LOCUS       NZ_CP045606            23507 bp    DNA     circular CON 16-FEB-2024
DEFINITION  Bacillus cereus strain SB1 chromosome, complete genome.
ACCESSION   NZ_CP045606
VERSION     NZ_CP045606.2
KEYWORDS    RefSeq.
SOURCE      Bacillus cereus
  ORGANISM  Bacillus cereus
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 5461537)
  AUTHORS   Batinovic,S. and Petrovski,S.
  TITLE     Bacillus cereus SB1 complete genome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5461537)
  AUTHORS   Batinovic,S. and Petrovski,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2019) Department of Physiology, Anatomy &
            Microbiology, La Trobe University, Kingsbury Drive, Bundoora,
            Victoria 3086, Australia
  REMARK    Sequence update by submitter
REFERENCE   3  (bases 1 to 5461537)
  AUTHORS   Batinovic,S. and Petrovski,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2019) Department of Physiology, Anatomy &
            Microbiology, La Trobe University, Kingsbury Drive, Bundoora,
            Victoria 3086, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: NOV-2019
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 46x
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/16/2024 03:34:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,375
            CDSs (total)                      :: 6,221
            Genes (coding)                    :: 5,991
            CDSs (with protein)               :: 5,991
            Genes (RNA)                       :: 154
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 107
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 230
            CDSs (without protein)            :: 230
            Pseudo Genes (ambiguous residues) :: 0 of 230
            Pseudo Genes (frameshifted)       :: 89 of 230
            Pseudo Genes (incomplete)         :: 140 of 230
            Pseudo Genes (internal stop)      :: 70 of 230
            Pseudo Genes (multiple problems)  :: 57 of 230
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:27:55
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1205025
            Orig. end                         :: 1228532
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP045606.2.
            On Dec 19, 2019 this sequence version replaced NZ_CP045606.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Steve Petrovski, La Trobe
            University, Bundoora, 3086, VIC, Australia.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23507
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="2"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..23507
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23507
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13507](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13507)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     misc_feature    complement(152..170)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 24.43"
                     /tool="antismash"
     gene            200..559
                     /locus_tag="GE376_RS06120"
                     /old_locus_tag="GE376_06255"
     CDS             200..559
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016082428.1"
                     /locus_tag="GE376_RS06120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_06255"
                     /product="DUF4029 domain-containing protein"
                     /protein_id="WP_000946150.1"
                     /transl_table=11
                     /translation="MLRRKLLYLLLTVPLYAWLISMTKIELMALFLGYVFIFSNLNRIQ
                     EQSILEICLFSISIELFSIVSIVLLNELFLRIHSFTLMKFWNIALQAICTYIVFVVLKK
                     IIGQQTVFQDNRKWE"
     misc_feature    complement(567..581)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 18.41"
                     /tool="antismash"
     misc_feature    568..582
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 18.76"
                     /tool="antismash"
     gene            674..2173
                     /locus_tag="GE376_RS06125"
                     /old_locus_tag="GE376_06260"
     CDS             674..2173
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015129 - lactate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015727 - lactate transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002126004.1"
                     /locus_tag="GE376_RS06125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_06260"
                     /product="L-lactate permease"
                     /protein_id="WP_097984426.1"
                     /transl_table=11
                     /translation="MAILLALIPIMMIFICLFLFKQTSLRSALISYAVCVGIVLLSPTF
                     QLGISETVHATIKGWLICFIVGYVLFFGIFLFHLMNKMGYIDQVARFLEEVTHDRLLQM
                     LLMCFGICPLIESVSGFGIGFMVAAPIFLSLGYKPFQAVLLSFIGLLASSWGAMATGTI
                     IGSQLINMPLTTLGTNTALLSIPMFAYFVILSLYVVGGWQAVIEKWKEGVGFFLLFSLG
                     IYLSNAYVSVELAGILSSIVTITFGFLIIKLKGKSEQNLITEHAAATEREVSIIKIISP
                     YIFLTVCILLSRLVPALHDLFRSYAVLDLKSYSYKLELLYSPGFWLGMTCLFTIIFFRI
                     PSNIIKQSLSQTIKQWIPFAITTTMFIAISELMGASGMHLLLAKIAGETFGTFFVFFAP
                     FIGAIGGFLTGSNAGSNAMFIKLQMQTAQNVALPWQYVTTLQNTASSVATIACPSRITL
                     GAYLCNIPYRENELLKKTTLMIFGAVLLVMVEVIVWYMLRN"
     misc_feature    complement(703..718)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.85"
                     /tool="antismash"
     gene            2264..2947
                     /locus_tag="GE376_RS06130"
                     /old_locus_tag="GE376_06265"
     CDS             2264..2947
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001128612.1"
                     /locus_tag="GE376_RS06130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_06265"
                     /product="YukJ family protein"
                     /protein_id="WP_001128611.1"
                     /transl_table=11
                     /translation="MPLKNYGVLKGTVIQSKIGKGKTPHYQVHLQGETGVDYRIAINVK
                     SQSYPSEVLYFASNNIRSEAIHILPTLPFGFTEVKNNEPKVALDYVRGNLFDSKQMIPL
                     PPEKAGADNDLNEKIERYIKRAMEEKAIIYAFGERWGPEENTPDSYFHFKPGNGIHDIH
                     MNQGNVEKWQGDDGIWQDGGILIHFEKEEEWIGIFLAFQSQSWCTDEEGHARVPVEHCD
                     YKGNN"
     gene            complement(2962..3795)
                     /locus_tag="GE376_RS06135"
                     /old_locus_tag="GE376_06270"
     CDS             complement(2962..3795)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017762920.1"
                     /locus_tag="GE376_RS06135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_06270"
                     /product="hypothetical protein"
                     /protein_id="WP_000424522.1"
                     /transl_table=11
                     /translation="MELVNSIFQILLTSVIQLLSLIGVIIVIGFLLGYLESLTRMYWSR
                     AFGRKGFLLTAWIGVPIHELGHAIMCVLFRHKIVATQFFPTDTSQGALGYIQHQYNQKS
                     VYQRIGNFFIGIGPIISGITALILLMRYFVPESYFLFNTTLEKTIASTSINVEMIQNML
                     LSTFVLLKSLFTIGNLLNPSFWLFLFIAICISAHIALSKPDIKGSIDGVVVMFIVLFLF
                     NIIAGLFQYDSNQLIGQVMKYNMYLIAFSSVALLFSCLSTLVSFSFYKIRRGRSF"
     gene            3992..4777
