LOCUS       NZ_CP045606            20891 bp    DNA     circular CON 16-FEB-2024
DEFINITION  Bacillus cereus strain SB1 chromosome, complete genome.
ACCESSION   NZ_CP045606
VERSION     NZ_CP045606.2
KEYWORDS    RefSeq.
SOURCE      Bacillus cereus
  ORGANISM  Bacillus cereus
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 5461537)
  AUTHORS   Batinovic,S. and Petrovski,S.
  TITLE     Bacillus cereus SB1 complete genome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5461537)
  AUTHORS   Batinovic,S. and Petrovski,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2019) Department of Physiology, Anatomy &
            Microbiology, La Trobe University, Kingsbury Drive, Bundoora,
            Victoria 3086, Australia
  REMARK    Sequence update by submitter
REFERENCE   3  (bases 1 to 5461537)
  AUTHORS   Batinovic,S. and Petrovski,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2019) Department of Physiology, Anatomy &
            Microbiology, La Trobe University, Kingsbury Drive, Bundoora,
            Victoria 3086, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: NOV-2019
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 46x
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/16/2024 03:34:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,375
            CDSs (total)                      :: 6,221
            Genes (coding)                    :: 5,991
            CDSs (with protein)               :: 5,991
            Genes (RNA)                       :: 154
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 107
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 230
            CDSs (without protein)            :: 230
            Pseudo Genes (ambiguous residues) :: 0 of 230
            Pseudo Genes (frameshifted)       :: 89 of 230
            Pseudo Genes (incomplete)         :: 140 of 230
            Pseudo Genes (internal stop)      :: 70 of 230
            Pseudo Genes (multiple problems)  :: 57 of 230
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:27:55
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4213087
            Orig. end                         :: 4233978
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP045606.2.
            On Dec 19, 2019 this sequence version replaced NZ_CP045606.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Steve Petrovski, La Trobe
            University, Bundoora, 3086, VIC, Australia.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20891
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="11"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20891
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20891
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10891](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10891)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    389..405
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.73"
                     /tool="antismash"
     gene            668..814
                     /locus_tag="GE376_RS21155"
                     /old_locus_tag="GE376_21630"
     CDS             668..814
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247674.1"
                     /locus_tag="GE376_RS21155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_21630"
                     /product="YycC family protein"
                     /protein_id="WP_001247671.1"
                     /transl_table=11
                     /translation="MRPLQISPDTAVRLSKALGVPLEQLMHMPQHILIQKLVELEKQNK
                     DEE"
     gene            complement(1054..1617)
                     /locus_tag="GE376_RS21160"
                     /old_locus_tag="GE376_21635"
     CDS             complement(1054..1617)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012261692.1"
                     /locus_tag="GE376_RS21160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_21635"
                     /product="PRK06770 family protein"
                     /protein_id="WP_000790987.1"
                     /transl_table=11
                     /translation="MKNKILTWLGIVAAMGVLAVAVTFGMLELADNPADKEVSAQIDKK
                     EDQTIVGREVDGVFVDVYVTENSTESEVIIAMHHMTHQKVVAERKSGSIPMVQNNAKKL
                     KEIINKSSFAKKNELLAIADRWVKKDFSKIVEDHNYFSDAQEDSVCKATRAMDALEEQH
                     YILTTFGEEKAKELYESGDAPHVQ"
     gene            complement(1869..2663)
                     /gene="spo0A"
                     /locus_tag="GE376_RS21165"
                     /old_locus_tag="GE376_21640"
     CDS             complement(1869..2663)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /GO_process="GO:0042173 - regulation of sporulation
                     resulting in formation of a cellular spore [Evidence IEA]"
                     /codon_start=1
                     /gene="spo0A"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390302.1"
                     /locus_tag="GE376_RS21165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_21640"
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="WP_011110369.1"
                     /transl_table=11
                     /translation="MEKIKVCLVDDNKELVSMLESYVAAQDDMEVIGTAYNGQECLNLL
                     TDKQPDVLVLDIIMPHLDGLAVLEKMRHIERLKQPSVIMLTAFGQEDVTKKAVDLGASY
                     FILKPFDMENLTSHIRQVSGKANAMIKRPLPSFRSATTVDGKPKNLDASITSIIHEIGV
                     PAHIKGYMYLREAISMVYNDIELLGSITKVLYPDIAKKYNTTASRVERAIRHAIEVAWS
                     RGNIDSISSLFGYTVSMSKAKPTNSEFIAMVADKLRLEHKAS"
     misc_feature    complement(2733..2747)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.49"
                     /tool="antismash"
     misc_feature    2869..2882
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.66"
                     /tool="antismash"
     gene            complement(2951..4249)
                     /gene="spoIVB"
                     /locus_tag="GE376_RS21170"
                     /old_locus_tag="GE376_21650"
     CDS             complement(2951..4249)
                     /EC_number="3.4.21.116"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIVB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002164433.1"
                     /locus_tag="GE376_RS21170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_21650"
                     /product="SpoIVB peptidase"
                     /protein_id="WP_063548618.1"
                     /transl_table=11
                     /translation="MNKLKLEKFRKIIGLCLLVSLVFIGCFKPLRTFISSPKQLVVFEG
                     QQSEISSLPVFKASSTNRHVFTVSSNEQKQGLMVNSHQNGEADMVFQLAGFPVKKVNVK
