgaacg
     4681 ccgggtcctc ggcgagcgag cggtgcatga ccttcagcgc gaccgtccgg tcgagccgga
     4741 tgtccagcgc caggtagacg gtcgccatac cgccccgggc gatccggctc tcgatgcggt
     4801 agcgcccatc gacgagccgt ccgaccaggg ggtccgcagt cgtcgtatcc acccggttga
     4861 gtttacgggc gttttgccgc tgacagggtc gcgctgcccg aaaccgatgc cgagacgtgc
     4921 tcgtcgcgcc gtcccggctc cccgcacgtc actgccgtca cggtgccacc catgaggcgt
     4981 cacggcgtca tcggcgtcac actttcgtcg gcgtcacggc gtcacggcgt cacggcgtcg
     5041 tcggggtcgt cgatgtcacg gtgtcatcgg tgaggacgcc tccgcgtagc gcctgcgcgg
     5101 gatgcggccc gccagccgcg cctgccggcc cgccgtcacg gcccccttca tggcctccgc
     5161 catgaggtcg ggtcgctgcg cccgggtgac cgccgtggcc agcagcacgg cgtcgcagcc
     5221 cagctccatc gccagggcgg cgtcgctggc cgtgccgatg cccgcgtcga gcaccaccgg
     5281 caccgaggcg gcctccacga tcagttcgat gttgtgcggg ttgcggatcc cgaggcccga
     5341 gccgatcggc gcccccagcg gcatcaccgc ggcgcacccg gcctgctcca ggcggcgtgc
     5401 cagggcaggg tcgtccccga tgtacggcag caccacgaac ccgtcggcca ccagccgctc
     5461 cgccgcgtcg aacgtctcga tcgggtcggg cagcagcgtg cgctcgtcgg cgatgacctc
     5521 cagcttgacc cagttcgtac cgagcgcctc cctggccagc cgcgccgtca gcacggcctc
     5581 acccgcggtg aagcagcccg ccgtgttggg cagcaccttg atgtcgcgct tgcgcagcac
     5641 gtcgagcacc gagccgcggg cgcccgggtc gagccgccgc atggccaccg tggtcagctc
     5701 cgtccccgac gcggccagcg cctggtcgag cacctccagc gacggcgcgc cgcccgtgcc
     5761 catgatgagc cgggaagtga acttctcccc ggcgatgatc agctcatcca ccttgcaccg
     5821 ccgtcagaac ctccacccgg tcacggtcgc tgagcgccgt cgtctcccac gagctccgcg
     5881 tgaccacctc gtcgttcacg gccaccgcca cgccggtggt ggccgcggtc agtgtgcgta
     5941 cggcctgcgc cacggtcgtg ccgtcggcga cctcgtgcgc ggccccgttg atcgtcacaa
     6001 tcatgaaatt tcccgaaacc tcccaggcgc gcacaatgcc gccagctcgc cttcctcgcc
     6061 cagcaggatg tccgccgtca gcggcgccat cagcacgccg ccccggaaat ggcccgtggc
     6121 cagcgcgagc cccggagtgc cgctcgggcc cacgagcggc aggttgtccg gcgtgcccgg
     6181 ccgcagcccg gccaccacgt cggccacctc cagctcggtg acgcccggca ccagctccct
     6241 ggcgtcgcgc agcagctcgt agagcccgcc cgcggtcacc cgccggtcga accccagctc
     6301 ctcctgggtc gccccgacca ccagctcgcc gtcgccccgg gggaccaggt agacgggcgt
     6361 accgtgcacg gtgccccgga cgcaccgggt gagcagcggc tggggggagc gcaaccgcat
     6421 gatctgcccc ttgaccggcc gcacgggcac ctccgccagc ccggcactcc acgccccggc
     6481 cgccagcagc acccgctcgc ccctgatctc gcccggcccg ccggcgatgc cggcccgcgc
     6541 cgcggtccgc ccgcccgccc gcgtgccggt ccccgtcccg gtccgcccgg cctcccaggc
     6601 accgccgtgg cccgcgcgct ccccgctccc ggcccccgcg ccttccccgg cgcccgcgtt
     6661 cacgccctcg gcggcgaccg cgctccagcc gtcccaggca cccgcggctt ggccggtggc