                     /locus_tag="GE376_RS06140"
                     /old_locus_tag="GE376_06275"
     CDS             3992..4777
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000650096.1"
                     /locus_tag="GE376_RS06140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_06275"
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="WP_153217605.1"
                     /transl_table=11
                     /translation="MKCPSCHTKNAVEAKFCGNCGHSLTEEVVASSGQEEGPEQARAAQ
                     AKEARPNETVEQAKRFASGYFQFFKHALQAPTAIMKSGAIEVRNGIVSLVLICFLGACI
                     FYRMMSAASAVTRTFAPDISTPTFFGESITVFFFLLILTLFVGFIIFVSGKMMKSSFSF
                     LEVFGIWGTIATPAIVILVLSFLFSFLLIFFLPILLSVVATYIGISITVAVLKLDNGGL
                     DLVYTLIIANVLIGIATFIVLWSYISTIIQALTQGITGF"
     gene            4797..6032
                     /locus_tag="GE376_RS06145"
                     /old_locus_tag="GE376_06280"
     CDS             4797..6032
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017672808.1"
                     /locus_tag="GE376_RS06145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_06280"
                     /product="YARHG domain-containing protein"
                     /protein_id="WP_001099935.1"
                     /transl_table=11
                     /translation="MNVCTKCGVQFEDGVQFCQNCGMKRGSPVVKKNMSSGTKVGITLL
                     ALFVIAIIGLYLYGSSYYTQVAQVDRMITILQERDGEKLAEIVTADDPSVMITRENLTP
                     LFSYIKENPAYVNELKEYLRQGEKQRDGIERADFSLTKDGKYFFIFDRYKLKAKTYYTT
                     LLTNEKGVALKMNGKEIDKTDDKKFEKQYGPFLPGNQVFQSEYKNDYVKLSREEKVVLM
                     KQSQNNVTIDLTLQGQYITVQTNAPGATLYVNQKPVTALAGEAITWGPVATDGSAKIYL
                     ERNGENGRETTKLETVTALSSYNLPFQTKSAEKTVVYNVTPTPATGYVYNGFIFPDSDI
                     RKLTSTDLTYLSKEQLKIARNEIYARHGHIFQTKDMQAYFAKQSWYRENPYFTGTLTDI
                     ETYNIELIKSRE"
     gene            complement(6072..6503)
                     /locus_tag="GE376_RS06150"
                     /old_locus_tag="GE376_06285"
     CDS             complement(6072..6503)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000332399.1"
                     /locus_tag="GE376_RS06150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_06285"
                     /product="hypothetical protein"
                     /protein_id="WP_000332399.1"
                     /transl_table=11
                     /translation="MCAGLLAQFPEEPKEPKPALSLDQEFSINATIYSARAWLSNDETF
                     PQTIWKGSRFASASHAGKSILPIGTVKILNLSDDTITVTASSESDDTLKIVVPPHSEGV
                     LTSNALSDVQASTSGGASKVTFLFHIFFSRDPGSDKKKP"
     gene            6704..8038
                     /locus_tag="GE376_RS06155"
                     /old_locus_tag="GE376_06290"
     CDS             6704..8038
                     /EC_number="1.8.1.14"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001110220.1"
                     /locus_tag="GE376_RS06155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_06290"
                     /product="CoA-disulfide reductase"
                     /protein_id="WP_097920389.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 3.4e-65, bitscore:
                     218.5, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYVIIGGDAAGMSAAMQIVRNDESANVVTLEKGEIYSYAQCGLP
                     YVISGAIASTEKLIARNVKTFREKYGIDAKVRHEVTKVDTEKKMVYAEHTKTKDVFEFP
                     YDRLLIATGVRPVMPEWEGRELQGVHLLKTIPDAERILKTLETNKVEDVTIIGGGAIGL
                     EMAETFVELGKKVRMIERNDHIGTIYDADMAEYIHKEADKHNIEILTNENVKAFKGNER
                     VEAIETDKGTYKADLVLVSVGVKPNTDFLEGTNIRKNHKGAIEVNAYMQTNVQDVYAAG
                     DCATHYHVIKEIHDHIPLGTTANKQGRLAGLNMLDKRRAFKGTLGTGIIKFMDLTLART
                     GLNEKEAKGLHIPYKTVKVDSTNMAGYYPNAKPLYLKLLYRSDTKQLLGGQVIGEEGVD
                     KRIDVIAMALFNKMSIHDLEDVDLSYAPPYNSVWDPIQQAARRAE"
     gene            8138..8626
                     /locus_tag="GE376_RS06160"
                     /old_locus_tag="GE376_06295"
     CDS             8138..8626
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002135035.1"
                     /locus_tag="GE376_RS06160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_06295"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_023521444.1"
                     /transl_table=11
                     /translation="MIVALQKVQESEKEILRNLYALYLHDLSKFTMNITIGANGFFEYE
                     DLHMFWKHDGITPYFIKIDHSIVGFLLLLERPFLKKENDFGINDIFILNQYKGKGIGKQ
                     VVENLLEEKRGQYFVIELLKNVPAVSFWKKVYKELNIEFDEREQLIDAEECLVQTFKI"
     gene            8878..9288
                     /locus_tag="GE376_RS06165"
                     /old_locus_tag="GE376_06300"
     CDS             8878..9288
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996799.1"
                     /locus_tag="GE376_RS06165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_06300"
                     /product="DUF3908 family protein"
                     /protein_id="WP_097920390.1"
                     /transl_table=11
                     /translation="MAINMKTIEEWIVESNARHEEDFGHVVEEMKEVCVGLDNATLIYT
                     KNVFCFGKKVEVFFFFQDHVVIGQEKDEYIEIEKLKYDDIINNNLKTNDKNTTLELKFA
                     NGQSINLDSLNDNYGTKNWLFARQIKSIFKLI"
     gene            complement(9319..9909)
                     /locus_tag="GE376_RS06170"
                     /old_locus_tag="GE376_06305"
     CDS             complement(9319..9909)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (48-149). E-value: 1.1e-13. Score:
                     42.0. Matches aSDomain: nrpspksdomains_GE376_RS06170_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016109564.1"
                     /locus_tag="GE376_RS06170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_06305"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_153217607.1"
                     /transl_table=11
                     /translation="MSILQRLIQQAKKPSGTIGSSMLCIMNAAHTRLINWALQKVHIKT
                     DAVVLDIGCGGGKTIHTLSKRTPLGGIYGIDYSDQAVKNSIQTNAKDVQKQKVIVQQAS
                     VSSIPQHTNFFDLITAFQTHYFWPDIEQDIKEVFRVLKPDGSFLLVAETFKIQYHMEKF
                     KTNEELINLFYKTGFTKVQCYEEKGCLCVIGNK"
     aSDomain        complement(9463..9765)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GE376_RS06170_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="1.10E-13"
                     /label="GE376_RS06170_oMT.1"
                     /locus_tag="GE376_RS06170"
                     /protein_end="149"
                     /protein_start="48"
                     /score="42.0"
                     /tool="antismash"
                     /translation="VLDIGCGGGKTIHTLSKRTPLGGIYGIDYSDQAVKNSIQTNAKDV
                     QKQKVIVQQASVSSIPQHTNFFDLITAFQTHYFWPDIEQDIKEVFRVLKPDGSFLL"
     gene            complement(10001..11542)
                     /locus_tag="GE376_RS06175"
                     /old_locus_tag="GE376_06310"
     CDS             complement(10001..11542)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016124293.1"
                     /locus_tag="GE376_RS06175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_06310"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_001175539.1"