                     VLKDFKVIPGGQSIGVKLNTKGVLVVGHHLIQTEKGKISPGETAGVQIGDMITEINGKT
                     IERMSDVAPFIHNSGETGEPLNLVLLRDGKYIRTKLTPQKDNGEASYRIGLYIRDSAAG
                     IGTMTFVHPDSMKYGALGHVISDNDTKKPIQVEDGQIMRSTVTSIERGSHGNPGEKLAR
                     FSPDREVIGNITINSPYGIFGKLNTNMKNGIMDKAMPIALSHQVKEGPAKILTVIDQDK
                     VEAFDIEVVSTVQQKFPATKGMVIKVTDKRLLAKTGGIVQGMSGSPIVQNGKVIGAVTH
                     VFVNDPTSGYGVHIEWMLHQAGINIYDQEKKAS"
     gene            complement(4368..6107)
                     /gene="recN"
                     /locus_tag="GE376_RS21175"
                     /old_locus_tag="GE376_21655"
     CDS             complement(4368..6107)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002122413.1"
                     /locus_tag="GE376_RS21175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_21655"
                     /product="DNA repair protein RecN"
                     /protein_id="WP_000947734.1"
                     /transl_table=11
                     /translation="MLSELSIRNFAIIEALNISFQKGLTVLSGETGAGKSIIIDAISLL
                     VGGRGSAEFVRYGTEKAEIEGLFYVEDDKHPCIEKAEELDIEIEDGMIILKRDIAANGK
                     SVCRVNGKLVTLSILKEIGKTLVDIHGQHETQDLMNEERHLFMLDHFDGDRIVKQLDIY
                     QNVYADYEKLKKQLKSLSENEQQMAHRLDLIQFQHEEIRKADLKMDEENELTEERLQIS
                     NFEKIYKALGDAYRSLSADGQGLDNVRSAMGQMESITHLDEMYQENHDSIANSYYLLEE
                     VAYQLREKLDMMEYDPNRLDEIETRLNEIRMLKRKYGNTVEEILAYADKIEQEIFTIEN
                     KDVHIETTKKQLKELESVILKEATLLSNMRHELAEHLTNAIHQELKELYMEKTKFEVRI
                     MKREGNAEEPLVEGAPVRLTADGYDHVEFYISTNPGEPLKPLSKVASGGELSRIILALK
                     SIFSKHQGVASVIFDEVDTGVSGRVAQAIAEKIYRVSVNSQVLCITHLPQVASMADSHL
                     FIRKQVANDRTITSVTVLTMEDKVTEIARMISGVEITDLTTEHAKELLTQAHHFKQTAE
                     AIQ"
     misc_feature    6225..6238
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 21.32"
                     /tool="antismash"
     gene            complement(6372..6821)
                     /gene="argR"
                     /gene_synonym="ahrC"
                     /locus_tag="GE376_RS21180"
                     /old_locus_tag="GE376_21660"
     CDS             complement(6372..6821)
                     /codon_start=1
                     /gene="argR"
                     /gene_synonym="ahrC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017150893.1"
                     /locus_tag="GE376_RS21180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_21660"
                     /product="arginine repressor ArgR"
                     /protein_id="WP_001032580.1"
                     /transl_table=11
                     /translation="MNKGQRHIKIREIIANKEIETQDELVDILRNEGFNVTQATVSRDI
                     KELHLVKVPLHDGRYKYSLPADQRFNPLQKLKRNLVDSFVKLDTAGHMLVLKTLPGNAH
                     SLGALIDHLEWDEIIGTICGDDTCLIICRTPDDTGVVSDRFLNML"
     gene            complement(6964..7803)
                     /locus_tag="GE376_RS21185"
                     /old_locus_tag="GE376_21665"
     CDS             complement(6964..7803)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016125811.1"
                     /locus_tag="GE376_RS21185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_21665"
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_000111872.1"
                     /transl_table=11
                     /translation="MSVKKERVDVLLVERGLIETREKAKRAIMAGLVYANEMRLDKPGE
                     KISQDTEITVKGQVMPYVSRGGYKLEKALETFHLDLQDKVMIDIGSSTGGFTDCALQNG
                     AKLSYALDVGYNQLAWKLRQDERVVVMERTNFRYVTPADLERGLPQFASIDVSFISLKL
                     ILPVLKTMLMPNGDVAALIKPQFEAGREQVGKKGIVRDRKVHEAVVEMIVDFALKEGYD
                     VEGLTFSPITGGDGNIEFLIHLKWHGERENGENHSPISIEQVVTEAHDVLKQKGKGE"
     gene            complement(7807..9699)
                     /gene="dxs"
                     /locus_tag="GE376_RS21190"
                     /old_locus_tag="GE376_21670"
     CDS             complement(7807..9699)
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366453.1"
                     /locus_tag="GE376_RS21190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_21670"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_000366452.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 7.9e-120,
                     bitscore: 397.5, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.6e-06, bitscore:
                     26.3, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLTQIQNPSFLKDMSISELEGLSEDIRKFLIEELSQTGGHIAPN
                     LGVVELTIALHKLFDSPQDKFLWDVGHQSYVHKILTGRAKEFGTLRQYQGLCGFPKRCE
                     SEHDVWETGHSSTSLSAAMGMALARDLKKTKEYVIPIIGDGALTGGMALEALNHIGHEK
                     TDMIVILNDNEMSIAPNVGALHNVLGRLRTAGKYHWVKDELEYILKKIPAVGGKVAATA
                     EKIKDSLKYLLVSGVFFEELGFTYLGPVDGHDYEKLFETLQYAKKTKGPVLVHVITKKG
                     KGYKPAESDVIGTWHGTGPYKIESGDFVKPKEVAPAWSAVVSETVLKLARADERIVAIT
                     PAMPVGSKLEKFQKEFPDRMIDVGIAEQHATTMAAGMATQGMKPFLAIYSTFLQRAYDQ
                     VVHDICRQNLNVFIGIDRSGLVGADGETHQGVFDISFLRHLPNMVLMMPKDENEGQHLV
                     YTAMQYEDGPIALRYARGNGLGVHMDEELKAIPIGTWETLKEGTQAAILTFGTTIPMAM
                     EAAERLEKAGVSVKVVNARFIKPMDEAYLHDLLGKNIPILTIEEACLIGGFGTGVVEFA
                     SENGYHSALVERMGIPDRFIEHGSVTKLLEEIGLTTDAVVDRIHTMIPSKQKRA"
     gene            complement(10001..10891)
                     /gene="ispA"
                     /locus_tag="GE376_RS21195"
                     /old_locus_tag="GE376_21675"
     CDS             complement(10001..10891)
                     /EC_number="2.5.1.10"
                     /codon_start=1
                     /gene="ispA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016080323.1"
                     /locus_tag="GE376_RS21195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_21675"
                     /product="(2E,6E)-farnesyl diphosphate synthase"
                     /protein_id="WP_000150374.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.4e-61, bitscore:
                     204.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIAFDTFLKESKTFVEEKLVSYANELQCPNVLREAMAYSLEAGG
                     KRLRPLLLFATLQAFGKERNLGVGAACALEMIHTYSLVHDDLPCMDDDDLRRGKPTNHK
                     VFGEAMAVLAGDGLLTYAFQVIMAYEQKEISAEKKVRLVLELAKAAGPEGMVGGQVADM
                     EAEGKRLTIDELEYIHKHKTGKLLEFAVLAGAILSDATEEQEEKLLTFAKYIGLAFQIR
                     DDILDVEGTEEEIGKPIGSDLSNEKSTYTTLFTVDRAKDILEETIAEAKGAISSLQLQD
                     EYLLSICDLIAKRNN"