     6721 tccgctcgga cccgcgagtc cgctcgtgcc ctggccggcg agtccgcttc cgccctcgcc
     6781 ggtggccgca ggcgcggtcg tgccggggga gggtgccgtg tcgccgggcg gctcaaggcg
     6841 taccccgacg acccggtcgc cgtcgcgcag cagctcggcg acgcgcgccc gcaccagcgg
     6901 gacctccagc cggtcgagcg cggcgagcag cgccgccgtg acgcggcgcg gatcgaccca
     6961 ggcgtcgcca ggagccagca gcccgccccg caccgacggc gccagcatgg gctccaggcg
     7021 gcggcactcg cgcccggtca gccgctcgac gggcagctcc agcttctcca tgtacgccgc
     7081 gagctcgtcc agcgccgcca ggtcgtcgga gccgaacgcc acgtcgagcg tcccgtcggc
     7141 tcgcaggtcg aggtcacgcg tcccggcgag ccccgcgtcg gcggccagct cggcggcgaa
     7201 ggcgggccag cgccgcagcg acgccacgcc cagccgcagc agcggcgcct ccgtgtaggt
     7261 gacctcgctg accggcgcca gcatccccgc ggccgcgtgc gaggcccccg aggcgggggc
     7321 cgggtcgacc acggtgaccg gacgccccgc gcgggccagc cgccacgccg ccgacagccc
     7381 gacgaccccg ccgcccacga tcacatccat ccgcgctccc ttcgccggca tgatccggat
     7441 caggtgtctt gcggtcgaag gcccgtcaag ccttcctctc agcccggtaa cggccggact
     7501 cccgcgcgtc tcaacgtcac cagcctacgg cctcggtgcg gcggcacgac accggccccg
     7561 ttatggtcat gaacgtgaac catgtcgtgg tggtaggagc gggcctggcc ggagtgcgca
     7621 ccgtggaggc gctgcgcgcc cggggcttcg gcggccggat cacgctgatc ggcgaggagc
     7681 gccaccgtcc ctacgaccgc ccgccgctgt ccaaggccgt gctgttcggc gacgccgaca
     7741 ccagctacgt cggcaccgac ctcgacgcca tcgaggtgga cttccgcccg ggcgtcagcg
     7801 cgaagtcgct gcgcgagggc gtcgtggaga ccaccgaggg cgaggtccgt tacgacggcc
     7861 tcgtcatcgc caccggcgcc gagccgatca ggctgcccgg cgacggcccg caacacgtgc
     7921 tgcgcaccct cgacgacgcc cacgagctcc gggccatgct ggtgccgggc gcccaggtcg
     7981 cggtcatcgg ggcgggctgg atcggcgccg aggtcgccac cgccgccggc cgcgccggct
     8041 gctcggtgac cgtgatcgag tccggccccg cgccgctcgc caccgccgtc ggcgccggga
     8101 tcggggcccg cacccagcac tggtacgacg gcatcgacct gcggctcggc accatggtcg
     8161 actccgtgga cgagggcggc gtgcgcctgg tcggcggcga gttcgtcgag gcccacgtcg
     8221 tcgtgaccgg gatcggcgtg agaccggccg tcgaatggct caccggcgcc gacatcgacc
     8281 tgcacaacgg cgtggtcgtg gacgagcacc tgcgcgcctc gctgcctaac accgtggccg
     8341 tcggcgactg cgccgcctgg tggtcgcgcc gctgggagac ccggctccgg gtcgagcact
     8401 gggacaccgc gctcaacgcc cccgaggtcg ccgccgcgag cctgctgggc gaggacgtgg
     8461 cctacgaccc cgtgccgtac ttctggtcgg agcagttcgg gcacatggtg cagtacgccg
     8521 gccaccaccc ggcgggggag cggctgatct accggggcga ccccgagggc aagtggtcgg
     8581 ccgtctggct cacggccggc gacgtcccgg ccgcggtgct cgccgtggac cggccgcgcg
     8641 acctcgtcca gggacgcaga atcatcgccg caggacaccg cgtcgacgcg gaacgcctgg
     8701 tagatccaga tgtcccccta cgagattgtg ttgtttgagc aagcacgcca tgtggtagtt