                     /sec_met_domain="PF00881 (E-value: 8.9e-09, bitscore: 33.9,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLDTFLHHLHFSIDEIMPNHEVDWKDAPLPYKLYRNVPTIPLSL
                     EIPLSLPNSSTTPTLDEIGHYLWYSFGVTQLCQLNSERNVLRRSIPSGGALYPNELYIY
                     LKIDDYPDGIYHYDVAHHRLILLREGNFDSYLADALGNRCNIHDCFGAAFVSTMFWKNF
                     FKYNNFSYRLQGLDSGVLIGQLLECAKQFGYTNGVYFQFLDRALNHLLGLSEGEESVYA
                     VIPLSTESETNWFHNDYRENKTVTSHELLQQIPPLAHEHFVRSKHVNEHPMITKINEAS
                     MIESTEHFQTLHHEEHYQHNTYAVQLPKVERLSYDFLQLCKKRYSPDADFILTKWDAAE
                     LATLLQEASLSFLYYNDLDGKYINENARVSLYGCFYNVKNIKNGAYAYNSKTHSIQPIR
                     YGDLRYPLQSSMTMDNVNLFQVPLCLHVVGKKDYYTRALGYRGYRIHQMEAGILVHKLV
                     FAATAMGMGGHPLLSFDTNSCDQLYGIDAGNETSLIQVPVGAYRARNWLKGALHN"
     gene            complement(11558..13507)
                     /locus_tag="GE376_RS06180"
                     /old_locus_tag="GE376_06315"
     CDS             complement(11558..13507)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191877.1"
                     /locus_tag="GE376_RS06180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_06315"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_000197742.1"
                     /sec_met_domain="YcaO (E-value: 7.9e-84, bitscore: 280.5,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 1.1e-141, bitscore:
                     470.4, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRNILLIGDGLLADYVHDQLCEQYSIIRQHTITEELPENIHLAL
                     VLHDGSPSTIHHDAELIFRSNHIPWLRGFTSFGEGIIGPYIHPLSSGCSHCSDGRRFIA
                     GFDQQEMWELQRKYAFKADNVTRRDVRATQNGMLQMCHLIRVETEKILTHNHSSLENEL
                     ILLNLQTLQCTRHSFLPDPLCPICSNLPDDTADAAELSLQPSLKVSTETYRCRSIHELN
                     TFLTRDYLDYRVGMLNGKMQHSLLPFADVIINMPLMFGNEGVAGRTHSFAVSEATAILE
                     GLERYCGMSPRGKKTNVHGSFHDLEEHALNPLTLGVHTNEHYNRDSFPFKPFDPDYEQN
                     WVWGYSLSQNRPLLVPESIAYYSLGHRDAFVYETSNGCAIGGSLEEAIFHGILEIVERD
                     AFLLTWYAELPLPRLDLSSANDTELQLMIQRLRMITGYELHAFNATMEHGIPSLWVIAK
                     NTRENGMNVVCAGGAHLDPIRALKSAIQEIAGMLLITDDELEHKREYYEKCLQDPYFVN
                     KMEDHSMLYGLKETEERLHFLLRENAPVQTFQEMNVSQSFDMDLTSDLHQLLNRLHQSE
                     LEVIVVDQTVPLIEKNGLHCVKVIIPGMLPMTFGHHLTRVTGLDRVYTVPMTLGYTDEP
                     LTNERLNPHPHPFP"
     gene            complement(13504..15423)
                     /locus_tag="GE376_RS06185"
                     /old_locus_tag="GE376_06320"
     CDS             complement(13504..15423)
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03693"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Heterocycloanthracin_C_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiopeptide_F_RRE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016513905.1"
                     /locus_tag="GE376_RS06185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_06320"
                     /product="putative thiazole-containing bacteriocin
                     maturation protein"
                     /protein_id="WP_001061546.1"
                     /sec_met_domain="TIGR03693 (E-value: 0.0, bitscore: 1219.0,
                     seeds: 2, tool: rule-based-clusters)"
                     /sec_met_domain="Heterocycloanthracin_C_RRE (E-value:
                     6.4e-55, bitscore: 181.5, seeds: 5, tool:
                     rule-based-clusters)"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 4.3e-11,
                     bitscore: 41.0, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNLPIHAKLKVNKDTFFLPDSNGGVYFRNNASSFRMDGAGIYDW
                     IEKLMPMFNGNYSLAEITDGLPLPYQNRVFEIGEILYENGFVRDTNQDEPHELNSTLLD
                     RYASQIEFLEADSHSGALKFETYRGANVLVLGSGDMLTSLVSSLLESGLPTFHYLVTDR
                     DETNYDRIHELIERAYEVDNTVLLQEIDTTIDRPLHEVFEPFDWILYVSQNGDIDGLKT
                     VHTICREAKKNFIPAICLSTLGIAGPVVTENRDECWESAWHRLHETTLQNENSSDSFSP
                     ITSAMLANVIVFELFKHVADDSHREKGSQFFLLNYETLEGTWHPFIKHPLATDESFTID
                     TIENLSEKLEHRSNQHTSTDVFQFFDSLTSKEAGIFHVWDEQDSYQLPLSQCYIQVANP
                     LSDGPAPLLPLMTCSGLTHNEARREAGLTGIETYVAEIIHRLIPEHNDIGIGAGETMTE
                     GFYRALQQHLNNKLYERQSHTLEELTTIDLTDIHDKHCRFYYDALSTIHETPTIAMSEE
                     ILSFPVVWIGINDRWYGASNINMTLALRNALQLALFHIQNEEIPYRANILYDSSIILYD
                     TDSFRVEIQPEEEIPNVQSLQLALQHLEEHNFYPFVFDLAIEPFLKENLDGVYGVLIAK
                     EDGL"
     aSDomain        complement(15124..15423)
                     /aSDomain="Heterocycloanthracin_C_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing C protein in a
                     heterocycloanthracin LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_GE376_RS06185_Heterocycloanthracin_C_
                     RRE.1"
                     /evalue="3.30E-57"
                     /identifier="RREFam011.1"
                     /label="GE376_RS06185"
                     /locus_tag="GE376_RS06185"
                     /protein_end="100"
                     /protein_start="0"
                     /score="181.5"
                     /tool="antismash"
                     /translation="MNNLPIHAKLKVNKDTFFLPDSNGGVYFRNNASSFRMDGAGIYDW
                     IEKLMPMFNGNYSLAEITDGLPLPYQNRVFEIGEILYENGFVRDTNQDEPHELNS"
     aSDomain        complement(15157..15393)
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_GE376_RS06185_Thiopeptide_F_RRE.1"
                     /evalue="2.20E-13"
                     /identifier="RREFam004.1"
                     /label="GE376_RS06185"
                     /locus_tag="GE376_RS06185"
                     /protein_end="89"
                     /protein_start="10"
                     /score="41.0"
                     /tool="antismash"
                     /translation="KVNKDTFFLPDSNGGVYFRNNASSFRMDGAGIYDWIEKLMPMFNG
                     NYSLAEITDGLPLPYQNRVFEIGEILYENGFVRD"
     gene            complement(15548..16807)
                     /gene="odhB"
                     /locus_tag="GE376_RS06190"
                     /old_locus_tag="GE376_06325"
     CDS             complement(15548..16807)
                     /EC_number="2.3.1.61"
                     /GO_component="GO:0045252 - oxoglutarate dehydrogenase
                     complex [Evidence IEA]"
                     /GO_function="GO:0004149 - dihydrolipoyllysine-residue
                     succinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="odhB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016716916.1"
                     /locus_tag="GE376_RS06190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_06325"
                     /product="2-oxoglutarate dehydrogenase complex
                     dihydrolipoyllysine-residue succinyltransferase"
                     /protein_id="WP_000569892.1"
                     /transl_table=11
                     /translation="MIEIKVPELAESITEGTISQWLINVGDKVEKGGSVVELETDKVNV
                     EIIAEDSGIVSKLLGEPGDTVEVGATIAILDANGAPVAVSTPAPAAEQPKQETAEAPKA
                     AAPNAEQTTGLQGLPNTNRPIASPAARKMARELGIDLNDVRSTDPLGRVRPHDVQAHAA
                     APKEAPAAPKSPAPAPVAKTEFEKPVERVKMSRRRQTIAKRLVEVQQTSAMLTTFNEVD