     gene            complement(10891..11121)
                     /gene="xseB"
                     /locus_tag="GE376_RS21200"
                     /old_locus_tag="GE376_21680"
     CDS             complement(10891..11121)
                     /EC_number="3.1.11.6"
                     /codon_start=1
                     /gene="xseB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428424.1"
                     /locus_tag="GE376_RS21200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_21680"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_000428423.1"
                     /transl_table=11
                     /translation="MENKLSFEEAISQLEHLVSKLEQGDVPLEEAISYFKEGMELSKLC
                     DEKLKNVQEQMAVILGEDGELEPFTALGDEA"
     gene            complement(11111..12469)
                     /gene="xseA"
                     /locus_tag="GE376_RS21205"
                     /old_locus_tag="GE376_21685"
     CDS             complement(11111..12469)
                     /EC_number="3.1.11.6"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415245.1"
                     /locus_tag="GE376_RS21205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_21685"
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_000415253.1"
                     /transl_table=11
                     /translation="MEKQYLTVTALTRYIKTKIEYDPHLQSVWLKGEISNFKNHSRGHM
                     YFTLKDENARIAAVMFAGHNRNIKFKPENGMKVLVKGKISVYEASGSYQIYIQDMQPDG
                     VGNLHLAYEQLKVRLEEEGLFSQVYKKAIPPYAKTIGVITSPTGAAIRDIITTIKRRYP
                     IGNVIVFPVLVQGESAAPSIVQAIRTANEMREIDVLIVGRGGGSIEELWAFNEEMVARA
                     IFKSEIPIISAVGHETDFTIADFVADLRAPTPTAAAELAAPNIIELQEKVLQRTLRLQR
                     AMKELVHKKEEKLQVLQKSYAFRYPRQVYEQKEEQLDRALEQLVLAKERYIDKKVNQLK
                     QLSFYLEKHHPSQKIIQTKVAVETLQKQLQREMQTLLQTKEFAFVRAAQKLEALSPLKV
                     MMRGYGLVYDEEKQVLKSVKDVSLGDAVSVQLQDGILDCSVSGIEERELNNGK"
     gene            complement(12496..13356)
                     /gene="folD"
                     /locus_tag="GE376_RS21210"
                     /old_locus_tag="GE376_21690"
     CDS             complement(12496..13356)
                     /EC_number="1.5.1.5"
                     /EC_number="3.5.4.9"
                     /GO_function="GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /gene="folD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226722.1"
                     /locus_tag="GE376_RS21210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_21690"
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD"
                     /protein_id="WP_000226732.1"
                     /transl_table=11
                     /translation="MVAVIIKGNEVAEKKRAQLTEEVVKLKEQGIVPGLAVILVGEDPA
                     SRSYVKGKEKGCEQVGIYSELIELPETITEERLLAEIDRLNGDDRINGILVQLPLPKHI
                     EEKAIIERISPEKDVDGFHPISVGRMMTGQDTFLPCTPHGIVELVKETNLDISGKHVVV
                     IGRSNIVGKPVGQLFLNENATVTYCHSKTQNMKELSKLADILIVAVGRPKMITADYIKE
                     GAVVIDVGVNRLETGKLCGDVDFDNVLDVAGYITPVPKGVGPMTITMLLHNTVESAKRA
                     GVVCK"
     gene            complement(13380..13772)
                     /gene="nusB"
                     /locus_tag="GE376_RS21215"
                     /old_locus_tag="GE376_21695"
     CDS             complement(13380..13772)
                     /codon_start=1
                     /gene="nusB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018780784.1"
                     /locus_tag="GE376_RS21215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_21695"
                     /product="N utilization substance protein NusB"
                     /protein_id="WP_000830247.1"
                     /transl_table=11
                     /translation="MKRRTARERAMQALYQMDITGELEPKVAVENTLDEGEETNEFLES
                     LVVGFVENKEAIDEAIRQNLKKWKLERISIVDRSILRVAVYEMKYMEEIPHNVTINEAI
                     EIAKTFGDEESRRFINGVLSNIKDTL"
     misc_feature    complement(13811..13827)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 25.4"
                     /tool="antismash"
     gene            complement(14119..14511)
                     /locus_tag="GE376_RS21220"
                     /old_locus_tag="GE376_21700"
     CDS             complement(14119..14511)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012095336.1"
                     /locus_tag="GE376_RS21220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_21700"
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="WP_000807630.1"
                     /transl_table=11
                     /translation="MAEHMLDMGQDTTLGKVEIAPEVIEVIAGIAAAEVEGVAAMRGNF
                     ATDVVEKLGKKNHGKGVKVELANEDIIVDLYVVMYFGVAIPVVAQKIQDNIRQALFTMT
                     GLEPKEVNVHIVGVTFETQKTEIEPV"
     misc_feature    14482..14495
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 21.28"
                     /tool="antismash"
     gene            complement(14534..15886)
                     /gene="accC"
                     /locus_tag="GE376_RS21225"
                     /old_locus_tag="GE376_21705"
     CDS             complement(14534..15886)
                     /EC_number="6.3.4.14"
                     /GO_component="GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA]"
                     /GO_function="GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA]"
                     /GO_function="GO:0004075 - biotin carboxylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="accC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003200233.1"
                     /locus_tag="GE376_RS21225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_21705"
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_000592870.1"
                     /sec_met_domain="ATP-grasp (E-value: 4.9e-09, bitscore:
                     34.3, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 6.9e-09,
                     bitscore: 33.8, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKKVLIANRGEIAVRIIRACKEMDIETVAIYSEADKESLHVQIA
                     DEAYCVGPTISKESYLNLTNIISVAKLTGCDAIHPGYGFLAENADFAELCRECNLIFIG
                     PSPEAISKMGTKDVARDTMKEAGVPIVPGSQGIIKNTEEAIELANQIGYPVIIKATAGG
                     GGKGIRVARHEEELIKGIQITQQEASTAFGNPGVYLEKYVEDFRHVEIQIMADTHGNAI
                     HLGERDCTIQRRLQKLLEESPSPALDEDIRKQMGEAAVKAAVAVDYTGAGTVEFIYEYK
                     TKTFYFMEMNTRIQVEHPVTEMVTGMDLIKEQILVASGEKLSLQQEEVQFNGWAIECRI
                     NAENPAKKFMPSPGKVEMYLPPGGFGIRVDSAVYPGYSIPPFYDSMVAKLIVHGKTREE
                     AIAKMKRALSEFVIEGVHTTIPFHLQLLDHPDFVKGEFNTKFLEEHELVTQ"