     8761 gtggtttcgt gacgctttct gttgcacaga tcgaccggga gaccgagcag ctcatcgacg
     8821 agtggctcac actccccgaa gtggccacgc gcctcgacct ttcgatcggg cgggccaagc
     8881 aactcctcaa ggaccacaag ctgctcggcg tgcgccggga gagcggcggg ccgcaggtgc
     8941 ccgcggtgtt cctcgacgga aaggacgtga tgaagggcct gcccggcacg ctgaccgtgt
     9001 tgcaggacgc cggctacgac gatgtcgagt cgctgcgctg gctcttcacc ccagacgact
     9061 cgctgccagg ttcgcccatc caggcgatca aggcaggccg tcacacggag gtcaagcggc
     9121 gtgcccaagc cctcgctttc tgaggcacgc ctctatctct gcaccgacgg ccgccgcgac
     9181 cgcggcgacc tggcagagtt cctcgactcg gtgctggccg gcggcgtgga catcatccaa
     9241 ctgcgggaga agggcctgga ggcgcgcgac gaactcgcac tcctcgaagt cttccgcgac
     9301 gcctgcgacc ggcacggcaa gctgctggcc gtcaacgacc gggcggacat cgccttcgcc
     9361 gcccggcccg acgtgctcca cctggggcag gacgaccttc ccgtgacggt cgcgcgagag
     9421 atactcggcg acgacatcgt catcggacgg tccacccact ccaccgccga ggcttccgcc
     9481 gcggccgtgg agccgggcgt cgactacttc tgctgcggcc ccatctggcc caccccgacc
     9541 aagcccggcc gcccggcccc cggcccgccg ctgctccggc acgcggcggc gctggagagc
     9601 ccgcggccgt ggttcgggat cggcggcatc gacctcgcca acctggacga ggtgatgtcg
     9661 tacggggcca ggcgggtggt ggtggtgcgc gcgatcacgg acgccgagga cccgggagcg
     9721 gcggcggcgg agttcgccaa gcgcctctcc tcggccccgc cgcctccctg acacgctgct
     9781 gcggaggccc ggaggcccgg aggccccacc tccgggcccc gatcatctgg gagccgcgcc
     9841 cgacgattcc gccctgcgcg gatccgcctc ggaacccacg cccgggggcc cgccgtcttc
     9901 gagcgcggtc tctgagtgct gcctgggagc gcggtctccg agtgcggtct tcgggtgcgg
     9961 tggagcgggt gcgggtggag cgggtgcctc ggacggggcg tcaggtcttg cgggaggtgg
    10021 ccgcgatggc caggtccgtc agggccgagc gcgcctcagc cgtcacgggc gcctggtcca
    10081 gcgccgccag cgcctcaccc aggtagtcgc cgatcaggtt ctcgcactcc tgcaacgccc
    10141 cggtgtcgtc gatgatctgc cgcagcgtgt ccaccccgcg cccgtccagg tcagggtccc
    10201 cgagcaggtg ccggacggtc gccgcgtcgc cgggggacgc ggccgccagc gtgcgggcga
    10261 ccagcatcgt ccgcttgccc tcccgcaggt cgtccccggc cggcttgccc gtctgcgccg
    10321 ggtcgccgaa cacccccagg atgtcgtcgc gcagctggaa cgcgatcccg acgcgcgtgc
    10381 cgtacccggt gcacagctcg tccatccacg gcgcgacctc gccggcggcg agcaccagcc
    10441 cgagcctcag cggctgctcc accgagtatt tcccgctctt gaacagcgcc acccgcagcg
    10501 ccgactcgaa cgtgttctcg ccgtgcgcct gctccagcag gtcgagatac tggccgcaca
    10561 tcagctcgga acgcatgtgg tcgtgcaccg gctgggccgc cgccagcgac tcgggcggca
    10621 ggccgctgtt gcgccacatc tcgcccgacc agatcagcag caggttgccc agcaggatgg
    10681 ccgcgccctc gccgaactgc tccccggagc cgtgccagcc ggacttctcg tgcagcgcct
    10741 ggaaccggcg gtgcgccgac ggcatgcccc tgcgcaggtc gctcttgtcc atcacatcgt