                     MSAIMELRKERKDAFEKKHDVRLGFMSFFTKAVVAALKQFPLLNAEIQGDELIIKKFYD
                     IGIAVAAPDGLVVPVVRDANQLNFAEIESEIRNLGMKARDNKLSLKELQGGTFTITNGG
                     VFGSLMSTPILNSPQVGILGMHKIQVRPVAIDAERMENRPMMYLALSYDHRIVDGKEAV
                     SFLVAVKDMLEDPKSLLLEG"
     gene            complement(16940..19807)
                     /gene="odhA"
                     /locus_tag="GE376_RS06195"
                     /old_locus_tag="GE376_06330"
     CDS             complement(16940..19807)
                     /EC_number="1.2.4.2"
                     /codon_start=1
                     /gene="odhA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000197121.1"
                     /locus_tag="GE376_RS06195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_06330"
                     /product="2-oxoglutarate dehydrogenase E1 component"
                     /protein_id="WP_098842166.1"
                     /transl_table=11
                     /translation="MTRKNTTTNPWAKFHGPNLGYVIEQYDLYVTGAGSVDPELQELFE
                     IFGAPSFQDDVVTGDNTATHFSPQNTGNIEKILKVVQLVDQIRSFGHTLAHINPMEDAA
                     NGQSLLEKAMNELSDADLKAIPAKTVWQDAPEGIHTALDVIHRLKDVYTKSLAYEFSHI
                     QDSEERAWLHQMVESNSLRQPLSNKKRTALLKRLTAVEGFEQFLHKTFVGQKRFSIEGV
                     DMLVPVLDEIVLEGAKNGVEDVMIGMAHRGRLSVLAHVLEKPYTHMFAEFKHAKIEGAV
                     ANAGWTGDVKYHLGREQVVSNEEVSTRVTLANNPSHLEFVNPVVEGFARAAQENRKKSG
                     LPEQDTSKSFVILVHGDAAFPGQGIVSETLNLSRLNAYQTGGTIHVIANNAVGFTTDSY
                     DSRSTKYSSDLAKGFDIPIVHVNADDPEACLAAANLAIQYRTLFKKDFLIDLIGYRRYG
                     HNEMDDPAVTQPQVYKKIKNHPTVRAIYADQLQAAGVLNADEIETITQFTQEQLKSDYA
                     QVPPADTSDATIHVKVPDVVAKGIQPIDTGVELDSLRAINEGLLSWPEGFNVYPKVKKI
                     LERRKDALEENGKIEWALAESLAFASILQEGTPIRLTGQDSQRGTFAHRHIVLHDTDTN
                     ETYSPLHRLPNINASFSVHNSPLSEAAVVGYEYGYNVFAPETLVMWEAQYGDFSNTAQA
                     LFDQYVSAGRAKWGQKSGLVLLLPHGYEGQGPEHSSARPERFLQLAAENNWTVANLTSA
                     AQYFHILRRQASILGTEAVRPLVLMTPKSLLRHPLTLSTASQLSEGRFQPALEQENLGT
                     KPNKVKRLVLSTGKMAIDLAAEIESGKHEYNLDEVHVVRIEQLYPFPAEKVQSIIKRFK
                     NLEEIIWVQEEPRNMGAWHYMAPILFELAGDKVKTGYIGRPDRSSPSGGDPFAHKAEQE
                     LIVAHALDVKYNFRQDKLEIEVFSN"
     misc_feature    complement(20221..20241)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 26.69"
                     /tool="antismash"
     gene            20632..20841
                     /locus_tag="GE376_RS06200"
                     /old_locus_tag="GE376_06335"
     CDS             20632..20841
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428510.1"
                     /locus_tag="GE376_RS06200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_06335"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000428506.1"
                     /transl_table=11
                     /translation="MENKMVEYRKKFGLSQEKLAEKLGVSRQTIISIEKGKYDPSLPLA
                     FEIAKTFQTTIEHVFIYEGKEEGE"
     gene            20844..21221
                     /locus_tag="GE376_RS06205"
                     /old_locus_tag="GE376_06340"
     CDS             20844..21221
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016101524.1"
                     /locus_tag="GE376_RS06205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_06340"
                     /product="hypothetical protein"
                     /protein_id="WP_050842906.1"
                     /transl_table=11
                     /translation="MNYSQKYFVIMGVIFLFMSGFMILTGIMTHSAPPAITYPLLGMMI
                     MSFCLSYLHPQFKEKDERMKLIRYKGMFFSFFALTAYYLLFSIGLNLKILTLSATELLN
                     ILMALTMSTVFISFVVLAKRY"
     gene            21250..21432
                     /locus_tag="GE376_RS06210"
                     /old_locus_tag="GE376_06345"
     CDS             21250..21432
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002086895.1"
                     /locus_tag="GE376_RS06210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_06345"
                     /product="DUF3976 domain-containing protein"
                     /protein_id="WP_001178303.1"
                     /transl_table=11
                     /translation="MQMMYAFGIGLVLFLAVFLFIRKDVQGGTLTKRGFYKMIGCLVVM
                     FIAIIVMIVLISRSL"
     gene            21579..21927
                     /locus_tag="GE376_RS06215"
                     /old_locus_tag="GE376_06350"
                     /pseudo=""
     CDS             21579..21927
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034134.1"
                     /locus_tag="GE376_RS06215"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_06350"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MFYLLTCLLLVASTAYYNM"
     gene            21956..22207
                     /locus_tag="GE376_RS06220"
                     /old_locus_tag="GE376_06355"
     CDS             21956..22207
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002126037.1"
                     /locus_tag="GE376_RS06220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_06355"
                     /product="hypothetical protein"
                     /protein_id="WP_140157268.1"
                     /transl_table=11
                     /translation="MSYPWVLRKTFFLCFILSPIGAACILMNRGAIQKRDFILYLLFAA
                     MNISLWLLLMIFDWSMWMVVGHYLFGAVVIVFSNMNKS"
     gene            22295..>22438
                     /locus_tag="GE376_RS06225"
                     /old_locus_tag="GE376_06360"
                     /pseudo=""
     CDS             22295..>22438
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014654109.1"
                     /locus_tag="GE376_RS06225"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="GE376_06360"
                     /product="WXG100 family type VII secretion target"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKVTPERLEQTAKTVNNIRHFLEYLHNDLYNQIKNIAIQWNGASR
                     EQF"
ORIGIN
        1 gaagaaatgg ttacaatatg cgacggagtt gtcgttggaa gtaagatcat tgagctttta
       61 gaaactgaaa agcgagaaga aatatgtgaa ttaatatatg caacaaaaca aaaagaagag
      121 gcgtagtctc ttctttttgt tttgcgtaat aaatgttaaa atatacagaa aatacatgta
      181 atttagaggg tgagaagaca tgctaagacg gaaattacta tatcttcttt taactgtacc
      241 actatacgct tggctcatta gcatgacgaa aatagagttg atggctctat ttttaggata
      301 tgtatttatc ttttccaact taaatcgcat tcaagaacag tctattttag aaatatgtct
      361 attttcgatt agtatagaat tatttagtat cgtttcgatt gtattattaa acgaattatt
      421 tctacggatt cattcattta cattaatgaa attttggaat attgcattgc aagcaatatg
      481 tacttacatt gtgtttgttg tgttgaaaaa aataatcgga cagcagacag tttttcagga
      541 taatagaaaa tgggagtgaa tgaaaagggg ccgtttggct ccttttttaa atctgtttta
      601 aaaacaattg aaaatcacaa catctgttat ataatagtta aaaattgtat tttaaacgaa
      661 atgagatgat aacatggcca tattgttggc acttatccca attatgatga ttttcatttg
      721 tttattttta tttaaacaaa cgtcattaag gtctgcgtta atttcttatg ctgtatgtgt
      781 tggaatcgtt ttactctcgc caacgtttca attagggata agtgaaactg ttcacgcaac
      841 gattaaaggt tggttaattt gttttattgt tgggtacgtt ttgtttttcg gtattttttt
      901 atttcacctc atgaacaaaa tgggatacat cgatcaagta gcgcgttttt tagaagaagt