     gene            complement(15903..16391)
                     /gene="accB"
                     /locus_tag="GE376_RS21230"
                     /old_locus_tag="GE376_21710"
     CDS             complement(15903..16391)
                     /EC_number="6.4.1.2"
                     /GO_component="GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA]"
                     /GO_function="GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="accB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472875.1"
                     /locus_tag="GE376_RS21230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_21710"
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="WP_000472863.1"
                     /transl_table=11
                     /translation="MFKIQEVRELIKLIDSSNIDEFEYKKDGTTIKMKKRGNEVVAVQA
                     PAAKQAMQPVAPVEVETTVAAAQAEAPKQEEKKTVQDENLHKITSPMVGTFYSSSSPDT
                     PPYVSVGDRVSKDSIVCIVEAMKLFNEIDADVEGEIVEILVNNGQLVEYGQPLFLVKA"
     gene            16861..17055
                     /locus_tag="GE376_RS21235"
                     /old_locus_tag="GE376_21715"
     CDS             16861..17055
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638008.1"
                     /locus_tag="GE376_RS21235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_21715"
                     /product="hypothetical protein"
                     /protein_id="WP_002000935.1"
                     /transl_table=11
                     /translation="MIWLILFLPAVIVWACVLCIHVKSGKSNHQYHEPLIFYSQRVSPF
                     RVEHSKNNYKDEIEKSYRK"
     gene            complement(17169..17813)
                     /locus_tag="GE376_RS21240"
                     /old_locus_tag="GE376_21720"
     CDS             complement(17169..17813)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016077257.1"
                     /locus_tag="GE376_RS21240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_21720"
                     /product="SpoIIIAH-like family protein"
                     /protein_id="WP_000914710.1"
                     /transl_table=11
                     /translation="MLKKQTVWLLTMLSLVVVLSVYYVTTPDKMNTASPATGEKIGQEK
                     QGTDKAVTNEAPKETPKKENTSKETTNKETDKKENAKKETSKKEGNVSVQSSDENFTAL
                     RMQMEDQRSEQKAKLQEVMSSTKASATEKNKAKENFDAITTMETKQELLETVIKSQGGY
                     PDALVRADGTDIRVTVKAAKHSQKEANKIIQLVRSEGGSKDVGVKFDPPAK"
     gene            complement(17829..18491)
                     /gene="spoIIIAG"
                     /locus_tag="GE376_RS21245"
                     /old_locus_tag="GE376_21725"
     CDS             complement(17829..18491)
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002173413.1"
                     /locus_tag="GE376_RS21245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_21725"
                     /product="stage III sporulation protein AG"
                     /protein_id="WP_000368890.1"
                     /transl_table=11
                     /translation="MDNKDKNSKFSFFRNLLNGDQKESNEKGKKVTPKFLLVLLILGIL
                     LMFSSSLFSSKKEEVPVFKEQKTQNQEKDVPTFGQKSNDSMSNVEKYEKAYEQELKTAL
                     EEIAGVKDVTIKVNLDSSEEKILEKNTVKRSQTTGETDKTGGKREVEDESLDEKTVIIR
                     EGDKETPVVLRTEKPKVRGVLVVAKGVDNIQVKAMVKEAVIRLLDVPAHRVSVSPKN"
     gene            complement(18481..19113)
                     /gene="spoIIIAF"
                     /locus_tag="GE376_RS21250"
                     /old_locus_tag="GE376_21730"
     CDS             complement(18481..19113)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001161027.1"
                     /locus_tag="GE376_RS21250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_21730"
                     /product="stage III sporulation protein AF"
                     /protein_id="WP_001161037.1"
                     /transl_table=11
                     /translation="MQFVTEWIRNIIVFLLLATMLHLILPNSNLQKYVKFVVSLLLVVL
                     ILTPLFKLLQTDVNEVIANFNEEKYVAEGSVKNSIDSKKKEIQALTRAYSLEEMATKMK
                     KEVGKEFEKKYGMTVSEIQIVAAENTEEVKSAKDIQSVVVTLKEKERSKNDAIETVKPI
                     EINTKEPPKKVEETNVEMKDFFSSRWQLEGKQIQVQMEGRTGRVNGQ"
     gene            complement(19126..20298)
                     /gene="spoIIIAE"
                     /locus_tag="GE376_RS21255"
                     /old_locus_tag="GE376_21735"
     CDS             complement(19126..20298)
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946108.1"
                     /locus_tag="GE376_RS21255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_21735"
                     /product="stage III sporulation protein AE"
                     /protein_id="WP_000946113.1"
                     /transl_table=11
                     /translation="MLRRFGAKLLFACFLFFSLPVVVQASPVETNVVDQQLDKLGIEDV
                     KQFWDGLVTKYGGYLPESQKGSFMEFVKGEKEFSLKEWMIGLLKYLFHELAANGKLLGT
                     LIMLTIFSALLQSLQSAFSKSSVSKIADAVVYMVLIIFALNSFYVVMTYARETIQTMVD
                     FILALLPILLALIATGGGVVSVSFFHPVIIFLMNTSGLLMNYIVLPLLLLATILSIVST
                     MSDQYKVTKLSKLLQNVSVGIIGVFLTIFLGVLSVQGTATAVADGIAVKTAKFVTGNFI
                     PVVGRMFTEAADTVISASGLLKNTVGIIGLVILCLIVAFPAIQIFCIAFIYKFAAAVLQ
                     PVGGGAIIQCLDIIGRSIIYVFACLAIVSFMFFLSITIIIAAGNITLMMR"
     gene            complement(20309..20692)
                     /gene="spoIIIAD"
                     /locus_tag="GE376_RS21260"
                     /old_locus_tag="GE376_21740"
     CDS             complement(20309..20692)
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017150877.1"
                     /locus_tag="GE376_RS21260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_21740"
                     /product="stage III sporulation protein AD"
                     /protein_id="WP_077393170.1"
                     /transl_table=11
                     /translation="MQIVGLGLVATFLAAVLNQHKSSITSLFIVFVGSVMFLILIDQIH
                     SILQMIERVASEAKVSNVYVETLLKIIGIAYIAEFGAQITKDAGQGAIASKIELAGKIL
                     ILVMAIPILTVVIETILGFLPTG"
ORIGIN
        1 gggcgaacct ctacaccact ttccatcgtt agttcggcaa tagcatcttg aagataacga
       61 taattcggat gtactgctgt agctcccatt ttttttgcgt atgcccacgg actatgcaaa
      121 ccttcgcgat ataaaatagc tgtttgaata tcaggagcca tcatatggca ccgtttcata
      181 ctgtagtgat taaacgaaga aaatacaacg cgatcctcta aactaaattt ccgtacaagc
      241 gttataactt cttcctctaa acctctgtat ggaattttat tatttttaag ttcaatatta
      301 agtagcaaac tcgttcgttc aagccattct aatacctctt ctaaaagtgg tattttacaa