    10801 cgtgcacgag cgcgctggcc tgcagcagct ccagcgaggc cgcggcggtg aagatcccgg
    10861 gcacgtccgt gccgcccgcg ccgcgccagc cccagtagca gaacgcgggg cgcaaccgct
    10921 tgccgcccga cagcagctcg tcggcggccg tgcgcagcgg cgcgaactcg gactcgcccg
    10981 aggcgggcaa ccgccgttcg acgaactctc cgagggcacg ctccacctgg gtgcgcaggg
    11041 tgtccatgcg ggcggcgtca gtggtcatga cttgagcgta gtggccgagg ccccgaacca
    11101 ggctccgcag gtgtcccgaa acggcgctcg ggccgcggaa gcgcgacggc cgcggggcgg
    11161 tggcgagcgt ggggcggtgg cgggcgcggc atcggtgacc ttgagccggg gacgtgccct
    11221 gtaaccttgg gccatggccc ttggtcgacc ctccgtcctg cccgatcgtg tccccaccgt
    11281 ccgagacctg ctcgccgccg gtggccggtc gttctccttc gagttcttcc cgccgaagac
    11341 cgacgaggga gcgcggcagc tctggaaggc gatcagggag ctggagtcgt tgcggccgac
    11401 gttcgtgtcg gtgacctacg gcgcgggcgg ctccacgcgc gaccgcacgg tcggcatcgt
    11461 cgagcgcatc gcccacgaca cgacgctgac gcccgtggcg cacttcacgg cggtcaacca
    11521 ctcgatccgc gagctgcgcc acctcgtggg gcggttcgcc gacgccgggg tgcgcaacat
    11581 cctggccgtg cggggcgacc cgccgggcga tcccatggcc gagtgggtgc agcaccccga
    11641 cggggtgctg tactccgagg agctggtgcg gctgatcagg caggcgggcg acttctgcgt
    11701 cggcgtggcg gccttcccct acaagcatcc gcgctcgccg tccatcgacg ccgacaccga
    11761 atacttcgtc cagaagtgcc gggcgggggc cgactacgcg atcacacaga tgttcttccg
    11821 cgcggaggac tacctgcggc tgcgcgaccg ggtcgcggcc aggggctgcg acacgccgat
    11881 catcccgtgc atcatgccgg tgacgcagat gagcacgatc gcgcgctcgg agcagctgtc
    11941 gggggcgccc ttcccgccgg aggtggcggc ccgcttcgag gaggtggcgg acgacccgga
    12001 ggcggtgcgc cgcctcggca tcgagcacgg ggccgagctg tgccgccggc tgctcgacga
    12061 gggcgcgccg gggatccact tcatcacgtt caaccgctcc agcgcgtccc gtgaggtgtt
    12121 ccagcggctg aacgtcccat catctgttac ggcagggccg gctgggcgcc acccgctgcc
    12181 cgtggccggg ggcctccagg gggacgctcg ctgacccgca cgtggccggc cgccgcaacg
    12241 ccgccccctt ggccctcccg gtggttcaca agcattgccc ggaggcccac gccgcacgtg
    12301 agcgtccgca cgcggaggcg gccggaaaac ccctgcgccc gcgcctgacc tgccgtcatg
    12361 gcggtgccca tgtcggcgcg gacaccgcca tgacggaccc ggggcagctg tctggcccgg
    12421 ctcccgttcg atccgatgcg ttctgttccg gatcgcgttc ggggcgatca tcgccggcgt
    12481 gcctgacccg ccgagtggac ttctcaggga gagatttggt ggctgcttag ccctcagcat
    12541 tcctttcgcc agacttgtca tgatgcgtcg tatttagcct ggtcgttggg gggtgagggg
    12601 ttgacaaatg tatggcgtcg atggtcgata cgaaggcgct tgaccatgat cacggcagtg
    12661 gtgatgacca tcctgtgcct gagcatcagc gggctgatcc tgatgagggt ccacgacgag
    12721 cgcaccatgg agcgcaatca cctcaatcac gacgcggcca tgcgcgcggc cgccctcctc
    12781 gcccgtggcg accttcctcc ggtccacgcc gacccctcgg tgaccgccct ccaggtcatc
    12841 gatcccaccg gccggatcgt ctccacgagc cccagcatgg agggccggcc gcccctcgcc