      961 gacgcacgat cgtttattac aaatgctcct tatgtgtttt ggtatttgtc cgctaattga
     1021 atcagtaagt ggattcggaa ttggcttcat ggttgcagca cctatctttc tatcattagg
     1081 ttataaaccg tttcaagctg tactactttc atttattggt ttactagcta gttcatgggg
     1141 cgcaatggca actggtacga ttatcggttc gcagctaata aatatgcctc ttacaacact
     1201 tggtacaaat acagcgctat taagtattcc gatgtttgct tactttgtta ttctttcttt
     1261 atacgttgtt ggcggctggc aagcagttat agaaaagtgg aaagaaggag taggattctt
     1321 tctattattt tctctcggaa tctatctttc taatgcgtac gtaagtgttg aactagccgg
     1381 gatattaagt tctatcgtta cgattacatt tggttttctt atcattaaat taaaaggaaa
     1441 aagtgaacaa aatctaataa cagagcatgc ggctgcaacg gagagagaag tatccattat
     1501 aaaaattatt agcccttata tatttctaac agtttgtatt ttactttctc gcctggttcc
     1561 agcattacat gatttgttca gatcatatgc ggttcttgat ttgaaatcat actcttacaa
     1621 actagagtta ctatattcac caggattttg gctcggtatg acttgcttat ttactattat
     1681 tttcttccgc atcccgtcta atattattaa acaatcactc tcgcaaacga tcaaacaatg
     1741 gattcctttt gctattacta cgacaatgtt tatcgccatt tcagaattaa tgggtgcatc
     1801 aggcatgcat ttattactcg caaagatagc tggtgaaaca tttggaacct ttttcgtttt
     1861 ctttgctccg tttattggcg ctattggtgg atttttaaca ggtagtaacg caggatcaaa
     1921 tgcaatgttt ataaaactac aaatgcaaac cgcacaaaac gtagcactcc cgtggcaata
     1981 cgtcacaaca ctgcaaaaca ccgcatcatc agtagcgaca atcgcttgcc cgtcacggat
     2041 tacactaggt gcttacttat gtaatatccc ttaccgtgaa aatgaactgt taaagaagac
     2101 aacgttaatg atctttggtg cggttttgct tgtaatggta gaagttatcg tttggtatat
     2161 gttgagaaat taaaaatcct cctaacatag gaggattttt tttatgagtg gataatgatt
     2221 taaatatgaa tagcttctac taaatgaata ggagatgaaa tgtatgcccc taaaaaacta
     2281 cggtgtgtta aaaggtacag ttatacaatc aaagattgga aaagggaaaa cacctcatta
     2341 tcaagttcat ttacagggcg agactggagt agattatcgt attgctatta acgtaaagtc
     2401 gcaaagttat ccgtcagaag ttttatattt tgcgagtaac aatattaggt cagaggcgat
     2461 tcatatttta ccgacattac catttggttt tacggaagta aaaaacaatg aaccgaaagt
     2521 agctttagat tatgtaagag gaaatctatt tgactcaaaa caaatgattc ctttgcctcc
     2581 cgaaaaagca ggagcagata atgatttaaa cgaaaaaata gaacgttata taaagcgagc
     2641 gatggaagaa aaagcaatta tttatgcgtt tggcgaaaga tggggaccag aagaaaacac
     2701 accagattcc tattttcatt tcaaaccagg aaacggtata catgatattc acatgaatca
     2761 agggaatgta gaaaaatggc aaggtgatga tggcatatgg caagatggag gaatacttat
     2821 tcactttgaa aaggaagaag aatggatcgg tatctttctt gccttccaat cacagtcatg
     2881 gtgtaccgat gaagaggggc atgctcgtgt gcctgttgag cattgtgatt ataaggggaa
     2941 taattaataa gaagagggcg ttcaaaaaga acgccctctt cttattttat aaaacgaaaa
     3001 actaacgagt gtagaaagac aagagaacag cagtgccaca ctagaaaacg caatgagata
     3061 catattatat ttcataacct gtccaattag ctgattactg tcgtattgaa acagtcctgc
     3121 tattatgttg aataaaaata acacgataaa catgacgaca acaccgtcta ttgatccttt
     3181 aatgtctggt ttacttaaag cgatatgtgc ggaaatgcaa atggcgataa ataaaaataa
     3241 ccaaaaggaa ggattcaata aattgccgat tgtaaataag cttttcaata atacaaacgt
     3301 cgacaagagc atgttttgaa tcatttctac attaatagaa gtagaagcaa tcgttttttc
     3361 gagagttgta ttaaataaaa aatatgattc tggtacgaaa tagcgcatta aaaggattaa
     3421 tgcagtaata ccagaaataa taggcccaat gccgataaag aaattcccaa ttcgttgata
     3481 cacacttttt tgattgtatt gatgttgtat ataacctaaa gccccttgac ttgtatctgt
     3541 tgggaagaac tgagtcgcca caattttatg acggaacagt acgcacataa tggcatgtcc
     3601 aagttcgtga atcggaacac cgatccaagc cgttaatagg aatccttttc ttccaaaagc
     3661 tctcgaccaa tacatgcgtg tgagagattc taaatagcct aatagaaatc caattacaat
     3721 gataacgcca attaaagata ataattggat tacgcttgta aggagtattt gaaaaattga
     3781 gtttaccaat tccattttct ttcatccaat ctgttaaaaa tattatttat tctgtttcat
     3841 aatagcattt tttttcaaga ttgctagcac atatattttc tttcggaaga aggatttcag
     3901 aatctttttc ttgtagtcat gttttatgta caaattcata tattgaactt gtaacaccct
     3961 ataaggtata tgcttaagga gggataagag aatgaaatgt ccgtcatgtc atacaaaaaa
     4021 tgcagtagag gcaaagtttt gcgggaattg tggacattcg ttaacggaag aagtagtggc
     4081 aagtagtggc caagaagaag ggccggaaca agcacgtgcg gcacaagcaa aggaagctcg
     4141 gccaaatgaa acggtagagc aagcgaagcg gtttgcgagc ggctattttc aattttttaa
     4201 acatgcatta caagcaccga cagcgattat gaaaagcggc gctattgaag tgcgaaatgg
     4261 aattgtaagt cttgttctta tttgtttttt aggagcatgt attttttata gaatgatgag
     4321 tgcagcatca gcagttacga gaacatttgc accagatata tctactccca cgttttttgg
     4381 agaatctata acggtctttt tctttttatt aattttaact ttatttgtcg gatttattat
     4441 ttttgtaagt ggtaagatga tgaaatcatc tttttcgttt cttgaagtat ttggtatatg
     4501 gggaacgata gcaacgccgg ctattgtcat attagttctt tcttttcttt ttagtttttt
     4561 attaatcttt ttcttaccga tattattatc ggtagttgca acttatatag ggattagtat
     4621 aactgtagcc gtattaaaac tagacaatgg cggattagat ctcgtttaca cacttattat
     4681 tgcaaatgtt ttaattggaa ttgcaacgtt cattgtactt tggtcttaca ttagcacgat
     4741 aattcaagcc ttaacacagg gaataactgg cttctaatga aaaggtggtt gactgaatga
     4801 atgtatgtac aaagtgcgga gttcagtttg aagatggtgt gcaattttgt caaaactgcg
     4861 ggatgaagag gggaagtcct gtagtaaaga agaacatgag cagtggtaca aaagttggca
     4921 ttacactgtt agcactattt gttatagcga ttattggatt gtatttgtac ggatcatcgt
     4981 attatacgca ggtggcacaa gtagaccgga tgattacgat tttacaagag cgggacggag
     5041 agaaattagc tgagatcgtt acggcagatg atccatcggt tatgataacg agagagaatt
     5101 taacgcctct attttcatat ataaaagaaa atccagctta cgtaaatgaa ttaaaagaat
     5161 atttgagaca aggtgaaaaa caacgggacg gaatagaaag agctgatttt tcattaacga
     5221 aagacggaaa gtatttcttt atatttgatc ggtataaatt gaaagcgaag acatactata
     5281 caactttgct tacaaatgaa aaaggcgtag cgttaaaaat gaacggaaaa gaaattgata
     5341 agacagatga caaaaagttt gagaagcaat atgggccatt tcttccggga aatcaagtgt
     5401 ttcaatcaga atataaaaat gactatgtaa aactatctcg tgaggaaaag gttgtactta
     5461 tgaaacaaag ccaaaataac gtaacgatag atttaacgtt gcaaggtcaa tatattacag
     5521 ttcaaacgaa cgcgcctggt gcaacattgt acgtaaatca aaaaccggtt acagcgctcg
     5581 caggagaagc aattacatgg gggcctgtag cgactgatgg aagcgcgaaa atttatttag
     5641 aacgaaatgg agaaaatgga cgggaaacga caaaattaga gacggtaacg gcactttcgt
     5701 cttataatct tccattccaa acgaaaagtg cagaaaaaac agttgtttat aatgttactc
     5761 caacgcccgc gactgggtat gtatataatg gtttcatctt tcctgatagt gatattcgaa
     5821 aattaacgag cacagattta acctatttat cgaaagaaca gttgaaaatt gctagaaatg
     5881 aaatatatgc aaggcatgga catatttttc aaacgaaaga tatgcaagcg tattttgcaa
     5941 aacagtcttg gtatagagaa aatccttact ttacaggaac gttaacagat atcgaaactt
     6001 ataatattga actgattaaa tcaagagaat agaacacatg aaaaaaggta cggtgcataa
     6061 ctgtaccttt tttatggttt ttttttatct gaaccaggat cccttgagaa aaagatatga
     6121 aagaggaatg tgactttact tgctcctcct gatgtacttg cttgcacgtc agataatgcg
     6181 ttagatgtta aaacaccttc agaatgaggg ggtacgacta ttttgagagt atcatctgat
     6241 tctgatgatg cagtaactgt tattgtatca tcagataagt ttaaaatttt tacagtaccg
     6301 attggtaaga tggacttgcc agcgtgtgat gctgaagcaa agcgagagcc tttccaaatc
     6361 gtttgtggaa aagtttcatc attagataac caagcacgag cactataaat ggttgcgtta
     6421 atagaaaatt cttgatcaag cgacaaggcg ggttttggtt ctttcggttc ctctggaaac
     6481 tgagcgagaa gaccagcgca catgtatatt tcacctactt tcaattggtt actgttatag
     6541 catattaaac atgttgttta taagacacga cagttaccta ttcatacata agtttgtgca