      361 aaccctactt tatcaccaaa tttataactt gcatctaact tgcataaatc ctcatataca
      421 taattccgaa ccgcaccttt tccatttgtt gtccggtcca ccgtttcatc atgaatgacg
      481 acaacttttc catctttcgt taattgaaca tcaagttcaa ttccatccgc tctaaaagac
      541 tcagccgctt caaatgaaat cattgtattt tctgggtacg ttccagccgc accacgatgt
      601 gcaaatataa gagtcatcct cactccccca atcttatgct atactatacg aaaaaggagg
      661 tacttctatg agaccattac aaatttctcc agatactgca gtccgcttat caaaagcact
      721 aggtgttcca cttgaacaac tcatgcatat gccgcagcac attttaattc aaaagctagt
      781 tgaattagaa aaacaaaata aagacgaaga gtaatacagt cctgttttgc agggcttttt
      841 attgccctcc attataccat ggatactttc cctactaaaa ttctttaata gatgtacttc
      901 ggtgcaattt agccgttcct tcatcattta ataatgaatc atatcttttc ttttttgtta
      961 caagtcataa agaaagcaga ctatttattt ataagtcccc attgcatcct taaaacacga
     1021 taatacaaaa ctagaaagcc tttatattat tttttattga acgtgcggag catcccctga
     1081 ttcgtatagt tctttcgcct tttcctcccc gaatgtagtt aaaatataat gttgctcttc
     1141 taacgcatcc attgctctag ttgctttaca aacgctatct tcttgagcat ccgagaaata
     1201 attgtgatct tctacaattt tactaaaatc ttttttcacc catctatcag caattgctaa
     1261 aagctcattt ttcttcgcaa agctactctt atttatgatt tcttttaact ttttagcatt
     1321 attttgaacc attgggatag agcccgattt tcgttctgcc accacttttt gatgagtcat
     1381 gtgatgcatc gctataatga cttcgctttc agtagaattt tcagtaacat acacatcaac
     1441 aaagactcca tctacctctc tacctactat cgtttggtct tcttttttgt ctatttgagc
     1501 actcacctct ttatctgctg gattatcggc aagttctaac attccaaatg taactgctac
     1561 agcgagaact cccatagctg ctactattcc taaccaagtt aaaattttat ttttcattcc
     1621 ccttctccct atctatacct atttaattac cttataaaaa actcacttat atgtaatatt
     1681 actaaaaata ggttttattt tccatggtat gaaataatct ctttttctca acaaaataaa
     1741 aagaccaacg aatcataaaa ttcattggtc attgagtgaa aagtttattg gttttaaaat
     1801 tgatattaag tatagatttc aagaatttgt cggcttagct aaagagtaaa cccttactat
     1861 ctttactctc agctagcttt atgttcaagt ctcagcttat ccgcaaccat tgcgataaac
     1921 tcagagttcg taggttttgc ttttgacatg gatactgtat aaccgaataa ggacgaaata
     1981 gaatcaatat tcccacggct ccaagctact tcaatcgcgt gacgaattgc tcgctccaca
     2041 cggcttgctg tggtattata tttctttgcg atatctggat acaatacttt cgtaatcgat
     2101 cctaataatt cgatatcgtt gtataccatg gagattgctt ctcgtaaata catatatcct
     2161 ttaatatgag cgggtacacc aatttcatga atgatactcg taatactcgc atctaaattt
     2221 ttcggttttc catctactgt tgttgctgat cggaatgatg gtagtggacg tttaatcata
     2281 gcatttgctt taccactcac ttgacgaata tgactagtta aattctccat atcaaatggt
     2341 tttaatatga aatatgaggc acctaagtca actgcttttt tcgtcacatc ttcttgcccg
     2401 aatgctgtca acataattac gctaggctgt tttaaccttt caatatgtcg cattttttcc
     2461 aatacagcta aaccatctaa gtgtggcata ataatgtcta aaacgagtac atcaggttgc
     2521 ttatctgtta ataagtttaa acactcttga ccattataag cagtaccgat tacttccata
     2581 tcatcttgag cagctacata gctctctaac attgatacta gttctttatt atcatccaca
     2641 agacatactt taattttctc cacagctttt cctcccttac cgaatcgatt ctccgacatg
     2701 tgtatccttc taggctacat gaattgttcg acaattgtgt gaaaattccc ttttaaagtt
     2761 tcttactttc cgataaaatc acaaaaaaat atgtttatcg ctcatttatt ccctttcgca
     2821 acacattcca tcatagaaat acaacgaaac gttcaaccct tttcttttat tttacaacaa
     2881 aaaacacctc ttgcggagct tttacaaaat ttcaacgaat ttttcaacag aaaaagcgag
     2941 ctaatatgta ttagctcgct tttttctctt gatcataaat attaattcca gcttgatgta
     3001 acatccattc aatatgaaca ccatatcctg atgttggatc atttacaaat acatgtgtaa
     3061 cagcaccaat tacttttcca ttttgtacaa ttggacttcc actcattcct tgtacgatac
     3121 cgcccgtttt cgctaataga cgtttatctg ttacttttat taccataccc tttgtagctg
     3181 ggaatttttg ctgcactgta ctaacgactt caatatcaaa cgcttctact ttatcttgat
     3241 caataactgt taatattttt gccggtcctt cttttacttg atgagataat gcgataggca
     3301 ttgctttatc cattataccg tttttcatat tcgtatttaa ttttccaaaa ataccatatg
     3361 gactattaat tgtaatattg ccaatcactt cacgatctgg tgaaaatctt gctaatttct
     3421 cgcctggatt cccatgactg cctctttcaa ttgatgtaac tgtcgagcgc ataatttgtc
     3481 catcttcgac ttgaatcggc ttttttgtat cattatcaga aataacatga ccaagcgccc
     3541 cgtatttcat agaatccgga tgaacaaatg tcatcgttcc aattccagct gccgaatcac
     3601 ggatatacaa gccaattcga taagacgctt caccattgtc tttttgcggc gttagcttcg
     3661 tgcgaatata ttttccatct cttagcaata caagattaag cggttcacct gtttctccac
     3721 tattatgaat aaacggtgct acatcactca ttctttcaat ggttttacca ttaatttcag
     3781 taatcatatc tccaatttgt acacctgctg tttcaccagg agatatttta cctttttcag
     3841 tttgaattaa atgatggcct acaacaagta caccttttgt atttaatttc acaccaattg
     3901 attgtccacc tggaatcact ttaaaatctt ttaacacttt cacatttact tttttcactg
     3961 gaaaacccgc aagctgaaat accatatcag cttcaccatt ttgatgagaa tttaccataa
     4021 gtccttgttt ttgttcattc gaactcactg taaatacatg acgatttgtg gatgaagctt
     4081 tgaaaactgg taatgatgat atttctgatt gttgtccttc aaaaacaaca agttgtttcg
     4141 gtgatgaaat aaacgttcga agcggtttaa aacatccaat aaaaactaaa gaaacaagga
     4201 gacaaagacc tattattttt cgaaattttt ctaatttcaa cttgttcact ctcctcgctc
     4261 ctaccccaca ttcagcctct tggcttcact ttttaatctc tccttgcaat gctttattta
     4321 taaccggaag aattaagaaa tcgtcatttg agaaaaaaag ctatccatta ctggatagcc
     4381 tctgctgtct gtttaaaatg atgcgcttgc gtaagtaatt ctttcgcatg ctccgtcgtt
     4441 aaatctgtga tttccacacc agaaatcatt cgagctattt ctgttacttt atcctccata
     4501 gttaaaacag taactgatgt aattgtccga tcattcgcta cttgttttcg aataaataaa
     4561 tgcgaatctg ccattgaagc tacttgaggt aagtgcgtaa tacaaagtac ttgcgagttt
     4621 actgatactc gataaatttt ttcagcaata gcctgtgcga cccggccact tacacccgta
     4681 tccacttcat caaaaataac agatgcaacc ccttgatgct tagaaaaaat gctttttaaa
     4741 gctaaaatga tacgagataa ctctccgcca gaagcaacct ttgaaagtgg ttttagcggc
     4801 tctcctgggt tcgtcgaaat ataaaattcc acatgatcgt aaccatccgc cgtaagtctt
     4861 accggtgcac cttctacaag gggttcttct gcatttcctt ctctcttcat aattctcact
     4921 tcaaatttcg ttttttccat atataattct tttaattcct gatgaattgc atttgtaagg
     4981 tgttctgcaa gctcatgacg catattactt aacaacgttg cttctttcag aataacactt
     5041 tctaattcct tcaactgttt cttcgtcgtt tcaatatgaa cgtctttatt ttcaattgta
     5101 aatatttctt gttcaatttt atctgcatac gctaaaatct cttctacagt atttccatat
     5161 tttctcttta gcatacgaat ttcattcaaa cgtgtttcga tttcatctaa acgatttgga
     5221 tcatattcca tcatatcgag cttttctctc agttgatatg caacctcttc taataagtaa
     5281 tagctatttg caattgaatc atgattctct tgatacattt catctaaatg tgtaatactt
     5341 tccatttgtc ccattgcgct tcttacatta tctaatcctt gtccgtcagc actcaatgaa
     5401 cgatatgcat cacctaatgc tttataaatc ttttcaaaat tagaaatttg caatcgttcc
     5461 tcagttaatt cattttcttc atccatcttt aaatcggctt tgcgaatttc ttcatgctga