    12901 tccttcgccc ctccacctgg ccgcctgggc gccgagcgca ccctgtgccg ggtgcccggc
    12961 tccggcgacg cgtgcttgct cgtttccgtc cagcgcgccc ccagaagcca cggtgactgg
    13021 atgatctacg ccgccgcccc ggcctacccc tggtacgtca gcggccgcct tctcgcaccc
    13081 ctgctcctgg gctgcgcgtt gatcgtcgcc ttcacgaccc tgggcgcgcg ccgcatcgtc
    13141 atcacctcgc tcagacccgt cgaggccatc cgggcgaaac tctccaaaat caccacaacc
    13201 gaactcgggc atcgggtgcc cgtccctcag cctcgggacg agatccatga cctggccggc
    13261 accgtgaaca ccactctcga catgctggac gccgccctga cccgggagcg gcggttcacc
    13321 gccgacgcct cgcatgacct gcgcagcccc gtcaccgcca tgcggaccca ggtcgaagag
    13381 gcgctgttgc acccggacga gaccgactgg cccgccgtcg cgcgagccct gctcgccagc
    13441 ctcgaacggc tgcacgccat cgtcgccgac ctgatggagc tccgccgact ggacgcggac
    13501 gcgggcgccc cgatgatgcc cgtcgacctg aatgaactga tcgtccgcga actcgcgcgc
    13561 cggccccagg gcaagacgat cgtctccgac tgccggcccg ctctcgtgcg gggcgaccgc
    13621 gtacagctcc tccggttgct caccaatctc ctggacaacg ccgaacgcca tgccacctcc
    13681 accgttcacg tcaccctgca ctgtgagcag ggcgaggtcg cgctggtggt gcacgacgac
    13741 ggctccggga tcccggtcca ccagcgtgag gtggtgttcc agcgcttcgc ccggctcgac
    13801 gccgcgagga acaaggacgc cggaggttcc gggctcggcc tgccgatagc ccgggagatc
    13861 gcccggcatc acggcggcac gctcaccatc gaggactcca gccgaggcgc gcgtttcgtc
    13921 gcgcgcatcc ccctgtatcg gccgccgcac cggccgggca cgatccgggg ccatctcgat
    13981 cccgcgtgac gggatgggtg cgcccgccga gttgatcggc gtctccggtc cgatggctca
    14041 ggggacggcc tgatcgtcca ccaccccccg cggcggcctt tcgtgatggc cggccgcgcc
    14101 ccggctcgtc ctcggcgggt cggccggggt gacccgccac ccgcccgcag ggggaccggg
    14161 cgggtggacg ggcagggggc agtagacgct gggtaaagga gcggatacct tacgtaatga
    14221 atggtgcccg aagccatccc caggcaaacc catccgtcac cggggccccc gaaggtcgcc
    14281 ctcaggtcaa gggcaggggg cggcccacga tggcgtagtc ctcgtagccg cccgggaaga
    14341 cgaacctcgt gaggaggtcc gtgaagccca tgctggcgta gagatggcgg gcggcggtgg
    14401 gctggtcgtg ggtcgacagg atggccgagc gctcggggcg gccggcgcag agcgtgcgga
    14461 tcatcgcgcg gccgatgccc tggctctggt ggtcggggtg cacgtggatc tcggccagct
    14521 cgaagacgta ccccatccag gcgttcgcgg cctcctcgcc gagccggtcg gtcacggctc
    14581 ggagcaccac gtcgtgccac cactgccccg gcgcgccgcg gaagccgtac gcgaagccga
    14641 cggtcacggg gctggaaagg gacgaatcac gcaattccgc aaaataacac tggaaatgcg
    14701 gataagtcgc gtgatttcgc atgatggtct tgcggccgtt gatctggtcc gcgggcggct
    14761 tcatggcagc cgtgtaaatg tcgatcaccg tctccagccg ttcggcgaac tcggccggac
    14821 ccgcaccgcg aaactcgatc acccgacgca cactactcga cgtccacggc cgcacccccg
    14881 gtgatccgga caagctcgtc gaacgtcgtc gggaacaccg tcagcggatg ccccccggcc