     6601 ccaaatttga agatgaaatt ctctttcttt acaatggaag taggtgttat ttctataaaa
     6661 tatggaaaac gtaaagagta tgtaaaaaag aaggagtggt aaagtgaact atgtcattat
     6721 tggcggagat gcagctggta tgagtgcagc tatgcaaatt gttagaaacg atgaaagtgc
     6781 aaatgttgta actttagaaa aaggtgaaat ttattcatac gctcagtgtg gattaccgta
     6841 tgtcattagt ggtgctatcg cttcaactga aaagttaatc gcgcgcaacg taaagacgtt
     6901 tcgtgagaaa tatggaattg atgcgaaagt gcgtcatgaa gtaacgaaag tagatacgga
     6961 aaagaaaatg gtgtacgcag agcatacgaa gacgaaggat gtctttgaat ttccatatga
     7021 tcgattatta attgcgactg gagtgcgtcc tgttatgcca gaatgggaag gacgggaatt
     7081 acaaggcgtt catcttttaa aaacaattcc tgatgctgag cgcatattaa aaacgttaga
     7141 aacgaataaa gttgaagatg taacgattat tggcggtggt gcaatcggac tagagatggc
     7201 agaaacattc gtcgaacttg gtaagaaagt aagaatgatt gagcgaaatg atcatatcgg
     7261 tacgatttat gatgcagata tggctgaata tatacataaa gaagcagata aacacaatat
     7321 tgaaatttta acgaatgaaa atgtaaaagc atttaaagga aatgaacgag tagaagcaat
     7381 cgaaacggat aaaggtacgt ataaagcaga tcttgtttta gtgtcggttg gagtgaagcc
     7441 aaatactgat tttcttgaag ggacaaatat acgtaagaat cataaaggag caatcgaagt
     7501 aaatgcatat atgcaaacga atgtgcaaga cgtatatgca gccggtgatt gcgcaacaca
     7561 ttaccacgtt ataaaggaaa ttcatgatca tatcccgctc ggaacgacag ccaataagca
     7621 agggcgactt gctggactga atatgctgga taaacgaaga gcttttaaag gtacgttagg
     7681 cacaggcatt attaaattta tggatttgac gctcgcaaga acagggttaa atgaaaaaga
     7741 agcaaaaggg ctacacattc cgtataaaac ggtcaaagta gattctacaa atatggcggg
     7801 ctattatcca aatgcaaaac cactttactt gaaattacta tatcgctccg atacgaaaca
     7861 attattgggc gggcaagtaa ttggagaaga aggcgtagat aaacgtattg atgtgattgc
     7921 gatggcactt ttcaataaaa tgagcattca tgatttagaa gatgtcgatt taagttatgc
     7981 accaccatat aacagcgttt gggatccaat tcagcaagcg gcaaggagag cagaatagca
     8041 ctttttaaag tgctattttt ttgttaaagg ggaattatca tttttgtcga atgaagagga
     8101 tcgggaaata gttacatatg tgaaagggga gttttttatg attgtagcac ttcaaaaagt
     8161 tcaagaatca gaaaaagaaa tattacgtaa tttgtatgca ttatatcttc atgacctttc
     8221 taagttcact atgaatataa ctatcggagc gaacggtttt tttgaatacg aagatttaca
     8281 catgttttgg aaacatgacg gaatcactcc gtattttata aagattgatc atagtattgt
     8341 agggttctta ttactactgg aacgtccgtt tttgaagaag gaaaatgatt ttggtattaa
     8401 tgatattttc atattgaatc aatataaagg aaaaggaatc ggtaaacaag ttgttgagaa
     8461 tttactagaa gagaaacgag gacaatattt cgttatcgaa cttctaaaaa atgtaccagc
     8521 agtttcgttt tggaagaaag tatataaaga actgaacatt gaatttgatg agagagagca
     8581 gctaattgat gctgaagaat gcctcgttca aacgtttaaa atataatgaa attggtgctc
     8641 cttttatatt actttgaaat ttaactttat cccgctattt gcggacagta agacccccac
     8701 ctcaaaatcc agtgaaagca aagaagttag gtgggggatc aagaaaaacc ccactgatta
     8761 aagtttcact ttattttgaa tataccgttc ccccttgaaa acatattact aatcgcttat
     8821 attttcatat agtatttatt ttttaaacga agcaatgaac gaaccagggg gcgcagtatg
     8881 gcaattaata tgaaaacaat cgaagaatgg attgttgaat caaatgcaag acatgaagaa
     8941 gactttggac acgttgtaga agaaatgaaa gaagtatgtg tcggacttga taacgcgaca
     9001 ttaatttata cgaaaaatgt attttgtttc ggtaaaaaag tagaagtatt tttcttcttc
     9061 caagaccatg tcgtgattgg acaagaaaaa gacgaatata ttgagattga aaaattaaag
     9121 tatgatgaca ttataaataa taatttaaaa acaaatgaca aaaatacaac gttagaatta
     9181 aagtttgcta acggacaatc tattaattta gatagtttaa atgataacta cggtacgaaa
     9241 aattggttat ttgctagaca aattaagagt atttttaagt taatttagta aaaagcaggc
     9301 ccataaaggt ctgctttttt acttatttcc tattacacaa aggcaccctt tttcttcata
     9361 acattgcact tttgtaaatc ctgtcttata aaataggttt attaattctt catttgtttt
     9421 aaatttctcc atatggtatt gaattttgaa agtttcagcc actaataaaa aggagccgtc
     9481 tggttttaag acgcgaaata cttcttttat atcttgttca atatcaggcc aaaaataatg
     9541 agtttgaaag gcggtaatga gatcgaagaa gttcgtatgc tgtggaatag aagaaacgct
     9601 tgcttgttga acaattactt tttgtttttg aacatctttt gcatttgtct gtatagaatt
     9661 tttcacagct tgatcggagt aatcaatccc atatattccc ccaagtggag ttcgttttga
     9721 aagagtgtgt atggttttgc ctccaccaca gccgatgtct aatacgactg catctgtctt
     9781 tatatgtact ttctgtaatg cccaatttat taatctcgta tgtgcagcgt tcataataca
     9841 aagcatggag gaaccaattg ttccgctagg cttttttgct tgctgaatta atcgttgtaa
     9901 aatgctcaag tcaaactctc cttttatgta agaatatata ctcatttcgc tttttataaa
     9961 ttaaatcctt taaaaaagca cgccgataga cggcgtgctt ttaattatgc aaagcccctt
    10021 ttaaccaatt ccgcgcccga tatgccccaa ctggaacttg aataagagac gtttcattcc
    10081 cagcatcaat tccgtacaat tgatcacatg aatttgtatc aaaacttagt aacggatgcc
    10141 cgcccatccc catagcagtt gcagcaaaaa cgagtttatg aacgagtata ccagcttcca
    10201 tttgatgaat acggtatcct ctatagccta atgcacgtgt atagtaatct ttctttccaa
    10261 ctacatgtag gcaaagtggt acttgaaaaa ggtttacgtt atccatcgtc atactagact
    10321 gaaggggata acgaaggtct ccataacgaa tgggttgtat ggaatgtgtt ttactgttat
    10381 aagcgtaagc cccgttttta atatttttca cgttataaaa acatccatat aaggagacgc
    10441 gtgcattttc atttatatac ttgccatcaa ggtcgttgta atagaggaag gagaggctcg
    10501 cttcttgtag taaagtagcg agctcagctg catcccattt cgttaaaata aagtccgcat
    10561 caggagaata tcgtttttta caaagttgta ggaaatcata cgataaccgt tctactttcg
    10621 gtagctgtac agcgtacgta ttatgttgat agtgctcttc atgatgtagt gtttggaagt
    10681 gttctgtcga ttcaatcata gaagcttcat ttatttttgt tatcatcgga tgttcattta
    10741 catgttttga gcgaacgaaa tgttcatgtg ctaacggcgg aatttgttgc aacaactcat
    10801 gagaagtaac tgttttattt tcacggtaat cattgtgaaa ccaattagtt tctgattctg
    10861 tacttaaagg aataacggca tacacacttt cttcaccttc tgacaatccg agtaaatggt
    10921 tcagtgcacg gtctagaaac tgaaagtata cgccgttcgt ataaccgaac tgttttgcac
    10981 attctagtaa ttgtccaatg agaactccgc tatctaatcc ttgaaggcga tatgaaaaat
    11041 tattgtattt aaagaaattt ttccaaaaca tagtggatac gaatgcagca ccgaaacaat
    11101 catgtatatt acagcgatta ccgagtgcgt ctgctaaata agaatcgaaa tttccttcgc
    11161 gaagtaaaat aagtcggtga tgtgcgacgt cataatggta aatgccgtct ggataatcgt
    11221 caatttttaa atagatatac aattcattcg gatataaagc gccgcctgaa ggaatggatc
    11281 tgcgtaatac atttctctcg ctatttagct gacataattg tgttacacca aatgaatacc
    11341 aaaggtagtg accaatctca tctaaagtag gtgtagtaga agagttcggc aaagataacg
    11401 ggatttctaa ggagagcggg atggtaggta catttcgata taatttataa ggaagcggtg
    11461 cgtctttcca gtccacctca tgattcggca taatttcatc aatagagaaa tggagatgat
    11521 gtaaaaaagt atctagctgc atgaaatccc tcctttacta tggaaacgga tgtggatgtg
    11581 gatttaacct ttcattcgtt aaaggttcgt ctgtatatcc aagtgtcatt ggtacagtat
    11641 atacccggtc cagtcctgta acccgagtaa gatggtgacc gaacgtcatc ggtagcatgc
    11701 ctggaataat gacttttaca cagtgtagtc cgttcttttc tataaggggg acggtttgat
    11761 ctacaacgat tacttcaagt tctgattgat gcaaacgatt taaaagttgg tgaagatcgg
    11821 atgttaaatc catatcaaat gattgtgata cattcatttc ttggaacgtt tgtaccggtg
    11881 cattttctcg taaaaggaag tgaagacgtt cttccgtttc tttcaatccg tacagcatac
    11941 tatggtcttc cattttatta acgaaataag gatcttgtaa gcatttttcg tagtactctc
    12001 ttttgtgctc gagctcatcg tctgttataa gtaacatgcc tgctatttct tgaatggcac
    12061 tttttaaagc tcgaatagga tctaaatgag cgcctccagc acaaacaacg ttcattccat
    12121 tttcacgcgt attttttgca attacccata agctcgggat gccgtgttcc atcgtcgcgt
    12181 taaaagcgtg taattcatac ccggtaatca tacgtaaccg ctggatcatt aattgtaatt