     5521 aattgaatta aatctaagcg atgtgccatc tgttgttcat tttcacttaa cgatttcaat
     5581 tgttttttta atttttcata gtcagcgtat acgttttgat atatgtctag ttgtttaacg
     5641 attcgatccc catcaaagtg atcaagcata aacagatgtc gttcttcatt cattaaatct
     5701 tgcgtttcat gctgtccatg aatatcaaca agtgttttcc caatttcttt taatatgcta
     5761 agtgtaacaa gcttcccatt tacacgacat acactcttcc cgttcgcagc aatatcacgc
     5821 tttaaaataa tcatgccatc ttctatttct atatctaact cttctgcctt ttcaatacat
     5881 ggatgcttat catcttcaac ataaaacagc ccttcaatct cagccttttc tgttccatat
     5941 cgaacaaatt ctgctgaccc acggccacct acaagtaaac taatcgcatc aataataatc
     6001 gattttccgg cccctgtttc accgcttaaa accgttaaac ctttttgaaa agaaatattt
     6061 aatgcttcaa taatagcaaa gtttctaatc gataattccg ataacaatgc cccattcacc
     6121 tcgttataaa ataatccctt actaaaggat tttctcagtt cttcattcaa ataatcatgc
     6181 tatatatttg tatgtatata ctcttctaac ccgcttcatt gtaccaaaca tttgttttac
     6241 gggtcaatcc atctattttc taactttatg caaacaaaat attatattac aattgaaaaa
     6301 tcatattttt gaccaataaa aatatcttgt tcacttccca ctttacgatg gaaagcaaac
     6361 aagatttttt gttacaacat atttaagaaa cgatcagaga caacacctgt atcgtcaggt
     6421 gtacggcaaa taattaagca agtatcatca ccacagatgg ttccgatgat ctcatcccac
     6481 tctaaatgat caataagtgc tccaagtgaa tgagcgttac caggcaatgt ttttagcaca
     6541 agcatatgtc ctgccgtgtc taattttaca aatgaatcca ctagatttcg ttttaatttt
     6601 tgtaacgggt taaatcgttg atctgctggc aagctatatt tatagcgccc atcatgtaat
     6661 ggcaccttca ctaagtgcag ttctttaata tcgcgcgata ctgttgcttg cgttacatta
     6721 aatccctcat tacgtaaaat atcaactaat tcatcttgtg tttcaatttc tttgtttgca
     6781 ataatttccc tgattttaat atggcgctga cctttattca tacatttgca cctcacacta
     6841 tctcttacca tagtttaaac attggtatac ttcacttatt tatgttaact tataattcgt
     6901 ttcttgtaca caattgtttt tacaatcatt atacaattac agcaaaaaga ggaacaacat
     6961 atgttattcc cctttccctt tttgttttag aacgtcatgc gcttctgtaa caacttgctc
     7021 tatagaaatc ggagaatgat tttcgccatt ctcacgttca ccatgccatt tcagatgaat
     7081 taaaaattca atattaccat ccccacccgt aattggtgag aatgttaaac cttccacatc
     7141 atagccctct tttaaagcaa aatcgacaat catctctaca acagcttcat gtacttttct
     7201 atcacgaacg ataccttttt tcccaacttg ctctcttcca gcttcaaact gcggtttaat
     7261 taacgctgct acatctccgt taggcataag cattgttttt aaaactggca gtataagctt
     7321 taatgatata aatgaaacat caatacttgc aaattgaggt aaaccacgtt ctaagtctgc
     7381 tggtgtcacg taacggaagt ttgttcgttc cattacaaca acacgctcat cttgacgtaa
     7441 tttccacgct agctgattgt atcctacatc taatgcataa gataatttcg ctccattttg
     7501 aagcgcgcaa tctgtaaagc caccagttga tgaaccaata tctatcataa ctttatcttg
     7561 taaatcaaga tgaaatgtct ctaatgcctt ttcaagttta taaccaccac gacttacata
     7621 cggcataact tgtcccttca ccgtaatctc agtatcttgc gagattttct ctcctggctt
     7681 atcaagtctc atctcatttg catatacgag tccggccata atggcgcgct ttgctttctc
     7741 acgcgtttct ataagtcctc gctctactaa tagtacatct actctttctt tttttacgct
     7801 catttgttac gccctttttt gttttgatgg aatcattgta tgaatacggt ctacaacagc
     7861 atctgtcgtt aaaccaattt cttctaataa ttttgttaca cttccgtgct ctatgaagcg
     7921 gtctggaata cccattcgtt caactaatgc actatggtaa ccattttcag atgcaaattc
     7981 aactactcct gttccaaaac caccgattaa acaagcttct tcaatcgtta aaatcggtat
     8041 attcttccct agaagatcat gtaaatatgc ttcatccatt ggtttaataa agcgagcatt
     8101 cactactttc actgaaaccc cagctttttc aagacgctca gctgcttcca ttgccattgg
     8161 tattgtcgta ccaaacgtta aaatagctgc ttgtgtaccc tcttttaacg tctcccacgt
     8221 accgattgga atcgccttta attcttcatc catatgaacg ccaagtccat taccacgagc
     8281 ataacgcaat gcgattggtc catcttcata ttgcatcgcc gtataaacta aatgttgccc
     8341 ttcattttca tctttcggca tcataagcac catattcggc aagtgacgta agaatgagat
     8401 atcaaatacg ccttgatgcg tttcaccatc tgctcctact aatcccgagc gatctattcc
     8461 gatgaaaaca tttaaatttt ggcggcatat atcatgaaca acttggtcat atgctctttg
     8521 taaaaatgtc gaataaattg ctaagaatgg cttcattcct tgcgttgcca tacctgctgc
     8581 cattgttgta gcgtgctgtt ctgcaatacc tacatcaatc atacgatctg ggaattcttt
     8641 ttggaatttc tcaagttttg atccaacagg cattgcaggt gtaattgcta cgatacgctc
     8701 atccgctctc gctagcttaa gtactgtttc actaacgaca gcactccatg ctggtgcaac
     8761 ttcttttggc ttaacgaagt cacctgattc aattttataa ggtcctgttc catgccaagt
     8821 tccaataacg tcactctcag ccggtttata accttttcct tttttcgtaa taacgtgaac
     8881 aagtactggg ccttttgttt tctttgcata ttgcaacgtt tcgaataact tttcataatc
     8941 atgcccatcg actggaccta aatatgtaaa gcctaactct tcgaaaaaga caccagatac
     9001 tagtaaatat ttaagactat cttttatttt ctctgctgtc gcagccactt tcccgccaac
     9061 tgctgggatt ttctttaata tatactctaa ttcatctttt acccagtgat attttcctgc
     9121 ggtacgtaaa cgaccgagta cattatgaag cgcaccaacg tttggtgcaa ttgacatttc
     9181 attatcattc aaaataacaa tcatgtctgt tttttcatgt ccaatatggt tcaatgcctc
     9241 taaggccatt ccacctgtta aagcaccatc tccaataatt ggtataacat attctttcgt
     9301 tttctttaaa tcacgtgcca gagccattcc cattgcagcc gataacgaag tcgagctatg
     9361 accagtttcc catacatcat gctcactctc gcaacgtttc gggaaaccac atagaccttg
     9421 atattgcctt aatgtaccaa actctttcgc gcgtccagtt aaaattttat gtacatagga
     9481 ttgatgtcct acatcccata aaaatttatc ttgcgggcta tcaaataatt tgtgcagagc
     9541 aattgtgagt tctactacac ctaaattagg tgcaatatgt ccacctgttt gagagagctc
     9601 ttcaattaaa aacttacgaa tatcctcact caatccctct agttcactga tagacatatc
     9661 tttcaaaaaa ctagggtttt gaatttgcgt tagatccaca tggatcactc actttcattt
     9721 cataatctgt caacatgtca aatattataa aaaacattta cacaaaacaa gaaattctct
     9781 tttctatttt tcgtcttgtc ccgctattaa ccagtctatt gcgccttaat cctattataa
     9841 accatatttc tttaggcgat gaaaaaaata gccgctaaca cgaagtgata acggcaatgt
     9901 aatctacata tatttttgcc aataacaaga aaagaaaaac cttttcctac atttatatca
     9961 taaaatgatg aatgactcaa caaatgaaaa cgctgttata ttagttatta cgttttgcaa
    10021 tcaaatcgca aatagatagt aaatattcat cttgtaattg caaggagcta attgcacctt
    10081 ttgcttctgc aattgtttct tctaaaatat cctttgctct atctacagta aacaacgtcg
    10141 tatatgtgct cttttcatta gaaagatcgc taccaatcgg ttttccaatc tcttcttcgg
    10201 tgccttcgac atctaaaata tcgtctcgaa tttggaaagc tagaccgata tatttagcaa
    10261 acgtaagcaa cttttcttct tgctcttctg tcgcatcaga aagtatcgca cccgcaagta
    10321 cagcaaattc aagcagtttt ccggtcttat gtttatggat gtactccaat tcatcaatcg
    10381 taaggcgttt cccttcagct tccatatctg ccacttgtcc gccaaccatt ccttctggtc
    10441 ctgctgcttt tgcaagttca agtacaagtc ttactttttt ttctgcagaa atttcttttt
    10501 gctcatatgc cataataact tgaaaagcat acgtcaacaa gccatctcct gctaaaactg
    10561 ccatcgcttc accaaatact ttgtgatttg tgggctttcc tcttcttaaa tcatcatcat