    14941 gcccacacca cctcgtgctt gctcagccag ttgtccacca gggtccgcac gggcgccggg
    15001 tgcccgacgg gggccacgcc gccgatcggc tggcccgtgg ccgcccggac gaactccggc
    15061 gtcgcacggc gtaccttccc cacgcccacc gtgcgggcga tcagctccac gtccacgcgg
    15121 tgggccccgc tcgtcagcac gagcagcggc gcgccgtccg cgtcgaatat caggctgttg
    15181 gcgatggccc cgacctcgca cccgagctgg gccgcggcgg tggcggcggt gggcgccttc
    15241 tcgggcagga cgacgatctc gccgcccgcc ccgagctcgc gcagagcgga ttgtacgacg
    15301 acggcattcg acggcaactt ctcaggcatg gacacactct aaacaggttg accgcgtcat
    15361 taccgattca tggtgagtgg tgtagggtcc tctgatctat tcaataatgg tatgagaggt
    15421 gatacgcgtg ggggctcgac gggtgcccgg gatggctgct ctcctgacgg ccggcgccgt
    15481 cgcactctcg ggctgcggca cgcaggcgcc gcaacgactc acgacggccg caccggccgc
    15541 cgccaccgcg caggccgcac cggccgcgac ggcggcgtcc ccgtccgtca cccccggcgc
    15601 ggcgggcgcg cggtcaggcc ccgccgccac ggtcaccgcc ccgcgtaaga cgctcaagct
    15661 cggcgccaag ggcgaacccg tcgaatggct gcagaagcgc ctgatccagc tcggctaccg
    15721 ccccggcagg gtcgacggcc gctacggcaa cacgacgctg gccgccgtgt gggcgttcca
    15781 gaaagtgaac gacatcaggc cgaccagcac catcgccaag cgcacgtggg aggccctgga
    15841 gaccccgaag gcgcccaggg tcctcgtcaa gaacggcagg ccgacccgcg ccgaggtcaa
    15901 cctcaccaag cagatcatgg tcatgtacgt ggacggcgag gcgaagctga tcacccacat
    15961 ctcgtcgggc agcggcatcc cttattgcga gacggccagc tggcagggca agcggcagcg
    16021 gttctgcggc tcggccacca cgccgacggg caactaccgg accacgtggc gggtccacgg
    16081 ctggcaccgc tcctacctgg ggcagctcta caacccgatc ttcttcaacg gcggcatcgc
    16141 cctgcacggg gcgctgtcgg tgccgctgta tccggcctcg cacggatgcg tgcgcatgcc
    16201 gatgaacgtg gccgaggtcc tgccggggat gctcggcaag ggcgtgccgg tgcacgtccg
    16261 gggcaagttc cggcgcgcct gagccgctcc gccccggcct ccggggcggc gtaacgtccg
    16321 cataaccgca tcgggtgacg gcccggttat gggctgcctg ctggactccc tcctgacgtt
    16381 ctcgggggga gtccatgacg acggtgctca ctgtgtccgc gcccgcgccg gcgcggcggt
    16441 cccggctgcg gtggctgctc gcggccgggt gggtcgcgca cgtggtgctg cggctgtggt
    16501 tgtaccggta ccacgcgggt cctgtggcca atccggacga gaccggctac ctgctcgccg
    16561 cccgctggct ggcgggcggt cccggcgccg acctgtcggg ctcgaccttc taccagggcg
    16621 ggtacccgct gctgctcgtc ccgatcttcc ggctcacctc cgaccccgtc ctggcgtacc
    16681 ggctggtggt cgtggcgggg tccatggcgg cggcgggggc gtacccgctg gcgtacctgc
    16741 tgctgcggcg gttcggcgtg ggccggaggg tcgcgctggt cacggcgttc gtggcggggc
    16801 tgtcgccggc gctgctggtg ttcccggggc tcgcgctggc cgacgcgatc ctgcccgcgc
    16861 tcgtgctcgc ctggctgctc gcggtgcacg atctggtcgc gtacggctcc gccagggccg
    16921 gggcggcggc gggcgcgctg tcggcgttcg cgatggcggc gcacctgcgc ggcacggtgc