    12241 ccgtatcatt tgctgaacta agatcaaggc ggggaagagg taattcggca taccaagtga
    12301 gtaagaaggc atcacgctct acaatttcta aaataccgtg aaaaattgct tcttctaaac
    12361 taccaccaat tgcacatcca tttgatgttt catacacgaa agcatctcga tgaccgaggc
    12421 tgtaataagc aattgattca ggaactaaaa gcggtctgtt ttgtgataaa gaatatcccc
    12481 atacccagtt ttgctcataa tcaggatcaa acggcttaaa tggaaaacta tcgcgattgt
    12541 aatgttcatt ggtatgtaca ccgagtgtga ggggattcag tgcatgttcc tctaaatcat
    12601 gaaaactacc atgcacattt gtctttttcc cacgaggcga cataccgcaa tatcgttcta
    12661 aaccttctaa aatagcagtt gcttcactca ctgcaaatga atgagttcgt cccgcaacac
    12721 cttcatttcc gaacattaat ggcatgttta taatgacatc agcaaatggt aataaagaat
    12781 gctgcatttt gccgtttaac ataccgaccc gataatctaa atagtctctc gttaaaaatg
    12841 tgtttaactc atgaatggaa cgacagcgat acgtttcagt acttactttt aagctcggtt
    12901 gtaaagaaag ttccgccgca tccgcagtat catcaggtaa attactacat ataggacaga
    12961 gaggatctgg aagaaaagaa tgccgcgtac attgtaatgt ttgtaagttg agtaaaataa
    13021 gttcattttc taaagaagaa tggttatgag ttaatatttt ctctgtttct acgcgaataa
    13081 gatggcacat ttgtaacatt ccattttggg tggcgcgtac atcacgcctc gttacattgt
    13141 cggctttaaa ggcgtatttc cgctgtagtt cccacatttc ttgttgatcg aagccagcga
    13201 taaatcggcg tccatcagaa caatgagaac agccagatga aagaggatga atgtaaggac
    13261 cgataatacc ttcgccaaat gaagtgaaac cgcgaagcca cggaatatga tttgagcgaa
    13321 aaataagttc agcatcatga tgaatagtag aaggagatcc gtcatgtaat acgagagcga
    13381 ggtgaatatt ttcagggagt tcttctgtaa tggtatgttg gcgaatgatg gaatattgtt
    13441 cgcataattg atcatgtaca tagtctgcaa gtaggccatc tcctataagc aatatatttc
    13501 gagtcataga ccatcctcct ttgcaattaa taccccatac acaccgtcta agttttcttt
    13561 caaaaatggt tcgattgcta aatcaaacac gaaaggataa aaattatgtt cttctaaatg
    13621 ctgtaaggca agctgtaaag attgcacatt tggaatttct tcttctggtt gtatttccac
    13681 tctaaaagaa tcagtgtcat ataaaataat agatgagtca tacaaaatat tagctctgta
    13741 aggaatctct tcattttgaa tgtgaaagag tgccagttgt agtgcgtttc gtaacgctaa
    13801 cgtcatattt atattagatg caccgtacca tctatcattt ataccaatcc aaacgacagg
    13861 aaaactaaga atctcttcac tcattgctat tgtaggtgtt tcatggattg tagagagagc
    13921 atcgtaataa aatctacaat gcttatcgtg aatgtcagtt aaatcaattg ttgtaagttc
    13981 ttctagcgta tgtgactgcc gttcatacag tttattgttt aaatgttgtt gtagtgcgcg
    14041 gtaaaaacct tctgtcatcg tttctccagc accgataccg atatcgttat gttcaggaat
    14101 aaggcggtga atgatttctg ctacatatgt ttcaattcct gttaaaccag cttctcggcg
    14161 tgcctcatta tgggtcaatc cactgcaagt cataagaggc aggaggggag ctgggccatc
    14221 tgatagtgga ttggctactt gaatatagca ttgtgataac ggtaattgat atgaatcttg
    14281 ttcatcccat acatggaata taccggcttc tttagaagtt aatgaatcga aaaattggaa
    14341 tacatcagtt gaagtatgtt ggttagaccg atgctcaagt ttttcagaaa gattctctat
    14401 cgtatcaatt gtaaaacttt catcagttgc aagagggtgt tttataaaag gatgccacgt
    14461 tccttcgagt gtttcatagt ttaataaaaa gaattgtgat cctttttccc gatgtgaatc
    14521 atccgcgaca tgcttaaata attcaaaaac gattacattt gctaacattg cagatgtaat
    14581 gggtgagaag gaatcagatg aattttcatt ttgcaaagtc gtttcatgta gacgatgcca
    14641 tgcagattcc cagcattcat cacgattttc cgttacgaca ggtccagcta taccgagtgt
    14701 tgataaacaa atagctggta tgaaattctt tttcgcttct ctacaaatag tgtgaactgt
    14761 ctttaaaccg tcaatgtctc cattttgaga aacatataaa atccaatcaa aaggttcgaa
    14821 tacttcatgc aaaggacggt caattgtagt atcgatttct tgaaggagta cagtgttatc
    14881 aacttcatat gcacgttcta ttagctcatg tattctgtca tagtttgttt catcccgatc
    14941 tgtaacgagg taatgaaatg taggtaaacc agattctaat aaagaagaaa ctaaggaagt
    15001 aagcatatcc ccagaaccaa gtacaaggac atttgcccca cggtacgttt cgaattttaa
    15061 agcacccgaa tgagaatcag cttctaaaaa ttcaatttgt gaagcatatc tgtcgagtaa
    15121 tgtactgttt aattcatgag gttcatcttg atttgtatcg cgaacgaaac cattttcata
    15181 taaaatctct ccaatttcaa atacgcgatt ttgatagggg agagggagac catcggttat
    15241 ttctgctaaa gaataattcc cgttaaacat tggcattagt ttttcaatcc agtcataaat
    15301 tccagcaccg tccatgcgaa atgaactggc gttatttcga aaatagacac ccccgtttga
    15361 gtcggggagg aagaaagtat ccttatttac tttaagtttt gcatgaattg gaaggttatt
    15421 cattttaatc ctccttacgt ttaggcatac attattactt tatgtcatga aatttgtccc
    15481 gtatgaacaa aataaaaaaa ggctgtagaa tgattcattc tacagccttt aataggttaa
    15541 aaatctatca accttctaat aataatgatt ttggatcttc aagcatatct ttaacagcaa
    15601 caaggaagct aactgcttct ttaccatcaa caatacggtg atcgtaagat agtgcaaggt
    15661 acatcatcgg acggttttcc atacgttctg catcaattgc aactgggcgt acttgaattt
    15721 tatgcattcc taaaatacct acttgtgggc tatttaggat tggtgttgac attagagaac
    15781 cgaatacacc accgtttgta attgtaaatg taccaccttg tagttctttt aatgaaagtt
    15841 tgttatcgcg tgctttcata cctaaattac gaatttcact ttcgatttca gcgaagttta
    15901 attgattagc atcgcgtaca actggaacaa ctaatccatc tggagctgct actgcaatac
    15961 cgatatcata gaattttttg atgataagct cgtcaccttg aatttcagca tttaataatg
    16021 ggaattgttt taatgctgca acaactgctt ttgtgaagaa tgacatgaag ccaagacgta
    16081 catcatgttt tttctcgaaa gcatctttgc gttctttacg taattccatg atcgcactca
    16141 tatcaacttc gttaaatgtt gttaacattg cagatgtttg ttgaacttct acaagacgtt
    16201 ttgcaattgt ttgacggcgg cgggacattt tcacacgctc aactggtttt tcgaattcag
    16261 tttttgcaac tggagcagga gctggactct ttggagcagc tggtgcttct tttggtgctg
    16321 cagcatgagc ttgtacatca tgtggtctca cgcgtccaag tggatctgtg ctacgtacgt
    16381 cgtttaagtc gattcctaat tcacgagcca tttttctagc agctggtgat gcaataggac
    16441 ggttcgtatt tggtaagcct tgtagacccg tagtttgttc agcatttgga gctgcagctt
    16501 tcggtgcttc agctgtttct tgttttggtt gctcagcagc tggagcaggt gtacttactg
    16561 caactggtgc tccattagca tctaaaattg cgatagttgc gccaacttca actgtatccc
    16621 caggttcgcc tagtaacttc gatacaatac ctgaatcttc tgcaatgatt tctacattga
    16681 ctttatcagt ttcaagctca acaacgctgc cacctttctc aactttgtcg cctacgttga
    16741 taagccattg tgaaatagtt ccttcggtaa tagattctgc aagctcaggt actttaattt
    16801 cgatcatttt aaatgtcctc cccttatttg cctaacggtg tgttttttct tcttttgtct
    16861 tcggtaatct ccatttgtta gcctgatccc gggcagaata tctgcccggg atcaagctag
    16921 aaaccgtcat tgttactttt taattgctga aaacttcaat ttctagttta tcttgacgga
    16981 agttatactt cacatctaaa gcgtgtgcaa caattagttc ttgctcagct ttgtgagcga
    17041 atggatcgcc gccagatggg ctagagcgat ctgggcgtcc aatgtaaccc gttttcactt
    17101 tatctccagc tagttcgaac agaattggag ccatgtaatg ccatgcgccc atattacgag
    17161 gttcttcttg aacccaaata atttcttcta agtttttaaa gcgtttaata atagattgaa
    17221 ctttctcagc agggaatggg tacaactgct caatgcgaac gacatgaacc tcatctaagt
    17281 tgtactcatg tttaccagac tcaatttctg ctgctaagtc aatcgccatt ttacctgtac
    17341 ttaaaacaag acgttttact ttgtttggtt ttgtgccaag gttttcttgt tctaaagcag
    17401 gttggaaacg tccttcgctt aactgactag cagttgaaag cgtaagtggg tgacgtaata
    17461 aactctttgg cgtcattagt actaatggtc gaacagcttc ggttcctaag atagatgctt
    17521 gacgacgtaa aatatggaag tattgtgccg cgctcgttaa gtttgcaact gtccagttgt
    17581 tctcagcagc taactgtaag aaacgttcag gacgtgcact agagtgctct ggtccttgac
    17641 cttcataacc gtgtggtaat agaagaacta aaccagattt ttgaccccat tttgctcttc
    17701 cagctgaaac atattgatca aataatgctt gcgcagtatt tgagaagtca ccatattgcg
    17761 cttcccacat aacaagagtt tctggagcga atacgttata accatactcg taaccaacaa
    17821 cagcagcttc tgataacgga ctgttatgaa cagagaagga tgcattaatg tttggtaagc