    10621 ccatacaagg taaatcgtca tgaactaacg aatatgtatg aatcatttca agagcacaag
    10681 ctgcacctac tccaagattt ctttctttcc caaaagcttg taatgttgca aacaaaagta
    10741 acgggcggag acgttttcca cccgcttcta aagaatatgc catcgcttca cgaagtacat
    10801 ttggacattg taattcattt gcatagctta caagtttctc ttctacgaaa gttttacttt
    10861 ccttcaaaaa agtatcaaaa gcaatcgtca ctatgcttca tctcctaaag cagtaaacgg
    10921 ttcaagctct ccatcttccc caagaataac tgccatttgt tcttgtacat tcttcaactt
    10981 ctcatcacaa agcttagata attccatacc ctctttaaaa taagaaatcg cttcttctaa
    11041 aggtacgtca ccttgttcta gcttagaaac aagatgctca agttgcgaaa ttgcctcttc
    11101 aaagcttaat ttattttcca ttattcaatt cacgctcctc tatgcctgat acgctacaat
    11161 ctagtattcc atcttgtaat tgaactgaaa cagcatctcc aaggcttaca tctttcacac
    11221 tttttaacac ttgcttctct tcatcatata caagcccgta ccctctcatc attactttaa
    11281 gcggacttaa cgcttcaagt ttttgagcag ctcttacaaa ggcaaattct ttcgtttgaa
    11341 gtaacgtttg catttcacgt tgtaattgct tttgcaacgt ttcaacagct accttcgttt
    11401 gaataatttt ttgagatggg tggtgcttct ctaaataaaa tgaaagttgc tttaactgat
    11461 tcaccttttt atcaatatag cgttctttcg ctaaaacaag ctgttctagc gctctatcta
    11521 attgctcttc cttttgctca tatacttgtc ttggataacg gaacgcatac gatttttgca
    11581 acacttgtag tttttcttct tttttatgta ctaactcttt cattgctctt tgcaatctca
    11641 gagttctttg taataccttt tcttgtaact ctataatatt aggtgctgct agctcagctg
    11701 ctgcagtcgg tgttggcgcg cgtaaatctg caacaaaatc tgcgattgta aaatccgttt
    11761 catggcctac tgccgaaata ataggaattt cactcttaaa gattgctctt gcaaccattt
    11821 cctcattgaa agcccataat tcctcaatag aacctccacc acgaccaacg attagtacat
    11881 ctatctctcg catttcattc gctgtacgaa tcgcttgtac aatcgaggga gccgctgact
    11941 ccccttgtac aagtaccgga aatacaataa cattcccaat tggataacga cgtttaatcg
    12001 ttgttataat atcacgaatc gctgctcctg ttggcgacgt aatcacacct attgttttag
    12061 cgtaaggagg aattgctttt ttataaactt gagaaaaaag tccttcttct tctaagcgaa
    12121 cttttaactg ttcgtacgct aaatgtaaat ttccgactcc gtcaggctgc atgtcttgaa
    12181 tataaatttg ataagaacca ctcgcctcgt aaacagagat tttccctttc acgagtacct
    12241 tcatcccatt ttcaggtttg aatttaatat tacgattatg acccgcaaac ataaccgctg
    12301 cgattcttgc attttcatct ttcaatgtaa aatacatgtg gccacggcta tgatttttaa
    12361 agttggaaat ttcacctttt aaccaaacag actgcaaatg cggatcatat tctatttttg
    12421 tttttatata gcgtgttaac gctgtaacgg ttaaatattg cttctccatt tctctctcct
    12481 catagccgac tcaaattatt tacaaacgac acctgcacgt ttggcagatt caacagtatt
    12541 atgaagaagc attgtgattg tcattggacc aacacccttt ggcacaggtg taatgtaacc
    12601 cgcaacatct aacacgttgt caaagtcaac atcaccacaa agttttcctg tttctaaacg
    12661 gttaacacca acgtcaatta caaccgctcc ttctttaata taatccgctg ttatcatttt
    12721 aggtcgtcca acagctacga ttaaaatatc agctaacttc gataactctt tcatattttg
    12781 cgtcttagaa tgacaatatg tgacagtggc attttcattt aaaaacaatt gccccactgg
    12841 tttaccgaca atattacttc ttccaattac tactacatgt tttccagaaa tatcaagatt
    12901 tgtttctttt actaattcta caataccatg cggtgtacat ggaaggaatg tatcttgtcc
    12961 cgtcatcata cgtcccacgc tgattgggtg aaatccgtct acatcctttt ctggtgaaat
    13021 tctttcaatg atagcttttt cttcaatatg ttttggtaaa ggtaattgca ccaatatgcc
    13081 attaatacgg tcatcgccat ttaagcgatc gatttcagca agcaaacgtt cctcagtaat
    13141 tgtttcagga agttcaatta gctctgagta aatccctact tgttcacagc ctttttcttt
    13201 tcctttcaca taagaacgag atgctggatc ttctccaact aaaataactg ctaaccctgg
    13261 tacaatacct tgctctttca acttcacaac ttcttctgtt aattgtgctc gttttttctc
    13321 cgcaacttca tttcctttga tgattactgc taccatttta agattccccc ttaaagaatt
    13381 tacagtgtat cttttatatt agataaaacg ccgttaataa aacgacgaga ttcctcatcc
    13441 ccaaatgttt tagcaatttc aattgcttcg ttaattgtta cgttgtgtgg aatttcttcc
    13501 atgtatttca tttcatacac agctacacgt aaaatactgc gatcaacaat gctaatacgc
    13561 tcaagcttcc acttttttaa gttttgacga atcgcttcat cgattgcttc tttattttct
    13621 acaaaaccta ctacaagtga ctctagaaac tcatttgttt cttcgccttc atctagcgtg
    13681 ttttccactg ctactttcgg ttctaattca cctgtaatat ccatttggta taatgcttgc
    13741 attgctcttt ctctagccgt cctacgtttc attgtaactc tcctttatgc ttcaagtctt
    13801 tccttatact ttgttatatt attataattt ataagccgtc aattcactta ctcttacagt
    13861 tttcattgat tttccaacct tataatacaa tgataataac acaatttatc gtttcacaca
    13921 cgggttacaa ggctgaaaaa taataaaaag attaacttca agttccatat cttatcacaa
    13981 tgtacgtttt ttggaaaaac gacacatttc cttgtttatt tcttattttt tgaaatagta
    14041 taataattag agggttgtaa tttgtgaaga aatgaaacga taaaaaagat gcctatgtta
    14101 ctaggcacct tttcattctt acactggttc gatttctgtt ttttgtgttt cgaatgttac
    14161 gccaacgatg tgaacattca cttcttttgg ctcaagtcct gtcatcgtaa agagtgcttg
    14221 gcgaatattg tcttgaatct tttgtgcaac aactggaatt gctacaccaa aatacattac
    14281 aacataaagg tcaacgataa tatcttcgtt tgctaattca acctttacac ctttaccatg
    14341 atttttctta cctaacttct caacaacatc tgtagcaaaa ttaccgcgca ttgccgctac
    14401 accttctact tcagcagctg caatacctgc aattacttca attacttctg gtgcaatttc
    14461 tactttacca agagttgtat cttgacccat atctaacata tgttcagcca tgaaaaaaac
    14521 ctcctttaat gtatcactgc gtcacaagtt catgctcttc caaaaatttc gtattaaact
    14581 caccttttac aaaatcagga tgatctagca attgcaaatg gaacgggatt gttgtatgta
    14641 cgccttcaat gacaaattca ctaagtgcgc gcttcatttt tgcaattgcc tcttcacgtg
    14701 tttttccgtg aacaattaat ttagcaacca tcgaatcata gaaaggtggg attgaatatc
    14761 ccggatatac agctgaatcg acgcgaatac caaatcctcc tggtggtaag tacatttcta
    14821 ctttacctgg agatggcata aattttttgg cagggttttc cgcattaatt cgacattcaa
    14881 ttgcccaacc attaaattgt acttcttctt gctgtaacga taacttttct cctgaagcaa
    14941 caagaatttg ttctttaatt aagtccattc ccgttaccat ttcagtaacc ggatgctcaa
    15001 cctgaattct cgtattcatc tccatgaaat aaaaggtttt cgttttatat tcataaataa
    15061 actcaaccgt accagcacct gtataatcaa ccgctaccgc cgctttaact gccgcttcac
    15121 ccatctgctt gcgaatatct tcatcaagtg caggtgatgg actttcttct aatagttttt
    15181 gcaaacggcg ctgaattgta caatcacgct ctcctaaatg aatggcattt ccgtgtgtat
    15241 ctgccattat ttgaatctca acatggcgga aatcttcaac gtacttttct aagtatacac
    15301 cagggttccc aaaagcggta ctagcttctt gctgtgtaat ttgaattcct tttataagct
    15361 cttcttcatg gcgtgcaaca cgaatacctt ttccgccgcc acctgcagtc gctttaataa
    15421 taactggata tccaatttga ttagcaagct cgatcgcttc ttcggtattt ttaataatcc
    15481 cttgtgaacc tggtacaatc ggaacccctg cttctttcat tgtatcacga gcaacgtctt
    15541 ttgtgcccat ctttgaaata gcttctggac ttggaccgat aaaaatcaag ttacattcac
    15601 ggcataactc tgcgaaatct gcattctctg ctaaaaatcc gtatcccgga tgaatagcat
    15661 cgcagcctgt taacttcgca acgctaataa tgttcgtcaa atttaaatag ctttctttcg
    15721 aaatcgttgg tcctacacaa tacgcctcgt ctgcaatctg tacgtgaagt gactctttat