    16981 tcctggcggt ctgcgtgctc gtcgcggtgg ccgcgatgtc gtcacggcgg gaaccacggg
    17041 tgcggctgcg ccgggccgtg ccgtcatcgc ggccctggga ggcgctgtac cgccgcgtgc
    17101 gggcgatggc gtaccggcgg agggcggccc tcgtggcgac ggcggtggcc ggcgtggtgg
    17161 cggcggccgg gcaggcgctc aacgggccgc tggcggcggc gctgtacccc ggcgggaccc
    17221 gcgatctgtc cgggctgctc ctgaccaggc tcacgagcgc cgacgggcag gcgtgggcgc
    17281 tgtcgggcgc ggccgggcag ctctggtacc tcgtcgccgg cacctggggg ctggccggcg
    17341 tggggctggc gggcgcggcg gccctcctcg tacggcgatc cgcgccgtac ccccaccgcg
    17401 tcctggccgc cgcgctgctg ctcacgaccc tcggcatcgc ctacgcctcc tcggccgccc
    17461 tgccggacga gcaccgcgtc ggcaactacg tctacggccg ctacctggcc tgcgtcgcgg
    17521 tggcctggac cctggccggg ctggtggcgc tcctgaaggg cggccgccgc gccgtcgtgc
    17581 ggctcgctct cgccgccgcc gcgctgacgg cggcgaccgg cggggtggcg gcctggtacg
    17641 cgggggaccg gctgcggcgc taccacttca tcgccttcga cttccccgaa gtgatcttcc
    17701 tcaccggcga cggcgactcg ctggacctcc tctcggcctc cgtgcccgcg ctgatcatgc
    17761 tgtcctgcct ggtgggcgtg gctttcgtca ccaccggccg cggccggatc ctggtggtgg
    17821 gcgtgctggc gctgatcgac atggcgttcg cggccgggca ggcgcccgcg cgccccccgg
    17881 gggcggactg gctgcccgac ccgccccttg ggcgggtggc ggtggatcgc cgggtgaggt
    17941 ggaacctgtg ggtgccgctc gcgtaccggg tgtcgtggac cgagatcgag ctgtacgacg
    18001 ggggcccgcc ggacggcgcc tgcaccgccg tcgtcccgta cggcaccgcg ccgccgcccg
    18061 gctgggccgc gaccgggcgc ggcggcgccg ggacgggctg gacgagctgg tcgaacgagc
    18121 ggtgctagcc ggactctgcg gcgagggcgc gcctgccctc gccggtggcc gccgacaggc
    18181 cgatcgcctg caacagcgcg gccaccacga gaaggacgac cgtgcccgcc tgccagccgg
    18241 ggagccccgc ggcgaagccg ggcgagtcgt agagcgccgc cagccccgcc accgggttga
    18301 gcagcgcgac gaacacggcg agggcgtacg gcacgatcag gacgcccgac agcacgaaca
    18361 ggaacgtgcg cctcctgctc cccctccgca acagcaggcc gatgacggcg taggccaccg
    18421 cgagagcgcc cgccagcagt gcggtcatca agaccacccg ccagacgtcg gtgccgagcg
    18481 cggtcatctc gtcggggccg ggcagggcgc cctcccactc cgggctcgcg acctgcgccc
    18541 gcacggccgc cttgatggcc acgaggttgg cgcccgcgta cgtcgcggcc aggaccgggc
    18601 ccagcgccag caggtagagc gtgatcggcc gcctgctccc cgtcattcgg cttcccctcc
    18661 gctcagaacg gaccccggac gcgcggacca gcctaaccga gtgagcacag gccggacagc
    18721 gtcagctcgg ccgcgcgccg cgccgtctcc gccatgtcct ccacggagga gccggagtcc
    18781 atgttcgcga tgatcgcgag cttcaccgcc ccgaacaccg ctcccacggc ggcggccgcc
    18841 tccaccgggc cgagctcgtc ggggtagctc tcgtgcagcg cccgcgccag ccggacctgg
    18901 ctctcgatca gcatcatcag cgcccgcgcc tgcagggtgg gctccttcag cacgaggcgc
    18961 agccgcagcc ccgcgtcctc gaacgagaac tcctcgtacg tggtcagcca gcacatgctg