    17881 ggtgtaatgg tgaatatgtt tcatttgtat cagtatcgtg taatacgata tgacggtgcg
    17941 cgaatgtacc acgctgtgaa tcttgaccag ttaagcgaat tggcgtacct tcttgtaaaa
    18001 tagaagcgaa tgctaatgac tcagcaagtg cccattcaat tttaccgttc tcttcaagag
    18061 catctttacg gcgctcaaga attttcttca ctttcggata tacgttaaag ccttctggcc
    18121 aagataatag accttcatta attgcacgaa gtgagtcaag ctcaacacca gtatcaattg
    18181 gctgaatacc ttttgcaaca acatctggca ctttaacgtg aattgttgca tcgctcgtat
    18241 cagctggtgg tacttgtgca tagtcagatt ttaattgctc ttgtgtaaac tgtgtaattg
    18301 tttcaatttc atctgcattt agaacaccag cagcttgtaa ttgatctgca taaattgctc
    18361 ttacagttgg gtgattttta atctttttgt acacttgtgg ttgtgtaact gctgggtcat
    18421 ccatttcgtt atgaccatag cgacggtaac caattaaatc gattaagaaa tcttttttga
    18481 acaatgtacg atattgaatt gcaaggtttg cagcagcaag acaagcttct ggatcatcag
    18541 cgttcacgtg aacaatcgga atatcgaaac cttttgcaag gtcacttgaa tatttcgtag
    18601 aacgagaatc atagctgtca gttgtaaaac caactgcatt gtttgcgata acatgaatcg
    18661 ttccgcctgt ttggtacgca ttcaatctgc ttaagttcaa cgtttcagat acaatacctt
    18721 gaccagggaa tgcagcatca ccatgaacta aaattacgaa tgattttgaa gtatcttgtt
    18781 ctggaagacc agatttttta cgattctctt gagctgcacg tgcgaaacct tctactacag
    18841 gattcacgaa ctcaagatga ctcgggttat ttgctaaagt aacgcgagtg ctaacttctt
    18901 cattactaac gacttgttct ctacctaagt ggtatttcac gtcgccagtc cagccagcat
    18961 tggctactgc gccttctatt tttgcatgtt tgaattcagc aaacatgtga gtatatggtt
    19021 tttctaatac gtgagcaagt acgcttaggc gaccgcggtg agccatacca atcatgacat
    19081 cctctacgcc gttcttagca ccttctagaa caatttcatc taaaacaggt acaagcatat
    19141 caacgccctc gatagagaaa cgtttttgcc caacgaatgt tttatgcaag aattgctcga
    19201 aaccttcaac agctgttaaa cgttttaaaa gagcagttcg ttttttattt gatagtggtt
    19261 gacgcaatga atttgattcc accatttgat gcaaccacgc gcgttcttca ctatcttgta
    19321 tatgagaaaa ttcataagct aaagattttg tataaacgtc ttttaatcta tgaattacat
    19381 caagtgcagt gtgaatacct tctggtgcat cttgccatac tgttttcgct ggaatcgctt
    19441 tcaagtctgc atcgctcagt tcgttcattg ctttctcaag aagagattgt ccgtttgcag
    19501 catcttccat cgggttgatg tgagccaacg tatgcccgaa agaacgaatc tggtcaacaa
    19561 gttgaacgac cttaagaatt ttttcaatgt tacctgtgtt ttgaggagaa aaatgtgttg
    19621 ctgtgttgtc ccctgttacg acatcatctt gaaacgaagg agctccaaaa atttcaaaaa
    19681 gctcttgtaa ttccggatca acagaacctg ctccagttac gtaaagatca tactgttcaa
    19741 taacataacc aaggttcgga ccgtggaact tggcccaagg gtttgtcgtt gtattcttcc
    19801 tcgtcatttg tttaaacctc ccaatgcata taatcctttt tccatacaaa ggtgcatttt
    19861 gctctttttc aataagtaat gaatcaataa tcaatgtaaa tgttttcttt actcttatgt
    19921 tattacaata atttacataa taccaaacac tattacttat ctgttttgta aaaaaacatt
    19981 cacaataact tatcacccaa gttaatcttt cactttataa agtaatttta cagaaaaatg
    20041 gggtggatat atttggtata cctacattaa aaactagaat tgttacatgt aaatataagt
    20101 ataatcgttg gaatgttttg ataaaagttg attagaatta tgtatattga aataataagc
    20161 gctttcatag atattataca acaatataac ggaatatagt ataaaaaata aaaaattatg
    20221 aatttagcgt aaactttatt tcgatagtgt taactatcga aaggaaaatg aaggatttcc
    20281 acaaaaaaag tggctaaaca taaaaattgc ttcataaccc gttagtttct ataaatatgc
    20341 caaaaaacac cgtaaaacca ataacgcatt tcatctaata aagaagagaa tgaaatattt
    20401 taaaaggata aaacaaatat gaagatatta aattttaaaa aaggtgagga ggaaatatag
    20461 taacgattac atacagtgtt ccatgtttta ttacaaaata gacgtgctca aatcgaacaa
    20521 gtttcttcta tataaataga gtaaaaaatg attggaataa atgtaaagga accttgacgt
    20581 aaagtttgct ttacatatat actcgatata tggaaggagg gagaaatttc cttggaaaat
    20641 aaaatggtcg aataccgaaa aaaatttgga ctatctcaag aaaagttggc tgagaaactt
    20701 ggagtttcca gacaaaccat catttcaatt gaaaagggga aatacgatcc atcacttccg
    20761 ctagcatttg aaatagcaaa aacatttcaa acaacgatag aacatgtatt tatttatgaa
    20821 ggaaaagaag agggggaata gggatgaatt attcacaaaa gtactttgta attatgggtg
    20881 ttatttttct atttatgagt ggatttatga tattaacagg tataatgacg cattctgcac
    20941 cgccagctat aacgtatcca ttgcttggga tgatgattat gagtttctgt ctaagctact
    21001 tacacccgca atttaaagaa aaagatgagc gaatgaaact cattcgttat aaaggaatgt
    21061 tcttcagttt ttttgcgtta acggcatatt atcttctttt ctctatcggc ttaaacttaa
    21121 aaatacttac actatctgct actgaattat tgaatatact tatggcactt acaatgagta
    21181 ccgtctttat ctcatttgtt gttttggcaa aaagatatta agatggaaga gagaaaggaa
    21241 gattaatata tgcaaatgat gtatgctttt ggcattgggc ttgtattatt tttagctgta
    21301 ttcttattta ttcgtaaaga cgttcaaggc gggacgttaa cgaaacgagg attttataaa
    21361 atgatcggct gtttagttgt tatgtttatt gcgattattg taatgattgt tttaataagt
    21421 cggtcactat agaatgtaaa aaaggaacct tacttcggta aggtttttct ttattgttca
    21481 acctgaaaat taccgctaaa tccatttatt ataaataact tatattatat aatccaatga
    21541 aatgatagat aaggagtgta gtatatgaat aaaaaactat cttctattta ttaacttgtc
    21601 tactacttgt agctagtact gcttattata atatgtaaca aacgagaaca agtgccacct
    21661 atattagtat gggaggatca ggagtaccac gtaacgaatg aacctgccaa agtagaagaa
    21721 gttgggcaaa aacttggtga agtaacaaaa aaaattaaaa caagtaaaaa acctattaaa
    21781 aatagagaat ctaatacatt acaagagaaa acagaagtat tcacaatgat tgaggaagaa
    21841 aaagatcctc aatcaccttt aatcataaag gaaacttata gtgatgaata tagggtagtg
    21901 aggccgatgt tgaagcgggt attgtgatga aaaggagaat cttttgtaga cagtaatttc
    21961 gtatccgtgg gtgttaagaa aaactttttt cctttgtttt attttgtccc ctatcggtgc
    22021 cgcttgcatt ttgatgaata gaggagcaat acaaaagaga gatttcattt tatatttatt
    22081 atttgctgct atgaatatat cactttggtt attgcttatg atttttgatt ggagtatgtg
    22141 gatggtagta gggcattatt tgtttggagc agttgttatt gttttttcga atatgaataa
    22201 gagctaagcc agcaacctta aagttgctgg tttttatttt gctatttata atgaagaaac
    22261 aaataaatca atatgtaaag aaggaatggt atagataaaa gtaacgcctg aacggttaga
    22321 acagactgca aagacagtaa ataacatcag gcacttctta gaatacttac ataatgactt
    22381 atacaatcaa attaagaata tcgctataca atggaatgga gcgagtagag aacaatttta
    22441 acagagattt aacgaagtaa aaccaaaaat gtttaatgtt ttaatagaag ttaaaaacta
    22501 caatgtttat taatgaaatc tagtggtaga ctttcattaa taaacattgt agtaaaacag
    22561 ttggaagata gattgaaata tttgcccgaa ggttcacatc agactgtcgt gatagatgtg
    22621 agaggaccag atggaacgag agaaacattg aagtaaataa gagaagaaat aaatcaaaga
    22681 acatttggac aggcagaaat tatcattaaa aagatacaaa aaagtaggtt atattacaga
    22741 gttagcacaa atgcataagt tataatttca agtgccataa ggataaccct gaggagaaaa
    22801 aagacttctg atttttaaga ttatataaaa tattcatagt tgcaaaaact ctattgtggt
    22861 aaaatattct atataaatat ttaaaagggg aatggctatg ggggatataa aagttactcc
    22921 tgaacagttg cgaaaagtgg cagggactat tagatcaact atcacgaatg caactgcaac
    22981 acaggagcga ctaaaacgag atattgatat gatttctagt aattggttgg gctcagccta
    23041 tatgaaattt aatacggatt tccgtgattc atcctttaag atggcacaat ttataatcat
    23101 attggagcca cttgagaagt ttcttcttga ttctgctaat aaatttgaac aagtagataa
    23161 catggatgtt gctattgcgt tggcttccag tattttaact gggaaacctt ttaaagggga
    23221 ttacgaaact ttaacaggtg attttaaatt agcagaagga aatcgagtgg gaatgaaagc
    23281 agaaggttca ttgataaaag gtgaatatga gatttcgaaa ggaacaaagc ttacttttaa
    23341 agggggaaat ggctccttag agaccagtgt tccaatggat gaaaagacat ttattagtga
    23401 tgttgcagga gggggggtag taggctttaa agttggtgct tctctttttg aggactcaat
    23461 agaaaaagaa ataaatagcg gttttgcaga aaaagcaaca gttacac
//