    15781 ctgcttctga ataaattgca actgtttcaa tatccatttc tttacaagca cgaataattc
    15841 gtacagcaat ttccccacga ttggctatta atactttttt tatcatcaca aagactccct
    15901 tattacgctt ttacaagaaa tagcggttgt ccatactcaa caagctgtcc gttattaaca
    15961 agaatttcaa caatttcgcc ctctacatca gcatcaattt cgttaaataa cttcatagcc
    16021 tcgacaatac atacgataga atctttcgat actctatccc caacacttac atatggaggt
    16081 gtatcaggtg aagaagaaga atagaatgta cctaccattg gtgaggtgat cttatgtagg
    16141 ttttcatctt gaacagtttt cttctcttct tgttttggcg cttctgcttg cgctgctgct
    16201 actgtcgttt caacttcaac aggcgctact ggttgcatag cttgttttgc tgcaggtgct
    16261 tgcacagcaa caacttcatt accacgcttt ttcattttga ttgttgtacc gtcttttttg
    16321 tattcaaatt catcaatatt agagctatca attaatttaa ttaattcacg aacttcttga
    16381 attttaaaca tgtaaaatcc actcccatac tcttgtttgt cccgttttta cagattctcg
    16441 tcacgaaaac tagattgact gtaaaaatac gatgtattct attagaaaat atatttcatt
    16501 aactaataga aatatttact atttccatct tacgataaat tttttaaaca ttccaattta
    16561 tatttcttta taataaatcg aaactcctgt aaaaatatta ttccaataaa aatttaatac
    16621 ctagtaataa taccaagttt cacatgaaat tggcaagacc acttcttaaa aaacattcac
    16681 tactttagca aaacgttaca cagcaaacat gccattccct ctccactctt cactacacct
    16741 atagtcaata acatattttt accaaatatt atttttttgt ttacacgccg ttcatcattc
    16801 cttcatataa gaatagtatg ttcaaagtgt agaaaatata ttgtgtcgag gtgtggaaat
    16861 atgatatggc tcattctctt tttacctgct gtaatcgttt gggcatgtgt tctttgcatc
    16921 cacgtcaaat ccggaaaaag taatcatcag taccatgaac cattaatctt ttactcgcaa
    16981 cgtgtttctc cattccgagt tgaacatagt aaaaataact acaaagacga aatagaaaaa
    17041 agctatcgaa aatgatagct tttttctatt cacacattta cttacatact ctattttact
    17101 atttgcatac cctttgctta gtaaaagata ataatccgca gggaaatccc tgcggattaa
    17161 agtttcactt atttcgctgg tggatcaaat ttcacaccta catcttttga tccgccttca
    17221 cttcttacaa gttgaataat tttatttgct tctttctgtg aatgttttgc cgctttaacc
    17281 gttactctaa tgtcagtacc atcagctctt acaagagcat ctggatatcc tccttgagat
    17341 ttaattactg tctcaagtaa ttcttgcttc gtttccattg tcgtaatggc atcaaaattt
    17401 tcttttgctt tattcttttc tgttgctgaa gcttttgttg aactcatcac ttcttgtaat
    17461 tttgcttttt gttcactacg ctgatcttcc atttgcatac gtaaagctgt gaaattctca
    17521 tcacttgatt gaactgatac attgccctct tttttacttg tttctttttt tgcattttct
    17581 tttttgtctg tttctttatt tgttgtttcc ttgcttgtat tttctttttt cggagtttct
    17641 ttaggcgctt cgtttgttac tgctttatca gtaccttgtt tttcttgtcc aatcttttca
    17701 cctgttgccg gcgatgctgt attcattttg tcaggagttg tcacgtaata cacagatagt
    17761 acaacaacta aacttaacat cgttaataac caaactgttt gtttttttaa cactttattt
    17821 cctccctatc aatttttcgg tgaaactgaa acgcgatggg ccggtacatc tagcagcctt
    17881 atcacagctt cttttaccat tgctttaact tgtatattat ccactccctt tgctacgaca
    17941 agaacaccac gtactttcgg cttctctgtt cgtaaaacaa caggagtttc tttatcccct
    18001 tcacgtataa tgacagtctt ttcatcaaga gactcgtcct ctacttctct cttaccgcct
    18061 gttttatctg tttcacctgt tgtttgtgag cgtttcactg tatttttttc taaaattttt
    18121 tcttcagatg aatctaaatt cactttaatc gttacgtctt ttactcctgc tatttcttct
    18181 aaagcagttt ttaattcttg ttcatacgct ttttcatatt tttctacatt tgacatacta
    18241 tcattacttt tttgtccgaa agttggtacg tctttttctt gattttgagt tttttgttct
    18301 ttaaatacag gtacttcttc ttttttactt gaaaagagac tactagaaaa cataagcaaa
    18361 attccaagta tgagtaggac aagtaaaaac ttaggtgtta cctttttacc cttctcgttg
    18421 ctttcttttt gatccccatt caataagttt cgaaaaaatg agaacttcga atttttatct
    18481 ttattgtcca tttactctac ctgtcctccc ttccatttga acttggattt gtttaccctc
    18541 tagttgccac ctgcttgaaa agaaatcttt catttctaca ttcgtttctt ccactttttt
    18601 tggcggctct ttcgtgttaa tttcaattgg ctttactgtt tcgattgcat catttttact
    18661 acgttctttt tctttcaacg tcacaacaac agattgaata tctttcgctg actttacttc
    18721 ttctgtattt tctgctgcga ctatttgtat ttcagagaca gtcataccat actttttctc
    18781 aaactctttt cctacttctt ttttcatttt ggtagccatc tcttctaaac tatatgcacg
    18841 tgttagagct tgtatttctt ttttcttcga atctattgaa ttttttacag atccttctgc
    18901 tacgtacttt tcttcattaa aatttgcaat tacttcattt acatctgtct gcaatagttt
    18961 aaaaaggggc gttaaaatta atacaactaa caaaagactt acaacgaatt taacgtattt
    19021 ttgcaaattc gaatttggaa gaataagatg aagcattgtt gctaagagca aaaaaacgat
    19081 aatatttctg atccactctg taacaaattg catactcttc acctcctacc gcatcataag
    19141 tgtaatattc cccgcagcaa taataattgt aatacttaaa aagaacataa atgatacgat
    19201 agctaagcaa gcaaatacgt aaatgatgct tcgtccaata atgtctaaac attgaataat
    19261 tgctccgccg ccaaccggtt gcaatactgc tgctgcgaat ttataaataa atgcaataca
    19321 gaaaatttga atcgctggaa aagcaacaat taagcataaa atgacgagcc caataattcc
    19381 gactgtgttt ttcaataatc ctgatgcgct aataacagta tctgccgctt ctgtaaacat
    19441 ccttccaact actggaatga agtttcctgt tacaaattta gcagttttca cagctattcc
    19501 atcagcaaca gctgttgctg tcccttgtac agataatact cctaaaaaaa ttgttaaaaa
    19561 gacaccgata atccctacgc taacgttttg cagaagcttg gataatttcg tcactttata
    19621 ttgatcactc attgtactta caatacttaa tatcgttgcc agtaataaaa gtggtagaac
    19681 gatataattc ataagaagcc cactcgtatt cattaagaaa atgataaccg gatgaaaaaa
    19741 tgatacagat acaaccccgc ccccagttgc tataagcgcc agcaaaattg gcaataacgc
    19801 taatatgaaa tctaccattg tttgtatcgt ttctcttgca tatgtcataa cgacataaaa
    19861 actatttaaa gcaaaaataa taagtaccat atacacaaca gcatcagcaa ttttacttac
    19921 gctacttttt gaaaaagcgg attgcagtga ttgcaacaat gcactaaaga ttgtgagcat
    19981 aataagtgtg ccaagcagtt ttccattagc agcaagctca tgaaataaat attttaataa
    20041 ccctatcatc cactctttta gagagaattc tttttctccc tttacaaact ccataaagct
    20101 ccctttttga ctctctggca aatagcctcc atattttgta acaagcccgt cccaaaattg
    20161 cttcacatct tcaattccga gcttatccaa ttgttgatca acgacgtttg tttctacagg
    20221 agaagcttgt acaacaaccg gtaaagaaaa gaaaaggaag caagcaaata gcagcttagc
    20281 tccaaacctc ctcaacattc actccccctt atcccgtcgg taaaaatccg agaatagttt
    20341 caattacaac cgtcaaaata ggaatcgcca taacgagaat taagattttc ccagcaagtt
    20401 caattttcga agcgatggca ccttgaccag catcttttgt aatttgggct ccaaactcag
    20461 caatataagc aattccaata atctttagta acgtttccac gtagacgtta ctaactttcg
    20521 cttcacttgc tactctctca atcatttgta aaatagaatg aatttgatcg attaaaataa
    20581 gaaacatcac gctacctacg aacacaataa ataaagatgt aatactagat ttatgctgat
    20641 tcaaaacagc agctaaaaac gtagcaacga ggcctaatcc gacaatttgt ataatttcga
    20701 ttcgaaccgc ctcctttact ggaagagaaa gacactttta atcttgtcaa atagcgtgtt
    20761 aattaaaaat gcaacatgaa ataaaatgac gacaaaaccg acaaggataa cccaatttgc
    20821 aatatcctcc cgctttaatt cttttagtac agtatgaatg aaagctaaaa caatgccgat
    20881 tccggcgatt t
//