    19021 tcgcgcacca gcctgcgcag cacgtcggcc ggcgactccc cgggcgcccg gccggccagg
    19081 gtggcgaccg cgaggtccat ccggcgggcg gagtcgtaga agacgacgtc ctccttgctc
    19141 gcgaagtagc tgaagaacgt gcgcgtcgac acctcggcct cggcggcgat ctcggcgagc
    19201 gtggtctcct cgtagccctt ctcgtcgaac aaccggaacg cggcctcgac cagcgcccgg
    19261 cgcgtgcgct gcttcttgcg ctcccgcagt ccggcgccac cgctctgcac catgacggca
    19321 ctatacgtca gccgtggatc tttttcatgc attgaagttt tgcaaccgct gaggttttct
    19381 gggggtcaag ctcggaaagg agcagcggca tgtccgacgt cacgtttccc atcgcccgcc
    19441 agcgcccgct cgacccgccc gacgaggcca ccgagctgcg gcaacgggcg gccatgcatc
    19501 gcatgacgta cgccgacgga caccggggct ggctggtgac cggctattcg gcggcccgcg
    19561 ccatcctggc gcatccgcac ttcagcaacc gggcggaggt ctcgcacccg cccattcccg
    19621 gcaggttcga acggctgagg accaagaccc cgccggggtt cttcatccgt gccgacgcgc
    19681 ccgagcacac ccgctaccgc aaactgctca ccgggcagtt caccgtgcgc aggatgaagg
    19741 cgctggagcc gaggatcgag gagatcacca acgcctgcct cgacgacatg gccgccgcgg
    19801 gcggccccgt ggacctcgtg caggcgttcg cgctgccgat cccgtcgctg gtgatctgcg
    19861 agctgctcgg ggtcccgtac gccgaccgcg aacagttcca ggaggacacc aagctgctgg
    19921 tcaacctgga gaccaaggcg gaggagtcga tcgccgcgct cggccggagc atggcgtacc
    19981 tggcggggct gatcaagcgc aagcgcgagg agccggccga cgacctgctc agcggcctca
    20041 tcgagggcgg tgagctggac gacgaggagc tcaccggggt cgggttcctg ctgctggtgg
    20101 ccgggcacga gacgaccgcc aacatgctgg ggctcggcac gtacgcgctg ctcaccaacc
    20161 ccgaccagct cgccgccatg cgcgacgacc cgtcggtggt ggacaacggc gtcgaggagc
    20221 tgctgcgtta cctcacgatc gtccacctcg gtccggtacg caccgcgctg gaggacgtcg
    20281 agatcgaggg caccacgatc agggcgggcg agtccgccac catccacctg ccgtccgtca
    20341 accgcgacgc cgagcgcttc ccgggcggcg accggctcga cctggccagg cccgcgaccg
    20401 gccacatgag cttcggccac ggcatccacc agtgcctcgg tcagcagctc gcgcgtacgg
    20461 agatgcgcat cgcctacccc gcactgctgc gccgcttccc gggtctacgc ttggccgtaa
    20521 cacccgagga ggtgccgatg cgctcggaca tgagcatcta tggagtgcac cgcctcccag
    20581 tcacttggta ggtcaccatg gaaatcaagg cagatacgac ggtgtgcatc ggcgcgggca
    20641 tgtgcgctct tacggccccg caggtgttcg accagagcga ggacgagggc acggtggtgc
    20701 tcctgcagaa ggtgccgccg caggagctgg aggaggccgc ccgccgggcc gtgaccctgt
    20761 gcccgtcggg cgcgatctcc atcgtctgac gctcgcctga ccaccgtctg aaacggcggg
    20821 gccgtcgccg cgttcgcggt ggcggcccct ttttgatcac gactcgtcga acctgtgttc
    20881 gtggattcgg ttgacacaga gggtgatcga aattatgttc gacctagtga cggctgaggc
    20941 tcgcggctca ccgtcacctg gacctggtcg cgggccgttc gcttccccaa agcgattccc
    21001 gcggccagga tccatgggcg aagggcgcgt cctcgtcgtc ggcggagacg agtgggcgtg
    21061 tcctggcc
//
